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Expert Opinion on Drug Metabolism & Toxicology Volume 17, 2021 - Issue 6
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Original Research

Development and evaluation of a physiologically based pharmacokinetic model to predict carvedilol-paroxetine metabolic drug–drug interaction in healthy adults and its extrapolation to virtual chronic heart failure patients for dose optimization

Muhammad Fawad Rasoola Department of Pharmacy Practice, Bahauddin Zakariya University, Multan, PakistanCorrespondence[email protected]
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Stephanie Läerb Department of Clinical Pharmacy and Pharmacotherapy, Heinrich-Heine University, Düsseldorf, GermanyView further author information
Pages 717-724 | Received 10 Dec 2020, Accepted 20 Apr 2021, Published online: 04 May 2021

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