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Research Article
New imidazole-2-thiones linked to acenaphythylenone as dual DNA intercalators and topoisomerase II inhibitors: structural optimization, docking, and apoptosis studies
Asmaa H. Mohameda Chemistry Department, Faculty of Science, Minia University, El-Minia, EgyptView further author information
, Mohammed B. Alshammarib Chemistry Department, College of Sciences and Humanities, Prince Sattam Bin Abdulaziz University, Al-Kharij, Saudi ArabiaCorrespondence[email protected]
https://orcid.org/0000-0001-9687-8747View further author information
, https://orcid.org/0000-0001-9687-8747View further author information
Ashraf A. Alya Chemistry Department, Faculty of Science, Minia University, El-Minia, EgyptCorrespondence[email protected] [email protected]
https://orcid.org/0000-0002-0314-3408View further author information
, https://orcid.org/0000-0002-0314-3408View further author information
Kamal U. Sadeka Chemistry Department, Faculty of Science, Minia University, El-Minia, EgyptView further author information
, Akil Ahmadb Chemistry Department, College of Sciences and Humanities, Prince Sattam Bin Abdulaziz University, Al-Kharij, Saudi ArabiaView further author information
, Eman A. Aziza Chemistry Department, Faculty of Science, Minia University, El-Minia, EgyptView further author information
, Amira F. El-Yazbic Department of Pharmaceutical Analytical Chemistry, Faculty of Pharmacy, Alexandria University, Alexandria, EgyptView further author information
, Eman J. El-Agroudyd Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Alexandria University, Alexandria, Egypthttps://orcid.org/0000-0003-1947-1227View further author information
& Marwa E. Abdelazizd Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Alexandria University, Alexandria, Egypthttps://orcid.org/0000-0002-8936-8172View further author information
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Article: 2311818
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Received 09 Aug 2023, Accepted 24 Jan 2024, Published online: 15 Mar 2024
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