Ligand-based design and synthesis of N'-Benzylidene-3,4-dimethoxybenzohydrazide derivatives as potential antimicrobial agents; evaluation by in vitro, in vivo, and in silico approaches with SAR studies

Rogy R. Ezz Eldina Pharmaceutical Organic Chemistry Department, Faculty of Pharmacy, Port Said University, Port Said, Egypt

Marwa A. Salehb Pharmaceutical Organic Chemistry Department, Faculty of Pharmacy (Girls), Al-Azhar University, Cairo, EgyptCorrespondence[email protected]

https://orcid.org/0000-0003-0767-9864

Mohammad Hayal Alotaibic National Center for Chemical Technologies, King Abdulaziz City for Science and Technology, Riyadh, Saudi Arabia

Reem K. Alsuairc National Center for Chemical Technologies, King Abdulaziz City for Science and Technology, Riyadh, Saudi Arabia

Yahya A. Alzahranic National Center for Chemical Technologies, King Abdulaziz City for Science and Technology, Riyadh, Saudi Arabia

Feras A. Alshehric National Center for Chemical Technologies, King Abdulaziz City for Science and Technology, Riyadh, Saudi Arabia

Amany F. Mohamedd Department of Anatomy and Embryology, Faculty of Medicine for Girls, Al-Azhar University, Cairo, Egypt

Shaimaa M. Hafezd Department of Anatomy and Embryology, Faculty of Medicine for Girls, Al-Azhar University, Cairo, Egypt

Azza Ali Althoqapye Department of Microbiology and Immunology, Faculty of Medicine for Girls, Al-Azhar University, Cairo, Egypt

Seham K. Khiralae Department of Microbiology and Immunology, Faculty of Medicine for Girls, Al-Azhar University, Cairo, Egypt

Mona M. Aminf Department of Pharmacology, Faculty of Medicine for Girls, Al-Azhar University, Cairo, Egypt

Yousuf A. Fg Department of Physiology, Faculty of Medicine for Girls, Al-Azhar University, Cairo, Egypt

Azza H. AbdElwahabg Department of Physiology, Faculty of Medicine for Girls, Al-Azhar University, Cairo, Egypt

Mohamed S. Alesawyh Pharmaceutical Medicinal Chemistry and Drug Design Department, Faculty of Pharmacy (Boys), Al‐Azhar University, Cairo, Egypt

Ayman Abo Elmaatyi Department of Medicinal Chemistry, Faculty of Pharmacy, Port Said University, Port Said, Egypt

Ahmed A. Al-Karmalawyj Department of Pharmaceutical Medicinal Chemistry, Faculty of Pharmacy, Horus University-Egypt, New Damietta, EgyptCorrespondence[email protected]

https://orcid.org/0000-0002-8173-6073

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Ligand-based design and synthesis of N'-Benzylidene-3,4-dimethoxybenzohydrazide derivatives as potential antimicrobial agents; evaluation by in vitro, in vivo, and in silico approaches with SAR studies

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Ligand-based design and synthesis of N'-Benzylidene-3,4-dimethoxybenzohydrazide derivatives as potential antimicrobial agents; evaluation by in vitro, in vivo, and in silico approaches with SAR studies

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