Novel pyrimidine Schiff bases and their selenium-containing nanoparticles as dual inhibitors of CDK1 and tubulin polymerase: design, synthesis, anti-proliferative evaluation, and molecular modelling

Samar El-Kalyoubia Department of Pharmaceutical Organic Chemistry, Faculty of Pharmacy, Port Said University, Port Said, EgyptCorrespondence[email protected] [email protected]

https://orcid.org/0000-0002-4648-5184 View further author information

Samiha A. El-Sebaeyb Department of Pharmaceutical Organic Chemistry, Faculty of Pharmacy (Girls), Al-Azhar University, Cairo, EgyptCorrespondence[email protected]

https://orcid.org/0000-0002-9928-9080 View further author information

Ahmed A. El-Sayedc Photochemistry Department, Chemical Industries Research Institute, National Research Centre, Giza, EgyptView further author information

Moustafa S. Abdelhamidd Department of Biochemistry, Faculty of Science, Zagazig University, Zagazig, EgyptView further author information

Fatimah Agilie Chemistry Department, Faculty of Science (Female Section), Jazan University, Jazan, Saudi ArabiaView further author information

Sherin M. Elfekyf Department of Pharmaceutical Organic Chemistry, Faculty of Pharmacy, Mansoura University, Mansoura, EgyptView further author information

Novel pyrimidine Schiff bases and their selenium-containing nanoparticles as dual inhibitors of CDK1 and tubulin polymerase: design, synthesis, anti-proliferative evaluation, and molecular modelling

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Novel pyrimidine Schiff bases and their selenium-containing nanoparticles as dual inhibitors of CDK1 and tubulin polymerase: design, synthesis, anti-proliferative evaluation, and molecular modelling

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