98
Views
33
CrossRef citations to date
0
Altmetric
Original Article

Vitamin K2 administration is associated with decreased disease activity in patients with rheumatoid arthritis

, , , , , , & show all
Pages 1001-1007 | Received 31 Jul 2012, Accepted 18 Oct 2012, Published online: 02 Jan 2014

REFERENCES

  • Liu Y, Nelson AN, Lipsky JJ. Vitamin K-dependent carboxylase: mRNA distribution and effects of vitamin K deficiency and warfarin treatment. Biochem Biophys Res Commun. 1996;224: 549–54.
  • Yamaguchi M, Taguchi H, Gao YH, Igarashi A, Tsukamoto Y. Effect of vitamin IC2 (menaquinone-7) in fermented soybean (natto) on bone loss in ovariectomized rats. J Bone Miner Metab. 1999;17: 23–9.
  • Akiyama Y, Hara K, Tajima T, Murota S, Morita I. Effect of vitamin K2 (menatetrenone) on osteoclast-like cell formation in mouse bone marrow cultures. Eur J Pharmacol. 1994;263: 181–5.
  • Hirao M, Hashimoto J, Ando W, Ono T, Yoshikawa H. Response of serum carboxylated and undercarboxylated osteocalcin to alendronate monotherapy and combined therapy with vitamin K2 in postmenopausal women. J Bone Miner Metab. 2008;26: 260–4.
  • Suzuki K, Tsuji S, Fukushima Y, Nakase T, Hamada M, Tomita T, et al. Clinical results of alendronate monotherapy and com-bined therapy with menatetrenone (VitK(2)) in postmenopausal RA patients. Mod Rheumatol. 2012 (in press).
  • Suttie JW. Synthesis of vitamin K-dependent proteins. FASEB J. 1993;7:445–52.
  • Yaguchi M, Miyazawa K, Katagiri T, Nishimaki J, Kizaki M, Tohyama K, et al. Vitamin K2 and its derivatives induce apop-tosis in leukemia cells and enhance the effect of all-trans retinoic acid. Leukemia. 1997;11:779–87.
  • Yaguchi M, Miyazawa K, Otawa M, Katagiri T, Nishimaki J, Uchida Y, et al. Vitamin K2 selectively induces apoptosis of blastic cells in myelodysplastic syndrome: flow cytometric detection of apoptotic cells using AP02.7 monoclonal antibody. Leukemia. 1998;12:1392–7.
  • Fujita H, Tomiyama J, Tanaka T. Vitamin K2 combined with all-trans retinoic acid induced complete remission of relapsing acute promyelocytic leukaemia. Br J Haematol. 1998;103: 584–5.
  • Miyazawa K, Nishimaki J, Ohyashiki K, Enomoto S, Kuriya S, Fukuda R, et al. Vitamin K2 therapy for myelodysplastic syn-dromes (MDS) and post-MDS acute myeloid leukemia: infor-mation through a questionnaire survey of multi-center pilot studies in Japan. Leukemia. 2000;14:1156–7.
  • Qu Z, Garcia CH, O'Rourke LM, Planck SR, Kohli M, Rosen-baum JT. Local proliferation of fibroblast-like synoviocytes contributes to synovial hyperplasia. Results of proliferating cell nuclear antigen/cyclin, c-myc, and nucleolar organizer region staining. Arthritis Rheum. 1994;37:212–20.
  • Nakazawa F, Matsuno H, Yudoh K, Katayama R, Sawai T, Uzuki M, et al. Methotrexate inhibits rheumatoid synovitis by inducing apoptosis. J Rheumatol. 2001;28:1800–8.
  • Okamoto H, Shidara K, Hoshi D, Kamatani N. Anti-arthritis effects of vitamin K(2) (menaquinone-4)-a new potential therapeutic strategy for rheumatoid arthritis. FEBS J. 2007;274:4588–94.
  • Arnett FC, Edworthy SM, Bloch DA, McShane DJ, Fries JF, Cooper NS, et al. The American Rheumatism Association 1987 revised criteria for the classification of rheumatoid arthritis. Arthritis Rheum. 1988;31:315–24.
  • Inoue E, Yamanaka H, Hara M, Tomatsu T, Kamatani N. Com-parison of Disease Activity Score (DAS)28-erythrocyte sedi-mentation rate and DA528-C-reactive protein threshold values. Ann Rheum Dis. 2007;66: 407–9.
  • Steinbrocker 0, Traeger CH, Batterman RC. Therapeutic criteria in rheumatoid arthritis. J Am Med Assoc. 1949;140:659–62.
  • Hochberg MC, Chang RW, Dwosh I, Lindsey S, Pincus T, Wolfe F. The American College of Rheumatology 1991 revised criteria for the classification of global functional status in rheumatoid arthritis. Arthritis Rheum. 1992;35:498–502.
  • Catrina AT, Ulfgren AK, Lindblad S, Grondal L, Klareskog L. Low levels of apoptosis and high FLIP expression in early rheumatoid arthritis synovium. Ann Rheum Dis. 2002;61:934–6.
  • Franz JK, Pap T, Hummel KM, Nawrath M, Aicher WK, Shi-geyama Y, et al. Expression of sentrin, a novel antiapoptotic molecule, at sites of synovial invasion in rheumatoid arthritis. Arthritis Rheum. 2000;43:599–607.
  • Perlman H, Liu H, Georganas C, Koch AE, Shamiyeh E, Haines GK 3rd, et al. Differential expression pattern of the antiapoptotic proteins, Bc1-2 and FLIP, in experimental arthritis. Arthritis Rheum. 2001;44: 2899–908.
  • Schedel J, Gay RE, Kuenzler P, Seemayer C, Simmen B, Michel BA, et al. FLICE-inhibitory protein expression in synovial fibroblasts and at sites of cartilage and bone erosion in rheuma-toid arthritis. Arthritis Rheum. 2002;46:1512–8.
  • Kim WU, Yoo SA, Min SY, Park SH, Koh HS, Song SW, et al. Hydroxychloroquine potentiates Fas-mediated apoptosis of rheumatoid synoviocytes. Clin Exp Immunol. 2006;144:503–11.
  • Wunder A, Schellenberger E, Mahmood U, Bogdanov A Jr, Muller-Ladner U, Weissleder R, et al. Methotrexate-induced accumulation of fluorescent annexin V in collagen-induced arthritis. Mol Imaging. 2005;4:1–6.
  • Criddle DN, Gillies S, Baumgartner-Wilson HK, Jaffar M, Chinje EC, Passmore S, et al. Menadione-induced reactive oxygen species generation via redox cycling promotes apoptosis of murine pancreatic acinar cells. J Biol Chem. 2006;281:40485–92.
  • Mokuda S, Okuda Y, Onishi M, Sawada N, Matoba K, Yamada A, et al. Postmenopausal women with rheumatoid arthritis who are treated with raloxifene or alendronate or glucocorticoids have lower serum undercarboxylated osteocalcin (uc0C) levels. J Endocrinol Invest. 2012;35:661–4.
  • Oelzner P, Muller A, Deschner F, Huller M, Abendroth K, Hein G, et al. Relationship between disease activity and serum levels of vitamin D metabolites and PTH in rheumatoid arthritis. Calcif Tissue Int. 1998;62:193–8.
  • Muller K, Kriegbaum NJ, Baslund B, Sorensen OH, Thymann M, Bentzen K. Vitamin D3 metabolism in patients with rheumatic diseases: low serum levels of 25-hydroxyvitamin D3 in patients with systemic lupus erythematosus. Clin Rheumatol. 1995;14: 397–400.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.