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Journal of Enzyme Inhibition and Medicinal Chemistry Volume 37, 2022 - Issue 1
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Research Papers

2-Arylquinolines as novel anticancer agents with dual EGFR/FAK kinase inhibitory activity: synthesis, biological evaluation, and molecular modelling insights

Mostafa M. Elbadawia Department of Chemistry, Graduate School of Science, Hiroshima University, Hiroshima, Japan;b Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Kafrelsheikh University, Kafrelsheikh, EgyptCorrespondence[email protected]
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Wagdy M. Eldehnab Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Kafrelsheikh University, Kafrelsheikh, EgyptCorrespondence[email protected]
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Amer Ali Abd El-Hafeezc Pharmacology and Experimental Oncology Unit, Cancer Biology Department, National Cancer Institute, Cairo University, Cairo, Egypt;d Department of Cellular and Molecular Medicine, University of California San Diego, La Jolla, CA, USAView further author information
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Warda R. Somaae Faculty of Pharmacy, Kafrelsheikh University, Kafrelsheikh, EgyptView further author information
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Amgad Albohyf Department of Pharmaceutical Chemistry, Faculty of Pharmacy, The British University in Egypt (BUE), Cairo, EgyptView further author information
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Sara T. Al-Rashoodg Department of Pharmaceutical Chemistry, College of Pharmacy, King Saud University, Riyadh, Saudi ArabiaView further author information
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Keli K. Agamah Developmental Therapeutics Branch, Laboratory of Molecular Pharmacology, Center for Cancer Research, National Cancer Institute, NIH, Bethesda, MD, USAView further author information
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Eslam B. Elkaeedi Department of Pharmaceutical Sciences, College of Pharmacy, AlMaarefa University, Riyadh, Saudi ArabiaView further author information
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Pradipta Ghoshd Department of Cellular and Molecular Medicine, University of California San Diego, La Jolla, CA, USA;j Department of Medicine, University of California San Diego, La Jolla, CA, USA;k Moores Comprehensive Cancer Center, University of California San Diego, La Jolla, CA, USA;l Veterans Affairs Medical Center, La Jolla, CA, USAView further author information
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Yves Pommierh Developmental Therapeutics Branch, Laboratory of Molecular Pharmacology, Center for Cancer Research, National Cancer Institute, NIH, Bethesda, MD, USAView further author information
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Manabu Abea Department of Chemistry, Graduate School of Science, Hiroshima University, Hiroshima, JapanCorrespondence[email protected]
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Pages 355-378 | Received 12 Nov 2021, Accepted 01 Dec 2021, Published online: 20 Dec 2021

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