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RALE051: a novel established cell line of sporadic Burkitt lymphoma

Alberto L’AbbateDepartment of Biology, University of Bari, Bari, Italy; Correspondence[email protected]

Ilaria IacobucciDepartment of Experimental, Diagnostic and Specialty Medicine, Institute of Hematology “Seràgnoli”, University of Bologna, Bologna, Italy;

Angelo LonoceDepartment of Biology, University of Bari, Bari, Italy;

Antonella TurchianoDepartment of Biology, University of Bari, Bari, Italy;

Elisa FicarraDepartment of Computer and Control Engineering, Politecnico di Torino, Torino, Italy;

Giulia PacielloDepartment of Computer and Control Engineering, Politecnico di Torino, Torino, Italy;

Federica CattinaChair of Haematology, Stem Cell Transplantation Unit, University of Brescia, Piazzale Spedali Civili 1, Brescia, Italy;

Anna FerrariDepartment of Experimental, Diagnostic and Specialty Medicine, Institute of Hematology “Seràgnoli”, University of Bologna, Bologna, Italy;

Enrica ImbrognoDepartment of Experimental, Diagnostic and Specialty Medicine, Institute of Hematology “Seràgnoli”, University of Bologna, Bologna, Italy;

Claudio AgostinelliDepartment of Experimental, Diagnostic and Specialty Medicine, Institute of Hematology “Seràgnoli”, University of Bologna, Bologna, Italy;

Pierluigi ZinzaniDepartment of Experimental, Diagnostic and Specialty Medicine, Institute of Hematology “Seràgnoli”, University of Bologna, Bologna, Italy;

Giovanni MartinelliDepartment of Experimental, Diagnostic and Specialty Medicine, Institute of Hematology “Seràgnoli”, University of Bologna, Bologna, Italy;

Enrico DerenziniHaemolymphopathology Unit, Department of Haematology and Oncology “Seràgnoli”, S. Orsola-Malpighi Hospital, Bologna, Italy

Clelia Tiziana StorlazziDepartment of Biology, University of Bari, Bari, Italy;

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RALE051: a novel established cell line of sporadic Burkitt lymphoma

Supplemental Methods

ICMJE Form for Disclosure of Potential Conflicts of Interest

Supplemental Table 3. List of missense, nonsense, and frameshift mutations.

Supplemental Table 2. Chimeric transcripts identified and prioritized by FuGePrior.

Supplemental Table 1

Supplemental Figure 5: Mutational status of TP53 in RALE051 cells.

Supplemental Figure 4: FuGePrior workflow and filters.

Supplemental Figure 3: Schematic representation of the molecular composition of the large marker chromosome in RALE051.

Supplemental Figure 2: Classical cytogenetic analysis of RALE051 and patient's constitutional karyotype.

Supplemental Figure 1: RALE051 Immunophenotype.

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RALE051: a novel established cell line of sporadic Burkitt lymphoma

Supplemental Methods

ICMJE Form for Disclosure of Potential Conflicts of Interest

Supplemental Table 3. List of missense, nonsense, and frameshift mutations.

Supplemental Table 2. Chimeric transcripts identified and prioritized by FuGePrior.

Supplemental Table 1

Supplemental Figure 5: Mutational status of TP53 in RALE051 cells.

Supplemental Figure 4: FuGePrior workflow and filters.

Supplemental Figure 3: Schematic representation of the molecular composition of the large marker chromosome in RALE051.

Supplemental Figure 2: Classical cytogenetic analysis of RALE051 and patient's constitutional karyotype.

Supplemental Figure 1: RALE051 Immunophenotype.

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