995
Views
7
CrossRef citations to date
0
Altmetric
Research Article

Historical clinical and economic consequences of anemia management in patients with end-stage renal disease on dialysis using erythropoietin stimulating agents versus routine blood transfusions: a retrospective cost-effectiveness analysis

, , , , , & show all
Pages 293-304 | Accepted 22 Nov 2011, Published online: 16 Dec 2011

References

  • Goodnough LT, Brecher ME, Kanter MH, et al. Transfusion medicine. First of two parts – blood transfusion. N Engl J Med 1999;340:438-47
  • Mossey RT, Sondheimer J. Listeriosis in patients with long-term hemodialysis and transfusional iron overload. Am J Med 1985;79:397-400
  • Eschbach JW, Egrie JC, Downing MR, et al. Correction of the anemia of end-stage renal disease with recombinant human erythropoietin. Results of a combined phase I and II clinical trial. N Engl J Med 1987;316:73-8
  • Canadian Erythropoietin Study Group. Association between recombinant human erythropoietin and quality of life and exercise capacity of patients receiving haemodialysis. BMJ 1990;300:573-8
  • Churchill DN, Taylor DW, Cook RJ, et al. Canadian Hemodialysis Morbidity Study. Am J Kidney Dis 1992;19:214-34
  • Clement FM, Klarenbach S, Tonelli M, et al. An economic evaluation of erythropoiesis-stimulating agents in CKD. Am J Kidney Dis 2010;56:1050-61
  • Tonelli M, Winkelmayer WC, Jindal KK, et al. The cost-effectiveness of maintaining higher hemoglobin targets with erythropoietin in hemodialysis patients. Kidney Int 2003; 64:295-304
  • USRDS. 2008 Annual Data Report; 2008 Contract No.: Document Number
  • USRDS. 2005 Annual Data Report; 2005 Contract No.: Document Number
  • Fleurence RL, Hollenbeak CS. Rates and probabilities in economic modelling: transformation, translation and appropriate application. Pharmacoeconomics 2007;25:3-6
  • National Institute for Health and Clinical Excellence, CG39 Anaemia management in chronic kidney disease: full guideline, September 2006
  • Tonelli MK, Wiebe N, Shrive F, et al. Erythropoiesis-Stimulating Agents for Anemia of Chronic Kidney Disease: Systematic Review and Economic Evaluation. Ottowa: Canadian Agency for Drugs and Technologies in Health; 2008 Contract No.: Document Number
  • Rao PS, Schaubel DE, Jia X, et al. Survival on dialysis post-kidney transplant failure: results from the Scientific Registry of Transplant Recipients. Am J Kidney Dis 2007;49:294-300
  • Evans RW, Manninen DL, Garrison LP, Jr et al. The quality of life of patients with end-stage renal disease. N Engl J Med 1985;312:553-9
  • Finkelstein FO, Story K, Firanek C, et al. Health-related quality of life and hemoglobin levels in chronic kidney disease patients. Clin J Am Soc Nephrol 2009;4:33-8
  • Fryback DG, Lawrence WF, Martin PA, et al. Predicting Quality of Well-being scores from the SF-36: results from the Beaver Dam Health Outcomes Study. Med Decis Making 1997;17:1-9
  • Laupacis A, Keown P, Pus N, et al. A study of the quality of life and cost-utility of renal transplantation. Kidney Int 1996;50:235-42
  • Collins AJ, Li S, St Peter W, et al. Death, hospitalization, and economic associations among incident hemodialysis patients with hematocrit values of 36 to 39%. J Am Soc Nephrol 2001;12:2465-73
  • Xia H, Ebben J, Ma JZ, et al. Hematocrit levels and hospitalization risks in hemodialysis patients. J Am Soc Nephrol 1999;10:1309-16
  • Karpinski M, Pochinco D, Dembinski I, et al. Leukocyte reduction of red blood cell transfusions does not decrease allosensitization rates in potential kidney transplant candidates. J Am Soc Nephrol 2004;15:818-24
  • Eschbach JW, Abdulhadi MH, Browne JK, et al. Recombinant human erythropoietin in anemic patients with end-stage renal disease. Results of a phase III multicenter clinical trial. Ann Intern Med 1989;111:992-1000
  • Nissenson AR, Korbet S, Faber M, et al. Multicenter trial of erythropoietin in patients on peritoneal dialysis. J Am Soc Nephrol 1995;5:1517-29
  • Remak E, Hutton J, Jones M, et al. Changes in cost-effectiveness over time. The case of epoetin alfa for renal replacement therapy patients in the UK. Eur J Health Econ 2003;4:115-21
  • Eschbach JW, Adamson JW. Iron overload in renal failure patients: changes since the introduction of erythropoietin therapy. Kidney Int Suppl 1999;69:S35-43
  • Hakim RM, Stivelman JC, Schulman G, et al. Iron overload and mobilization in long-term hemodialysis patients. Am J Kidney Dis 1987;10:293-9
  • Schreiber GB, Busch MP, Kleinman SH, et al. The risk of transfusion-transmitted viral infections. The Retrovirus Epidemiology Donor Study. N Engl J Med 1996; 334:1685-90
  • Shander A, Hofmann A, Ozawa S, et al. Activity-based costs of blood transfusions in surgical patients at four hospitals. Transfusion 2010;50:753-65
  • Lee CP, Chertow GM, Zenios SA. An emperic estimate of the value of life: updating the renal dialysis cost-effectiveness standard. Value Health 2009;12:80-7
  • Shiroiwa T, Sung YK, Fukuda T, et al. International survey on willingness-to-pay (WTP) for one additional AQLY gained: what is the threshold of cost effectiveness? Health Econ 2010;19:422-37
  • Menzin J, Lines LM, Weiner DE, et al. A review of the costs and cost effectiveness of interventions in chronic kidney disease: implications for policy. Pharmacoeconomics 2011;29:839-61
  • Drueke TB, Locatelli F, Clyne N, et al. Normalization of hemoglobin level in patients with chronic kidney disease and anemia. N Engl J Med 2006;355:2071-84
  • Pfeffer MA, Burdmann EA, Chen CY, et al. A trial of darbepoetin alfa in type 2 diabetes and chronic kidney disease. N Engl J Med 2009;361:2019-32
  • Singh AK, Szczech L, Tang KL, et al. Correction of anemia with epoetin alfa in chronic kidney disease. N Engl J Med 2006;355:2085-98
  • KDOQI Clinical Practice Guideline and Clinical Practice Recommendations for Anemia in Chronic Kidney Disease: 2007 Update of Hemoglobin Target. Available at: http://www.kidney.org/professionals/KDOQI/guidelines_anemiaUP/guide1.htm. Accessed on: November 9, 2011
  • Ebben JP, Gilbertson DT, Foley RN, et al. Hemoglobin level variability: associations with comorbidity, intercurrent events, and hospitalizations. Clin J Am Soc Nephrol 2006;1:1205-10
  • Marsden PA. Treatment of anemia in chronic kidney disease – strategies based on evidence. N Engl J Med 2009;361:2089-90
  • Lee H, Manns B, Taub K, et al. Cost analysis of ongoing care of patients with end-stage renal disease: the impact of dialysis modality and dialysis access. Am J Kidney Dis 2002;40:611-22
  • Cantor SB, Hudson DV, Jr., Lichtiger B, et al. Costs of blood transfusion: a process-flow analysis. J Clin Oncol 1998;16:2364-70
  • Payne KA, Desrosiers MP, Caro JJ, et al. Clinical and economic burden of infused iron chelation therapy in the United States. Transfusion 2007;47:1820-9
  • Coyle D, Lee KM, Fergusson DA, et al. Cost effectiveness of epoetin-alpha to augment preoperative autologous blood donation in elective cardiac surgery. Pharmacoeconomics 2000;18:161-71

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.