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Journal of Enzyme Inhibition and Medicinal Chemistry Volume 37, 2022 - Issue 1
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Research Papers

Design, synthesis and biological evaluation of novel triazoloquinazolinone and imidazoquinazolinone derivatives as allosteric inhibitors of SHP2 phosphatase

Wenjun Yea School of Pharmaceutical Sciences, Guizhou University, Guiyang, China; ;b Guizhou Engineering Laboratory for Synthetic Drugs, Guiyang, China; View further author information
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Ye Liua School of Pharmaceutical Sciences, Guizhou University, Guiyang, China; ;b Guizhou Engineering Laboratory for Synthetic Drugs, Guiyang, China; View further author information
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Qian Rena School of Pharmaceutical Sciences, Guizhou University, Guiyang, China; ;b Guizhou Engineering Laboratory for Synthetic Drugs, Guiyang, China; View further author information
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Tianhui Liaoa School of Pharmaceutical Sciences, Guizhou University, Guiyang, China; ;b Guizhou Engineering Laboratory for Synthetic Drugs, Guiyang, China; View further author information
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Yumei Chena School of Pharmaceutical Sciences, Guizhou University, Guiyang, China; ;b Guizhou Engineering Laboratory for Synthetic Drugs, Guiyang, China; View further author information
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Dongmei Chena School of Pharmaceutical Sciences, Guizhou University, Guiyang, China; ;b Guizhou Engineering Laboratory for Synthetic Drugs, Guiyang, China; View further author information
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Sisi Wanga School of Pharmaceutical Sciences, Guizhou University, Guiyang, China; ;b Guizhou Engineering Laboratory for Synthetic Drugs, Guiyang, China; View further author information
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Lihong Yaoa School of Pharmaceutical Sciences, Guizhou University, Guiyang, China; ;b Guizhou Engineering Laboratory for Synthetic Drugs, Guiyang, China; View further author information
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Yihe Jiac Department of Medicinal Chemistry, China Pharmaceutical University, Nanjing, ChinaView further author information
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Chunshen Zhaoa School of Pharmaceutical Sciences, Guizhou University, Guiyang, China; ;b Guizhou Engineering Laboratory for Synthetic Drugs, Guiyang, China; View further author information
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Zhixu Zhoua School of Pharmaceutical Sciences, Guizhou University, Guiyang, China; ;b Guizhou Engineering Laboratory for Synthetic Drugs, Guiyang, China; Correspondence[email protected]
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Pages 1495-1513 | Received 08 Feb 2022, Accepted 13 May 2022, Published online: 29 May 2022

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