Biologics: Targets and Therapy, Volume 15, Issue (2021)

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Biologics: Targets and Therapy, Volume 15, Issue (2021)

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Original Research

Article
Switching and Discontinuation Patterns Among Patients Stable on Originator Infliximab Who Switched to an Infliximab Biosimilar or Remained on Originator Infliximab
Timothy Fitzgerald, Richard Melsheimer, Marie-Hélène Lafeuille, Patrick Lefebvre, Laura Morrison, Kimberly Woodruff, Iris Lin & Bruno Emond
Pages: 1-15
Published online: 06 Jan 2021
AbstractforSwitching and Discontinuation Patterns Among Patients Stable on Originator Infliximab Who Switched to an Infliximab Biosimilar or Remained on Originator Infliximab | Full Text | References | PDF (6.8 MB) | EPUB
  • 165 Views
  • 6 CrossRef citations
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Open Access

Review

Review Article
Biologic Therapies for Giant Cell Arteritis
Robert Harrington, Shamma Ahmad Al Nokhatha & Richard Conway
Pages: 17-29
Published online: 06 Jan 2021
AbstractforBiologic Therapies for Giant Cell Arteritis | Full Text | References | PDF (2.9 MB) | EPUB
  • 221 Views
  • 6 CrossRef citations
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Open Access
Review Article
Convalescent Plasma for the Treatment of Severe COVID-19
Massimo Franchini & Giancarlo Maria Liumbruno
Pages: 31-38
Published online: 14 Nov 2022
AbstractforConvalescent Plasma for the Treatment of Severe COVID-19 | Full Text | References | PDF (296.2 KB) | EPUB
  • 132 Views
  • 6 CrossRef citations
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Open Access
Review Article
Biologic Treatments of Psoriasis: An Update for the Clinician
Nicholas D Brownstone, Julie Hong, Megan Mosca, Edward Hadeler, Wilson Liao, Tina Bhutani & John Koo
Pages: 39-51
Published online: 14 Nov 2022
AbstractforBiologic Treatments of Psoriasis: An Update for the Clinician | Full Text | References | PDF (2 MB) | EPUB
  • 1241 Views
  • 23 CrossRef citations
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Open Access
Review Article
Autologous Hematopoietic Stem Cell Transplantation (AHSCT): An Evolving Treatment Avenue in Multiple Sclerosis
Reihane Mohammadi, Alisam Aryan, Mir Davood Omrani, Sayyed Mohammad Hossein Ghaderian & Zahra Fazeli
Pages: 53-59
Published online: 02 Mar 2021
AbstractforAutologous Hematopoietic Stem Cell Transplantation (AHSCT): An Evolving Treatment Avenue in Multiple Sclerosis | Full Text | References | PDF (290.5 KB) | EPUB
  • 214 Views
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Open Access
Review Article
Glomerulonephritis in Two Patients with SpA Treated with TNF-α Blockers and a Review of the Literature
Constantina A Bounia, Eftichia N Theodoropoulou & Stamatic-Nick C Liossis
Pages: 61-66
Published online: 14 Nov 2022
AbstractforGlomerulonephritis in Two Patients with SpA Treated with TNF-α Blockers and a Review of the Literature | Full Text | References | PDF (476.2 KB) | EPUB
  • 112 Views
  • 2 CrossRef citations
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Open Access
Review Article
The Current Status of Gene Therapy for the Treatment of Cancer
Tafere Mulaw Belete
Pages: 67-77
Published online: 18 Mar 2021
AbstractforThe Current Status of Gene Therapy for the Treatment of Cancer | Full Text | References | PDF (1.8 MB) | EPUB
  • 2600 Views
  • 27 CrossRef citations
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Open Access
Review Article
Immunotherapeutics for Ebola Virus Disease: Hope on the Horizon
Kyle L O’Donnell & Andrea Marzi
Pages: 79-86
Published online: 18 Mar 2021
AbstractforImmunotherapeutics for Ebola Virus Disease: Hope on the Horizon | Full Text | References | PDF (1.2 MB) | EPUB
  • 218 Views
  • 5 CrossRef citations
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Open Access

Original Research

Article
Virus Neutralization by Human Intravenous Immunoglobulin Against Influenza Virus Subtypes A/H5 and A/H7
Ritsuko Kubota-Koketsu, Mikihiro Yunoki, Yoshinobu Okuno & Kazuyoshi Ikuta
Pages: 87-94
Published online: 14 Nov 2022
AbstractforVirus Neutralization by Human Intravenous Immunoglobulin Against Influenza Virus Subtypes A/H5 and A/H7 | Full Text | References | PDF (811.7 KB) | EPUB
  • 122 Views
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Open Access

Review

Review Article
Armored CAR T-Cells: The Next Chapter in T-Cell Cancer Immunotherapy
Elizabeth R Hawkins, Reena R D’Souza & Astero Klampatsa
Pages: 95-105
Published online: 14 Apr 2021
AbstractforArmored CAR T-Cells: The Next Chapter in T-Cell Cancer Immunotherapy | Full Text | References | PDF (2.2 MB) | EPUB
  • 548 Views
  • 16 CrossRef citations
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Open Access

Case Report

Case Report
Acrodermatitis Continua of Hallopeau Evolving into Generalized Pustular Psoriasis Following COVID‐19: A Case Report of a Successful Treatment with Infliximab in Combination with Acitretin
Dominik Samotij, Ewelina Gawron, Justyna Szczęch, Elżbieta Ostańska & Adam Reich
Pages: 107-113
Published online: 14 Nov 2022
AbstractforAcrodermatitis Continua of Hallopeau Evolving into Generalized Pustular Psoriasis Following COVID‐19: A Case Report of a Successful Treatment with Infliximab in Combination with Acitretin | Full Text | References | PDF (371.8 KB) | EPUB
  • 139 Views
  • 7 CrossRef citations
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Open Access

Review

Review Article
Baculoviruses in Gene Therapy and Personalized Medicine
Sabrina Schaly, Merry Ghebretatios & Satya Prakash
Pages: 115-132
Published online: 14 Nov 2022
AbstractforBaculoviruses in Gene Therapy and Personalized Medicine | Full Text | References | PDF (1.4 MB) | EPUB
  • 456 Views
  • 4 CrossRef citations
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Open Access
Review Article
Biological Therapies in Children and Adolescents with Severe Uncontrolled Asthma: A Practical Review
Martina Votto, Maria De Filippo, Amelia Licari, Alessia Marseglia, Mara De Amici & Gian Luigi Marseglia
Pages: 133-142
Published online: 14 Nov 2022
AbstractforBiological Therapies in Children and Adolescents with Severe Uncontrolled Asthma: A Practical Review | Full Text | References | PDF (351.6 KB) | EPUB
  • 252 Views
  • 7 CrossRef citations
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Open Access
Review Article
Neuropilin 1: A Novel Entry Factor for SARS-CoV-2 Infection and a Potential Therapeutic Target
Endeshaw Chekol Abebe, Teklie Mengie Ayele, Zelalem Tilahun Muche & Tadesse Asmamaw Dejenie
Pages: 143-152
Published online: 14 Nov 2022
AbstractforNeuropilin 1: A Novel Entry Factor for SARS-CoV-2 Infection and a Potential Therapeutic Target | Full Text | References | PDF (338.5 KB) | EPUB
  • 193 Views
  • 21 CrossRef citations
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Open Access
Review Article
Antibody Therapies for Large B-Cell Lymphoma
Mattia Novo, Elisa Santambrogio, Pio Manlio Mirko Frascione, Delia Rota-Scalabrini & Umberto Vitolo
Pages: 153-174
Published online: 18 May 2021
AbstractforAntibody Therapies for Large B-Cell Lymphoma | Full Text | References | PDF (1.4 MB) | EPUB
  • 205 Views
  • 0 CrossRef citations
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Open Access
Review Article
How Can We Engineer CAR T Cells to Overcome Resistance?
Maya Glover, Stephanie Avraamides & John Maher
Pages: 175-198
Published online: 14 Nov 2022
AbstractforHow Can We Engineer CAR T Cells to Overcome Resistance? | Full Text | References | PDF (2.1 MB) | EPUB
  • 236 Views
  • 4 CrossRef citations
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Open Access
Review Article
Current Applications and Future Perspectives of CRISPR-Cas9 for the Treatment of Lung Cancer
Markeshaw Tiruneh G/Medhin, Endeshaw Chekol Abebe, Tekeba Sisay, Nega Berhane, Tesfahun Bekele Snr & Tadesse Asmamaw Dejenie
Pages: 199-204
Published online: 14 Nov 2022
AbstractforCurrent Applications and Future Perspectives of CRISPR-Cas9 for the Treatment of Lung Cancer | Full Text | References | PDF (269.2 KB) | EPUB
  • 541 Views
  • 2 CrossRef citations
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Open Access
Review Article
Monoclonal Antibody Therapies for High Risk Neuroblastoma
Wayne L Furman
Pages: 205-219
Published online: 14 Nov 2022
AbstractforMonoclonal Antibody Therapies for High Risk Neuroblastoma | Full Text | References | PDF (2.4 MB) | EPUB
  • 301 Views
  • 1 CrossRef citations
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Open Access
Review Article
Recent Advances in the Treatment of Hemophilia: A Review
Emanuela Marchesini, Massimo Morfini & Leonard Valentino
Pages: 221-235
Published online: 15 Jun 2021
AbstractforRecent Advances in the Treatment of Hemophilia: A Review | Full Text | References | PDF (370.1 KB) | EPUB
  • 1502 Views
  • 12 CrossRef citations
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Open Access

Original Research

Article
An Australian Real-World Study of Treatment Persistence of Ustekinumab in Crohn’s Disease
Tzu Hsiang Chien, Andrea Puig, Thang Khuong, Mahsa H Kouhkamari, Samuel Che & Tom Hsun-Wei Huang
Pages: 237-245
Published online: 14 Nov 2022
AbstractforAn Australian Real-World Study of Treatment Persistence of Ustekinumab in Crohn’s Disease | Full Text | References | PDF (364.7 KB) | EPUB
  • 193 Views
  • 3 CrossRef citations
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Open Access

Review

Review Article
Latest Advances for the Treatment of Chronic Plaque Psoriasis with Biologics and Oral Small Molecules
Francesco Bellinato, Paolo Gisondi & Giampiero Girolomoni
Pages: 247-253
Published online: 14 Nov 2022
AbstractforLatest Advances for the Treatment of Chronic Plaque Psoriasis with Biologics and Oral Small Molecules | Full Text | References | PDF (320 KB) | EPUB
  • 486 Views
  • 13 CrossRef citations
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Open Access
Review Article
Using Monoclonal Antibody Therapies for Multiple Sclerosis: A Review
Paul M Elsbernd & Jonathan L Carter
Pages: 255-263
Published online: 30 Jun 2021
AbstractforUsing Monoclonal Antibody Therapies for Multiple Sclerosis: A Review | Full Text | References | PDF (252 KB) | EPUB
  • 265 Views
  • 3 CrossRef citations
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Open Access
Review Article
The Impact of NK Cell-Based Therapeutics for the Treatment of Lung Cancer for Biologics: Targets and Therapy
Gerhard Hamilton & Adelina Plangger
Pages: 265-277
Published online: 07 Jul 2021
AbstractforThe Impact of NK Cell-Based Therapeutics for the Treatment of Lung Cancer for Biologics: Targets and Therapy | Full Text | References | PDF (1.5 MB) | EPUB
  • 317 Views
  • 7 CrossRef citations
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Open Access

Original Research

Article
High Body Mass Index is Associated with Shorter Retention of Tumor Necrosis Factor-Alpha Blocker Treatment in Rheumatoid Arthritis
Ofir Elalouf, Merav Lidar, Tatiana Reitblat, Devy Zisman, Alexandra Balbir-Gurman, Odelia Hakakian, Tanya Mashiach, Ronit Almog & Ori Elkayam
Pages: 279-287
Published online: 20 Jul 2021
AbstractforHigh Body Mass Index is Associated with Shorter Retention of Tumor Necrosis Factor-Alpha Blocker Treatment in Rheumatoid Arthritis | Full Text | References | PDF (2 MB) | EPUB
  • 108 Views
  • 1 CrossRef citations
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Open Access
Article
Sensitivity Assessment of Wilms Tumor Gene (WT1) Expression in Glioblastoma using qPCR and Immunohistochemistry and its Association with IDH1 Mutation and Recurrence Interval
Maher Kurdi, Nadeem Shafique Butt, Saleh Baeesa, Abudukadeer Kuerban, Yazid Maghrabi, Anas Bardeesi, Rothaina Saeedi, Badrah S Alghamdi, Ahmed I Lary, Fawaz Mohamed & Sahar Hakamy
Pages: 289-297
Published online: 14 Nov 2022
AbstractforSensitivity Assessment of Wilms Tumor Gene (WT1) Expression in Glioblastoma using qPCR and Immunohistochemistry and its Association with IDH1 Mutation and Recurrence Interval | Full Text | References | PDF (5.2 MB) | EPUB
  • 143 Views
  • 0 CrossRef citations
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Open Access

Review

Review Article
Stem Cell Therapy for Retinal Degeneration: The Evidence to Date
Amit Sharma & Bithiah Grace Jaganathan
Pages: 299-306
Published online: 27 Jul 2021
AbstractforStem Cell Therapy for Retinal Degeneration: The Evidence to Date | Full Text | References | PDF (1.3 MB) | EPUB
  • 1033 Views
  • 10 CrossRef citations
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Open Access
Review Article
View Point: Disease Modification and Cell Secretome Based Approaches in Parkinson’s Disease: Are We on the Right Track?
Thomas Müller
Pages: 307-316
Published online: 29 Jul 2021
AbstractforView Point: Disease Modification and Cell Secretome Based Approaches in Parkinson’s Disease: Are We on the Right Track? | Full Text | References | PDF (939 KB) | EPUB
  • 106 Views
  • 0 CrossRef citations
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Open Access

Case Series

Case Report
Infliximab in Combination with Low-Dose Acitretin in Generalized Pustular Psoriasis: A Report of Two Cases and Review of the Literature
Marta Kołt-Kamińska, Magdalena Żychowska & Adam Reich
Pages: 317-327
Published online: 07 Aug 2021
AbstractforInfliximab in Combination with Low-Dose Acitretin in Generalized Pustular Psoriasis: A Report of Two Cases and Review of the Literature | Full Text | References | PDF (1.3 MB) | EPUB
  • 121 Views
  • 3 CrossRef citations
  • 0Altmetric
Open Access

Original Research

Article
HHLA2 Expression is Associated with Poor Survival in Patients with Hepatocellular Carcinoma
Yituo Xu, Zhijie Huang, Xingjuan Yu, Zhixiong Li, Limin Zheng & Jing Xu
Pages: 329-341
Published online: 13 Aug 2021
AbstractforHHLA2 Expression is Associated with Poor Survival in Patients with Hepatocellular Carcinoma | Full Text | References | PDF (8 MB) | EPUB
  • 125 Views
  • 2 CrossRef citations
  • 0Altmetric
Open Access

Review

Review Article
Biological Therapies for Rheumatoid Arthritis: An Overview for the Clinician
Kate E Findeisen, Julia Sewell & Andrew J K Ostor
Pages: 343-352
Published online: 12 Aug 2021
AbstractforBiological Therapies for Rheumatoid Arthritis: An Overview for the Clinician | Full Text | References | PDF (379.1 KB) | EPUB
  • 556 Views
  • 7 CrossRef citations
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Open Access
Review Article
Mechanism and Applications of CRISPR/Cas-9-Mediated Genome Editing
Misganaw Asmamaw & Belay Zawdie
Pages: 353-361
Published online: 21 Aug 2021
AbstractforMechanism and Applications of CRISPR/Cas-9-Mediated Genome Editing | Full Text | References | PDF (353.5 KB) | EPUB
  • 6717 Views
  • 34 CrossRef citations
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Open Access
Review Article
An Overview of the Safety and Efficacy of Monoclonal Antibodies for the Chronic Obstructive Pulmonary Disease
Mario Cazzola, Josuel Ora, Francesco Cavalli, Paola Rogliani & Maria Gabriella Matera
Pages: 363-374
Published online: 14 Nov 2022
AbstractforAn Overview of the Safety and Efficacy of Monoclonal Antibodies for the Chronic Obstructive Pulmonary Disease | Full Text | References | PDF (420.9 KB) | EPUB
  • 318 Views
  • 4 CrossRef citations
  • 0Altmetric
Open Access

Case Report

Case Report
Adalimumab Therapy in a Patient with Psoriasis, Down Syndrome, and Concomitant Hepatitis B Virus Infection
Abdulaziz Madani & Qais Almuhaideb
Pages: 375-378
Published online: 14 Nov 2022
AbstractforAdalimumab Therapy in a Patient with Psoriasis, Down Syndrome, and Concomitant Hepatitis B Virus Infection | Full Text | References | PDF (419.4 KB) | EPUB
  • 141 Views
  • 0 CrossRef citations
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Open Access

Review

Review Article
Stem Cell Therapy for Burns: Story so Far
Najath Abdul Kareem, Ayesha Aijaz & Marc G Jeschke
Pages: 379-397
Published online: 14 Nov 2022
AbstractforStem Cell Therapy for Burns: Story so Far | Full Text | References | PDF (6.2 MB) | EPUB
  • 769 Views
  • 6 CrossRef citations
  • 0Altmetric
Open Access
Review Article
Immunotherapeutic Advances for NSCLC
Marco Massafra, Maria Ilenia Passalacqua, Vittorio Gebbia, Paolo Macrì, Chiara Lazzari, Vanesa Gregorc, Carmelo Buda, Giuseppe Altavilla & Mariacarmela Santarpia
Pages: 399-417
Published online: 08 Oct 2021
AbstractforImmunotherapeutic Advances for NSCLC | Full Text | References | PDF (1.6 MB) | EPUB
  • 814 Views
  • 2 CrossRef citations
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Open Access
Review Article
Emerging Monoclonal Antibody Therapy for the Treatment of Acute Lymphoblastic Leukemia
Tareq Abuasab, Jacob Rowe & Ariella Tvito
Pages: 419-431
Published online: 14 Nov 2022
AbstractforEmerging Monoclonal Antibody Therapy for the Treatment of Acute Lymphoblastic Leukemia | Full Text | References | PDF (5.4 MB) | EPUB
  • 142 Views
  • 1 CrossRef citations
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Open Access

Original Research

Article
Certolizumab Can Also Be Effective in Monotherapy for the Treatment of Rheumatoid Arthritis Patients
Pedro Santos-Moreno, Susan Martinez, Linda Ibatá, Laura Villarreal, Manuel Rivero & Adriana Rojas-Villarraga
Pages: 433-440
Published online: 22 Oct 2021
AbstractforCertolizumab Can Also Be Effective in Monotherapy for the Treatment of Rheumatoid Arthritis Patients | Full Text | References | PDF (374 KB) | EPUB
  • 123 Views
  • 1 CrossRef citations
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Open Access

Review

Review Article
Biological Therapeutic Advances for the Treatment of Advanced Urothelial Cancers
Mimma Rizzo, Patrizia Giannatempo & Camillo Porta
Pages: 441-450
Published online: 14 Nov 2022
AbstractforBiological Therapeutic Advances for the Treatment of Advanced Urothelial Cancers | Full Text | References | PDF (343.4 KB) | EPUB
  • 95 Views
  • 1 CrossRef citations
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Open Access
Review Article
State-of-the-Art of Monoclonal Antibodies for the Treatment of Gastric Cancer
Debora Basile, Francesca Simionato, Alessandro Cappetta, Silvio Ken Garattini, Giandomenico Roviello & Giuseppe Aprile
Pages: 451-462
Published online: 14 Nov 2022
AbstractforState-of-the-Art of Monoclonal Antibodies for the Treatment of Gastric Cancer | Full Text | References | PDF (424.1 KB) | EPUB
  • 153 Views
  • 1 CrossRef citations
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Open Access

Original Research

Article
Treatment with Ixekizumab Following Secukinumab Failure in Patients with Psoriatic Arthritis: Real-Life Experience from a Resistant Population
Julia Berman, Victoria Furer, Mark Berman, Ofer Isakov, Devy Zisman, Amir Haddad & Ori Elkayam
Pages: 463-470
Published online: 14 Nov 2022
AbstractforTreatment with Ixekizumab Following Secukinumab Failure in Patients with Psoriatic Arthritis: Real-Life Experience from a Resistant Population | Full Text | References | PDF (2.2 MB) | EPUB
  • 194 Views
  • 2 CrossRef citations
  • 0Altmetric
Open Access

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