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Original Article

Prevalence of disease-specific antinuclear antibodies in general population: estimates from annual physical examinations of residents of a small town over a 5-year period

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Pages 153-160 | Received 12 Jun 2007, Accepted 02 Nov 2007, Published online: 02 Jan 2014

References

  • Tan EM. Antinuclear antibodies: diagnostic markers for auto-immune diseases and probes for cell biology. Adv Immunol. 1989;44:93–151.
  • Fujimoto M, Shimozuma M, Yazawa N, Kubo M, Ihn H, Sato S, et al. Prevalence and clinical relevance of 52-kDa and 60-kDa Ro/SS-A autoantibodies in Japanese patients with systemic sclerosis. Ann Rheum Dis. 1997;56:667–70.
  • Cleymaet JE, Nakamura RM. Indirect immunofluorescent anti-nuclear antibody tests: comparison of sensitivity and specificity of different substrates. Am J Clin Pathol. 1972;58:388–93.
  • Kozin F, Fowler M, Koethe SM. A comparison of the sensitivities and specificities of different substrates for the fluorescent anti-nuclear antibody test. Am J Clin Pathol. 1980;74:785–90.
  • Tan EM, Feltkamp TE, Smolen JS, Butcher B, Dawkins R, Fritzler MJ, et al. Range of antinuclear antibodies in "healthy" individuals. Arthritis Rheum. 1997; 40:1601–11.
  • Hayashi N, Kawamoto T, Mukai M, Morinobu A, Koshiba M, Kondo S, et al. Detection of antinuclear antibodies by use of an enzyme immunoassay with nuclear HEp-2 cell extract and recombinant antigens: comparison with immunofluorescence assay in 307 patients. Clin Chem. 2001;47:1649–59.
  • von Muhlen CA, Tan EM. Autoantibodies in the diagnosis of systemic rheumatic diseases. Semin Arthritis Rheum. 1995;24:323–58.
  • de Vlam K, De Keyser F, Verbruggen G, Vandenbossche M, Vanneuville B, D'Haese D, et al. Detection and identification of antinuclear autoantibodies in the serum of normal blood donors. Clin Exp Rheumatol. 1993;11:393–7.
  • Manoussakis MN, Tzioufas AG, Silis MP, Pange PJ, Goudevenos J, Moutsopoulos HM. High prevalence of anti-cardiolipin and other autoantibodies in a healthy elderly population. Clin Exp Immunol. 1987;69:557–65.
  • Azizah MR, Azila MN, Zulkifii MN, Norita TY. The prevalence of antinuclear, anti-dsDNA, anti-Sm and anti-RNP antibodies in a group of healthy blood donors. Asian Pac J Allergy Immunol. 1996;14:125–8.
  • Juby AG, Davis P, McElhaney JE, Gravenstein S. Prevalence of selected autoantibodies in different elderly subpopulations. Br J Rheumatol. 1994;33:1121–4.
  • Ruffatti A, Calligaro A, Del Ross T, Bertoli MT, Doria A, Rossi L, et al. Anti-double-stranded DNA antibodies in the healthy elderly: prevalence and characteristics. J Clin Immunol. 1990;10:300–3.
  • Murakami A, Kojima K, Ohya K, Imamura K, Takasaki Y. A new conformational epitope generated by the binding of recom-binant 70-kd protein and Ul RNA to anti-U1 RNP autoantibodies in sera from patients with mixed connective tissue disease. Arthritis Rheum. 2002;46: 3273–82.
  • Alspaugh MA, Tan EM. Antibodies to cellular antigens in Sjo-gren's syndrome. J Clin Invest. 1975;55:1067–73.
  • Wold RT, Young FE, Tan EM, Fan RS. Deoxyribonucleic acid antibody: a method to detect its primary interaction with deoxyribonucleic acid. Science. 1968;161:806–7.
  • Hansen KE, Amason J, Bridges AJ. Autoantibodies and common viral illnesses. Semin Arthritis Rheum. 1998;27:263–71.
  • Muller S, Boire G, Ossondo M, Ricchiuti V, Smadja D, Vernant JC, et al. IgG autoantibody response in HTLV-I-infected patients. Clin Immunol Immunopathol. 1995;77:282–90.
  • Vitali C, Bombardieri S, Moutsopoulos HM, Balestrieri G, Bencivelli W, Bernstein RM, et al. Preliminary criteria for the classification of Sjogren's syndrome. Results of a prospective concerted action supported by the European community. Arthritis Rheum. 1993;36:340–7.
  • Conrad K, Mehlhorn J. Diagnostic and prognostic relevance of autoantibodies in uranium miners. Int Arch Allergy Immunol. 2000;123:77–91.
  • Peene I, Meheus L, Veys EM, De Keyser F. Detection and identification of antinuclear antibodies (ANA) in a large and consecutive cohort of serum samples referred for ANA testing. Ann Rheum Dis. 2001;60:1131–6.
  • Ruffatti A, Artifoni L, Glorioso S, Calligaro A, Doria A, Gambari P, et al. Prevalence of anticentromere antibody in blood relatives of anticentromere positive patients. J Rheumatol. 1985;12:940–3.
  • Soma Y, Takehara K, Ishibashi Y. Clinical distribution of anti-centromere antibody in Japanese patients. Dermatologica. 1989;178:16–9.
  • Spiewak R, Stojek N. Antinuclear antibodies among eastern-Polish rural inhabitants. Ann Agric Environ Med. 2003;10:207–9.
  • Keech CL, McCluskey J, Gordon TP. Transfection and overex-pression of the human 60-kDa Ro/SS-A autoantigen in HEp-2 cells. Clin Immunol Immunopathol. 1994;73: 146–51.
  • Tan EM, Smolen JS, McDougal JS, Butcher BT, Conn D, Dawkins R, et al. A critical evaluation of enzyme immunoassays for detection of antinuclear autoantibodies of defined specifici-ties. I. Precision, sensitivity, and specificity. Arthritis Rheum. 1999;42:455–64.
  • Tan EM, Smolen JS, McDougal JS, Fritzler MJ, Gordon T, Hardin JA, et al. A critical evaluation of enzyme immunoassay kits for detection of antinuclear autoantibodies of defined specificities. II. Potential for quantitation of antibody content. J Rheumatol. 2002;29:68–74.
  • Adebajo AO, Charles P, Maini RN, Hazleman BL. Autoanti-bodies in malaria, tuberculosis and hepatitis B in a west African population. Clin Exp Immunol 1993;92:73–6.
  • Clifford BD, Donahue D, Smith L, Cable E, Luttig B, Manns M, et al. High prevalence of serological markers of autoimmunity in patients with chronic hepatitis C. Hepatology. 1995;21:613–9.
  • Li L, Chen M, Huang DY, Nishioka M. Frequency and signifi-cance of antibodies to chromatin in autoimmune hepatitis type I. J Gastroenterol Hepatol. 2001;16:245–7.
  • Maricq HR, Harper FE, Khan MM, Tan EM, LeRoy EC. Microvascular abnormalities as possible predictors of disease subsets in Raynaud phenomenon and early connective tissue disease. Clin Exp Rheumatol. 1983;1:195–205.
  • Bernstein RM, Callender ME, Neuberger JM, Hughes GR, Wil-liams R. Anticentromere antibody in primary biliary cirrhosis. Ann Rheum Dis. 1982;41:612–4.
  • Arbuckle MR, McClain MT, Rubertone MV, Scofield RH, Dennis GJ, James JA, et al. Development of autoantibodies before the clinical onset of systemic lupus erythematosus. N Engl J Med. 2003;349:1526–33.

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