Advances in Genomics and Genetics, Volume 4, Issue (2014)

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Advances in Genomics and Genetics, Volume 4, Issue (2014)

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Original Research

Article
Association between breast and thyroid cancers
Steven Lehrer, Sheryl Green, John A Martignetti & Kenneth E Rosenzweig
Pages: 1-4
Published online: 20 Feb 2014
AbstractforAssociation between breast and thyroid cancers | Full Text | References | PDF (188.4 KB)
  • 92 Views
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Open Access
Article
A preliminary case study of androgen receptor gene polymorphism association with impulsivity in women with alcoholism
Daniel J Mettman, Merlin G Butler, Albert B Poje, Elizabeth C Penick & Ann M Manzardo
Pages: 5-13
Published online: 03 Mar 2014
AbstractforA preliminary case study of androgen receptor gene polymorphism association with impulsivity in women with alcoholism | Full Text | References | PDF (374.8 KB)
  • 70 Views
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Open Access

Review

Review Article
Exome sequencing: what clinicians need to know
Leandro Sastre
Pages: 15-27
Published online: 29 Jan 2023
AbstractforExome sequencing: what clinicians need to know | Full Text | References | PDF (349.5 KB)
  • 205 Views
  • 1 CrossRef citations
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Open Access
Review Article
Oxidative stress at high altitude: genotype–phenotype correlations
Priyanka Pandey & MA Qadar Pasha
Pages: 29-43
Published online: 07 May 2014
AbstractforOxidative stress at high altitude: genotype–phenotype correlations | Full Text | References | PDF (2.4 MB)
  • 97 Views
  • 2 CrossRef citations
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Open Access
Review Article
Predictive value of genomics in the screening of type 2 diabetes: limitations and current status
V Radha & V Mohan
Pages: 45-57
Published online: 15 May 2014
AbstractforPredictive value of genomics in the screening of type 2 diabetes: limitations and current status | Full Text | References | PDF (487.1 KB)
  • 76 Views
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Open Access
Review Article
Genomic insights into the etiology of Alzheimer’s disease: a review
Christiane Reitz
Pages: 59-66
Published online: 29 May 2014
AbstractforGenomic insights into the etiology of Alzheimer’s disease: a review | Full Text | References | PDF (262.2 KB)
  • 121 Views
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Open Access
Review Article
Genomic and epigenetic instability in chordoma: current insights
Yong Feng, Jacson K Shen, Francis J Hornicek & Zhenfeng Duan
Pages: 67-78
Published online: 29 Jan 2023
AbstractforGenomic and epigenetic instability in chordoma: current insights | Full Text | References | PDF (1.2 MB)
  • 76 Views
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Open Access

Original Research

Article
Role of PTPN22 and VDR gene polymorphisms in susceptibility to rheumatoid arthritis: a study from central India
Smriti Shukla, Arvind Kumar Tripathi, Jitendra Kumar Tripathi, Manoj Indurkar & Ugam Kumari Chauhan
Pages: 79-85
Published online: 19 Jun 2014
AbstractforRole of PTPN22 and VDR gene polymorphisms in susceptibility to rheumatoid arthritis: a study from central India | Full Text | References | PDF (607.3 KB)
  • 78 Views
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Open Access
Article
Two different BRCA2 mutations found in a multigenerational family with a history of breast, prostate, and lung cancers
Diane A Caporale & Erica E Swenson
Pages: 87-94
Published online: 20 Jun 2014
AbstractforTwo different BRCA2 mutations found in a multigenerational family with a history of breast, prostate, and lung cancers | Full Text | References | PDF (1.5 MB)
  • 93 Views
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Open Access

Review

Review Article
Developments in the treatment of transfusion-dependent anemia in patients with myelodysplastic syndromes: epidemiology, etiology, genetics, and targeted therapies
Azra Raza, Nicholas Iverson & Abdullah M Ali
Pages: 95-106
Published online: 14 Jul 2014
AbstractforDevelopments in the treatment of transfusion-dependent anemia in patients with myelodysplastic syndromes: epidemiology, etiology, genetics, and targeted therapies | Full Text | References | PDF (1.2 MB)
  • 68 Views
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Open Access

Original Research

Article
Exonic deletion of OPHN1 resulting in seizures, intellectual disability, and brain malformations
Austin Larson, Jamie LeRoux & Ellen Roy Elias
Pages: 107-113
Published online: 14 Jul 2014
AbstractforExonic deletion of OPHN1 resulting in seizures, intellectual disability, and brain malformations | Full Text | References | PDF (1.6 MB)
  • 99 Views
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Open Access

Review

Review Article
Whole exome sequencing for cancer – is there evidence of clinical utility?
Alka Malhotra, Susan Levine & Diane Allingham-Hawkins
Pages: 115-128
Published online: 29 Jan 2023
AbstractforWhole exome sequencing for cancer – is there evidence of clinical utility? | Full Text | References | PDF (369.9 KB)
  • 113 Views
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Open Access
Review Article
Consequences of ongoing retrotransposition in mammalian genomes
Patrick H Maxwell
Pages: 129-142
Published online: 26 Sep 2014
AbstractforConsequences of ongoing retrotransposition in mammalian genomes | Full Text | References | PDF (639.3 KB)
  • 82 Views
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Open Access
Review Article
Insights into the genetic basis of systemic sclerosis: immunity in human disease and in mouse models
Minghua Wu & Maureen D Mayes
Pages: 143-151
Published online: 26 Sep 2014
AbstractforInsights into the genetic basis of systemic sclerosis: immunity in human disease and in mouse models | Full Text | References | PDF (278.2 KB)
  • 66 Views
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Open Access
Review Article
K-type human endogenous retroviral elements in human melanoma
Liliana Rincon, Michael P Sedrak, Huijian Sun, Gregorio Garza, Brent Kelly & Jianli Dong
Pages: 153-159
Published online: 29 Jan 2023
AbstractforK-type human endogenous retroviral elements in human melanoma | Full Text | References | PDF (961.1 KB)
  • 63 Views
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Open Access
Review Article
Cystic fibrosis gene mutations: evaluation and assessment of disease severity
Emilie Vallières & Joseph Stuart Elborn
Pages: 161-172
Published online: 29 Jan 2023
AbstractforCystic fibrosis gene mutations: evaluation and assessment of disease severity | Full Text | References | PDF (1.1 MB)
  • 786 Views
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Open Access
Review Article
Autosomal dominant polycystic kidney disease: genetics, epidemiology, and treatment
Berenice Reed-Gitomer
Pages: 173-183
Published online: 31 Oct 2014
AbstractforAutosomal dominant polycystic kidney disease: genetics, epidemiology, and treatment | Full Text | References | PDF (894 KB)
  • 94 Views
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Open Access
Review Article
Sumoylation in gene regulation and cardiac disease: potential for drug discovery
Ilimbek Beketaev & Jun Wang
Pages: 185-192
Published online: 29 Jan 2023
AbstractforSumoylation in gene regulation and cardiac disease: potential for drug discovery | Full Text | References | PDF (385.1 KB)
  • 63 Views
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Open Access
Review Article
Clinical significance and implications of genetic and genomic studies in patients with osteoarthritis
Ogechi Muoh, Charles J Malemud & Ali D Askari
Pages: 193-206
Published online: 10 Nov 2014
AbstractforClinical significance and implications of genetic and genomic studies in patients with osteoarthritis | Full Text | References | PDF (357 KB)
  • 73 Views
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Open Access

Original Research

Article
Multicentric osteolysis with nodulosis, arthritis, and cardiac defect syndrome: loss of MMP2 leads to increased apoptosis with alteration of apoptotic regulators and caspases and embryonic lethality
Rebecca A Mosig, Richard Schulz, Zamaneh Kassiri, Mitchell B Schaffler & John A Martignetti
Pages: 207-217
Published online: 13 Nov 2014
AbstractforMulticentric osteolysis with nodulosis, arthritis, and cardiac defect syndrome: loss of MMP2 leads to increased apoptosis with alteration of apoptotic regulators and caspases and embryonic lethality | Full Text | References | PDF (2.3 MB)
  • 74 Views
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Open Access

Review

Review Article
Future management of human obesity: understanding the meaning of genetic susceptibility
Arthur B Jenkins & Lesley V Campbell
Pages: 219-232
Published online: 29 Jan 2023
AbstractforFuture management of human obesity: understanding the meaning of genetic susceptibility | Full Text | References | PDF (366.4 KB)
  • 101 Views
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Open Access

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