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Journal of Enzyme Inhibition and Medicinal Chemistry Volume 38, 2023 - Issue 1
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Research Article

A novel N-heterocycles substituted oseltamivir derivatives as potent inhibitors of influenza virus neuraminidase: discovery, synthesis and biological evaluation

Jiwei Zhanga Department of Medicinal Chemistry, Key Laboratory of Chemical Biology (Ministry of Education), School of Pharmaceutical Sciences, Cheeloo College of Medicine, Shandong University, Jinan, Shandong, P.R. China
,
Chuanfeng Liua Department of Medicinal Chemistry, Key Laboratory of Chemical Biology (Ministry of Education), School of Pharmaceutical Sciences, Cheeloo College of Medicine, Shandong University, Jinan, Shandong, P.R. China;b Suzhou Research Institute of Shandong University, Suzhou, Jiangsu, P.R. China
,
Ruifang Jiaa Department of Medicinal Chemistry, Key Laboratory of Chemical Biology (Ministry of Education), School of Pharmaceutical Sciences, Cheeloo College of Medicine, Shandong University, Jinan, Shandong, P.R. China
,
Xujie Zhanga Department of Medicinal Chemistry, Key Laboratory of Chemical Biology (Ministry of Education), School of Pharmaceutical Sciences, Cheeloo College of Medicine, Shandong University, Jinan, Shandong, P.R. China
,
Jian Zhangc Institute of Medical Sciences, The Second Hospital, Shandong University, Jinan, Shandong, P.R. China
,
Chiara Bertagnind Department of Molecular Medicine, University of Padova, Padova, Italy
,
Anna Bonominid Department of Molecular Medicine, University of Padova, Padova, Italy
,
Laura Guizzod Department of Molecular Medicine, University of Padova, Padova, Italy
,
Yuanmin Jianga Department of Medicinal Chemistry, Key Laboratory of Chemical Biology (Ministry of Education), School of Pharmaceutical Sciences, Cheeloo College of Medicine, Shandong University, Jinan, Shandong, P.R. China
,
Huinan Jiaa Department of Medicinal Chemistry, Key Laboratory of Chemical Biology (Ministry of Education), School of Pharmaceutical Sciences, Cheeloo College of Medicine, Shandong University, Jinan, Shandong, P.R. China
,
Shuzhen Jiaa Department of Medicinal Chemistry, Key Laboratory of Chemical Biology (Ministry of Education), School of Pharmaceutical Sciences, Cheeloo College of Medicine, Shandong University, Jinan, Shandong, P.R. China
,
Xiuli Mae Institute of Poultry Science, Shandong Academy of Agricultural Sciences, Jinan, Shandong, P.R. China
,
Arianna Loregiand Department of Molecular Medicine, University of Padova, Padova, Italy
,
Bing Huange Institute of Poultry Science, Shandong Academy of Agricultural Sciences, Jinan, Shandong, P.R. ChinaCorrespondence[email protected]
,
Peng Zhana Department of Medicinal Chemistry, Key Laboratory of Chemical Biology (Ministry of Education), School of Pharmaceutical Sciences, Cheeloo College of Medicine, Shandong University, Jinan, Shandong, P.R. China;f China-Belgium Collaborative Research Center for Innovative Antiviral Drugs of Shandong Province, Jinan, Shandong, PR ChinaCorrespondence[email protected]
&
Xinyong Liua Department of Medicinal Chemistry, Key Laboratory of Chemical Biology (Ministry of Education), School of Pharmaceutical Sciences, Cheeloo College of Medicine, Shandong University, Jinan, Shandong, P.R. China;f China-Belgium Collaborative Research Center for Innovative Antiviral Drugs of Shandong Province, Jinan, Shandong, PR ChinaCorrespondence[email protected]
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Article: 2277135 | Received 21 Apr 2023, Accepted 06 Oct 2023, Published online: 13 Nov 2023

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