Design, synthesis and evaluation of dihydro-1H-indene derivatives as novel tubulin polymerisation inhibitors with anti-angiogenic and antitumor potency

Shengtao Xua Department of Hepatobiliary Surgery, China Medical University, The First People’s Hospital of Kunshan, Suzhou, P. R. China;b Department of Medicinal Chemistry, China Pharmaceutical University, Nanjing, P. R. ChinaView further author information

Yijun Sunc Jiangsu KeyGEN BioTECH Co., Ltd, Nanjing, P. R. ChinaView further author information

Peng Wangd Department of Neurosurgery, China Medical University, The First People’s Hospital of Kunshan, Suzhou, Jiangsu, P. R. ChinaView further author information

Yuchen Tanb Department of Medicinal Chemistry, China Pharmaceutical University, Nanjing, P. R. ChinaView further author information

Lei Shid Department of Neurosurgery, China Medical University, The First People’s Hospital of Kunshan, Suzhou, Jiangsu, P. R. ChinaCorrespondence[email protected]
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Jian Chena Department of Hepatobiliary Surgery, China Medical University, The First People’s Hospital of Kunshan, Suzhou, P. R. ChinaCorrespondence[email protected]

https://orcid.org/0000-0002-7137-7564 View further author information

Design, synthesis and evaluation of dihydro-1H-indene derivatives as novel tubulin polymerisation inhibitors with anti-angiogenic and antitumor potency

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Design, synthesis and evaluation of dihydro-1H-indene derivatives as novel tubulin polymerisation inhibitors with anti-angiogenic and antitumor potency

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