An IBD-associated pathobiont synergises with NSAID to promote colitis which is blocked by NLRP3 inflammasome and Caspase-8 inhibitors

Raminder Singha APC Microbiome Ireland, University College Cork, Cork, Ireland;b Department of Medicine, School of Medicine, University College Cork, Cork, Ireland

https://orcid.org/0000-0002-5348-4112 View further author information

Valerio Rossinia APC Microbiome Ireland, University College Cork, Cork, IrelandView further author information

Stephen R. Stockdalea APC Microbiome Ireland, University College Cork, Cork, IrelandView further author information

Gonzalo Saiz-Gonzaloa APC Microbiome Ireland, University College Cork, Cork, Ireland;b Department of Medicine, School of Medicine, University College Cork, Cork, Ireland;c School of Biochemistry and Cell Biology, University College Cork, Cork, IrelandView further author information

Naomi Hanrahana APC Microbiome Ireland, University College Cork, Cork, Ireland;b Department of Medicine, School of Medicine, University College Cork, Cork, Ireland;c School of Biochemistry and Cell Biology, University College Cork, Cork, IrelandView further author information

Tanya D’ Souzaa APC Microbiome Ireland, University College Cork, Cork, IrelandView further author information

Adam Clooneya APC Microbiome Ireland, University College Cork, Cork, IrelandView further author information

Lorraine A. Drapera APC Microbiome Ireland, University College Cork, Cork, IrelandView further author information

Colin Hilla APC Microbiome Ireland, University College Cork, Cork, Ireland;d School of Microbiology, University College Cork, Cork, IrelandView further author information

Ken Nallya APC Microbiome Ireland, University College Cork, Cork, Ireland;c School of Biochemistry and Cell Biology, University College Cork, Cork, IrelandView further author information

Fergus Shanahana APC Microbiome Ireland, University College Cork, Cork, IrelandView further author information

Stefan Andersson-Engelse Irish Photonics Integration Centre, Tyndall National Institute, Cork, Ireland;f Department of Physics, University College Cork, Cork, IrelandView further author information

Silvia Melgara APC Microbiome Ireland, University College Cork, Cork, IrelandCorrespondence[email protected]

https://orcid.org/0000-0001-7463-3343 View further author information

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An IBD-associated pathobiont synergises with NSAID to promote colitis which is blocked by NLRP3 inflammasome and Caspase-8 inhibitors

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An IBD-associated pathobiont synergises with NSAID to promote colitis which is blocked by NLRP3 inflammasome and Caspase-8 inhibitors

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