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Original Article

Evaluation of costs associated with tolvaptan-mediated length-of-stay reduction among heart failure patients with hyponatremia in the US, based on the EVEREST trial

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Pages 276-284 | Accepted 18 Nov 2011, Published online: 08 Dec 2011

References

  • Haley H, Ploth DW. Dyshomeostasis of serum sodium concentration in congestive heart failure. Am J Med Sci 2010;340:42–7
  • Chen MC, Chang HW, Cheng CI, et al. Risk stratification of in-hospital mortality in patients hospitalized for chronic congestive heart failure secondary to non-ischemic cardiomyopathy. Cardiology 2003;100:136–42
  • Gheorghiade M, Gattis WA, O'Connor CM, et al. Effects of tolvaptan, a vasopressin antagonist, in patients hospitalized with worsening heart failure: a randomized controlled trial. JAMA 2004;291:1963-71
  • Gheorghiade M, Konstam MA, Burnett JC Jr., et al. Short-term clinical effects of tolvaptan, an oral vasopressin antagonist, in patients hospitalized for heart failure: the EVEREST Clinical Status Trials. JAMA 2007;297:1332-43
  • Gheorghiade M, Rossi JS, Cotts W, et al. Characterization and prognostic value of persistent hyponatremia in patients with severe heart failure in the ESCAPE Trial. Arch Intern Med 2007;167:1998-2005
  • Klein L, O'Connor CM, Leimberger JD, et al. Lower serum sodium is associated with increased short-term mortality in hospitalized patients with worsening heart failure: results from the Outcomes of a Prospective Trial of Intravenous Milrinone for Exacerbations of Chronic Heart Failure (OPTIME-CHF) study. Circulation 2005;111:2454-60
  • Triposkiadis F, Karayannis G, Giamouzis G, et al. The sympathetic nervous system in heart failure physiology, pathophysiology, and clinical implications. J Am Coll Cardiol 2009;54:1747-62
  • Francis GS, Goldsmith SR, Levine TB, et al. The neurohumoral axis in congestive heart failure. Ann Intern Med 1984;101:370-7
  • Oren RM. Hyponatremia in congestive heart failure. Am J Cardiol 2005;95:2B-7B
  • Lee CR, Watkins ML, Patterson JH, et al. Vasopressin: a new target for the treatment of heart failure. Am Heart J 2003;146:9-18
  • Sica DA. Hyponatremia and heart failure–treatment considerations. Congest Heart Fail 2006;12:55-60
  • Jao GT, Chiong JR. Hyponatremia in acute decompensated heart failure: mechanisms, prognosis, and treatment options. Clin Cardiol 2010;33:666-71
  • Sica DA. Sodium and water retention in heart failure and diuretic therapy: basic mechanisms. Cleve Clin J Med 2006;73(2 Suppl):S2-7; discussion S30–3
  • Gheorghiade M, Abraham WT, Albert NM, et al. Relationship between admission serum sodium concentration and clinical outcomes in patients hospitalized for heart failure: an analysis from the OPTIMIZE-HF registry. Eur Heart J 2007;28:980-8
  • Adrogue HJ. Consequences of inadequate management of hyponatremia. Am J Nephrol 2005;25:240-9
  • Lee WH, Packer M. Prognostic importance of serum sodium concentration and its modification by converting-enzyme inhibition in patients with severe chronic heart failure. Circulation 1986;73:257-67
  • Ferguson-Myrthil N. Novel agents for the treatment of hyponatremia: a review of conivaptan and tolvaptan. Cardiol Rev 2010;18:313-21
  • Konstam MA, Gheorghiade M, Burnett JC, Jr., et al. Effects of oral tolvaptan in patients hospitalized for worsening heart failure: the EVEREST Outcome Trial. JAMA 2007;297:1319-31
  • Cyr PL, Slawsky KA, Olchanski N, et al. Effect of serum sodium concentration and tolvaptan treatment on length of hospitalization in patients with heart failure. Am J Health Syst Pharm 2011;68:328-33
  • (HCUP), HCaUP, HCUP Nationwide Inpatient Sample (NIS). 2007–2009. Rockville, MD: Agency for Healthcare Research and Quality
  • Callahan MA, Do HT, Caplan DW, et al. Economic impact of hyponatremia in hospitalized patients: a retrospective cohort study. Postgrad Med 2009;121:186-91
  • Krumholz HM, Chen YT, Bradford WD, et al. Variations in and correlates of length of stay in academic hospitals among patients with heart failure resulting from systolic dysfunction. Am J Manag Care 1999;5:715-23
  • Mohammed AA, van Kimmenade RR, Richards M, et al. Hyponatremia, natriuretic peptides, and outcomes in acutely decompensated heart failure: results from the International Collaborative of NT-proBNP Study. Circ Heart Fail 2010;3:354-61
  • Panciroli C, Galloni G, Oddone A, et al. Prognostic value of hyponatremia in patients with severe chronic heart failure. Angiology 1990;41:631-8
  • Fang J, Mensah GA, Croft JB, et al. Heart failure-related hospitalization in the U.S., 1979 to 2004. J Am Coll Cardiol 2008;52:428-34
  • Lloyd-Jones D, Adams RJ, Brown TM, et al. Heart disease and stroke statistics–2010 update: a report from the American Heart Association. Circulation 2010;121:e46-e215
  • Shorr AF, Tabak YP, Johannes RS, et al. Burden of sodium abnormalities in patients hospitalized for heart failure. Congest Heart Fail 2011;17:1-7
  • Movig KL, Leufkens HG, Lenderink AW, et al. Validity of hospital discharge International Classification of Diseases (ICD) codes for identifying patients with hyponatremia. J Clin Epidemiol 2003;56:530-5
  • Shea AM, Curtis LH, Szczech LA, et al. Sensitivity of International Classification of Diseases codes for hyponatremia among commercially insured outpatients in the United States. BMC Nephrol 2008;9:5

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