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Journal of Enzyme Inhibition and Medicinal Chemistry Volume 37, 2022 - Issue 1
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Research Papers

Topo II inhibition and DNA intercalation by new phthalazine-based derivatives as potent anticancer agents: design, synthesis, anti-proliferative, docking, and in vivo studies

Mohamed M. Khalifaa Pharmaceutical Medicinal Chemistry & Drug Design Department, Faculty of Pharmacy (Boys), Al-Azhar University, Cairo, EgyptCorrespondence[email protected]
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Ahmed A. Al-Karmalawyb Department of Pharmaceutical Medicinal Chemistry, Faculty of Pharmacy, Horus University-Egypt, New Damietta, EgyptView further author information
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Eslam B. Elkaeedc Department of Pharmaceutical Sciences, College of Pharmacy, AlMaarefa University, Riyadh, Saudi ArabiaView further author information
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Mohamed S. Nafied Chemistry Department, Faculty of Science, Suez Canal University, Ismailia, EgyptORCID Iconhttps://orcid.org/0000-0003-4454-6390View further author information
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Mohamed A. Tantawye Hormones Department, Medical Research and Clinical Studies Institute, National Research Centre, Dokki, Egypt;f Stem Cells Lab, Center of Excellence for Advanced Sciences, National Research Centre, Dokki, Cairo, EgyptView further author information
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Ibrahim H. Eissaa Pharmaceutical Medicinal Chemistry & Drug Design Department, Faculty of Pharmacy (Boys), Al-Azhar University, Cairo, EgyptView further author information
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Hazem A. Mahdya Pharmaceutical Medicinal Chemistry & Drug Design Department, Faculty of Pharmacy (Boys), Al-Azhar University, Cairo, EgyptCorrespondence[email protected]
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Pages 299-314 | Received 19 Oct 2021, Accepted 12 Nov 2021, Published online: 11 Dec 2021

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