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Research Paper

Gut microbiota-driven metabolic alterations reveal gut–brain communication in Alzheimer’s disease model mice

Yijing Chena Chinese Academy of Sciences Key Laboratory of Brain Connectome and Manipulation, Shenzhen Key Laboratory of Translational Research for Brain Diseases, The Brain Cognition and Brain Disease Institute, Shenzhen Institute of Advanced Technology, Chinese Academy of Sciences, Shenzhen–Hong Kong Institute of Brain Science–Shenzhen Fundamental Research Institutions, Shenzhen, China;b Guangdong Provincial Key Laboratory of Brain Science, Disease and Drug Development, HKUST Shenzhen Research Institute, Shenzhen, ChinaView further author information

Yinhu Lia Chinese Academy of Sciences Key Laboratory of Brain Connectome and Manipulation, Shenzhen Key Laboratory of Translational Research for Brain Diseases, The Brain Cognition and Brain Disease Institute, Shenzhen Institute of Advanced Technology, Chinese Academy of Sciences, Shenzhen–Hong Kong Institute of Brain Science–Shenzhen Fundamental Research Institutions, Shenzhen, China;b Guangdong Provincial Key Laboratory of Brain Science, Disease and Drug Development, HKUST Shenzhen Research Institute, Shenzhen, ChinaView further author information

Yingying Fana Chinese Academy of Sciences Key Laboratory of Brain Connectome and Manipulation, Shenzhen Key Laboratory of Translational Research for Brain Diseases, The Brain Cognition and Brain Disease Institute, Shenzhen Institute of Advanced Technology, Chinese Academy of Sciences, Shenzhen–Hong Kong Institute of Brain Science–Shenzhen Fundamental Research Institutions, Shenzhen, China;b Guangdong Provincial Key Laboratory of Brain Science, Disease and Drug Development, HKUST Shenzhen Research Institute, Shenzhen, ChinaView further author information

Shuai Chena Chinese Academy of Sciences Key Laboratory of Brain Connectome and Manipulation, Shenzhen Key Laboratory of Translational Research for Brain Diseases, The Brain Cognition and Brain Disease Institute, Shenzhen Institute of Advanced Technology, Chinese Academy of Sciences, Shenzhen–Hong Kong Institute of Brain Science–Shenzhen Fundamental Research Institutions, Shenzhen, China;b Guangdong Provincial Key Laboratory of Brain Science, Disease and Drug Development, HKUST Shenzhen Research Institute, Shenzhen, ChinaView further author information

Li Chenc Department of Neurology, Shenzhen Children’s Hospital, Shenzhen, ChinaView further author information

Yuewen Chena Chinese Academy of Sciences Key Laboratory of Brain Connectome and Manipulation, Shenzhen Key Laboratory of Translational Research for Brain Diseases, The Brain Cognition and Brain Disease Institute, Shenzhen Institute of Advanced Technology, Chinese Academy of Sciences, Shenzhen–Hong Kong Institute of Brain Science–Shenzhen Fundamental Research Institutions, Shenzhen, China;b Guangdong Provincial Key Laboratory of Brain Science, Disease and Drug Development, HKUST Shenzhen Research Institute, Shenzhen, ChinaView further author information

Yu Chena Chinese Academy of Sciences Key Laboratory of Brain Connectome and Manipulation, Shenzhen Key Laboratory of Translational Research for Brain Diseases, The Brain Cognition and Brain Disease Institute, Shenzhen Institute of Advanced Technology, Chinese Academy of Sciences, Shenzhen–Hong Kong Institute of Brain Science–Shenzhen Fundamental Research Institutions, Shenzhen, China;b Guangdong Provincial Key Laboratory of Brain Science, Disease and Drug Development, HKUST Shenzhen Research Institute, Shenzhen, ChinaCorrespondence[email protected]
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Gut microbiota-driven metabolic alterations reveal gut–brain communication in Alzheimer’s disease model mice

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Supplementary Table 1.xlsx

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Supplementary Figure 5.tif

Supplementary Table 6.csv

Supplementary Figure 2.tif

Supplementary Figure 1.tif

Supplementary Table 4.xls

Supplementary Figure 6.tiff

Supplementary Table 3.xlsx

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Gut microbiota-driven metabolic alterations reveal gut–brain communication in Alzheimer’s disease model mice

Supplementary Figure 4.tif

Supplementary Table 2.xlsx

Supplementary Table 1.xlsx

Supplementary Table 5.csv

Supplementary Figure 5.tif

Supplementary Table 6.csv

Supplementary Figure 2.tif

Supplementary Figure 1.tif

Supplementary Table 4.xls

Supplementary Figure 6.tiff

Supplementary Table 3.xlsx

Supplementary Figure 3.tif

Supplementary Figure 7.tiff

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