Design, synthesis, and biological investigation of selective human carbonic anhydrase II, IX, and XII inhibitors using 7-aryl/heteroaryl triazolopyrimidines bearing a sulfanilamide scaffold

Romeo Romagnolia Department of Chemical, Pharmaceutical and Agricultural Sciences, University of Ferrara, Ferrara, ItalyCorrespondence[email protected]
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Tiziano De Venturaa Department of Chemical, Pharmaceutical and Agricultural Sciences, University of Ferrara, Ferrara, ItalyView further author information

Stefano Manfredinib Department of Life Sciences and Biotechnology, University of Ferrara, Ferrara, ItalyView further author information

Erika Baldinib Department of Life Sciences and Biotechnology, University of Ferrara, Ferrara, ItalyView further author information

Claudiu T. Supuranc Department of NEUROFARBA, Section of Pharmaceutical and Nutraceutical Sciences, University of Florence, Florence, ItalyCorrespondence[email protected]

https://orcid.org/0000-0003-4262-0323 View further author information

Alessio Nocentinic Department of NEUROFARBA, Section of Pharmaceutical and Nutraceutical Sciences, University of Florence, Florence, ItalyView further author information

Andrea Brancaled Vysoká Škola Chemicko-Technologická v Praze, Prague, Czech RepublicView further author information

Carmine Varricchioh School of Pharmacy and Pharmaceutical Sciences, Cardiff University, Cardiff, UKView further author information

Roberta Bortolozzie Department of Woman’s and Child’s Health, Hemato-Oncology Lab, University of Padova, Padova, Italy;f Department of Pharmaceutical and Pharmacological Sciences, Section of Pharmacology, University of Padova, Padova, Italy;g Laboratory of Experimental Pharmacology, Istituto di Ricerca Pediatrica (IRP), Padova, ItalyView further author information

Lorenzo Manfredae Department of Woman’s and Child’s Health, Hemato-Oncology Lab, University of Padova, Padova, Italy;g Laboratory of Experimental Pharmacology, Istituto di Ricerca Pediatrica (IRP), Padova, ItalyView further author information

Giampietro Violae Department of Woman’s and Child’s Health, Hemato-Oncology Lab, University of Padova, Padova, Italy;g Laboratory of Experimental Pharmacology, Istituto di Ricerca Pediatrica (IRP), Padova, Italy

https://orcid.org/0000-0001-9329-165X View further author information

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Design, synthesis, and biological investigation of selective human carbonic anhydrase II, IX, and XII inhibitors using 7-aryl/heteroaryl triazolopyrimidines bearing a sulfanilamide scaffold

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Design, synthesis, and biological investigation of selective human carbonic anhydrase II, IX, and XII inhibitors using 7-aryl/heteroaryl triazolopyrimidines bearing a sulfanilamide scaffold

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