Rational design and synthesis of 2-(1H-indazol-6-yl)-1H-benzo[d]imidazole derivatives as inhibitors targeting FMS-like tyrosine kinase 3 (FLT3) and its mutants

Daseul Ima Department of Pharmacy, College of Pharmacy, Hanyang University, Ansan, Korea;b Institute of Pharmaceutical Science and Technology, Center for Proteinopathy, Hanyang University, Ansan, KoreaView further author information

Joonhong Juna Department of Pharmacy, College of Pharmacy, Hanyang University, Ansan, Korea;b Institute of Pharmaceutical Science and Technology, Center for Proteinopathy, Hanyang University, Ansan, KoreaView further author information

Jihyun Baeka Department of Pharmacy, College of Pharmacy, Hanyang University, Ansan, Korea;b Institute of Pharmaceutical Science and Technology, Center for Proteinopathy, Hanyang University, Ansan, KoreaView further author information

Haejin Kima Department of Pharmacy, College of Pharmacy, Hanyang University, Ansan, Korea;b Institute of Pharmaceutical Science and Technology, Center for Proteinopathy, Hanyang University, Ansan, KoreaView further author information

Dahyun Kanga Department of Pharmacy, College of Pharmacy, Hanyang University, Ansan, Korea;b Institute of Pharmaceutical Science and Technology, Center for Proteinopathy, Hanyang University, Ansan, KoreaView further author information

Hyunah Baea Department of Pharmacy, College of Pharmacy, Hanyang University, Ansan, Korea;b Institute of Pharmaceutical Science and Technology, Center for Proteinopathy, Hanyang University, Ansan, KoreaView further author information

Hyunwook Choa Department of Pharmacy, College of Pharmacy, Hanyang University, Ansan, Korea;b Institute of Pharmaceutical Science and Technology, Center for Proteinopathy, Hanyang University, Ansan, KoreaView further author information

Jung-Mi Haha Department of Pharmacy, College of Pharmacy, Hanyang University, Ansan, Korea;b Institute of Pharmaceutical Science and Technology, Center for Proteinopathy, Hanyang University, Ansan, KoreaCorrespondence[email protected]
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Rational design and synthesis of 2-(1H-indazol-6-yl)-1H-benzo[d]imidazole derivatives as inhibitors targeting FMS-like tyrosine kinase 3 (FLT3) and its mutants

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Rational design and synthesis of 2-(1H-indazol-6-yl)-1H-benzo[d]imidazole derivatives as inhibitors targeting FMS-like tyrosine kinase 3 (FLT3) and its mutants

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