Summary
2005, Vol. 8, No. 3-4, Pages 135-140 , DOI 10.1080/13685530500277232

Frailty and the aging male

J. E. Morley1, M. J. Kim1, M. T. Haren1, R. Kevorkian1 and W. A. Banks1
1GRECC, VA Medical Center, Saint Louis University School of Medicine, Saint Louis, Missouri, USA
Correspondence: J. E. Morley, Division of Geriatric Medicine, Saint Louis University School of Medicine, 1402 S. Grand Boulevard, M238, Saint Louis, Missouri, 63104, USA



Frailty occurs in aging males for a variety of reasons. It is less common in males than females. Diseases which are particularly associated with frailty are diabetes mellitus, atherosclerosis, anemia and chronic obstructive pulmonary disease. Insulin resistance syndrome plays a pathogenetic role in the “fat-frail” syndrome. Sarcopenia occurs predominantly because of hormone deficiency and cytokine excess. Pain and anorexia are also associated with frailty. Stem cell research represents a potential promise for the treatment of frailty.

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Forward Links to Citing Articles

M. J. Kaiser, S. Bandinelli, B. Lunenfeld. (2009) The nutritional pattern of frailty – Proceedings from the 5th Italian Congress of Endocrinology of Aging, Parma, Italy, 27–28 March 2009. The Aging Male 12:4, 87-94
Online publication date: 1-Dec-2009.
Summary | Full Text | PDF (180 KB) | PDF Plus (181 KB) 
M. J. Kaiser, S. Bandinelli, B. Lunenfeld. The nutritional pattern of frailty – Proceedings from the 5th Italian Congress of Endocrinology of Aging, Parma, Italy, 27–28 March 2009. The Aging Male 0:0, 1-8
Summary | Full Text | PDF (180 KB) | PDF Plus (181 KB) 
John E. Morley. (2007) The diagnosis of late life hypogonadism. The Aging Male 10:4, 217-220
Online publication date: 1-Jan-2007.
Summary | Full Text | PDF (68 KB) | PDF Plus (87 KB) 
J. E. Morley, Director. (2006) Is weight loss harmful to older men?. The Aging Male 9:3, 135-137
Online publication date: 1-Jan-2006.
Citation | Full Text | PDF (301 KB) | PDF Plus (304 KB) 
 

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Authors:
J. E. Morley
M. J. Kim
M. T. Haren
R. Kevorkian
W. A. Banks
Keywords:
Sarcopenia
myostatin
IGF-1
testosterone
cytokines