Detailed gene dose analysis reveals recurrent focal gene deletions in pediatric B-cell precursor acute lymphoblastic leukemia

Ingegerd Ivanov ÖfverholmDepartment of Molecular Medicine and Surgery, Center for Molecular Medicine, Karolinska Institutet, Stockholm, Sweden; Correspondence[email protected]

Anh Nhi TranDepartment of Molecular Medicine and Surgery, Center for Molecular Medicine, Karolinska Institutet, Stockholm, Sweden;

Linda OlssonDivision of Clinical Genetics, Department of Laboratory Medicine, Lund University, Lund, Sweden;

Vasilios ZachariadisDepartment of Molecular Medicine and Surgery, Center for Molecular Medicine, Karolinska Institutet, Stockholm, Sweden;

Mats HeymanDepartment of Women’s and Children’s Health, Karolinska Institutet, Stockholm, Sweden;

Eva RuddDepartment of Molecular Medicine and Surgery, Center for Molecular Medicine, Karolinska Institutet, Stockholm, Sweden;

Elisabeth Syk LundbergDepartment of Molecular Medicine and Surgery, Center for Molecular Medicine, Karolinska Institutet, Stockholm, Sweden;

Magnus NordenskjöldDepartment of Molecular Medicine and Surgery, Center for Molecular Medicine, Karolinska Institutet, Stockholm, Sweden;

Bertil JohanssonDivision of Clinical Genetics, Department of Laboratory Medicine, Lund University, Lund, Sweden; ;Department of Clinical Genetics, University and Regional Laboratories, Region Skåne, Lund, Sweden

Ann NordgrenDepartment of Molecular Medicine and Surgery, Center for Molecular Medicine, Karolinska Institutet, Stockholm, Sweden;

Gisela BarbanyDepartment of Molecular Medicine and Surgery, Center for Molecular Medicine, Karolinska Institutet, Stockholm, Sweden;

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Detailed gene dose analysis reveals recurrent focal gene deletions in pediatric B-cell precursor acute lymphoblastic leukemia

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Supplementary Table. All subchromosomal CNAs in the cohort; Chr, chromosome; Mean Log R, mean log ratio; Affected gene/s, selected genes in CNA region with known or potential relevance in leukemia or other cancers.

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Detailed gene dose analysis reveals recurrent focal gene deletions in pediatric B-cell precursor acute lymphoblastic leukemia

ICMJE Forms for Disclosure of Potential Conflicts of Interest

Supplementary Table. All subchromosomal CNAs in the cohort; Chr, chromosome; Mean Log R, mean log ratio; Affected gene/s, selected genes in CNA region with known or potential relevance in leukemia or other cancers.

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