Increased protein processing gene signature in HDACi-resistant cells predicts response to proteasome inhibitors

Daphné Dupéré-RicherSegal Cancer Center, Lady Davis Institute for Medical Research, McGill University, Montréal, QC, Canada;

Mena KinalSegal Cancer Center, Lady Davis Institute for Medical Research, McGill University, Montréal, QC, Canada;

Filippa PetterssonSegal Cancer Center, Lady Davis Institute for Medical Research, McGill University, Montréal, QC, Canada;

Audrey EmondSegal Cancer Center, Lady Davis Institute for Medical Research, McGill University, Montréal, QC, Canada;

M. Nieves Calvo-VidalDivision of Hematology and Oncology, Department of Medicine, Cornell University, New York, NY, USA;

Jessica N. NicholSegal Cancer Center, Lady Davis Institute for Medical Research, McGill University, Montréal, QC, Canada;

Cynthia GuilbertSegal Cancer Center, Lady Davis Institute for Medical Research, McGill University, Montréal, QC, Canada;

Dany PlourdeSegal Cancer Center, Lady Davis Institute for Medical Research, McGill University, Montréal, QC, Canada;

Kathleen Klein OrosSegal Cancer Center, Lady Davis Institute for Medical Research, McGill University, Montréal, QC, Canada;

Torsten H. NielsenSegal Cancer Center, Lady Davis Institute for Medical Research, McGill University, Montréal, QC, Canada;

Teresa EzpondaDivision of Hematology/Oncology, Robert. H. Lurie Comprehensive Cancer Center, Northwestern University, Feinberg School of Medicine, Chicago, IL, USA

Jonathan D. LichtDivision of Hematology/Oncology, Robert. H. Lurie Comprehensive Cancer Center, Northwestern University, Feinberg School of Medicine, Chicago, IL, USA

Nathalie A. JohnsonSegal Cancer Center, Lady Davis Institute for Medical Research, McGill University, Montréal, QC, Canada;

Sarit AssoulineSegal Cancer Center, Lady Davis Institute for Medical Research, McGill University, Montréal, QC, Canada;

Leandro CerchiettiDivision of Hematology and Oncology, Department of Medicine, Cornell University, New York, NY, USA;

Wilson H. Miller Jr.Segal Cancer Center, Lady Davis Institute for Medical Research, McGill University, Montréal, QC, Canada; Correspondence[email protected]; [email protected]

Koren K. MannSegal Cancer Center, Lady Davis Institute for Medical Research, McGill University, Montréal, QC, Canada; Correspondence[email protected]; [email protected]

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Increased protein processing gene signature in HDACi-resistant cells predicts response to proteasome inhibitors

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Increased protein processing gene signature in HDACi-resistant cells predicts response to proteasome inhibitors

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