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Journal of Enzyme Inhibition and Medicinal Chemistry Volume 37, 2022 - Issue 1
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Research Papers

Discovery of novel thiazolyl-pyrazolines as dual EGFR and VEGFR-2 inhibitors endowed with in vitro antitumor activity towards non-small lung cancer

Esraa A. Abdelsalama Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Helwan University, Cairo, EgyptCorrespondence[email protected] [email protected]
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Amer Ali Abd El-Hafeezb Department of Cellular and Molecular Medicine, University of California San Diego, La Jolla, CA, USA;c Pharmacology and Experimental Oncology Unit, Department of Cancer Biology, National Cancer Institute, Cairo University, Cairo, EgyptCorrespondence[email protected] [email protected]
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Wagdy M. Eldehnad Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Kafrelsheikh University, Kafrelsheikh, Egypt;e School of Biotechnology, Badr University in Cairo, Badr City, Cairo, EgyptView further author information
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Mahmoud A. El Hassabf Department of Medicinal Chemistry, Faculty of Pharmacy, King Salman International University (KSIU), South Sinai, EgyptView further author information
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Hala Mohamed M. Marzoukb Department of Cellular and Molecular Medicine, University of California San Diego, La Jolla, CA, USA;g Department of Biochemistry, Faculty of Medicine, Minia University, El-Minia, EgyptView further author information
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Mahmoud M. Elaasserh The Regional Center for Mycology and Biotechnology, Al-Azhar University, Cairo, EgyptView further author information
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Nageh A. Abou Taleba Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Helwan University, Cairo, EgyptView further author information
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Kamilia M. Amini Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Cairo University, Cairo, EgyptView further author information
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Hatem A. Abdel-Azizj Department of Applied Organic Chemistry, National Research Centre, Dokki, Giza, EgyptView further author information
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Pradipta Ghoshb Department of Cellular and Molecular Medicine, University of California San Diego, La Jolla, CA, USA;k Department of Medicine, University of California San Diego, La Jolla, CA, USA;l Moores Comprehensive Cancer Center, University of California San Diego, La Jolla, CA, USA;m Veterans Affairs Medical Center, La Jolla, CA, USAView further author information
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Sherif F. Hammada Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Helwan University, Cairo, Egypt;n PharmD Program and Basic and Applied Sciences Institute, Egypt-Japan University of Science and Technology (E-JUST), Alexandria, EgyptCorrespondence[email protected]
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Pages 2265-2282 | Received 31 May 2022, Accepted 18 Jul 2022, Published online: 23 Aug 2022

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