Cancer Management and Research, Volume 11, Issue (2019)

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Cancer Management and Research, Volume 11, Issue (2019)

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Original Research

Article
The construction and analysis of ceRNA networks in invasive breast cancer: a study based on The Cancer Genome Atlas
Chundi Gao, Huayao Li, Jing Zhuang, HongXiu Zhang, Kejia Wang, Jing Yang, Cun Liu, Lijuan Liu, Chao Zhou & Changgang Sun
Pages: 1-11
Published online: 17 Dec 2018
AbstractforThe construction and analysis of ceRNA networks in invasive breast cancer: a study based on The Cancer Genome Atlas | Full Text | References | PDF (6.6 MB) | EPUB
  • 187 Views
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Open Access
Article
miR-29a-3p inhibits growth, proliferation, and invasion of papillary thyroid carcinoma by suppressing NF-κB signaling via direct targeting of OTUB2
Yanfei Ma & Yu Sun
Pages: 13-23
Published online: 17 Dec 2018
AbstractformiR-29a-3p inhibits growth, proliferation, and invasion of papillary thyroid carcinoma by suppressing NF-κB signaling via direct targeting of OTUB2 | Full Text | References | PDF (5.1 MB) | EPUB
  • 123 Views
  • 35 CrossRef citations
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Open Access
Article
Low periostin expression predicts poor survival in intestinal type gastric cancer patients
Teming Zhang, Zheng Han, Arvine Chandoo, Xincheng Huang, Xiangwei Sun, Lele Ye, Changyuan Hu, Xiangyang Xue, Yingpeng Huang, Xian Shen, Wenjun Chang & Xiaoming Lin
Pages: 25-36
Published online: 18 Dec 2018
AbstractforLow periostin expression predicts poor survival in intestinal type gastric cancer patients | Full Text | References | PDF (2.1 MB) | EPUB
  • 70 Views
  • 6 CrossRef citations
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Open Access

Review

Review Article
The history of cancer pain and bone-targeted agents: 10 most commonly asked questions
Cláudia Margarida Pereira Vieira, Maria Fragoso, Marta Ferreira, Filipa Ferreira Pereira, Deolinda Pereira & Rui Medeiros
Pages: 37-46
Published online: 18 Dec 2018
AbstractforThe history of cancer pain and bone-targeted agents: 10 most commonly asked questions | Full Text | References | PDF (185.5 KB) | EPUB
  • 94 Views
  • 1 CrossRef citations
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Open Access

Original Research

Article
Pristimerin protects against doxorubicin-induced cardiotoxicity and fibrosis through modulation of Nrf2 and MAPK/NF-kB signaling pathways
Dina S El-Agamy, Khaled M El-Harbi, Saad Khoshhal, Nishat Ahmed, Mohamed A Elkablawy, Ahmed A Shaaban & Hany M Abo-Haded
Pages: 47-61
Published online: 19 Dec 2018
AbstractforPristimerin protects against doxorubicin-induced cardiotoxicity and fibrosis through modulation of Nrf2 and MAPK/NF-kB signaling pathways | Full Text | References | PDF (3.9 MB) | EPUB
  • 235 Views
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Open Access
Article
Aspartate aminotransferase-to-platelet ratio index predicts prognosis of hepatocellular carcinoma after postoperative adjuvant transarterial chemoembolization
Gui-Qi Zhu, Kang Wang, Biao Wang, Yu-Jie Zhou, Yi Yang, Er-Bao Chen, Zheng-Jun Zhou, Shao-Lai Zhou, Ying-Hong Shi, Jian Zhou & Zhi Dai
Pages: 63-79
Published online: 20 Dec 2018
AbstractforAspartate aminotransferase-to-platelet ratio index predicts prognosis of hepatocellular carcinoma after postoperative adjuvant transarterial chemoembolization | Full Text | References | PDF (1.2 MB) | EPUB
  • 68 Views
  • 10 CrossRef citations
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Open Access
Article
Chronic cadmium exposure aggravates malignant phenotypes of nasopharyngeal carcinoma by activating the Wnt/β-catenin signaling pathway via hypermethylation of the casein kinase 1α promoter
Lin Peng, Yi-Teng Huang, Fan Zhang, Jiong-Yu Chen & Xia Huo
Pages: 81-93
Published online: 19 Dec 2018
AbstractforChronic cadmium exposure aggravates malignant phenotypes of nasopharyngeal carcinoma by activating the Wnt/β-catenin signaling pathway via hypermethylation of the casein kinase 1α promoter | Full Text | References | PDF (6.8 MB) | EPUB
  • 83 Views
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Open Access
Article
Deguelin induces apoptosis in colorectal cancer cells by activating the p38 MAPK pathway
Liubo Chen, Kai Jiang, Haiyan Chen, Yang Tang, Xinyi Zhou, Yinuo Tan, Ying Yuan, Qian Xiao & Kefeng Ding
Pages: 95-105
Published online: 20 Dec 2018
AbstractforDeguelin induces apoptosis in colorectal cancer cells by activating the p38 MAPK pathway | Full Text | References | PDF (4 MB) | EPUB
  • 103 Views
  • 21 CrossRef citations
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Open Access
Article
Importance of avoiding surgery delays after initial discovery of suspected non-small-cell lung cancer in clinical stage IA patients
Hiroaki Kuroda, Yusuke Sugita, Yuko Ohya, Tatsuya Yoshida, Takaaki Arimura, Noriaki Sakakura, Toyoaki Hida, Yasushi Yatabe & Yukinori Sakao
Pages: 107-115
Published online: 20 Dec 2018
AbstractforImportance of avoiding surgery delays after initial discovery of suspected non-small-cell lung cancer in clinical stage IA patients | Full Text | References | PDF (422.5 KB) | EPUB
  • 71 Views
  • 3 CrossRef citations
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Open Access
Article
Evidence mapping and quality assessment of systematic reviews on therapeutic interventions for oral cancer
Meisser Madera Anaya, Juan Victor Ariel Franco, Mónica Ballesteros, Ivan Solà, Gerard Urrútia Cuchí & Xavier Bonfill Cosp
Pages: 117-130
Published online: 24 Dec 2018
AbstractforEvidence mapping and quality assessment of systematic reviews on therapeutic interventions for oral cancer | Full Text | References | PDF (2.3 MB) | EPUB
  • 144 Views
  • 20 CrossRef citations
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Open Access
Article
A six-mRNA prognostic model to predict survival in head and neck squamous cell carcinoma
Saisai Tian, Guofeng Meng & Weidong Zhang
Pages: 131-142
Published online: 20 Dec 2018
AbstractforA six-mRNA prognostic model to predict survival in head and neck squamous cell carcinoma | Full Text | References | PDF (2.2 MB) | EPUB
  • 59 Views
  • 26 CrossRef citations
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Open Access
Article
Knockdown of nucleophosmin 1 suppresses proliferation of triple-negative breast cancer cells through activating CDH1/Skp2/p27kip1 pathway
De Zeng, Yingsheng Xiao, Jianling Zhu, Chunyan Peng, Weiquan Liang & Haoyu Lin
Pages: 143-156
Published online: 21 Dec 2018
AbstractforKnockdown of nucleophosmin 1 suppresses proliferation of triple-negative breast cancer cells through activating CDH1/Skp2/p27kip1 pathway | Full Text | References | PDF (6.8 MB) | EPUB
  • 117 Views
  • 16 CrossRef citations
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Open Access
Article
Incidences and oncological outcomes of urothelial carcinoma in kidney transplant recipients
Jiwoong Yu, Chung Un Lee, Minyong Kang, Hwang Gyun Jeon, Byong Chang Jeong, Seong Il Seo, Seong Soo Jeon, Hyun Moo Lee & Hyun Hwan Sung
Pages: 157-166
Published online: 24 Dec 2018
AbstractforIncidences and oncological outcomes of urothelial carcinoma in kidney transplant recipients | Full Text | References | PDF (426.4 KB) | EPUB
  • 81 Views
  • 14 CrossRef citations
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Open Access

Review

Review Article
Radiation-induced skin reactions: mechanism and treatment
Jinlong Wei, Lingbin Meng, Xue Hou, Chao Qu, Bin Wang, Ying Xin & Xin Jiang
Pages: 167-177
Published online: 21 Dec 2018
AbstractforRadiation-induced skin reactions: mechanism and treatment | Full Text | References | PDF (642.9 KB) | EPUB
  • 909 Views
  • 99 CrossRef citations
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Open Access

Original Research

Article
Transcriptomic analyses identify key differentially expressed genes and clinical outcomes between triple-negative and non-triple-negative breast cancer
Bo Chen, Hailin Tang, Xi Chen, Guochun Zhang, Yulei Wang, Xiaoming Xie & Ning Liao
Pages: 179-190
Published online: 21 Dec 2018
AbstractforTranscriptomic analyses identify key differentially expressed genes and clinical outcomes between triple-negative and non-triple-negative breast cancer | Full Text | References | PDF (1.6 MB) | EPUB
  • 180 Views
  • 33 CrossRef citations
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Open Access
Article
Association of markers of systemic and local inflammation with prognosis of patients with rectal cancer who received neoadjuvant radiotherapy
Xueqing Zhang, Jinluan Li, Qingqin Peng, Yunxia Huang, Lirui Tang, Qingyang Zhuang, Feifei Lin, Xijin Lin, Kaixin Du & Junxin Wu
Pages: 191-199
Published online: 24 Dec 2018
AbstractforAssociation of markers of systemic and local inflammation with prognosis of patients with rectal cancer who received neoadjuvant radiotherapy | Full Text | References | PDF (489 KB) | EPUB
  • 92 Views
  • 16 CrossRef citations
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Open Access
Article
MARCH5 overexpression contributes to tumor growth and metastasis and associates with poor survival in breast cancer
Haili Tang, Shujia Peng, Yanming Dong, Xiaojun Yang, Ping Yang, Lin Yang, Bing Yang & Guoqiang Bao
Pages: 201-215
Published online: 24 Dec 2018
AbstractforMARCH5 overexpression contributes to tumor growth and metastasis and associates with poor survival in breast cancer | Full Text | References | PDF (9.6 MB) | EPUB
  • 79 Views
  • 16 CrossRef citations
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Open Access
Article
Potential therapeutic value of primary tumor resection in ampullary cancer patients with distant metastases at initial diagnosis: a population-based study
Jie Wang, Xiaobo Bo, Pinxiang Lu, Tao Suo, Xiaoling Ni, Han Liu, Hongtao Pan, Sheng Shen, Min Li, Dexiang Zhang, Yueqi Wang & Houbao Liu
Pages: 217-228
Published online: 24 Dec 2018
AbstractforPotential therapeutic value of primary tumor resection in ampullary cancer patients with distant metastases at initial diagnosis: a population-based study | Full Text | References | PDF (1.5 MB) | EPUB
  • 58 Views
  • 0 CrossRef citations
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Open Access
Article
Prognostic value of the Glasgow prognostic score in colorectal cancer: a meta-analysis of 9,839 patients
Xin Lu, Wanying Guo, Wei Xu, Xuelei Zhang, Zhijie Shi, Leizhen Zheng & Wenzhao Zhao
Pages: 229-249
Published online: 24 Dec 2018
AbstractforPrognostic value of the Glasgow prognostic score in colorectal cancer: a meta-analysis of 9,839 patients | Full Text | References | PDF (1.8 MB) | EPUB
  • 109 Views
  • 44 CrossRef citations
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Open Access
Article
Overexpression of PDK4 is associated with cell proliferation, drug resistance and poor prognosis in ovarian cancer
Jinghao Wang, Yu Qian & Meiyan Gao
Pages: 251-262
Published online: 24 Dec 2018
AbstractforOverexpression of PDK4 is associated with cell proliferation, drug resistance and poor prognosis in ovarian cancer | Full Text | References | PDF (4.6 MB) | EPUB
  • 128 Views
  • 33 CrossRef citations
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Open Access
Article
Higher plasma concentration of TP53-induced glycolysis and apoptosis regulator is associated with a lower risk of colorectal cancer metastasis
Lin Lin, Yanjun Mi, Xun Li, Cuixin Peng, Zhaoshui Shangguan, Zhibin Li & Suhuan Liu
Pages: 263-272
Published online: 24 Dec 2018
AbstractforHigher plasma concentration of TP53-induced glycolysis and apoptosis regulator is associated with a lower risk of colorectal cancer metastasis | Full Text | References | PDF (1.1 MB) | EPUB
  • 77 Views
  • 1 CrossRef citations
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Open Access
Article
Importance of gene expression signatures in pancreatic cancer prognosis and the establishment of a prediction model
Xiaokai Yan, Haifeng Wan, Xiangyong Hao, Tian Lan, Wei Li, Lin Xu, Kefei Yuan & Hong Wu
Pages: 273-283
Published online: 27 Dec 2018
AbstractforImportance of gene expression signatures in pancreatic cancer prognosis and the establishment of a prediction model | Full Text | References | PDF (3 MB) | EPUB
  • 169 Views
  • 36 CrossRef citations
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Open Access
Article
Polymorphisms in DNA repair pathway genes and ABCG2 gene in advanced colorectal cancer: correlation with tumor characteristics and clinical outcome in oxaliplatin-based chemotherapy
Xiaoyun Hu, Wenyan Qin, Shanqiong Li, Miao He, Yilin Wang, Shu Guan, Haishan Zhao, Weifan Yao, Minjie Wei, Mingyan Liu & Huizhe Wu
Pages: 285-297
Published online: 27 Dec 2018
AbstractforPolymorphisms in DNA repair pathway genes and ABCG2 gene in advanced colorectal cancer: correlation with tumor characteristics and clinical outcome in oxaliplatin-based chemotherapy | Full Text | References | PDF (1.3 MB) | EPUB
  • 76 Views
  • 12 CrossRef citations
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Open Access
Article
Switching to anastrozole plus goserelin vs continued tamoxifen for adjuvant therapy of premenopausal early-stage breast cancer: preliminary results from a randomized trial
Jian-wei Li, Guang-yu Liu, Ya-jie Ji, Xia Yan, Da Pang, Ze-fei Jiang, De-dian Chen, Bin Zhang, Bing-he Xu & Zhi-ming Shao
Pages: 299-307
Published online: 27 Dec 2018
AbstractforSwitching to anastrozole plus goserelin vs continued tamoxifen for adjuvant therapy of premenopausal early-stage breast cancer: preliminary results from a randomized trial | Full Text | References | PDF (238.4 KB) | EPUB
  • 104 Views
  • 8 CrossRef citations
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Open Access
Article
Sex-related differences in urothelial cell carcinoma of the bladder in Germany
Thomas Scheller, Rainer Hofmann & Axel Hegele
Pages: 309-316
Published online: 28 Dec 2018
AbstractforSex-related differences in urothelial cell carcinoma of the bladder in Germany | Full Text | References | PDF (1.6 MB) | EPUB
  • 75 Views
  • 4 CrossRef citations
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Open Access
Article
Long-term survival after percutaneous irreversible electroporation of inoperable colorectal liver metastases
Andreas Schicho, Christoph Niessen, Michael Haimerl, Isabel Wiesinger, Christian Stroszczynski, Lukas P Beyer & Philipp Wiggermann
Pages: 317-322
Published online: 27 Dec 2018
AbstractforLong-term survival after percutaneous irreversible electroporation of inoperable colorectal liver metastases | Full Text | References | PDF (563.2 KB) | EPUB
  • 62 Views
  • 19 CrossRef citations
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Open Access
Article
Identification of hub genes and outcome in colon cancer based on bioinformatics analysis
Wanli Yang, Jiaojiao Ma, Wei Zhou, Zichao Li, Xin Zhou, Bo Cao, Yujie Zhang, Jinqiang Liu, Zhiping Yang, Hongwei Zhang, Qingchuan Zhao, Liu Hong & Daiming Fan
Pages: 323-338
Published online: 27 Dec 2018
AbstractforIdentification of hub genes and outcome in colon cancer based on bioinformatics analysis | Full Text | References | PDF (5.9 MB) | EPUB
  • 406 Views
  • 24 CrossRef citations
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Open Access
Article
Surgery of primary tumor improves the survival of newly diagnosed metastatic melanoma: a population-based, propensity-matched study
Dongxiao Zhang, Yinjun Dong, Xiubin Sun, Shuanghu Yuan & Jinming Yu
Pages: 339-346
Published online: 27 Dec 2018
AbstractforSurgery of primary tumor improves the survival of newly diagnosed metastatic melanoma: a population-based, propensity-matched study | Full Text | References | PDF (727.9 KB) | EPUB
  • 84 Views
  • 3 CrossRef citations
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Open Access
Article
Robust analysis of novel mRNA–lncRNA cross talk based on ceRNA hypothesis uncovers carcinogenic mechanism and promotes diagnostic accuracy in esophageal cancer
Li-Ping Chen, Hong Wang, Yi Zhang, Qiu-Xiang Chen, Tie-Su Lin, Zong-Qin Liu & Yang-Yang Zhou
Pages: 347-358
Published online: 27 Dec 2018
AbstractforRobust analysis of novel mRNA–lncRNA cross talk based on ceRNA hypothesis uncovers carcinogenic mechanism and promotes diagnostic accuracy in esophageal cancer | Full Text | References | PDF (2 MB) | EPUB
  • 101 Views
  • 12 CrossRef citations
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Open Access
Article
Sequential therapy with bevacizumab and EGFR inhibitors for metastatic colorectal carcinoma: a national registry-based analysis
Tomas Buchler, Renata Chloupkova, Alexandr Poprach, Ondrej Fiala, Igor Kiss, Katerina Kopeckova, Ladislav Dusek, Veronika Veskrnova, Lubomir Slavicek, Milan Kohoutek, Jindrich Finek, Marek Svoboda, Lubos Petruzelka & Bohuslav Melichar
Pages: 359-368
Published online: 28 Dec 2018
AbstractforSequential therapy with bevacizumab and EGFR inhibitors for metastatic colorectal carcinoma: a national registry-based analysis | Full Text | References | PDF (261.4 KB) | EPUB
  • 65 Views
  • 7 CrossRef citations
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Open Access
Article
IRF1 inhibits the proliferation and metastasis of colorectal cancer by suppressing the RAS-RAC1 pathway
Min Hong, Zuoyang Zhang, Qing Chen, Yanxia Lu, Jianming Zhang, Chun Lin, Fan Zhang, Wenjuan Zhang, Xiaomin Li, Wei Zhang & Xuenong Li
Pages: 369-378
Published online: 31 Dec 2018
AbstractforIRF1 inhibits the proliferation and metastasis of colorectal cancer by suppressing the RAS-RAC1 pathway | Full Text | References | PDF (5.2 MB) | EPUB
  • 104 Views
  • 25 CrossRef citations
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Open Access

Review

Review Article
Biliary tract cancer: current challenges and future prospects
Michele Ghidini, Claudio Pizzo, Andrea Botticelli, Jens Claus Hahne, Rodolfo Passalacqua, Gianluca Tomasello & Fausto Petrelli
Pages: 379-388
Published online: 28 Dec 2018
AbstractforBiliary tract cancer: current challenges and future prospects | Full Text | References | PDF (690.4 KB) | EPUB
  • 205 Views
  • 36 CrossRef citations
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Open Access

Original Research

Article
RETRACTED ARTICLE: OCT4 accelerates tumorigenesis through activating JAK/STAT signaling in ovarian cancer side population cells
Zhengyi Ruan, Xingyu Yang & Weiwei Cheng
Pages: 389-399
Published online: 28 Dec 2018
AbstractforRETRACTED ARTICLE: OCT4 accelerates tumorigenesis through activating JAK/STAT signaling in ovarian cancer side population cells | PDF (2.7 MB)
  • 94 Views
  • 39 CrossRef citations
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Open Access
Article
Helical tomotherapy in patients with leptomeningeal metastases
Sanziana RI Schiopu, Gregor Habl, Matthias Haefner, Sonja Katayama, Klaus Herfarth, Juergen Debus & Florian Sterzing
Pages: 401-409
Published online: 31 Dec 2018
AbstractforHelical tomotherapy in patients with leptomeningeal metastases | Full Text | References | PDF (944.9 KB) | EPUB
  • 77 Views
  • 10 CrossRef citations
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Open Access
Article
Intraoperative monitoring of pelvic autonomic nerves during laparoscopic low anterior resection of rectal cancer
Min-Wei Zhou, Xiao-Yun Huang, Zong-You Chen, Zhen-Yang Li, Yi-Ming Zhou, Yi Yang, Zi-Hao Wang, Jian-Bin Xiang & Xiao-Dong Gu
Pages: 411-417
Published online: 31 Dec 2018
AbstractforIntraoperative monitoring of pelvic autonomic nerves during laparoscopic low anterior resection of rectal cancer | Full Text | References | PDF (1.3 MB) | EPUB
  • 98 Views
  • 11 CrossRef citations
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Open Access
Article
Identification of key genes and specific pathways potentially involved in androgen-independent, mitoxantrone-resistant prostate cancer
Sha Zhu, Lili Jiang, Liuyan Wang, Lingli Wang, Cong Zhang, Yu Ma & Tao Huang
Pages: 419-430
Published online: 03 Jan 2019
AbstractforIdentification of key genes and specific pathways potentially involved in androgen-independent, mitoxantrone-resistant prostate cancer | Full Text | References | PDF (3.2 MB) | EPUB
  • 100 Views
  • 4 CrossRef citations
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Open Access
Article
A nomogram for endoscopic screening in a high esophageal squamous cell cancer risk area: results from a population-based study
Jie Xing, Li Min, Hao Zhang, Peng Li, Wei Li, Fujin Lv, Yongjun Wang, Zheng Zhang, Hengcun Li, Qingdong Guo, Siyi Wang, Yu Zhao, Junmin Wang, Xiaoyan Shi, Anxin Wang, Shengtao Zhu, Ming Ji, Yongdong Wu, Shutian Zhang & On behalf of the NCECS Study Group
Pages: 431-442
Published online: 03 Jan 2019
AbstractforA nomogram for endoscopic screening in a high esophageal squamous cell cancer risk area: results from a population-based study | Full Text | References | PDF (2.2 MB) | EPUB
  • 68 Views
  • 5 CrossRef citations
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Open Access
Article
A circular RNA hsa_circ_0079929 inhibits tumor growth in hepatocellular carcinoma
Huifei Zheng, Tengfei Chen, Chang Li, Chun Xu, Cheng Ding, Jun Chen, Sheng Ju, Zhiwei Zhang, Zhipan Liang, Zihan Cui & Jun Zhao
Pages: 443-454
Published online: 03 Jan 2019
AbstractforA circular RNA hsa_circ_0079929 inhibits tumor growth in hepatocellular carcinoma | Full Text | References | PDF (7.6 MB) | EPUB
  • 95 Views
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Open Access
Article
NIMA-related kinase 2 overexpression is associated with poor survival in cancer patients: a systematic review and meta-analysis
Yang Yao, Jie Su, Lei Zhao, Na Luo, Lihui Long & Xingmei Zhu
Pages: 455-465
Published online: 03 Jan 2019
AbstractforNIMA-related kinase 2 overexpression is associated with poor survival in cancer patients: a systematic review and meta-analysis | Full Text | References | PDF (861.8 KB) | EPUB
  • 76 Views
  • 5 CrossRef citations
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Open Access
Article
Mindfulness-based stress reduction in patients with differentiated thyroid cancer receiving radioactive iodine therapy: a randomized controlled trial
Tianji Liu, Wenqi Zhang, Shuai Xiao, Lei Xu, Qiang Wen, Lin Bai, Qingjie Ma & Bin Ji
Pages: 467-474
Published online: 04 Jan 2019
AbstractforMindfulness-based stress reduction in patients with differentiated thyroid cancer receiving radioactive iodine therapy: a randomized controlled trial | Full Text | References | PDF (293.6 KB) | EPUB
  • 194 Views
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Open Access
Article
Indoleamine 2,3-dioxygenase expression and overall survival in patients diagnosed with breast cancer in Pakistan
Kashif Asghar, Asif Loya, Iftikhar Ali Rana, Muhammad Tahseen, Muhammad Ishaq, Asim Farooq, Muhammad Abu Bakar & Iqra Masood
Pages: 475-481
Published online: 03 Jan 2019
AbstractforIndoleamine 2,3-dioxygenase expression and overall survival in patients diagnosed with breast cancer in Pakistan | Full Text | References | PDF (1.8 MB) | EPUB
  • 105 Views
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Open Access
Article
Hedychium coronarium extract arrests cell cycle progression, induces apoptosis, and impairs migration and invasion in HeLa cervical cancer cells
Asit Ray, Sudipta Jena, Biswabhusan Dash, Ambika Sahoo, Basudeba Kar, Jeetendranath Patnaik, Pratap Chandra Panda, Sanghamitra Nayak & Namita Mahapatra
Pages: 483-500
Published online: 03 Jan 2019
AbstractforHedychium coronarium extract arrests cell cycle progression, induces apoptosis, and impairs migration and invasion in HeLa cervical cancer cells | Full Text | References | PDF (7.5 MB) | EPUB
  • 257 Views
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Open Access
Article
Evolutionary role of chemotherapy in advanced nasopharyngeal carcinoma: a literature-based network meta-analysis
Li Li, Wei Liang, Jin-Xian Zhu, Chun-Jie Dong, Yuan-Mei Zou, Bi-Cui Ye & Lin Gao
Pages: 501-512
Published online: 04 Jan 2019
AbstractforEvolutionary role of chemotherapy in advanced nasopharyngeal carcinoma: a literature-based network meta-analysis | Full Text | References | PDF (1.2 MB) | EPUB
  • 60 Views
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Open Access

Review

Review Article
Addressing physician barriers to administering cyclin-dependent kinases 4 and 6 inhibitors in first-line treatment of hormone receptor–positive, human epidermal growth factor receptor 2–negative advanced breast cancer
Reshma L Mahtani & Charles L Vogel
Pages: 513-524
Published online: 04 Jan 2019
AbstractforAddressing physician barriers to administering cyclin-dependent kinases 4 and 6 inhibitors in first-line treatment of hormone receptor–positive, human epidermal growth factor receptor 2–negative advanced breast cancer | Full Text | References | PDF (207.6 KB) | EPUB
  • 74 Views
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Open Access

Original Research

Article
FOXN2 is downregulated in breast cancer and regulates migration, invasion, and epithelial– mesenchymal transition through regulation of SLUG
Hui Ye & Meiling Duan
Pages: 525-535
Published online: 04 Jan 2019
AbstractforFOXN2 is downregulated in breast cancer and regulates migration, invasion, and epithelial– mesenchymal transition through regulation of SLUG | Full Text | References | PDF (2.6 MB) | EPUB
  • 80 Views
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Open Access
Article
Pathological nodal staging score for rectal cancer patients treated with radical surgery with or without neoadjuvant therapy: a postoperative decision tool
Weixing Dai, Yaqi Li, Zhenyu Wu, Yang Feng, Sanjun Cai, Ye Xu, Qingguo Li & Guoxiang Cai
Pages: 537-546
Published online: 07 Jan 2019
AbstractforPathological nodal staging score for rectal cancer patients treated with radical surgery with or without neoadjuvant therapy: a postoperative decision tool | Full Text | References | PDF (1.6 MB) | EPUB
  • 60 Views
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Open Access
Article
Overexpression of Notch3 is associated with metastasis and poor prognosis in osteosarcoma patients
Xue-Feng Tang, Ya Cao, Dong-Bin Peng, Guo-Sheng Zhao, Ying Zeng, Zi-Ran Gao, Yang-Fan Lv & Qiao-Nan Guo
Pages: 547-559
Published online: 08 Jan 2019
AbstractforOverexpression of Notch3 is associated with metastasis and poor prognosis in osteosarcoma patients | Full Text | References | PDF (4.8 MB) | EPUB
  • 94 Views
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Open Access

Review

Review Article
Efficacy and safety of celecoxib on the incidence of recurrent colorectal adenomas: a systematic review and meta-analysis
Sajesh K Veettil, Surakit Nathisuwan, Siew Mooi Ching, Peerawat Jinatongthai, Kean Ghee Lim, Siang Tong Kew & Nathorn Chaiyakunapruk
Pages: 561-571
Published online: 09 Jan 2019
AbstractforEfficacy and safety of celecoxib on the incidence of recurrent colorectal adenomas: a systematic review and meta-analysis | Full Text | References | PDF (277.4 KB) | EPUB
  • 93 Views
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Open Access

Original Research

Article
ATR activated by EB virus facilitates chemotherapy resistance to cisplatin or 5-fluorouracil in human nasopharyngeal carcinoma
Bo Zhang, Bomiao Cui, Jintao Du, Xin Shen, Kun Wang, Jiao Chen, Liying Xiao, Chongkui Sun & Yan Li
Pages: 573-585
Published online: 09 Jan 2019
AbstractforATR activated by EB virus facilitates chemotherapy resistance to cisplatin or 5-fluorouracil in human nasopharyngeal carcinoma | Full Text | References | PDF (5.2 MB) | EPUB
  • 92 Views
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Open Access

Review

Review Article
High prevalence of secondary bladder cancer in men on radiotherapy for prostate cancer: evidence from a meta-analysis
Shankun Zhao, Qiang Xie, Redian Yang, Jiamin Wang, Chaofeng Zhang, Lianmin Luo, Zhiguo Zhu, Yangzhou Liu, Ermao Li & Zhigang Zhao
Pages: 587-598
Published online: 10 Jan 2019
AbstractforHigh prevalence of secondary bladder cancer in men on radiotherapy for prostate cancer: evidence from a meta-analysis | Full Text | References | PDF (464.2 KB) | EPUB
  • 86 Views
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Open Access

Original Research

Article
Genetic analysis of subsequent second primary malignant neoplasms in long-term pancreatic cancer survivors suggests new potential hereditary genetic alterations
Martin Lovecek, Marketa Janatova, Pavel Skalicky, Tomas Zemanek, Roman Havlik, Jiri Ehrmann, Ondrej Strouhal, Petra Zemankova, Klara Lhotova, Marianna Borecka, Jana Soukupova, Hana Svebisova, Pavel Soucek, Viktor Hlavac, Zdenek Kleibl, Cestmir Neoral, Bohuslav Melichar & Beatrice Mohelnikova-Duchonova
Pages: 599-609
Published online: 10 Jan 2019
AbstractforGenetic analysis of subsequent second primary malignant neoplasms in long-term pancreatic cancer survivors suggests new potential hereditary genetic alterations | Full Text | References | PDF (209.4 KB) | EPUB
  • 75 Views
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Open Access
Article
RETRACTED ARTICLE: Long noncoding RNA SNHG6 functions as a competing endogenous RNA by sponging miR-181a-5p to regulate E2F5 expression in colorectal cancer
Chen Yu, Junxi Sun, Xiaogang Leng & Jianxiu Yang
Pages: 611-624
Published online: 10 Jan 2019
AbstractforRETRACTED ARTICLE: Long noncoding RNA SNHG6 functions as a competing endogenous RNA by sponging miR-181a-5p to regulate E2F5 expression in colorectal cancer | PDF (5.2 MB)
  • 21 Views
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Open Access
Article
Peptidylarginine deiminase 4 overexpression resensitizes MCF-7/ADR breast cancer cells to adriamycin via GSK3β/p53 activation
Qianqian Zhou, Chao Song, Xiaoqiu Liu, Hao Qin, Lixia Miao & Xuesen Zhang
Pages: 625-636
Published online: 10 Jan 2019
AbstractforPeptidylarginine deiminase 4 overexpression resensitizes MCF-7/ADR breast cancer cells to adriamycin via GSK3β/p53 activation | Full Text | References | PDF (3.8 MB) | EPUB
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Article
MicroRNA-4458 suppresses migration and epithelial–mesenchymal transition via targeting HMGA1 in non-small-cell lung cancer cells
Yu Ma, Xuena Li, Song Chen, Bulin Du & Yaming Li
Pages: 637-649
Published online: 10 Jan 2019
AbstractforMicroRNA-4458 suppresses migration and epithelial–mesenchymal transition via targeting HMGA1 in non-small-cell lung cancer cells | Full Text | References | PDF (6.2 MB) | EPUB
  • 83 Views
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Article
lncRNA WT1-AS inhibits the aggressiveness of cervical cancer cell via regulating p53 expression via sponging miR-330-5p
LiJuan Cui, ManMan Nai, Ke Zhang, Lu Li & RuiMin Li
Pages: 651-667
Published online: 11 Jan 2019
AbstractforlncRNA WT1-AS inhibits the aggressiveness of cervical cancer cell via regulating p53 expression via sponging miR-330-5p | Full Text | References | PDF (6.6 MB) | EPUB
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Article
Effect of bisphosphonates on local recurrence of giant cell tumor of bone: a meta-analysis
Mingmin Shi, Lei Chen, Yangxin Wang, Wei Wang, Yujie Zhang & Shigui Yan
Pages: 669-680
Published online: 11 Jan 2019
AbstractforEffect of bisphosphonates on local recurrence of giant cell tumor of bone: a meta-analysis | Full Text | References | PDF (694.9 KB) | EPUB
  • 131 Views
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Article
Metformin induces apoptotic cytotoxicity depending on AMPK/PKA/GSK-3β-mediated c-FLIPL degradation in non-small cell lung cancer
Zhuang Luo, Tingting Zhu, Wei Luo, Yuanyuan Lv, Liyan Zhang, Chu Wang, Min Li, Wenjuan Wu & Shaoqing Shi
Pages: 681-689
Published online: 11 Jan 2019
AbstractforMetformin induces apoptotic cytotoxicity depending on AMPK/PKA/GSK-3β-mediated c-FLIPL degradation in non-small cell lung cancer | Full Text | References | PDF (1.6 MB) | EPUB
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Corrigendum

Correction
Securidaca–saponins are natural inhibitors of AKT, MCL-1, and BCL2L1 in cervical cancer cells [Corrigendum]
Page: 691
Published online: 15 Jan 2019
CitationforSecuridaca–saponins are natural inhibitors of AKT, MCL-1, and BCL2L1 in cervical cancer cells [Corrigendum] | Full Text | PDF (344.8 KB) | EPUB
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Original Research

Article
A sample model established by S-index predicting overall survival after curative resection of primary hepatocellular carcinoma
Lei Chen, Bin-Bin Cai, Chao-Jun Zhou, Xiang-Qing Hou, Si-Pin Hu, Guan Fang, Wen-Chao Chen, Lin-Hui Li & Wen-Jun Yang
Pages: 693-703
Published online: 14 Jan 2019
AbstractforA sample model established by S-index predicting overall survival after curative resection of primary hepatocellular carcinoma | Full Text | References | PDF (1.8 MB) | EPUB
  • 56 Views
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Review

Review Article
Type 2 diabetes mellitus increases the risk of hepatocellular carcinoma in subjects with chronic hepatitis B virus infection: a meta-analysis and systematic review
Yifei Tan, Shiyou Wei, Wei Zhang, Jian Yang, Jiayin Yang & Lunan Yan
Pages: 705-713
Published online: 14 Jan 2019
AbstractforType 2 diabetes mellitus increases the risk of hepatocellular carcinoma in subjects with chronic hepatitis B virus infection: a meta-analysis and systematic review | Full Text | References | PDF (440 KB) | EPUB
  • 151 Views
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Original Research

Article
Aberrant CEACAM19 expression is associated with metastatic phenotype in penile cancer
Xiheng Hu, Mingfeng Chen, Yangle Li, Yin Wang, Sailan Wen & Fu Jun
Pages: 715-725
Published online: 14 Jan 2019
AbstractforAberrant CEACAM19 expression is associated with metastatic phenotype in penile cancer | Full Text | References | PDF (4.7 MB) | EPUB
  • 59 Views
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Article
Comparative study of adjuvant chemotherapeutic efficacy of docetaxel plus cyclophosphamide and doxorubicin plus cyclophosphamide in female breast cancer
Muhammad Adeel, Muhammad Asif, Muhammad Naeem Faisal, Muhammad Hasanain Chaudary, Muhammad Sheraz Malik & Muhammad Khalid
Pages: 727-739
Published online: 15 Jan 2019
AbstractforComparative study of adjuvant chemotherapeutic efficacy of docetaxel plus cyclophosphamide and doxorubicin plus cyclophosphamide in female breast cancer | Full Text | References | PDF (2.3 MB) | EPUB
  • 135 Views
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Article
Neoadjuvant chemoradiation for locally advanced rectal cancer: a systematic review of the literature with network meta-analysis
Min Chen, Liang-zhou Chen, Lin Xu, Jin-song Zhang & Xue Song
Pages: 741-758
Published online: 15 Jan 2019
AbstractforNeoadjuvant chemoradiation for locally advanced rectal cancer: a systematic review of the literature with network meta-analysis | Full Text | References | PDF (569.8 KB) | EPUB
  • 77 Views
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Article
Determining the optimal cutoff point for lymph node density and its impact on overall survival in children with Wilms’ tumor
Zhenyu Pan, Qingting Bu, Haisheng You, Jin Yang, Qingqing Liu & Jun Lyu
Pages: 759-766
Published online: 15 Jan 2019
AbstractforDetermining the optimal cutoff point for lymph node density and its impact on overall survival in children with Wilms’ tumor | Full Text | References | PDF (838.7 KB) | EPUB
  • 66 Views
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Article
TINAGL1 promotes hepatocellular carcinogenesis through the activation of TGF-β signaling-medicated VEGF expression
Lu Sun, Zihui Dong, Hongli Gu, Zhixian Guo & Zujiang Yu
Pages: 767-775
Published online: 15 Jan 2019
AbstractforTINAGL1 promotes hepatocellular carcinogenesis through the activation of TGF-β signaling-medicated VEGF expression | Full Text | References | PDF (4 MB) | EPUB
  • 92 Views
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Review

Review Article
Dysregulation of ncRNAs located at the DLK1‑DIO3 imprinted domain: involvement in urological cancers
Jiangfeng Li, Haixiang Shen, Haiyun Xie, Yufan Ying, Ke Jin, Huaqing Yan, Song Wang, Mingjie Xu, Xiao Wang, Xin Xu & Liping Xie
Pages: 777-787
Published online: 15 Jan 2019
AbstractforDysregulation of ncRNAs located at the DLK1‑DIO3 imprinted domain: involvement in urological cancers | Full Text | References | PDF (523.9 KB) | EPUB
  • 84 Views
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Original Research

Article
Outcome and prognostic factors following palliative craniospinal irradiation for leptomeningeal carcinomatosis
Rami A El Shafie, Karina Böhm, Dorothea Weber, Kristin Lang, Fabian Schlaich, Sebastian Adeberg, Angela Paul, Matthias F Haefner, Sonja Katayama, Florian Sterzing, Juliane Hörner-Rieber, Sarah Löw, Klaus Herfarth, Jürgen Debus, Stefan Rieken & Denise Bernhardt
Pages: 789-801
Published online: 17 Jan 2019
AbstractforOutcome and prognostic factors following palliative craniospinal irradiation for leptomeningeal carcinomatosis | Full Text | References | PDF (538 KB) | EPUB
  • 105 Views
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Article
MNX1-AS1 is a functional oncogene that induces EMT and activates the AKT/mTOR pathway and MNX1 in breast cancer
Yue Cheng, Yiqi Pan, Yiyuan Pan & Ouchen Wang
Pages: 803-812
Published online: 17 Jan 2019
AbstractforMNX1-AS1 is a functional oncogene that induces EMT and activates the AKT/mTOR pathway and MNX1 in breast cancer | Full Text | References | PDF (3.8 MB) | EPUB
  • 89 Views
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Article
Systemic immune-inflammation index and ultrasonographic classification of breast imaging-reporting and data system predict outcomes of triple-negative breast cancer
Ping Wang, Wensheng Yue, Wenyan Li, Yuqun Luo, Zukun Li, Yi Shao & Zhizhong He
Pages: 813-819
Published online: 17 Jan 2019
AbstractforSystemic immune-inflammation index and ultrasonographic classification of breast imaging-reporting and data system predict outcomes of triple-negative breast cancer | Full Text | References | PDF (198.7 KB) | EPUB
  • 241 Views
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Article
PUF60 accelerates the progression of breast cancer through downregulation of PTEN expression
Dongying Sun, Wei Lei, Xiaodong Hou, Hui Li & Wenlu Ni
Pages: 821-830
Published online: 17 Jan 2019
AbstractforPUF60 accelerates the progression of breast cancer through downregulation of PTEN expression | Full Text | References | PDF (3.7 MB) | EPUB
  • 87 Views
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Article
High-grade endometrial stromal sarcoma: a retrospective study of factors influencing prognosis
Yan-Yan Zhang, Yan Li, Meng Qin, Yan Cai, Ying Jin & Ling-Ya Pan
Pages: 831-837
Published online: 17 Jan 2019
AbstractforHigh-grade endometrial stromal sarcoma: a retrospective study of factors influencing prognosis | Full Text | References | PDF (519.4 KB) | EPUB
  • 157 Views
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Article
TMEFF1 overexpression and its mechanism for tumor promotion in ovarian cancer
Xin Nie, Cong Liu, Qian Guo, Ming-jun Zheng, Ling-ling Gao, Xiao Li, Da-wo Liu, Lian-cheng Zhu, Juan-juan Liu & Bei Lin
Pages: 839-855
Published online: 17 Jan 2019
AbstractforTMEFF1 overexpression and its mechanism for tumor promotion in ovarian cancer | Full Text | References | PDF (9.7 MB) | EPUB
  • 88 Views
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Article
Clinicopathological and prognostic significance of CDH1 hypermethylation in hepatocellular carcinoma: a meta-analysis
Xiaoyu Wu, Xuequan Yao, Qinhong Cao, Zhenfeng Wu, Zhaojing Wang, Fukun Liu & Lizong Shen
Pages: 857-864
Published online: 17 Jan 2019
AbstractforClinicopathological and prognostic significance of CDH1 hypermethylation in hepatocellular carcinoma: a meta-analysis | Full Text | References | PDF (782.5 KB) | EPUB
  • 142 Views
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Article
The novel sugar transporter SLC50A1 as a potential serum-based diagnostic and prognostic biomarker for breast cancer
Yu Wang, Yao Shu, Congyang Gu & Yu Fan
Pages: 865-876
Published online: 17 Jan 2019
AbstractforThe novel sugar transporter SLC50A1 as a potential serum-based diagnostic and prognostic biomarker for breast cancer | Full Text | References | PDF (1.8 MB) | EPUB
  • 82 Views
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Article
Integrated analysis of lncRNA-associated ceRNA network reveals potential biomarkers for the prognosis of hepatitis B virus-related hepatocellular carcinoma
Hongyan Li, Xiaonan Zhao, Chenghua Li, Chuanlun Sheng & Zhenzi Bai
Pages: 877-897
Published online: 17 Jan 2019
AbstractforIntegrated analysis of lncRNA-associated ceRNA network reveals potential biomarkers for the prognosis of hepatitis B virus-related hepatocellular carcinoma | Full Text | References | PDF (7.6 MB) | EPUB
  • 93 Views
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Article
Outcomes of health-related quality of life after open, laparoscopic, or robot-assisted radical prostatectomy in China
Wei Huang, Yan Zhang, Bai-Hua Shen, Shuo Wang, Hong-Zhou Meng & Xiao-Dong Jin
Pages: 899-907
Published online: 18 Jan 2019
AbstractforOutcomes of health-related quality of life after open, laparoscopic, or robot-assisted radical prostatectomy in China | Full Text | References | PDF (392.7 KB) | EPUB
  • 85 Views
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Article
Systemic inflammation response index predicts prognosis in patients with clear cell renal cell carcinoma: a propensity score-matched analysis
Zhen Chen, Kai Wang, Hao Lu, Dong Xue, Min Fan, Qianfeng Zhuang, Shuai Yin, Xiaozhou He & Renfang Xu
Pages: 909-919
Published online: 18 Jan 2019
AbstractforSystemic inflammation response index predicts prognosis in patients with clear cell renal cell carcinoma: a propensity score-matched analysis | Full Text | References | PDF (1.7 MB) | EPUB
  • 73 Views
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Article
Feasibility of computer-assisted diagnosis for breast ultrasound: the results of the diagnostic performance of S-detect from a single center in China
Chenyang Zhao, Mengsu Xiao, Yuxin Jiang, He Liu, Ming Wang, Hongyan Wang, Qiang Sun & Qingli Zhu
Pages: 921-930
Published online: 23 Jan 2019
AbstractforFeasibility of computer-assisted diagnosis for breast ultrasound: the results of the diagnostic performance of S-detect from a single center in China | Full Text | References | PDF (5.7 MB) | EPUB
  • 138 Views
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Article
Lipase member H is a downstream molecular target of hypoxia inducible factor-1α and promotes papillary thyroid carcinoma cell migration in BCPAP and KTC-1 cell lines
Yuefeng Li, Xiaofen Zhou, Qiongying Zhang, Endong Chen, Yihan Sun, Danrong Ye, Ouchen Wang, Xiaohua Zhang & Jianxin Lyu
Pages: 931-941
Published online: 22 Jan 2019
AbstractforLipase member H is a downstream molecular target of hypoxia inducible factor-1α and promotes papillary thyroid carcinoma cell migration in BCPAP and KTC-1 cell lines | Full Text | References | PDF (5 MB) | EPUB
  • 78 Views
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Article
Trends in the incidence, treatment, and survival of patients with lung cancer in the last four decades
Tao Lu, Xiaodong Yang, Yiwei Huang, Mengnan Zhao, Ming Li, Ke Ma, Jiacheng Yin, Cheng Zhan & Qun Wang
Pages: 943-953
Published online: 21 Jan 2019
AbstractforTrends in the incidence, treatment, and survival of patients with lung cancer in the last four decades | Full Text | References | PDF (6.1 MB) | EPUB
  • 1193 Views
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Article
Suppression of miR-21-3p enhances TRAIL-mediated apoptosis in liver cancer stem cells by suppressing the PI3K/Akt/Bad cascade via regulating PTEN
Yingwei Zhu, Hong Tang, Lili Zhang, Lei Gong, Gaojue Wu, Jingbin Ni & Xuejun Tang
Pages: 955-968
Published online: 22 Jan 2019
AbstractforSuppression of miR-21-3p enhances TRAIL-mediated apoptosis in liver cancer stem cells by suppressing the PI3K/Akt/Bad cascade via regulating PTEN | Full Text | References | PDF (3.2 MB) | EPUB
  • 85 Views
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Review

Review Article
Function of microRNA-145 and mechanisms underlying its role in malignant tumor diagnosis and treatment
Dong Ye, Zhisen Shen & Shuihong Zhou
Pages: 969-979
Published online: 22 Jan 2019
AbstractforFunction of microRNA-145 and mechanisms underlying its role in malignant tumor diagnosis and treatment | Full Text | References | PDF (181.1 KB) | EPUB
  • 170 Views
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Original Research

Article
Transcatheter arterial embolization combined with hypoxia-replicative oncolytic adenovirus perfusion enhances the therapeutic effect of hepatic carcinoma
Hongsen Zhang, Fu Xiong, Kun Qian, Yiming Liu, Bin Liang, Bin Xiong, Fan Yang & Chuansheng Zheng
Pages: 981-996
Published online: 23 Jan 2019
AbstractforTranscatheter arterial embolization combined with hypoxia-replicative oncolytic adenovirus perfusion enhances the therapeutic effect of hepatic carcinoma | Full Text | References | PDF (8.5 MB) | EPUB
  • 71 Views
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Article
Clinical characteristics of extranodal NK/T-cell lymphoma-associated hemophagocytic lymphohistiocytosis
Yi-Zhen Liu, Lan-Qing Bi, Gui-Lin Chang, Ye Guo & Si Sun
Pages: 997-1002
Published online: 23 Jan 2019
AbstractforClinical characteristics of extranodal NK/T-cell lymphoma-associated hemophagocytic lymphohistiocytosis | Full Text | References | PDF (1.2 MB) | EPUB
  • 89 Views
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Article
Clear cell adenocarcinoma of the lung: a population-based study
Shu-Jun Ke, Peng Wang & Bing Xu
Pages: 1003-1012
Published online: 22 Jan 2019
AbstractforClear cell adenocarcinoma of the lung: a population-based study | Full Text | References | PDF (1.3 MB) | EPUB
  • 61 Views
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Article
Implementation of sorafenib treatment for advanced hepatocellular carcinoma: an illustration of current practice in Taiwan
Kun-Ming Chan, Tsung-Han Wu, Chih-Hsien Cheng, Chen-Fang Lee, Ting-Jung Wu, Hong-Shiue Chou & Wei-Chen Lee
Pages: 1013-1021
Published online: 22 Jan 2019
AbstractforImplementation of sorafenib treatment for advanced hepatocellular carcinoma: an illustration of current practice in Taiwan | Full Text | References | PDF (322.9 KB) | EPUB
  • 64 Views
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Article
Synergistic cytotoxicity of homoharringtonine and etoposide in acute myeloid leukemia cells involves disrupted antioxidant defense
Jingjing Zhang, Huayun Geng, Ling Liu & Hao Zhang
Pages: 1023-1032
Published online: 22 Jan 2019
AbstractforSynergistic cytotoxicity of homoharringtonine and etoposide in acute myeloid leukemia cells involves disrupted antioxidant defense | Full Text | References | PDF (1.5 MB) | EPUB
  • 73 Views
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Article
Circular RNA hsa_circ_0072309 inhibits proliferation and invasion of breast cancer cells via targeting miR-492
Lin Yan, Min Zheng & Hua Wang
Pages: 1033-1041
Published online: 22 Jan 2019
AbstractforCircular RNA hsa_circ_0072309 inhibits proliferation and invasion of breast cancer cells via targeting miR-492 | Full Text | References | PDF (1.6 MB) | EPUB
  • 69 Views
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Review

Review Article
Prognostic value of miR17-92 family in patients with digestive system cancers: a systematic review and meta-analysis
Xiaoyun Zhang, Shijie Zhang, Qin He, Xiaojuan Gao, Lijun Yang, Peipei Xu, Rui Zhao, Qian Wang, Lina Zhang & Panpan Zhao
Pages: 1043-1058
Published online: 22 Jan 2019
AbstractforPrognostic value of miR17-92 family in patients with digestive system cancers: a systematic review and meta-analysis | Full Text | References | PDF (6 MB) | EPUB
  • 70 Views
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Original Research

Article
Competing risk analysis of primary tracheal carcinoma based on SEER database
HongXiang Gao, Xuan He, JianFei Du, SanHu Yang, Yang Wang, JunWei Zhang & ChenNian Zhao
Pages: 1059-1065
Published online: 24 Jan 2019
AbstractforCompeting risk analysis of primary tracheal carcinoma based on SEER database | Full Text | References | PDF (295 KB) | EPUB
  • 67 Views
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Letter

Letter
Letter to the editor regarding the publication “Association between matrix-metalloproteinase polymorphisms and prostate cancer risk: a meta-analysis and systematic review”
Rama Jayaraj & Chellan Kumarasamy
Pages: 1067-1068
Published online: 24 Jan 2019
CitationforLetter to the editor regarding the publication “Association between matrix-metalloproteinase polymorphisms and prostate cancer risk: a meta-analysis and systematic review” | Full Text | References | PDF (124.2 KB) | EPUB
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Original Research

Article
Expression and biological function of rhotekin in gastric cancer through regulating p53 pathway
Meng-Yao Sun, Hong Zhang, Jie Tao, Zhen-Hua Ni, Qiu-Xue Wu & Qing-Feng Tang
Pages: 1069-1080
Published online: 25 Jan 2019
AbstractforExpression and biological function of rhotekin in gastric cancer through regulating p53 pathway | Full Text | References | PDF (4.2 MB) | EPUB
  • 73 Views
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Article
Oncologic outcome of parotid mucoepidermoid carcinoma in pediatric patients
Qigen Fang, Fei Liu & Dongjie Seng
Pages: 1081-1085
Published online: 29 Jan 2019
AbstractforOncologic outcome of parotid mucoepidermoid carcinoma in pediatric patients | Full Text | References | PDF (216.8 KB) | EPUB
  • 77 Views
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Article
Identifying the reasons for delayed presentation of Pakistani breast cancer patients at a tertiary care hospital
Faisal Gulzar, Muhammad Shoaib Akhtar, Rafshan Sadiq, Sajid Bashir, Sajida Jamil & Shahid Mahmood Baig
Pages: 1087-1096
Published online: 29 Jan 2019
AbstractforIdentifying the reasons for delayed presentation of Pakistani breast cancer patients at a tertiary care hospital | Full Text | References | PDF (207.7 KB) | EPUB
  • 636 Views
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Article
Postmastectomy radiotherapy using three different techniques: a retrospective evaluation of the incidental dose distribution in the internal mammary nodes
Wei Wang, Yingjie Zhang, Min Xu, Qian Shao, Tao Sun, Ting Yu, Xijun Liu & Jianbin Li
Pages: 1097-1106
Published online: 30 Jan 2019
AbstractforPostmastectomy radiotherapy using three different techniques: a retrospective evaluation of the incidental dose distribution in the internal mammary nodes | Full Text | References | PDF (1.9 MB) | EPUB
  • 64 Views
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Article
Pathological risk factors for lymph node metastasis in patients with submucosal invasive colorectal carcinoma
Qiongyan Zhang, Lei Wang, Dan Huang, Midie Xu, Weiwei Weng, Shujuan Ni, Cong Tan & Weiqi Sheng
Pages: 1107-1114
Published online: 30 Jan 2019
AbstractforPathological risk factors for lymph node metastasis in patients with submucosal invasive colorectal carcinoma | Full Text | References | PDF (4.3 MB) | EPUB
  • 74 Views
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Article
SERS-based detection of haptoglobin in ovarian cyst fluid as a point-of-care diagnostic assay for epithelial ovarian cancer
Jayakumar Perumal, Aniza Puteri Mahyuddin, Ghayathri Balasundaram, Douglas Goh, Chit Yaw Fu, Agne Kazakeviciute, US Dinish, Mahesh Choolani & Malini Olivo
Pages: 1115-1124
Published online: 31 Jan 2019
AbstractforSERS-based detection of haptoglobin in ovarian cyst fluid as a point-of-care diagnostic assay for epithelial ovarian cancer | Full Text | References | PDF (1.3 MB) | EPUB
  • 164 Views
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Article
Modeling risk assessment for breast cancer in symptomatic women: a Saudi Arabian study
Anwar E Ahmed, Donna K McClish, Thamer Alghamdi, Abdulmajeed Alshehri, Yasser Aljahdali, Khalid Aburayah, Abdulrahman Almaymoni, Monirah Albaijan, Hamdan Al-Jahdali & Abdul Rahman Jazieh
Pages: 1125-1132
Published online: 04 Feb 2019
AbstractforModeling risk assessment for breast cancer in symptomatic women: a Saudi Arabian study | Full Text | References | PDF (389.4 KB) | EPUB
  • 77 Views
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Article
Performance characteristics of prostate-specific antigen density and biopsy primary Gleason score to predict biochemical failure in patients with intermediate prostate cancer who underwent radical prostatectomy
Chao Peng, Jun Zhang & Jianquan Hou
Pages: 1133-1139
Published online: 01 Feb 2019
AbstractforPerformance characteristics of prostate-specific antigen density and biopsy primary Gleason score to predict biochemical failure in patients with intermediate prostate cancer who underwent radical prostatectomy | Full Text | References | PDF (308.3 KB) | EPUB
  • 65 Views
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Article
Dexamethasone inhibits the proliferation of tumor cells
Yuantao Wu, Rui Xia, Chungang Dai, Suji Yan, Tao Xie, Bing Liu, Lei Gan, Zhixiang Zhuang & Qiang Huang
Pages: 1141-1154
Published online: 01 Feb 2019
AbstractforDexamethasone inhibits the proliferation of tumor cells | Full Text | References | PDF (4.7 MB) | EPUB
  • 134 Views
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Article
Carbon-ion radiotherapy in accelerated hypofractionated active raster-scanning technique for malignant lacrimal gland tumors: feasibility and safety
Sati Akbaba, Kristin Lang, Thomas Held, Klaus Herfarth, Juliane Rieber, Peter Plinkert, Gerd U Auffarth, Stefan Rieken, Juergen Debus & Sebastian Adeberg
Pages: 1155-1166
Published online: 01 Feb 2019
AbstractforCarbon-ion radiotherapy in accelerated hypofractionated active raster-scanning technique for malignant lacrimal gland tumors: feasibility and safety | Full Text | References | PDF (3.3 MB) | EPUB
  • 69 Views
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Article
Rhein shows potent efficacy against non-small-cell lung cancer through inhibiting the STAT3 pathway
Lehe Yang, Jifa Li, Lingyuan Xu, Shichong Lin, Youqun Xiang, Xuanxuan Dai, Guang Liang, Xiaoying Huang, Jiandong Zhu & Chengguang Zhao
Pages: 1167-1176
Published online: 01 Feb 2019
AbstractforRhein shows potent efficacy against non-small-cell lung cancer through inhibiting the STAT3 pathway | Full Text | References | PDF (4.6 MB) | EPUB
  • 114 Views
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Article
miR-600 inhibits lung cancer via downregulating the expression of METTL3
Wenwen Wei, Baosheng Huo & Xiulan Shi
Pages: 1177-1187
Published online: 01 Feb 2019
AbstractformiR-600 inhibits lung cancer via downregulating the expression of METTL3 | Full Text | References | PDF (7.7 MB) | EPUB
  • 102 Views
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Article
Statin and metformin therapy in prostate cancer patients with hyperlipidemia who underwent radiotherapy: a population-based cohort study
Ke Li, Jie Si-Tu, Jianguang Qiu, Li Lu, Yunhua Mao, Hua Zeng, Mingkun Chen, Caiyong Lai, Heng-Jui Chang & Dejuan Wang
Pages: 1189-1197
Published online: 04 Feb 2019
AbstractforStatin and metformin therapy in prostate cancer patients with hyperlipidemia who underwent radiotherapy: a population-based cohort study | Full Text | References | PDF (354 KB) | EPUB
  • 92 Views
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Article
Attenuated ZHX3 expression serves as a potential biomarker that predicts poor clinical outcomes in breast cancer patients
Yanjie You, Yuhong Ma, Qiang Wang, Zhengcai Ye, Yanhong Deng & Feihu Bai
Pages: 1199-1210
Published online: 05 Feb 2019
AbstractforAttenuated ZHX3 expression serves as a potential biomarker that predicts poor clinical outcomes in breast cancer patients | Full Text | References | PDF (3.3 MB) | EPUB
  • 77 Views
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Article
Loss of KCNJ15 expression promotes malignant phenotypes and correlates with poor prognosis in renal carcinoma
Yang Liu, Han Wang, Beibei Ni, Jinghua Zhang, Shi Li, Yuqian Huang, Yanling Cai, Hongbing Mei & Zesong Li
Pages: 1211-1220
Published online: 07 Feb 2019
AbstractforLoss of KCNJ15 expression promotes malignant phenotypes and correlates with poor prognosis in renal carcinoma | Full Text | References | PDF (4.7 MB) | EPUB
  • 104 Views
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Article
The Nrf2/HO-1 axis can be a prognostic factor in clear cell renal cell carcinoma
Yu Deng, Yong Wu, Ping Zhao, Weiwei Weng, Min Ye, Hui Sun, Midie Xu & Chaofu Wang
Pages: 1221-1230
Published online: 07 Feb 2019
AbstractforThe Nrf2/HO-1 axis can be a prognostic factor in clear cell renal cell carcinoma | Full Text | References | PDF (5.2 MB) | EPUB
  • 71 Views
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Article
Ultrasound-guided fine-needle aspiration biopsy of thyroid nodules <10 mm in the maximum diameter: does size matter?
Yi-jun Lyu, Fang Shen, Yun Yan, Ming-zhu Situ, Wei-zhu Wu, Guo-qiang Jiang & Ya-ya Chen
Pages: 1231-1236
Published online: 07 Feb 2019
AbstractforUltrasound-guided fine-needle aspiration biopsy of thyroid nodules <10 mm in the maximum diameter: does size matter? | Full Text | References | PDF (161.1 KB) | EPUB
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Article
Pretreatment detection of circulating and tissue CD133+ CD44+ cancer stem cells as a prognostic factor affecting the outcomes in Egyptian patients with colorectal cancer
Asmaa M Zahran, Amal Rayan, Hussein Fakhry, Alia M Attia, Ahmed M Ashmawy, Ahmed Soliman, Azza Elkady & Helal F Hetta
Pages: 1237-1248
Published online: 07 Feb 2019
AbstractforPretreatment detection of circulating and tissue CD133+ CD44+ cancer stem cells as a prognostic factor affecting the outcomes in Egyptian patients with colorectal cancer | Full Text | References | PDF (1.5 MB) | EPUB
  • 108 Views
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Article
DNA methylation-mediated silencing of miR-204 is a potential prognostic marker for papillary thyroid carcinoma
Fada Xia, Wenlong Wang, Bo Jiang, Yong Chen & Xinying Li
Pages: 1249-1262
Published online: 08 Feb 2019
AbstractforDNA methylation-mediated silencing of miR-204 is a potential prognostic marker for papillary thyroid carcinoma | Full Text | References | PDF (5.7 MB) | EPUB
  • 65 Views
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Article
Overexpression of COL5A1 promotes tumor progression and metastasis and correlates with poor survival of patients with clear cell renal cell carcinoma
Gang Feng, Hui-Min Ma, Hou-Bao Huang, Ya-Wei Li, Peng Zhang, Jian-Jun Huang, Long Cheng & Guo-Rong Li
Pages: 1263-1274
Published online: 07 Feb 2019
AbstractforOverexpression of COL5A1 promotes tumor progression and metastasis and correlates with poor survival of patients with clear cell renal cell carcinoma | Full Text | References | PDF (4.2 MB) | EPUB
  • 77 Views
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Article
Establishment and characterization of the GC-030-35 cell line derived from gastric hepatoid adenocarcinoma
Jingsun Wei, Yiqi Xue, Xinying Huo, Rongbo Han, Xinyu Su, Yan Jin, Wenjing Zhao, Yuetong Chen, Honghong Zhang, Jiali Dai & Jinfei Chen
Pages: 1275-1287
Published online: 08 Feb 2019
AbstractforEstablishment and characterization of the GC-030-35 cell line derived from gastric hepatoid adenocarcinoma | Full Text | References | PDF (6.9 MB) | EPUB
  • 71 Views
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Article
Real-world cost-effectiveness of targeted therapy in metastatic renal cell carcinoma in Sweden: a population-based retrospective analysis
Josefine Redig, Johan Dalén, Ulrika Harmenberg, Magnus Lindskog, Börje Ljungberg, Sven Lundstam, Rickard Sandin, Thomas Wahlgren, Örjan Åkerborg & Maria Jakobsson
Pages: 1289-1297
Published online: 08 Feb 2019
AbstractforReal-world cost-effectiveness of targeted therapy in metastatic renal cell carcinoma in Sweden: a population-based retrospective analysis | Full Text | References | PDF (265.5 KB) | EPUB
  • 70 Views
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Article
Long-term survival of patients with locally advanced esophageal squamous cell carcinoma receiving esophagectomy following neoadjuvant chemotherapy: a cohort study
Zekai Huang, Shaolei Li, Xin Yang, Fangliang Lu, Miao Huang, Shanyuan Zhang, Ying Xiong, Panpan Zhang, Jiahui Si, Yuanyuan Ma & Yue Yang
Pages: 1299-1308
Published online: 08 Feb 2019
AbstractforLong-term survival of patients with locally advanced esophageal squamous cell carcinoma receiving esophagectomy following neoadjuvant chemotherapy: a cohort study | Full Text | References | PDF (768.2 KB) | EPUB
  • 63 Views
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Article
PTPN9 induces cell apoptosis by mitigating the activation of Stat3 and acts as a tumor suppressor in colorectal cancer
Dawei Wang, Zhuoxin Cheng, Ming Zhao, Chengbin Jiao, Qinghui Meng, Huayang Pan, Yu Xie, Long Li, Yexing Zhu, Wei Wang, Chunlei Qu & Deshen Liang
Pages: 1309-1319
Published online: 08 Feb 2019
AbstractforPTPN9 induces cell apoptosis by mitigating the activation of Stat3 and acts as a tumor suppressor in colorectal cancer | Full Text | References | PDF (2 MB) | EPUB
  • 79 Views
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Review

Review Article
Novel genetic alterations and their impact on target therapy response in head and neck squamous cell carcinoma
Xiaohua Jiang, Jing Ye, Zhihuai Dong, Sunhong Hu & Mang Xiao
Pages: 1321-1336
Published online: 08 Feb 2019
AbstractforNovel genetic alterations and their impact on target therapy response in head and neck squamous cell carcinoma | Full Text | References | PDF (2.9 MB) | EPUB
  • 99 Views
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Original Research

Article
Claudin gene expression profiles and clinical value in colorectal tumors classified according to their molecular subtype
Sara Cherradi, Pierre Martineau, Céline Gongora & Maguy Del Rio
Pages: 1337-1348
Published online: 13 Feb 2019
AbstractforClaudin gene expression profiles and clinical value in colorectal tumors classified according to their molecular subtype | Full Text | References | PDF (1.5 MB) | EPUB
  • 126 Views
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Article
Activated Wnt signaling promotes growth and progression of AFP-producing gastric cancer in preclinical models
Dongshao Chen, Xiaoting Lin, Cheng Zhang, Guo An, Zhongwu Li, Bin Dong, Lin Shen, Jing Gao & Xiaotian Zhang
Pages: 1349-1362
Published online: 11 Feb 2019
AbstractforActivated Wnt signaling promotes growth and progression of AFP-producing gastric cancer in preclinical models | Full Text | References | PDF (10.1 MB) | EPUB
  • 113 Views
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Article
Efficacy of dose-adjusted EPOCH plus rituximab/R-CHOP regimens and the prognosis analysis in patients with MYC, BCL2/BCL6 gene copy number gain lymphoma and double-hit lymphoma: results from a single institution retrospective clinical study
Qianwen Ma, Yu Chang, Ling Li, Xin Li, Xinhua Wang, Jingjing Wu, Xiaorui Fu, Zhenchang Sun, Hui Yu, Xudong Zhang, Zhiyuan Zhou, Feifei Nan, Zhaoming Li, Xiyang Liu, Qian Zhao, Yang Li, Lan Zhang, Mingzhi Zhang & Lei Zhang
Pages: 1363-1372
Published online: 11 Feb 2019
AbstractforEfficacy of dose-adjusted EPOCH plus rituximab/R-CHOP regimens and the prognosis analysis in patients with MYC, BCL2/BCL6 gene copy number gain lymphoma and double-hit lymphoma: results from a single institution retrospective clinical study | Full Text | References | PDF (497.3 KB)
  • 78 Views
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Article
Role of local treatment including radiotherapy in Barcelona Clinic of Liver Cancer stage C patients: a nationwide cohort analysis in South Korea
Jeongshim Lee, Won Sup Yoon, Woong Sub Koom, Chai Hong Rim & On behalf of the Korean Liver Cancer Study Group
Pages: 1373-1382
Published online: 11 Feb 2019
AbstractforRole of local treatment including radiotherapy in Barcelona Clinic of Liver Cancer stage C patients: a nationwide cohort analysis in South Korea | Full Text | References | PDF (1,011.6 KB) | EPUB
  • 57 Views
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Article
DNA methylation-mediated Klotho silencing is an independent prognostic biomarker of head and neck squamous carcinoma
Yun Zhu, Xuehong Cao, Xiaomeng Zhang, Quan Chen, Lei Wen & Ping Wang
Pages: 1383-1390
Published online: 12 Feb 2019
AbstractforDNA methylation-mediated Klotho silencing is an independent prognostic biomarker of head and neck squamous carcinoma | Full Text | References | PDF (1 MB) | EPUB
  • 75 Views
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Article
The prognostic and predictive value of the combination of the neutrophil-to-lymphocyte ratio and the platelet-to-lymphocyte ratio in patients with hepatocellular carcinoma who receive transarterial chemoembolization therapy
Chaobin He, Yu Zhang, Zhiyuan Cai & Xiaojun Lin
Pages: 1391-1400
Published online: 12 Feb 2019
AbstractforThe prognostic and predictive value of the combination of the neutrophil-to-lymphocyte ratio and the platelet-to-lymphocyte ratio in patients with hepatocellular carcinoma who receive transarterial chemoembolization therapy | Full Text | References | PDF (838.3 KB) | EPUB
  • 72 Views
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Article
Preoperative aspartate aminotransferase-to-platelet-ratio index as a predictor of posthepatectomy liver failure for resectable hepatocellular carcinoma
Rong-Yun Mai, Jia-Zhou Ye, Zhong-Rong Long, Xian-Mao Shi, Tao Bai, Jie Chen, Le-Qun Li, Guo-Bin Wu & Fei-Xiang Wu
Pages: 1401-1414
Published online: 12 Feb 2019
AbstractforPreoperative aspartate aminotransferase-to-platelet-ratio index as a predictor of posthepatectomy liver failure for resectable hepatocellular carcinoma | Full Text | References | PDF (1.8 MB) | EPUB
  • 64 Views
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Article
Circular RNA circHIPK3 promotes cell proliferation and invasion of prostate cancer by sponging miR-193a-3p and regulating MCL1 expression
Dong Chen, Xinxing Lu, Feiya Yang & Nianzeng Xing
Pages: 1415-1423
Published online: 12 Feb 2019
AbstractforCircular RNA circHIPK3 promotes cell proliferation and invasion of prostate cancer by sponging miR-193a-3p and regulating MCL1 expression | Full Text | References | PDF (1.9 MB) | EPUB
  • 71 Views
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Article
Preoperative fasting hyperglycemia is an independent prognostic factor for postoperative survival after gallbladder carcinoma radical surgery
Peng Zheng, Xiaoqian Wang, Zhong Hong, Feixia Shen & Qiyu Zhang
Pages: 1425-1432
Published online: 12 Feb 2019
AbstractforPreoperative fasting hyperglycemia is an independent prognostic factor for postoperative survival after gallbladder carcinoma radical surgery | Full Text | References | PDF (440.5 KB) | EPUB
  • 79 Views
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Article
Comparison of the 7th and 8th edition of American Joint Committee on Cancer (AJCC) staging systems for breast cancer patients: a Surveillance, Epidemiology and End Results (SEER) Analysis
Nan Shao, Chuanbo Xie, Yawei Shi, Runyi Ye, Jianting Long, Huijuan Shi, Zhen Shan, Alastair M Thompson & Ying Lin
Pages: 1433-1442
Published online: 13 Feb 2019
AbstractforComparison of the 7th and 8th edition of American Joint Committee on Cancer (AJCC) staging systems for breast cancer patients: a Surveillance, Epidemiology and End Results (SEER) Analysis | Full Text | References | PDF (1.5 MB) | EPUB
  • 160 Views
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Article
Non-tight junction-related function of claudin-7 in interacting with integrinβ1 to suppress colorectal cancer cell proliferation and migration
Wenjing Li, Chang Xu, Kun Wang, Yuhan Ding & Lei Ding
Pages: 1443-1451
Published online: 13 Feb 2019
AbstractforNon-tight junction-related function of claudin-7 in interacting with integrinβ1 to suppress colorectal cancer cell proliferation and migration | Full Text | References | PDF (3 MB) | EPUB
  • 73 Views
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Article
Relationship between bone mineral density and the risk of breast cancer: a systematic review and dose–response meta-analysis of ten cohort studies
Jian-Hua Chen, Quan Yuan, Ya-Nan Ma, Shi-Han Zhen & De-Liang Wen
Pages: 1453-1464
Published online: 13 Feb 2019
AbstractforRelationship between bone mineral density and the risk of breast cancer: a systematic review and dose–response meta-analysis of ten cohort studies | Full Text | References | PDF (937.4 KB) | EPUB
  • 59 Views
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Article
p53-positive expression in dysplastic surgical margins is a predictor of tumor recurrence in patients with early oral squamous cell carcinoma
Xi-Hu Yang, Liang Ding, Yong Fu, Sheng Chen, Lei Zhang, Xiao-Xin Zhang, Xiao-Feng Huang, Zhan-Yi Lu, Yan-Hong Ni & Qin-Gang Hu
Pages: 1465-1472
Published online: 13 Feb 2019
Abstractforp53-positive expression in dysplastic surgical margins is a predictor of tumor recurrence in patients with early oral squamous cell carcinoma | Full Text | References | PDF (3.3 MB) | EPUB
  • 84 Views
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Article
The distinct clinicopathological and prognostic implications of PIK3CA mutations in breast cancer patients from Central China
Haibo Wu, Wei Wang, Jun Du, Hong Li, Huogang Wang, Liangliang Huang, Hang Xiang, Jing Xie, Xiaoli Liu, Heng Li & Wenchu Lin
Pages: 1473-1492
Published online: 14 Feb 2019
AbstractforThe distinct clinicopathological and prognostic implications of PIK3CA mutations in breast cancer patients from Central China | Full Text | References | PDF (1.8 MB) | EPUB
  • 84 Views
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Article
Early and sustained deep molecular response achieved with nilotinib in high Sokal risk chronic myeloid leukemia patients
Uzma Zaidi, Bushra Kaleem, Munira Borhany, Sidra Maqsood, Naveena Fatima, Gul Sufaida, Saqib Hussain Ansari, Tasneem Farzana & Tahir Sultan Shamsi
Pages: 1493-1502
Published online: 15 Feb 2019
AbstractforEarly and sustained deep molecular response achieved with nilotinib in high Sokal risk chronic myeloid leukemia patients | Full Text | References | PDF (1.3 MB) | EPUB
  • 106 Views
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Article
Significant prognostic values of aquaporin mRNA expression in breast cancer
Lizhe Zhu, Nan Ma, Bin Wang, Lei Wang, Can Zhou, Yu Yan, Jianjun He & Yu Ren
Pages: 1503-1515
Published online: 14 Feb 2019
AbstractforSignificant prognostic values of aquaporin mRNA expression in breast cancer | Full Text | References | PDF (2.6 MB) | EPUB
  • 120 Views
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Article
Polo-like kinase 3 is associated with poor prognosis and regulates proliferation and metastasis in prostate cancer
Chunhao Lin, Shoumin Bai, Tao Du, Yiming Lai, Xianju Chen, Shengmeng Peng, Xiaoming Ma, Wanhua Wu, Zhenghui Guo & Hai Huang
Pages: 1517-1524
Published online: 14 Feb 2019
AbstractforPolo-like kinase 3 is associated with poor prognosis and regulates proliferation and metastasis in prostate cancer | Full Text | References | PDF (2.4 MB) | EPUB
  • 67 Views
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Article
Treatment-related adverse effects with TKIs in patients with advanced or radioiodine refractory differentiated thyroid carcinoma: a systematic review and meta-analysis
Shi-Tong Yu, Jun-Na Ge, Jing-Yi Luo, Zhi-Gang Wei, Bai-Hui Sun & Shang-Tong Lei
Pages: 1525-1532
Published online: 14 Feb 2019
AbstractforTreatment-related adverse effects with TKIs in patients with advanced or radioiodine refractory differentiated thyroid carcinoma: a systematic review and meta-analysis | Full Text | References | PDF (736.4 KB) | EPUB
  • 61 Views
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Methodology

Article
A modified method for isolating human quiescent pancreatic stellate cells
Fu-Tao Meng, Mei Huang, Fang-Fang Fan, Feng Shao, Chao Wang & Qiang Huang
Pages: 1533-1539
Published online: 14 Feb 2019
AbstractforA modified method for isolating human quiescent pancreatic stellate cells | Full Text | References | PDF (3.9 MB) | EPUB
  • 77 Views
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Review

Review Article
Trametes robiniophila Murr: a traditional Chinese medicine with potent anti-tumor effects
Jun Pan, Chenghui Yang, Zhou Jiang & Jian Huang
Pages: 1541-1549
Published online: 14 Feb 2019
AbstractforTrametes robiniophila Murr: a traditional Chinese medicine with potent anti-tumor effects | Full Text | References | PDF (1.1 MB) | EPUB
  • 193 Views
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Original Research

Article
Safety and efficacy assessment of transarterial chemoembolization using drug-eluting beads in patients with hepatocellular carcinoma and arterioportal shunt: a single-center experience
Yu-dong Xiao, Cong Ma, Zi-shu Zhang & Jun Liu
Pages: 1551-1557
Published online: 15 Feb 2019
AbstractforSafety and efficacy assessment of transarterial chemoembolization using drug-eluting beads in patients with hepatocellular carcinoma and arterioportal shunt: a single-center experience | Full Text | References | PDF (858.8 KB) | EPUB
  • 85 Views
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Article
Identification of chromosomal abnormalities and genomic features in near-triploidy/tetraploidy-acute leukemia by fluorescence in situ hybridization
Ruqing Yang, Minghua Jiang, Junzhao Zhao, Hui Chen, Jian Gong, Yaying You, Laiyue Song, Zhen Li & Qian Li
Pages: 1559-1567
Published online: 15 Feb 2019
AbstractforIdentification of chromosomal abnormalities and genomic features in near-triploidy/tetraploidy-acute leukemia by fluorescence in situ hybridization | Full Text | References | PDF (2.7 MB) | EPUB
  • 95 Views
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Article
A tumor map generated from three-dimensional visualization of image fusion for the assessment of microwave ablation of hepatocellular carcinoma: a preliminary study
Chao An, Xin Li, Ping Liang, Jie Yu, Zhigang Cheng, Zhiyu Han, Fangyi Liu & Linan Dong
Pages: 1569-1578
Published online: 15 Feb 2019
AbstractforA tumor map generated from three-dimensional visualization of image fusion for the assessment of microwave ablation of hepatocellular carcinoma: a preliminary study | Full Text | References | PDF (1.7 MB) | EPUB
  • 70 Views
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Article
Concomitant dose escalation with image-guided Tomotherapy in locally advanced mid–low rectal cancer: a single-center study
Jing Zhao, Xiaoliang Liu, Weiping Wang, Ke Hu, Fuquan Zhang, Xiaorong Hou & Qingyu Meng
Pages: 1579-1586
Published online: 15 Feb 2019
AbstractforConcomitant dose escalation with image-guided Tomotherapy in locally advanced mid–low rectal cancer: a single-center study | Full Text | References | PDF (434.2 KB) | EPUB
  • 62 Views
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Article
Comparison of analgesia, adverse effects, and quality of life in cancer patients during treatment of procedural pain with intravenous morphine, fentanyl nasal spray, and fentanyl buccal tablets
Wieslawa Piotrowska, Wojciech Leppert & Mikolaj Majkowicz
Pages: 1587-1600
Published online: 18 Feb 2019
AbstractforComparison of analgesia, adverse effects, and quality of life in cancer patients during treatment of procedural pain with intravenous morphine, fentanyl nasal spray, and fentanyl buccal tablets | Full Text | References | PDF (2.9 MB) | EPUB
  • 147 Views
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Article
RETRACTED ARTICLE: tProtocadherin 17 is a tumor suppressor and is frequently methylated in nasopharyngeal carcinoma
Ya He, Zhihai Wang, Chuan Liu, Zhitao Gong, Yanshi Li, Tao Lu & Guohua Hu
Pages: 1601-1613
Published online: 18 Feb 2019
AbstractforRETRACTED ARTICLE: tProtocadherin 17 is a tumor suppressor and is frequently methylated in nasopharyngeal carcinoma | PDF (7.8 MB)
  • 15 Views
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Article
Prognostic value of mean platelet volume to plateletcrit ratio in patients with osteosarcoma
Bo Gou, Hong Cao, Xinghua Cheng, Wei Shang, Mingqing Xu & Wei Qian
Pages: 1615-1621
Published online: 18 Feb 2019
AbstractforPrognostic value of mean platelet volume to plateletcrit ratio in patients with osteosarcoma | Full Text | References | PDF (411.1 KB) | EPUB
  • 79 Views
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Article
Complete response associated with immune checkpoint inhibitors in advanced non-small-cell lung cancer: a meta-analysis of nine randomized controlled trials
Jie Li, Qi He, Xiu Yu, Khalid Khan, Xuanwen Weng & Minjie Guan
Pages: 1623-1629
Published online: 18 Feb 2019
AbstractforComplete response associated with immune checkpoint inhibitors in advanced non-small-cell lung cancer: a meta-analysis of nine randomized controlled trials | Full Text | References | PDF (626.9 KB) | EPUB
  • 82 Views
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Article
Mismatch repair status and high expression of PD-L1 in nasopharyngeal carcinoma
Liang Zhao, Xiyi Liao, Ganji Hong, Yanzhen Zhuang, Kaili Fu, Peiqiong Chen, Yuhuan Wang, Haojun Chen & Qin Lin
Pages: 1631-1640
Published online: 19 Feb 2019
AbstractforMismatch repair status and high expression of PD-L1 in nasopharyngeal carcinoma | Full Text | References | PDF (7.4 MB) | EPUB
  • 63 Views
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Article
RETRACTED ARTICLE: miR-140-5p alleviates the aggressive progression of Wilms’ tumor through directly targeting TGFBR1 gene
Hailei Wang, Chunyan Lou & Na Ma
Pages: 1641-1651
Published online: 19 Feb 2019
AbstractforRETRACTED ARTICLE: miR-140-5p alleviates the aggressive progression of Wilms’ tumor through directly targeting TGFBR1 gene | PDF (2.7 MB)
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Article
FGG promotes migration and invasion in hepatocellular carcinoma cells through activating epithelial to mesenchymal transition
Xiang Zhang, Fei Wang, Yanbing Huang, Kun Ke, Bixing Zhao, Lihong Chen, Naishun Liao, Lei Wang, Qin Li, Xiaolong Liu, Yingchao Wang & Jingfeng Liu
Pages: 1653-1665
Published online: 19 Feb 2019
AbstractforFGG promotes migration and invasion in hepatocellular carcinoma cells through activating epithelial to mesenchymal transition | Full Text | References | PDF (8 MB) | EPUB
  • 100 Views
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Article
Apoptotic and antimetastatic activities of betulin isolated from Quercus incana against non-small cell lung cancer cells
Binte Zehra, Ayaz Ahmed, Rizwana Sarwar, Ajmal Khan, Umar Farooq, Syed Abid Ali & Ahmed Al-Harrasi
Pages: 1667-1683
Published online: 19 Feb 2019
AbstractforApoptotic and antimetastatic activities of betulin isolated from Quercus incana against non-small cell lung cancer cells | Full Text | References | PDF (9.6 MB) | EPUB
  • 178 Views
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Article
Forskolin exerts anticancer roles in non-Hodgkin’s lymphomas via regulating Axin/β-catenin signaling pathway
Hailei Wang, Chunyan Lou & Na Ma
Pages: 1685-1696
Published online: 19 Feb 2019
AbstractforForskolin exerts anticancer roles in non-Hodgkin’s lymphomas via regulating Axin/β-catenin signaling pathway | Full Text | References | PDF (4.6 MB) | EPUB
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Study Protocol

Article
Laparoscopic uncut Roux-en-Y for radical distal gastrectomy: the study protocol for a multirandomized controlled trial
Quan Wang, Qingrong Ni, Kelu Yang, Sheqing Ji, Yong Fan, Chen Wang, Wenbin Zhang, Su Yan, Qi Ma, Qiuya Wei, Di Zhang, Juan Yu & Gang Ji
Pages: 1697-1704
Published online: 19 Feb 2019
AbstractforLaparoscopic uncut Roux-en-Y for radical distal gastrectomy: the study protocol for a multirandomized controlled trial | Full Text | References | PDF (413.1 KB) | EPUB
  • 68 Views
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Review

Review Article
Optimizing sequential treatment with anti-EGFR and VEGF mAb in metastatic colorectal cancer: current results and controversies
Datian Chen, Kaikai Gu & Huiyu Wang
Pages: 1705-1716
Published online: 19 Feb 2019
AbstractforOptimizing sequential treatment with anti-EGFR and VEGF mAb in metastatic colorectal cancer: current results and controversies | Full Text | References | PDF (198.6 KB) | EPUB
  • 92 Views
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Original Research

Article
C14orf159 suppresses gastric cancer cells’ invasion and proliferation by inactivating ERK signaling
Yan-Mei Zhu, Qiang Li, Xiao-Zhuo Gao, Xiao Meng, Li-Li Sun, Yu Shi, En-Tian Lu & Yong Zhang
Pages: 1717-1723
Published online: 19 Feb 2019
AbstractforC14orf159 suppresses gastric cancer cells’ invasion and proliferation by inactivating ERK signaling | Full Text | References | PDF (4.7 MB) | EPUB
  • 76 Views
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Article
Promising diagnostic and prognostic value of E2Fs in human hepatocellular carcinoma
Yan-Lin Huang, Gang Ning, Lu-Biao Chen, Yi-Fan Lian, Yu-Rong Gu, Jia-Liang Wang, Dong-Mei Chen, Huan Wei & Yue-Hua Huang
Pages: 1725-1740
Published online: 19 Feb 2019
AbstractforPromising diagnostic and prognostic value of E2Fs in human hepatocellular carcinoma | Full Text | References | PDF (3 MB) | EPUB
  • 85 Views
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Article
The prognostic value of Tiam1 correlates with its roles in epithelial–mesenchymal transition progression and angiogenesis in lung adenocarcinoma
Guang Zhu, Yuan Zhang, Qianrong Wang, Shuanlong Che, Yang Yang, Liyan Chen & Zhenhua Lin
Pages: 1741-1752
Published online: 21 Feb 2019
AbstractforThe prognostic value of Tiam1 correlates with its roles in epithelial–mesenchymal transition progression and angiogenesis in lung adenocarcinoma | Full Text | References | PDF (5.2 MB) | EPUB
  • 70 Views
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Article
Cystic brain metastases had slower speed of tumor shrinkage but similar prognosis compared with solid tumors that underwent radiosurgery treatment
Hui Wang, Xiaoye Liu, Xuechao Jiang, Yongchun Song, Xiaoguang Wang, Jingsheng Wang, Yang Dong, Fengtong Li, Zhiqiang Wu, Yuhan Zhang & Zhiyong Yuan
Pages: 1753-1763
Published online: 20 Feb 2019
AbstractforCystic brain metastases had slower speed of tumor shrinkage but similar prognosis compared with solid tumors that underwent radiosurgery treatment | Full Text | References | PDF (2.9 MB) | EPUB
  • 83 Views
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Review

Review Article
Impact of preoperative exercise therapy on surgical outcomes in lung cancer patients with or without COPD: a systematic review and meta-analysis
Xiang Li, Shaolei Li, Shi Yan, Yaqi Wang, Xing Wang, Alan D L Sihoe, Yue Yang & Nan Wu
Pages: 1765-1777
Published online: 20 Feb 2019
AbstractforImpact of preoperative exercise therapy on surgical outcomes in lung cancer patients with or without COPD: a systematic review and meta-analysis | Full Text | References | PDF (744.8 KB) | EPUB
  • 217 Views
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Original Research

Article
lncRNA LINC00460 promoted colorectal cancer cells metastasis via miR-939-5p sponging
Yueyan Zhang, Xingchi Liu, Qiang Li & Yong Zhang
Pages: 1779-1789
Published online: 22 Feb 2019
AbstractforlncRNA LINC00460 promoted colorectal cancer cells metastasis via miR-939-5p sponging | Full Text | References | PDF (7.2 MB) | EPUB
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Letter

Letter
Meta-analysis of the prognostic role of HE4 expression in cancer patients: clinical insights into interpretation of clinical outcomes
Rama Jayaraj & Chellan Kumarasamy
Pages: 1791-1794
Published online: 21 Feb 2019
First Page PreviewforMeta-analysis of the prognostic role of HE4 expression in cancer patients: clinical insights into interpretation of clinical outcomes | Full Text | References | PDF (201 KB) | EPUB
  • 48 Views
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Original Research

Article
E3 ubiquitin ligase Smurf2: a prognostic factor in microsatellite stable colorectal cancer
Fee Klupp, Christina Giese, Niels Halama, Clemens Franz, Felix Lasitschka, Arne Warth, Thomas Schmidt, Matthias Kloor, Alexis Ulrich & Martin Schneider
Pages: 1795-1803
Published online: 22 Feb 2019
AbstractforE3 ubiquitin ligase Smurf2: a prognostic factor in microsatellite stable colorectal cancer | Full Text | References | PDF (1.5 MB) | EPUB
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Article
miR-491-5p functions as a tumor suppressor by targeting IGF2 in colorectal cancer
Lei Lu, Ming Cai, Meixia Peng, Fei Wang & Xiaofeng Zhai
Pages: 1805-1816
Published online: 22 Feb 2019
AbstractformiR-491-5p functions as a tumor suppressor by targeting IGF2 in colorectal cancer | Full Text | References | PDF (5.2 MB) | EPUB
  • 72 Views
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Review

Review Article
Progress in immunocytochemical staining for cervical cancer screening
Hengzi Sun, Keng Shen & Dongyan Cao
Pages: 1817-1827
Published online: 22 Feb 2019
AbstractforProgress in immunocytochemical staining for cervical cancer screening | Full Text | References | PDF (754.4 KB) | EPUB
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Review Article
Oncometabolites as biomarkers in thyroid cancer: a systematic review
Fatemeh Khatami, Moloud Payab, Masoumeh Sarvari, Kambiz Gilany, Bagher Larijani, Babak Arjmand & Seyed Mohammad Tavangar
Pages: 1829-1841
Published online: 25 Feb 2019
AbstractforOncometabolites as biomarkers in thyroid cancer: a systematic review | Full Text | References | PDF (702 KB) | EPUB
  • 289 Views
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Review Article
The unique invasiveness of glioblastoma and possible drug targets on extracellular matrix
Adam Hatoum, Raihan Mohammed & Omar Zakieh
Pages: 1843-1855
Published online: 25 Feb 2019
AbstractforThe unique invasiveness of glioblastoma and possible drug targets on extracellular matrix | Full Text | References | PDF (1.5 MB) | EPUB
  • 277 Views
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Original Research

Article
KIF15 promotes bladder cancer proliferation via the MEK–ERK signaling pathway
Hongda Zhao, Qiyu Bo, Zonglong Wu, Qinggang Liu, Yan Li, Ning Zhang, Hu Guo & Benkang Shi
Pages: 1857-1868
Published online: 26 Feb 2019
AbstractforKIF15 promotes bladder cancer proliferation via the MEK–ERK signaling pathway | Full Text | References | PDF (5.6 MB) | EPUB
  • 108 Views
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Article
INTS8 accelerates the epithelial-to-mesenchymal transition in hepatocellular carcinoma by upregulating the TGF-β signaling pathway
Hui Tong, Xiaohui Liu, Tao Li, Weihua Qiu, Chenghong Peng, Baiyong Shen & Zhecheng Zhu
Pages: 1869-1879
Published online: 26 Feb 2019
AbstractforINTS8 accelerates the epithelial-to-mesenchymal transition in hepatocellular carcinoma by upregulating the TGF-β signaling pathway | Full Text | References | PDF (9.2 MB) | EPUB
  • 65 Views
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Review

Review Article
Meta-analysis of the prognostic value of C-C chemokine receptor type 7 in patients with solid tumors
Guangchen Zu, Baoyang Luo, Yong Yang, Yuwei Tan, Tianyu Tang, Yue Zhang, Xuemin Chen & Donglin Sun
Pages: 1881-1892
Published online: 26 Feb 2019
AbstractforMeta-analysis of the prognostic value of C-C chemokine receptor type 7 in patients with solid tumors | Full Text | References | PDF (934.1 KB) | EPUB
  • 60 Views
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Original Research

Article
Interferon α-inducible protein 27 is an oncogene and highly expressed in cholangiocarcinoma patients with poor survival
Kun-Chun Chiang, Sheng-Teng Huang, Ren-Chin Wu, Shih-Chiang Huang, Ta-Sen Yeh, Ming-Huang Chen, Jun-Te Hsu, Li-Wei Chen, Sheng-Fong Kuo, Ho-Yen Chueh, Horng-Heng Juang, Shuen-Iu Hung, Chun-Nan Yeh & Jong-Hwei S Pang
Pages: 1893-1905
Published online: 28 Feb 2019
AbstractforInterferon α-inducible protein 27 is an oncogene and highly expressed in cholangiocarcinoma patients with poor survival | Full Text | References | PDF (3.1 MB) | EPUB
  • 74 Views
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Article
Pretreatment lymphocyte-to-monocyte ratio as a predictor of survival among patients with ovarian cancer: a meta-analysis
Xu-ping Gao, Yan-hua Liu, Ze-ying Liu, Li-jun Wang, Chun-xia Jing, Sui Zhu & Fang-fang Zeng
Pages: 1907-1920
Published online: 27 Feb 2019
AbstractforPretreatment lymphocyte-to-monocyte ratio as a predictor of survival among patients with ovarian cancer: a meta-analysis | Full Text | References | PDF (712.4 KB) | EPUB
  • 101 Views
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Review

Review Article
The role and diagnostic potential of gastrokine 1 in gastric cancer
Olga M Koper-Lenkiewicz, Joanna Kamińska, Beata Gawrońska & Joanna Matowicka-Karna
Pages: 1921-1931
Published online: 01 Mar 2019
AbstractforThe role and diagnostic potential of gastrokine 1 in gastric cancer | Full Text | References | PDF (2 MB) | EPUB
  • 81 Views
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Original Research

Article
Pancreatic neuroendocrine tumor: prediction of the tumor grade using magnetic resonance imaging findings and texture analysis with 3-T magnetic resonance
Chuan-gen Guo, Shuai Ren, Xiao Chen, Qi-dong Wang, Wen-bo Xiao, Jing-feng Zhang, Shao-feng Duan & Zhong-qiu Wang
Pages: 1933-1944
Published online: 04 Mar 2019
AbstractforPancreatic neuroendocrine tumor: prediction of the tumor grade using magnetic resonance imaging findings and texture analysis with 3-T magnetic resonance | Full Text | References | PDF (2 MB) | EPUB
  • 164 Views
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Article
EGFR mutations are significantly associated with visceral pleural invasion development in non-small-cell lung cancer patients
Jinghan Shi, Yang Yang, Yanfeng Zhao, Junjie Zhu, Xiao Song & Gening Jiang
Pages: 1945-1957
Published online: 01 Mar 2019
AbstractforEGFR mutations are significantly associated with visceral pleural invasion development in non-small-cell lung cancer patients | Full Text | References | PDF (1.2 MB) | EPUB
  • 60 Views
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Article
Increased cancer risk after myocardial infarction: fact or fiction? A systemic review and meta-analysis
Na Li, Zhigang Huang, Yanda Zhang, Haitao Sun, Jiamei Wang & Jian Zhao
Pages: 1959-1968
Published online: 01 Mar 2019
AbstractforIncreased cancer risk after myocardial infarction: fact or fiction? A systemic review and meta-analysis | Full Text | References | PDF (858.7 KB) | EPUB
  • 80 Views
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Article
Second primary malignancy in patients with cholangiocarcinoma: a population-based study
Liping Zhuang, Xia Yan & Zhiqiang Meng
Pages: 1969-1983
Published online: 01 Mar 2019
AbstractforSecond primary malignancy in patients with cholangiocarcinoma: a population-based study | Full Text | References | PDF (1.6 MB) | EPUB
  • 70 Views
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Article
A novel 4-gene prognostic signature for hypermutated colorectal cancer
Weiting Ge, Wen Cai, Rui Bai, Wangxiong Hu, Dehao Wu, Shu Zheng & Hanguang Hu
Pages: 1985-1996
Published online: 04 Mar 2019
AbstractforA novel 4-gene prognostic signature for hypermutated colorectal cancer | Full Text | References | PDF (941 KB) | EPUB
  • 94 Views
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Article
Upregulated circ RNA hsa_circ_0000337 promotes cell proliferation, migration, and invasion of esophageal squamous cell carcinoma
Huan Song, Dian Xu, Peiyi Shi, Biyu He, Zhongqi Li, Ye Ji, Charles Kwaku Agbeko & Jianming Wang
Pages: 1997-2006
Published online: 04 Mar 2019
AbstractforUpregulated circ RNA hsa_circ_0000337 promotes cell proliferation, migration, and invasion of esophageal squamous cell carcinoma | Full Text | References | PDF (3.6 MB) | EPUB
  • 85 Views
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Article
Outcomes of gastrectomy following upfront chemotherapy in advanced gastric cancer patients with a single noncurable factor: a cohort study
Wei Li, Huiqin Jiang, Yiyi Yu, Yan Wang, Zhiming Wang, Yuehong Cui, Kuntang Shen, Zhenbin Shen, Yong Fang & Tianshu Liu
Pages: 2007-2013
Published online: 05 Mar 2019
AbstractforOutcomes of gastrectomy following upfront chemotherapy in advanced gastric cancer patients with a single noncurable factor: a cohort study | Full Text | References | PDF (501 KB) | EPUB
  • 59 Views
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Article
CIRP regulates BEV-induced cell migration in gliomas
Yu-Xiao Liu, Jun-Nian Zhou, Ke-Hui Liu, Xiang-pin Fu, Zhi-Wen Zhang, Qin-Hong Zhang & Wen Yue
Pages: 2015-2025
Published online: 11 Mar 2019
AbstractforCIRP regulates BEV-induced cell migration in gliomas | Full Text | References | PDF (6.9 MB) | EPUB
  • 75 Views
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Article
Meta-analysis of the prognostic value of lncRNA DANCR for cancer patients in China
Yanghua Fan, Yu He, Xi Zhou, Yong Liu & Fu Wang
Pages: 2027-2037
Published online: 05 Mar 2019
AbstractforMeta-analysis of the prognostic value of lncRNA DANCR for cancer patients in China | Full Text | References | PDF (2.2 MB) | EPUB
  • 62 Views
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Article
MicroRNA-21 and microRNA-30c as diagnostic biomarkers for prostate cancer: a meta-analysis
Hongxing Zhou & Xuming Zhu
Pages: 2039-2050
Published online: 06 Mar 2019
AbstractforMicroRNA-21 and microRNA-30c as diagnostic biomarkers for prostate cancer: a meta-analysis | Full Text | References | PDF (1.7 MB) | EPUB
  • 91 Views
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Article
Cervical cancer in women aged 25 years or younger: a retrospective study
Yujia Kong, Liju Zong, Junjun Yang, Ming Wu & Yang Xiang
Pages: 2051-2058
Published online: 06 Mar 2019
AbstractforCervical cancer in women aged 25 years or younger: a retrospective study | Full Text | References | PDF (365.3 KB) | EPUB
  • 392 Views
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Article
Long noncoding RNA H19 is a critical oncogenic driver and contributes to epithelial-mesenchymal transition in papillary thyroid carcinoma
Wei-Quan Liang, De Zeng, Chun-Fa Chen, Shu-Ming Sun, Xiao-Feng Lu, Chun-yan Peng & Hao-Yu Lin
Pages: 2059-2072
Published online: 06 Mar 2019
AbstractforLong noncoding RNA H19 is a critical oncogenic driver and contributes to epithelial-mesenchymal transition in papillary thyroid carcinoma | Full Text | References | PDF (5.1 MB) | EPUB
  • 60 Views
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Article
Nonspecific immunoglobulin G is effective in preventing and treating cancer in mice
Qian Xu, Zaiping Zhang, Zhiming Chen, Biying Zhang, Chanyuan Zhao, Yimin Zhang, Conghui Zhao, Xiaodong Deng, Yao Zhou, Yanyun Wu & Jiang Gu
Pages: 2073-2085
Published online: 07 Mar 2019
AbstractforNonspecific immunoglobulin G is effective in preventing and treating cancer in mice | Full Text | References | PDF (3.9 MB) | EPUB
  • 92 Views
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Article
Construction of a GLUT-1 and HIF-1α gene knockout cell model in HEp-2 cells using the CRISPR/Cas9 technique
Zhong-Jie Lu, Qi Yu, Shui-Hong Zhou, Jun Fan, Li-Fang Shen, Yang-Yang Bao, Ting-Ting Wu, Min-Li Zhou & Ya-Ping Huang
Pages: 2087-2096
Published online: 08 Mar 2019
AbstractforConstruction of a GLUT-1 and HIF-1α gene knockout cell model in HEp-2 cells using the CRISPR/Cas9 technique | Full Text | References | PDF (5.8 MB) | EPUB
  • 99 Views
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Commentary

Article Commentary
Axillary management still needed for patients with sentinel node micrometastases
Bin-Bin Cong, Jin-Ming Yu & Yong-Sheng Wang
Pages: 2097-2100
Published online: 08 Mar 2019
AbstractforAxillary management still needed for patients with sentinel node micrometastases | Full Text | References | PDF (280.7 KB) | EPUB
  • 77 Views
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Original Research

Article
Decentralized colorectal cancer care in Germany over the last decade is associated with high in-hospital morbidity and mortality
Tarik Ghadban, Matthias Reeh, Maximilian Bockhorn, Rainer Grotelueschen, Kai Bachmann, Katharina Grupp, Faik G Uzunoglu, Jakob R Izbicki & Daniel R Perez
Pages: 2101-2107
Published online: 12 Mar 2019
AbstractforDecentralized colorectal cancer care in Germany over the last decade is associated with high in-hospital morbidity and mortality | Full Text | References | PDF (805.9 KB) | EPUB
  • 71 Views
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Article
DR7 encoded by human herpesvirus 6 promotes glioma development and progression
Bin Gu, Meng Li, Yan Zhang, Lingyun Li, Kun Yao & Shizhi Wang
Pages: 2109-2118
Published online: 12 Mar 2019
AbstractforDR7 encoded by human herpesvirus 6 promotes glioma development and progression | Full Text | References | PDF (3 MB) | EPUB
  • 77 Views
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Article
Evolution of the chemotherapeutic landscape and survival outcome in patients with metastatic pancreatic cancer: a four-institute cohort study in Taiwan, 2010–2016
Wen-Chi Chou, Yen-Yang Chen, Chia-Yen Hung, Jen-Shi Chen, Chang-Hsien Lu & Pei-Hung Chang
Pages: 2119-2127
Published online: 14 Mar 2019
AbstractforEvolution of the chemotherapeutic landscape and survival outcome in patients with metastatic pancreatic cancer: a four-institute cohort study in Taiwan, 2010–2016 | Full Text | References | PDF (837.6 KB) | EPUB
  • 59 Views
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Article
Comparing the efficacy of concurrent EGFR-TKI and whole-brain radiotherapy vs EGFR-TKI alone as a first-line therapy for advanced EGFR-mutated non-small-cell lung cancer with brain metastases: a retrospective cohort study
Zhi-Yong He, Mei-Fang Li, Jing-Hui Lin, Dong Lin & Ren-Jang Lin
Pages: 2129-2138
Published online: 14 Mar 2019
AbstractforComparing the efficacy of concurrent EGFR-TKI and whole-brain radiotherapy vs EGFR-TKI alone as a first-line therapy for advanced EGFR-mutated non-small-cell lung cancer with brain metastases: a retrospective cohort study | Full Text | References | PDF (668 KB) | EPUB
  • 93 Views
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Article
Oncogenic role of ABHD5 in endometrial cancer
Qing Zhou, Fang Wang, Kai Zhou, Kate Huang, Qiuyuan Zhu, Xishao Luo, Jiangtao Yu & Zhengzheng Shi
Pages: 2139-2150
Published online: 14 Mar 2019
AbstractforOncogenic role of ABHD5 in endometrial cancer | Full Text | References | PDF (3.8 MB) | EPUB
  • 65 Views
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Review

Review Article
State of the art for gastric signet ring cell carcinoma: from classification, prognosis, and genomic characteristics to specified treatments
Julita Machlowska, Małgorzata Pucułek, Monika Sitarz, Paweł Terlecki, Ryszard Maciejewski & Robert Sitarz
Pages: 2151-2161
Published online: 15 Mar 2019
AbstractforState of the art for gastric signet ring cell carcinoma: from classification, prognosis, and genomic characteristics to specified treatments | Full Text | References | PDF (969.1 KB) | EPUB
  • 253 Views
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Original Research

Article
A multicenter study of a contrast-enhanced ultrasound diagnostic classification of breast lesions
Lina Tang, Yijie Chen, Zhongshi Du, Zhaoming Zhong, Qin Chen, Lichun Yang, Ruoxia Shen, Yan Cheng, Zizhen Zhang, Ehui Han, Zhihong Lv, Lijun Yuan, Yong Yang, Yinrong Cheng, Lei Yang, Shengli Wang, Baoyan Bai & Jun Luo
Pages: 2163-2170
Published online: 15 Mar 2019
AbstractforA multicenter study of a contrast-enhanced ultrasound diagnostic classification of breast lesions | Full Text | References | PDF (2.8 MB) | EPUB
  • 131 Views
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Article
Etiology and management of nasopharyngeal hemorrhage after radiotherapy for nasopharyngeal carcinoma
Jiabin Zhan, Shuai Zhang, Xin Wei, Yihui Fu & Jing Zheng
Pages: 2171-2178
Published online: 15 Mar 2019
AbstractforEtiology and management of nasopharyngeal hemorrhage after radiotherapy for nasopharyngeal carcinoma | Full Text | References | PDF (4.3 MB) | EPUB
  • 125 Views
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Article
The oncogenic role of GNL3 in the progression and metastasis of osteosarcoma
Tianyou Li, Long Li, Xiangyu Wu, Kaixuan Tian & Yanzhou Wang
Pages: 2179-2188
Published online: 15 Mar 2019
AbstractforThe oncogenic role of GNL3 in the progression and metastasis of osteosarcoma | Full Text | References | PDF (7.3 MB) | EPUB
  • 71 Views
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Article
Defining unmet clinical need across the pathway of brain tumor care: a patient and carer perspective
William Sage, Rocío Fernández-Méndez, Anna Crofton, Michael J Gifford, Alexey Bannykh, Constantinos Chrysaphinis, Emma Tingley, Helen Bulbeck, Mita Brahmbhatt, John D Pickard, Fiona M Walter, Andrew Brodbelt, Stephen J Price & Alexis J Joannides
Pages: 2189-2202
Published online: 19 Mar 2019
AbstractforDefining unmet clinical need across the pathway of brain tumor care: a patient and carer perspective | Full Text | References | PDF (487.6 KB) | EPUB
  • 100 Views
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Article
Increased expression of TMED2 is an unfavorable prognostic factor in patients with breast cancer
Xia Lin, Jian Liu, Shu Fang Hu & Xun Hu
Pages: 2203-2214
Published online: 18 Mar 2019
AbstractforIncreased expression of TMED2 is an unfavorable prognostic factor in patients with breast cancer | Full Text | References | PDF (725.7 KB) | EPUB
  • 68 Views
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Article
Suppressed OGT expression inhibits cell proliferation and modulates EGFR expression in renal cell carcinoma
Longsheng Wang, Shaojun Chen, Junfeng Zhang, Shiyu Mao, Weipu Mao, Wentao Zhang, Yadong Guo, Yuan Wu, Ruiliang Wang, Yang Yan & Xudong Yao
Pages: 2215-2223
Published online: 19 Mar 2019
AbstractforSuppressed OGT expression inhibits cell proliferation and modulates EGFR expression in renal cell carcinoma | Full Text | References | PDF (6 MB) | EPUB
  • 76 Views
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Article
Nutritional status and related factors of patients with advanced lung cancer in northern China: a retrospective study
Ting Ge, Tie Lin, Jing Yang & Meng Wang
Pages: 2225-2231
Published online: 19 Mar 2019
AbstractforNutritional status and related factors of patients with advanced lung cancer in northern China: a retrospective study | Full Text | References | PDF (689.8 KB) | EPUB
  • 193 Views
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Article
Low-dose of olanzapine has ameliorating effects on cancer-related anorexia
Hideki Okamoto, Koyo Shono & Natsuko Nozaki-Taguchi
Pages: 2233-2239
Published online: 19 Mar 2019
AbstractforLow-dose of olanzapine has ameliorating effects on cancer-related anorexia | Full Text | References | PDF (568.8 KB) | EPUB
  • 173 Views
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Review

Review Article
Management of mycosis fungoides-type cutaneous T-cell lymphoma (MF-CTCL): focus on chlormethine gel
Daphné Denis, Nathalie Beneton, Kamel Laribi & Hervé Maillard
Pages: 2241-2251
Published online: 20 Mar 2019
AbstractforManagement of mycosis fungoides-type cutaneous T-cell lymphoma (MF-CTCL): focus on chlormethine gel | Full Text | References | PDF (1.6 MB) | EPUB
  • 175 Views
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Original Research

Article
Influence of thoracic drainage fluid on proliferation, migration, apoptosis, and drug resistance in lung cancer cell lines
Yuqiang Mao, Ying Yu & Yun Han
Pages: 2253-2259
Published online: 20 Mar 2019
AbstractforInfluence of thoracic drainage fluid on proliferation, migration, apoptosis, and drug resistance in lung cancer cell lines | Full Text | References | PDF (3.4 MB) | EPUB
  • 62 Views
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Article
Is ramucirumab and paclitaxel therapy beneficial for second-line treatment of metastatic gastric or junctional adenocarcinoma for patients with ascites? Analysis of RAINBOW phase 3 trial data
Kei Muro, Min-Hua Jen & Rebecca Cheng
Pages: 2261-2267
Published online: 20 Mar 2019
AbstractforIs ramucirumab and paclitaxel therapy beneficial for second-line treatment of metastatic gastric or junctional adenocarcinoma for patients with ascites? Analysis of RAINBOW phase 3 trial data | Full Text | References | PDF (208.3 KB) | EPUB
  • 115 Views
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Article
Primary tumor location is an important predictor of survival in pulmonary adenocarcinoma
Zhe Wang, Minghuan Li, Feifei Teng, Li Kong & Jinming Yu
Pages: 2269-2280
Published online: 21 Mar 2019
AbstractforPrimary tumor location is an important predictor of survival in pulmonary adenocarcinoma | Full Text | References | PDF (704.7 KB) | EPUB
  • 102 Views
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Article
Role of the pretreatment neutrophil-to-lymphocyte ratio in the survival of primary parotid cancer patients
Guangyan Cheng, Fei Liu, Xinyu Niu & Qigen Fang
Pages: 2281-2286
Published online: 21 Mar 2019
AbstractforRole of the pretreatment neutrophil-to-lymphocyte ratio in the survival of primary parotid cancer patients | Full Text | References | PDF (306.3 KB) | EPUB
  • 54 Views
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Review

Review Article
Natural gypenosides: targeting cancer through different molecular pathways
Bashir Ahmad, Suliman Khan, Ghulam Nabi, Yaser Gamallat, Pengyu Su, Yazeed Jamalat, Pengfei Duan & Lunguang Yao
Pages: 2287-2297
Published online: 27 Mar 2019
AbstractforNatural gypenosides: targeting cancer through different molecular pathways | Full Text | References | PDF (473.2 KB) | EPUB
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Original Research

Article
PF4V1, an miRNA-875-3p target, suppresses cell proliferation, migration, and invasion in prostate cancer and serves as a potential prognostic biomarker
Dongyang Li, Xuanyu Hao, Yudi Dong, Mo Zhang & Yongsheng Song
Pages: 2299-2312
Published online: 21 Mar 2019
AbstractforPF4V1, an miRNA-875-3p target, suppresses cell proliferation, migration, and invasion in prostate cancer and serves as a potential prognostic biomarker | Full Text | References | PDF (11.4 MB) | EPUB
  • 106 Views
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Article
The impact of the interval between the induction of chemotherapy and radiotherapy on the survival of patients with nasopharyngeal carcinoma
Shiping Yang, Xiaoling Fu, Guang Huang, Junni Chen, Shishi Luo, Zhenping Wang, Fanzhong Kong, Gang Wu, Shaomin Lin, Fen Wang & Longhua Chen
Pages: 2313-2320
Published online: 22 Mar 2019
AbstractforThe impact of the interval between the induction of chemotherapy and radiotherapy on the survival of patients with nasopharyngeal carcinoma | Full Text | References | PDF (512.5 KB) | EPUB
  • 66 Views
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Review

Review Article
A systematic review of international guidelines and recommendations for the genetic screening, diagnosis, genetic counseling, and treatment of BRCA-mutated breast cancer
Carol Forbes, Debra Fayter, Shelley de Kock & Ruben GW Quek
Pages: 2321-2337
Published online: 22 Mar 2019
AbstractforA systematic review of international guidelines and recommendations for the genetic screening, diagnosis, genetic counseling, and treatment of BRCA-mutated breast cancer | Full Text | References | PDF (295.3 KB) | EPUB
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Original Research

Article
UNBS5162 and amonafide inhibits tumor progression in human melanoma by the AKT/mTOR pathway
Yingyi Ye, Shuhong Huang & Yingying Wu
Pages: 2339-2348
Published online: 22 Mar 2019
AbstractforUNBS5162 and amonafide inhibits tumor progression in human melanoma by the AKT/mTOR pathway | Full Text | References | PDF (8.7 MB) | EPUB
  • 59 Views
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Article
Linc01194 acts as an oncogene in colorectal carcinoma and is associated with poor survival outcome
Xiaoxue Wang, Zhimin Liu, Hong Tong, Hui Peng, Zhenyu Xian, Li Li, Bang Hu & Shangkui Xie
Pages: 2349-2362
Published online: 22 Mar 2019
AbstractforLinc01194 acts as an oncogene in colorectal carcinoma and is associated with poor survival outcome | Full Text | References | PDF (4 MB) | EPUB
  • 62 Views
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Article
Comparison of transcriptional profiles in human lymphocyte cells irradiated with 12C ion beams at 0–2.0 Gy
Ruifeng Zhang, Xuhong Dang, Zhongxin Zhang, Yayi Yuan, Yue Ren, Zhikai Duan & Yahui Zuo
Pages: 2363-2369
Published online: 22 Mar 2019
AbstractforComparison of transcriptional profiles in human lymphocyte cells irradiated with 12C ion beams at 0–2.0 Gy | Full Text | References | PDF (398.9 KB) | EPUB
  • 55 Views
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Article
Clinicopathological characteristics and recurrence risk of papillary thyroid microcarcinoma in the elderly
Xiaofei Wang, Jianyong Lei, Tao Wei, Jingqiang Zhu & Zhihui Li
Pages: 2371-2377
Published online: 25 Mar 2019
AbstractforClinicopathological characteristics and recurrence risk of papillary thyroid microcarcinoma in the elderly | Full Text | References | PDF (294.5 KB) | EPUB
  • 64 Views
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Article
ITLNI identified by comprehensive bioinformatic analysis as a hub candidate biological target in human epithelial ovarian cancer
JinHui Liu, SiYue Li, JunYa Liang, Yi Jiang, YiCong Wan, ShuLin Zhou & WenJun Cheng
Pages: 2379-2392
Published online: 25 Mar 2019
AbstractforITLNI identified by comprehensive bioinformatic analysis as a hub candidate biological target in human epithelial ovarian cancer | Full Text | References | PDF (4.6 MB) | EPUB
  • 84 Views
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Review

Review Article
Chimeric antigen receptor (CAR) T-cell therapy as a treatment option for patients with B-cell lymphomas: perspectives on the therapeutic potential of Axicabtagene ciloleucel
Andreas Viardot, Verena Wais, Elisa Sala & Sixten Koerper
Pages: 2393-2404
Published online: 25 Mar 2019
AbstractforChimeric antigen receptor (CAR) T-cell therapy as a treatment option for patients with B-cell lymphomas: perspectives on the therapeutic potential of Axicabtagene ciloleucel | Full Text | References | PDF (289.1 KB) | EPUB
  • 134 Views
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Review Article
The role of Clusterin in cancer metastasis
Mei Peng, Jun Deng, Sichun Zhou, Ting Tao, Qiongli Su, Xue Yang & Xiaoping Yang
Pages: 2405-2414
Published online: 27 Mar 2019
AbstractforThe role of Clusterin in cancer metastasis | Full Text | References | PDF (623.1 KB) | EPUB
  • 141 Views
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Original Research

Article
RETRACTED ARTICLE: WFDC2 contributes to epithelial–mesenchymal transition (EMT) by activating AKT signaling pathway and regulating MMP-2 expression
Yao Chen, Liping Huang, Suihai Wang, Ji-Liang Li, Ming Li, Yingsong Wu & Tiancai Liu
Pages: 2415-2424
Published online: 27 Mar 2019
AbstractforRETRACTED ARTICLE: WFDC2 contributes to epithelial–mesenchymal transition (EMT) by activating AKT signaling pathway and regulating MMP-2 expression | PDF (664.2 KB)
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Article
Epigallocatechin-3-gallate-induced vascular normalization in A549-cell xenograft-bearing nude mice: therapeutic efficacy in combination with chemotherapy
Pengbo Deng, Chengping Hu, Zeng Xiong, Yuanyuan Li, Juan Jiang, Huaping Yang, Yongjun Tang, Liming Cao & Rongli Lu
Pages: 2425-2439
Published online: 27 Mar 2019
AbstractforEpigallocatechin-3-gallate-induced vascular normalization in A549-cell xenograft-bearing nude mice: therapeutic efficacy in combination with chemotherapy | Full Text | References | PDF (7.3 MB) | EPUB
  • 93 Views
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Does every classical type of well-differentiated thyroid cancer have excellent prognosis? A case series and literature review
Krzysztof Kaliszewski
Pages: 2441-2448
Published online: 01 Apr 2019
AbstractforDoes every classical type of well-differentiated thyroid cancer have excellent prognosis? A case series and literature review | Full Text | References | PDF (418.4 KB) | EPUB
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Article
S100A16 regulated by Snail promotes the chemoresistance of nonmuscle invasive bladder cancer through the AKT/Bcl-2 pathway
Chanjuan Wang, Xi Zhu, Aiwei Li, Shuo Yang, Rui Qiao & Jie Zhang
Pages: 2449-2456
Published online: 27 Mar 2019
AbstractforS100A16 regulated by Snail promotes the chemoresistance of nonmuscle invasive bladder cancer through the AKT/Bcl-2 pathway | Full Text | References | PDF (443.1 KB) | EPUB
  • 75 Views
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Article
JAM3 functions as a novel tumor suppressor and is inactivated by DNA methylation in colorectal cancer
Dan Zhou, Weiwei Tang, Yun Zhang & Han-Xiang An
Pages: 2457-2470
Published online: 27 Mar 2019
AbstractforJAM3 functions as a novel tumor suppressor and is inactivated by DNA methylation in colorectal cancer | Full Text | References | PDF (8.4 MB) | EPUB
  • 118 Views
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Article
Nomogram for predicting disease-free survival among a multicenter cohort of Chinese patients with locally advanced rectal cancer
Zhen-Hui Li, Pei-Yi Xie, Da-Fu Zhang, Ya-Jun Li, Lin Wu, Jian Dong, Jian Xiao & Zai-Yi Liu
Pages: 2471-2483
Published online: 29 Mar 2019
AbstractforNomogram for predicting disease-free survival among a multicenter cohort of Chinese patients with locally advanced rectal cancer | Full Text | References | PDF (447.8 KB) | EPUB
  • 62 Views
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Article
LAPTM4B facilitates tumor growth and induces autophagy in hepatocellular carcinoma
Fei Wang, Huita Wu, Sheng Zhang, Jing Lu, Yuyan Lu, Ping Zhan, Qinliang Fang, Fuqiang Wang, Xiuming Zhang, Chengrong Xie & Zhenyu Yin
Pages: 2485-2497
Published online: 27 Mar 2019
AbstractforLAPTM4B facilitates tumor growth and induces autophagy in hepatocellular carcinoma | Full Text | References | PDF (938.1 KB) | EPUB
  • 74 Views
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Article
Effect of ultrasound-guided proximal and distal approach for obturator nerve block in transurethral resection of bladder cancer under spinal anesthesia
Chao Han, Tieliang Ma, Daoyun Lei, Songhui Xie & Zhijun Ge
Pages: 2499-2505
Published online: 27 Mar 2019
AbstractforEffect of ultrasound-guided proximal and distal approach for obturator nerve block in transurethral resection of bladder cancer under spinal anesthesia | Full Text | References | PDF (437.1 KB) | EPUB
  • 99 Views
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Article
Positive or close margins: reoperation rate and second conservative resection or total mastectomy?
Gilles Houvenaeghel, Eric Lambaudie, Marie Bannier, Sandrine Rua, Julien Barrou, Mellie Heinemann, Max Buttarelli, Jeanne Thomassin Piana & Monique Cohen
Pages: 2507-2516
Published online: 28 Mar 2019
AbstractforPositive or close margins: reoperation rate and second conservative resection or total mastectomy? | Full Text | References | PDF (220.4 KB) | EPUB
  • 105 Views
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Article
Cadherin-11 is inactivated due to promoter methylation and functions in colorectal cancer as a tumour suppressor
Shiyun Yuan, Lin Li, Shili Xiang, Hexun Jia & Tao Luo
Pages: 2517-2529
Published online: 28 Mar 2019
AbstractforCadherin-11 is inactivated due to promoter methylation and functions in colorectal cancer as a tumour suppressor | Full Text | References | PDF (854 KB) | EPUB
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Article
RETRACTED ARTICLE: microRNA-944 inhibits the malignancy of hepatocellular carcinoma by directly targeting IGF-1R and deactivating the PI3K/Akt signaling pathway
Lili Lv, Xiaodong Wang & Tonghui Ma
Pages: 2531-2543
Published online: 29 Mar 2019
AbstractforRETRACTED ARTICLE: microRNA-944 inhibits the malignancy of hepatocellular carcinoma by directly targeting IGF-1R and deactivating the PI3K/Akt signaling pathway | PDF (1.1 MB)
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Article
Clinical value of ROMA index in diagnosis of ovarian cancer: meta-analysis
Ranliang Cui, Yichao Wang, Ying Li & Yueguo Li
Pages: 2545-2551
Published online: 28 Mar 2019
AbstractforClinical value of ROMA index in diagnosis of ovarian cancer: meta-analysis | Full Text | References | PDF (1.1 MB) | EPUB
  • 307 Views
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Article
Clinical features and prognostic factors of primary bone marrow lymphoma
Gangjian Wang, Yu Chang, Xiaolong Wu, Xin Li, Ling Li, Lei Zhang, Xiaorui Fu, Zhenchang Sun, Xudong Zhang & Mingzh Zhang
Pages: 2553-2563
Published online: 29 Mar 2019
AbstractforClinical features and prognostic factors of primary bone marrow lymphoma | Full Text | References | PDF (285.4 KB) | EPUB
  • 102 Views
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Article
NECTIN4 promotes papillary thyroid cancer cell proliferation, migration, and invasion and triggers EMT by activating AKT
Ru-Tian Hao, Chen Zheng, Chen-Yong Wu, Er-Jie Xia, Xiao-Fen Zhou, Rui-Da Quan & Xiao-Hua Zhang
Pages: 2565-2578
Published online: 02 Apr 2019
AbstractforNECTIN4 promotes papillary thyroid cancer cell proliferation, migration, and invasion and triggers EMT by activating AKT | Full Text | References | PDF (1.1 MB) | EPUB
  • 145 Views
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Article
L3 skeletal muscle index (L3SMI) is a surrogate marker of sarcopenia and frailty in non-small cell lung cancer patients
D Portal, L Hofstetter, I Eshed, C Dan-Lantsman, T Sella, D Urban, A Onn, J Bar & G Segal
Pages: 2579-2588
Published online: 01 Apr 2019
AbstractforL3 skeletal muscle index (L3SMI) is a surrogate marker of sarcopenia and frailty in non-small cell lung cancer patients | Full Text | References | PDF (359 KB) | EPUB
  • 149 Views
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Article
CIP2A overexpression in Taiwanese oral cancer patients
Bharath Kumar Velmurugan, Hsin-Kai Wang, Chia-Min Chung, Chien-Hsun Lee, Lan-Ru Huang, Kun-Tu Yeh & Shu-Hui Lin
Pages: 2589-2594
Published online: 05 Apr 2019
AbstractforCIP2A overexpression in Taiwanese oral cancer patients | Full Text | References | PDF (278.3 KB) | EPUB
  • 77 Views
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Article
Comparison of irisin hormone expression between thyroid cancer tissues and oncocytic variant cells
Kader Ugur, Suleyman Aydin, Tuncay Kuloglu, Gokhan Artas, Mehmet Ali Kocdor, İbrahim Sahin, Meltem Yardim & İbrahim Hanefi Ozercan
Pages: 2595-2603
Published online: 28 Mar 2019
AbstractforComparison of irisin hormone expression between thyroid cancer tissues and oncocytic variant cells | Full Text | References | PDF (1.4 MB) | EPUB
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Article
HLA-DQB1 expression on tumor cells is a novel favorable prognostic factor for relapse in early-stage lung adenocarcinoma
Liang Zhang, Mengxia Li, Bo Deng, Nan Dai, Yan Feng, Jinlu Shan, Yuxin Yang, Chengyi Mao, Ping Huang, Chengxiong Xu & Dong Wang
Pages: 2605-2616
Published online: 01 Apr 2019
AbstractforHLA-DQB1 expression on tumor cells is a novel favorable prognostic factor for relapse in early-stage lung adenocarcinoma | Full Text | References | PDF (894.3 KB) | EPUB
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Article
Repeat procedures for recurrent colorectal liver metastases: analysis of long-term liver regeneration and outcome
Valentinus T Valdimarsson, Katarina Hellberg, Torkel B Brismar, Ernesto Sparrelid & Christian Sturesson
Pages: 2617-2622
Published online: 05 Apr 2019
AbstractforRepeat procedures for recurrent colorectal liver metastases: analysis of long-term liver regeneration and outcome | Full Text | References | PDF (284.9 KB) | EPUB
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Review

Review Article
Biliary tract cancers: current knowledge, clinical candidates and future challenges
Noor-ul-Ain Tariq, Mairéad G McNamara & Juan W Valle
Pages: 2623-2642
Published online: 29 Mar 2019
AbstractforBiliary tract cancers: current knowledge, clinical candidates and future challenges | Full Text | References | PDF (1.7 MB) | EPUB
  • 197 Views
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Original Research

Article
Inhibition of human glioblastoma cell invasion involves PION@E6 mediated autophagy process
Zhongyu Ren, Jing Liang, Peng Zhang, Jianjiao Chen & Jian Wen
Pages: 2643-2652
Published online: 29 Mar 2019
AbstractforInhibition of human glioblastoma cell invasion involves PION@E6 mediated autophagy process | Full Text | References | PDF (2.9 MB) | EPUB
  • 81 Views
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Article
Growth and differentiation factor 15 regulates PD-L1 expression in glioblastoma
Haiqin Peng, Zhanzhan Li, Jun Fu & Rongrong Zhou
Pages: 2653-2661
Published online: 02 Apr 2019
AbstractforGrowth and differentiation factor 15 regulates PD-L1 expression in glioblastoma | Full Text | References | PDF (534.5 KB) | EPUB
  • 107 Views
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Review

Review Article
Carfilzomib for relapsed and refractory multiple myeloma
K Groen, NWCJ van de Donk, CAM Stege, S Zweegman & IS Nijhof
Pages: 2663-2675
Published online: 02 Apr 2019
AbstractforCarfilzomib for relapsed and refractory multiple myeloma | Full Text | References | PDF (524 KB) | EPUB
  • 141 Views
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Original Research

Article
Differential effects of adjuvant EGFR tyrosine kinase inhibitors in patients with different stages of non-small-cell lung cancer after radical resection: an updated meta-analysis
Di Lu, Zhizhi Wang, Xiguang Liu, Siyang Feng, Xiaoying Dong, Xiaoshun Shi, He Wang, Hua Wu, Gang Xiong, Haofei Wang & Kaican Cai
Pages: 2677-2690
Published online: 02 Apr 2019
AbstractforDifferential effects of adjuvant EGFR tyrosine kinase inhibitors in patients with different stages of non-small-cell lung cancer after radical resection: an updated meta-analysis | Full Text | References | PDF (1.1 MB) | EPUB
  • 59 Views
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Article
Development and external validation of prognostic nomograms in hepatocellular carcinoma patients: a population based study
Zhiyu Xiao, Yongcong Yan, Qianlei Zhou, Haohan Liu, Pinbo Huang, Qiming Zhou, Changliang Lai, Jianlong Zhang, Jie Wang & Kai Mao
Pages: 2691-2708
Published online: 10 Apr 2019
AbstractforDevelopment and external validation of prognostic nomograms in hepatocellular carcinoma patients: a population based study | Full Text | References | PDF (1.2 MB) | EPUB
  • 63 Views
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Article
Self-expanding metallic stent as a bridge to surgery versus emergency surgery for acute obstructive colorectal cancer: a retrospective study
Yuliuming Wang, Hanqing Hu, Meng Wang, Xiao Han, Qian Zhang, Lei Yu, Yinggang Chen & Guiyu Wang
Pages: 2709-2718
Published online: 05 Apr 2019
AbstractforSelf-expanding metallic stent as a bridge to surgery versus emergency surgery for acute obstructive colorectal cancer: a retrospective study | Full Text | References | PDF (369.4 KB) | EPUB
  • 82 Views
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Article
Correlations of health-related quality of life with serum inflammatory indicators IL-8 and mIBI in patients with hepatocellular carcinoma
Leung Li, Stephen L Chan, Frankie Mo, Edwin P Hui, Jane Koh, Allen K C Chan, Nelson L S Tang, Kit F Lee, Paul B S Lai, Simon C H Yu & Winnie Yeo
Pages: 2719-2727
Published online: 04 Apr 2019
AbstractforCorrelations of health-related quality of life with serum inflammatory indicators IL-8 and mIBI in patients with hepatocellular carcinoma | Full Text | References | PDF (885.8 KB) | EPUB
  • 64 Views
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Review

Review Article
The role of long non-coding RNA GAS5 in cancers
Jiali Ji, Xiaolan Dai, Sai-Ching Jim Yeung & Xuexin He
Pages: 2729-2737
Published online: 08 Apr 2019
AbstractforThe role of long non-coding RNA GAS5 in cancers | Full Text | References | PDF (344 KB) | EPUB
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Original Research

Article
miR-101 regulates cell proliferation and apoptosis by targeting KDM1A in diffuse large B cell lymphoma
Yiqun Huang, Yong Zou, Luhui Lin, Xudong Ma & Ruiji Zheng
Pages: 2739-2746
Published online: 05 Apr 2019
AbstractformiR-101 regulates cell proliferation and apoptosis by targeting KDM1A in diffuse large B cell lymphoma | Full Text | References | PDF (2.1 MB) | EPUB
  • 62 Views
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Review

Review Article
Chromogranin A is a predictor of prognosis in patients with prostate cancer: a systematic review and meta-analysis
Zhenlang Guo, Yuliang Wang, Songtao Xiang, Shusheng Wang & Franky Leung Chan
Pages: 2747-2758
Published online: 05 Apr 2019
AbstractforChromogranin A is a predictor of prognosis in patients with prostate cancer: a systematic review and meta-analysis | Full Text | References | PDF (544.2 KB) | EPUB
  • 75 Views
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Article
Incidence, risk factors, and prognosis in patients with primary hepatocellular carcinoma and lung metastasis: a population-based study
Chao Wu, Xudong Ren & Quanbao Zhang
Pages: 2759-2768
Published online: 08 Apr 2019
AbstractforIncidence, risk factors, and prognosis in patients with primary hepatocellular carcinoma and lung metastasis: a population-based study | Full Text | References | PDF (965.5 KB) | EPUB
  • 182 Views
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Article
RETRACTED ARTICLE: microRNA-877 inhibits malignant progression of colorectal cancer by directly targeting MTDH and regulating the PTEN/Akt pathway
Lunqiang Zhang, Chenglong Li, Lijun Cao, Hui Li, Haiding Zou, Hongqin Li & Haiping Pei
Pages: 2769-2781
Published online: 08 Apr 2019
AbstractforRETRACTED ARTICLE: microRNA-877 inhibits malignant progression of colorectal cancer by directly targeting MTDH and regulating the PTEN/Akt pathway | PDF (1 MB)
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Article
Upregulation of FOXP4 in breast cancer promotes migration and invasion through facilitating EMT
Tao Ma & Jin Zhang
Pages: 2783-2793
Published online: 08 Apr 2019
AbstractforUpregulation of FOXP4 in breast cancer promotes migration and invasion through facilitating EMT | Full Text | References | PDF (4.9 MB) | EPUB
  • 104 Views
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Article
High miR-454-3p expression predicts poor prognosis in hepatocellular carcinoma
Yanqing Li, Yan Jiao, Zhuo Fu, Zhangping Luo, Jing Su & Yang Li
Pages: 2795-2802
Published online: 08 Apr 2019
AbstractforHigh miR-454-3p expression predicts poor prognosis in hepatocellular carcinoma | Full Text | References | PDF (415.7 KB) | EPUB
  • 65 Views
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Article
Wnt5a induces ROR1 and ROR2 to activate RhoA in esophageal squamous cell carcinoma cells
Xuping Wu, Ting Yan, Leiyu Hao & Yichao Zhu
Pages: 2803-2815
Published online: 10 Apr 2019
AbstractforWnt5a induces ROR1 and ROR2 to activate RhoA in esophageal squamous cell carcinoma cells | Full Text | References | PDF (1.1 MB) | EPUB
  • 74 Views
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Article
Dynamic impact of inflammation-based indices in colorectal cancer patients receiving FOLFOX-based chemotherapy
Yong Tao, Danping Yuan, Hongshuang Pang, Hongbiao Wu, Dongfang Liu, Ningning Jin, Ningning Wu, Jianming Qiu & Yuepeng Cao
Pages: 2817-2829
Published online: 10 Apr 2019
AbstractforDynamic impact of inflammation-based indices in colorectal cancer patients receiving FOLFOX-based chemotherapy | Full Text | References | PDF (501.5 KB) | EPUB
  • 105 Views
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Article
Suppressing growth and invasion of human hepatocellular carcinoma cells by celecoxib through inhibition of cyclooxygenase-2
Yang Tai, Lin-Hao Zhang, Jin-Hang Gao, Chong Zhao, Huan Tong, Cheng Ye, Zhi-Yin Huang, Rui Liu & Cheng-Wei Tang
Pages: 2831-2848
Published online: 09 Apr 2019
AbstractforSuppressing growth and invasion of human hepatocellular carcinoma cells by celecoxib through inhibition of cyclooxygenase-2 | Full Text | References | PDF (1.2 MB) | EPUB
  • 104 Views
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Article
Diabetes mellitus predicts inferior survival in diffuse large B-cell lymphoma: a propensity score-matched analysis
Rui Gao, Jin-Hua Liang, Tian-Shuo Man, Li Wang, Hua-Yuan Zhu, Wei Wu, Lei Fan, Jian-Yong Li, Tao Yang & Wei Xu
Pages: 2849-2870
Published online: 09 Apr 2019
AbstractforDiabetes mellitus predicts inferior survival in diffuse large B-cell lymphoma: a propensity score-matched analysis | Full Text | References | PDF (656.5 KB) | EPUB
  • 95 Views
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Article
LncRNA LOC105372579 promotes proliferation and epithelial-mesenchymal transition in hepatocellular carcinoma via activating miR-4316/FOXP4 signaling
Changyong E, Jinghui Yang, Hang Li & Chunsheng Li
Pages: 2871-2879
Published online: 11 Apr 2019
AbstractforLncRNA LOC105372579 promotes proliferation and epithelial-mesenchymal transition in hepatocellular carcinoma via activating miR-4316/FOXP4 signaling | Full Text | References | PDF (701.5 KB) | EPUB
  • 61 Views
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Article
Apolipoprotein A1 and B as risk factors for development of intraocular metastasis in patients with breast cancer
Jia-Xiang Liu, Qing Yuan, You-Lan Min, Ying He, Qian-Hui Xu, Biao Li, Wen-Qing Shi, Qi Lin, Qing-Hai Li, Pei-Wen Zhu & Yi Shao
Pages: 2881-2888
Published online: 09 Apr 2019
AbstractforApolipoprotein A1 and B as risk factors for development of intraocular metastasis in patients with breast cancer | Full Text | References | PDF (399.4 KB) | EPUB
  • 111 Views
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Article
Peri-tumor fibroblasts promote tumorigenesis and metastasis of hepatocellular carcinoma via Interleukin6/STAT3 signaling pathway
Zhenxiong Zhao, Si Xiong, Ronghua Wang, Yawen Li, Xiju Wang, Yun Wang, Shuya Bai, Wei Chen, Yuchong Zhao & Bin Cheng
Pages: 2889-2901
Published online: 10 Apr 2019
AbstractforPeri-tumor fibroblasts promote tumorigenesis and metastasis of hepatocellular carcinoma via Interleukin6/STAT3 signaling pathway | Full Text | References | PDF (1.1 MB) | EPUB
  • 70 Views
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Article
A quantified risk-scoring system including the visceral fat area for peritoneal metastasis of gastric cancer
Xiaodong Chen, Weisheng Chen, Yunshi Huang, Jingxuan Xu, Yunpeng Zeng, Mingming Shi, Libin Xu, Weiteng Zhang, Guanbao Zhu, Chenchen Mao & Xian Shen
Pages: 2903-2913
Published online: 10 Apr 2019
AbstractforA quantified risk-scoring system including the visceral fat area for peritoneal metastasis of gastric cancer | Full Text | References | PDF (334.3 KB) | EPUB
  • 68 Views
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Article
Tumor location of the central and nipple portion is associated with impaired survival for women with breast cancer
Fei Ji, Wei-Kai Xiao, Ci-Qiu Yang, Mei Yang, Liu-Lu Zhang, Hong-Fei Gao, Yu-Feng Lin, Teng Zhu, Min-Yi Cheng, Wei-Ping Li, Wei-Jun Pan, Xiao-Sheng Zhuang & Kun Wang
Pages: 2915-2925
Published online: 09 Apr 2019
AbstractforTumor location of the central and nipple portion is associated with impaired survival for women with breast cancer | Full Text | References | PDF (821.7 KB) | EPUB
  • 92 Views
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Article
Overexpressed pepsinogen C is associated with poor prognosis in human hepatocellular carcinoma: a tissue microarray study
Hong Chen, Hai-Rong Zhu, Xiang-Nan Yu, Xuan Shi, Enkhnaran Bilegsaikhan, Hong-Ying Guo, Ren-Zheng Huang, Tao-Tao Liu, Xi-Zhong Shen & Ji-Min Zhu
Pages: 2927-2934
Published online: 10 Apr 2019
AbstractforOverexpressed pepsinogen C is associated with poor prognosis in human hepatocellular carcinoma: a tissue microarray study | Full Text | References | PDF (464 KB) | EPUB
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Article
The serum proteomics tracking of hepatocellular carcinoma early recurrence following radical resection
Hongzhi Liu, Hui Chen, Xiaomo Wu, Ying Sun, Yingchao Wang, Yongyi Zeng, Geng Chen, Xiaolong Liu, Xiaohua Xing, Bixing Zhao & Jingfeng Liu
Pages: 2935-2946
Published online: 10 Apr 2019
AbstractforThe serum proteomics tracking of hepatocellular carcinoma early recurrence following radical resection | Full Text | References | PDF (695.1 KB) | EPUB
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Case Series

Skin graft using MatriDerm® for plantar defects after excision of skin cancer
Sang-Woo Kang, Ji-Kang Park, Hyun-Chul Shon, Eui-Sung Choi, Dong-Soo Kim & Kyoung-Tae Min
Pages: 2947-2950
Published online: 10 Apr 2019
AbstractforSkin graft using MatriDerm® for plantar defects after excision of skin cancer | Full Text | References | PDF (364 KB) | EPUB
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Original Research

Article
Meta-analysis of comparing part-solid and pure-solid tumors in patients with clinical stage IA non-small-cell lung cancer in the eighth edition TNM classification
Tian Jiang, Ming Li, Miao Lin, Mengnan Zhao, Cheng Zhan & Mingxiang Feng
Pages: 2951-2961
Published online: 10 Apr 2019
AbstractforMeta-analysis of comparing part-solid and pure-solid tumors in patients with clinical stage IA non-small-cell lung cancer in the eighth edition TNM classification | Full Text | References | PDF (850.3 KB) | EPUB
  • 71 Views
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Article
MicroRNA-34a suppresses aggressiveness of hepatocellular carcinoma by modulating E2F1, E2F3, and Caspase-3
Rui Han, Xinyi Chen, Ya Li, Shunjia Zhang, Ruibai Li & Lingeng Lu
Pages: 2963-2976
Published online: 10 Apr 2019
AbstractforMicroRNA-34a suppresses aggressiveness of hepatocellular carcinoma by modulating E2F1, E2F3, and Caspase-3 | Full Text | References | PDF (886.7 KB) | EPUB
  • 82 Views
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Article
Chrysin inhibits sphere formation in SMMC-7721 cells via modulation of SHP-1/STAT3 signaling pathway
Yanqin Zhang, Feng Chen, Xinghua Xiao, Weinan Pan, Qing Yuan & Jianguo Cao
Pages: 2977-2985
Published online: 10 Apr 2019
AbstractforChrysin inhibits sphere formation in SMMC-7721 cells via modulation of SHP-1/STAT3 signaling pathway | Full Text | References | PDF (648.4 KB) | EPUB
  • 52 Views
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Article
High CD3D/CD4 ratio predicts better survival in muscle-invasive bladder cancer
Ming-Jun Shi, Xiang-Yu Meng, Qiu-Ji Wu & Xiong-Hui Zhou
Pages: 2987-2995
Published online: 12 Apr 2019
AbstractforHigh CD3D/CD4 ratio predicts better survival in muscle-invasive bladder cancer | Full Text | References | PDF (622.7 KB) | EPUB
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Article
BCL11A enhances stemness and promotes progression by activating Wnt/β-catenin signaling in breast cancer
Lewei Zhu, Ruilin Pan, Dan Zhou, Guolin Ye & Weige Tan
Pages: 2997-3007
Published online: 11 Apr 2019
AbstractforBCL11A enhances stemness and promotes progression by activating Wnt/β-catenin signaling in breast cancer | Full Text | References | PDF (799.5 KB) | EPUB
  • 102 Views
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Article
Docetaxel, oxaliplatin, leucovorin, and 5-fluorouracil (FLOT) as preoperative and postoperative chemotherapy compared with surgery followed by chemotherapy for patients with locally advanced gastric cancer: a propensity score-based analysis
Keshen Wang, Yanxian Ren, Zhijian Ma, Fan Li, Xiaocheng Cheng, Jingying Xiao, Shuze Zhang, Zeyuan Yu, Hanteng Yang, Huinian Zhou, Yuming Li, Hongbin Liu & Zuo-Yi Jiao
Pages: 3009-3020
Published online: 10 Apr 2019
AbstractforDocetaxel, oxaliplatin, leucovorin, and 5-fluorouracil (FLOT) as preoperative and postoperative chemotherapy compared with surgery followed by chemotherapy for patients with locally advanced gastric cancer: a propensity score-based analysis | Full Text | References | PDF (367.9 KB) | EPUB
  • 182 Views
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Article
RRBP1 is highly expressed in prostate cancer and correlates with prognosis
Tieqiu Li, Qianqian Wang, Xiuqin Hong, Huahua Li, Ke Yang, Jiahui Li & Bin Lei
Pages: 3021-3027
Published online: 23 Apr 2019
AbstractforRRBP1 is highly expressed in prostate cancer and correlates with prognosis | Full Text | References | PDF (1.2 MB) | EPUB
  • 82 Views
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Article
Prognostic significance of combined pretreatment body mass index (BMI) and BMI loss in patients with esophageal cancer
Wen-Shen Gu, Wei-Zhen Fang, Chun-Yue Liu, Kun-Yi Pan, Rui Ding, Xiao-Hui Li & Chao-Hui Duan
Pages: 3029-3041
Published online: 10 Apr 2019
AbstractforPrognostic significance of combined pretreatment body mass index (BMI) and BMI loss in patients with esophageal cancer | Full Text | References | PDF (493 KB) | EPUB
  • 91 Views
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Article
Mortality trends of bladder cancer in China from 1991 to 2015: an age-period-cohort analysis
Yongli Yang, Zhiwei Cheng, Xiaocan Jia, Nian Shi, Zhenhua Xia, Weiping Zhang & Xuezhong Shi
Pages: 3043-3051
Published online: 10 Apr 2019
AbstractforMortality trends of bladder cancer in China from 1991 to 2015: an age-period-cohort analysis | Full Text | References | PDF (1.2 MB) | EPUB
  • 84 Views
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Article
High expression of dedicator of cytokinesis 1 adversely influences the prognosis of acute myeloid leukemia patients undergoing allogeneic hematopoietic stem cell transplantation
Gaoqi Zhang, Jilei Zhang, Xinrui Yang, Xinpei Zhang, Siyuan Yang, Jing Wang, Kai Hu, Jinlong Shi, Xiaoyan Ke & Lin Fu
Pages: 3053-3060
Published online: 11 Apr 2019
AbstractforHigh expression of dedicator of cytokinesis 1 adversely influences the prognosis of acute myeloid leukemia patients undergoing allogeneic hematopoietic stem cell transplantation | Full Text | References | PDF (299 KB) | EPUB
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Review

Review Article
Efficacy and safety of olaparib maintenance therapy in platinum-sensitive ovarian cancer patients with BRCA mutations: a meta-analysis on randomized controlled trials
Jiao Ma, Hongyong Deng, Jiajia Li, Shaopu Hu, Yanping Yang, Sheng Liu & Xianghui Han
Pages: 3061-3078
Published online: 16 Apr 2019
AbstractforEfficacy and safety of olaparib maintenance therapy in platinum-sensitive ovarian cancer patients with BRCA mutations: a meta-analysis on randomized controlled trials | Full Text | References | PDF (963.3 KB) | EPUB
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Original Research

Article
Early detection of prostate cancer using prostate-specific antigen testing: an empirical evaluation among general practitioners and urologists
Sanny Kappen, Verena Jürgens, Michael H Freitag & Alexander Winter
Pages: 3079-3097
Published online: 16 Apr 2019
AbstractforEarly detection of prostate cancer using prostate-specific antigen testing: an empirical evaluation among general practitioners and urologists | Full Text | References | PDF (432.9 KB) | EPUB
  • 118 Views
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Article
miR-526b-3p serves as a prognostic factor and regulates the proliferation, invasion, and migration of glioma through targeting WEE1
Ming Wu, Xuejun Li, Qing Liu, Yuanyang Xie, Jian Yuan & Siyi Wanggou
Pages: 3099-3110
Published online: 11 Apr 2019
AbstractformiR-526b-3p serves as a prognostic factor and regulates the proliferation, invasion, and migration of glioma through targeting WEE1 | Full Text | References | PDF (740.2 KB) | EPUB
  • 58 Views
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Article
RETRACTED ARTICLE: MicroRNA-665 inhibits the oncogenicity of retinoblastoma by directly targeting high-mobility group box 1 and inactivating the Wnt/β-catenin pathway
Shuai Wang, Shanshan Du, Yong Lv, Fengyan Zhang & Wenzhan Wang
Pages: 3111-3123
Published online: 11 Apr 2019
AbstractforRETRACTED ARTICLE: MicroRNA-665 inhibits the oncogenicity of retinoblastoma by directly targeting high-mobility group box 1 and inactivating the Wnt/β-catenin pathway | PDF (1.1 MB)
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Review

Review Article
Apparent diffusion coefficient in extraprostatic extension of prostate cancer: a systematic review and diagnostic meta-analysis
Koudi Bai, Yuan Sun, Wei Li & Lanlan Zhang
Pages: 3125-3137
Published online: 11 Apr 2019
AbstractforApparent diffusion coefficient in extraprostatic extension of prostate cancer: a systematic review and diagnostic meta-analysis | Full Text | References | PDF (463 KB) | EPUB
  • 77 Views
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Original Research

Article
Overexpression of the phospholipase A2 group V gene in glioma tumors is associated with poor patient prognosis
Changwu Wu, Jun Su, Xiangyu Wang, Junquan Wang, Kai Xiao, Yang Li, Qun Xiao, Min Ling, Yao Xiao, Chaoying Qin, Wenyong Long, Fengqi Zhang, Yimin Pan, Feng Xiang & Qing Liu
Pages: 3139-3152
Published online: 11 Apr 2019
AbstractforOverexpression of the phospholipase A2 group V gene in glioma tumors is associated with poor patient prognosis | Full Text | References | PDF (816.9 KB) | EPUB
  • 78 Views
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Article
Increased systemic immune-inflammation index independently predicts poor survival for hormone receptor-negative, HER2-positive breast cancer patients
Yi Sun, Wenqiang Li, Ai-Jie Li, Huichao Su, Jinbo Yue & Jinming Yu
Pages: 3153-3162
Published online: 11 Apr 2019
AbstractforIncreased systemic immune-inflammation index independently predicts poor survival for hormone receptor-negative, HER2-positive breast cancer patients | Full Text | References | PDF (369 KB) | EPUB
  • 114 Views
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Article
A simplified T classification based on the 8th edition of the UICC/AJCC staging system for nasopharyngeal carcinoma
Xing-Xi Pan, Li-Hua Tong, Yong-Fa Chen, Fei-Long Li, Wu-Bing Tang, Ya-Jie Liu & Wen Yang
Pages: 3163-3169
Published online: 11 Apr 2019
AbstractforA simplified T classification based on the 8th edition of the UICC/AJCC staging system for nasopharyngeal carcinoma | Full Text | References | PDF (225.5 KB) | EPUB
  • 76 Views
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Article
SLC5A1 promotes growth and proliferation of pancreatic carcinoma via glucose-dependent AMPK/mTOR signaling
Hui-Feng Gao, Lian-Yu Chen, Chien-Shan Cheng, Hao Chen, Zhi-Qiang Meng & Zhen Chen
Pages: 3171-3185
Published online: 12 Apr 2019
AbstractforSLC5A1 promotes growth and proliferation of pancreatic carcinoma via glucose-dependent AMPK/mTOR signaling | Full Text | References | PDF (964.3 KB) | EPUB
  • 129 Views
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Article
Assessment of the presence and anti-tumor potential of tumor-infiltrating lymphocytes in patients with acute myeloid leukemia
Liya Wei, Zhenkun Wang, Zhuo Zhang, Yinghua Li, Shengjin Fan, Yanqiu Zhao, Zhiyu Liu, Xiangmei Ye, Fan Zhang, Yingying Yu, Xiaolong Liu, Fenglin Cao & Jin Zhou
Pages: 3187-3196
Published online: 12 Apr 2019
AbstractforAssessment of the presence and anti-tumor potential of tumor-infiltrating lymphocytes in patients with acute myeloid leukemia | Full Text | References | PDF (480.9 KB) | EPUB
  • 82 Views
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Review

Review Article
Evaluating venetoclax and its potential in treatment-naïve acute myeloid leukemia
Tristan Knight, Holly Edwards, Jeffrey W Taub & Yubin Ge
Pages: 3197-3213
Published online: 23 Apr 2019
AbstractforEvaluating venetoclax and its potential in treatment-naïve acute myeloid leukemia | Full Text | References | PDF (303.4 KB) | EPUB
  • 162 Views
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Original Research

Article
Novel nomograms individually predict the survival of patients with soft tissue sarcomas after surgery
Shi-Long Zhang, Zhi-Ming Wang, Wen-Rong Wang, Xin Wang & Yu-Hong Zhou
Pages: 3215-3225
Published online: 15 Apr 2019
AbstractforNovel nomograms individually predict the survival of patients with soft tissue sarcomas after surgery | Full Text | References | PDF (496.2 KB) | EPUB
  • 70 Views
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Article
Isocitrate dehydrogenase 1 mutation is associated with reduced levels of inflammation in glioma patients
Raushan Auezova, Natalia Ivanova, Serik Akshulakov, Berik Zhetpisbaev, Aizhan Kozhakhmetova, Nurzhan Ryskeldiyev, Khalit Mustafin, Daniyar Teltayev & Lizette Auezova
Pages: 3227-3236
Published online: 15 Apr 2019
AbstractforIsocitrate dehydrogenase 1 mutation is associated with reduced levels of inflammation in glioma patients | Full Text | References | PDF (403.6 KB) | EPUB
  • 102 Views
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Article
RETRACTED ARTICLE: NPTX1 promotes metastasis via integrin/FAK signaling in gastric cancer
Hongfei Yan, Chunlei Zheng, Zhi Li, Bowen Bao, Bowen Yang, Kezuo Hou, Xiujuan Qu, Jiawen Xiao, Xiaofang Che & Yunpeng Liu
Pages: 3237-3251
Published online: 15 Apr 2019
AbstractforRETRACTED ARTICLE: NPTX1 promotes metastasis via integrin/FAK signaling in gastric cancer | PDF (7.6 MB)
  • 75 Views
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Article
CDKN3 promotes tumor progression and confers cisplatin resistance via RAD51 in esophageal cancer
Jiansong Wang, Wencheng Che, Weimin Wang, Gongzhang Su, Tianchang Zhen & Zhongmin Jiang
Pages: 3253-3264
Published online: 15 Apr 2019
AbstractforCDKN3 promotes tumor progression and confers cisplatin resistance via RAD51 in esophageal cancer | Full Text | References | PDF (858.3 KB) | EPUB
  • 93 Views
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Article
Prognostic values of preoperative platelet-to-lymphocyte ratio, albumin and hemoglobin in patients with non-metastatic colon cancer
Zhigui Li, Zhaofen Xu, Yuqian Huang, Rui Zhao, Yaping Cui, Yong Zhou & Xiaoting Wu
Pages: 3265-3274
Published online: 16 Apr 2019
AbstractforPrognostic values of preoperative platelet-to-lymphocyte ratio, albumin and hemoglobin in patients with non-metastatic colon cancer | Full Text | References | PDF (2 MB) | EPUB
  • 102 Views
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Article
Knockdown of CHPF suppresses cell progression of non-small-cell lung cancer
Xiao-Ming Hou, Zulqarnain Baloch, Zhan-Hong Zheng, Wen-Hui Zhang, Ying Feng, Duan-Duan Li, Xin-An Wu & Shi-Hua Yang
Pages: 3275-3283
Published online: 24 Apr 2019
AbstractforKnockdown of CHPF suppresses cell progression of non-small-cell lung cancer | Full Text | References | PDF (2.2 MB) | EPUB
  • 72 Views
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Article
Oncolytic viro-chemotherapy exhibits antitumor effect in laryngeal squamous cell carcinoma cells and mouse xenografts
Yigang Wang, Binrong Wang, Junnan Liang, Caixia Cui, Chang Ying, Fang Huang, Buyun Ma, Xiumei Zhou & Liang Chu
Pages: 3285-3294
Published online: 15 Apr 2019
AbstractforOncolytic viro-chemotherapy exhibits antitumor effect in laryngeal squamous cell carcinoma cells and mouse xenografts | Full Text | References | PDF (594.2 KB) | EPUB
  • 65 Views
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Review

Review Article
The beneficial effects of metformin on cancer prevention and therapy: a comprehensive review of recent advances
Pouya Saraei, Ilia Asadi, Muhammad Azam Kakar & Nasroallah Moradi-Kor
Pages: 3295-3313
Published online: 17 Apr 2019
AbstractforThe beneficial effects of metformin on cancer prevention and therapy: a comprehensive review of recent advances | Full Text | References | PDF (1.2 MB) | EPUB
  • 572 Views
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Original Research

Article
Identification of a transcription factor-microRNA network in esophageal adenocarcinoma through bioinformatics analysis and validation through qRT-PCR
Di Chen, Tong Lu, Junying Tan, Kun Zhao, Yuli Li, Wenjie Zhao, Hao Li, Qiuyue Wang, Yuanyong Wang & Liangzhou Wei
Pages: 3315-3326
Published online: 18 Apr 2019
AbstractforIdentification of a transcription factor-microRNA network in esophageal adenocarcinoma through bioinformatics analysis and validation through qRT-PCR | Full Text | References | PDF (3 MB) | EPUB
  • 72 Views
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Article
The systemic inflammation response index predicts survival and recurrence in patients with resectable pancreatic ductal adenocarcinoma
Shuo Li, Huaxiang Xu, Wenquan Wang, Heli Gao, Hao Li, Shirong Zhang, Jinzhi Xu, Wuhu Zhang, Shuaishuai Xu, Tianjiao Li, Quanxing Ni, Xianjun Yu, Chuntao Wu & Liang Liu
Pages: 3327-3337
Published online: 17 Apr 2019
AbstractforThe systemic inflammation response index predicts survival and recurrence in patients with resectable pancreatic ductal adenocarcinoma | Full Text | References | PDF (536.7 KB) | EPUB
  • 97 Views
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Article
Association between quantitative parameters of CEUS and Sall4/Wnt/β-catenin signaling in patients with hepatocellular carcinoma
Jianjun Wang, Jiaxin Huang, Qianfeng Ma & Guanghui Liu
Pages: 3339-3347
Published online: 17 Apr 2019
AbstractforAssociation between quantitative parameters of CEUS and Sall4/Wnt/β-catenin signaling in patients with hepatocellular carcinoma | Full Text | References | PDF (625.4 KB) | EPUB
  • 61 Views
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Letter

Letter
Approaches to interpret the outcomes of a network meta-analysis on comparative efficacy of different targeted therapies plus fulvestrant for advanced breast cancer following progression on prior endocrine therapy
Rama Jayaraj, Chellan Kumarasamy, Shanthi Sabarimurugan & Suja Samiappan
Pages: 3349-3350
Published online: 18 Apr 2019
CitationforApproaches to interpret the outcomes of a network meta-analysis on comparative efficacy of different targeted therapies plus fulvestrant for advanced breast cancer following progression on prior endocrine therapy | Full Text | References | PDF (171.9 KB) | EPUB
  • 55 Views
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Original Research

Article
Tumor-educated platelet miR-34c-3p and miR-18a-5p as potential liquid biopsy biomarkers for nasopharyngeal carcinoma diagnosis
Hui Wang, Xiuqi Wei, Bian Wu, Jingyu Su, Wenbin Tan & Kunyu Yang
Pages: 3351-3360
Published online: 17 Apr 2019
AbstractforTumor-educated platelet miR-34c-3p and miR-18a-5p as potential liquid biopsy biomarkers for nasopharyngeal carcinoma diagnosis | Full Text | References | PDF (1.7 MB) | EPUB
  • 100 Views
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Article
Primary tumor regression patterns in esophageal squamous cell cancer treated with definitive chemoradiotherapy and implications for surveillance schemes
Mingqiu Chen, Pingping Liu, Yuangui Chen, Zhiwei Chen, Minmin Shen, Xiaohong Liu, Xiqing Li, Yu Lin, Rongqiang Yang, Wei Ni, Xin Zhou, Lurong Zhang, Ye Tian & Junqiang Chen
Pages: 3361-3369
Published online: 17 Apr 2019
AbstractforPrimary tumor regression patterns in esophageal squamous cell cancer treated with definitive chemoradiotherapy and implications for surveillance schemes | Full Text | References | PDF (530.9 KB) | EPUB
  • 70 Views
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Article
A high absolute lymphocyte count predicts a poor prognosis in HER-2- positive breast cancer patients treated with trastuzumab
Jin Hong, Xiaosong Chen, Weiqi Gao, Siji Zhu, Jiayi Wu, Ou Huang, Jianrong He, Li Zhu, Weiguo Chen, Yafen Li, Xiaochun Fei, Lin Lin & Kunwei Shen
Pages: 3371-3379
Published online: 18 Apr 2019
AbstractforA high absolute lymphocyte count predicts a poor prognosis in HER-2- positive breast cancer patients treated with trastuzumab | Full Text | References | PDF (525.2 KB) | EPUB
  • 59 Views
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Article
Prognostic significance of the ratio of fibrinogen and albumin in human malignancies: a meta-analysis
Yi Zhang & Guoliang Xiao
Pages: 3381-3393
Published online: 23 Apr 2019
AbstractforPrognostic significance of the ratio of fibrinogen and albumin in human malignancies: a meta-analysis | Full Text | References | PDF (1.4 MB) | EPUB
  • 107 Views
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Article
FRMPD1 activates the Hippo pathway via interaction with WWC3 to suppress the proliferation and invasiveness of lung cancer cells
Xuezhu Rong, Qiang Han, Xuyong Lin, Joachim Kremerskothen & Enhua Wang
Pages: 3395-3410
Published online: 18 Apr 2019
AbstractforFRMPD1 activates the Hippo pathway via interaction with WWC3 to suppress the proliferation and invasiveness of lung cancer cells | Full Text | References | PDF (5.7 MB) | EPUB
  • 65 Views
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Review

Review Article
The crucial role of primary care providers in the long-term follow-up of adult survivors of childhood cancer
Justin Jain, Bessi Qorri & Myron R Szewczuk
Pages: 3411-3418
Published online: 23 Apr 2019
AbstractforThe crucial role of primary care providers in the long-term follow-up of adult survivors of childhood cancer | Full Text | References | PDF (838.7 KB) | EPUB
  • 130 Views
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Original Research

Article
Statins may have double-edged effects in patients with lung adenocarcinoma after lung resection
Shigeto Nishikawa, Toshi Menju, Koji Takahashi, Ryo Miyata, Toyofumi Fengshi Chen-Yoshikawa, Makoto Sonobe, Akihiko Yoshizawa, Hisataka Sabe, Tosiya Sato & Hiroshi Date
Pages: 3419-3432
Published online: 18 Apr 2019
AbstractforStatins may have double-edged effects in patients with lung adenocarcinoma after lung resection | Full Text | References | PDF (3.4 MB) | EPUB
  • 125 Views
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Article
Upfront whole brain radiotherapy for multiple brain metastases in patients with EGFR-mutant lung adenocarcinoma
Changhui Li, Jindong Guo, Lei Zhao, Fang Hu, Wei Nie, Huimin Wang, Xiaoxuan Zheng, Yinchen Shen, Ping Gu, Yujun Zhang & Xueyan Zhang
Pages: 3433-3443
Published online: 23 Apr 2019
AbstractforUpfront whole brain radiotherapy for multiple brain metastases in patients with EGFR-mutant lung adenocarcinoma | Full Text | References | PDF (1.5 MB) | EPUB
  • 98 Views
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Article
Assessment of potential predictive value of peripheral blood inflammatory indexes in 26 cases with soft tissue sarcoma treated by pazopanib: a retrospective study
Cem Mirili, Semra Paydaş, Isa B Guney, Ali Ogul, Serkan Gokcay, Mahmut Buyuksimsek, Abdullah E Yetisir, Bilgin Karaalioglu, Mert Tohumcuoglu & Gulsah Seydaoglu
Pages: 3445-3453
Published online: 23 Apr 2019
AbstractforAssessment of potential predictive value of peripheral blood inflammatory indexes in 26 cases with soft tissue sarcoma treated by pazopanib: a retrospective study | Full Text | References | PDF (2.4 MB) | EPUB
  • 88 Views
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Article
MicroRNA‑181c suppresses growth and metastasis of hepatocellular carcinoma by modulating NCAPG
Jiyuan Ai, Chengwu Gong, Junjun Wu, Jun Gao, Weiwei Liu, Wenjun Liao & Linquan Wu
Pages: 3455-3467
Published online: 23 Apr 2019
AbstractforMicroRNA‑181c suppresses growth and metastasis of hepatocellular carcinoma by modulating NCAPG | Full Text | References | PDF (5.1 MB) | EPUB
  • 81 Views
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Antitumor effects of Endostar(rh-endostatin) combined with gemcitabine in different administration sequences to treat Lewis lung carcinoma
Yuan Li, Pan Huang, Hongju Peng, Hongcheng Yue, Min Wu, Shanshan Liu, Rongsheng Qin, Juan Fan & Yunwei Han
Pages: 3469-3479
Published online: 23 Apr 2019
AbstractforAntitumor effects of Endostar(rh-endostatin) combined with gemcitabine in different administration sequences to treat Lewis lung carcinoma | Full Text | References | PDF (3.1 MB) | EPUB
  • 84 Views
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Review

Review Article
The role of visfatin in cancer proliferation, angiogenesis, metastasis, drug resistance and clinical prognosis
Tsung-Chieh Lin
Pages: 3481-3491
Published online: 23 Apr 2019
AbstractforThe role of visfatin in cancer proliferation, angiogenesis, metastasis, drug resistance and clinical prognosis | Full Text | References | PDF (1.4 MB) | EPUB
  • 189 Views
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Original Research

Article
High expression of SMARCE1 predicts poor prognosis and promotes cell growth and metastasis in gastric cancer
Hao Liu, Yan-Rong Zhao, Bo Chen, Zheng Ge & Jiang-Sheng Huang
Pages: 3493-3509
Published online: 23 Apr 2019
AbstractforHigh expression of SMARCE1 predicts poor prognosis and promotes cell growth and metastasis in gastric cancer | Full Text | References | PDF (7.9 MB) | EPUB
  • 103 Views
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The predictive value of high-density lipoprotein for ocular metastases in colorectal cancer patients
Pei-Wen Zhu, Ying-Xin Gong, You-Lan Min, Qi Lin, Biao Li, Wen-Qing Shi, Qing Yuan, Lei Ye & Yi Shao
Pages: 3511-3519
Published online: 29 Apr 2019
AbstractforThe predictive value of high-density lipoprotein for ocular metastases in colorectal cancer patients | Full Text | References | PDF (1.1 MB) | EPUB
  • 55 Views
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Article
MicroRNA-17 promotes cell proliferation and migration in human colorectal cancer by downregulating SIK1
Chengzhi Huang, Jianhua Liu, Lishu Xu, Weixian Hu, Junjiang Wang, Muqing Wang & Xueqing Yao
Pages: 3521-3534
Published online: 24 Apr 2019
AbstractforMicroRNA-17 promotes cell proliferation and migration in human colorectal cancer by downregulating SIK1 | Full Text | References | PDF (3.4 MB) | EPUB
  • 84 Views
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Article
Nomograms for estimating survival in patients with papillary thyroid cancer after surgery
Gang Liu, Qin Liu & Sheng-Rong Sun
Pages: 3535-3544
Published online: 24 Apr 2019
AbstractforNomograms for estimating survival in patients with papillary thyroid cancer after surgery | Full Text | References | PDF (1.1 MB) | EPUB
  • 66 Views
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Article
The prognostic value of serum albumin–globulin ratio in early-stage non-small cell lung cancer: a retrospective study
Yan Wang, Shuangjiang Li, Xu Hu, Yanwen Wang, Yanming Wu, Pengfei Li & Guowei Che
Pages: 3545-3554
Published online: 24 Apr 2019
AbstractforThe prognostic value of serum albumin–globulin ratio in early-stage non-small cell lung cancer: a retrospective study | Full Text | References | PDF (1.2 MB) | EPUB
  • 92 Views
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Clinical Trial Report

Clinical efficacy of cisplatin, dexamethasone, gemcitabine and pegaspargase (DDGP) in the initial treatment of advanced stage (stage III–IV) extranodal NK/T-cell lymphoma, and its correlation with Epstein-Barr virus
Qian Zhao, Shanshan Fan, Yu Chang, Xiyang Liu, Wencai Li, Qianwen Ma, Yang Li, Yan Wang, Lei Zhang & Mingzhi Zhang
Pages: 3555-3564
Published online: 24 Apr 2019
AbstractforClinical efficacy of cisplatin, dexamethasone, gemcitabine and pegaspargase (DDGP) in the initial treatment of advanced stage (stage III–IV) extranodal NK/T-cell lymphoma, and its correlation with Epstein-Barr virus | Full Text | References | PDF (365.9 KB) | EPUB
  • 71 Views
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Original Research

Article
lncRNA BANCR suppresses cell viability and invasion and promotes apoptosis in non-small-cell lung cancer cells in vitro and in vivo
Liu Yang & Guiting Liu
Pages: 3565-3574
Published online: 26 Apr 2019
AbstractforlncRNA BANCR suppresses cell viability and invasion and promotes apoptosis in non-small-cell lung cancer cells in vitro and in vivo | Full Text | References | PDF (2.7 MB) | EPUB
  • 76 Views
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Article
Fibrin-thrombin sealant does not reduce lymphocele formation in patients with inguinofemoral lymphadenectomy for vulvar cancer
Flurina AM Saner, Andreas Schötzau, Gillian Mackay, Viola Heinzelmann-Schwarz & Céline Montavon Sartorius
Pages: 3575-3582
Published online: 30 Apr 2019
AbstractforFibrin-thrombin sealant does not reduce lymphocele formation in patients with inguinofemoral lymphadenectomy for vulvar cancer | Full Text | References | PDF (768.2 KB) | EPUB
  • 74 Views
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Article
The efficacy and safety of apatinib in metastatic alveolar soft part sarcoma: a case series of six patients in one institution
Yitian Wang, Li Min, Yong Zhou, Fan Tang, Yi Luo, Wenli Zhang, Hong Duan & Chongqi Tu
Pages: 3583-3591
Published online: 26 Apr 2019
AbstractforThe efficacy and safety of apatinib in metastatic alveolar soft part sarcoma: a case series of six patients in one institution | Full Text | References | PDF (6.6 MB) | EPUB
  • 71 Views
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Article
Downregulation of CD166 inhibits invasion, migration, and EMT in the radio-resistant human nasopharyngeal carcinoma cell line CNE-2R
Yongchu Sun, Huan Lin, Song Qu, Ling Li, Kaihua Chen, Binbin Yu, Guoxiang Lin, Fangzhu Wan & Xiaodong Zhu
Pages: 3593-3602
Published online: 26 Apr 2019
AbstractforDownregulation of CD166 inhibits invasion, migration, and EMT in the radio-resistant human nasopharyngeal carcinoma cell line CNE-2R | Full Text | References | PDF (3 MB) | EPUB
  • 63 Views
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Article
Impact of pelvic MRI in routine clinical practice on staging of IB1–IIA2 cervical cancer
Weifeng Zhang, Chunlin Chen, Ping Liu, Weili Li, Min Hao, Weidong Zhao, Anwei Lu & Yan Ni
Pages: 3603-3609
Published online: 26 Apr 2019
AbstractforImpact of pelvic MRI in routine clinical practice on staging of IB1–IIA2 cervical cancer | Full Text | References | PDF (222.5 KB) | EPUB
  • 88 Views
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Article
Prognostic significance of serum lactate dehydrogenase in patients with breast cancer: a meta-analysis
Dongbo Liu, Dingkun Wang, Cheng Wu, Linli Zhang, Qi Mei, Guangyuan Hu, Guoxian Long & Wei Sun
Pages: 3611-3619
Published online: 26 Apr 2019
AbstractforPrognostic significance of serum lactate dehydrogenase in patients with breast cancer: a meta-analysis | Full Text | References | PDF (1.4 MB) | EPUB
  • 121 Views
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Retraction

Retraction
Identification of potential key genes associated with ovarian clear cell carcinoma [Retraction]
Pages: 3621-3622
Published online: 26 Apr 2019
CitationforIdentification of potential key genes associated with ovarian clear cell carcinoma [Retraction] | Full Text | PDF (150.4 KB) | EPUB
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Original Research

Article
Nutritional and clinical outcomes of chemoradiotherapy for clinical T1N0M0 esophageal carcinoma
Katsuyuki Sakanaka, Kota Fujii, Yuichi Ishida, Shin’ichi Miyamoto, Takahiro Horimatsu, Manabu Muto & Takashi Mizowaki
Pages: 3623-3630
Published online: 26 Apr 2019
AbstractforNutritional and clinical outcomes of chemoradiotherapy for clinical T1N0M0 esophageal carcinoma | Full Text | References | PDF (817.2 KB) | EPUB
  • 64 Views
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Article
Immune inflammation indicators in anal cancer patients treated with concurrent chemoradiation: training and validation cohort with online calculator (ARC: Anal Cancer Response Classifier)
Andrea Casadei-Gardini, Francesco Montagnani, Chiara Casadei, Francesca Arcadipane, Kalliopi Andrikou, Deborah Aloi, Alessandra Anna Prete, Maria Giulia Zampino, Antonella Argentiero, Giuseppe Pugliese, Stefania Martini, Giuseppe Carlo Iorio, Mario Scartozzi, Massimiliano Mistrangelo, Lorenzo Fornaro, Paola Cassoni, Giorgia Marisi, Veronica Dell’Acqua, Paola Simona Ravenda, Sara Lonardi, Nicola Silvestris, Berardino De Bari, Umberto Ricardi, Stefano Cascinu & Pierfrancesco Franco
Pages: 3631-3642
Published online: 26 Apr 2019
AbstractforImmune inflammation indicators in anal cancer patients treated with concurrent chemoradiation: training and validation cohort with online calculator (ARC: Anal Cancer Response Classifier) | Full Text | References | PDF (911.1 KB) | EPUB
  • 72 Views
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Article
Human papillomavirus DNA in surgical smoke during cervical loop electrosurgical excision procedures and its impact on the surgeon
Qingfeng Zhou, Xiaoli Hu, Junhan Zhou, Menghuang Zhao, Xuejie Zhu & Xueqiong Zhu
Pages: 3643-3654
Published online: 29 Apr 2019
AbstractforHuman papillomavirus DNA in surgical smoke during cervical loop electrosurgical excision procedures and its impact on the surgeon | Full Text | References | PDF (514.6 KB) | EPUB
  • 187 Views
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Article
Multiphoton microscopy in the diagnostic assessment of pediatric solid tissue in comparison to conventional histopathology: results of the first international online interobserver trial
Jan Goedeke, Peter Schreiber, Larissa Seidmann, Geling Li, Jérôme Birkenstock, Frank Simon, Jochem König & Oliver J Muensterer
Pages: 3655-3667
Published online: 29 Apr 2019
AbstractforMultiphoton microscopy in the diagnostic assessment of pediatric solid tissue in comparison to conventional histopathology: results of the first international online interobserver trial | Full Text | References | PDF (1.6 MB) | EPUB
  • 78 Views
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Article
Synergistic interaction of gemcitabine and paclitaxel by modulating acetylation and polymerization of tubulin in non-small cell lung cancer cell lines
Wiwin Is Effendi, Tatsuya Nagano, Motoko Tachihara, Kanoko Umezawa, Tatsunori Kiriu, Ryota Dokuni, Masahiro Katsurada, Masatsugu Yamamoto, Kazuyuki Kobayashi & Yoshihiro Nishimura
Pages: 3669-3679
Published online: 29 Apr 2019
AbstractforSynergistic interaction of gemcitabine and paclitaxel by modulating acetylation and polymerization of tubulin in non-small cell lung cancer cell lines | Full Text | References | PDF (1.8 MB) | EPUB
  • 137 Views
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Article
Baseline platelet counts and derived inflammatory biomarkers: prognostic relevance in metastatic melanoma patients receiving Endostar plus dacarbazine and cisplatin
Lingge Yang, Yu Xu, Peng Luo, Shiqi Chen, Huiyan Zhu & Chunmeng Wang
Pages: 3681-3690
Published online: 29 Apr 2019
AbstractforBaseline platelet counts and derived inflammatory biomarkers: prognostic relevance in metastatic melanoma patients receiving Endostar plus dacarbazine and cisplatin | Full Text | References | PDF (987.7 KB) | EPUB
  • 64 Views
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Article
Apolipoprotein M could inhibit growth and metastasis of SMMC7721 cells via vitamin D receptor signaling
Miaomei Yu, Lili Pan, Chen Sang, Qinfeng Mu, Lu Zheng, Guanghua Luo & Ning Xu
Pages: 3691-3701
Published online: 30 Apr 2019
AbstractforApolipoprotein M could inhibit growth and metastasis of SMMC7721 cells via vitamin D receptor signaling | Full Text | References | PDF (3.2 MB) | EPUB
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Article
A serum piRNA signature as promising non-invasive diagnostic and prognostic biomarkers for colorectal cancer
Ailin Qu, Wenfei Wang, Yongmei Yang, Xin Zhang, Yuhuan Dong, Guixi Zheng, Qiuyan Wu, Mingjin Zou, Lutao Du, Yunshan Wang & Chuanxin Wang
Pages: 3703-3720
Published online: 29 Apr 2019
AbstractforA serum piRNA signature as promising non-invasive diagnostic and prognostic biomarkers for colorectal cancer | Full Text | References | PDF (3.4 MB) | EPUB
  • 148 Views
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Article
Mutation spectrum of germline cancer susceptibility genes among unselected Chinese colorectal cancer patients
Rui Gong, Yuan He, Xiao-Yun Liu, Hai-Yun Wang, Li-Yue Sun, Xin-Hua Yang, Bin Li, Xin-Kai Cao, Zu-Lu Ye, Ling-Heng Kong, Da-Dong Zhang, Yu-Hong Li, Rui-Hua Xu & Jian-Yong Shao
Pages: 3721-3739
Published online: 29 Apr 2019
AbstractforMutation spectrum of germline cancer susceptibility genes among unselected Chinese colorectal cancer patients | Full Text | References | PDF (3.2 MB) | EPUB
  • 152 Views
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Article
CLDN8 promotes colorectal cancer cell proliferation, migration, and invasion by activating MAPK/ERK signaling
Bo Cheng, Aimei Rong, Quanbo Zhou & Wenlu Li
Pages: 3741-3751
Published online: 30 Apr 2019
AbstractforCLDN8 promotes colorectal cancer cell proliferation, migration, and invasion by activating MAPK/ERK signaling | Full Text | References | PDF (8.4 MB) | EPUB
  • 104 Views
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Article
A new predictor is comparable to the updated nomogram in predicting the intermediate- and high-risk prostate cancer but outperforms nomogram in reducing the overtreatment for the low-risk Pca
Hui Wang, Sheng Tai, Li Zhang, Jun Zhou & Chaozhao Liang
Pages: 3753-3763
Published online: 30 Apr 2019
AbstractforA new predictor is comparable to the updated nomogram in predicting the intermediate- and high-risk prostate cancer but outperforms nomogram in reducing the overtreatment for the low-risk Pca | Full Text | References | PDF (1.5 MB) | EPUB
  • 60 Views
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Article
Functional analysis and clinical significance of the isocitrate dehydrogenase 2 gene in papillary thyroid carcinoma
Jun Zhang, Linfei Hu, Huijuan Wang, Jingtai Zhi, Xiukun Hou, Yu Wu, Xiangqian Zheng & Ming Gao
Pages: 3765-3777
Published online: 01 May 2019
AbstractforFunctional analysis and clinical significance of the isocitrate dehydrogenase 2 gene in papillary thyroid carcinoma | Full Text | References | PDF (3.1 MB) | EPUB
  • 92 Views
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Article
FOXM1 promotes the growth and metastasis of colorectal cancer via activation of β-catenin signaling pathway
Kankan Yang, Bing Jiang, Yecai Lu, Qingbing Shu, Pan Zhai, Qiaoming Zhi & Qixin Li
Pages: 3779-3790
Published online: 01 May 2019
AbstractforFOXM1 promotes the growth and metastasis of colorectal cancer via activation of β-catenin signaling pathway | Full Text | References | PDF (3.4 MB) | EPUB
  • 114 Views
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Article
Survival benefit of higher fraction dose delivered by three-dimensional conformal radiotherapy in hepatocellular carcinoma smaller than 10 cm in size
Fang Su, Kaihua Chen, Zhongguo Liang, Song Qu, Ling Li, Long Chen, Yunli Yang, Chunhua Wu, Xia Liang & Xiaodong Zhu
Pages: 3791-3799
Published online: 30 Apr 2019
AbstractforSurvival benefit of higher fraction dose delivered by three-dimensional conformal radiotherapy in hepatocellular carcinoma smaller than 10 cm in size | Full Text | References | PDF (779.1 KB) | EPUB
  • 59 Views
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Article
MicroRNA-145 inhibits growth of laryngeal squamous cell carcinoma by targeting the PI3K/Akt signaling pathway
Dong Ye, Chongchang Zhou, Hongxia Deng, Lexi Lin & Shuihong Zhou
Pages: 3801-3812
Published online: 30 Apr 2019
AbstractforMicroRNA-145 inhibits growth of laryngeal squamous cell carcinoma by targeting the PI3K/Akt signaling pathway | Full Text | References | PDF (2.5 MB) | EPUB
  • 76 Views
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Article
lncRNA CADM1-AS1 inhibits cell-cycle progression and invasion via PTEN/AKT/GSK-3β axis in hepatocellular carcinoma
Fan Wang, Xun Qi, Zixuan Li, Shiqi Jin, Yang Xie & Hongshan Zhong
Pages: 3813-3828
Published online: 30 Apr 2019
AbstractforlncRNA CADM1-AS1 inhibits cell-cycle progression and invasion via PTEN/AKT/GSK-3β axis in hepatocellular carcinoma | Full Text | References | PDF (4.2 MB) | EPUB
  • 152 Views
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Article
KDR inferred haplotype is associated with upper limb dysfunction in breast cancer survivors of mixed ancestry
Trevor S Mafu, Alison V September & Delva Shamley
Pages: 3829-3845
Published online: 01 May 2019
AbstractforKDR inferred haplotype is associated with upper limb dysfunction in breast cancer survivors of mixed ancestry | Full Text | References | PDF (334 KB) | EPUB
  • 65 Views
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Review

Review Article
Lenvatinib, a molecule with versatile application: from preclinical evidence to future development in anti-cancer treatment
Monica Capozzi, Chiara De Divitiis, Alessandro Ottaiano, Claudia von Arx, Stefania Scala, Fabiana Tatangelo, Paolo Delrio & Salvatore Tafuto
Pages: 3847-3860
Published online: 01 May 2019
AbstractforLenvatinib, a molecule with versatile application: from preclinical evidence to future development in anti-cancer treatment | Full Text | References | PDF (273.4 KB) | EPUB
  • 225 Views
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Original Research

Article
Functional variants of lncRNA LINC00673 and gastric cancer susceptibility: a case-control study in a Chinese population
Kexin Zhao, Rui Zhang, Tiantian Li & Zhifan Xiong
Pages: 3861-3868
Published online: 01 May 2019
AbstractforFunctional variants of lncRNA LINC00673 and gastric cancer susceptibility: a case-control study in a Chinese population | Full Text | References | PDF (415.9 KB) | EPUB
  • 70 Views
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Article
The influence of sex on the prognostic value of body mass index in non-metastasis renal cell carcinoma
Yangqin Zheng, Lianmin Bao, Jingfeng Chen, Yue Pan, Qinquan Wang, Lianguo Chen & Xiaomin Gao
Pages: 3869-3886
Published online: 01 May 2019
AbstractforThe influence of sex on the prognostic value of body mass index in non-metastasis renal cell carcinoma | Full Text | References | PDF (1.5 MB) | EPUB
  • 59 Views
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Article
Disulfiram inhibits epithelial–mesenchymal transition through TGFβ–ERK–Snail pathway independently of Smad4 to decrease oral squamous cell carcinoma metastasis
Wenhuan Bu, Zilin Wang, Lin Meng, Xing Li, Xinchen Liu, Yumeng Chen, Ying Xin, Baoquan Li & Hongchen Sun
Pages: 3887-3898
Published online: 01 May 2019
AbstractforDisulfiram inhibits epithelial–mesenchymal transition through TGFβ–ERK–Snail pathway independently of Smad4 to decrease oral squamous cell carcinoma metastasis | Full Text | References | PDF (5.4 MB) | EPUB
  • 87 Views
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Review

Review Article
Total pancreatectomy compared with pancreaticoduodenectomy: a systematic review and meta-analysis
Du-Jiang Yang, Jun-Jie Xiong, Xue-Ting Liu, Jiao Li, Kanagarathna Mudiyanselage Dhanushka Layanthi Siriwardena & Wei-Ming Hu
Pages: 3899-3908
Published online: 07 May 2019
AbstractforTotal pancreatectomy compared with pancreaticoduodenectomy: a systematic review and meta-analysis | Full Text | References | PDF (2.1 MB) | EPUB
  • 90 Views
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Original Research

Article
Relationship between Helicobacter pylori and expression of programmed death-1 and its ligand in gastric intraepithelial neoplasia and early-stage gastric cancer
Bo Shen, Aihua Qian, Wenji Lao, Weiguang Li, Xi Chen, Benyan Zhang, Huafeng Wang, Fei Yuan & Yunwei Sun
Pages: 3909-3919
Published online: 02 May 2019
AbstractforRelationship between Helicobacter pylori and expression of programmed death-1 and its ligand in gastric intraepithelial neoplasia and early-stage gastric cancer | Full Text | References | PDF (3.2 MB) | EPUB
  • 72 Views
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Article
Expression profiles and prognostic significance of RNA N6-methyladenosine-related genes in patients with hepatocellular carcinoma: evidence from independent datasets
Yu Zhou, Zi Yin, Baohua Hou, Min Yu, Ruiwan Chen, Haosheng Jin & Zhixiang Jian
Pages: 3921-3931
Published online: 01 May 2019
AbstractforExpression profiles and prognostic significance of RNA N6-methyladenosine-related genes in patients with hepatocellular carcinoma: evidence from independent datasets | Full Text | References | PDF (3.4 MB) | EPUB
  • 82 Views
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Article
T-lymphoid/myeloid mixed phenotype acute leukemia and early T-cell precursor lymphoblastic leukemia similarities with NOTCH1 mutation as a good prognostic factor
Elda Pereira Noronha, Luísa Vieira Codeço Marques, Francianne Gomes Andrade, Ingrid Sardou-Cezar, Filipe Vicente dos Santos-Bueno, Carolina Da Paz Zampier, Eugênia Terra-Granado & Maria S Pombo-de-Oliveira
Pages: 3933-3943
Published online: 02 May 2019
AbstractforT-lymphoid/myeloid mixed phenotype acute leukemia and early T-cell precursor lymphoblastic leukemia similarities with NOTCH1 mutation as a good prognostic factor | Full Text | References | PDF (1.8 MB) | EPUB
  • 104 Views
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Article
Small RNA sequencing reveals a novel tsRNA-26576 mediating tumorigenesis of breast cancer
Jun Zhou, Fang Wan, Yike Wang, Jinpei Long & Xuan Zhu
Pages: 3945-3956
Published online: 02 May 2019
AbstractforSmall RNA sequencing reveals a novel tsRNA-26576 mediating tumorigenesis of breast cancer | Full Text | References | PDF (2.6 MB) | EPUB
  • 140 Views
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Article
Incidence risk of PD-1/PD-L1 related diarrhea in non-small cell lung cancer (NSCLC) patients: a systematic review and meta-analysis
Caiqing Zhang, Shuisheng Zhang, Deguo Xu, Rujun Liu, Qingshan Zhu, Yi Zhao, Yantao Mao & Yuan Tian
Pages: 3957-3969
Published online: 02 May 2019
AbstractforIncidence risk of PD-1/PD-L1 related diarrhea in non-small cell lung cancer (NSCLC) patients: a systematic review and meta-analysis | Full Text | References | PDF (3.1 MB) | EPUB
  • 58 Views
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Corrigendum

Correction
LncRNA LOC105372579 promotes proliferation and epithelial-mesenchymal transition in hepatocellular carcinoma via activating miR-4316/FOXP4 signaling [Corrigendum]
Page: 3971
Published online: 02 May 2019
CitationforLncRNA LOC105372579 promotes proliferation and epithelial-mesenchymal transition in hepatocellular carcinoma via activating miR-4316/FOXP4 signaling [Corrigendum] | Full Text | PDF (147.3 KB) | EPUB
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Original Research

Article
High systemic immune–inflammation index represents an unfavorable prognosis of malignant pleural mesothelioma
Ming Ma, Nina Yu & Bing Wu
Pages: 3973-3979
Published online: 02 May 2019
AbstractforHigh systemic immune–inflammation index represents an unfavorable prognosis of malignant pleural mesothelioma | Full Text | References | PDF (569.1 KB) | EPUB
  • 79 Views
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Article
Development and validation of a nomogram to predict liver metastasis in patients with pancreatic ductal adenocarcinoma: a large cohort study
Chaobin He, Lixin Zhong, Yu Zhang, Zhiyuan Cai & Xiaojun Lin
Pages: 3981-3991
Published online: 02 May 2019
AbstractforDevelopment and validation of a nomogram to predict liver metastasis in patients with pancreatic ductal adenocarcinoma: a large cohort study | Full Text | References | PDF (1.4 MB) | EPUB
  • 66 Views
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Article
A real-world evidence of efficacy of palliative gastrectomy plus chemotherapy in metastatic gastric cancer patients
Lu-Ping Yang, Zi-Xian Wang, Ming-Ming He, Hao-Xiang Wu, Shu-Qiang Yuan, Wei Wang, Ying Jin, Chao Ren, Zhi-Qiang Wang, Feng-Hua Wang, Yu-Hong Li, Feng Wang & Rui-Hua Xu
Pages: 3993-4003
Published online: 02 May 2019
AbstractforA real-world evidence of efficacy of palliative gastrectomy plus chemotherapy in metastatic gastric cancer patients | Full Text | References | PDF (998.5 KB) | EPUB
  • 71 Views
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Review

Article
Weight control is vital for patients with early-stage endometrial cancer or complex atypical hyperplasia who have received progestin therapy to spare fertility: a systematic review and meta-analysis
Miaomiao Li, Tao Guo, Ran Cui, Ying Feng, Huimin Bai & Zhenyu Zhang
Pages: 4005-4021
Published online: 06 May 2019
AbstractforWeight control is vital for patients with early-stage endometrial cancer or complex atypical hyperplasia who have received progestin therapy to spare fertility: a systematic review and meta-analysis | Full Text | References | PDF (912.8 KB) | EPUB
  • 90 Views
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Original Research

Article
Exosomal miRNA-107 induces myeloid-derived suppressor cell expansion in gastric cancer
WeiHong Ren, XuRan Zhang, WenBo Li, Qian Feng, HuiJie Feng, Yan Tong, Hao Rong, Wei Wang, Dai Zhang, ZhenQiang Zhang, ShiChun Tu, XiaoYan Zhu & QinXian Zhang
Pages: 4023-4040
Published online: 06 May 2019
AbstractforExosomal miRNA-107 induces myeloid-derived suppressor cell expansion in gastric cancer | Full Text | References | PDF (5.9 MB) | EPUB
  • 161 Views
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Review

Review Article
Prognostic value of tumor-associated macrophages in pancreatic cancer: a meta-analysis
Min Yu, Renguo Guan, Weifeng Hong, Yu Zhou, Ye Lin, Haosheng Jin, Baohua Hou & Zhixiang Jian
Pages: 4041-4058
Published online: 03 May 2019
AbstractforPrognostic value of tumor-associated macrophages in pancreatic cancer: a meta-analysis | Full Text | References | PDF (4.5 MB) | EPUB
  • 153 Views
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Original Research

Article
Intake consumption of ginsenoside Rg3, profiling of selected cytokines, and development of rectal polyps
Jian Xie, Shicheng Luo, Hongying Mi, Yibin Du, Guohong Bao, Jing Zhou, Yumei Xi & Cichun Li
Pages: 4059-4064
Published online: 06 May 2019
AbstractforIntake consumption of ginsenoside Rg3, profiling of selected cytokines, and development of rectal polyps | Full Text | References | PDF (215.4 KB) | EPUB
  • 53 Views
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Article
Adjuvant trans-arterial chemoembolization after hepatectomy significantly improves the prognosis of low-risk patients with R0-stage hepatocellular carcinoma
Hui Xie, Shengtao Tian, Li Cui, Jieyu Yan, Yanhua Bai, Xiaohui Li, Maoqiang Wang, Fangfang Zhang & Feng Duan
Pages: 4065-4073
Published online: 03 May 2019
AbstractforAdjuvant trans-arterial chemoembolization after hepatectomy significantly improves the prognosis of low-risk patients with R0-stage hepatocellular carcinoma | Full Text | References | PDF (450.9 KB) | EPUB
  • 69 Views
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Article
Impact of high-mobility-group A2 overexpression on epithelial-mesenchymal transition in pancreatic cancer
Jian Gong, Yuxiang Wang, Buping Jiang, Bin Xu & Chuanzhen Hu
Pages: 4075-4084
Published online: 03 May 2019
AbstractforImpact of high-mobility-group A2 overexpression on epithelial-mesenchymal transition in pancreatic cancer | Full Text | References | PDF (2.1 MB) | EPUB
  • 66 Views
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Article
Whole exome sequencing of multiple meningiomas with varying histopathological presentation in one patient revealed distinctive somatic mutation burden and independent clonal origins
Han-Song Sheng, Fang Shen, Nu Zhang, Li-Sheng Yu, Xiang-Qi Lu, Zhe Zhang, Huang-Yi Fang, Ling-Li Zhou & Jian Lin
Pages: 4085-4095
Published online: 06 May 2019
AbstractforWhole exome sequencing of multiple meningiomas with varying histopathological presentation in one patient revealed distinctive somatic mutation burden and independent clonal origins | Full Text | References | PDF (4 MB) | EPUB
  • 79 Views
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Article
The utility of folate receptor-positive circulating tumor cell in cancer diagnosis in the elderly population
Na Li, Dingrong Zhong, Huang Chen, Tiequn Huang, Pihua Hou, Yinan Zhang, Fangling Chen, Xiaoping Wang & Hongchun Zhang
Pages: 4097-4107
Published online: 06 May 2019
AbstractforThe utility of folate receptor-positive circulating tumor cell in cancer diagnosis in the elderly population | Full Text | References | PDF (1 MB) | EPUB
  • 68 Views
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Article
The safety and serious adverse events of approved ALK inhibitors in malignancies: a meta-analysis
Helei Hou, Dantong Sun, Kewei Liu, Man Jiang, Dong Liu, Jingjuan Zhu, Na Zhou, Jing Cong & Xiaochun Zhang
Pages: 4109-4118
Published online: 07 May 2019
AbstractforThe safety and serious adverse events of approved ALK inhibitors in malignancies: a meta-analysis | Full Text | References | PDF (1.5 MB) | EPUB
  • 148 Views
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Article
Comparative efficacy of targeted maintenance therapy for newly diagnosed epithelial ovarian cancer: a network meta-analysis
Xiaoyu Xu, Songcheng Yin, Hongling Guo, Mengxiong Li, Zhirong Qian, Xiaohui Tian & Tian Li
Pages: 4119-4128
Published online: 07 May 2019
AbstractforComparative efficacy of targeted maintenance therapy for newly diagnosed epithelial ovarian cancer: a network meta-analysis | Full Text | References | PDF (1.3 MB) | EPUB
  • 67 Views
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Article
Acute myeloid leukemia patient with FLT3-ITD and NPM1 double mutation should undergo allogeneic hematopoietic stem cell transplantation in CR1 for better prognosis 
Yan Huang, Juan Hu, Ting Lu, Yi Luo, Jimin Shi, Wenjun Wu, Xiaoyan Han, Weiyan Zheng, Jingsong He, Zhen Cai, Guoqing Wei, He Huang & Jie Sun
Pages: 4129-4142
Published online: 08 May 2019
AbstractforAcute myeloid leukemia patient with FLT3-ITD and NPM1 double mutation should undergo allogeneic hematopoietic stem cell transplantation in CR1 for better prognosis  | Full Text | References | PDF (994.2 KB) | EPUB
  • 106 Views
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Article
Short-term benefit of neoadjuvant hormone therapy in patients with localized high-risk or limited progressive prostate cancer
Bing-Lei Ma, Lin Yao, Yu Fan, Yu Wang, Yi-Sen Meng, Qian Zhang, Zhi-Song He, Jie Jin & Li-Qun Zhou
Pages: 4143-4151
Published online: 10 May 2019
AbstractforShort-term benefit of neoadjuvant hormone therapy in patients with localized high-risk or limited progressive prostate cancer | Full Text | References | PDF (471.9 KB) | EPUB
  • 59 Views
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Article
A novel LARCassigner3 classification predicts outcomes in patients with locally advanced rectal cancer treated with neoadjuvant chemoradiotherapy: a retrospective training and validation analysis
Jing Zhang, Lijun Shen, Yun Deng, Xiaoyang Sun, Yaqi Wang, Ye Yao, Hui Zhang, Wei Zou, Zhiyuan Zhang, Juefeng Wan, Lifeng Yang, Ji Zhu & Zhen Zhang
Pages: 4153-4170
Published online: 07 May 2019
AbstractforA novel LARCassigner3 classification predicts outcomes in patients with locally advanced rectal cancer treated with neoadjuvant chemoradiotherapy: a retrospective training and validation analysis | Full Text | References | PDF (1 MB) | EPUB
  • 53 Views
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Article
Clinicopathological and prognostic value of PD-L1 in urothelial carcinoma: a meta-analysis
Xiangli Ding, Qiaochao Chen, Zhao Yang, Jun Li, Hui Zhan, Nihong Lu, Min Chen, Yanlong Yang, Jiansong Wang & Delin Yang
Pages: 4171-4184
Published online: 08 May 2019
AbstractforClinicopathological and prognostic value of PD-L1 in urothelial carcinoma: a meta-analysis | Full Text | References | PDF (2.2 MB) | EPUB
  • 132 Views
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Article
Clinical significance of systemic immune-inflammation index (SII) and C-reactive protein-to-albumin ratio (CAR) in patients with esophageal cancer: a meta-analysis
Yi Zhang, Guoliang Xiao & Rong Wang
Pages: 4185-4200
Published online: 07 May 2019
AbstractforClinical significance of systemic immune-inflammation index (SII) and C-reactive protein-to-albumin ratio (CAR) in patients with esophageal cancer: a meta-analysis | Full Text | References | PDF (2.3 MB) | EPUB
  • 161 Views
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Article
Successful postoperative recovery management after thoracoscopic lobectomy and segmentectomy using an ERAS-based protocol of immediate ice cream intake and early ambulation: a 3-year study
Hiroaki Kuroda, Yusuke Sugita, Kiyoe Watanabe, Keita Nakanishi, Noriaki Sakakura, Yumiko Naito & Yukinori Sakao
Pages: 4201-4207
Published online: 07 May 2019
AbstractforSuccessful postoperative recovery management after thoracoscopic lobectomy and segmentectomy using an ERAS-based protocol of immediate ice cream intake and early ambulation: a 3-year study | Full Text | References | PDF (329.8 KB) | EPUB
  • 111 Views
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Article
Long noncoding RNA DLX6-AS1 promotes tumorigenesis by modulating miR-497-5p/FZD4/FZD6/Wnt/β-catenin pathway in pancreatic cancer
Jiyong Yang, Zhen Ye, Dan Mei, Honggang Gu & Jingzhe Zhang
Pages: 4209-4221
Published online: 07 May 2019
AbstractforLong noncoding RNA DLX6-AS1 promotes tumorigenesis by modulating miR-497-5p/FZD4/FZD6/Wnt/β-catenin pathway in pancreatic cancer | Full Text | References | PDF (4.8 MB) | EPUB
  • 80 Views
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Article
A comprehensive analysis of the factors of positive pelvic lymph nodes on survival of cervical cancer patients with 2018 FIGO stage IIIC1p
Ding-Ding Yan, Qiu Tang, Ye-Qiang Tu, Jian-Hong Chen & Xiao-Juan Lv
Pages: 4223-4230
Published online: 07 May 2019
AbstractforA comprehensive analysis of the factors of positive pelvic lymph nodes on survival of cervical cancer patients with 2018 FIGO stage IIIC1p | Full Text | References | PDF (488.5 KB) | EPUB
  • 66 Views
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Review

Review Article
Cytoreductive surgery with hyperthermic intraperitoneal chemotherapy for peritoneal mesothelioma: patient selection and special considerations
Laura M Enomoto, Perry Shen, Edward A Levine & Konstantinos I Votanopoulos
Pages: 4231-4241
Published online: 07 May 2019
AbstractforCytoreductive surgery with hyperthermic intraperitoneal chemotherapy for peritoneal mesothelioma: patient selection and special considerations | Full Text | References | PDF (2.3 MB) | EPUB
  • 92 Views
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Original Research

Article
Prognostic significance of peripheral blood absolute lymphocyte count and derived neutrophil to lymphocyte ratio in patients with newly diagnosed extranodal natural killer/T-cell lymphoma
Xiangxiang Zhou, Xiaogang Sun, Wenbo Zhao, Xiaosheng Fang & Xin Wang
Pages: 4243-4254
Published online: 07 May 2019
AbstractforPrognostic significance of peripheral blood absolute lymphocyte count and derived neutrophil to lymphocyte ratio in patients with newly diagnosed extranodal natural killer/T-cell lymphoma | Full Text | References | PDF (1.2 MB) | EPUB
  • 48 Views
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Article
Survival and intracranial control outcomes of whole-brain radiotherapy (WBRT) alone versus WBRT plus a radiotherapy boost in non-small-cell lung cancer with brain metastases: a single-institution retrospective analysis
Fei Lu, Yu Hou, Yaoxiong Xia, Lan Li, Li Wang, Ke Cao, Haixia Chen, Li Chang & Wenhui Li
Pages: 4255-4272
Published online: 08 May 2019
AbstractforSurvival and intracranial control outcomes of whole-brain radiotherapy (WBRT) alone versus WBRT plus a radiotherapy boost in non-small-cell lung cancer with brain metastases: a single-institution retrospective analysis | Full Text | References | PDF (1.3 MB) | EPUB
  • 59 Views
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Review

Review Article
Gonadotropin-releasing hormone agonists during chemotherapy for ovarian function and fertility preservation for patients with early-stage breast cancer
Hikmat Abdel-Razeq
Pages: 4273-4282
Published online: 08 May 2019
AbstractforGonadotropin-releasing hormone agonists during chemotherapy for ovarian function and fertility preservation for patients with early-stage breast cancer | Full Text | References | PDF (242.9 KB) | EPUB
  • 167 Views
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Article
Clinicopathological and prognostic significance of pretreatment thrombocytosis in patients with endometrial cancer: a meta-analysis
Yi-Yang Bai, Lan Du, Li Jing, Tao Tian, Xuan Liang, Min Jiao, Ke-Jun Nan, Hui Guo & Zhi-Ping Ruan
Pages: 4283-4295
Published online: 08 May 2019
AbstractforClinicopathological and prognostic significance of pretreatment thrombocytosis in patients with endometrial cancer: a meta-analysis | Full Text | References | PDF (898.3 KB) | EPUB
  • 73 Views
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Review

Review Article
Clinical utility of pembrolizumab in the management of advanced solid tumors: an evidence-based review on the emerging new data
Pauline du Rusquec, Ombline de Calbiac, Marie Robert, Mario Campone & Jean Sebastien Frenel
Pages: 4297-4312
Published online: 15 May 2019
AbstractforClinical utility of pembrolizumab in the management of advanced solid tumors: an evidence-based review on the emerging new data | Full Text | References | PDF (566.1 KB) | EPUB
  • 174 Views
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Article
Circulating microRNA as diagnostic biomarkers for haematological cancers: a systematic review and meta-analysis
Emmanuel Kwateng Drokow, Kai Sun, Hafiz Abdul Waqas Ahmed, Gloria Selorm Akpabla, Juanjuan Song & Mingyue Shi
Pages: 4313-4326
Published online: 10 May 2019
AbstractforCirculating microRNA as diagnostic biomarkers for haematological cancers: a systematic review and meta-analysis | Full Text | References | PDF (5 MB) | EPUB
  • 127 Views
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Article
Prevention effect of low-temperature atomization inhalation for radiation induced oral mucositis in patients with head and neck cancer undergoing radiotherapy
Xing-Hua Bai, Zi-Min Chen, Liang-Hua Ma, Zheng He & Guang Li
Pages: 4327-4333
Published online: 09 May 2019
AbstractforPrevention effect of low-temperature atomization inhalation for radiation induced oral mucositis in patients with head and neck cancer undergoing radiotherapy | Full Text | References | PDF (212.1 KB) | EPUB
  • 61 Views
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Article
Clinical relevance and significance of programmed death-ligand 1 expression, tumor-infiltrating lymphocytes, and p16 status in sinonasal squamous cell carcinoma
Huatao Quan, Li Yan, Shuyi Wang & Shengzi Wang
Pages: 4335-4345
Published online: 09 May 2019
AbstractforClinical relevance and significance of programmed death-ligand 1 expression, tumor-infiltrating lymphocytes, and p16 status in sinonasal squamous cell carcinoma | Full Text | References | PDF (1.4 MB) | EPUB
  • 63 Views
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Article
Prevalence and risk factors of anxiety and depression in Chinese patients with lung cancer：a cross-sectional study
Xiaoru Yan, Xun Chen, Meng Li & Peitong Zhang
Pages: 4347-4356
Published online: 09 May 2019
AbstractforPrevalence and risk factors of anxiety and depression in Chinese patients with lung cancer：a cross-sectional study | Full Text | References | PDF (264.1 KB) | EPUB
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Article
Prognostic role of a new inflammatory index with neutrophil-to-lymphocyte ratio and lactate dehydrogenase (CII: Colon Inflammatory Index) in patients with metastatic colorectal cancer: results from the randomized Italian Trial in Advanced Colorectal Cancer (ITACa) study
Andrea Casadei-Gardini, Emanuela Scarpi, Paola Ulivi, Maria Angela Palladino, Caterina Accettura, Ilaria Bernardini, Andrea Spallanzani, Fabio Gelsomino, Jody Corbelli, Giorgia Marisi, Silvia Ruscelli, Martina Valgiusti, Giovanni Luca Frassineti & Alessandro Passardi
Pages: 4357-4369
Published online: 10 May 2019
AbstractforPrognostic role of a new inflammatory index with neutrophil-to-lymphocyte ratio and lactate dehydrogenase (CII: Colon Inflammatory Index) in patients with metastatic colorectal cancer: results from the randomized Italian Trial in Advanced Colorectal Cancer (ITACa) study | Full Text | References | PDF (1.7 MB) | EPUB
  • 86 Views
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Review

Article
Current status and future prospects of PARP inhibitor clinical trials in ovarian cancer
Xuan Jiang, Weihua Li, Xiaoying Li, Huimin Bai & Zhenyu Zhang
Pages: 4371-4390
Published online: 10 May 2019
AbstractforCurrent status and future prospects of PARP inhibitor clinical trials in ovarian cancer | Full Text | References | PDF (319 KB) | EPUB
  • 378 Views
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Original Research

Article
Elevated nuclear YBX1 expression and the clinicopathological characteristics of patients with solid tumors: a meta-analysis
Chunze Zhang, Tingting Yin, Ran Tao, Bo Xiao, Jing Chen, Zixuan Li, Xueyuan Miao, Qing Peng, Liu Sun, Weihua Zhang, Junxu Ren, Zhao Zhang, Ying Zhang, Xichuan Li & Wei Zhang
Pages: 4391-4402
Published online: 14 May 2019
AbstractforElevated nuclear YBX1 expression and the clinicopathological characteristics of patients with solid tumors: a meta-analysis | Full Text | References | PDF (2.3 MB) | EPUB
  • 64 Views
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Article
Development and external validation of a nomogram for predicting the overall survival of patients with stage II nasopharyngeal carcinoma after curative treatment
Sha-Sha He, Cheng-Tao Wang, Zhen-Wei Peng, Yu-Feng Ren, Li-Xia Lu, Rui-Wan Chen, Shao-Bo Liang, Yan Wang & Yong Chen
Pages: 4403-4412
Published online: 10 May 2019
AbstractforDevelopment and external validation of a nomogram for predicting the overall survival of patients with stage II nasopharyngeal carcinoma after curative treatment | Full Text | References | PDF (1.1 MB) | EPUB
  • 59 Views
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Review

Review Article
Tissue-specific and exosomal miRNAs in lung cancer radiotherapy: from regulatory mechanisms to clinical implications
Long Long, Xue Zhang, Jian Bai, Yizhou Li, Xiaolong Wang & Yunfeng Zhou
Pages: 4413-4424
Published online: 13 May 2019
AbstractforTissue-specific and exosomal miRNAs in lung cancer radiotherapy: from regulatory mechanisms to clinical implications | Full Text | References | PDF (1.8 MB) | EPUB
  • 120 Views
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Original Research

Article
Long noncoding RNA FEZF1-AS1 promotes the motility of esophageal squamous cell carcinoma through Wnt/β-catenin pathway
Lijun Yang, Yafei Ye, Jie Chu, Jinlin Jia, Yunhui Qu, Ting Sun, Huiqing Yin, Liang Ming, Junhu Wan & Fucheng He
Pages: 4425-4435
Published online: 13 May 2019
AbstractforLong noncoding RNA FEZF1-AS1 promotes the motility of esophageal squamous cell carcinoma through Wnt/β-catenin pathway | Full Text | References | PDF (4.3 MB) | EPUB
  • 63 Views
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Article
Effective prevention of sorafenib-related vascular damage induced adverse events and maintenance of hepatic function by dried bonito broth and histidine
Norihiro Sakai, Kenya Kamimura, Yoko Shinagawa-Kobayashi, Takuro Nagoya, Yusuke Niwa, Masayoshi Ko, Toru Setsu, Akira Sakamaki, Takeshi Yokoo, Satoshi Abe, Hiroteru Kamimura, Soichi Sugitani, Masahiko Yanagi & Shuji Terai
Pages: 4437-4448
Published online: 13 May 2019
AbstractforEffective prevention of sorafenib-related vascular damage induced adverse events and maintenance of hepatic function by dried bonito broth and histidine | Full Text | References | PDF (2.7 MB) | EPUB
  • 60 Views
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Article
Safety, tolerability, and pharmacokinetics of simotinib, a novel specific EGFR tyrosine kinase inhibitor, in patients with advanced non-small cell lung cancer: results of a phase Ib trial
Xing-Sheng Hu, Xiao-Hong Han, Sheng Yang, Ning Li, Lin Wang, Yuan-Yuan Song, Hua Mu & Yuan-Kai Shi
Pages: 4449-4459
Published online: 13 May 2019
AbstractforSafety, tolerability, and pharmacokinetics of simotinib, a novel specific EGFR tyrosine kinase inhibitor, in patients with advanced non-small cell lung cancer: results of a phase Ib trial | Full Text | References | PDF (877 KB) | EPUB
  • 63 Views
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Article
Prognostic significance of perineural invasion in vulvar squamous cell carcinoma
Ying Long, De-Sheng Yao, You-Sheng Wei, Chang-Hong Wei & Xiao-Yu Chen
Pages: 4461-4469
Published online: 14 May 2019
AbstractforPrognostic significance of perineural invasion in vulvar squamous cell carcinoma | Full Text | References | PDF (650 KB) | EPUB
  • 63 Views
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Article
Prognostic significance of systemic immune-inflammation index in triple-negative breast cancer
Jingxin Liu, Zhangzhen Shi, Yuansong Bai, Lin Liu & Kailiang Cheng
Pages: 4471-4480
Published online: 14 May 2019
AbstractforPrognostic significance of systemic immune-inflammation index in triple-negative breast cancer | Full Text | References | PDF (947.3 KB) | EPUB
  • 118 Views
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Article
Upregulation of LSD1 promotes migration and invasion in gastric cancer through facilitating EMT
Jin Zhang, Donghui Zhao, Qingjun Li, Xiuluan Du, Yanxiang Liu, Xin Dai & Lianqing Hong
Pages: 4481-4491
Published online: 15 May 2019
AbstractforUpregulation of LSD1 promotes migration and invasion in gastric cancer through facilitating EMT | Full Text | References | PDF (2.2 MB) | EPUB
  • 80 Views
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Article
Impact of taste and smell training on taste disorders during chemotherapy – TASTE trial
Julia von Grundherr, Barbara Koch, Donata Grimm, Jannike Salchow, Luzia Valentini, Thomas Hummel, Carsten Bokemeyer, Alexander Stein & Julia Mann
Pages: 4493-4504
Published online: 16 May 2019
AbstractforImpact of taste and smell training on taste disorders during chemotherapy – TASTE trial | Full Text | References | PDF (486.7 KB) | EPUB
  • 275 Views
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Article
The lncRNA HOXA11-AS regulates Rab3D expression by sponging miR-125a-5p promoting metastasis of osteosarcoma
Kun Cao, Yueyang Fang, Hao Wang, Zheng Jiang, Li Guo & Yong Hu
Pages: 4505-4518
Published online: 16 May 2019
AbstractforThe lncRNA HOXA11-AS regulates Rab3D expression by sponging miR-125a-5p promoting metastasis of osteosarcoma | Full Text | References | PDF (15.8 MB) | EPUB
  • 69 Views
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Review

Review Article
Profile of pembrolizumab in the treatment of patients with unresectable or metastatic urothelial carcinoma
Junichi Inokuchi & Masatoshi Eto
Pages: 4519-4528
Published online: 15 May 2019
AbstractforProfile of pembrolizumab in the treatment of patients with unresectable or metastatic urothelial carcinoma | Full Text | References | PDF (277.3 KB) | EPUB
  • 76 Views
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Original Research

Article
The oncoprotein HBXIP facilitates metastasis of hepatocellular carcinoma cells by activation of MMP15 expression
Sen Zheng, Huita Wu, Fei Wang, Jie Lv, Jing Lu, Qinliang Fang, Fuqiang Wang, Yuyan Lu, Sheng Zhang, Yaping Xu, Qing Bao, Chengrong Xie & Zhenyu Yin
Pages: 4529-4540
Published online: 16 May 2019
AbstractforThe oncoprotein HBXIP facilitates metastasis of hepatocellular carcinoma cells by activation of MMP15 expression | Full Text | References | PDF (5.6 MB) | EPUB
  • 65 Views
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Case Report

Review Article
Cardiac toxicity of immune-checkpoint inhibitors: a clinical case of nivolumab-induced myocarditis and review of the evidence and new challenges
Roberto Martin Huertas, Cristina Saavedra Serrano, Cristian Perna, Ana Ferrer Gómez & Teresa Alonso Gordoa
Pages: 4541-4548
Published online: 16 May 2019
AbstractforCardiac toxicity of immune-checkpoint inhibitors: a clinical case of nivolumab-induced myocarditis and review of the evidence and new challenges | Full Text | References | PDF (1.2 MB) | EPUB
  • 150 Views
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Original Research

Article
The value of the plasma circulating cell-free DNA concentration and integrity index as a clinical tool for prostate cancer diagnosis: a prospective case–control cohort study in an Iranian population
Maryam Khani, Jalil Hosseini, Reza Mirfakhraie, Mohsen Habibi, Eznollah Azargashb & Farkhondeh Pouresmaeili
Pages: 4549-4556
Published online: 16 May 2019
AbstractforThe value of the plasma circulating cell-free DNA concentration and integrity index as a clinical tool for prostate cancer diagnosis: a prospective case–control cohort study in an Iranian population | Full Text | References | PDF (446 KB) | EPUB
  • 96 Views
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Article
Clinicopathological features and prognosis of AFP-producing colorectal cancer: a single-center analysis of 20 cases
Fei Ren, Weiwei Weng, Qiongyan Zhang, Cong Tan, Midie Xu, Meng Zhang, Lei Wang, Weiqi Sheng, Shujuan Ni & Dan Huang
Pages: 4557-4567
Published online: 16 May 2019
AbstractforClinicopathological features and prognosis of AFP-producing colorectal cancer: a single-center analysis of 20 cases | Full Text | References | PDF (1.9 MB) | EPUB
  • 123 Views
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Article
The opposite role of alternatively spliced isoforms of LINC00477 in gastric cancer
Hongchao Zhao, Yuanhang He, Haohao Li, Ali Zhu, Yanwei Ye, Guanghui Liu, Chunlin Zhao & Xiefu Zhang
Pages: 4569-4576
Published online: 16 May 2019
AbstractforThe opposite role of alternatively spliced isoforms of LINC00477 in gastric cancer | Full Text | References | PDF (1.3 MB) | EPUB
  • 77 Views
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Article
NSE from diffuse large B-cell lymphoma cells regulates macrophage polarization
Meng-yuan Zhu, Wen-jian Liu, Hua Wang, Wei-da Wang, Na-wei Liu & Yue Lu
Pages: 4577-4595
Published online: 17 May 2019
AbstractforNSE from diffuse large B-cell lymphoma cells regulates macrophage polarization | Full Text | References | PDF (6 MB) | EPUB
  • 85 Views
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Article
Expression of PD-L1 in cervical carcinoma and its impact on survival associated with T-cell infiltration and FoxP3 expression
Rafael M Grochot, Janaína Brollo, Floriano Riva Neto, Aline C Tregnago, Cassiano Scholze, Rui Norris, Sargeele Silva, Débora C Weschenfelder, André B Reiriz, Lessandra Michelin & Fábio F Pasqualotto
Pages: 4597-4605
Published online: 17 May 2019
AbstractforExpression of PD-L1 in cervical carcinoma and its impact on survival associated with T-cell infiltration and FoxP3 expression | Full Text | References | PDF (1.3 MB) | EPUB
  • 77 Views
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Article
Does the radiologist need to rescan the breast lesion to validate the final BI-RADS US assessment made on the static images in the diagnostic setting?
Yue Hu, Jingsi Mei, Xiaofang Jiang, Ran Gu, Fengtao Liu, Yaping Yang, Hongli Wang, Shiyu Shen, Haixia Jia, Qiang Liu & Chang Gong
Pages: 4607-4615
Published online: 22 May 2019
AbstractforDoes the radiologist need to rescan the breast lesion to validate the final BI-RADS US assessment made on the static images in the diagnostic setting? | Full Text | References | PDF (747.8 KB) | EPUB
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Corrigendum

Correction
Disulfiram inhibits epithelial–mesenchymal transition through TGFβ–ERK–Snail pathway independently of Smad4 to decrease oral squamous cell carcinoma metastasis [Corrigendum]
Page: 4617
Published online: 22 May 2019
CitationforDisulfiram inhibits epithelial–mesenchymal transition through TGFβ–ERK–Snail pathway independently of Smad4 to decrease oral squamous cell carcinoma metastasis [Corrigendum] | Full Text | PDF (149.9 KB) | EPUB
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Review

Review Article
Efficacy and safety of programmed death 1 inhibitors in patients with advanced non-small cell lung cancer: a meta-analysis
Yi Liu, Sijing Zhou, Yongsheng Du, Li Sun, Huihui Jiang, Binbin Zhang, Gengyun Sun & Ran Wang
Pages: 4619-4630
Published online: 21 May 2019
AbstractforEfficacy and safety of programmed death 1 inhibitors in patients with advanced non-small cell lung cancer: a meta-analysis | Full Text | References | PDF (2.7 MB) | EPUB
  • 60 Views
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Original Research

Article
Metabolic profile and structure–activity relationship of resveratrol and its analogs in human bladder cancer cells
Yang Yang, Guangyuan Zhang, Chuangang Li, Sihan Wang, Manning Zhu, Jinan Wang, Hangtian Yue, Xiaodong Ma, Yuhong Zhen & Xiaohong Shu
Pages: 4631-4642
Published online: 21 May 2019
AbstractforMetabolic profile and structure–activity relationship of resveratrol and its analogs in human bladder cancer cells | Full Text | References | PDF (2.6 MB) | EPUB
  • 113 Views
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Article
Upregulation of long noncoding RNA LINC00152 promotes proliferation and metastasis of esophageal squamous cell carcinoma
Yi Yang, Xiangwei Sun, Chuang Chi, Yu Liu, Chaoxi Lin, Deyao Xie, Xian Shen & Xiaoming Lin
Pages: 4643-4654
Published online: 21 May 2019
AbstractforUpregulation of long noncoding RNA LINC00152 promotes proliferation and metastasis of esophageal squamous cell carcinoma | Full Text | References | PDF (4.5 MB) | EPUB
  • 71 Views
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Article
Estrogen-dependent disruption of intracellular iron metabolism augments the cytotoxic effects of doxorubicin in select breast and ovarian cancer cells
Khuloud Bajbouj, Jasmin Shafarin & Mawieh Hamad
Pages: 4655-4668
Published online: 23 May 2019
AbstractforEstrogen-dependent disruption of intracellular iron metabolism augments the cytotoxic effects of doxorubicin in select breast and ovarian cancer cells | Full Text | References | PDF (4.1 MB) | EPUB
  • 93 Views
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Article
Whole-brain helical tomotherapy with integrated boost for brain metastases in patients with malignant melanoma – final results of the BRAIN-RT trial
Henrik Hauswald, Denise Bernhardt, David Krug, Sonja Katayama, Gregor Habl, Justo Lorenzo Bermejo, Jürgen Debus & Florian Sterzing
Pages: 4669-4676
Published online: 24 May 2019
AbstractforWhole-brain helical tomotherapy with integrated boost for brain metastases in patients with malignant melanoma – final results of the BRAIN-RT trial | Full Text | References | PDF (364.1 KB) | EPUB
  • 64 Views
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Article
Expression of CD133 and CD24 and their different phenotypes in urinary bladder carcinoma
Rola M Farid, Sanaa Abd-Elmaged Sammour, Zeinab Abdelkader Shehab ElDin, Manal Ibrahim Salman & Tag Ibrahim Omran
Pages: 4677-4690
Published online: 23 May 2019
AbstractforExpression of CD133 and CD24 and their different phenotypes in urinary bladder carcinoma | Full Text | References | PDF (1.6 MB) | EPUB
  • 103 Views
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Article
Elevated expression of CXCL16 correlates with poor prognosis in patients with colorectal cancer
Zhihui Chen, Weigang Dai, Liang Yang, Hong Yang, Li Ding, Yulong He, Xinming Song & Ji Cui
Pages: 4691-4697
Published online: 23 May 2019
AbstractforElevated expression of CXCL16 correlates with poor prognosis in patients with colorectal cancer | Full Text | References | PDF (947.7 KB) | EPUB
  • 62 Views
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Review

Review Article
Trastuzumab treatment after progression in HER2-positive metastatic breast cancer following relapse of trastuzumab-based regimens: a meta-analysis
Yiqun Han, Jiayu Wang, Weiming Liu, Peng Yuan, Qing Li, Pin Zhang, Fei Ma, Yang Luo, Ying Fan, Shanshan Chen, Ruigang Cai, Qiao Li & Binghe Xu
Pages: 4699-4706
Published online: 23 May 2019
AbstractforTrastuzumab treatment after progression in HER2-positive metastatic breast cancer following relapse of trastuzumab-based regimens: a meta-analysis | Full Text | References | PDF (1.3 MB) | EPUB
  • 69 Views
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Original Research

Article
Voltage-dependent calcium channel α2δ1 subunit is a specific candidate marker for identifying gastric cancer stem cells
Ziran Zhang, Wei Zhao, Xiaoting Lin, Jing Gao, Zhiqian Zhang & Lin Shen
Pages: 4707-4718
Published online: 23 May 2019
AbstractforVoltage-dependent calcium channel α2δ1 subunit is a specific candidate marker for identifying gastric cancer stem cells | Full Text | References | PDF (2.7 MB) | EPUB
  • 80 Views
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Article
A novel preoperative plasma indicator to predict prognoses for patients with esophageal squamous cell carcinoma after radical esophagectomy: fibrinogen-to-lymphocyte ratio
Ningbo Fan, Dongni Chen, Jiabo Zheng, Zhesheng Wen & Peng Lin
Pages: 4719-4728
Published online: 23 May 2019
AbstractforA novel preoperative plasma indicator to predict prognoses for patients with esophageal squamous cell carcinoma after radical esophagectomy: fibrinogen-to-lymphocyte ratio | Full Text | References | PDF (456.7 KB) | EPUB
  • 51 Views
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Article
miR-142-3p suppresses uveal melanoma by targeting CDC25C, TGFβR1, GNAQ, WASL, and RAC1
Dewei Peng, Jing Dong, Yunping Zhao, Xiaomei Peng, Jingjing Tang, Xiaoyan Chen, Lihua Wang, Dan-Ning Hu, Peter S Reinach, Jia Qu & Dongsheng Yan
Pages: 4729-4742
Published online: 24 May 2019
AbstractformiR-142-3p suppresses uveal melanoma by targeting CDC25C, TGFβR1, GNAQ, WASL, and RAC1 | Full Text | References | PDF (4.2 MB) | EPUB
  • 92 Views
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Article
TLR4 expression correlated with PD-L1 expression indicates a poor prognosis in patients with peripheral T-cell lymphomas
Shu Zhao, Mengqi Sun, Hongxue Meng, Hongfei Ji, Yupeng Liu, Minghui Zhang, Hongbin Li, Pengfei Li, Yue Zhang & Qingyuan Zhang
Pages: 4743-4756
Published online: 23 May 2019
AbstractforTLR4 expression correlated with PD-L1 expression indicates a poor prognosis in patients with peripheral T-cell lymphomas | Full Text | References | PDF (2.6 MB) | EPUB
  • 73 Views
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Article
A panel of collagen genes are associated with prognosis of patients with gastric cancer and regulated by microRNA-29c-3p: an integrated bioinformatics analysis and experimental validation
Qiang-Nu Zhang, Hui-Li Zhu, Meng-Ting Xia, Juan Liao, Xiao-Tao Huang, Jiang-Wei Xiao & Cong Yuan
Pages: 4757-4772
Published online: 24 May 2019
AbstractforA panel of collagen genes are associated with prognosis of patients with gastric cancer and regulated by microRNA-29c-3p: an integrated bioinformatics analysis and experimental validation | Full Text | References | PDF (3.7 MB) | EPUB
  • 98 Views
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Article
An efficient method that combines the ThinPrep cytologic test with E6/E7 mRNA testing for cervical cancer screening
Dan Pan, Chan-Qiong Zhang, Qi-Lian Liang & Xiao-Cui Hong
Pages: 4773-4780
Published online: 24 May 2019
AbstractforAn efficient method that combines the ThinPrep cytologic test with E6/E7 mRNA testing for cervical cancer screening | Full Text | References | PDF (242.7 KB) | EPUB
  • 88 Views
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Article
Eupatilin inhibits glioma proliferation, migration, and invasion by arresting cell cycle at G1/S phase and disrupting the cytoskeletal structure
Xiaowei Fei, Ji Wang, Chen Chen, Boyun Ding, Xiaojun Fu, Wenjing Chen, Chongwu Wang & Ruxiang Xu
Pages: 4781-4796
Published online: 24 May 2019
AbstractforEupatilin inhibits glioma proliferation, migration, and invasion by arresting cell cycle at G1/S phase and disrupting the cytoskeletal structure | Full Text | References | PDF (5.6 MB) | EPUB
  • 77 Views
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Article
DCZ0814 induces apoptosis and G0/G1 phase cell cycle arrest in myeloma by dual inhibition of mTORC1/2
Yuanyuan Kong, Bo Li, Shuaikang Chang, Lu Gao, Zhijian Xu, Wan He, Guang Yang, Bingqian Xie, Gege Chen, Liangning Hu, Kang Lu, Yingcong Wang, Xiaosong Wu, Weiliang Zhu & Jumei Shi
Pages: 4797-4808
Published online: 27 May 2019
AbstractforDCZ0814 induces apoptosis and G0/G1 phase cell cycle arrest in myeloma by dual inhibition of mTORC1/2 | Full Text | References | PDF (3.9 MB) | EPUB
  • 69 Views
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Article
Prognostic impact of the pretreatment albumin to alkaline phosphatase ratio for nonmetastatic breast cancer patients
Zhi-Qing Long, Xin Hua, Wen-Wen Zhang, Shao-Wen Lv, Jia-Peng Deng, Ling Guo, Zhen-Yu He & Huan-Xin Lin
Pages: 4809-4814
Published online: 27 May 2019
AbstractforPrognostic impact of the pretreatment albumin to alkaline phosphatase ratio for nonmetastatic breast cancer patients | Full Text | References | PDF (345.6 KB) | EPUB
  • 125 Views
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Article
Selective use of concurrent chemotherapy in elderly cervical cancer patients treated with definitive radiotherapy: experience from two institutions
Kai-yun You, Hai-hua Peng, Yan-hui Jiang, Zhuo-fei Bi & Xing-sheng Qiu
Pages: 4815-4823
Published online: 27 May 2019
AbstractforSelective use of concurrent chemotherapy in elderly cervical cancer patients treated with definitive radiotherapy: experience from two institutions | Full Text | References | PDF (507.5 KB) | EPUB
  • 70 Views
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Article
MiR-193a-3p inhibits pancreatic ductal adenocarcinoma cell proliferation by targeting CCND1
Zhi-Min Chen, Qiao Yu, Gang Chen, Rui-Xue Tang, Dian-Zhong Luo, Yi-Wu Dang & Dan-Ming Wei
Pages: 4825-4837
Published online: 27 May 2019
AbstractforMiR-193a-3p inhibits pancreatic ductal adenocarcinoma cell proliferation by targeting CCND1 | Full Text | References | PDF (4 MB) | EPUB
  • 81 Views
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Article
Safety of early oral feeding after total laparoscopic radical gastrectomy for gastric cancer (SOFTLY-1): a single-center randomized controlled trial
Quan Wang, Ke-Lu Yang, Bo-Yang Guo, Li-Feng Shang, Zun-Dong Yan, Juan Yu, Di Zhang & Gang Ji
Pages: 4839-4846
Published online: 29 May 2019
AbstractforSafety of early oral feeding after total laparoscopic radical gastrectomy for gastric cancer (SOFTLY-1): a single-center randomized controlled trial | Full Text | References | PDF (488.1 KB) | EPUB
  • 83 Views
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Article
Intra-rectal use of epinephrine in radiotherapy of prostate cancer
Shang-Bin Qin, Xian-Shu Gao, Hong-Zhen Li, Chao-Xing Liu, Dong-Liang Hou, Wei-Dong Nian, Xue-Ying Li & Dian Wang
Pages: 4847-4854
Published online: 27 May 2019
AbstractforIntra-rectal use of epinephrine in radiotherapy of prostate cancer | Full Text | References | PDF (553.7 KB) | EPUB
  • 73 Views
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Article
Adjuvant chemoradiotherapy versus adjuvant chemotherapy for patients with N3 gastric cancer after D2/R0 resection: a retrospective study based on propensity score analyses
Meng-Long Zhou, Wang Yang, Ya-Qi Wang, Miao Mo, Ran Hu, Yan Wang, Jia-Ning Yang, Gui-Chao Li, Ya-Nong Wang & Zhen Zhang
Pages: 4855-4870
Published online: 28 May 2019
AbstractforAdjuvant chemoradiotherapy versus adjuvant chemotherapy for patients with N3 gastric cancer after D2/R0 resection: a retrospective study based on propensity score analyses | Full Text | References | PDF (2.2 MB) | EPUB
  • 59 Views
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Article
Dihydrodiosgenin inhibits endothelial cell-derived factor VIII and platelet-mediated hepatocellular carcinoma metastasis
Manjiao Zhuang, Guang Xin, Zeliang Wei, Shiyi Li, Zhihua Xing, Chengjie Ji, Junrong Du, Hai Niu & Wen Huang
Pages: 4871-4882
Published online: 31 May 2019
AbstractforDihydrodiosgenin inhibits endothelial cell-derived factor VIII and platelet-mediated hepatocellular carcinoma metastasis | Full Text | References | PDF (3.4 MB) | EPUB
  • 69 Views
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Article
Impact of EGFR genotype on the efficacy of osimertinib in EGFR tyrosine kinase inhibitor-resistant patients with non-small cell lung cancer: a prospective observational study
Satoshi Igawa, Taihei Ono, Masashi Kasajima, Mikiko Ishihara, Yasuhiro Hiyoshi, Seiichiro Kusuhara, Noriko Nishinarita, Tomoya Fukui, Masaru Kubota, Jiichiro Sasaki, Mitsufuji Hisashi, Masanori Yokoba, Masato Katagiri & Katsuhiko Naoki
Pages: 4883-4892
Published online: 28 May 2019
AbstractforImpact of EGFR genotype on the efficacy of osimertinib in EGFR tyrosine kinase inhibitor-resistant patients with non-small cell lung cancer: a prospective observational study | Full Text | References | PDF (337.7 KB) | EPUB
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Review

Review Article
Nivolumab plus ipilimumab combination therapy for the first-line treatment NSCLC: evidence to date
Jordi Remon, Laura Esteller & Álvaro Taus
Pages: 4893-4904
Published online: 29 May 2019
AbstractforNivolumab plus ipilimumab combination therapy for the first-line treatment NSCLC: evidence to date | Full Text | References | PDF (352.8 KB) | EPUB
  • 126 Views
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Clinical Trial Report

Apatinib enhances chemosensitivity of gastric cancer to paclitaxel and 5-fluorouracil
Zhiyuan Xu, Can Hu, Shangqi Chen, Chunli Zhang, Jianfa Yu, Xiaofeng Wang, Hang Lv & Xiangdong Cheng
Pages: 4905-4915
Published online: 29 May 2019
AbstractforApatinib enhances chemosensitivity of gastric cancer to paclitaxel and 5-fluorouracil | Full Text | References | PDF (1.8 MB) | EPUB
  • 89 Views
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Original Research

Article
Apolipoprotein C1 (APOC1) promotes tumor progression via MAPK signaling pathways in colorectal cancer
Hui Ren, Zhihui Chen, Liang Yang, Weixin Xiong, Hong Yang, Kaiwu Xu, Ertao Zhai, Li Ding, Yulong He & Xingming Song
Pages: 4917-4930
Published online: 29 May 2019
AbstractforApolipoprotein C1 (APOC1) promotes tumor progression via MAPK signaling pathways in colorectal cancer | Full Text | References | PDF (4.2 MB) | EPUB
  • 158 Views
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Article
Loss of ARID1A promotes proliferation, migration and invasion via the Akt signaling pathway in NPC
Yang Yang, Xiaoyu Wang, Junjun Yang, Jingling Duan, Zhen Wu, Fan Yang, Xiaoling Zhang & Shengjun Xiao
Pages: 4931-4946
Published online: 29 May 2019
AbstractforLoss of ARID1A promotes proliferation, migration and invasion via the Akt signaling pathway in NPC | Full Text | References | PDF (6.6 MB) | EPUB
  • 127 Views
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Article
Nuclear GAPDH is vital for hypoxia-induced hepatic stellate cell apoptosis and is indicative of aggressive hepatocellular carcinoma behavior
Yihang Gong, Baojia Zou, Siqi Peng, Peiping Li, Genglong Zhu, Jiafan Chen, Jianxu Chen, Xialei Liu, Wenying Zhou, Lei Ding, Yutong Chen, Linjuan Zeng, Baimeng Zhang, Chaonong Cai & Jian Li
Pages: 4947-4956
Published online: 30 May 2019
AbstractforNuclear GAPDH is vital for hypoxia-induced hepatic stellate cell apoptosis and is indicative of aggressive hepatocellular carcinoma behavior | Full Text | References | PDF (2.5 MB) | EPUB
  • 92 Views
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Review

Review Article
Negative regulators of STAT3 signaling pathway in cancers
Moli Wu, Danyang Song, Hui Li, Yang Yang, Xiaodong Ma, Sa Deng, Changle Ren & Xiaohong Shu
Pages: 4957-4969
Published online: 29 May 2019
AbstractforNegative regulators of STAT3 signaling pathway in cancers | Full Text | References | PDF (954.6 KB) | EPUB
  • 145 Views
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Original Research

Article
Comprehensive analysis of genes based on chr1p/19q co-deletion reveals a robust 4-gene prognostic signature for lower grade glioma
Chuang Zhang, Ruoxi Yu, Zhi Li, Huicong Song, Dan Zang, Mingming Deng, Yibo Fan, Yunpeng Liu, Ye Zhang & Xiujuan Qu
Pages: 4971-4984
Published online: 29 May 2019
AbstractforComprehensive analysis of genes based on chr1p/19q co-deletion reveals a robust 4-gene prognostic signature for lower grade glioma | Full Text | References | PDF (5.1 MB) | EPUB
  • 68 Views
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Article
kshv-mir-k12-1-5p promotes cell growth and metastasis by targeting SOCS6 in Kaposi’s sarcoma cells
Jing Zhang, Xiong-Ming Pu & Yan Xiong
Pages: 4985-4995
Published online: 29 May 2019
Abstractforkshv-mir-k12-1-5p promotes cell growth and metastasis by targeting SOCS6 in Kaposi’s sarcoma cells | Full Text | References | PDF (2.8 MB) | EPUB
  • 59 Views
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Review

Review Article
Analyzing biological and molecular characteristics and genomic damage induced by exposure to asbestos
Diana Ospina, Victoria Eugenia Villegas, Giovanni Rodríguez-Leguizamón & Milena Rondón-Lagos
Pages: 4997-5012
Published online: 30 May 2019
AbstractforAnalyzing biological and molecular characteristics and genomic damage induced by exposure to asbestos | Full Text | References | PDF (2.6 MB) | EPUB
  • 177 Views
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Original Research

Article
Dosimetry comparison between a 3D printed minimally invasive guidance template and free implantation in the brachytherapy treatment of postoperative recurrent cervical carcinoma
Xiangkun Yuan, Yongxia Zhang, Mangmang Cui, Junjun Miao, Lei Gao, Jianwei Hu, Dandan Tian & Jinqiang You
Pages: 5013-5018
Published online: 30 May 2019
AbstractforDosimetry comparison between a 3D printed minimally invasive guidance template and free implantation in the brachytherapy treatment of postoperative recurrent cervical carcinoma | Full Text | References | PDF (594.4 KB) | EPUB
  • 78 Views
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Corrigendum

Correction
The efficacy and safety of apatinib in metastatic alveolar soft part sarcoma: a case series of six patients in one institution [Corrigendum]
Page: 5019
Published online: 31 May 2019
CitationforThe efficacy and safety of apatinib in metastatic alveolar soft part sarcoma: a case series of six patients in one institution [Corrigendum] | Full Text | PDF (145.6 KB) | EPUB
  • 48 Views
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Original Research

Article
Assessment of microRNA expression in leukemic cells as predictors of sensitivity to purine nucleoside analogs, fludarabine and cladribine, in chronic lymphocytic leukemia patients
Agnieszka Szymczyk, Sylwia Chocholska, Arkadiusz Macheta, Dariusz Szczepanek, Marek Hus & Monika Podhorecka
Pages: 5021-5031
Published online: 30 May 2019
AbstractforAssessment of microRNA expression in leukemic cells as predictors of sensitivity to purine nucleoside analogs, fludarabine and cladribine, in chronic lymphocytic leukemia patients | Full Text | References | PDF (829.3 KB) | EPUB
  • 60 Views
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Hypothesis

Plausibility of trophoblastic-like regulation of cancer tissue
Jean Piechowski
Pages: 5033-5046
Published online: 31 May 2019
AbstractforPlausibility of trophoblastic-like regulation of cancer tissue | Full Text | References | PDF (996.7 KB) | EPUB
  • 91 Views
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Original Research

Article
Mucin phenotype of differentiated early gastric cancer: an immunohistochemistry study supporting therapeutic decision making
Elisabetta Cavalcanti, Francesco De Michele, Giulio Lantone, Alba Panarese & Maria Lucia Caruso
Pages: 5047-5054
Published online: 17 Jun 2019
AbstractforMucin phenotype of differentiated early gastric cancer: an immunohistochemistry study supporting therapeutic decision making | Full Text | References | PDF (620.8 KB) | EPUB
  • 63 Views
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Article
Predictors of postoperative complications after robot-assisted radical cystectomy with extracorporeal urinary diversion
Chung Un Lee, Minyong Kang, Tae Jin Kim, Jun Phil Na, Hyun Hwan Sung, Hwang Gyun Jeon, Seong Il Seo, Seong Soo Jeon, Hyun Moo Lee & Byong Chang Jeong
Pages: 5055-5063
Published online: 31 May 2019
AbstractforPredictors of postoperative complications after robot-assisted radical cystectomy with extracorporeal urinary diversion | Full Text | References | PDF (240 KB) | EPUB
  • 84 Views
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Article
Definitive chemoradiotherapy and salvage chemotherapy for patients with isolated locoregional recurrence after radical resection of primary pancreatic cancer
Wei Shi, Rui Jiang, Fei Liang, Genhua Yu, Jiang Long & Jiandong Zhao
Pages: 5065-5073
Published online: 31 May 2019
AbstractforDefinitive chemoradiotherapy and salvage chemotherapy for patients with isolated locoregional recurrence after radical resection of primary pancreatic cancer | Full Text | References | PDF (400.8 KB) | EPUB
  • 57 Views
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Article
HMGB3 silence inhibits breast cancer cell proliferation and tumor growth by interacting with hypoxia-inducible factor 1α
Jun Gu, Tao Xu, Qin-Hua Huang, Chu-Miao Zhang & Hai-Yan Chen
Pages: 5075-5089
Published online: 31 May 2019
AbstractforHMGB3 silence inhibits breast cancer cell proliferation and tumor growth by interacting with hypoxia-inducible factor 1α | Full Text | References | PDF (4.4 MB) | EPUB
  • 96 Views
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Article
Serum hepatitis B viral (HBV) DNA is a predictive biomarker for survival in non-small cell lung cancer patients with chronic HBV infection
Yumei Fu, Xiaoyi Yang, Huifen Liang & Xingping Wu
Pages: 5091-5100
Published online: 31 May 2019
AbstractforSerum hepatitis B viral (HBV) DNA is a predictive biomarker for survival in non-small cell lung cancer patients with chronic HBV infection | Full Text | References | PDF (1.4 MB) | EPUB
  • 65 Views
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Article
Cancer prevalence among the rural poverty-stricken population in Northeast China
Baohua Liu, Xinxin Lao, Yang Feng, Jiazhuo Liu, Mingli Jiao, Miaomiao Zhao, Jiahui Wang, Xin Zhang, Jingjing Liu, Xinye Qi, Huan Liu, Ruohui Chen, Qunhong Wu & Yanhua Hao
Pages: 5101-5112
Published online: 31 May 2019
AbstractforCancer prevalence among the rural poverty-stricken population in Northeast China | Full Text | References | PDF (1.4 MB) | EPUB
  • 104 Views
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Article
Association of caveolin-1 protein expression with hepatocellular carcinoma: a meta-analysis and literature review
Yan Zhang, Wenjuan Fan, Jiang Wu, Jinglong Dong & Zhanjun Cui
Pages: 5113-5122
Published online: 31 May 2019
AbstractforAssociation of caveolin-1 protein expression with hepatocellular carcinoma: a meta-analysis and literature review | Full Text | References | PDF (1.9 MB) | EPUB
  • 54 Views
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Corrigendum

Correction
Immune inflammation indicators in anal cancer patients treated with concurrent chemoradiation: training and validation cohort with online calculator (ARC: Anal Cancer Response Classifier) [Corrigendum]
Page: 5123
Published online: 25 Jun 2019
CitationforImmune inflammation indicators in anal cancer patients treated with concurrent chemoradiation: training and validation cohort with online calculator (ARC: Anal Cancer Response Classifier) [Corrigendum] | Full Text | PDF (151.7 KB) | EPUB
  • 52 Views
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Original Research

Article
Combination of the preoperative albumin to globulin ratio and neutrophil to lymphocyte ratio as a novel prognostic factor in patients with triple negative breast cancer
Qijia Xuan, Yan Yang, Hongfei Ji, Shuli Tang, Juan Zhao, Jiayue Shao & Jingxuan Wang
Pages: 5125-5131
Published online: 31 May 2019
AbstractforCombination of the preoperative albumin to globulin ratio and neutrophil to lymphocyte ratio as a novel prognostic factor in patients with triple negative breast cancer | Full Text | References | PDF (594.5 KB) | EPUB
  • 73 Views
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Article
Connexin 32 downregulation is critical for chemoresistance in oxaliplatin-resistant HCC cells associated with EMT
Yan Yang, Jing-Hao Yao, Qian-Yu Du, Yong-Chun Zhou, Ting-Jing Yao, Qiong Wu, Jing Liu & Yu-Rong Ou
Pages: 5133-5146
Published online: 31 May 2019
AbstractforConnexin 32 downregulation is critical for chemoresistance in oxaliplatin-resistant HCC cells associated with EMT | Full Text | References | PDF (4.9 MB) | EPUB
  • 66 Views
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Article
NETO2 promotes pancreatic cancer cell proliferation, invasion and migration via activation of the STAT3 signaling pathway
Yaxiong Li, Yongping Zhang & Jiansheng Liu
Pages: 5147-5156
Published online: 06 Jun 2019
AbstractforNETO2 promotes pancreatic cancer cell proliferation, invasion and migration via activation of the STAT3 signaling pathway | Full Text | References | PDF (3.9 MB) | EPUB
  • 81 Views
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Article
Preoperative neutrophil–lymphocyte and platelet–lymphocyte ratios as independent predictors of T stages in hilar cholangiocarcinoma
Hanchun Huang, Xueshuai Wan, Yi Bai, Jin Bian, Jianping Xiong, Yiyao Xu, Xinting Sang & Haitao Zhao
Pages: 5157-5162
Published online: 04 Jun 2019
AbstractforPreoperative neutrophil–lymphocyte and platelet–lymphocyte ratios as independent predictors of T stages in hilar cholangiocarcinoma | Full Text | References | PDF (410.6 KB) | EPUB
  • 58 Views
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Article
c-MYC expression in T (III/IV) stage oral squamous cell carcinoma (OSCC) patients
Shu-Hui Lin, Hsin-Kai Wang, Kun-Tu Yeh, Hui-Chun Tai, Hui-Yi Wang, Lan-Ru Huang, Chun-Wen Chiu, Chia-Min Chung & Bharath Kumar Velmurugan
Pages: 5163-5169
Published online: 05 Jun 2019
Abstractforc-MYC expression in T (III/IV) stage oral squamous cell carcinoma (OSCC) patients | Full Text | References | PDF (611.1 KB) | EPUB
  • 110 Views
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Article
Neutrophils infiltration and its correlation with human papillomavirus status in the oral squamous cell carcinoma
Chen Li, Lei Zhao, Qingjie Wang, Shao Ma, Jintang Sun, Chao Ma, Jia Liu, Xuanxuan Jing, Dan Ai, Zhaodi Nan & Xun Qu
Pages: 5171-5185
Published online: 05 Jun 2019
AbstractforNeutrophils infiltration and its correlation with human papillomavirus status in the oral squamous cell carcinoma | Full Text | References | PDF (2.4 MB) | EPUB
  • 90 Views
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Article
Development and validation of a prognostic score predicting recurrence in resected combined hepatocellular cholangiocarcinoma
Meng-Xin Tian, Liu-Ping Luo, Wei-Ren Liu, Wei Deng, Jia-Cheng Yin, Lei Jin, Xi-Fei Jiang, Yu-Fu Zhou, Wei-Feng Qu, Zheng Tang, Han Wang, Chen-Yang Tao, Yuan Fang, Shuang-Jian Qiu, Jian Zhou, Jing-Feng Liu, Jia Fan & Ying-Hong Shi
Pages: 5187-5195
Published online: 05 Jun 2019
AbstractforDevelopment and validation of a prognostic score predicting recurrence in resected combined hepatocellular cholangiocarcinoma | Full Text | References | PDF (883.3 KB) | EPUB
  • 78 Views
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Article
The molecular mechanisms underlying BCR/ABL degradation in chronic myeloid leukemia cells promoted by Beclin1-mediated autophagy
Xianbo Huang, Ying Li, Lihong Shou, Li Li, Zhenzhen Chen, Xiujin Ye & Wenbin Qian
Pages: 5197-5208
Published online: 06 Jun 2019
AbstractforThe molecular mechanisms underlying BCR/ABL degradation in chronic myeloid leukemia cells promoted by Beclin1-mediated autophagy | Full Text | References | PDF (3.9 MB) | EPUB
  • 99 Views
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Article
Identification of hub genes and key pathways associated with angioimmunoblastic T-cell lymphoma using weighted gene co-expression network analysis
Xiaoqian Li, Zijian Liu, Mi Mi, Caijiao Zhang, Yin Xiao, Xinxiu Liu, Gang Wu & Liling Zhang
Pages: 5209-5220
Published online: 06 Jun 2019
AbstractforIdentification of hub genes and key pathways associated with angioimmunoblastic T-cell lymphoma using weighted gene co-expression network analysis | Full Text | References | PDF (5.2 MB) | EPUB
  • 122 Views
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Article
Definitive radiotherapy or chemoradiotherapy for distal rectal cancer with early stage of cT1-2N0
Hai-Hua Peng, Zhi-Wei Liao, Xiao-Dan Lin, Xing-Sheng Qiu & Kai-Yun You
Pages: 5221-5229
Published online: 10 Jun 2019
AbstractforDefinitive radiotherapy or chemoradiotherapy for distal rectal cancer with early stage of cT1-2N0 | Full Text | References | PDF (409.7 KB) | EPUB
  • 72 Views
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Article
RETRACTED ARTICLE: Tangeretin inhibits hepatocellular carcinoma proliferation and migration by promoting autophagy-related BECLIN1
Jiao Zheng, Yaqin Shao, Yu Jiang, Fang Chen, Sulai Liu, Nanhui Yu, Dandan Zhang, Xiehong Liu & Lianhong Zou
Pages: 5231-5242
Published online: 06 Jun 2019
AbstractforRETRACTED ARTICLE: Tangeretin inhibits hepatocellular carcinoma proliferation and migration by promoting autophagy-related BECLIN1 | PDF (4.6 MB)
  • 55 Views
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Article
ELF-1 expression in nasopharyngeal carcinoma facilitates proliferation and metastasis of cancer cells via modulation of CCL2/CCR2 signaling
Chang-Han Chen, Li-Jen Su, Hsin-Ting Tsai & Chung-Feng Hwang
Pages: 5243-5254
Published online: 06 Jun 2019
AbstractforELF-1 expression in nasopharyngeal carcinoma facilitates proliferation and metastasis of cancer cells via modulation of CCL2/CCR2 signaling | Full Text | References | PDF (3.7 MB) | EPUB
  • 75 Views
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Article
RETRACTED ARTICLE: MicroRNA-876 is sponged by long noncoding RNA LINC00707 and directly targets metadherin to inhibit breast cancer malignancy
Tong Li, Yunpeng Li & Hongyan Sun
Pages: 5255-5269
Published online: 06 Jun 2019
AbstractforRETRACTED ARTICLE: MicroRNA-876 is sponged by long noncoding RNA LINC00707 and directly targets metadherin to inhibit breast cancer malignancy | PDF (4.6 MB)
  • 18 Views
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Review

Review Article
Current status of liquid biopsies for the detection and management of prostate cancer
Yi-Tsung Lu, Kevin Delijani, Andrew Mecum & Amir Goldkorn
Pages: 5271-5291
Published online: 06 Jun 2019
AbstractforCurrent status of liquid biopsies for the detection and management of prostate cancer | Full Text | References | PDF (1.1 MB) | EPUB
  • 220 Views
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Original Research

Article
Safety and efficacy of combination therapy with apatinib and doxorubicin in metastatic soft tissue sarcomas: an observational study from multiple institutions
Zhichao Tian, Xin Wang, Zhiyong Liu, Jiaqiang Wang, Weitao Yao, Yao Zhao, Songtao Gao, Peng Zhang & Hong Ge
Pages: 5293-5300
Published online: 06 Jun 2019
AbstractforSafety and efficacy of combination therapy with apatinib and doxorubicin in metastatic soft tissue sarcomas: an observational study from multiple institutions | Full Text | References | PDF (839.2 KB) | EPUB
  • 97 Views
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Article
An integrated prediction model of recurrence in endometrial endometrioid cancers
Marina D Miller, Erin A Salinas, Andreea M Newtson, Deepti Sharma, Matthew E Keeney, Akshaya Warrier, Brian J Smith, David P Bender, Michael J Goodheart, Kristina W Thiel, Eric J Devor, Kimberly K Leslie & Jesus Gonzalez-Bosquet
Pages: 5301-5315
Published online: 06 Jun 2019
AbstractforAn integrated prediction model of recurrence in endometrial endometrioid cancers | Full Text | References | PDF (1.2 MB) | EPUB
  • 183 Views
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Article
miR-6716-5p promotes metastasis of colorectal cancer through downregulating NAT10 expression
Zhenzhen Liu, Xiaofeng Liu, Yuan Li, Pengwei Ren, Chunfeng Zhang, Lijun Wang, Xiaojuan Du & Baocai Xing
Pages: 5317-5332
Published online: 06 Jun 2019
AbstractformiR-6716-5p promotes metastasis of colorectal cancer through downregulating NAT10 expression | Full Text | References | PDF (4.6 MB) | EPUB
  • 72 Views
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Article
Gephyrin suppresses lung squamous cell carcinoma development by reducing mTOR pathway activation
Xiang Zhang, Dezhi Cheng, Yu Liu, Yuanbo Wu & Zhifeng He
Pages: 5333-5341
Published online: 07 Jun 2019
AbstractforGephyrin suppresses lung squamous cell carcinoma development by reducing mTOR pathway activation | Full Text | References | PDF (1.8 MB) | EPUB
  • 62 Views
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Article
Urinary 8-hydroxydeoxyguanosine in relation to XRCC1 rs25487 G/A (Arg399Gln) and OGG1 rs1052133 C/G (Ser326Cys) DNA repair genes polymorphisms in patients with chronic hepatitis C and related hepatocellular carcinoma
Aida A Mahmoud, Mohammed H Hassan, Ali A Ghweil, Amany Abdelrahman, Asmaa N Mohammad & Hesham H Ameen
Pages: 5343-5351
Published online: 10 Jun 2019
AbstractforUrinary 8-hydroxydeoxyguanosine in relation to XRCC1 rs25487 G/A (Arg399Gln) and OGG1 rs1052133 C/G (Ser326Cys) DNA repair genes polymorphisms in patients with chronic hepatitis C and related hepatocellular carcinoma | Full Text | References | PDF (1 MB) | EPUB
  • 132 Views
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Article
MicroRNA-193a-3p suppresses the colorectal cancer cell proliferation and progression through downregulating the PLAU expression
Maosong Lin, Zan Zhang, Mingjun Gao, Hong Yu, Haihui Sheng & Junxing Huang
Pages: 5353-5363
Published online: 12 Jun 2019
AbstractforMicroRNA-193a-3p suppresses the colorectal cancer cell proliferation and progression through downregulating the PLAU expression | Full Text | References | PDF (3.1 MB) | EPUB
  • 99 Views
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Article
Prognostic value of pretreatment neutrophil count in metastatic renal cell carcinoma: a systematic review and meta-analysis
Jie Shen, Zhen Chen, Min Fan, Hao Lu, Qianfeng Zhuang & Xiaozhou He
Pages: 5365-5374
Published online: 10 Jun 2019
AbstractforPrognostic value of pretreatment neutrophil count in metastatic renal cell carcinoma: a systematic review and meta-analysis | Full Text | References | PDF (1.5 MB) | EPUB
  • 56 Views
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Article
The novel lncRNA p4516 acts as a prognostic biomarker promoting gastric cancer cell proliferation and metastasis
Meng-Lin Nie, Jing Han, Han-Chen Huang, Ting Guo, Long-Tao Huangfu, Xiao-Jing Cheng, Xiao-Mei Li, Hong Du, Qing-Da Li, Xian-Zi Wen & Jia-Fu Ji
Pages: 5375-5391
Published online: 12 Jun 2019
AbstractforThe novel lncRNA p4516 acts as a prognostic biomarker promoting gastric cancer cell proliferation and metastasis | Full Text | References | PDF (4.4 MB) | EPUB
  • 65 Views
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Article
Genetic polymorphisms in IL-7 and IL-7R are correlated with lung cancer risk in the Chinese Han population
Chan Zhang, Pincan Su, Wanlu Chen, Qi Li, Run Dai, YuJing Cheng & Jiangcun Yang
Pages: 5393-5401
Published online: 11 Jun 2019
AbstractforGenetic polymorphisms in IL-7 and IL-7R are correlated with lung cancer risk in the Chinese Han population | Full Text | References | PDF (422.5 KB) | EPUB
  • 62 Views
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Article
Exercise during adjuvant treatment for colorectal cancer: treatment completion, treatment-related toxicities, body composition, and serum level of adipokines
Yoo Jin Shim, Hong Jun Kim, Sang Cheul Oh, Sun Il Lee & Seung Wook Choi
Pages: 5403-5412
Published online: 11 Jun 2019
AbstractforExercise during adjuvant treatment for colorectal cancer: treatment completion, treatment-related toxicities, body composition, and serum level of adipokines | Full Text | References | PDF (1.3 MB) | EPUB
  • 123 Views
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Article
CircRNA hsa_circ_0004585 as a potential biomarker for colorectal cancer
Jinhai Tian, Xianghong Xi, Jia Wang, Jingjing Yu, Qi Huang, Rong Ma, Xu Zhang, Hai Li & Libin Wang
Pages: 5413-5423
Published online: 11 Jun 2019
AbstractforCircRNA hsa_circ_0004585 as a potential biomarker for colorectal cancer | Full Text | References | PDF (2.5 MB) | EPUB
  • 216 Views
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Article
Bioinformatics analysis of dysregulated microRNAs in exosomes from docetaxel-resistant and parental human breast cancer cells
Wei-Xian Chen, Ling-Yun Xu, Lin Cheng, Qi Qian, Xiao He, Wen-Ting Peng & Yu-Lan Zhu
Pages: 5425-5435
Published online: 12 Jun 2019
AbstractforBioinformatics analysis of dysregulated microRNAs in exosomes from docetaxel-resistant and parental human breast cancer cells | Full Text | References | PDF (4.8 MB) | EPUB
  • 101 Views
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Article
MicroRNA-371-3 cluster as biomarkers for the diagnosis and prognosis of cancers
Bei Pan, Bangshun He, Xueni Xu, Xiangxiang Liu, Tao Xu, Mu Xu, Xiaoxiang Chen, Kaixuan Zeng, Kang Lin, Xiuxiu Hu, Li Sun, Yuqin Pan, Huiling Sun & Shukui Wang
Pages: 5437-5457
Published online: 13 Jun 2019
AbstractforMicroRNA-371-3 cluster as biomarkers for the diagnosis and prognosis of cancers | Full Text | References | PDF (4.1 MB) | EPUB
  • 73 Views
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Article
IGF1R facilitates epithelial-mesenchymal transition and cancer stem cell properties in neuroblastoma via the STAT3/AKT axis
Xiao-Hui Wang, Hai-Ying Wu, Jian Gao, Xu-Hui Wang, Tian-Hui Gao & Shu-Feng Zhang
Pages: 5459-5472
Published online: 12 Jun 2019
AbstractforIGF1R facilitates epithelial-mesenchymal transition and cancer stem cell properties in neuroblastoma via the STAT3/AKT axis | Full Text | References | PDF (4.1 MB) | EPUB
  • 119 Views
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Article
Prognostic value of the 2018 FIGO staging system for cervical cancer patients with surgical risk factors
Ding-Ding Yan, Qiu Tang, Jian-Hong Chen, Ye-Qiang Tu & Xiao-Juan Lv
Pages: 5473-5480
Published online: 13 Jun 2019
AbstractforPrognostic value of the 2018 FIGO staging system for cervical cancer patients with surgical risk factors | Full Text | References | PDF (395 KB) | EPUB
  • 130 Views
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Article
Vascular index measured by smart 3-D superb microvascular imaging can help to differentiate malignant and benign breast lesion
Xiao-Yan Zhang, Li Zhang, Na Li, Qing-Li Zhu, Jian-Chu Li, Qiang Sun, Hong-Yan Wang & Yu-Xin Jiang
Pages: 5481-5487
Published online: 13 Jun 2019
AbstractforVascular index measured by smart 3-D superb microvascular imaging can help to differentiate malignant and benign breast lesion | Full Text | References | PDF (1.4 MB) | EPUB
  • 116 Views
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Article
Clinical genetic features and related survival implications in patients with surgically resected large-cell lung cancer
Fang Wang, Jia-Bin Lu, Xiao-Yan Wu, Yan-Fen Feng, Qiong Shao, Xin An & Hai-Yun Wang
Pages: 5489-5499
Published online: 14 Jun 2019
AbstractforClinical genetic features and related survival implications in patients with surgically resected large-cell lung cancer | Full Text | References | PDF (3.4 MB) | EPUB
  • 57 Views
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Article
MAT2B expression correlates with poor prognosis in triple-negative breast cancer
Jin Xu, Di Wu, Siliang Wang & Zhe Wang
Pages: 5501-5511
Published online: 14 Jun 2019
AbstractforMAT2B expression correlates with poor prognosis in triple-negative breast cancer | Full Text | References | PDF (2.2 MB) | EPUB
  • 69 Views
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Article
Effects of anesthetic technique and surgery on myeloid-derived suppressor cells and prognosis in women who underwent breast cancer surgery: a prospective study
Tao Yan, Guo-Hua Zhang, Yao-Zhong Cheng, Lin-Xin Wu, Xiao-Yan Liu, Yu-Lin Sun, Hui Zheng & Li Sun
Pages: 5513-5522
Published online: 18 Jun 2019
AbstractforEffects of anesthetic technique and surgery on myeloid-derived suppressor cells and prognosis in women who underwent breast cancer surgery: a prospective study | Full Text | References | PDF (1.8 MB) | EPUB
  • 84 Views
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Article
Determination of portal vein tumor thrombus blood supply using in vivo cellular magnetic resonance imaging in a rabbit model
Xiuming Zhang, Bei Wu, Zhen Guo, Yang Gao, Wei Xi, Hui Yu, Guodong Feng, Jingyuan Zhang, Wenrong Shen & Jun Chen
Pages: 5523-5529
Published online: 18 Jun 2019
AbstractforDetermination of portal vein tumor thrombus blood supply using in vivo cellular magnetic resonance imaging in a rabbit model | Full Text | References | PDF (1.5 MB) | EPUB
  • 71 Views
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Article
Distribution of circulating tumor cell phenotype in early cervical cancer
Li Pan, Gaoshu Yan, Wenli Chen, Lei Sun, Jichuan Wang & Jialin Yang
Pages: 5531-5536
Published online: 17 Jun 2019
AbstractforDistribution of circulating tumor cell phenotype in early cervical cancer | Full Text | References | PDF (630.2 KB) | EPUB
  • 111 Views
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Article
Lipids in surgical aerosol as diagnosis biomarkers for discrimination of lung cancer
Jianyong Zhang, Qiaoling Zheng, Wenxiong Zhang, Nanpeng Wang, Jianjun Xu, Xiaoshu Cheng & Yiping Wei
Pages: 5537-5543
Published online: 17 Jun 2019
AbstractforLipids in surgical aerosol as diagnosis biomarkers for discrimination of lung cancer | Full Text | References | PDF (1.1 MB) | EPUB
  • 73 Views
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Article
Sinonasal/nasopharyngeal pleomorphic adenoma and carcinoma ex pleomorphic adenoma: a report of 17 surgical cases combined with a literature review
Wanpeng Li, Hanyu Lu, Huankang Zhang, Yuting Lai, Jia Zhang, Yang Ni & Dehui Wang
Pages: 5545-5555
Published online: 17 Jun 2019
AbstractforSinonasal/nasopharyngeal pleomorphic adenoma and carcinoma ex pleomorphic adenoma: a report of 17 surgical cases combined with a literature review | Full Text | References | PDF (5.1 MB) | EPUB
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Article
Candidate tumor suppressor gene IRF6 is involved in human breast cancer pathogenesis via modulating PI3K-regulatory subunit PIK3R2 expression
Hong-Fa Xu, Tie-Jun Huang, Qin Yang, Liang Xu, Fen Lin, Yan-Hong Lang, Hao Hu, Li-Xia Peng, Dong-Fang Meng, Yu-Jie Xie, Li Tan, Chao-Nan Qian & Bi-Jun Huang
Pages: 5557-5572
Published online: 21 Jun 2019
Abstractfor Candidate tumor suppressor gene IRF6 is involved in human breast cancer pathogenesis via modulating PI3K-regulatory subunit PIK3R2 expression | Full Text | References | PDF (3.8 MB) | EPUB
  • 105 Views
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Article
miR-1-3p suppresses the epithelial-mesenchymal transition property in renal cell cancer by downregulating Fibronectin 1
Jianghui Liu, Yingxiong Huang, Quanyong Cheng, Jifei Wang, Jidong Zuo, Ying Liang & Gang Yuan
Pages: 5573-5587
Published online: 21 Jun 2019
AbstractformiR-1-3p suppresses the epithelial-mesenchymal transition property in renal cell cancer by downregulating Fibronectin 1 | Full Text | References | PDF (3.8 MB) | EPUB
  • 88 Views
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Article
SNHG1 contributes to proliferation and invasion by regulating miR-382 in breast cancer
Shipeng Zheng, Mengquan Li, Keke Miao & Han Xu
Pages: 5589-5598
Published online: 18 Jun 2019
AbstractforSNHG1 contributes to proliferation and invasion by regulating miR-382 in breast cancer | Full Text | References | PDF (2 MB) | EPUB
  • 89 Views
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Article
Early or deferred treatment of smoldering multiple myeloma: a meta-analysis on randomized controlled studies
Ai-Lin Zhao, Kai-Ni Shen, Ji-Nuo Wang, Lan-Qing Huo, Jian Li & Xin-Xin Cao
Pages: 5599-5611
Published online: 21 Jun 2019
AbstractforEarly or deferred treatment of smoldering multiple myeloma: a meta-analysis on randomized controlled studies | Full Text | References | PDF (3.5 MB) | EPUB
  • 127 Views
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Article
Systemic inflammation score: a novel risk stratification tool for postoperative outcomes after video-assisted thoracoscopic surgery lobectomy for early-stage non-small-cell lung cancer
Shuangjiang Li, Zhiqiang Wang, Wenbiao Zhang, Jue Li, Kun Zhou & Guowei Che
Pages: 5613-5628
Published online: 21 Jun 2019
AbstractforSystemic inflammation score: a novel risk stratification tool for postoperative outcomes after video-assisted thoracoscopic surgery lobectomy for early-stage non-small-cell lung cancer | Full Text | References | PDF (872.6 KB) | EPUB
  • 79 Views
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Review

Review Article
Prognostic value of long non-coding RNA CRNDE in gastrointestinal cancers: a meta-analysis
Tian-Yu He, Si-Han Li, Jin Huang, Ming Gong & Guang Li
Pages: 5629-5642
Published online: 21 Jun 2019
AbstractforPrognostic value of long non-coding RNA CRNDE in gastrointestinal cancers: a meta-analysis | Full Text | References | PDF (3.1 MB) | EPUB
  • 66 Views
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Original Research

Article
Serum pepsinogen assay is not recommended for the diagnosis of esophageal squamous cell carcinoma: a systematic review and meta-analysis
Xiao-Bo Liu, Zi-Ye Gao, Qing-Hui Zhang, Shu Jin, Bo Gao, Gong-Li Yang & Sheng-Bao Li
Pages: 5643-5654
Published online: 27 Jun 2019
AbstractforSerum pepsinogen assay is not recommended for the diagnosis of esophageal squamous cell carcinoma: a systematic review and meta-analysis | Full Text | References | PDF (3 MB) | EPUB
  • 53 Views
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Article
Statin use and its potential therapeutic role in esophageal cancer: a systematic review and meta-analysis
Cen Zhou, Xi Zhong, Peng Gao, Zhonghua Wu, Jinxin Shi, Zhexu Guo, Zhenning Wang & Yongxi Song
Pages: 5655-5663
Published online: 19 Jun 2019
AbstractforStatin use and its potential therapeutic role in esophageal cancer: a systematic review and meta-analysis | Full Text | References | PDF (984.6 KB) | EPUB
  • 92 Views
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Article
Concurrent TP53 mutations predict poor outcomes of EGFR-TKI treatments in Chinese patients with advanced NSCLC
Helei Hou, Kang Qin, Yu Liang, Chuantao Zhang, Dong Liu, Haiping Jiang, Kewei Liu, Jingjuan Zhu, Hongying Lv, Tianjun Li & Xiaochun Zhang
Pages: 5665-5675
Published online: 21 Jun 2019
AbstractforConcurrent TP53 mutations predict poor outcomes of EGFR-TKI treatments in Chinese patients with advanced NSCLC | Full Text | References | PDF (733.9 KB) | EPUB
  • 172 Views
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Article
Conversion of immunohistochemical markers and breast density are associated with pathological response and prognosis in very young breast cancer patients who fail to achieve a pathological complete response after neoadjuvant chemotherapy
Yue Zhao, Xiaolei Wang, Yuanxi Huang, Xianli Zhou & Dongwei Zhang
Pages: 5677-5690
Published online: 20 Jun 2019
AbstractforConversion of immunohistochemical markers and breast density are associated with pathological response and prognosis in very young breast cancer patients who fail to achieve a pathological complete response after neoadjuvant chemotherapy | Full Text | References | PDF (3.9 MB) | EPUB
  • 87 Views
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Article
RETRACTED ARTICLE: Long noncoding RNA LINC00511 promotes cell growth and invasion in triple-negative breast cancer by interacting with Snail
Ruilei Liu, Liang Wang, Tianyu Gan, Tao Pan, Jianglong Huang & Mingjun Bai
Pages: 5691-5699
Published online: 24 Jun 2019
AbstractforRETRACTED ARTICLE: Long noncoding RNA LINC00511 promotes cell growth and invasion in triple-negative breast cancer by interacting with Snail | PDF (1.4 MB)
  • 10 Views
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Open Access
Article
Construction and validation of a seven-microRNA signature as a prognostic tool for lung squamous cell carcinoma
Zuhuan Gan, Qiyun Zou, Yan Lin, Xiaoyuan Huang, Zhong Huang, Zhichao Chen, Zihai Xu & Yufeng Lv
Pages: 5701-5709
Published online: 21 Jun 2019
AbstractforConstruction and validation of a seven-microRNA signature as a prognostic tool for lung squamous cell carcinoma | Full Text | References | PDF (1.9 MB) | EPUB
  • 78 Views
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Review

Review Article
Laparoscopic hepatectomy versus radiofrequency ablation for hepatocellular carcinoma: a systematic review and meta-analysis
Xiaocheng Li, Yu-Shen Wu, Duke Chen & Huapeng Lin
Pages: 5711-5724
Published online: 24 Jun 2019
AbstractforLaparoscopic hepatectomy versus radiofrequency ablation for hepatocellular carcinoma: a systematic review and meta-analysis | Full Text | References | PDF (4.6 MB) | EPUB
  • 69 Views
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Original Research

Article
TRIM14 promotes cell proliferation and inhibits apoptosis by suppressing PTEN in colorectal cancer
Weidong Shen, Zhonghai Jin, Xiuping Tong, Haiying Wang, Lilei Zhuang, Xiaofeng Lu & Shenbao Wu
Pages: 5725-5735
Published online: 24 Jun 2019
AbstractforTRIM14 promotes cell proliferation and inhibits apoptosis by suppressing PTEN in colorectal cancer | Full Text | References | PDF (3.3 MB) | EPUB
  • 94 Views
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Article
Cancer-associated fibroblasts endow stem-like qualities to liver cancer cells by modulating autophagy
Zhenxiong Zhao, Shuya Bai, Ronghua Wang, Si Xiong, Yawen Li, Xiju Wang, Wei Chen & Bin Cheng
Pages: 5737-5744
Published online: 24 Jun 2019
AbstractforCancer-associated fibroblasts endow stem-like qualities to liver cancer cells by modulating autophagy | Full Text | References | PDF (1.8 MB) | EPUB
  • 114 Views
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Article
Detection of a novel panel of somatic mutations in plasma cell-free DNA and its diagnostic value in hepatocellular carcinoma
Yu Xiong, Cheng-Rong Xie, Sheng Zhang, Jin Chen & Zhen-Yu Yin
Pages: 5745-5756
Published online: 28 Jun 2019
AbstractforDetection of a novel panel of somatic mutations in plasma cell-free DNA and its diagnostic value in hepatocellular carcinoma | Full Text | References | PDF (2.7 MB) | EPUB
  • 100 Views
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Article
Safety and efficacy of amrubicin monotherapy in patients with platinum-refractory metastatic neuroendocrine carcinoma of the gastrointestinal tract: a single cancer center retrospective study
Yusuke Kitagawa, Hiroki Osumi, Eiji Shinozaki, Yumiko Ota, Izuma Nakayama, Takeshi Suzuki, Takeru Wakatsuki, Takashi Ichimura, Mariko Ogura, Akira Ooki, Daisuke Takahari, Mitsukuni Suenaga, Keisho Chin & Kensei Yamaguchi
Pages: 5757-5764
Published online: 25 Jun 2019
AbstractforSafety and efficacy of amrubicin monotherapy in patients with platinum-refractory metastatic neuroendocrine carcinoma of the gastrointestinal tract: a single cancer center retrospective study | Full Text | References | PDF (280.3 KB) | EPUB
  • 53 Views
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Review

Review Article
The prognosis comparison of different molecular subtypes of breast tumors after radiotherapy and the intrinsic reasons for their distinct radiosensitivity
Lin He, Yang Lv, Yuhua Song & Biyuan Zhang
Pages: 5765-5775
Published online: 28 Jun 2019
Abstractfor The prognosis comparison of different molecular subtypes of breast tumors after radiotherapy and the intrinsic reasons for their distinct radiosensitivity | Full Text | References | PDF (1 MB) | EPUB
  • 153 Views
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Original Research

Article
Prognostic significance of a novel indicator (PSApostd3/PSApre) for PSA recurrence in patients after radical prostatectomy
Zhien Zhou, Yinyan Xu, Qianyue Li, Weigang Yan, Yi Zhou, Zhibo Zheng, Hanzhong Li & Zhigang Ji
Pages: 5777-5783
Published online: 25 Jun 2019
AbstractforPrognostic significance of a novel indicator (PSApostd3/PSApre) for PSA recurrence in patients after radical prostatectomy | Full Text | References | PDF (593.5 KB) | EPUB
  • 49 Views
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Article
Genome-wide DNA methylation and RNA expression profiles identified RIPK3 as a differentially methylated gene in Chlamydia pneumoniae infection lung carcinoma patients in China
Wei-Min Xiong, Qiu-Ping Xu, Ren-Dong Xiao, Zhi-Jian Hu, Lin Cai & Fei He
Pages: 5785-5797
Published online: 28 Jun 2019
AbstractforGenome-wide DNA methylation and RNA expression profiles identified RIPK3 as a differentially methylated gene in Chlamydia pneumoniae infection lung carcinoma patients in China | Full Text | References | PDF (2.1 MB) | EPUB
  • 82 Views
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Article
siPRDX2-elevated DNM3 inhibits the proliferation and metastasis of colon cancer cells via AKT signaling pathway
Yini Ma, Liying Guan, Yanxin Han, Yi Zhou, Xiaoming Li, Yumei Liu, Xiujuan Zhang, Weiying Zhang, Xiaohong Li, Shuhua Wang & Weidong Lu
Pages: 5799-5811
Published online: 28 Jun 2019
AbstractforsiPRDX2-elevated DNM3 inhibits the proliferation and metastasis of colon cancer cells via AKT signaling pathway | Full Text | References | PDF (3.7 MB) | EPUB
  • 57 Views
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Article
Familial association of lung cancer with liver cancer in first-degree relatives
Chong-Rui Xu, Huan Lin, Jian Su, Xu-Chao Zhang, Yi-Sheng Huang, Xue-Ning Yang, Qing Zhou, Jin-Ji Yang, Wen-Zhao Zhong & Yi-Long Wu
Pages: 5813-5819
Published online: 28 Jun 2019
AbstractforFamilial association of lung cancer with liver cancer in first-degree relatives | Full Text | References | PDF (240.6 KB) | EPUB
  • 75 Views
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Article
RETRACTED ARTICLE: microRNA-548b suppresses aggressive phenotypes of hepatocellular carcinoma by directly targeting high-mobility group box 1 mRNA
Zhennan Yun, Fanqi Meng, Peiqiang Jiang, Meng Yue & Shiquan Li
Pages: 5821-5834
Published online: 25 Jun 2019
AbstractforRETRACTED ARTICLE: microRNA-548b suppresses aggressive phenotypes of hepatocellular carcinoma by directly targeting high-mobility group box 1 mRNA | PDF (3.9 MB)
  • 11 Views
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Article
Sp1 contributes to radioresistance of cervical cancer through targeting G2/M cell cycle checkpoint CDK1
Yuan-Run Deng, Xiao-Jing Chen, Wei Chen, Lan-Fang Wu, Hui-Ping Jiang, Dan Lin, Li-Jing Wang, Wei Wang & Sui-Qun Guo
Pages: 5835-5844
Published online: 28 Jun 2019
AbstractforSp1 contributes to radioresistance of cervical cancer through targeting G2/M cell cycle checkpoint CDK1 | Full Text | References | PDF (1.9 MB) | EPUB
  • 105 Views
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Article
MicroRNA-3662 targets ZEB1 and attenuates the invasion of the highly aggressive melanoma cell line A375
Lin Zhu, Zhifei Liu, Ruijia Dong, Xiaojun Wang, Mingzi Zhang, Xiao Guo, Nanze Yu & Ang Zeng
Pages: 5845-5856
Published online: 28 Jun 2019
AbstractforMicroRNA-3662 targets ZEB1 and attenuates the invasion of the highly aggressive melanoma cell line A375 | Full Text | References | PDF (2.4 MB) | EPUB
  • 101 Views
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Article
Evaluation of therapeutic efficacy with CytoSorter® circulating tumor cell–capture system in patients with locally advanced head and neck squamous cell carcinoma
Weihui Zheng, Yibiao Zhang, Liang Guo, Shengye Wang, Meiyu Fang, Weimin Mao & Jianlin Lou
Pages: 5857-5869
Published online: 27 Jun 2019
AbstractforEvaluation of therapeutic efficacy with CytoSorter® circulating tumor cell–capture system in patients with locally advanced head and neck squamous cell carcinoma | Full Text | References | PDF (1.4 MB) | EPUB
  • 93 Views
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Article
ZNF488 is an independent prognostic indicator in nasopharyngeal carcinoma and promotes cell adhesion and proliferation via collagen IV/FAK/AKT/Cyclin D1 pathway
Dan Zong, Ning Jiang, Jian-Hua Xu, De-Jun Wang, Huan-Feng Zhu, Li-Rong Wu, Cheng Chen, Li Yin & Xia He
Pages: 5871-5882
Published online: 28 Jun 2019
AbstractforZNF488 is an independent prognostic indicator in nasopharyngeal carcinoma and promotes cell adhesion and proliferation via collagen IV/FAK/AKT/Cyclin D1 pathway | Full Text | References | PDF (3.5 MB) | EPUB
  • 61 Views
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Article
Atractylon induces apoptosis and suppresses metastasis in hepatic cancer cells and inhibits growth in vivo
Yang Cheng, Tianyang Chen, Xueli Yang, Jianhua Xue & Jianjie Chen
Pages: 5883-5894
Published online: 28 Jun 2019
AbstractforAtractylon induces apoptosis and suppresses metastasis in hepatic cancer cells and inhibits growth in vivo | Full Text | References | PDF (4.2 MB) | EPUB
  • 103 Views
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Review

Review Article
The emerging roles of PIWI-interacting RNA in human cancers
Yaya Yu, Jing Xiao & Swei Sunny Hann
Pages: 5895-5909
Published online: 28 Jun 2019
AbstractforThe emerging roles of PIWI-interacting RNA in human cancers | Full Text | References | PDF (1.2 MB) | EPUB
  • 172 Views
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Article
The impact of panitumumab treatment on survival and quality of life in patients with RAS wild-type metastatic colorectal cancer
Francesca Battaglin, Alberto Puccini, Selma Ahcene Djaballah & Heinz-Josef Lenz
Pages: 5911-5924
Published online: 28 Jun 2019
AbstractforThe impact of panitumumab treatment on survival and quality of life in patients with RAS wild-type metastatic colorectal cancer | Full Text | References | PDF (406.1 KB) | EPUB
  • 140 Views
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Original Research

Article
Effects of dynein light chain Tctex-type 3 on the biological behavior of ovarian cancer
Lulu Zhou, Miaomiao Ye, Fang Xue, Ermei Lu, Lu-Zhe Sun & Xueqiong Zhu
Pages: 5925-5938
Published online: 01 Jul 2019
AbstractforEffects of dynein light chain Tctex-type 3 on the biological behavior of ovarian cancer | Full Text | References | PDF (4 MB) | EPUB
  • 73 Views
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Article
Comparison of short-term and survival outcomes for transanal natural orifice specimen extraction with conventional mini-laparotomy after laparoscopic anterior resection for colorectal cancer
Sicheng Zhou, Xuewei Wang, Chuanduo Zhao, Wei Pei, Haitao Zhou, Qian Liu, Jianwei Liang, Zhixiang Zhou & Xishan Wang
Pages: 5939-5948
Published online: 01 Jul 2019
AbstractforComparison of short-term and survival outcomes for transanal natural orifice specimen extraction with conventional mini-laparotomy after laparoscopic anterior resection for colorectal cancer | Full Text | References | PDF (636.7 KB) | EPUB
  • 81 Views
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Article
Clinical outcomes and survival analysis for petroclival meningioma patients receiving surgical resection: an analysis of 176 cases
Li Qiao, Chunjiang Yu, Hongwei Zhang, Mingshan Zhang, Yanming Qu, Ming Ren, Chunyu Gu & Haoran Wang
Pages: 5949-5959
Published online: 01 Jul 2019
AbstractforClinical outcomes and survival analysis for petroclival meningioma patients receiving surgical resection: an analysis of 176 cases | Full Text | References | PDF (2.1 MB) | EPUB
  • 90 Views
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Review

Review Article
SNHG15: a promising cancer-related long noncoding RNA
Jinfei Tong, Xudong Ma, Hailan Yu & Jianhua Yang
Pages: 5961-5969
Published online: 01 Jul 2019
AbstractforSNHG15: a promising cancer-related long noncoding RNA | Full Text | References | PDF (914.8 KB) | EPUB
  • 99 Views
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Original Research

Article
Mechanism of trastuzumab resistance caused by HER-2 mutation in breast carcinomas
Xiangyi Kong, Kai Zhang, Xiangyu Wang, Xue Yang, Yalun Li, Jie Zhai, Zeyu Xing, Yihang Qi, Ran Gao, Xiaoli Feng, Jing Wang & Yi Fang
Pages: 5971-5982
Published online: 02 Jul 2019
AbstractforMechanism of trastuzumab resistance caused by HER-2 mutation in breast carcinomas | Full Text | References | PDF (3 MB) | EPUB
  • 221 Views
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Article
Long noncoding RNA Linc00460 promotes breast cancer progression by regulating the miR-489-5p/FGF7/AKT axis
Yong Zhu, Leiyan Yang, Qing-Yun Chong, Hong Yan, Weijie Zhang, Wenchang Qian, Sheng Tan, Zhengsheng Wu, Peter E Lobie & Tao Zhu
Pages: 5983-6001
Published online: 01 Jul 2019
AbstractforLong noncoding RNA Linc00460 promotes breast cancer progression by regulating the miR-489-5p/FGF7/AKT axis | Full Text | References | PDF (5 MB) | EPUB
  • 97 Views
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Article
Neutrophil–lymphocyte ratio dynamics are useful for distinguishing between recurrence and pseudoprogression in high-grade gliomas
Yong Huang, Haixia Ding, Qiuji Wu, Zhiqiang Li, Huan Li, Sirui Li, Conghua Xie & Yahua Zhong
Pages: 6003-6009
Published online: 01 Jul 2019
AbstractforNeutrophil–lymphocyte ratio dynamics are useful for distinguishing between recurrence and pseudoprogression in high-grade gliomas | Full Text | References | PDF (1.3 MB) | EPUB
  • 52 Views
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Article
Postoperative morbidity and mortality after neoadjuvant chemotherapy versus upfront surgery for locally advanced gastric cancer: a propensity score matching analysis
Liucheng Wu, Lianying Ge, Yuzhou Qin, Mingwei Huang, Jiansi Chen, Yang Yang & Jianhong Zhong
Pages: 6011-6018
Published online: 03 Jul 2019
AbstractforPostoperative morbidity and mortality after neoadjuvant chemotherapy versus upfront surgery for locally advanced gastric cancer: a propensity score matching analysis | Full Text | References | PDF (333.2 KB) | EPUB
  • 75 Views
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Article
Heterogeneity of targeted lung lesion predicts platinum-based first-line therapy outcomes and overall survival for metastatic triple-negative breast cancer patients with lung metastasis: a “PET biopsy” method
Yizhao Xie, Bingxin Gu, Xichun Hu, Yingjian Zhang, Jian Zhang, Zhonghua Wang, Yannan Zhao, Chengcheng Gong, Yi Li, Zhongyi Yang & Biyun Wang
Pages: 6019-6027
Published online: 02 Jul 2019
AbstractforHeterogeneity of targeted lung lesion predicts platinum-based first-line therapy outcomes and overall survival for metastatic triple-negative breast cancer patients with lung metastasis: a “PET biopsy” method | Full Text | References | PDF (952.4 KB) | EPUB
  • 82 Views
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Article
Benefit of adjuvant chemoradiotherapy in patients with pathological stage III gastric cancer
Gui-Fen Ma, Hai-Ge Zhang, Juan Liu, Yi-Xing Chen, Han Xiao, Xue-Fei Wang, Jian He, Zhao-Chong Zeng, Jing Sun & Tian-Shu Liu
Pages: 6029-6041
Published online: 02 Jul 2019
AbstractforBenefit of adjuvant chemoradiotherapy in patients with pathological stage III gastric cancer | Full Text | References | PDF (1.8 MB) | EPUB
  • 56 Views
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Article
RETRACTED ARTICLE: Silencing of LINC01116 suppresses the development of oral squamous cell carcinoma by up-regulating microRNA-136 to inhibit FN1
Zhifeng Chen, Qian Tao, Bin Qiao & Leitao Zhang
Pages: 6043-6059
Published online: 03 Jul 2019
AbstractforRETRACTED ARTICLE: Silencing of LINC01116 suppresses the development of oral squamous cell carcinoma by up-regulating microRNA-136 to inhibit FN1 | PDF (4 MB)
  • 29 Views
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Article
Integrative analysis of the lncRNA-associated ceRNA network reveals lncRNAs as potential prognostic biomarkers in human muscle-invasive bladder cancer
Lei Lyu, Wei Xiang, Jin-Yan Zhu, Tao Huang, Jing-Dong Yuan & Chuan-Hua Zhang
Pages: 6061-6077
Published online: 04 Jul 2019
AbstractforIntegrative analysis of the lncRNA-associated ceRNA network reveals lncRNAs as potential prognostic biomarkers in human muscle-invasive bladder cancer | Full Text | References | PDF (7.8 MB) | EPUB
  • 80 Views
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Article
Transcription factor Nrf2 induces the up-regulation of lncRNA TUG1 to promote progression and adriamycin resistance in urothelial carcinoma of the bladder
Zhulei Sun, Gui Huang & Hepeng Cheng
Pages: 6079-6090
Published online: 04 Jul 2019
Abstractfor Transcription factor Nrf2 induces the up-regulation of lncRNA TUG1 to promote progression and adriamycin resistance in urothelial carcinoma of the bladder | Full Text | References | PDF (2.4 MB) | EPUB
  • 87 Views
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Article
Association of lung and heart dose with survival in patients with non-small cell lung cancer underwent volumetric modulated arc therapy
Lanxiao Shen, Cong Liu, Juebin Jin, Ce Han, Yongqiang Zhou, Xiaomin Zheng, Changfei Gong, Mengfeng Chen, Congying Xie & Xiance Jin
Pages: 6091-6098
Published online: 03 Jul 2019
AbstractforAssociation of lung and heart dose with survival in patients with non-small cell lung cancer underwent volumetric modulated arc therapy | Full Text | References | PDF (1.2 MB) | EPUB
  • 71 Views
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Article
Arm port vs chest port: a systematic review and meta-analysis
Guanhua Li, Yu Zhang, Hongmin Ma & Junmeng Zheng
Pages: 6099-6112
Published online: 03 Jul 2019
AbstractforArm port vs chest port: a systematic review and meta-analysis | Full Text | References | PDF (5.3 MB) | EPUB
  • 457 Views
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Article
Efficacy and safety of intraperitoneally administered resveratrol against rat orthotopic ovarian cancers
Li-Xia Zhong, Mo-Li Wu, Hong Li, Jia Liu & Li-Zhu Lin
Pages: 6113-6124
Published online: 04 Jul 2019
AbstractforEfficacy and safety of intraperitoneally administered resveratrol against rat orthotopic ovarian cancers | Full Text | References | PDF (3.2 MB) | EPUB
  • 88 Views
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Article
M2 macrophage infiltration into tumor islets leads to poor prognosis in non-small-cell lung cancer
Lili Cao, Xiaofang Che, Xueshan Qiu, Zhi Li, Bowen Yang, Shuo Wang, Kezuo Hou, Yibo Fan, Xiujuan Qu & Yunpeng Liu
Pages: 6125-6138
Published online: 04 Jul 2019
AbstractforM2 macrophage infiltration into tumor islets leads to poor prognosis in non-small-cell lung cancer | Full Text | References | PDF (3.9 MB) | EPUB
  • 120 Views
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Article
Prognostic analysis of patients with mutant and wild-type EGFR gene lung adenocarcinoma
Hongmei Zheng, Yuting Zhang, Yuting Zhan, Sile Liu, Junmi Lu, Juan Feng, Xia Wu, Qiuyuan Wen & Songqing Fan
Pages: 6139-6150
Published online: 04 Jul 2019
AbstractforPrognostic analysis of patients with mutant and wild-type EGFR gene lung adenocarcinoma | Full Text | References | PDF (1.2 MB) | EPUB
  • 80 Views
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Article
New serum biomarker identification and analysis by mass spectrometry in cervical precancerous lesion and acute cervicitis in South China
Feng Qiu, Bingsen Su, Zhao Li, Wenke Chen, Longbing Cao, Fu Chen, Dongdong Liu, Jingling He & Ni Lin
Pages: 6151-6162
Published online: 04 Jul 2019
AbstractforNew serum biomarker identification and analysis by mass spectrometry in cervical precancerous lesion and acute cervicitis in South China | Full Text | References | PDF (2.4 MB) | EPUB
  • 79 Views
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Review

Article
Modified Glasgow prognostic score as a prognostic factor for renal cell carcinomas: a systematic review and meta-analysis
Xu Hu, Yan Wang, Wei-Xiao Yang, Wei-Chao Dou, Yan-Xiang Shao & Xiang Li
Pages: 6163-6173
Published online: 04 Jul 2019
AbstractforModified Glasgow prognostic score as a prognostic factor for renal cell carcinomas: a systematic review and meta-analysis | Full Text | References | PDF (2.4 MB) | EPUB
  • 83 Views
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Article
Plasma long noncoding RNAs PANDAR, FOXD2-AS1, and SMARCC2 as potential novel diagnostic biomarkers for gastric cancer
Ziwei Yang, Yanfei Sun, Rongfeng Liu, Yanyan Shi & Shigang Ding
Pages: 6175-6184
Published online: 04 Jul 2019
AbstractforPlasma long noncoding RNAs PANDAR, FOXD2-AS1, and SMARCC2 as potential novel diagnostic biomarkers for gastric cancer | Full Text | References | PDF (930.9 KB) | EPUB
  • 79 Views
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Article
The β-galactoside α2,6-sialyltranferase 1 (ST6GAL1) inhibits the colorectal cancer metastasis by stabilizing intercellular adhesion molecule-1 via sialylation
Leqi Zhou, Sen Zhang, Xia Zou, Jishun Lu, Xiao Yang, Zhijue Xu, Aidong Shan, Wenjuan Jia, Feng Liu, Xialin Yan, Hao Su, Tao Liang, Minhua Zheng, Yan Zhang & Bo Feng
Pages: 6185-6199
Published online: 04 Jul 2019
AbstractforThe β-galactoside α2,6-sialyltranferase 1 (ST6GAL1) inhibits the colorectal cancer metastasis by stabilizing intercellular adhesion molecule-1 via sialylation | Full Text | References | PDF (4.8 MB) | EPUB
  • 98 Views
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Article
LincRNA-p21 leads to G1 arrest by p53 pathway in esophageal squamous cell carcinoma
Ying Zhang, Yan Miao, Muhe Shang, Mxin Liu, Ran Liu, Ench Pan, Yuepu Pu & Lihong Yin
Pages: 6201-6214
Published online: 04 Jul 2019
AbstractforLincRNA-p21 leads to G1 arrest by p53 pathway in esophageal squamous cell carcinoma | Full Text | References | PDF (3.2 MB) | EPUB
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Article
Analysis of the circular RNA transcriptome in the grade 3 endometrial cancer
Fei Ye, Qiong Lan Tang, Fang Ma, Lei Cai, Ming Chen, Xiao Xia Ran, Xiao Yu Wang & Xue Feng Jiang
Pages: 6215-6227
Published online: 05 Jul 2019
AbstractforAnalysis of the circular RNA transcriptome in the grade 3 endometrial cancer | Full Text | References | PDF (3.9 MB) | EPUB
  • 85 Views
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Article
Mechanisms of resistance to a PI3K inhibitor in gastrointestinal stromal tumors: an omic approach to identify novel druggable targets
Gloria Ravegnini, Giulia Sammarini, Sebastian Moran, Giovanni Calice, Valentina Indio, Milena Urbini, Annalisa Astolfi, Federica Zanotti, Maria A Pantaleo, Patrizia Hrelia & Sabrina Angelini
Pages: 6229-6244
Published online: 05 Jul 2019
AbstractforMechanisms of resistance to a PI3K inhibitor in gastrointestinal stromal tumors: an omic approach to identify novel druggable targets | Full Text | References | PDF (2.7 MB) | EPUB
  • 92 Views
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Review

Article
YAP/TAZ: a promising target for squamous cell carcinoma treatment
Xiaoming Dong, Lingbin Meng, Pinyi Liu, Rui Ji, Xuling Su, Ying Xin & Xin Jiang
Pages: 6245-6252
Published online: 08 Jul 2019
AbstractforYAP/TAZ: a promising target for squamous cell carcinoma treatment | Full Text | References | PDF (359.6 KB) | EPUB
  • 94 Views
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Original Research

Article
The development of a nomogram to predict post-radiation necrosis in nasopharyngeal carcinoma patients: a large-scale cohort study
Xiao-Yun Li, Xue-Song Sun, Sai-Lan Liu, Qiu-Yan Chen, Shan-Shan Guo, Li-Ting Liu, Jin-Jie Yan, Hao-Jun Xie, Qing-Nan Tang, Yu-Jing Liang, Ling Guo, Lin-Quan Tang & Hai-Qiang Mai
Pages: 6253-6263
Published online: 08 Jul 2019
AbstractforThe development of a nomogram to predict post-radiation necrosis in nasopharyngeal carcinoma patients: a large-scale cohort study | Full Text | References | PDF (560.3 KB) | EPUB
  • 96 Views
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Article
Identifying risk factors for high-dose methotrexate-induced toxicities in children with acute lymphoblastic leukemia
Xiao Li, Zhongguo Sui, Fanbo Jing, Wen Xu, Xiangpeng Li, Qie Guo, Shuhong Sun & Xiaolin Bi
Pages: 6265-6274
Published online: 05 Jul 2019
AbstractforIdentifying risk factors for high-dose methotrexate-induced toxicities in children with acute lymphoblastic leukemia | Full Text | References | PDF (463.7 KB) | EPUB
  • 180 Views
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Article
Frequency of germline mutations in BRCA1 and BRCA2 in ovarian cancer patients and their effect on treatment outcome
Mohamed Ashour & Hanan Ezzat Shafik
Pages: 6275-6284
Published online: 08 Jul 2019
AbstractforFrequency of germline mutations in BRCA1 and BRCA2 in ovarian cancer patients and their effect on treatment outcome | Full Text | References | PDF (733.6 KB) | EPUB
  • 118 Views
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Open Access
Article
Correlation between pelvic bone marrow radiation dose and acute hematological toxicity in cervical cancer patients treated with concurrent chemoradiation
T Kumar, A Schernberg, F Busato, M Laurans, I Fumagalli, I Dumas, E Deutsch, C Haie-Meder & C Chargari
Pages: 6285-6297
Published online: 08 Jul 2019
AbstractforCorrelation between pelvic bone marrow radiation dose and acute hematological toxicity in cervical cancer patients treated with concurrent chemoradiation | Full Text | References | PDF (632.2 KB) | EPUB
  • 150 Views
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Article
Radiation therapy-induced reactive oxygen species specifically eliminates CD19+IgA+ B cells in nasopharyngeal carcinoma
Weiwei Li, Luman Wang, Chunying Shen, Tingting Xu, Yiwei Chu & Chaosu Hu
Pages: 6299-6309
Published online: 08 Jul 2019
AbstractforRadiation therapy-induced reactive oxygen species specifically eliminates CD19+IgA+ B cells in nasopharyngeal carcinoma | Full Text | References | PDF (1.2 MB) | EPUB
  • 73 Views
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Article
Screening miRNAs associated with resistance gemcitabine from exosomes in A549 lung cancer cells
Ai-Ling Liang, Shen-Lin Du, Bin Zhang, Jing Zhang, Xuan Ma, Cui-Yun Wu & Yong-Jun Liu
Pages: 6311-6321
Published online: 08 Jul 2019
Abstractfor Screening miRNAs associated with resistance gemcitabine from exosomes in A549 lung cancer cells | Full Text | References | PDF (11.5 MB) | EPUB
  • 108 Views
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Article
Downregulation of TfR1 promotes progression of colorectal cancer via the JAK/STAT pathway
Can Cui, Xiaojing Cheng, Liang Yan, Huirong Ding, Xiaoya Guan, Wenlong Zhang, Xiuyun Tian & Chunyi Hao
Pages: 6323-6341
Published online: 09 Jul 2019
AbstractforDownregulation of TfR1 promotes progression of colorectal cancer via the JAK/STAT pathway | Full Text | References | PDF (4.4 MB) | EPUB
  • 125 Views
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Article
Characterization of acquired receptor tyrosine–kinase fusions as mechanisms of resistance to EGFR tyrosine–kinase inhibitors
Haiyuan Xu, Jinge Shen, Jianxing Xiang, Haiyan Li, Bing Li, Tengfei Zhang, Lu Zhang, Xinru Mao, Hong Jian & Yongqian Shu
Pages: 6343-6351
Published online: 09 Jul 2019
Abstractfor Characterization of acquired receptor tyrosine–kinase fusions as mechanisms of resistance to EGFR tyrosine–kinase inhibitors | Full Text | References | PDF (1.6 MB) | EPUB
  • 82 Views
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Article
Alcohol consumption, tobacco smoking, betel quid chewing and oral health associations with hypopharyngeal cancer among men in Central South China: a case–control study
Junfeng Zeng, Yaoyun Tang, Ping Wu, Xing Fang, Wei Wang, Yuhua Fan, Xin Li & Suping Zhao
Pages: 6353-6364
Published online: 10 Jul 2019
AbstractforAlcohol consumption, tobacco smoking, betel quid chewing and oral health associations with hypopharyngeal cancer among men in Central South China: a case–control study | Full Text | References | PDF (397.9 KB) | EPUB
  • 165 Views
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Review

Article
Chinese expert consensus on diagnosis and treatment of nasopharyngeal carcinoma: evidence from current practice and future perspectives
Jinyi Lang, Chaosu Hu, Taixiang Lu, Jianji Pan & Tongyu Lin
Pages: 6365-6376
Published online: 10 Jul 2019
AbstractforChinese expert consensus on diagnosis and treatment of nasopharyngeal carcinoma: evidence from current practice and future perspectives | Full Text | References | PDF (343.3 KB) | EPUB
  • 135 Views
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Letter

Review Article
TMED2 as a marker of prognosis in breast cancer [Letter]
Megan Catherine Schwarz & Silvia Allikmets
Pages: 6377-6378
Published online: 11 Jul 2019
CitationforTMED2 as a marker of prognosis in breast cancer [Letter] | Full Text | References | PDF (173.9 KB) | EPUB
  • 54 Views
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Original Research

Article
DNMT3a promotes proliferation by activating the STAT3 signaling pathway and depressing apoptosis in pancreatic cancer
Wei Jing, Na Song, Yun-Peng Liu, Xiu-Juan Qu, Ya-Fei Qi, Ce Li, Ke-Zuo Hou, Xiao-Fang Che & Xiang-Hong Yang
Pages: 6379-6396
Published online: 10 Jul 2019
AbstractforDNMT3a promotes proliferation by activating the STAT3 signaling pathway and depressing apoptosis in pancreatic cancer | Full Text | References | PDF (3.5 MB) | EPUB
  • 115 Views
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Article
Integrated assessment of PD-L1 expression and molecular classification facilitates therapy selection and prognosis prediction in gastric cancer
Yeqi Sun, Wenwei Yu, Wenbin Guan, Lei Cai, Meng Qiao, Leizhen Zheng, Ruiqi Jiang, Ruifen Wang & Lifeng Wang
Pages: 6397-6410
Published online: 10 Jul 2019
Abstractfor Integrated assessment of PD-L1 expression and molecular classification facilitates therapy selection and prognosis prediction in gastric cancer | Full Text | References | PDF (3.3 MB) | EPUB
  • 114 Views
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Article
Stanniocalcin 2 (STC2) expression promotes post-radiation survival, migration and invasion of nasopharyngeal carcinoma cells
Huocong He, Shuo Qie, Qiaojuan Guo, Shuyang Chen, Changyan Zou, Tianzhu Lu, Ying Su, Jingfeng Zong, Hanchuan Xu, Dan He, Yun Xu, Bijuan Chen, Jianji Pan, Nianli Sang & Shaojun Lin
Pages: 6411-6424
Published online: 11 Jul 2019
AbstractforStanniocalcin 2 (STC2) expression promotes post-radiation survival, migration and invasion of nasopharyngeal carcinoma cells | Full Text | References | PDF (4.2 MB) | EPUB
  • 100 Views
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Article
Predictors of inguinal lymph node metastasis in penile cancer patients: a meta-analysis of retrospective studies
Jiao Hu, Yu Cui, Peihua Liu, Xu Zhou, Wenbiao Ren, Jinbo Chen & Xiongbing Zu
Pages: 6425-6441
Published online: 10 Jul 2019
AbstractforPredictors of inguinal lymph node metastasis in penile cancer patients: a meta-analysis of retrospective studies | Full Text | References | PDF (5.5 MB) | EPUB
  • 89 Views
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Article
TBH score: a new model to predict and prevent severe liver damage after chemotherapy for cancer patients
Mengping Zhang, Yong Bao, Wei Chen, Mengchao Wei, Hui Pang, Yu Feng Ren, Jie Mei, Sheng Ye, Shunjun Fu & Zhen Wei Peng
Pages: 6443-6456
Published online: 11 Jul 2019
AbstractforTBH score: a new model to predict and prevent severe liver damage after chemotherapy for cancer patients | Full Text | References | PDF (2.1 MB) | EPUB
  • 55 Views
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Article
FGF5 promotes osteosarcoma cells proliferation via activating MAPK signaling pathway
Dunxin Han, Mingming Wang, Zhongkai Yu, Long Yin, Changli Liu, Jianmin Wang, Yongjun Liu, Shengyang Jiang, Zhongwu Ren & Jun Yin
Pages: 6457-6466
Published online: 10 Jul 2019
AbstractforFGF5 promotes osteosarcoma cells proliferation via activating MAPK signaling pathway | Full Text | References | PDF (1.9 MB) | EPUB
  • 98 Views
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Article
T cells targeting multiple tumor-associated antigens as a postremission treatment to prevent or delay relapse in acute myeloid leukemia
Lei Xue, Yan Hu, Jian Wang, Xin Liu & Xingbing Wang
Pages: 6467-6476
Published online: 16 Jul 2019
AbstractforT cells targeting multiple tumor-associated antigens as a postremission treatment to prevent or delay relapse in acute myeloid leukemia | Full Text | References | PDF (1.3 MB) | EPUB
  • 76 Views
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Article
Comparison of long-term results between radiotherapy after breast-conserving surgery and postmastectomy radiotherapy in stage T1-2N1M0 breast cancer
Xiao-Wen Lan, Ge Wen, Zhen He, Jiang-Hua Huang, Xue-Bin Zou, Xiao Lin, Yu-Ting Tan & Xiao-Bo Huang
Pages: 6477-6487
Published online: 11 Jul 2019
AbstractforComparison of long-term results between radiotherapy after breast-conserving surgery and postmastectomy radiotherapy in stage T1-2N1M0 breast cancer | Full Text | References | PDF (1.9 MB) | EPUB
  • 84 Views
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Article
Association of ki67 and tumor marker p53 in locally advanced breast cancer patients and evaluation of response to neoadjuvant chemotherapy: a survey in South Iran
Dena Firouzabadi, Alireza Rezvani, Amirreza Dehghanian & Laleh Mahmoudi
Pages: 6489-6497
Published online: 11 Jul 2019
AbstractforAssociation of ki67 and tumor marker p53 in locally advanced breast cancer patients and evaluation of response to neoadjuvant chemotherapy: a survey in South Iran | Full Text | References | PDF (557.8 KB) | EPUB
  • 55 Views
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Article
Circ-ITGA7 sponges miR-3187-3p to upregulate ASXL1, suppressing colorectal cancer proliferation
Guangpu Yang, Tianhao Zhang, Jinning Ye, Jie Yang, Chuangqi Chen, Shirong Cai & Jinping Ma
Pages: 6499-6509
Published online: 12 Jul 2019
AbstractforCirc-ITGA7 sponges miR-3187-3p to upregulate ASXL1, suppressing colorectal cancer proliferation | Full Text | References | PDF (3.7 MB) | EPUB
  • 95 Views
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Article
MicroRNA-218 regulates the chemo-sensitivity of cervical cancer cells through targeting survivin
Minmin Yu, Baozhen Xu, Hui Yang, Songlin Xue, Rong Zhang, Hongmei Zhang, Xiaoyan Ying & Zhiqin Dai
Pages: 6511-6519
Published online: 12 Jul 2019
AbstractforMicroRNA-218 regulates the chemo-sensitivity of cervical cancer cells through targeting survivin | Full Text | References | PDF (1.7 MB) | EPUB
  • 80 Views
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Article
The validation of the 2014 International Society of Urological Pathology (ISUP) grading system for patients with high-risk prostate cancer: a single-center retrospective study
Jiandong Liu, Jinge Zhao, Mengni Zhang, Ni Chen, Guangxi Sun, Yaojing Yang, Xingming Zhang, Junru Chen, Pengfei Shen, Ming Shi & Hao Zeng
Pages: 6521-6529
Published online: 12 Jul 2019
AbstractforThe validation of the 2014 International Society of Urological Pathology (ISUP) grading system for patients with high-risk prostate cancer: a single-center retrospective study | Full Text | References | PDF (693.4 KB) | EPUB
  • 56 Views
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Article
Ectopic expression of HSDL2 is related to cell proliferation and prognosis in breast cancer
Bing Dong, Yang Yang, Anna Han, Songnan Zhang, Zhenhua Lin, Yixuan Wang & Junjie Piao
Pages: 6531-6542
Published online: 12 Jul 2019
AbstractforEctopic expression of HSDL2 is related to cell proliferation and prognosis in breast cancer | Full Text | References | PDF (3.3 MB) | EPUB
  • 58 Views
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Clinical Trial Report

Article
Intercalated combination of chemotherapy and erlotinib for stage IIIA non-small-cell lung cancer: a multicenter, open-label, single-arm, phase II study
Zhiwei Chen, Shengping Shen, Wenbo Shi, Gening Jiang, Xin Wang, Hong Jian, Zhen Zhou, Zhengping Ding & Shun Lu
Pages: 6543-6552
Published online: 12 Jul 2019
AbstractforIntercalated combination of chemotherapy and erlotinib for stage IIIA non-small-cell lung cancer: a multicenter, open-label, single-arm, phase II study | Full Text | References | PDF (1.1 MB) | EPUB
  • 86 Views
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Original Research

Article
Ezrin promotes pancreatic cancer cell proliferation and invasion through activating the Akt/mTOR pathway and inducing YAP translocation
Chunji Quan, Jie Sun, Zhenhua Lin, Tiefeng Jin, Bing Dong, Ziqi Meng & Junjie Piao
Pages: 6553-6566
Published online: 12 Jul 2019
AbstractforEzrin promotes pancreatic cancer cell proliferation and invasion through activating the Akt/mTOR pathway and inducing YAP translocation | Full Text | References | PDF (5.3 MB) | EPUB
  • 90 Views
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Article
The antitumor properties of metformin and phenformin reflect their ability to inhibit the actions of differentiated embryo chondrocyte 1
Chun-Lin Kuo, Shu-Man Hsieh Li, Shu-Yi Liang, Shu-Ting Liu, Li-Chun Huang, Wei-Ming Wang, Li-Chen Yen & Shih-Ming Huang
Pages: 6567-6579
Published online: 15 Jul 2019
AbstractforThe antitumor properties of metformin and phenformin reflect their ability to inhibit the actions of differentiated embryo chondrocyte 1 | Full Text | References | PDF (4.2 MB) | EPUB
  • 81 Views
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Article
Long noncoding RNA DANCR in various cancers: a meta-analysis and bioinformatics
Lihong Wang, Yalin Xie, Hui Fang, Xia Zhang, Huiyun Pan & Senxiang Yan
Pages: 6581-6592
Published online: 15 Jul 2019
AbstractforLong noncoding RNA DANCR in various cancers: a meta-analysis and bioinformatics | Full Text | References | PDF (2.8 MB) | EPUB
  • 63 Views
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Article
Expression and prognostic role of IKBKE and TBK1 in stage I non-small cell lung cancer
Xin Wang, Feifei Teng, Jie Lu, Dianbin Mu, Jianbo Zhang & Jinming Yu
Pages: 6593-6602
Published online: 15 Jul 2019
AbstractforExpression and prognostic role of IKBKE and TBK1 in stage I non-small cell lung cancer | Full Text | References | PDF (1.3 MB) | EPUB
  • 73 Views
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Article
The impact of the patient’s condition, diagnostic procedures and treatment on the survival of carcinoma of unknown primary site patients
Karolina Dorobisz, Iwona Wlodarska-Polinska, Katarzyna Pazdro-Zastawny, Tomasz Rutkowski, Piotr Palka, Tomasz Dworzecki & Tomasz Zatonski
Pages: 6603-6614
Published online: 16 Jul 2019
AbstractforThe impact of the patient’s condition, diagnostic procedures and treatment on the survival of carcinoma of unknown primary site patients | Full Text | References | PDF (326.3 KB) | EPUB
  • 71 Views
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Article
miR-625 reverses multidrug resistance in gastric cancer cells by directly targeting ALDH1A1
Xufei Gong, Baoli Xu, Li Zi & Xinrui Chen
Pages: 6615-6624
Published online: 15 Jul 2019
AbstractformiR-625 reverses multidrug resistance in gastric cancer cells by directly targeting ALDH1A1 | Full Text | References | PDF (3.2 MB) | EPUB
  • 64 Views
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Article
HOXA10 deteriorates gastric cancer through activating JAK1/STAT3 signaling pathway
Wenchao Chen, Gang Wu, Yuanzeng Zhu, Wei Zhang, Han Zhang, Yang Zhou & Peichun Sun
Pages: 6625-6635
Published online: 15 Jul 2019
AbstractforHOXA10 deteriorates gastric cancer through activating JAK1/STAT3 signaling pathway | Full Text | References | PDF (3.6 MB) | EPUB
  • 97 Views
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Article
Paclitaxel-loaded nanobubble targeted to pro-gastrin-releasing peptide inhibits the growth of small cell lung cancer
Jin-Ping Wang, Ji-Ping Yan, Jing Xu, Ting-Hui Yin, Rong-Qin Zheng & Wei Wang
Pages: 6637-6649
Published online: 16 Jul 2019
AbstractforPaclitaxel-loaded nanobubble targeted to pro-gastrin-releasing peptide inhibits the growth of small cell lung cancer | Full Text | References | PDF (5.9 MB) | EPUB
  • 77 Views
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Review

Article
Influence of serum total cholesterol, LDL, HDL, and triglyceride on prostate cancer recurrence after radical prostatectomy
Sheng Cheng, Qiming Zheng, Guoqing Ding & Gonghui Li
Pages: 6651-6661
Published online: 16 Jul 2019
AbstractforInfluence of serum total cholesterol, LDL, HDL, and triglyceride on prostate cancer recurrence after radical prostatectomy | Full Text | References | PDF (1,015.2 KB) | EPUB
  • 96 Views
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Review Article
Efficacy of complementary and integrative medicine on health-related quality of life in cancer patients: a systematic review and meta-analysis
Wan-Fu Lin, Mao-Feng Zhong, Qing-Hui Zhou, Yu-Ren Zhang, Huan Wang, Zhi-Hao Zhao, Bin-Bin Cheng & Chang-Quan Ling
Pages: 6663-6680
Published online: 22 Jul 2019
AbstractforEfficacy of complementary and integrative medicine on health-related quality of life in cancer patients: a systematic review and meta-analysis | Full Text | References | PDF (3.5 MB) | EPUB
  • 348 Views
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Original Research

Article
High expression of proenkephalin is associated with favorable outcomes in patients with gastrointestinal stromal tumors
Defeng Tang, Tianlong Lin, Yangyang Wang & Hui Cao
Pages: 6681-6690
Published online: 17 Jul 2019
AbstractforHigh expression of proenkephalin is associated with favorable outcomes in patients with gastrointestinal stromal tumors | Full Text | References | PDF (3.1 MB) | EPUB
  • 61 Views
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Article
IL-37 induces anti-tumor immunity by indirectly promoting dendritic cell recruitment and activation in hepatocellular carcinoma
Yuan Liu, Jing-Jing Zhao, Zi-Qi Zhou, Qiu-Zhong Pan, Qian Zhu, Yan Tang, Jian-Chuan Xia & De-Sheng Weng
Pages: 6691-6702
Published online: 18 Jul 2019
AbstractforIL-37 induces anti-tumor immunity by indirectly promoting dendritic cell recruitment and activation in hepatocellular carcinoma | Full Text | References | PDF (2 MB) | EPUB
  • 90 Views
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Article
Relationships between expression of BCS1L, mitochondrial bioenergetics, and fatigue among patients with prostate cancer
Chao-Pin Hsiao, Mei-Kuang Chen, Martina L Veigl, Rodney Ellis, Matthew Cooney, Barbara Daly & Charles Hoppel
Pages: 6703-6717
Published online: 18 Jul 2019
AbstractforRelationships between expression of BCS1L, mitochondrial bioenergetics, and fatigue among patients with prostate cancer | Full Text | References | PDF (662.3 KB) | EPUB
  • 79 Views
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Article
Novel variants of unknown significance in the PMS2 gene identified in patients with hereditary colon cancer
Raffaella Liccardo, Carlo Della Ragione, Nunzio Mitilini, Marina De Rosa, Paola Izzo & Francesca Duraturo
Pages: 6719-6725
Published online: 18 Jul 2019
Abstractfor Novel variants of unknown significance in the PMS2 gene identified in patients with hereditary colon cancer | Full Text | References | PDF (1 MB) | EPUB
  • 131 Views
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Article
Expression of endoplasmic reticulum oxidoreductase 1-α in cholangiocarcinoma tissues and its effects on the proliferation and migration of cholangiocarcinoma cells
Wendi Yan, Xue Wang, Tesi Liu, Liyan Chen, Longzhe Han, Jing Xu, Guihua Jin, Kenichi Harada, Zhenhua Lin & Xiangshan Ren
Pages: 6727-6739
Published online: 19 Jul 2019
AbstractforExpression of endoplasmic reticulum oxidoreductase 1-α in cholangiocarcinoma tissues and its effects on the proliferation and migration of cholangiocarcinoma cells | Full Text | References | PDF (3.6 MB) | EPUB
  • 76 Views
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Review

Article
High dose vs low dose irradiation of the subventricular zone in patients with glioblastoma—a systematic review and meta-analysis
Sergiu Şuşman, Daniel-Corneliu Leucuţa, Gabriel Kacso & Ştefan Ioan Florian
Pages: 6741-6753
Published online: 18 Jul 2019
AbstractforHigh dose vs low dose irradiation of the subventricular zone in patients with glioblastoma—a systematic review and meta-analysis | Full Text | References | PDF (992.3 KB) | EPUB
  • 75 Views
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Original Research

Article
MicroRNA-206 inhibits metastasis of triple-negative breast cancer by targeting transmembrane 4 L6 family member 1
Chunni Fan, Ning Liu, Dan Zheng, Jianshi Du & Keren Wang
Pages: 6755-6764
Published online: 22 Jul 2019
Abstractfor MicroRNA-206 inhibits metastasis of triple-negative breast cancer by targeting transmembrane 4 L6 family member 1 | Full Text | References | PDF (2.2 MB) | EPUB
  • 89 Views
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Article
Ultra-late recurrence of non-small cell lung cancer over 10 years after curative resection
Dai Sonoda, Yosuke Matsuura, Junji Ichinose, Masayuki Nakao, Hironori Ninomiya, Mingyon Mun, Yuichi Ishikawa, Ken Nakagawa, Yukitoshi Satoh & Sakae Okumura
Pages: 6765-6774
Published online: 19 Jul 2019
AbstractforUltra-late recurrence of non-small cell lung cancer over 10 years after curative resection | Full Text | References | PDF (1.2 MB) | EPUB
  • 80 Views
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Article
Upregulation of family with sequence similarity 83 member D expression enhances cell proliferation and motility via activation of Wnt/β-catenin signaling and predicts poor prognosis in gastric cancer
Furong Wang, Sigong Zhang, Yucai Wei, Hao Chen, Zuoyi Jiao & Yumin Li
Pages: 6775-6791
Published online: 22 Jul 2019
AbstractforUpregulation of family with sequence similarity 83 member D expression enhances cell proliferation and motility via activation of Wnt/β-catenin signaling and predicts poor prognosis in gastric cancer | Full Text | References | PDF (5.1 MB) | EPUB
  • 69 Views
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Article
Cardiovascular disease-related chronic conditions among Veterans Affairs nonmetastatic colorectal cancer survivors: a matched case–control analysis
Leah L Zullig, Valerie A Smith, Jennifer H Lindquist, Christina D Williams, Morris Weinberger, Dawn Provenzale, George L Jackson, Michael J Kelley, Susanne Danus & Hayden B Bosworth
Pages: 6793-6802
Published online: 22 Jul 2019
AbstractforCardiovascular disease-related chronic conditions among Veterans Affairs nonmetastatic colorectal cancer survivors: a matched case–control analysis | Full Text | References | PDF (335.1 KB) | EPUB
  • 76 Views
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Review

Article
Optimal management of thymic malignancies: current perspectives
Gabrielle Drevet, Stéphane Collaud, François Tronc, Nicolas Girard & Jean-Michel Maury
Pages: 6803-6814
Published online: 22 Jul 2019
AbstractforOptimal management of thymic malignancies: current perspectives | Full Text | References | PDF (2.4 MB) | EPUB
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Original Research

Article
Evaluating the prognostic significance of tumor-infiltrating lymphocytes in solid tumor: practice of a standardized method from the International Immuno-Oncology Biomarkers Working Group
Jiu-Yang Liu, Gui-Fang Yang, Fang-Fang Chen & Chun-Wei Peng
Pages: 6815-6827
Published online: 23 Jul 2019
AbstractforEvaluating the prognostic significance of tumor-infiltrating lymphocytes in solid tumor: practice of a standardized method from the International Immuno-Oncology Biomarkers Working Group | Full Text | References | PDF (4.5 MB) | EPUB
  • 101 Views
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Article
MicroRNA 145 enhances chemosensitivity of glioblastoma stem cells to demethoxycurcumin
Chunfa Qian, Bin Wang, Yuanjie Zou, Yansong Zhang, Xinhua Hu, Wenbo Sun, Hong Xiao, Hongyi Liu & Lei Shi
Pages: 6829-6840
Published online: 24 Jul 2019
AbstractforMicroRNA 145 enhances chemosensitivity of glioblastoma stem cells to demethoxycurcumin | Full Text | References | PDF (3.8 MB) | EPUB
  • 100 Views
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Article
Exploration of exact significance of lymph node ratio and construction of a novel stage in colon cancer with no distant metastasis
Yang Lv, Qing-Yang Feng, Song-Bin Lin, Yi-Hao Mao, Yu-Qiu Xu, Peng Zheng, Liang-Liang Yang, Guo-Dong He & Jian-Min Xu
Pages: 6841-6854
Published online: 24 Jul 2019
AbstractforExploration of exact significance of lymph node ratio and construction of a novel stage in colon cancer with no distant metastasis | Full Text | References | PDF (3.7 MB) | EPUB
  • 55 Views
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Article
Inhibitor of DNA binding 1 (Id1) mediates stemness of colorectal cancer cells through the Id1-c-Myc-PLAC8 axis via the Wnt/β-catenin and Shh signaling pathways
Yanxia Sun, Xiaolan Lai, Yue Yu, Jieyu Li, Lei Cao, Wansong Lin, Chuanzhong Huang, Jinrong Liao, Wei Chen, Chao Li, Chunkang Yang, Mingang Ying, Qiang Chen & Yunbin Ye
Pages: 6855-6869
Published online: 23 Jul 2019
AbstractforInhibitor of DNA binding 1 (Id1) mediates stemness of colorectal cancer cells through the Id1-c-Myc-PLAC8 axis via the Wnt/β-catenin and Shh signaling pathways | Full Text | References | PDF (4 MB) | EPUB
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Article
Prognostic values of baseline, interim and end-of therapy 18F-FDG PET/CT in patients with follicular lymphoma
Yeye Zhou, Zixuan Zhao, Jihui Li, Bin Zhang, Shibiao Sang, Yiwei Wu & Shengming Deng
Pages: 6871-6885
Published online: 23 Jul 2019
Abstractfor Prognostic values of baseline, interim and end-of therapy 18F-FDG PET/CT in patients with follicular lymphoma | Full Text | References | PDF (5.4 MB) | EPUB
  • 105 Views
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Article
Circular RNA hsa_circRNA_102958 promotes tumorigenesis of colorectal cancer via miR-585/CDC25B axis
Rizeng Li, BinBin Wu, Jianfu Xia, Lechi Ye & Xiaoping Yang
Pages: 6887-6893
Published online: 23 Jul 2019
AbstractforCircular RNA hsa_circRNA_102958 promotes tumorigenesis of colorectal cancer via miR-585/CDC25B axis | Full Text | References | PDF (1.7 MB) | EPUB
  • 66 Views
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Article
Association between single nucleotide polymorphisms of NOTCH signaling pathway-related genes and the prognosis of NSCLC
Qiuping Xu, Danhua Lin, Xu Li, Rendong Xiao, Zhiqiang Liu, Weimin Xiong, Lin Cai & Fei He
Pages: 6895-6905
Published online: 24 Jul 2019
AbstractforAssociation between single nucleotide polymorphisms of NOTCH signaling pathway-related genes and the prognosis of NSCLC | Full Text | References | PDF (491.8 KB) | EPUB
  • 70 Views
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Article
Nomograms for predicting overall survival and cancer-specific survival in patients with surgically resected intrahepatic cholangiocarcinoma
Kexin Ma, Bing Dong, Liming Wang, Chongyu Zhao, Zhaoyu Fu, Chi Che, Wuguang Liu, Zexuan Yang & Rui Liang
Pages: 6907-6929
Published online: 24 Jul 2019
AbstractforNomograms for predicting overall survival and cancer-specific survival in patients with surgically resected intrahepatic cholangiocarcinoma | Full Text | References | PDF (6.2 MB) | EPUB
  • 68 Views
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Article
Feasibility and safety of neoadjuvant laparoscopic hyperthermic intraperitoneal chemotherapy in patients with advanced stage ovarian cancer: a single-center experience
Tian Gao, Xiao-xin Huang, Wu-yun Wang, Miao-fang Wu, Zhong-qiu Lin & Jing Li
Pages: 6931-6940
Published online: 24 Jul 2019
AbstractforFeasibility and safety of neoadjuvant laparoscopic hyperthermic intraperitoneal chemotherapy in patients with advanced stage ovarian cancer: a single-center experience | Full Text | References | PDF (803.5 KB) | EPUB
  • 61 Views
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Article
Predictors of health care use in Australian cancer patients
Rezwanul Hasan Rana, Khorshed Alam, Jeff Gow & Nicholas Ralph
Pages: 6941-6957
Published online: 24 Jul 2019
AbstractforPredictors of health care use in Australian cancer patients | Full Text | References | PDF (483.7 KB) | EPUB
  • 213 Views
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Article
Loss of Cirbp expression is correlated with the malignant progression and poor prognosis in nasopharyngeal carcinoma
Tao-Yan Lin, Yan Chen, Jun-Shuang Jia, Chen Zhou, Mei Lian, Yue-Ting Wen, Xiao-Yan Li, Heng-Wei Chen, Xiao-Lin Lin, Xiao-Ling Zhang, Sheng-Jun Xiao, Yan Sun & Dong Xiao
Pages: 6959-6969
Published online: 24 Jul 2019
AbstractforLoss of Cirbp expression is correlated with the malignant progression and poor prognosis in nasopharyngeal carcinoma | Full Text | References | PDF (4.4 MB) | EPUB
  • 84 Views
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Article
Surgical outcomes and prognostic factors for patients with gastric cancer spinal metastasis
Nanzhe Zhong, Ao Leng, Shaohui He, Minglei Yang, Dan Zhang, Jian Jiao, Wei Xu, Xinghai Yang & Jianru Xiao
Pages: 6971-6979
Published online: 24 Jul 2019
AbstractforSurgical outcomes and prognostic factors for patients with gastric cancer spinal metastasis | Full Text | References | PDF (3.6 MB) | EPUB
  • 87 Views
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Article
Downregulation of miR-216a-5p by long noncoding RNA PVT1 suppresses colorectal cancer progression via modulation of YBX1 expression
Xiang Zeng, Yan Liu, Hongquan Zhu, Di Chen & Weimin Hu
Pages: 6981-6993
Published online: 24 Jul 2019
AbstractforDownregulation of miR-216a-5p by long noncoding RNA PVT1 suppresses colorectal cancer progression via modulation of YBX1 expression | Full Text | References | PDF (3.7 MB) | EPUB
  • 62 Views
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Article
Secreted TGF-beta-induced protein promotes aggressive progression in bladder cancer cells
Jun Zou, Ruiyan Huang, Huajun Li, Bin Wang, Yanfei Chen, Shuwei Chen, Kaifu Ou & Xutao Wang
Pages: 6995-7006
Published online: 25 Jul 2019
AbstractforSecreted TGF-beta-induced protein promotes aggressive progression in bladder cancer cells | Full Text | References | PDF (5.7 MB) | EPUB
  • 117 Views
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Article
Unexpected uterine sarcomas after hysterectomy and myomectomy for presumed leiomyoma: a retrospective study of 26,643 patients
Hanyu Cao, Lin Li, Bowen Yang, Gupo Luo, Jiangyan Lou & Mingrong Xi
Pages: 7007-7014
Published online: 25 Jul 2019
AbstractforUnexpected uterine sarcomas after hysterectomy and myomectomy for presumed leiomyoma: a retrospective study of 26,643 patients | Full Text | References | PDF (648.5 KB) | EPUB
  • 80 Views
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Article
Intraperitoneal cytology after laparoscopic radical hysterectomy with vaginal closure without the use of a manipulator for cervical cancer: a retrospective observational study
Tomohito Tanaka, Shunsuke Miyamoto, Shinichi Terada, Yuhei Kogata, Hiroshi Sasaki, Satoshi Tsunetoh, Takashi Yamada & Masahide Ohmichi
Pages: 7015-7020
Published online: 25 Jul 2019
AbstractforIntraperitoneal cytology after laparoscopic radical hysterectomy with vaginal closure without the use of a manipulator for cervical cancer: a retrospective observational study | Full Text | References | PDF (869.5 KB) | EPUB
  • 72 Views
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Article
Relationship of B7-H3 expression in tumor cells and tumor vasculature with FOXP3+ regulatory T cells in renal cell carcinoma
Kentaro Inamura, Gulanbar Amori, Takeshi Yuasa, Shinya Yamamoto, Junji Yonese & Yuichi Ishikawa
Pages: 7021-7030
Published online: 25 Jul 2019
AbstractforRelationship of B7-H3 expression in tumor cells and tumor vasculature with FOXP3+ regulatory T cells in renal cell carcinoma | Full Text | References | PDF (1.2 MB) | EPUB
  • 120 Views
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Article
Multiple gastrointestinal stromal tumors: analysis of clinicopathologic characteristics and prognosis of 20 patients
Kai Li, WEH Tjhoi, Chunhui Shou, Weili Yang, Qing Zhang, Xiaosun Liu & Jiren Yu
Pages: 7031-7038
Published online: 25 Jul 2019
AbstractforMultiple gastrointestinal stromal tumors: analysis of clinicopathologic characteristics and prognosis of 20 patients | Full Text | References | PDF (450.5 KB) | EPUB
  • 64 Views
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Article
The oncological outcome and influence of neoadjuvant chemotherapy on the surgery in the resectable and locally advanced oral squamous cell carcinoma
Xuan Su, Qing Liu, Jianyin Li, Chuyi Zhang, Zhuming Xue, Caiyun He & Weiwei Liu
Pages: 7039-7046
Published online: 25 Jul 2019
AbstractforThe oncological outcome and influence of neoadjuvant chemotherapy on the surgery in the resectable and locally advanced oral squamous cell carcinoma | Full Text | References | PDF (724.8 KB) | EPUB
  • 84 Views
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Article
iTRAQ-based quantitative protein expression profiling of biomarkers in childhood B-cell and T-cell acute lymphoblastic leukemia
Runhong Yu, Jingyu Zhang, Yuzhu Zang, Li Zeng, Wenli Zuo, Yanliang Bai, Yanhui Liu, Kai Sun & Yufeng Liu
Pages: 7047-7063
Published online: 25 Jul 2019
AbstractforiTRAQ-based quantitative protein expression profiling of biomarkers in childhood B-cell and T-cell acute lymphoblastic leukemia | Full Text | References | PDF (3.1 MB) | EPUB
  • 113 Views
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Article
HOXA10 knockdown inhibits proliferation, induces cell cycle arrest and apoptosis in hepatocellular carcinoma cells through HDAC1
Yi Zhang, Jie Chen, Shan-Shan Wu, Meng-Jiao Lv, Yong-Sheng Yu, Zheng-Hao Tang, Xiao-Hua Chen & Guo-Qing Zang
Pages: 7065-7076
Published online: 26 Jul 2019
AbstractforHOXA10 knockdown inhibits proliferation, induces cell cycle arrest and apoptosis in hepatocellular carcinoma cells through HDAC1 | Full Text | References | PDF (3 MB) | EPUB
  • 89 Views
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Article
PDX1, a key factor in pancreatic embryogenesis, can exhibit antimetastatic activity in pancreatic ductal adenocarcinoma
Liya G Kondratyeva, Dina R Safina, Igor P Chernov, Eugene P Kopantzev, Sergey V Kostrov & Eugene D Sverdlov
Pages: 7077-7087
Published online: 26 Jul 2019
AbstractforPDX1, a key factor in pancreatic embryogenesis, can exhibit antimetastatic activity in pancreatic ductal adenocarcinoma | Full Text | References | PDF (1.8 MB) | EPUB
  • 75 Views
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Article
Role of surgery in patients with early stage small-cell lung cancer
Aimei Peng, Guoshu Li, Mengting Xiong, Shuanshuan Xie & Changhui Wang
Pages: 7089-7101
Published online: 26 Jul 2019
AbstractforRole of surgery in patients with early stage small-cell lung cancer | Full Text | References | PDF (1.8 MB) | EPUB
  • 114 Views
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Article
Diabetes mellitus is a predictive factor for radiation pneumonitis after thoracic radiotherapy in patients with lung cancer
Moonkyoo Kong, Yu Jin Lim, Youngkyong Kim, Mi Joo Chung, Soonki Min, Dong Oh Shin & Weonkuu Chung
Pages: 7103-7110
Published online: 26 Jul 2019
AbstractforDiabetes mellitus is a predictive factor for radiation pneumonitis after thoracic radiotherapy in patients with lung cancer | Full Text | References | PDF (288.1 KB) | EPUB
  • 99 Views
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Article
Silibinin restores the sensitivity of cisplatin and taxol in A2780-resistant cell and reduces drug-induced hepatotoxicity
Zhichun Yang, Qionghui Pan, Dingfang Zhang, Jianqiang Chen, Yinda Qiu, Xiaojing Chen, Feiyun Zheng & Feng Lin
Pages: 7111-7122
Published online: 26 Jul 2019
AbstractforSilibinin restores the sensitivity of cisplatin and taxol in A2780-resistant cell and reduces drug-induced hepatotoxicity | Full Text | References | PDF (3.4 MB) | EPUB
  • 109 Views
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Article
Malignant ascite-derived extracellular vesicles inhibit T cell activity by upregulating Siglec-10 expression
Yujuan Li, Jing Zhou, Qian Zhuo, Jingyun Zhang, Jingyan Xie, Suping Han & Shuli Zhao
Pages: 7123-7134
Published online: 29 Jul 2019
AbstractforMalignant ascite-derived extracellular vesicles inhibit T cell activity by upregulating Siglec-10 expression | Full Text | References | PDF (2.2 MB) | EPUB
  • 97 Views
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Clinical Trial Report

Article
A multi-center, Phase II trial of nab-paclitaxel and gemcitabine in patients with non-small-cell lung cancer previously treated with platinum-based chemotherapy
Motoko Tachihara, Tatsunori Kiriu, Akito Hata, Yukihisa Hatakeyama, Kyosuke Nakata, Tatsuya Nagano, Masatsugu Yamamoto, Kazuyuki Kobayashi, Hisashi Ohnishi, Nobuyuki Katakami & Yoshihiro Nishimura
Pages: 7135-7140
Published online: 29 Jul 2019
AbstractforA multi-center, Phase II trial of nab-paclitaxel and gemcitabine in patients with non-small-cell lung cancer previously treated with platinum-based chemotherapy | Full Text | References | PDF (268.3 KB) | EPUB
  • 71 Views
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Original Research

Article
Laparoscopic surgery facilitates administration of adjuvant chemotherapy in locally advanced colon cancer: propensity score analyses
Karin ATGM Wasmann, Charlotte EL Klaver, Jarmila DW van der Bilt, Susan van Dieren, Iris D Nagtegaal, Cornelis JA Punt, Bert van Ramshorst, Albert M Wolthuis, Johannes HW de Wilt, André D’Hoore, Hjalmar C van Santvoort & Pieter J Tanis
Pages: 7141-7157
Published online: 29 Jul 2019
AbstractforLaparoscopic surgery facilitates administration of adjuvant chemotherapy in locally advanced colon cancer: propensity score analyses | Full Text | References | PDF (1.3 MB) | EPUB
  • 64 Views
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Article
Diagnostic value of angiopoietin-like protein 2 for CHB-related hepatocellular carcinoma
Jiyuan Zhou, Wanna Yang, Shu Zhang, Xuanqiu He, Jiatian Lin, Tao Zhou, Yaqin Li, Guiqiang Wang & Junhui Chen
Pages: 7159-7169
Published online: 29 Jul 2019
AbstractforDiagnostic value of angiopoietin-like protein 2 for CHB-related hepatocellular carcinoma | Full Text | References | PDF (1.9 MB) | EPUB
  • 59 Views
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Article
Impact of bladder volume on treatment planning and clinical outcomes of radiotherapy for patients with cervical cancer
Shanshan Ma, Tingting Zhang, Li Jiang, Wen Qin, Keyu Lu, Yong Zhang & Rensheng Wang
Pages: 7171-7181
Published online: 29 Jul 2019
AbstractforImpact of bladder volume on treatment planning and clinical outcomes of radiotherapy for patients with cervical cancer | Full Text | References | PDF (1,010.5 KB) | EPUB
  • 153 Views
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Case Series

Article
Gain and loss from transcatheter intra-arterial limb infusion of cisplatin for extremity osteosarcoma: a retrospective study of 99 cases in the past six years
Lu Xie, Jie Xu, Sen Dong, Jian Gao, Xiaodong Tang, Taiqiang Yan, Rongli Yang & Wei Guo
Pages: 7183-7195
Published online: 30 Jul 2019
AbstractforGain and loss from transcatheter intra-arterial limb infusion of cisplatin for extremity osteosarcoma: a retrospective study of 99 cases in the past six years | Full Text | References | PDF (4.2 MB) | EPUB
  • 66 Views
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Original Research

Article
HPV infection associated DNA damage correlated with cervical precancerous lesions and cancer in the highest area of cervical cancer mortality, Longnan, China
Jin Zhao, Zhong Guo, Qiang Wang, Tianbin Si, Shuyan Pei, Hongmei Qu, Lina Shang, Yuqing Yang & Lili Wang
Pages: 7197-7210
Published online: 30 Jul 2019
AbstractforHPV infection associated DNA damage correlated with cervical precancerous lesions and cancer in the highest area of cervical cancer mortality, Longnan, China | Full Text | References | PDF (3.6 MB) | EPUB
  • 93 Views
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Article
A multivariable model of BRAFV600E and ultrasonographic features for predicting the risk of central lymph node metastasis in cN0 papillary thyroid microcarcinoma
Bao-Ding Chen, Zheng Zhang, Ke-Ke Wang, Meng-Yuan Shang, Shuang-Shuang Zhao, Wen-Bo Ding, Rui Du, Zhuan Yu & Xi-Ming Xu
Pages: 7211-7217
Published online: 30 Jul 2019
AbstractforA multivariable model of BRAFV600E and ultrasonographic features for predicting the risk of central lymph node metastasis in cN0 papillary thyroid microcarcinoma | Full Text | References | PDF (384.9 KB) | EPUB
  • 65 Views
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Article
Estimation of radiotherapy modalities for patients with stage I-II nasal natural killer T-Cell lymphoma
Xianfeng Liu, Furong Wu, Qishuai Guo, Ying Wang, Yanan He, Huanli Luo, Qicheng Li, Mingsong Zhong, Chao Li, Han Yang, Juan Zhou & Fu Jin
Pages: 7219-7229
Published online: 30 Jul 2019
AbstractforEstimation of radiotherapy modalities for patients with stage I-II nasal natural killer T-Cell lymphoma | Full Text | References | PDF (1.6 MB) | EPUB
  • 51 Views
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Article
Statins induce cell apoptosis through a modulation of AKT/FOXO1 pathway in prostate cancer cells
Jun-Li Deng, Rui Zhang, Ying Zeng, Yuan-Shan Zhu & Guo Wang
Pages: 7231-7242
Published online: 31 Jul 2019
AbstractforStatins induce cell apoptosis through a modulation of AKT/FOXO1 pathway in prostate cancer cells | Full Text | References | PDF (9.3 MB) | EPUB
  • 90 Views
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Article
Prognostic value of lactate dehydrogenase to albumin ratio (LAR) in patients with resectable esophageal squamous cell carcinoma
Ji-Feng Feng, Liang Wang, Xun Yang & You-Hua Jiang
Pages: 7243-7251
Published online: 31 Jul 2019
AbstractforPrognostic value of lactate dehydrogenase to albumin ratio (LAR) in patients with resectable esophageal squamous cell carcinoma | Full Text | References | PDF (1.9 MB) | EPUB
  • 73 Views
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Review

Article
Treatment of non-metastatic castration-resistant prostate cancer: focus on apalutamide
Anita Gul, Jorge A Garcia & Pedro C Barata
Pages: 7253-7262
Published online: 01 Aug 2019
AbstractforTreatment of non-metastatic castration-resistant prostate cancer: focus on apalutamide | Full Text | References | PDF (293.8 KB) | EPUB
  • 104 Views
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Original Research

Article
RETRACTED ARTICLE: Long noncoding RNA SNHG16 silencing inhibits the aggressiveness of gastric cancer via upregulation of microRNA-628-3p and consequent decrease of NRP1
Weifeng Pang, Mingcui Zhai, Yue Wang & Zhiqiang Li
Pages: 7263-7277
Published online: 01 Aug 2019
AbstractforRETRACTED ARTICLE: Long noncoding RNA SNHG16 silencing inhibits the aggressiveness of gastric cancer via upregulation of microRNA-628-3p and consequent decrease of NRP1 | PDF (6.2 MB)
  • 18 Views
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Article
Immunological nomograms predicting prognosis and guiding adjuvant chemotherapy in stage II colorectal cancer
Yang Feng, Yaqi Li, Sanjun Cai & Junjie Peng
Pages: 7279-7294
Published online: 01 Aug 2019
AbstractforImmunological nomograms predicting prognosis and guiding adjuvant chemotherapy in stage II colorectal cancer | Full Text | References | PDF (5.6 MB) | EPUB
  • 68 Views
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Article
Salvage living donor liver transplantation for posthepatectomy recurrence: a higher incidence of recurrence but promising strategy for long-term survival
Kun-Ming Chan, Chih-Hsien Cheng, Tsung-Han Wu, Chen-Fang Lee, Ting-Jung Wu, Hong-Shiue Chou & Wei-Chen Lee
Pages: 7295-7305
Published online: 02 Aug 2019
AbstractforSalvage living donor liver transplantation for posthepatectomy recurrence: a higher incidence of recurrence but promising strategy for long-term survival | Full Text | References | PDF (384.7 KB) | EPUB
  • 66 Views
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Article
LOX-1+ PMN-MDSC enhances immune suppression which promotes glioblastoma multiforme progression
ErQing Chai, Lan Zhang & Changqing Li
Pages: 7307-7315
Published online: 02 Aug 2019
AbstractforLOX-1+ PMN-MDSC enhances immune suppression which promotes glioblastoma multiforme progression | Full Text | References | PDF (2.4 MB) | EPUB
  • 143 Views
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Article
Cellular magnetic resonance imaging: in vivo tracking of gastric cancer cells and detecting of lymph node metastases using microparticles of iron oxide in mice
Jian Chen, Gang Ren, Rong Cai, Xiangru Wu, Ting Gui, Jianxi Zhao, Huali Li & Chen Guo
Pages: 7317-7326
Published online: 02 Aug 2019
AbstractforCellular magnetic resonance imaging: in vivo tracking of gastric cancer cells and detecting of lymph node metastases using microparticles of iron oxide in mice | Full Text | References | PDF (3.5 MB) | EPUB
  • 95 Views
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Review

Article
Sorcin: a novel potential target in therapies of cancers
Xinyi Zhou, Xue Wu & Baoan Chen
Pages: 7327-7336
Published online: 05 Aug 2019
AbstractforSorcin: a novel potential target in therapies of cancers | Full Text | References | PDF (854.3 KB) | EPUB
  • 85 Views
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Original Research

Article
MAPT promoter CpG island hypermethylation is associated with poor prognosis in patients with stage II colorectal cancer
Chuntao Wang, Yanliang Liu, Wenyi Guo, Xu Zhu, Nita Ahuja & Tao Fu
Pages: 7337-7343
Published online: 05 Aug 2019
AbstractforMAPT promoter CpG island hypermethylation is associated with poor prognosis in patients with stage II colorectal cancer | Full Text | References | PDF (375.1 KB) | EPUB
  • 68 Views
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Article
Establishment and validation of an AJCC stage- and histologic grade-based nomogram for pancreatic neuroendocrine tumors after surgical resection
Chuanzhao Zhang, Yanxia Wu, Hongkai Zhuang, Dezhi Li, Ye Lin, Zi Yin, Xin Lu, Baohua Hou & Zhixiang Jian
Pages: 7345-7352
Published online: 05 Aug 2019
AbstractforEstablishment and validation of an AJCC stage- and histologic grade-based nomogram for pancreatic neuroendocrine tumors after surgical resection | Full Text | References | PDF (669 KB) | EPUB
  • 66 Views
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Article
EDNRB isoform 3 confers Temozolomide resistance in A375 melanoma cells by modulating membrane potential, reactive oxygen species and mitochondrial Ca2+
Yun Shan Chen, Fen Liu, Yi Hong Luo, Yue Fan, Fang Gui Xu, Pin Li, Bei Zhou, Xiu Yu Pan, Chi Chiu Wang & Long Cui
Pages: 7353-7367
Published online: 05 Aug 2019
AbstractforEDNRB isoform 3 confers Temozolomide resistance in A375 melanoma cells by modulating membrane potential, reactive oxygen species and mitochondrial Ca2+ | Full Text | References | PDF (2.7 MB) | EPUB
  • 71 Views
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Article
The role of circular RNA hsa_circ_0085616 in proliferation and migration of hepatocellular carcinoma cells
Wenda Li, Xue Zhou, Xiang Wu, Jinxing Wei & Zejian Huang
Pages: 7369-7376
Published online: 05 Aug 2019
AbstractforThe role of circular RNA hsa_circ_0085616 in proliferation and migration of hepatocellular carcinoma cells | Full Text | References | PDF (2.2 MB) | EPUB
  • 51 Views
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Article
F factor plasmid-mediated Epstein-Barr virus genome introduction establishes an EBV positive NPC cell model
Jingling Duan, Yang Yang, Zhen Wu, Shiang Lin, Chen Zhou, Guowen Sheng, Fan Yang, Lihui Bian, Xiaoling Zhang & Shengjun Xiao
Pages: 7377-7389
Published online: 05 Aug 2019
AbstractforF factor plasmid-mediated Epstein-Barr virus genome introduction establishes an EBV positive NPC cell model | Full Text | References | PDF (4.2 MB) | EPUB
  • 72 Views
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Article
Integrative gene expression profiling reveals that dysregulated triple microRNAs confer paclitaxel resistance in non-small cell lung cancer via co-targeting MAPT
Yuanming Cai, Ruxue Jia, Haozhe Xiong, Qun Ren, Weimin Zuo, Tingting Lin, Rong Lin, Yan Lei, Ping Wang, Huiyue Dong, Hu Zhao, Ling Zhu, Yunfeng Fu, Zhiyong Zeng, Wei Zhang & Shuiliang Wang
Pages: 7391-7404
Published online: 05 Aug 2019
AbstractforIntegrative gene expression profiling reveals that dysregulated triple microRNAs confer paclitaxel resistance in non-small cell lung cancer via co-targeting MAPT | Full Text | References | PDF (2.3 MB) | EPUB
  • 68 Views
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Article
Postoperative metastasis prediction based on portal vein circulating tumor cells detected by flow cytometry in periampullary or pancreatic cancer
Lianyuan Tao, Li Su, Chunhui Yuan, Zhaolai Ma, Lingfu Zhang, Shiping Bo, Yunyun Niu, Sijia Lu & Dianrong Xiu
Pages: 7405-7425
Published online: 06 Aug 2019
AbstractforPostoperative metastasis prediction based on portal vein circulating tumor cells detected by flow cytometry in periampullary or pancreatic cancer | Full Text | References | PDF (3.4 MB) | EPUB
  • 86 Views
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Article
Incident cancer risk in dipeptidyl peptidase-4 inhibitor-treated patients with type 2 diabetes mellitus
Yeo Jin Choi, Dae Jung Kim & Sooyoung Shin
Pages: 7427-7438
Published online: 06 Aug 2019
AbstractforIncident cancer risk in dipeptidyl peptidase-4 inhibitor-treated patients with type 2 diabetes mellitus | Full Text | References | PDF (417.8 KB) | EPUB
  • 83 Views
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Article
RETRACTED ARTICLE: Down-regulation of CCL17 in cancer-associated fibroblasts inhibits cell migration and invasion of breast cancer through ERK1/2 pathway
Junjie Li, Chunli Yang, Jingshi Yang & Liqun Zou
Pages: 7439-7453
Published online: 07 Aug 2019
AbstractforRETRACTED ARTICLE: Down-regulation of CCL17 in cancer-associated fibroblasts inhibits cell migration and invasion of breast cancer through ERK1/2 pathway | PDF (5.9 MB)
  • 25 Views
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Article
The relevance between the immune response-related gene module and clinical traits in head and neck squamous cell carcinoma
Yidan Song, Yihua Pan & Jun Liu
Pages: 7455-7472
Published online: 06 Aug 2019
AbstractforThe relevance between the immune response-related gene module and clinical traits in head and neck squamous cell carcinoma | Full Text | References | PDF (6.1 MB) | EPUB
  • 101 Views
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Article
Identification of a novel DNA repair-related prognostic signature predicting survival of patients with hepatocellular carcinoma
Na Li, Lan Zhao, Chunyan Guo, Chang Liu & Yongyu Liu
Pages: 7473-7484
Published online: 06 Aug 2019
AbstractforIdentification of a novel DNA repair-related prognostic signature predicting survival of patients with hepatocellular carcinoma | Full Text | References | PDF (3 MB) | EPUB
  • 82 Views
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Article
Overexpression of KRT17 promotes proliferation and invasion of non-small cell lung cancer and indicates poor prognosis
Zhao Wang, Mai-Qing Yang, Lei Lei, Liang-Ru Fei, Yi-Wen Zheng, Wen-Jing Huang, Zhi-Han Li, Chen-Chen Liu & Hong-Tao Xu
Pages: 7485-7497
Published online: 07 Aug 2019
AbstractforOverexpression of KRT17 promotes proliferation and invasion of non-small cell lung cancer and indicates poor prognosis | Full Text | References | PDF (8.9 MB) | EPUB
  • 141 Views
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Article
The prognostic value of the postoperative serum CEA levels/preoperative serum CEA levels ratio in colorectal cancer patients with high preoperative serum CEA levels
Hai-Lun Xie, Yi-Zhen Gong, Jia-An Kuang, Feng Gao, Shuang-Yi Tang & Jia-Liang Gan
Pages: 7499-7511
Published online: 07 Aug 2019
AbstractforThe prognostic value of the postoperative serum CEA levels/preoperative serum CEA levels ratio in colorectal cancer patients with high preoperative serum CEA levels | Full Text | References | PDF (2.4 MB) | EPUB
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Corrigendum

Correction
c-MYC expression in T (III/IV) stage oral squamous cell carcinoma (OSCC) patients [Corrigendum]
Page: 7513
Published online: 07 Aug 2019
Citationforc-MYC expression in T (III/IV) stage oral squamous cell carcinoma (OSCC) patients [Corrigendum] | Full Text | PDF (147.8 KB) | EPUB
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Article
Predictive value of preoperative neutrophil-to-lymphocyte ratio in non-metastatic papillary renal cell carcinoma patients after receiving curative surgery
Xiang Tu, Fan Wang, Tiancong Chang, Chichen Zhang, Mengni Zhang, Zhenhua Liu, Shi Qiu, Lu Yang & Qiang Wei
Pages: 7515-7524
Published online: 07 Aug 2019
AbstractforPredictive value of preoperative neutrophil-to-lymphocyte ratio in non-metastatic papillary renal cell carcinoma patients after receiving curative surgery | Full Text | References | PDF (731.7 KB) | EPUB
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Review

Article
Precision oncology: lessons learned and challenges for the future
Hsih-Te Yang, Ronak H Shah, David Tegay & Kenan Onel
Pages: 7525-7536
Published online: 07 Aug 2019
AbstractforPrecision oncology: lessons learned and challenges for the future | Full Text | References | PDF (1.2 MB) | EPUB
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Review Article
Spotlight on telotristat ethyl for the treatment of carcinoid syndrome diarrhea: patient selection and reported outcomes
Cristina Saavedra, Jorge Barriuso, Mairéad G McNamara, Juan W Valle & Angela Lamarca
Pages: 7537-7556
Published online: 08 Aug 2019
AbstractforSpotlight on telotristat ethyl for the treatment of carcinoid syndrome diarrhea: patient selection and reported outcomes | Full Text | References | PDF (2.3 MB) | EPUB
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Article
Sanguinarine exhibits potent efficacy against cervical cancer cells through inhibiting the STAT3 pathway in vitro and in vivo
Huijuan Zhang, Jing Zhang, Puja S Venkat, Chenglei Gu & Yuanguang Meng
Pages: 7557-7566
Published online: 14 Aug 2019
AbstractforSanguinarine exhibits potent efficacy against cervical cancer cells through inhibiting the STAT3 pathway in vitro and in vivo | Full Text | References | PDF (2.4 MB) | EPUB
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Article
The prognostic value of preoperative controlling nutritional status score in non-metastatic renal cell carcinoma treated with surgery: a retrospective single-institution study
Haifeng Song, Ben Xu, Cheng Luo, Zhenan Zhang, Binglei Ma, Jie Jin & Qian Zhang
Pages: 7567-7575
Published online: 09 Aug 2019
AbstractforThe prognostic value of preoperative controlling nutritional status score in non-metastatic renal cell carcinoma treated with surgery: a retrospective single-institution study | Full Text | References | PDF (714.2 KB) | EPUB
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Article
Role of Hippo/YAP signaling in irradiation-induced glioma cell apoptosis
Xiaofei Xu, Yan Chen, Xi Wang & Xingguo Mu
Pages: 7577-7585
Published online: 09 Aug 2019
AbstractforRole of Hippo/YAP signaling in irradiation-induced glioma cell apoptosis | Full Text | References | PDF (2.5 MB) | EPUB
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Article
Morbidity and associated factors of depressive disorder in patients with lung cancer
Yu Lee, Pao-Yen Lin, Meng-Chih Lin, Chin-Chou Wang, Hung-I Lu, Yung-Che Chen, Mian-Yoon Chong & Chi-Fa Hung
Pages: 7587-7596
Published online: 09 Aug 2019
AbstractforMorbidity and associated factors of depressive disorder in patients with lung cancer | Full Text | References | PDF (288.2 KB) | EPUB
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Article
Significance of the neutrophil-to-lymphocyte ratio in young patients with oral squamous cell carcinoma
Baixia Zhang, Wei Du, Kang Gan, Qigen Fang & Xu Zhang
Pages: 7597-7603
Published online: 09 Aug 2019
AbstractforSignificance of the neutrophil-to-lymphocyte ratio in young patients with oral squamous cell carcinoma | Full Text | References | PDF (515.9 KB) | EPUB
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Article
Programmed cell death 1 expression and Epstein-Barr virus infection in chronic lymphocytic leukaemia: a prospective cohort study
Ewelina Grywalska, Marcin Pasiarski, Barbara Sosnowska-Pasiarska, Paweł Macek, Agnieszka Rolińska, Marzena Samardakiewicz, Jarosław Ludian, Stanisław Góźdź & Jacek Roliński
Pages: 7605-7618
Published online: 12 Aug 2019
AbstractforProgrammed cell death 1 expression and Epstein-Barr virus infection in chronic lymphocytic leukaemia: a prospective cohort study | Full Text | References | PDF (9.1 MB) | EPUB
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Erratum

Correction
Role of surgery in patients with early stage small-cell lung cancer [Erratum]
Pages: 7619-7620
Published online: 12 Aug 2019
Citationfor Role of surgery in patients with early stage small-cell lung cancer [Erratum] | Full Text | PDF (157.7 KB) | EPUB
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Article
The Hedgehog signal transducer Smoothened and microRNA-326: pathogenesis and regulation of drug resistance in pediatric B-cell acute lymphoblastic leukemia
Zahra Sheybani, Soheila Rahgozar & Elaheh Sadat Ghodousi
Pages: 7621-7630
Published online: 12 Aug 2019
AbstractforThe Hedgehog signal transducer Smoothened and microRNA-326: pathogenesis and regulation of drug resistance in pediatric B-cell acute lymphoblastic leukemia | Full Text | References | PDF (920.8 KB) | EPUB
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Article
Prognostic significance of preoperative albumin-to-globulin ratio and prognostic nutritional index combined score in Siewert type 3 adenocarcinoma of esophagogastric junction
Yimin Wang, Ziyu Zhu, Chunfeng Li, Yan Ma, Qi You, Zhiguo Li, Hongfeng Zhang, Hongjiang Song & Yingwei Xue
Pages: 7631-7638
Published online: 14 Aug 2019
AbstractforPrognostic significance of preoperative albumin-to-globulin ratio and prognostic nutritional index combined score in Siewert type 3 adenocarcinoma of esophagogastric junction | Full Text | References | PDF (1 MB) | EPUB
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Article
Clinical characteristics of testicular seminoma in individuals in West China: a 10-year follow-up study
Zeyu Chen, Shi Qiu, Dehong Cao, Jianbing Guo, Bo Chen, Yin Huang, Li Lai, Yige Bao, Qiang Dong, Liangren Liu & Qiang Wei
Pages: 7639-7645
Published online: 14 Aug 2019
AbstractforClinical characteristics of testicular seminoma in individuals in West China: a 10-year follow-up study | Full Text | References | PDF (3.3 MB) | EPUB
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Article
Infiltrating CD4 and CD8 lymphocytes in HPV infected uterine cervical milieu
Ninu Maskey, Niresh Thapa, Muna Maharjan, Girishma Shrestha, Narayani Maharjan, Hongbing Cai & Shangqin Liu
Pages: 7647-7655
Published online: 14 Aug 2019
AbstractforInfiltrating CD4 and CD8 lymphocytes in HPV infected uterine cervical milieu | Full Text | References | PDF (1.1 MB) | EPUB
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Article
BHLHE41 promotes U87 and U251 cell proliferation via ERK/cyclinD1 signaling pathway
Chen Wang, Na Zhao, Qin Zheng, Di Zhang & Yang Liu
Pages: 7657-7672
Published online: 14 Aug 2019
AbstractforBHLHE41 promotes U87 and U251 cell proliferation via ERK/cyclinD1 signaling pathway | Full Text | References | PDF (5.6 MB) | EPUB
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Article
Correlation of NRF2 and progesterone receptor and its effects on ovarian cancer biology
Bastian Czogalla, Maja Kahaly, Doris Mayr, Elisa Schmoeckel, Beate Niesler, Anna Hester, Christine Zeder-Göß, Thomas Kolben, Alexander Burges, Sven Mahner, Udo Jeschke & Fabian Trillsch
Pages: 7673-7684
Published online: 14 Aug 2019
AbstractforCorrelation of NRF2 and progesterone receptor and its effects on ovarian cancer biology | Full Text | References | PDF (2.5 MB) | EPUB
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Review

Review Article
The prognostic value and mechanisms of lncRNA UCA1 in human cancer
Fei Yao, Qiang Wang & Qingming Wu
Pages: 7685-7696
Published online: 14 Aug 2019
AbstractforThe prognostic value and mechanisms of lncRNA UCA1 in human cancer | Full Text | References | PDF (1.2 MB) | EPUB
  • 124 Views
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Article
Prognostic significance of FA score based on plasma fibrinogen and serum albumin in patients with epithelial ovarian cancer
Yuan Li, Jia-Ni Yang, Shan-Shan Cheng & Yu Wang
Pages: 7697-7705
Published online: 14 Aug 2019
AbstractforPrognostic significance of FA score based on plasma fibrinogen and serum albumin in patients with epithelial ovarian cancer | Full Text | References | PDF (1.3 MB) | EPUB
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Article
Prospect of immunotherapy combined with anti-angiogenic agents in patients with advanced non-small cell lung cancer
Hongge Liang & Mengzhao Wang
Pages: 7707-7719
Published online: 15 Aug 2019
Abstractfor Prospect of immunotherapy combined with anti-angiogenic agents in patients with advanced non-small cell lung cancer | Full Text | References | PDF (328.7 KB) | EPUB
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Article
OSM-induced CD44 contributes to breast cancer metastatic potential through cell detachment but not epithelial-mesenchymal transition
Hunter Covert, Liliana F Mellor, Cody L Wolf, Nicole Ankenbrandt, Jacqueline M Emathinger, Ken Tawara, Julie Thom Oxford & Cheryl L Jorcyk
Pages: 7721-7737
Published online: 15 Aug 2019
AbstractforOSM-induced CD44 contributes to breast cancer metastatic potential through cell detachment but not epithelial-mesenchymal transition | Full Text | References | PDF (4.7 MB) | EPUB
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Article
Long non-coding RNA NNT-AS1 functions as an oncogenic gene through modulating miR-485/BCL9 in cholangiocarcinoma
Lining Huang, Xingming Jiang, Pengcheng Kang, Zhidong Wang, Kaiming Leng, Daolin Ji, Yi Xu, Hao Wang & Yunfu Cui
Pages: 7739-7749
Published online: 15 Aug 2019
AbstractforLong non-coding RNA NNT-AS1 functions as an oncogenic gene through modulating miR-485/BCL9 in cholangiocarcinoma | Full Text | References | PDF (3.2 MB) | EPUB
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Article
Combined ultrasound/computed tomography guidance in percutaneous radiofrequency ablation after transarterial chemoembolization for hepatocellular carcinoma in the hepatic dome
Xuefeng Kan, Yong Wang, Ping Han, Qi Yao, Kun Qian, Bin Xiong & Chuansheng Zheng
Pages: 7751-7757
Published online: 15 Aug 2019
AbstractforCombined ultrasound/computed tomography guidance in percutaneous radiofrequency ablation after transarterial chemoembolization for hepatocellular carcinoma in the hepatic dome | Full Text | References | PDF (488.3 KB) | EPUB
  • 73 Views
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Article
Impact of sites versus number of metastases on survival of patients with organ metastasis from newly diagnosed cervical cancer
Zhuomin Yin, Huarong Tang, Li Li, Juan Ni, Shuhui Yuan, Hanmei Lou & Ming Chen
Pages: 7759-7766
Published online: 16 Aug 2019
AbstractforImpact of sites versus number of metastases on survival of patients with organ metastasis from newly diagnosed cervical cancer | Full Text | References | PDF (391.4 KB) | EPUB
  • 106 Views
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Article
Intensity-modulated carbon-ion radiation therapy versus intensity-modulated photon-based radiation therapy in locally recurrent nasopharyngeal carcinoma: a dosimetric comparison
Lei Wang, Jiyi Hu, Xiaoli Liu, Weiwei Wang, Lin Kong & Jiade J Lu
Pages: 7767-7777
Published online: 16 Aug 2019
AbstractforIntensity-modulated carbon-ion radiation therapy versus intensity-modulated photon-based radiation therapy in locally recurrent nasopharyngeal carcinoma: a dosimetric comparison | Full Text | References | PDF (2.5 MB) | EPUB
  • 134 Views
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Review

Article
Impact of tivozanib on patient outcomes in treatment of advanced renal cell carcinoma
Suayib Yalcin & Sahin Lacin
Pages: 7779-7785
Published online: 16 Aug 2019
AbstractforImpact of tivozanib on patient outcomes in treatment of advanced renal cell carcinoma | Full Text | References | PDF (855.1 KB) | EPUB
  • 60 Views
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Article
Fruquintinib: a novel antivascular endothelial growth factor receptor tyrosine kinase inhibitor for the treatment of metastatic colorectal cancer
Ying Zhang, Jia-Yun Zou, Zhe Wang & Ying Wang
Pages: 7787-7803
Published online: 16 Aug 2019
AbstractforFruquintinib: a novel antivascular endothelial growth factor receptor tyrosine kinase inhibitor for the treatment of metastatic colorectal cancer | Full Text | References | PDF (1.3 MB) | EPUB
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Article
Phyllodes tumor of the breast: diagnosis, management and outcome during a 10-year experience
Chagkrit Ditsatham & Wilaiwan Chongruksut
Pages: 7805-7811
Published online: 19 Aug 2019
AbstractforPhyllodes tumor of the breast: diagnosis, management and outcome during a 10-year experience | Full Text | References | PDF (1.9 MB) | EPUB
  • 259 Views
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Article
Overexpressed PKMYT1 promotes tumor progression and associates with poor survival in esophageal squamous cell carcinoma
Qingyi Zhang, Xuan Zhao, Chaoqi Zhang, Wei Wang, Feng Li, Donglei Liu, Kai Wu, Dengyan Zhu, Shasha Liu, Chunyi Shen, Xin Yuan, Kai Zhang, Yang Yang, Yi Zhang & Song Zhao
Pages: 7813-7824
Published online: 19 Aug 2019
AbstractforOverexpressed PKMYT1 promotes tumor progression and associates with poor survival in esophageal squamous cell carcinoma | Full Text | References | PDF (3.1 MB) | EPUB
  • 139 Views
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Article
Radiomic signature: a non-invasive biomarker for discriminating invasive and non-invasive cases of lung adenocarcinoma
Bin Yang, Lili Guo, Guangming Lu, Wenli Shan, Lizhen Duan & Shaofeng Duan
Pages: 7825-7834
Published online: 19 Aug 2019
AbstractforRadiomic signature: a non-invasive biomarker for discriminating invasive and non-invasive cases of lung adenocarcinoma | Full Text | References | PDF (2.5 MB) | EPUB
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Article
Low expression of ZMYND8 correlates with aggressive features and poor prognosis in nasopharyngeal carcinoma
Jiewei Chen, Jun Liu, Xiaoting Chen, Yong Li, Zizi Li, Chengchao Shen, Keming Chen & Xinke Zhang
Pages: 7835-7843
Published online: 21 Aug 2019
AbstractforLow expression of ZMYND8 correlates with aggressive features and poor prognosis in nasopharyngeal carcinoma | Full Text | References | PDF (1.6 MB) | EPUB
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Article
Programmed cell death 4 (PDCD4) as a novel prognostic marker for papillary thyroid carcinoma
Francesca Galuppini, Matteo Fassan, Loris Bertazza, Susi Barollo, Luciano Cascione, Sara Watutantrige-Fernando, Vanni Lazzarin, Paolo Simonato, Federica Vianello, Massimo Rugge, Caterina Mian & Gianmaria Pennelli
Pages: 7845-7855
Published online: 20 Aug 2019
AbstractforProgrammed cell death 4 (PDCD4) as a novel prognostic marker for papillary thyroid carcinoma | Full Text | References | PDF (2.7 MB) | EPUB
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Article
Differentiation of chronic mass-forming pancreatitis from pancreatic ductal adenocarcinoma using contrast-enhanced computed tomography
Shuai Ren, Xiao Chen, Wenjing Cui, Rong Chen, Kai Guo, Huifeng Zhang, Shuai Chen & Zhongqiu Wang
Pages: 7857-7866
Published online: 20 Aug 2019
AbstractforDifferentiation of chronic mass-forming pancreatitis from pancreatic ductal adenocarcinoma using contrast-enhanced computed tomography | Full Text | References | PDF (2.1 MB) | EPUB
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Article
Comprehensive assessment of HER2 alteration in a colorectal cancer cohort: from next-generation sequencing to clinical significance
Yu-Min Yeh, Chun-Hui Lee, Shang-Hung Chen, Chung-Ta Lee, Yi-Lin Chen, Bo-Wen Lin, Shao-Chieh Lin, Ren-Hao Chan, Jenq-Chang Lee, Meng-Ru Shen & Peng-Chan Lin
Pages: 7867-7875
Published online: 20 Aug 2019
AbstractforComprehensive assessment of HER2 alteration in a colorectal cancer cohort: from next-generation sequencing to clinical significance | Full Text | References | PDF (3.1 MB) | EPUB
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Article
EIF3B is associated with poor outcomes in gastric cancer patients and promotes cancer progression via the PI3K/AKT/mTOR signaling pathway
Lin Wang, Xianzi Wen, Fengming Luan, Tao Fu, Chao Gao, Hong Du, Ting Guo, Jing Han, Longtao Huangfu, Xiaojing Cheng & Jiafu Ji
Pages: 7877-7891
Published online: 21 Aug 2019
AbstractforEIF3B is associated with poor outcomes in gastric cancer patients and promotes cancer progression via the PI3K/AKT/mTOR signaling pathway | Full Text | References | PDF (3.9 MB) | EPUB
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Article
Evaluating vandetanib in the treatment of medullary thyroid cancer: patient-reported outcomes
Poupak Fallahi, Silvia Martina Ferrari, Giusy Elia, Francesca Ragusa, Sabrina Rosaria Paparo, Ilaria Ruffilli, Armando Patrizio, Gabriele Materazzi & Alessandro Antonelli
Pages: 7893-7907
Published online: 21 Aug 2019
AbstractforEvaluating vandetanib in the treatment of medullary thyroid cancer: patient-reported outcomes | Full Text | References | PDF (365.1 KB) | EPUB
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Article
Downregulation of HDGF inhibits the tumorigenesis of bladder cancer cells by inactivating the PI3K-AKT signaling pathway
Cong Zhang, Xiangping Chang, Dongshan Chen, Feilong Yang, Zeyan Li, Dawei Li, Nengwang Yu, Lei Yan, Hainan Liu & Zhonghua Xu
Pages: 7909-7923
Published online: 22 Aug 2019
AbstractforDownregulation of HDGF inhibits the tumorigenesis of bladder cancer cells by inactivating the PI3K-AKT signaling pathway | Full Text | References | PDF (6 MB) | EPUB
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Article
Dynamic changes in T-cell subsets and C-reactive protein after radiation therapy in lung cancer patients and correlation with symptomatic radiation pneumonitis treated with steroid therapy
Lu Bai, Bao-Sen Zhou & Yu-Xia Zhao
Pages: 7925-7931
Published online: 22 Aug 2019
AbstractforDynamic changes in T-cell subsets and C-reactive protein after radiation therapy in lung cancer patients and correlation with symptomatic radiation pneumonitis treated with steroid therapy | Full Text | References | PDF (241.6 KB) | EPUB
  • 70 Views
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Article
Protective autophagy or autophagic death: effects of BEZ235 on chronic myelogenous leukemia
Pengliang Xin, Wenqian Xu, Xiongpeng Zhu, Chuntuan Li, Yan Zheng, Tingjin Zheng, Wenzhao Cheng & Qunyi Peng
Pages: 7933-7951
Published online: 22 Aug 2019
AbstractforProtective autophagy or autophagic death: effects of BEZ235 on chronic myelogenous leukemia | Full Text | References | PDF (7.2 MB) | EPUB
  • 50 Views
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Article
Antibiotic therapy augments the efficacy of gemcitabine-containing regimens for advanced cancer: a retrospective study
Hiroo Imai, Ken Saijo, Keigo Komine, Yasufumi Otsuki, Kota Ohuchi, Yuko Sato, Akira Okita, Masahiro Takahashi, Shin Takahashi, Hidekazu Shirota, Masanobu Takahashi & Chikashi Ishioka
Pages: 7953-7965
Published online: 22 Aug 2019
AbstractforAntibiotic therapy augments the efficacy of gemcitabine-containing regimens for advanced cancer: a retrospective study | Full Text | References | PDF (448.1 KB) | EPUB
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Article
MicroRNA-195 as a prognostic factor for cancer survival outcome in China: a meta-analysis
Ni Wang, Yang Cao, Xianxiu Ge, Junjie Nie, Yang Yu, Quanpeng Li, Fei Wang & Lin Miao
Pages: 7967-7979
Published online: 22 Aug 2019
AbstractforMicroRNA-195 as a prognostic factor for cancer survival outcome in China: a meta-analysis | Full Text | References | PDF (3.9 MB) | EPUB
  • 59 Views
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Article
The prognostic value of pretreatment inflammatory biomarkers in primary angiosarcoma
Manni Wang, Shuang Wu, An Tong, Xiwei Cui & Xuelei Ma
Pages: 7981-7989
Published online: 22 Aug 2019
AbstractforThe prognostic value of pretreatment inflammatory biomarkers in primary angiosarcoma | Full Text | References | PDF (992.8 KB) | EPUB
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Article
Skin lesions in chronic myeloid leukemia patients during dasatinib treatment
Francesco Tarantini, Luisa Anelli, Giuseppe Ingravallo, Immacolata Attolico, Antonella Zagaria, Antonella Russo Rossi, Lucia Lospalluti, Tamara Bufano, Giovanni Zanframundo, Eugenio Maiorano, Giorgina Specchia & Francesco Albano
Pages: 7991-7996
Published online: 26 Aug 2019
AbstractforSkin lesions in chronic myeloid leukemia patients during dasatinib treatment | Full Text | References | PDF (975.6 KB) | EPUB
  • 79 Views
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Article
High preoperative serum prealbumin predicts long-term survival in resected esophageal squamous cell cancer
Jun Wei, Ming Jin, Yingjie Shao, Zhonghua Ning & Jin Huang
Pages: 7997-8003
Published online: 26 Aug 2019
AbstractforHigh preoperative serum prealbumin predicts long-term survival in resected esophageal squamous cell cancer | Full Text | References | PDF (637.3 KB) | EPUB
  • 59 Views
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Article
RETRACTED ARTICLE: iNOS is associated with tumorigenicity as an independent prognosticator in human intrahepatic cholangiocarcinoma
Sulai Liu, Jinqiong Jiang, Linsheng Huang, Yu Jiang, Nanhui Yu, Xiehong Liu, Yuan Lv, Hao Li, Lianhong Zou, Chuang Peng, Xing Yu & Bo Jiang
Pages: 8005-8022
Published online: 26 Aug 2019
AbstractforRETRACTED ARTICLE: iNOS is associated with tumorigenicity as an independent prognosticator in human intrahepatic cholangiocarcinoma | PDF (4.1 MB)
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Article
Knockdown of EBV-encoded circRNA circRPMS1 suppresses nasopharyngeal carcinoma cell proliferation and metastasis through sponging multiple miRNAs
Qianwen Liu, Mingxia Shuai & Yong Xia
Pages: 8023-8031
Published online: 27 Aug 2019
AbstractforKnockdown of EBV-encoded circRNA circRPMS1 suppresses nasopharyngeal carcinoma cell proliferation and metastasis through sponging multiple miRNAs | Full Text | References | PDF (4.8 MB) | EPUB
  • 114 Views
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Article
Factors associated with human papillomavirus infection – findings from a cervical cancer screening program for female employees in Beijing
Hui-xia Yang, Yu Zhong, Wei-hua Lv & Hong Yu
Pages: 8033-8041
Published online: 28 Aug 2019
AbstractforFactors associated with human papillomavirus infection – findings from a cervical cancer screening program for female employees in Beijing | Full Text | References | PDF (842.7 KB) | EPUB
  • 87 Views
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Article
Do early HER2-overexpression breast cancer patients benefit from undergoing neoadjuvant trastuzumab and mastectomy? A meta-analysis
Lin He, Qian Wu, Jing Xiong, Zhumin Su, Biyuan Zhang & Yuhua Song
Pages: 8043-8054
Published online: 29 Aug 2019
AbstractforDo early HER2-overexpression breast cancer patients benefit from undergoing neoadjuvant trastuzumab and mastectomy? A meta-analysis | Full Text | References | PDF (2.7 MB) | EPUB
  • 64 Views
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Original Research

Article
Long noncoding RNA MIR31HG abrogates the availability of tumor suppressor microRNA-361 for the growth of osteosarcoma
Yongjie Sun, Xinghao Jia, Mingxing Wang & Yiqi Deng
Pages: 8055-8064
Published online: 30 Aug 2019
AbstractforLong noncoding RNA MIR31HG abrogates the availability of tumor suppressor microRNA-361 for the growth of osteosarcoma | Full Text | References | PDF (2.3 MB) | EPUB
  • 63 Views
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Article
A prospective study on urine alkalization with an oral regimen consisting of sodium bicarbonate and acetazolamide in patients receiving high-dose methotrexate
Daniel R Reed, Eric J Pierce, Jeremy M Sen & Michael K Keng
Pages: 8065-8072
Published online: 30 Aug 2019
AbstractforA prospective study on urine alkalization with an oral regimen consisting of sodium bicarbonate and acetazolamide in patients receiving high-dose methotrexate | Full Text | References | PDF (230.2 KB) | EPUB
  • 166 Views
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Review

Article
Enasidenib in acute myeloid leukemia: clinical development and perspectives on treatment
Daniel R Reed, Ramey Z Elsarrag, Amy L Morris & Michael K Keng
Pages: 8073-8080
Published online: 30 Aug 2019
AbstractforEnasidenib in acute myeloid leukemia: clinical development and perspectives on treatment | Full Text | References | PDF (494 KB) | EPUB
  • 124 Views
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Article
The role of low density lipoprotein receptor-related protein 11 as a tumor promoter in cervical cancer
Ying Wang, Sai Han, Xuewu You, Xuejiao Shi, Lu Liu, Yu Sun, Yana Ma, Qiuhong Qian, Hongli Liu, Baoxia Cui & Youzhong Zhang
Pages: 8081-8093
Published online: 30 Aug 2019
AbstractforThe role of low density lipoprotein receptor-related protein 11 as a tumor promoter in cervical cancer | Full Text | References | PDF (11.1 MB) | EPUB
  • 80 Views
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Review

Article
Asunercept as an innovative therapeutic approach for recurrent glioblastoma and other malignancies
Andriy Krendyukov & Christian Gieffers
Pages: 8095-8100
Published online: 02 Sep 2019
AbstractforAsunercept as an innovative therapeutic approach for recurrent glioblastoma and other malignancies | Full Text | References | PDF (224.4 KB) | EPUB
  • 51 Views
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Article
Preoperative Cachexia predicts poor outcomes in young rather than elderly gastric cancer patients: a prospective study
Xiaodong Chen, Yunpeng Zeng, Yunshi Huang, Jingxuan Xu, Weiyang Meng, Xiang Wang, Ce Zhu, Guanbao Zhu, Chenchen Mao & Xian Shen
Pages: 8101-8110
Published online: 02 Sep 2019
AbstractforPreoperative Cachexia predicts poor outcomes in young rather than elderly gastric cancer patients: a prospective study | Full Text | References | PDF (1.1 MB) | EPUB
  • 77 Views
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Article
ERRα is an aggressive factor in lung adenocarcinoma indicating poor prognostic outcomes
Ping Li, Jian Wang, Desheng Wu, Xiaohu Ren, Wen Wu, Ran Zuo, Qingbo Zeng, Bingyu Wang, Xi He, Jianhui Yuan & Ni Xie
Pages: 8111-8123
Published online: 02 Sep 2019
AbstractforERRα is an aggressive factor in lung adenocarcinoma indicating poor prognostic outcomes | Full Text | References | PDF (3.3 MB) | EPUB
  • 84 Views
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Article
RETRACTED ARTICLE: Effect of SMYD3 on biological behavior and H3K4 methylation in bladder cancer
Xiang Wu, Qingjiang Xu, Pingzhou Chen, Chenbo Yu, Liefu Ye, Chen Huang & Tao Li
Pages: 8125-8133
Published online: 02 Sep 2019
AbstractforRETRACTED ARTICLE: Effect of SMYD3 on biological behavior and H3K4 methylation in bladder cancer | PDF (2.4 MB)
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Article
Magnesemia: an independent risk factor of hypocalcemia after thyroidectomy
Wenlong Wang, Chaoyang Meng, Qianhui Ouyang, Jing Xie & Xinying Li
Pages: 8135-8144
Published online: 03 Sep 2019
AbstractforMagnesemia: an independent risk factor of hypocalcemia after thyroidectomy | Full Text | References | PDF (266.7 KB) | EPUB
  • 71 Views
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Article
Recent insights into breast cancer incidence trends among four Asian countries using age-period-cohort model
Sumaira Mubarik, Saima Shakil Malik, Zhenkun Wang, Chunhui Li, Muhammad Fawad & Chuanhua Yu
Pages: 8145-8155
Published online: 03 Sep 2019
AbstractforRecent insights into breast cancer incidence trends among four Asian countries using age-period-cohort model | Full Text | References | PDF (2.2 MB) | EPUB
  • 347 Views
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Article
Clinical study of nimotuzumab combined with concurrent radiochemotherapy for treatment of locally advanced cervical cancer
Wenli Chen, Tao Li, Jian Wang, Long Liang, Dandan Huang, Gaoshu Yan, Ye Tian, Xiaoli Zhang & Wei Zhang
Pages: 8157-8165
Published online: 03 Sep 2019
AbstractforClinical study of nimotuzumab combined with concurrent radiochemotherapy for treatment of locally advanced cervical cancer | Full Text | References | PDF (1.4 MB) | EPUB
  • 116 Views
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Article
Overexpression of HOXC6 promotes cell proliferation and migration via MAPK signaling and predicts a poor prognosis in glioblastoma
PengYu Yang, Wei Kang, YaWen Pan, XianJun Zhao & Lei Duan
Pages: 8167-8179
Published online: 03 Sep 2019
AbstractforOverexpression of HOXC6 promotes cell proliferation and migration via MAPK signaling and predicts a poor prognosis in glioblastoma | Full Text | References | PDF (3.1 MB) | EPUB
  • 72 Views
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Review

Article
The prognostic value of pretreatment Glasgow Prognostic Score in patients with esophageal cancer: a meta-analysis
Yan Wang, Pengfei Li, Jue Li, Yutian Lai, Kun Zhou, Xin Wang & Guowei Che
Pages: 8181-8190
Published online: 04 Sep 2019
AbstractforThe prognostic value of pretreatment Glasgow Prognostic Score in patients with esophageal cancer: a meta-analysis | Full Text | References | PDF (1.8 MB) | EPUB
  • 67 Views
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Original Research

Article
Elevated levels of pre-treatment lactate dehydrogenase are an unfavorable predictor factor in patients with EML4-ALK rearrangement non-small cell lung cancer treated with crizotinib
Hongge Liang, Di Ma, Yan Xu, Jing Zhao, Minjiang Chen, Xiaoyan Liu, Wei Zhong, Junling Li & Mengzhao Wang
Pages: 8191-8200
Published online: 05 Sep 2019
AbstractforElevated levels of pre-treatment lactate dehydrogenase are an unfavorable predictor factor in patients with EML4-ALK rearrangement non-small cell lung cancer treated with crizotinib | Full Text | References | PDF (1.1 MB) | EPUB
  • 53 Views
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Article
Correlation of body composition by computerized tomography and metabolic parameters with survival of nivolumab-treated lung cancer patients
Valentina Magri, Teodor Gottfried, Mattia Di Segni, Damien Urban, Michael Peled, Sameh Daher, Ronen Stoff, Jair Bar & Amir Onn
Pages: 8201-8207
Published online: 05 Sep 2019
AbstractforCorrelation of body composition by computerized tomography and metabolic parameters with survival of nivolumab-treated lung cancer patients | Full Text | References | PDF (926.6 KB) | EPUB
  • 83 Views
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Article
Differential gene expression identifies KRT7 and MUC1 as potential metastasis-specific targets in sarcoma
Long Jiang, Bhairavi Tolani, Che-Chung Yeh, Yanying Fan, Joseph A Reza, Andrew E Horvai, Endi Xia, Johannes R Kratz, David M Jablons & Michael J Mann
Pages: 8209-8218
Published online: 09 Sep 2019
AbstractforDifferential gene expression identifies KRT7 and MUC1 as potential metastasis-specific targets in sarcoma | Full Text | References | PDF (4.7 MB) | EPUB
  • 85 Views
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Article
Increased expression of heat shock protein (HSP) 10 and HSP70 correlates with poor prognosis of nasopharyngeal carcinoma
Juan Feng, Yuting Zhan, Yuting Zhang, Hongmei Zheng, Weiyuan Wang & Songqing Fan
Pages: 8219-8227
Published online: 06 Sep 2019
AbstractforIncreased expression of heat shock protein (HSP) 10 and HSP70 correlates with poor prognosis of nasopharyngeal carcinoma | Full Text | References | PDF (1.3 MB) | EPUB
  • 72 Views
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Article
The synergistic antileukemic effects of eltrombopag and decitabine in myeloid leukemia cells
Mingyue Shi, Fangfang Xu, Xiawan Yang, Yanliang Bai, Junwei Niu, Emmanuel Kwateng Drokow, Mingyi Chen, Yuqing Chen & Kai Sun
Pages: 8229-8238
Published online: 06 Sep 2019
AbstractforThe synergistic antileukemic effects of eltrombopag and decitabine in myeloid leukemia cells | Full Text | References | PDF (3 MB) | EPUB
  • 72 Views
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Article
Added value of histogram analysis of apparent diffusion coefficient maps for differentiating triple-negative breast cancer from other subtypes of breast cancer on standard MRI
Hong-Li Liu, Min Zong, Han Wei, Cong Wang, Jian-Juan Lou, Si-Qi Wang, Qi-Gui Zou & Yan-Ni Jiang
Pages: 8239-8247
Published online: 06 Sep 2019
AbstractforAdded value of histogram analysis of apparent diffusion coefficient maps for differentiating triple-negative breast cancer from other subtypes of breast cancer on standard MRI | Full Text | References | PDF (1.2 MB) | EPUB
  • 84 Views
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Article
Adverse effect of laparoscopic radical hysterectomy depends on tumor size in patients with cervical cancer
Ting Wen Yi Hu, Xiu Ming, Hao Zheng Yan & Zheng Yu Li
Pages: 8249-8255
Published online: 09 Sep 2019
AbstractforAdverse effect of laparoscopic radical hysterectomy depends on tumor size in patients with cervical cancer | Full Text | References | PDF (971.5 KB) | EPUB
  • 61 Views
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Review

Review Article
The relationship between pancreatic cancer and type 2 diabetes: cause and consequence
Yan Li, Xiaohui Bian, Shuyi Wei, Meizhi He & Yuelian Yang
Pages: 8257-8268
Published online: 09 Sep 2019
AbstractforThe relationship between pancreatic cancer and type 2 diabetes: cause and consequence | Full Text | References | PDF (1.1 MB) | EPUB
  • 250 Views
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Original Research

Article
Neutrophil-to-lymphocyte ratio predicts the prognosis of stage II nasopharyngeal carcinoma
Xin-Bin Pan, Shi-Ting Huang & Xiao-Dong Zhu
Pages: 8269-8275
Published online: 09 Sep 2019
AbstractforNeutrophil-to-lymphocyte ratio predicts the prognosis of stage II nasopharyngeal carcinoma | Full Text | References | PDF (534.1 KB) | EPUB
  • 55 Views
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Article
Gemcitabine, cisplatin, prednisone, and thalidomide for relapse and refractory peripheral T-cell lymphoma: a retrospective study from China
Xiangli Liu, YuFeng Shang, Ling Li, Xudong Zhang, Zhaoming Li & Mingzhi Zhang
Pages: 8277-8284
Published online: 09 Sep 2019
AbstractforGemcitabine, cisplatin, prednisone, and thalidomide for relapse and refractory peripheral T-cell lymphoma: a retrospective study from China | Full Text | References | PDF (660.5 KB) | EPUB
  • 62 Views
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Article
Clinical results of intensity-modulated radiotherapy for 250 patients with cervical and upper thoracic esophageal carcinoma
Jiaqi Zhang, Wencheng Zhang, Baozhong Zhang, Dong Qian, Xiaoxia Li, Hualei Zhang, Qi Wang, Lujun Zhao, Qingsong Pang & Ping Wang
Pages: 8285-8294
Published online: 10 Sep 2019
AbstractforClinical results of intensity-modulated radiotherapy for 250 patients with cervical and upper thoracic esophageal carcinoma | Full Text | References | PDF (503 KB) | EPUB
  • 65 Views
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Article
Analysis of the efficacy and safety of bortezomib for treating newly diagnosed multiple myeloma through different administration methods
Hong-Mei Zhang, Xi-Yang Liu, Yu-Zhang Liu, Li-Na Liu, Quan-De Lin, Yong-Ping Song & Bai-Jun Fang
Pages: 8295-8302
Published online: 10 Sep 2019
AbstractforAnalysis of the efficacy and safety of bortezomib for treating newly diagnosed multiple myeloma through different administration methods | Full Text | References | PDF (1.3 MB) | EPUB
  • 55 Views
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Article
12-lipoxygenase promotes tumor progress by TGF-β1-mediated epithelial to mesenchymal transition and predicts poor prognosis in esophageal squamous cell carcinoma
Yan Qu, Zhihua Wen, Si Mi, Pengxiang Chen, Jianbo Wang, Yibin Jia & Yufeng Cheng
Pages: 8303-8313
Published online: 11 Sep 2019
Abstractfor12-lipoxygenase promotes tumor progress by TGF-β1-mediated epithelial to mesenchymal transition and predicts poor prognosis in esophageal squamous cell carcinoma | Full Text | References | PDF (3.1 MB) | EPUB
  • 56 Views
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Article
Predictive And Prognostic Value Of Hepatic Steatosis In Conversion Therapy For Colorectal Liver-limited Metastases: A Propensity Score Matching Analysis
Mi Jian, Wenju Chang, Li Ren, Tianyu Liu, Yijiao Chen, Ye Wei, Qi Lin, Jianmin Xu & Xinyu Qin
Pages: 8315-8326
Published online: 11 Sep 2019
AbstractforPredictive And Prognostic Value Of Hepatic Steatosis In Conversion Therapy For Colorectal Liver-limited Metastases: A Propensity Score Matching Analysis | Full Text | References | PDF (1.9 MB) | EPUB
  • 67 Views
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Review

Article
Carbon ion and proton beam irradiation of a normal human TK6 lymphoblastoid cell line within a magnetic field of 1.0 tesla
B Yudhistiara, KJ Weber, PE Huber, A Ruehle, S Brons, P Haering, J Debus & H Hauswald
Pages: 8327-8335
Published online: 12 Sep 2019
AbstractforCarbon ion and proton beam irradiation of a normal human TK6 lymphoblastoid cell line within a magnetic field of 1.0 tesla | Full Text | References | PDF (2.3 MB) | EPUB
  • 58 Views
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Original Research

Article
Spatial heterogeneity of KRAS mutations in colorectal cancers in northern France
Anthony Turpin, Michael Genin, Mohamed Hebbar, Florent Occelli, Caroline Lanier, Francis Vasseur, Clotilde Descarpentries, Diane Pannier & Anne Ploquin
Pages: 8337-8344
Published online: 13 Sep 2019
AbstractforSpatial heterogeneity of KRAS mutations in colorectal cancers in northern France | Full Text | References | PDF (1.1 MB) | EPUB
  • 64 Views
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Article
Histone deacetylase inhibitors reinforce the phenotypical markers of breast epithelial or mesenchymal cancer cells but inhibit their migratory properties
Anna Wawruszak, Ewelina Gumbarewicz, Estera Okon, Witold Jeleniewicz, Jakub Czapinski, Marta Halasa, Karolina Okla, Jolanta Smok-Kalwat, Artur Bocian, Adolfo Rivero-Muller & Andrzej Stepulak
Pages: 8345-8358
Published online: 13 Sep 2019
AbstractforHistone deacetylase inhibitors reinforce the phenotypical markers of breast epithelial or mesenchymal cancer cells but inhibit their migratory properties | Full Text | References | PDF (12.5 MB) | EPUB
  • 86 Views
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Article
UBE2T promotes proliferation via G2/M checkpoint in hepatocellular carcinoma
Li-Li Liu, Ji-Min Zhu, Xiang-Nan Yu, Hai-Rong Zhu, Xuan Shi, Enkhnaran Bilegsaikhan, Hong-Ying Guo, Jian Wu & Xi-Zhong Shen
Pages: 8359-8370
Published online: 13 Sep 2019
AbstractforUBE2T promotes proliferation via G2/M checkpoint in hepatocellular carcinoma | Full Text | References | PDF (6.5 MB) | EPUB
  • 91 Views
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Article
rhTPO combined with chemotherapy and G-CSF for autologous peripheral blood stem cells in patients with refractory/relapsed non-Hodgkin’s lymphoma
Jun Zhu, Si-Guo Hao, Jiong Hu, Jing-Li Zhuang, Chun Wang & Hai-Tao Bai
Pages: 8371-8377
Published online: 13 Sep 2019
AbstractforrhTPO combined with chemotherapy and G-CSF for autologous peripheral blood stem cells in patients with refractory/relapsed non-Hodgkin’s lymphoma | Full Text | References | PDF (232.4 KB) | EPUB
  • 67 Views
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Article
Risk factors of catheter-related thrombosis in early-stage breast cancer patients: a single-center retrospective study
Luyuan Tan, Ya Sun, Liling Zhu, Xin Lei, Dongya Liang, Nanyan Rao, Fengxi Su, Kai Chen & Shunrong Li
Pages: 8379-8389
Published online: 13 Sep 2019
AbstractforRisk factors of catheter-related thrombosis in early-stage breast cancer patients: a single-center retrospective study | Full Text | References | PDF (522.7 KB) | EPUB
  • 98 Views
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Article
Berzosertib (VE-822) inhibits gastric cancer cell proliferation via base excision repair system
Fubiao Ni, Hengjie Tang, Cheng Wang, Zixiang Wang, Fangyi Yu, Bicheng Chen & Linxiao Sun
Pages: 8391-8405
Published online: 13 Sep 2019
AbstractforBerzosertib (VE-822) inhibits gastric cancer cell proliferation via base excision repair system | Full Text | References | PDF (8.8 MB) | EPUB
  • 88 Views
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Review

Article
Mechanisms Underlying Therapeutic Effects Of Traditional Chinese Medicine On Gastric Cancer
Linjun Yang, Liqian Zhao, Tianni Zeng, Hong Chen, Jingjing Shao, Song Yang, Zheying Tao, Jingqin Yang, Tongke Chen, Xiaokun Lin, Xiwen Chen & Mosheng Tang
Pages: 8407-8418
Published online: 16 Sep 2019
AbstractforMechanisms Underlying Therapeutic Effects Of Traditional Chinese Medicine On Gastric Cancer | Full Text | References | PDF (1.3 MB) | EPUB
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Original Research

Article
RETRACTED ARTICLE: MicroRNA‑506 regulates apoptosis in retinoblastoma cells by targeting sirtuin 1
Zhidu Song, Hailiang Wang, Fangwei Zong, Chao Zhu & Ying Tao
Pages: 8419-8429
Published online: 16 Sep 2019
AbstractforRETRACTED ARTICLE: MicroRNA‑506 regulates apoptosis in retinoblastoma cells by targeting sirtuin 1 | PDF (3.7 MB)
  • 74 Views
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Review

Article
Characteristic And Novel Therapeutic Strategies Of Nasopharyngeal Carcinoma With Synchronous Metastasis
Wenjun Liao, Maolang Tian & Nianyong Chen
Pages: 8431-8442
Published online: 16 Sep 2019
AbstractforCharacteristic And Novel Therapeutic Strategies Of Nasopharyngeal Carcinoma With Synchronous Metastasis | Full Text | References | PDF (2.9 MB) | EPUB
  • 67 Views
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Original Research

Article
Anti-tumor effects of engineered mesenchymal stem cells in colon cancer model
Jianying Yang, Kui Lv, Junfeng Sun & Jianguo Guan
Pages: 8443-8450
Published online: 17 Sep 2019
AbstractforAnti-tumor effects of engineered mesenchymal stem cells in colon cancer model | Full Text | References | PDF (2.7 MB) | EPUB
  • 102 Views
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Article
The prognostic value of the lymphocyte-to-monocyte ratio for high-risk papillary thyroid carcinoma
Linlin Song, Jingqiang Zhu, Zhihui Li, Tao Wei, Rixiang Gong & Jianyong Lei
Pages: 8451-8462
Published online: 17 Sep 2019
AbstractforThe prognostic value of the lymphocyte-to-monocyte ratio for high-risk papillary thyroid carcinoma | Full Text | References | PDF (7 MB) | EPUB
  • 72 Views
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Article
Emodin sensitizes human pancreatic cancer cells to EGFR inhibitor through suppressing Stat3 signaling pathway
Zhaohong Wang, Hui Chen, Jingjing Chen, Zhong Hong, Yi Liao, Qiyu Zhang & Hongfei Tong
Pages: 8463-8473
Published online: 17 Sep 2019
AbstractforEmodin sensitizes human pancreatic cancer cells to EGFR inhibitor through suppressing Stat3 signaling pathway | Full Text | References | PDF (9 MB) | EPUB
  • 76 Views
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Article
Impact of antiviral therapy with nucleos(t)ide analog on survival of patients with HBV-related small hepatocellular carcinomas
Yanyan Wei, Yongxiang Yi, Chen Tao, Wei Ye & Wei Zhao
Pages: 8475-8486
Published online: 17 Sep 2019
AbstractforImpact of antiviral therapy with nucleos(t)ide analog on survival of patients with HBV-related small hepatocellular carcinomas | Full Text | References | PDF (784.6 KB) | EPUB
  • 64 Views
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Article
Long Noncoding RNA GAS5 Acts As A Tumor Suppressor In Laryngeal Squamous Cell Carcinoma Via miR-21
Kexing Lyu, Yang Xu, Huijun Yue, Yun Li, Jing Zhao, Lin Chen, Jianhui Wu, Xiaolin Zhu, Liping Chai, Chunwei Li, Weiping Wen & Wenbin Lei
Pages: 8487-8498
Published online: 17 Sep 2019
AbstractforLong Noncoding RNA GAS5 Acts As A Tumor Suppressor In Laryngeal Squamous Cell Carcinoma Via miR-21 | Full Text | References | PDF (5.9 MB) | EPUB
  • 73 Views
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Article
Quality of life of patients with proximal humerus metastasis treated with cement spacer
Wen Guo, Xin Gao, Dongsheng Wang, Tao Wang, Liang Tang, Yao Wang & Bin Liu
Pages: 8499-8506
Published online: 17 Sep 2019
AbstractforQuality of life of patients with proximal humerus metastasis treated with cement spacer | Full Text | References | PDF (1.1 MB) | EPUB
  • 61 Views
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Article
Clinicopathological features and outcomes of esophageal lesions containing a basal layer type squamous cell carcinoma component
Xiaoduan Zhuang, Zhenyu Chen, Jianqi Wang, Junsheng Chen, Xiaosheng Wu, Yadong Wang, Chudi Chen, Guoming Deng, Kai Qian & Yang Bai
Pages: 8507-8516
Published online: 18 Sep 2019
AbstractforClinicopathological features and outcomes of esophageal lesions containing a basal layer type squamous cell carcinoma component | Full Text | References | PDF (2.7 MB) | EPUB
  • 69 Views
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Article
Long noncoding RNA PVT1 promotes hepatoblastoma cell proliferation through activating STAT3
Zhenqin Luo & Peiguo Cao
Pages: 8517-8527
Published online: 20 Sep 2019
AbstractforLong noncoding RNA PVT1 promotes hepatoblastoma cell proliferation through activating STAT3 | Full Text | References | PDF (2.6 MB) | EPUB
  • 58 Views
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Methodology

Article
Beyond The T/C Ratio: Old And New Anticancer Activity Scores In Vivo
Paolo Ubezio
Pages: 8529-8538
Published online: 19 Sep 2019
AbstractforBeyond The T/C Ratio: Old And New Anticancer Activity Scores In Vivo | Full Text | References | PDF (1.5 MB) | EPUB
  • 72 Views
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Original Research

Article
Concurrent proton-pump inhibitors increase risk of death for lung cancer patients receiving 1st-line gefitinib treatment - a nationwide population-based study
Yu-Hung Fang, Yao-Hsu Yang, Meng-Jer Hsieh, Ming-Szu Hung & Yu-Ching Lin
Pages: 8539-8546
Published online: 19 Sep 2019
AbstractforConcurrent proton-pump inhibitors increase risk of death for lung cancer patients receiving 1st-line gefitinib treatment - a nationwide population-based study | Full Text | References | PDF (2 MB) | EPUB
  • 89 Views
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Article
ADAR1 may be involved in the proliferation of acute myeloid leukemia cells via regulation of the Wnt pathway
Han Xiao, Qian Cheng, Xinyu Wu, Yishu Tang, Jing Liu & Xin Li
Pages: 8547-8555
Published online: 20 Sep 2019
AbstractforADAR1 may be involved in the proliferation of acute myeloid leukemia cells via regulation of the Wnt pathway | Full Text | References | PDF (3.2 MB) | EPUB
  • 88 Views
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Article
Linc01278 inhibits the development of papillary thyroid carcinoma by regulating miR-376c-3p/DNM3 axis
Shaojian Lin, Langping Tan, Dingyuan Luo, Xinzhi Peng, Yue Zhu & Honghao Li
Pages: 8557-8569
Published online: 19 Sep 2019
AbstractforLinc01278 inhibits the development of papillary thyroid carcinoma by regulating miR-376c-3p/DNM3 axis | Full Text | References | PDF (9 MB) | EPUB
  • 58 Views
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Research Letter

Article
Atopobium vaginae And Porphyromonas somerae Induce Proinflammatory Cytokines Expression In Endometrial Cells: A Possible Implication For Endometrial Cancer?
Elisabetta Caselli, Irene Soffritti, Maria D’Accolti, Isabella Piva, Pantaleo Greco & Gloria Bonaccorsi
Pages: 8571-8575
Published online: 23 Sep 2019
First Page PreviewforAtopobium vaginae And Porphyromonas somerae Induce Proinflammatory Cytokines Expression In Endometrial Cells: A Possible Implication For Endometrial Cancer? | Full Text | References | PDF (2.1 MB) | EPUB
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Original Research

Article
Clinical features, treatment and outcomes of colorectal mucosa-associated lymphoid tissue (MALT) lymphoma: literature reviews published in English between 1993 and 2017
Jae Hee Won, Sung Min Kim, Jong Wan Kim, Jun Ho Park & Jeong Yeon Kim
Pages: 8577-8587
Published online: 20 Sep 2019
AbstractforClinical features, treatment and outcomes of colorectal mucosa-associated lymphoid tissue (MALT) lymphoma: literature reviews published in English between 1993 and 2017 | Full Text | References | PDF (1.1 MB) | EPUB
  • 111 Views
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Article
Epigenetic regulation of IncRNA KCNKI5-ASI in gastric cancer
Haiyan Zhang, Zhuo Zhang & Dayu Wang
Pages: 8589-8602
Published online: 20 Sep 2019
AbstractforEpigenetic regulation of IncRNA KCNKI5-ASI in gastric cancer | Full Text | References | PDF (5.3 MB) | EPUB
  • 68 Views
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Retraction

Retraction
Long Noncoding RNA LINC00511 Promotes Cell Growth And Invasion In Triple-Negative Breast Cancer By Interacting With Snail [Retraction]
Page: 8603
Published online: 23 Sep 2019
CitationforLong Noncoding RNA LINC00511 Promotes Cell Growth And Invasion In Triple-Negative Breast Cancer By Interacting With Snail [Retraction] | Full Text | PDF (149.8 KB) | EPUB
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Retraction
miR-140-5p Alleviates The Aggressive Progression Of Wilms’ Tumor Through Directly Targeting TGFBR I Gene [Retraction]
Page: 8605
Published online: 23 Sep 2019
CitationformiR-140-5p Alleviates The Aggressive Progression Of Wilms’ Tumor Through Directly Targeting TGFBR I Gene [Retraction] | Full Text | PDF (152.5 KB) | EPUB
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Original Research

Article
Downregulated MCOLN1 Attenuates The Progression Of Non-Small-Cell Lung Cancer By Inhibiting Lysosome-Autophagy
Chuntong Yin, Han Zhang, Xin Liu, Haiying Zhang, Yue Zhang, Xue Bai, Lei Wang, Huimin Li, Xia Li, Shuqian Zhang, Linyou Zhang & Yong Zhang
Pages: 8607-8617
Published online: 23 Sep 2019
AbstractforDownregulated MCOLN1 Attenuates The Progression Of Non-Small-Cell Lung Cancer By Inhibiting Lysosome-Autophagy | Full Text | References | PDF (6.3 MB) | EPUB
  • 69 Views
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Article
A New Regulatory Mechanism Between P53 And YAP Crosstalk By SIRT1 Mediated Deacetylation To Regulate Cell Cycle And Apoptosis In A549 Cell Lines
Fang Yuan, Jinliang Wang, Ruixin Li, Xiao Zhao, Yuxuan Zhang, Biao Liu, Yonghong Lei & Yi Hu
Pages: 8619-8633
Published online: 23 Sep 2019
AbstractforA New Regulatory Mechanism Between P53 And YAP Crosstalk By SIRT1 Mediated Deacetylation To Regulate Cell Cycle And Apoptosis In A549 Cell Lines | Full Text | References | PDF (9.1 MB) | EPUB
  • 109 Views
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Article
Columbamine suppresses the proliferation and malignization of colon cancer cells via abolishing Wnt/β-catenin signaling pathway
Changjiang Lei, Yao Yao, Bin Shen, Junru Liu, Qingyun Pan, Ning Liu, Lei Li, Jianbin Huang, Zhixiong Long & Liwei Shao
Pages: 8635-8645
Published online: 23 Sep 2019
AbstractforColumbamine suppresses the proliferation and malignization of colon cancer cells via abolishing Wnt/β-catenin signaling pathway | Full Text | References | PDF (2.9 MB) | EPUB
  • 90 Views
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Article
Comparison of outcomes of complete mesocolic excision with conventional radical resection performed by laparoscopic approach for right colon cancer
Manzhao Ouyang, Zhentao Luo, Jinhao Wu, Weijie Zhang, Shibin Tang, Yan Lu, Weixian Hu & Xueqing Yao
Pages: 8647-8656
Published online: 25 Sep 2019
AbstractforComparison of outcomes of complete mesocolic excision with conventional radical resection performed by laparoscopic approach for right colon cancer | Full Text | References | PDF (1.9 MB) | EPUB
  • 88 Views
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Article
Pre-treatment inflammatory biomarkers predict early treatment response and favorable survival in patients with metastatic colorectal cancer who underwent first line cetuximab plus chemotherapy
Jinling Jiang, Tao Ma, Wenqi Xi, Chen Yang, Junwei Wu, Chenfei Zhou, Nan Wang, Zhenggang Zhu & Jun Zhang
Pages: 8657-8668
Published online: 24 Sep 2019
AbstractforPre-treatment inflammatory biomarkers predict early treatment response and favorable survival in patients with metastatic colorectal cancer who underwent first line cetuximab plus chemotherapy | Full Text | References | PDF (4 MB) | EPUB
  • 99 Views
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Review

Article
Common molecular markers between circulating tumor cells and blood exosomes in colorectal cancer: a systematic and analytical review
Somayeh Vafaei, Fahimeh Fattahi, Marzieh Ebrahimi, Leila Janani, Ahmad Shariftabrizi & Zahra Madjd
Pages: 8669-8698
Published online: 25 Sep 2019
AbstractforCommon molecular markers between circulating tumor cells and blood exosomes in colorectal cancer: a systematic and analytical review | Full Text | References | PDF (3.8 MB) | EPUB
  • 178 Views
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Original Research

Article
Long non-coding RNA TUG1-mediated down-regulation of KLF4 contributes to metastasis and the epithelial-to-mesenchymal transition of colorectal cancer by miR-153-1
Hongjin Shao, Dianbo Dong & Feng Shao
Pages: 8699-8710
Published online: 24 Sep 2019
AbstractforLong non-coding RNA TUG1-mediated down-regulation of KLF4 contributes to metastasis and the epithelial-to-mesenchymal transition of colorectal cancer by miR-153-1 | Full Text | References | PDF (5.2 MB) | EPUB
  • 73 Views
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Article
Bortezomib sensitivity is tissue dependent and high expression of the 20S proteasome precludes good response in malignant pleural mesothelioma
Robert Fred Henry Walter, Saskia Roxanne Sydow, Erika Berg, Jens Kollmeier, Daniel Christian Christoph, Sandra Christoph, Wilfried Ernst Erich Eberhardt, Thomas Mairinger, Jeremias Wohlschlaeger, Kurt Werner Schmid & Fabian Dominik Mairinger
Pages: 8711-8720
Published online: 24 Sep 2019
AbstractforBortezomib sensitivity is tissue dependent and high expression of the 20S proteasome precludes good response in malignant pleural mesothelioma | Full Text | References | PDF (2.9 MB) | EPUB
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Review

Article
Prevalence, Risk Factors And Location Of Skip Metastasis In Papillary Thyroid Carcinoma: A Systematic Review And Meta-Analysis
Yuxuan Qiu, Yuan Fei, Jingyan Liu, Chang Liu, Xin He, Ning Zhu, Wan-jun Zhao & Jing-qiang Zhu
Pages: 8721-8730
Published online: 25 Sep 2019
AbstractforPrevalence, Risk Factors And Location Of Skip Metastasis In Papillary Thyroid Carcinoma: A Systematic Review And Meta-Analysis | Full Text | References | PDF (3.4 MB) | EPUB
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Original Research

Article
Development and validation of CT imaging–based preoperative nomogram in the prediction of unfavorable high-grade small renal masses
Hui Xie, Gang Li, Kangkang Liu, Zhun Wang, Zhiqun Shang, Zihao Liu, Zhilei Xiong, Changyi Quan & Yuanjie Niu
Pages: 8731-8741
Published online: 25 Sep 2019
AbstractforDevelopment and validation of CT imaging–based preoperative nomogram in the prediction of unfavorable high-grade small renal masses | Full Text | References | PDF (6.1 MB) | EPUB
  • 56 Views
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Article
Silencing of TAZ inhibits the motility of hepatocellular carcinoma cells through autophagy induction
Wei Zhou, Jiachun Weng, Keyan Wu, Xiao Xu, Hui Wang, Jing Zhang, Chengxue Zhao, Jie Yang, Yu Zhang & Weigan Shen
Pages: 8743-8753
Published online: 26 Sep 2019
AbstractforSilencing of TAZ inhibits the motility of hepatocellular carcinoma cells through autophagy induction | Full Text | References | PDF (27.2 MB) | EPUB
  • 52 Views
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Review

Article
A Meta-Analysis And Systematic Review Of Accuracy Of Endoscopic Ultrasound For N Staging Of Gastric Cancers
Jiafei Chen, Chaoyang Zhou, Min He, Zhiming Zhen, Jie Wang & Xiaofei Hu
Pages: 8755-8764
Published online: 27 Sep 2019
AbstractforA Meta-Analysis And Systematic Review Of Accuracy Of Endoscopic Ultrasound For N Staging Of Gastric Cancers | Full Text | References | PDF (4 MB) | EPUB
  • 72 Views
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Original Research

Article
Preoperative Hyponatremia And Hypocalcemia Predict Poor Prognosis In Elderly Gastric Cancer Patients
Jingxuan Xu, Xiaodong Chen, Xiang Wang, Ce Zhu, Yuanbo Hu, Xinxin Yang, Chongyong Xu & Xian Shen
Pages: 8765-8780
Published online: 27 Sep 2019
AbstractforPreoperative Hyponatremia And Hypocalcemia Predict Poor Prognosis In Elderly Gastric Cancer Patients | Full Text | References | PDF (1.7 MB) | EPUB
  • 100 Views
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Article
The CRP/Albumin Ratio Predicts Survival And Monitors Chemotherapeutic Effectiveness In Patients With Advanced Pancreatic Cancer
Zhiyao Fan, Kun Fan, Yitao Gong, Qiuyi Huang, Chao Yang, He Cheng, Kaizhou Jin, Quanxing Ni, Xianjun Yu, Guopei Luo & Chen Liu
Pages: 8781-8788
Published online: 30 Sep 2019
AbstractforThe CRP/Albumin Ratio Predicts Survival And Monitors Chemotherapeutic Effectiveness In Patients With Advanced Pancreatic Cancer | Full Text | References | PDF (1.9 MB) | EPUB
  • 88 Views
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Article
RETRACTED ARTICLE: The Long Noncoding RNA LINC00908 Facilitates Hepatocellular Carcinoma Progression Via Interaction With Sox-4
Xinhua Hu, Qingxiang Li & Jinfeng Zhang
Pages: 8789-8797
Published online: 30 Sep 2019
AbstractforRETRACTED ARTICLE: The Long Noncoding RNA LINC00908 Facilitates Hepatocellular Carcinoma Progression Via Interaction With Sox-4 | PDF (6.2 MB)
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Article
Combination Of ALBI And APRI To Predict Post-Hepatectomy Liver Failure After Liver Resection For HBV-Related HCC Patients
Rong-yun Mai, Yan-yan Wang, Tao Bai, Jie Chen, Bang-de Xiang, Guo-bin Wu, Fei-xiang Wu, Le-qun Li & Jia-zhou Ye
Pages: 8799-8806
Published online: 02 Oct 2019
AbstractforCombination Of ALBI And APRI To Predict Post-Hepatectomy Liver Failure After Liver Resection For HBV-Related HCC Patients | Full Text | References | PDF (1.4 MB) | EPUB
  • 81 Views
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Article
Prognostic Usefulness Of Advanced Lung Cancer Inflammation Index In Locally-Advanced Pancreatic Carcinoma Patients Treated With Radical Chemoradiotherapy
Erkan Topkan, Huseyin Mertsoylu, Yurday Ozdemir, Ahmet Sezer, Ahmet Kucuk, Ali Ayberk Besen, Ozgur Ozyilkan & Ugur Selek
Pages: 8807-8815
Published online: 07 Oct 2019
AbstractforPrognostic Usefulness Of Advanced Lung Cancer Inflammation Index In Locally-Advanced Pancreatic Carcinoma Patients Treated With Radical Chemoradiotherapy | Full Text | References | PDF (2.3 MB) | EPUB
  • 62 Views
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Review

Article
Midostaurin In Acute Myeloid Leukemia: An Evidence-Based Review And Patient Selection
Hussein A Abbas, Mansour Alfayez, Tapan Kadia, Farhad Ravandi-Kashani & Naval Daver
Pages: 8817-8828
Published online: 04 Oct 2019
AbstractforMidostaurin In Acute Myeloid Leukemia: An Evidence-Based Review And Patient Selection | Full Text | References | PDF (1.1 MB) | EPUB
  • 225 Views
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Article
Physician And Patient Barriers To Radiotherapy Service Access: Treatment Referral Implications
Sara Chierchini, Gianluca Ingrosso, Simonetta Saldi, Fabrizio Stracci & Cynthia Aristei
Pages: 8829-8833
Published online: 07 Oct 2019
AbstractforPhysician And Patient Barriers To Radiotherapy Service Access: Treatment Referral Implications | Full Text | References | PDF (283.6 KB) | EPUB
  • 136 Views
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Original Research

Article
The Prediction Of Epidermal Growth Factor Receptor Mutation And Prognosis Of EGFR Tyrosine Kinase Inhibitor By Serum Ferritin In Advanced NSCLC
Zhen Wu, Yu Dai & Liang-An Chen
Pages: 8835-8843
Published online: 07 Oct 2019
AbstractforThe Prediction Of Epidermal Growth Factor Receptor Mutation And Prognosis Of EGFR Tyrosine Kinase Inhibitor By Serum Ferritin In Advanced NSCLC | Full Text | References | PDF (918.7 KB) | EPUB
  • 63 Views
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Article
Effect Of Surgical Safety Checklists On Gastric Cancer Outcomes: A Single-Center Retrospective Study
Deliang Yu & Qingchuan Zhao
Pages: 8845-8853
Published online: 08 Oct 2019
AbstractforEffect Of Surgical Safety Checklists On Gastric Cancer Outcomes: A Single-Center Retrospective Study | Full Text | References | PDF (1 MB) | EPUB
  • 67 Views
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Review

Article
Survival advantage and clinicopathological significance of microRNA-22 in cancers: a meta-analysis
Qingming Xiang, Zhenxian Xiang, Rongzhang Dou & Bin Xiong
Pages: 8855-8868
Published online: 08 Oct 2019
AbstractforSurvival advantage and clinicopathological significance of microRNA-22 in cancers: a meta-analysis | Full Text | References | PDF (9.9 MB) | EPUB
  • 52 Views
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Original Research

Article
A Study Of Efficacy And Safety With Apatinib Or Apatinib Combined With Chemotherapy In Recurrent/advanced Ovarian Cancer Patients
Mi Yang, Xiufeng Liu, Cheng Zhang, Feng Liao, Zixiong Li, Xianwen Luo, Yiran Sun & Chao Chen
Pages: 8869-8876
Published online: 09 Oct 2019
AbstractforA Study Of Efficacy And Safety With Apatinib Or Apatinib Combined With Chemotherapy In Recurrent/advanced Ovarian Cancer Patients | Full Text | References | PDF (465.7 KB) | EPUB
  • 55 Views
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Article
Serum Fibrinogen Is An Independent Prognostic Factor In Operable Esophageal Squamous Carcinoma: A Real-World Study
Yan Zheng, Yin Li, Wenqun Xing, Jianjun Qin, Xianben Liu, Ruixiang Zhang, Haibo Sun & Xiankai Chen
Pages: 8877-8883
Published online: 11 Oct 2019
AbstractforSerum Fibrinogen Is An Independent Prognostic Factor In Operable Esophageal Squamous Carcinoma: A Real-World Study | Full Text | References | PDF (1.1 MB) | EPUB
  • 62 Views
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Article
Time Trends And Age-Period-Cohort Effects On The Incidence Of Gastric Cancer In Changle From 2003 To 2012
Yongtian Lin, Shaowei Lin, Jianshun Chen, Lici Chen, Tao Tao & Siying Wu
Pages: 8885-8892
Published online: 10 Oct 2019
AbstractforTime Trends And Age-Period-Cohort Effects On The Incidence Of Gastric Cancer In Changle From 2003 To 2012 | Full Text | References | PDF (1.4 MB) | EPUB
  • 54 Views
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Article
Ten-Year Outcomes Of Intensity-Modulated Radiotherapy (IMRT) Combine With Chemotherapy Versus IMRT Alone For Stage II Nasopharyngeal Carcinoma In The Real-World Study (RWD)
Xing-Chen Ding, Ping-Ping Fan, Peng Xie, Bing-Jie Fan, Jia Yang, Li-Yang Jiang, Xin-Bin Bai, Jin-Ming Yu & Man Hu
Pages: 8893-8903
Published online: 10 Oct 2019
AbstractforTen-Year Outcomes Of Intensity-Modulated Radiotherapy (IMRT) Combine With Chemotherapy Versus IMRT Alone For Stage II Nasopharyngeal Carcinoma In The Real-World Study (RWD) | Full Text | References | PDF (398 KB) | EPUB
  • 74 Views
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Article
Downregulation Of LncRNA PMS2L2 In Endometrial Adenocarcinoma Upon Carboplatin Treatment
Dan Zhang, Xiuyun Sun & Yuyang Zhang
Pages: 8905-8910
Published online: 10 Oct 2019
AbstractforDownregulation Of LncRNA PMS2L2 In Endometrial Adenocarcinoma Upon Carboplatin Treatment | Full Text | References | PDF (4 MB) | EPUB
  • 54 Views
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Article
Metadherin Promotes Malignant Phenotypes And Induces Beta-Catenin Nuclear Translocation And Epithelial–Mesenchymal Transition In Gastric Cancer
Di Feng, Xiaoyu Yu, Xing Tian, Hongxue Meng, Yang Jiang, HongTao Song, WenQi Li, HaoCheng Zhang & Jingshu Geng
Pages: 8911-8921
Published online: 11 Oct 2019
AbstractforMetadherin Promotes Malignant Phenotypes And Induces Beta-Catenin Nuclear Translocation And Epithelial–Mesenchymal Transition In Gastric Cancer | Full Text | References | PDF (7.1 MB) | EPUB
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Article
RETRACTED ARTICLE: Isovitexin Suppresses Cancer Stemness Property And Induces Apoptosis Of Osteosarcoma Cells By Disruption Of The DNMT1/miR-34a/Bcl-2 Axis
Xiao Liang, Chang Xu, Xiaocheng Cao & Wanchun Wang
Pages: 8923-8936
Published online: 15 Oct 2019
AbstractforRETRACTED ARTICLE: Isovitexin Suppresses Cancer Stemness Property And Induces Apoptosis Of Osteosarcoma Cells By Disruption Of The DNMT1/miR-34a/Bcl-2 Axis | PDF (5.1 MB)
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Article
Novel Hsp90 Inhibitor C086 Potently Inhibits Non-Small Cell Lung Cancer Cells As A Single Agent Or In Combination With Gefitinib
Liman Wang, Yingjuan Fan, Hanhao Mei, Yang Liu, Lianru Zhang, Jianhua Xu & Xuhui Huang
Pages: 8937-8945
Published online: 16 Oct 2019
AbstractforNovel Hsp90 Inhibitor C086 Potently Inhibits Non-Small Cell Lung Cancer Cells As A Single Agent Or In Combination With Gefitinib | Full Text | References | PDF (8.7 MB) | EPUB
  • 63 Views
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Review

Review Article
Genetic And Epigenetic Regulation Of E-Cadherin Signaling In Human Hepatocellular Carcinoma
Xiaoxiao Fan, Shengxi Jin, Yirun Li, Parikshit Asutosh Khadaroo, Yili Dai, Lifeng He, Daizhan Zhou & Hui Lin
Pages: 8947-8963
Published online: 16 Oct 2019
AbstractforGenetic And Epigenetic Regulation Of E-Cadherin Signaling In Human Hepatocellular Carcinoma | Full Text | References | PDF (2.7 MB) | EPUB
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Original Research

Article
Prognostic Significance Of Platelet-To-Lymphocyte Ratio (PLR) And Mean Platelet Volume (MPV) During Etoposide-Based First-Line Treatment In Small Cell Lung Cancer Patients
Xia-Bo Shen, Yong Wang, Ben-Jie Shan, Lin Lin, Li Hao, Yu Liu, Wei Wang & Yue-Yin Pan
Pages: 8965-8975
Published online: 17 Oct 2019
AbstractforPrognostic Significance Of Platelet-To-Lymphocyte Ratio (PLR) And Mean Platelet Volume (MPV) During Etoposide-Based First-Line Treatment In Small Cell Lung Cancer Patients | Full Text | References | PDF (5.6 MB) | EPUB
  • 64 Views
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Article
A Multi-Element Expression Score Is A Prognostic Factor In Glioblastoma Multiforme
Jun-Qi Li, Qian-Ting Wang, Ying Nie, Yun-Peng Xiao, Tao Lin, Ru-Jin Han, Zhe Li, Yu-Ying Fan, Xiao-Hui Yuan, Yue-Ming Wang, Jian Zhang, You-Wen He & Hua-Xin Liao
Pages: 8977-8989
Published online: 17 Oct 2019
AbstractforA Multi-Element Expression Score Is A Prognostic Factor In Glioblastoma Multiforme | Full Text | References | PDF (5.5 MB) | EPUB
  • 68 Views
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Article
TCDD-Inducible Poly-ADP-Ribose Polymerase (TIPARP), A Novel Therapeutic Target Of Breast Cancer
Lin Cheng, Zhi Li, Yu-Zhou Huang, Xu Zhang, Xin-Yuan Dai, Liang Shi, Pei-Wen Xi, Ji-Fu Wei & Qiang Ding
Pages: 8991-9004
Published online: 18 Oct 2019
AbstractforTCDD-Inducible Poly-ADP-Ribose Polymerase (TIPARP), A Novel Therapeutic Target Of Breast Cancer | Full Text | References | PDF (11.1 MB) | EPUB
  • 118 Views
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Article
Berberine induces apoptosis in non-small-cell lung cancer cells by upregulating miR-19a targeting tissue factor
Qian-qian Chen, Jia-min Shi, Zhou Ding, Qing Xia, Tian-sheng Zheng, Yan-bei Ren, Ming Li & Li-hong Fan
Pages: 9005-9015
Published online: 21 Oct 2019
AbstractforBerberine induces apoptosis in non-small-cell lung cancer cells by upregulating miR-19a targeting tissue factor | Full Text | References | PDF (5 MB) | EPUB
  • 130 Views
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Article
Clinical And Imageological Features Of Lung Squamous Cell Carcinoma With EGFR Mutations
Xuejuan Gao, Junjie Zhu, Linsong Chen, Yan Jiang, Xiao Zhou, Jianwei Shuai & Yanfeng Zhao
Pages: 9017-9024
Published online: 21 Oct 2019
AbstractforClinical And Imageological Features Of Lung Squamous Cell Carcinoma With EGFR Mutations | Full Text | References | PDF (1.2 MB) | EPUB
  • 44 Views
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Article
Prognostic Value Of Preoperative Systemic Inflammatory Biomarkers In Patients With Gallbladder Cancer And The Establishment Of A Nomogram
Yan Deng, Feng Zhang, Xiao Yu, Cheng-Long Huo, Zhen-Gang Sun & Shuai Wang
Pages: 9025-9035
Published online: 21 Oct 2019
AbstractforPrognostic Value Of Preoperative Systemic Inflammatory Biomarkers In Patients With Gallbladder Cancer And The Establishment Of A Nomogram | Full Text | References | PDF (2.7 MB) | EPUB
  • 68 Views
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Article
Nomogram For Preoperative Prediction Of Microvascular Invasion Risk In Hepatocellular Carcinoma
Guangtong Deng, Lei Yao, Furong Zeng, Liang Xiao & Zhiming Wang
Pages: 9037-9045
Published online: 22 Oct 2019
AbstractforNomogram For Preoperative Prediction Of Microvascular Invasion Risk In Hepatocellular Carcinoma | Full Text | References | PDF (4 MB) | EPUB
  • 68 Views
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Corrigendum

Correction
Long Noncoding RNA GAS5 Acts As A Tumor Suppressor In Laryngeal Squamous Cell Carcinoma Via miR-21 [Corrigendum]
Page: 9047
Published online: 23 Oct 2019
CitationforLong Noncoding RNA GAS5 Acts As A Tumor Suppressor In Laryngeal Squamous Cell Carcinoma Via miR-21 [Corrigendum] | Full Text | PDF (147.7 KB) | EPUB
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Original Research

Article
Comparison Of Long Term Results Between Matched Chemoradiotherapy And Surgery For Limited Stage Small Cell Lung Cancer
Meng-yuan Chen, Xiao Hu, Yong Bao, Jin Wang, Ya-mei Chen, Yu-jin Xu, Jianan Jin & Ming Chen
Pages: 9049-9055
Published online: 23 Oct 2019
AbstractforComparison Of Long Term Results Between Matched Chemoradiotherapy And Surgery For Limited Stage Small Cell Lung Cancer | Full Text | References | PDF (1.7 MB) | EPUB
  • 83 Views
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Article
Fusobacterium nucleatum prevents apoptosis in colorectal cancer cells via the ANO1 pathway
Pei Lu, Minyi Xu, Zhongbo Xiong, Fangfang Zhou & Lei Wang
Pages: 9057-9066
Published online: 29 Oct 2019
AbstractforFusobacterium nucleatum prevents apoptosis in colorectal cancer cells via the ANO1 pathway | Full Text | References | PDF (963.8 KB) | EPUB
  • 113 Views
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Article
Platelet Volume Is Reduced In Metastasing Breast Cancer: Blood Profiles Reveal Significant Shifts
Ming-ming Li, Chen-xi Yue, Shuang Fu, Xin Zhang, Chang-Jiu Zhao & Rui-tao Wang
Pages: 9067-9072
Published online: 24 Oct 2019
AbstractforPlatelet Volume Is Reduced In Metastasing Breast Cancer: Blood Profiles Reveal Significant Shifts | Full Text | References | PDF (564.5 KB) | EPUB
  • 70 Views
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Article
Expression Of Cyclin D1 Protein Isoforms And Its Prognostic Significance In Cervical Cancer
Jiahui Gu, Xinyu Zhang, Zhuo Yang & Ning Wang
Pages: 9073-9083
Published online: 24 Oct 2019
AbstractforExpression Of Cyclin D1 Protein Isoforms And Its Prognostic Significance In Cervical Cancer | Full Text | References | PDF (5.2 MB) | EPUB
  • 79 Views
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Article
Baseline FDG Uptake And Peripheral Lymphocyte-Monocyte Ratio For Predicting Chemoradiotherapy Response In Patients With Esophageal Squamous Cell Carcinoma
Chunsheng Wang, Kewei Zhao, Yong Huang, Li Ma, Yipeng Song & Minghuan Li
Pages: 9085-9093
Published online: 24 Oct 2019
AbstractforBaseline FDG Uptake And Peripheral Lymphocyte-Monocyte Ratio For Predicting Chemoradiotherapy Response In Patients With Esophageal Squamous Cell Carcinoma | Full Text | References | PDF (676.7 KB) | EPUB
  • 50 Views
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Article
Increased Expression Of SOX2 Predicts A Poor Prognosis And Promotes Malignant Phenotypes In Upper Tract Urothelial Carcinoma
Zhengqing Bao, Yonghao Zhan, Shiming He, Yifan Li, Bao Guan, Qun He, Xinyu Yang, Xuesong Li, Dong Fang & Liqun Zhou
Pages: 9095-9106
Published online: 24 Oct 2019
AbstractforIncreased Expression Of SOX2 Predicts A Poor Prognosis And Promotes Malignant Phenotypes In Upper Tract Urothelial Carcinoma | Full Text | References | PDF (7.2 MB) | EPUB
  • 86 Views
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Article
Comparative performance of inflammation-based prognostic scores in patients operated for intrahepatic cholangiocarcinoma
Jiajia Lin, Tingting Fang, Mengxuan Zhu, Xin Xu, Juan Zhang, Susu Zheng, Chuyu Jing, Meixia Zhang, Binbin Liu & Boheng Zhang
Pages: 9107-9119
Published online: 30 Oct 2019
AbstractforComparative performance of inflammation-based prognostic scores in patients operated for intrahepatic cholangiocarcinoma | Full Text | References | PDF (2.3 MB) | EPUB
  • 67 Views
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Article
Imaging-Based Individualized Response Prediction Of Carbon Ion Radiotherapy For Prostate Cancer Patients
Shuang Wu, Yining Jiao, Yafang Zhang, Xuhua Ren, Ping Li, Qi Yu, Qing Zhang, Qian Wang & Shen Fu
Pages: 9121-9131
Published online: 24 Oct 2019
AbstractforImaging-Based Individualized Response Prediction Of Carbon Ion Radiotherapy For Prostate Cancer Patients | Full Text | References | PDF (6.6 MB) | EPUB
  • 103 Views
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Article
Silencing Of hsa_circ_0008450 Represses Hepatocellular Carcinoma Progression Through Regulation Of microRNA-214-3p/EZH2 Axis
Tianyu Lin, Yi Dai, Xinli Guo, Wenchao Chen, Jiangang Zhao, Liping Cao & Zhengrong Wu
Pages: 9133-9143
Published online: 24 Oct 2019
AbstractforSilencing Of hsa_circ_0008450 Represses Hepatocellular Carcinoma Progression Through Regulation Of microRNA-214-3p/EZH2 Axis | Full Text | References | PDF (6.5 MB) | EPUB
  • 71 Views
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Methodology

OSacc: Gene Expression-Based Survival Analysis Web Tool For Adrenocortical Carcinoma
Longxiang Xie, Qiang Wang, Fangmei Nan, Linna Ge, Yifang Dang, Xiaoxiao Sun, Ning Li, Huan Dong, Yali Han, Guosen Zhang, Wan Zhu & Xiangqian Guo
Pages: 9145-9152
Published online: 24 Oct 2019
AbstractforOSacc: Gene Expression-Based Survival Analysis Web Tool For Adrenocortical Carcinoma | Full Text | References | PDF (4.3 MB) | EPUB
  • 123 Views
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Original Research

Article
Ras-ERK1/2 Signaling Promotes The Development Of Osteosarcoma By Regulating H2BK12ac Through CBP
Xianlun Xu, Hao Yu & Yupeng Xu
Pages: 9153-9163
Published online: 24 Oct 2019
AbstractforRas-ERK1/2 Signaling Promotes The Development Of Osteosarcoma By Regulating H2BK12ac Through CBP | Full Text | References | PDF (5.6 MB) | EPUB
  • 63 Views
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Article
Transcriptional Characterization Of The Tumor Immune Microenvironment And Its Prognostic Value For Locally Advanced Lung Adenocarcinoma In A Chinese Population
Yuqiao Chen, Huan Chen, Beibei Mao, Yuan Zhou, Xinying Shi, Lu Tang, Hong Jiang, Guo Wang & Wei Zhuang
Pages: 9165-9173
Published online: 31 Oct 2019
AbstractforTranscriptional Characterization Of The Tumor Immune Microenvironment And Its Prognostic Value For Locally Advanced Lung Adenocarcinoma In A Chinese Population | Full Text | References | PDF (5.8 MB) | EPUB
  • 66 Views
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Article
USP13 serves as a tumor suppressor via the PTEN/AKT pathway in oral squamous cell carcinoma
Zhi Qu, Ran Zhang, Meng Su & Weixian Liu
Pages: 9175-9183
Published online: 31 Oct 2019
AbstractforUSP13 serves as a tumor suppressor via the PTEN/AKT pathway in oral squamous cell carcinoma | Full Text | References | PDF (1.9 MB) | EPUB
  • 112 Views
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Article
The Diagnostic Value Of Using 18F-Fluorodeoxyglucose Positron Emission Tomography To Differentiate Between Low- And High-Grade Meningioma
Lingyang Hua, Fengchun Hua, Hongda Zhu, Jiaojiao Deng, Daijun Wang, Shihai Luan, Hailiang Tang, Yihui Guan, Qing Xie & Ye Gong
Pages: 9185-9193
Published online: 25 Oct 2019
AbstractforThe Diagnostic Value Of Using 18F-Fluorodeoxyglucose Positron Emission Tomography To Differentiate Between Low- And High-Grade Meningioma | Full Text | References | PDF (2.4 MB) | EPUB
  • 59 Views
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Article
Cost-Effectiveness Analysis Of Ceritinib And Alectinib Versus Crizotinib In The Treatment Of Anaplastic Lymphoma Kinase-Positive Advanced Non-Small Cell Lung Cancer
Maobai Liu, Longfeng Zhang, Qishu Huang, Na Li, Bin Zheng & Hongfu Cai
Pages: 9195-9202
Published online: 25 Oct 2019
AbstractforCost-Effectiveness Analysis Of Ceritinib And Alectinib Versus Crizotinib In The Treatment Of Anaplastic Lymphoma Kinase-Positive Advanced Non-Small Cell Lung Cancer | Full Text | References | PDF (2.4 MB) | EPUB
  • 127 Views
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Article
Micheliolide Inhibits Liver Cancer Cell Growth Via Inducing Apoptosis And Perturbing Actin Cytoskeleton
Lili Yu, Wancheng Chen, Qingshuang Tang & Kai-Yuan Ji
Pages: 9203-9212
Published online: 29 Oct 2019
AbstractforMicheliolide Inhibits Liver Cancer Cell Growth Via Inducing Apoptosis And Perturbing Actin Cytoskeleton | Full Text | References | PDF (6.6 MB) | EPUB
  • 70 Views
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Article
Development and validation of a novel diagnostic model for assessing lung cancer metastasis in a Chinese population based on multicenter real-world data
Yiyong Yao, Cunling Yan, Wei Zhang, San-Gang Wu, Jie Guan, Gang Zeng, Qiang Du, Chun Huang, Hui Zhang, Huiling Wang, Yanfeng Hou, Zhiyan Li, Lixin Wang, Yijie Zheng & Xun Li
Pages: 9213-9223
Published online: 29 Oct 2019
AbstractforDevelopment and validation of a novel diagnostic model for assessing lung cancer metastasis in a Chinese population based on multicenter real-world data | Full Text | References | PDF (2.8 MB) | EPUB
  • 55 Views
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Article
Upregulation Of circMMP9 Promotes Osteosarcoma Progression Via Targeting miR-1265/CHI3L1 Axis
Guangjie Pan, Ting Hu, Xuewu Chen & Chao Zhang
Pages: 9225-9231
Published online: 29 Oct 2019
AbstractforUpregulation Of circMMP9 Promotes Osteosarcoma Progression Via Targeting miR-1265/CHI3L1 Axis | Full Text | References | PDF (4 MB) | EPUB
  • 58 Views
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Article
Population-Based Incidence, Mortality, And Survival For Gastrointestinal Cancers During 2006–2016 In Wuhan, Central China
Yao Cheng, Jianhua Liu, Qing Liao, Xuejiao Hu, Hongyan Lv, Peiyan Ding, Shaofa Nie & Li Tan
Pages: 9233-9241
Published online: 29 Oct 2019
AbstractforPopulation-Based Incidence, Mortality, And Survival For Gastrointestinal Cancers During 2006–2016 In Wuhan, Central China | Full Text | References | PDF (3.1 MB) | EPUB
  • 57 Views
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Article
Real-World Data Of Osimertinib In Patients With Pretreated Non-Small Cell Lung Cancer: A Retrospective Study
Yuxin Mu, Puyuan Xing, Xuezhi Hao, Yan Wang & Junling Li
Pages: 9243-9251
Published online: 30 Oct 2019
AbstractforReal-World Data Of Osimertinib In Patients With Pretreated Non-Small Cell Lung Cancer: A Retrospective Study | Full Text | References | PDF (1.2 MB) | EPUB
  • 120 Views
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Article
Pancreatic Ductal Adenocarcinoma: Machine Learning–Based Quantitative Computed Tomography Texture Analysis For Prediction Of Histopathological Grade
Wenli Qiu, Na Duan, Xiao Chen, Shuai Ren, Yifen Zhang, Zhongqiu Wang & Rong Chen
Pages: 9253-9264
Published online: 30 Oct 2019
AbstractforPancreatic Ductal Adenocarcinoma: Machine Learning–Based Quantitative Computed Tomography Texture Analysis For Prediction Of Histopathological Grade | Full Text | References | PDF (8.7 MB) | EPUB
  • 121 Views
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Article
Serum Apolipoprotein A-I Combined With C-Reactive Protein Serves As A Novel Prognostic Stratification System For Colorectal Cancer
Juan Ye, Qiu-yun Luo, Xue-ping Wang, Zhen-yi Liu, Mei-xian Chen, Hao Huang & Lin Zhang
Pages: 9265-9276
Published online: 30 Oct 2019
AbstractforSerum Apolipoprotein A-I Combined With C-Reactive Protein Serves As A Novel Prognostic Stratification System For Colorectal Cancer | Full Text | References | PDF (3.4 MB) | EPUB
  • 57 Views
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Review

Review Article
The role of digital breast tomosynthesis in breast cancer screening: a manufacturer- and metrics-specific analysis
A Hadjipanteli, M Kontos & A Constantinidou
Pages: 9277-9296
Published online: 31 Oct 2019
AbstractforThe role of digital breast tomosynthesis in breast cancer screening: a manufacturer- and metrics-specific analysis | Full Text | References | PDF (1.3 MB) | EPUB
  • 129 Views
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Original Research

Article
Clinical Characteristics And Outcome Of Biphenotypic Acute Leukemia: 10 Case Reports And Literature Review
Jifeng Yu, Yingmei Li, Haizhou Xing, Yue Pan, Hui Sun, Dingming Wan, Yanfang Liu, Xinsheng Xie, Chong Wang, Ling Sun, Kai Sun & Zhongxing Jiang
Pages: 9297-9306
Published online: 31 Oct 2019
AbstractforClinical Characteristics And Outcome Of Biphenotypic Acute Leukemia: 10 Case Reports And Literature Review | Full Text | References | PDF (875.5 KB) | EPUB
  • 82 Views
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Article
Population-Based Analysis Of The Use Of Radium-223 For Bone-Metastatic Castration-Resistant Prostate Cancer In Ontario, And Of Factors Associated With Treatment Completion And Outcome
Sierra Cheng, Vanessa Arciero, Hanan Goldberg, Camilla Tajzler, Aileen Manganaro, Natascha Kozlowski, Leigha Rowbottom, Rachel McDonald, Ronald Chow, Gaurav Vasisht, Sharon Shaji, Emily Chu Lee Wong, Michele Petrovic, Liying Zhang, Cameron Phillips, Pawel Zalewski, Anil Kapoor, Neil E Fleshner, Edward Chow & Urban Emmenegger
Pages: 9307-9319
Published online: 31 Oct 2019
AbstractforPopulation-Based Analysis Of The Use Of Radium-223 For Bone-Metastatic Castration-Resistant Prostate Cancer In Ontario, And Of Factors Associated With Treatment Completion And Outcome | Full Text | References | PDF (3.2 MB) | EPUB
  • 58 Views
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Article
Efficacy Of Apatinib In Transcatheter Arterial Chemoembolization (TACE) Refractory Intermediate And Advanced-Stage Hepatocellular carcinoma：A Propensity Score Matching Analysis
Zhiyu Qiu, Lujun Shen, Shuanggang Chen, Han Qi, Fei Cao, Lin Xie & Weijun Fan
Pages: 9321-9330
Published online: 01 Nov 2019
AbstractforEfficacy Of Apatinib In Transcatheter Arterial Chemoembolization (TACE) Refractory Intermediate And Advanced-Stage Hepatocellular carcinoma：A Propensity Score Matching Analysis | Full Text | References | PDF (2.6 MB) | EPUB
  • 69 Views
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Article
Distribution Of Brain Metastasis From Lung Cancer
Guangyu Wang, Jiying Xu, Yana Qi, Jianjun Xiu, Ranran Li & Mingyong Han
Pages: 9331-9338
Published online: 01 Nov 2019
AbstractforDistribution Of Brain Metastasis From Lung Cancer | Full Text | References | PDF (343.3 KB) | EPUB
  • 282 Views
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Article
The Cytoplasmic Expression Of CLDN12 Predicts An Unfavorable Prognosis And Promotes Proliferation And Migration Of Osteosarcoma
Xiaoqing Tian, YinFeng He, Zhe Han, HongMin Su & Chao Chu
Pages: 9339-9351
Published online: 01 Nov 2019
AbstractforThe Cytoplasmic Expression Of CLDN12 Predicts An Unfavorable Prognosis And Promotes Proliferation And Migration Of Osteosarcoma | Full Text | References | PDF (6.1 MB) | EPUB
  • 63 Views
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Article
MST4 Predicts Poor Prognosis And Promotes Metastasis By Facilitating Epithelial–Mesenchymal Transition In Gastric Cancer
Taiyuan Li, Li Deng, Xin He, Gongan Jiang, Fang Hu, Shanping Ye, Yu You, Jinzhong Duanmu, Hua Dai, Guodong Huang, Cheng Tang & Xiong Lei
Pages: 9353-9369
Published online: 05 Nov 2019
AbstractforMST4 Predicts Poor Prognosis And Promotes Metastasis By Facilitating Epithelial–Mesenchymal Transition In Gastric Cancer | Full Text | References | PDF (11.6 MB) | EPUB
  • 69 Views
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Article
RETRACTED ARTICLE: LncRNA ASB16-AS1 Promotes Growth And Invasion Of Hepatocellular Carcinoma Through Regulating miR-1827/FZD4 Axis And Activating Wnt/β-Catenin Pathway
Xiaoxiao Yao, Guangqiang You, Chen Zhou & Dan Zhang
Pages: 9371-9378
Published online: 07 Nov 2019
AbstractforRETRACTED ARTICLE: LncRNA ASB16-AS1 Promotes Growth And Invasion Of Hepatocellular Carcinoma Through Regulating miR-1827/FZD4 Axis And Activating Wnt/β-Catenin Pathway | PDF (6 MB)
  • 15 Views
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Article
Development And Validation Of A Simple Model For Detection Of Early Hepatocellular Carcinoma In A Liver Cirrhosis Cohort
Tao Li, Hongguang Li, Aihua Wang, Xiaoyan Su, Jingfang Zhao, Yi Cui, Jun Liu & Jinhua Hu
Pages: 9379-9386
Published online: 05 Nov 2019
AbstractforDevelopment And Validation Of A Simple Model For Detection Of Early Hepatocellular Carcinoma In A Liver Cirrhosis Cohort | Full Text | References | PDF (2.4 MB) | EPUB
  • 59 Views
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Article
Local Tumor Ischemia-Reperfusion Mediated By Ultrasound-Targeted Microbubble Destruction Enhances The Anti-Tumor Efficacy Of Doxorubicin Chemotherapy
Manxiang Wu, Zhuqing Song, Shiyu Zhang, Qing Dan, Caiyun Tang, Chao Peng, Yu Liang, Li Zhang, Hao Wang & Yingjia Li
Pages: 9387-9395
Published online: 05 Nov 2019
AbstractforLocal Tumor Ischemia-Reperfusion Mediated By Ultrasound-Targeted Microbubble Destruction Enhances The Anti-Tumor Efficacy Of Doxorubicin Chemotherapy | Full Text | References | PDF (3.6 MB) | EPUB
  • 60 Views
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Review

Review Article
Single-Fraction Radiotherapy (SFRT) For Bone Metastases: Patient Selection And Perspectives
Mauro Loi, Joost J Nuyttens, Isacco Desideri, Daniela Greto & Lorenzo Livi
Pages: 9397-9408
Published online: 05 Nov 2019
AbstractforSingle-Fraction Radiotherapy (SFRT) For Bone Metastases: Patient Selection And Perspectives | Full Text | References | PDF (608.8 KB) | EPUB
  • 92 Views
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Original Research

Article
Prognostic Significance Of The Inflammatory Index-Based Scoring System In Patients Preliminarily Diagnosed With Multiple Myeloma In The Bortezomib-Based Chemotherapy Era
Siwei Liu, Jie Shi, Honggang Guo, Fangfang Xu, Min Wei, Kai Sun & Yuqing Chen
Pages: 9409-9420
Published online: 05 Nov 2019
AbstractforPrognostic Significance Of The Inflammatory Index-Based Scoring System In Patients Preliminarily Diagnosed With Multiple Myeloma In The Bortezomib-Based Chemotherapy Era | Full Text | References | PDF (3.6 MB) | EPUB
  • 97 Views
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Article
Glycodelin As A Biomarker Of Advanced Lung Adenocarcinoma Brain Metastases In Patients Treated With EGFR Tyrosine Kinase Inhibitors
Zexu Ni, Lingling Zhang, Jinhua Zheng, Xiaojie Su & Shucai Zhang
Pages: 9421-9425
Published online: 06 Nov 2019
AbstractforGlycodelin As A Biomarker Of Advanced Lung Adenocarcinoma Brain Metastases In Patients Treated With EGFR Tyrosine Kinase Inhibitors | Full Text | References | PDF (903.4 KB) | EPUB
  • 50 Views
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Article
The Prognostic Value Of Lymph Node Ratio In Patients With N2 Stage Lung Squamous Cell Carcinoma: A Nomogram And Heat Map Approach
Guoshu Bi, Tao Lu, Guangyu Yao, Yunyi Bian, Mengnan Zhao, Yiwei Huang, Yi Zhang, Liang Xue, Cheng Zhan & Hong Fan
Pages: 9427-9437
Published online: 06 Nov 2019
AbstractforThe Prognostic Value Of Lymph Node Ratio In Patients With N2 Stage Lung Squamous Cell Carcinoma: A Nomogram And Heat Map Approach | Full Text | References | PDF (6.9 MB) | EPUB
  • 53 Views
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Article
Nomogram For The Prediction Of Malignancy In Small (8–20 mm) Indeterminate Solid Solitary Pulmonary Nodules In Chinese Populations
Xiao-Bo Chen, Rui-Ying Yan, Ke Zhao, Da-Fu Zhang, Ya-Jun Li, Lin Wu, Xing-Xiang Dong, Ying Chen, De-Pei Gao, Ying-Ying Ding, Xi-Cai Wang & Zhen-Hui Li
Pages: 9439-9448
Published online: 06 Nov 2019
AbstractforNomogram For The Prediction Of Malignancy In Small (8–20 mm) Indeterminate Solid Solitary Pulmonary Nodules In Chinese Populations | Full Text | References | PDF (1.2 MB) | EPUB
  • 72 Views
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Article
Risk Stratification Of Diffuse Large B-Cell Lymphoma With Interim PET/CT By Combining Deauville Scores And International Prognostic Index
Hongwei Sun, Zhan Yu, Ning Ma, Jie Zhou, Rongrong Tian, Ming Zhao & Tong Wang
Pages: 9449-9457
Published online: 06 Nov 2019
AbstractforRisk Stratification Of Diffuse Large B-Cell Lymphoma With Interim PET/CT By Combining Deauville Scores And International Prognostic Index | Full Text | References | PDF (1.1 MB) | EPUB
  • 57 Views
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Article
Nomogram-Integrated C-Reactive Protein/Albumin Ratio Predicts Efficacy And Prognosis In Patients With Thoracic Esophageal Squamous Cell Carcinoma Receiving Chemoradiotherapy
Han Zhang, Xin-Wei Guo, Xiao-Xiang Yin, Yang-Chen Liu & Sheng-Jun Ji
Pages: 9459-9468
Published online: 06 Nov 2019
AbstractforNomogram-Integrated C-Reactive Protein/Albumin Ratio Predicts Efficacy And Prognosis In Patients With Thoracic Esophageal Squamous Cell Carcinoma Receiving Chemoradiotherapy | Full Text | References | PDF (4.7 MB) | EPUB
  • 67 Views
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Article
A Molecular Epidemiological Analysis Of Programmed Cell Death Ligand-1 (PD-L1) Protein Expression, Mutations And Survival In Non-Small Cell Lung Cancer
Matthew B Schabath, Tapashi B Dalvi, Hongyue A Dai, Alan L Crim, Anita Midha, Norah Shire, Nicholas T Gimbrone, Jill Walker, Danielle M Greenawalt, David Lawrence, James R Rigas, Robert Brody, Danielle Potter, Naveen S Kumar, Shane A Huntsman & Jhanelle E Gray
Pages: 9469-9481
Published online: 07 Nov 2019
AbstractforA Molecular Epidemiological Analysis Of Programmed Cell Death Ligand-1 (PD-L1) Protein Expression, Mutations And Survival In Non-Small Cell Lung Cancer | Full Text | References | PDF (539.7 KB) | EPUB
  • 66 Views
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Article
Cost-Effectiveness Analysis Of Pembrolizumab In The Treatment Of Advanced Recurrent Metastatic Head And Neck Squamous Cell Carcinoma In China And The United States
Maobai Liu, Sijie Han, Bin Zheng, Hongfu Cai, Jing Yang, Qian Zhuang & Na Li
Pages: 9483-9493
Published online: 11 Nov 2019
AbstractforCost-Effectiveness Analysis Of Pembrolizumab In The Treatment Of Advanced Recurrent Metastatic Head And Neck Squamous Cell Carcinoma In China And The United States | Full Text | References | PDF (3.9 MB) | EPUB
  • 81 Views
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Article
Impact Of ELN Risk Stratification, Induction Chemotherapy Regimens And Hematopoietic Stem Cell Transplantation On Outcomes In Hyperleukocytic Acute Myeloid Leukemia With Initial White Blood Cell Count More Than 100 × 109/L
Shanglong Feng, Li Zhou, Xinhui Zhang, Baolin Tang, Xiaoyu Zhu, Huilan Liu, Zimin Sun & Changcheng Zheng
Pages: 9495-9503
Published online: 08 Nov 2019
AbstractforImpact Of ELN Risk Stratification, Induction Chemotherapy Regimens And Hematopoietic Stem Cell Transplantation On Outcomes In Hyperleukocytic Acute Myeloid Leukemia With Initial White Blood Cell Count More Than 100 × 109/L | Full Text | References | PDF (526.3 KB) | EPUB
  • 97 Views
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Article
Sevoflurane Inhibited Osteosarcoma Cell Proliferation And Invasion Via Targeting miR-203/WNT2B/Wnt/β-Catenin Axis
Meixian Chen, Lisheng Zhou, Zhaoxia Liao, Xijiu Ye, Xujun Xuan, Beibei Gu & Fuding Lu
Pages: 9505-9515
Published online: 11 Nov 2019
AbstractforSevoflurane Inhibited Osteosarcoma Cell Proliferation And Invasion Via Targeting miR-203/WNT2B/Wnt/β-Catenin Axis | Full Text | References | PDF (4.2 MB) | EPUB
  • 59 Views
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Article
5-Aza-CdR Regulates RASSF1A By Inhibiting DNMT1 To Affect Colon Cancer Cell Proliferation, Migration And Apoptosis
Jinyuan Chen, Lixiang Wu, Hong Xu & Shubang Cheng
Pages: 9517-9528
Published online: 08 Nov 2019
Abstractfor5-Aza-CdR Regulates RASSF1A By Inhibiting DNMT1 To Affect Colon Cancer Cell Proliferation, Migration And Apoptosis | Full Text | References | PDF (12.9 MB) | EPUB
  • 86 Views
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Article
miR-1305 Inhibits The Progression Of Non-Small Cell Lung Cancer By Regulating MDM2
Yuxing Cai, Yi Hao, HaiFeng Ren, ZhiGuo Dang, Hui Xu, Xiangfei Xue & Yan Gao
Pages: 9529-9540
Published online: 11 Nov 2019
AbstractformiR-1305 Inhibits The Progression Of Non-Small Cell Lung Cancer By Regulating MDM2 | Full Text | References | PDF (9.6 MB) | EPUB
  • 62 Views
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Article
High-Risk Human Papillomavirus E7 Maintains Stemness Via APH1B In Cervical Cancer Stem-Cell Like Cells
Shizhou Yang, Tingting Chen, Lu Huang, Shanshan Xu, Zhu Cao, Songfa Zhang, Junfen Xu, Yang Li, Yongfang Yue, Weiguo Lu, Xiaodong Cheng & Xing Xie
Pages: 9541-9552
Published online: 12 Nov 2019
AbstractforHigh-Risk Human Papillomavirus E7 Maintains Stemness Via APH1B In Cervical Cancer Stem-Cell Like Cells | Full Text | References | PDF (9.3 MB) | EPUB
  • 67 Views
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Article
Aberrant Expression Of PDCD4/eIF4A1 Signal Predicts Postoperative Recurrence For Early-Stage Oral Squamous Cell Carcinoma
Mengxiang Zhao, Liang Ding, Yan Yang, Sheng Chen, Nisha Zhu, Yong Fu, Yanhong Ni & Zhiyong Wang
Pages: 9553-9562
Published online: 11 Nov 2019
AbstractforAberrant Expression Of PDCD4/eIF4A1 Signal Predicts Postoperative Recurrence For Early-Stage Oral Squamous Cell Carcinoma | Full Text | References | PDF (8 MB) | EPUB
  • 71 Views
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Article
Predictive Role Of Body Composition Parameters In Operable Breast Cancer Patients Treated With Neoadjuvant Chemotherapy
Claudia Omarini, Patrizia Palumbo, Annarita Pecchi, Stefano Draisci, Sara Balduzzi, Cecilia Nasso, Monica Barbolini, Chrystel Isca, Alessandro Bocconi, Luca Moscetti, Silvia Galetti, Giovanni Tazzioli, Pietro Torricelli, Stefano Cascinu & Federico Piacentini
Pages: 9563-9569
Published online: 12 Nov 2019
AbstractforPredictive Role Of Body Composition Parameters In Operable Breast Cancer Patients Treated With Neoadjuvant Chemotherapy | Full Text | References | PDF (1.1 MB) | EPUB
  • 83 Views
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Article
Digital Immune-Related Gene Expression Signatures In High-Grade Serous Ovarian Carcinoma: Developing Prediction Models For Platinum Response
Fabian Mairinger, Agnes Bankfalvi, Kurt Werner Schmid, Elena Mairinger, Pawel Mach, Robert FH Walter, Sabrina Borchert, Sabine Kasimir-Bauer, Rainer Kimmig & Paul Buderath
Pages: 9571-9583
Published online: 12 Nov 2019
AbstractforDigital Immune-Related Gene Expression Signatures In High-Grade Serous Ovarian Carcinoma: Developing Prediction Models For Platinum Response | Full Text | References | PDF (7.2 MB) | EPUB
  • 94 Views
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Article
Knockdown Of CCDC132 Attenuates Gastric Cancer Cells Proliferation And Tumorigenesis By Facilitating DNA Damage Signaling
Xiaowu Xu, Weilang Cao, Wei Sun, Zhaohong Wang, Hui Chen, Zhiqiang Zheng & Xiaomin Yang
Pages: 9585-9597
Published online: 12 Nov 2019
AbstractforKnockdown Of CCDC132 Attenuates Gastric Cancer Cells Proliferation And Tumorigenesis By Facilitating DNA Damage Signaling | Full Text | References | PDF (2.5 MB) | EPUB
  • 67 Views
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Article
Clinical Outcomes And Cost-Effectiveness Of Different Staplers For Lung Lobectomy With Video-Assisted Thoracic Surgery
Xiaoxiong Xiao, Ruimin Chang & Yang Gao
Pages: 9599-9607
Published online: 13 Nov 2019
AbstractforClinical Outcomes And Cost-Effectiveness Of Different Staplers For Lung Lobectomy With Video-Assisted Thoracic Surgery | Full Text | References | PDF (2.2 MB) | EPUB
  • 85 Views
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Article
Integrin α5/ITGA5 Promotes The Proliferation, Migration, Invasion And Progression Of Oral Squamous Carcinoma By Epithelial–Mesenchymal Transition
Yun Deng, Quan Wan & Wangxiang Yan
Pages: 9609-9620
Published online: 13 Nov 2019
AbstractforIntegrin α5/ITGA5 Promotes The Proliferation, Migration, Invasion And Progression Of Oral Squamous Carcinoma By Epithelial–Mesenchymal Transition | Full Text | References | PDF (14.6 MB) | EPUB
  • 129 Views
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Article
Poor Prognosis With Coexistence Of EGFR T790M Mutation And Common EGFR-Activating Mutation In Non- Small Cell Lung Cancer
Xuejuan Gao, Yanfeng Zhao, Yi Bao, Wei Yin, Liyu Liu, Ruchuan Liu, Zhengquan Yu, Xiao Zhou & Jianwei Shuai
Pages: 9621-9630
Published online: 13 Nov 2019
AbstractforPoor Prognosis With Coexistence Of EGFR T790M Mutation And Common EGFR-Activating Mutation In Non- Small Cell Lung Cancer | Full Text | References | PDF (2 MB) | EPUB
  • 59 Views
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Article
Potential Diagnostic Value Of Combining Inflammatory Cell Ratios With Carcinoembryonic Antigen For Colorectal Cancer
Xinxin Li, Dongming Guo, Lingyu Chu, Yiteng Huang, Feiran Zhang, Wei Li & Juntian Chen
Pages: 9631-9640
Published online: 14 Nov 2019
AbstractforPotential Diagnostic Value Of Combining Inflammatory Cell Ratios With Carcinoembryonic Antigen For Colorectal Cancer | Full Text | References | PDF (5.3 MB) | EPUB
  • 73 Views
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Article
PES1 In Liver Cancer: A Prognostic Biomarker With Tumorigenic Roles
Zhuo Fu, Yan Jiao, Yan-Qing Li, Jian-Ji Ke, Yan-Hui Xu, Bao-Xing Jia & Bin Liu
Pages: 9641-9653
Published online: 14 Nov 2019
AbstractforPES1 In Liver Cancer: A Prognostic Biomarker With Tumorigenic Roles | Full Text | References | PDF (3.4 MB) | EPUB
  • 60 Views
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Article
Sentinel Lymph Node Biopsy Was Associated With Favorable Survival Outcomes For Patients With Clinically Node-Negative Asian Melanoma
John Wen-Cheng Chang, Yen-Lin Huang, Yao-Yu Chang, Yung-Feng Lo, Tsung-Ying Ho, Yi-Ting Huang, Huan-Wu Chen & Chiao-En Wu
Pages: 9655-9664
Published online: 14 Nov 2019
AbstractforSentinel Lymph Node Biopsy Was Associated With Favorable Survival Outcomes For Patients With Clinically Node-Negative Asian Melanoma | Full Text | References | PDF (4 MB) | EPUB
  • 57 Views
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Article
Cancer Incidence Trends From 1999 to 2015 And Contributions Of Various Cancer Types To The Overall Burden: Projections To 2030 And Extrapolation Of Economic Burden In Saudi Arabia
Abdul Rahman Jazieh, Omar B Da’ar, Mohammad Alkaiyat, Yasmine A Zaatreh, Aida A Saad, Rami Bustami, Mashael Alrujaib & Khaled Alkattan
Pages: 9665-9674
Published online: 14 Nov 2019
AbstractforCancer Incidence Trends From 1999 to 2015 And Contributions Of Various Cancer Types To The Overall Burden: Projections To 2030 And Extrapolation Of Economic Burden In Saudi Arabia | Full Text | References | PDF (3.1 MB) | EPUB
  • 324 Views
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Article
Downregulated Circular RNA hsa_circ_0000291 Suppresses Migration And Proliferation Of Gastric Cancer Via Targeting The miR-183/ITGB1 Axis
Chuanwu Cao, Shilong Han, Yifeng Yuan, Yongfa Wu, Weishuai Lian, Xiaojun Zhang, Long Pan & Maoquan Li
Pages: 9675-9683
Published online: 14 Nov 2019
AbstractforDownregulated Circular RNA hsa_circ_0000291 Suppresses Migration And Proliferation Of Gastric Cancer Via Targeting The miR-183/ITGB1 Axis | Full Text | References | PDF (5.9 MB) | EPUB
  • 63 Views
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Article
The Prognosis Of Peroxiredoxin Family In Breast Cancer
Gang Wang, Wan-Chao Zhong, Yi-Hui Bi, Si-Yue Tao, Hai Zhu, Hai-Xing Zhu & A-Man Xu
Pages: 9685-9699
Published online: 14 Nov 2019
AbstractforThe Prognosis Of Peroxiredoxin Family In Breast Cancer | Full Text | References | PDF (10.1 MB) | EPUB
  • 94 Views
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Article
Overexpressed miR-122-5p Promotes Cell Viability, Proliferation, Migration And Glycolysis Of Renal Cancer By Negatively Regulating PKM2
Shuai Wang, Wei Zheng, Alin Ji, Dahong Zhang & Mi Zhou
Pages: 9701-9713
Published online: 15 Nov 2019
AbstractforOverexpressed miR-122-5p Promotes Cell Viability, Proliferation, Migration And Glycolysis Of Renal Cancer By Negatively Regulating PKM2 | Full Text | References | PDF (9.2 MB) | EPUB
  • 75 Views
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Article
Intraoperative Prediction Of Non-Sentinel Lymph Node Metastasis Based On The Molecular Assay In Breast Cancer Patients
Xiao Sun, Yan Zhang, Shuang Wu, Li Fu, Jing-Ping Yun & Yong-Sheng Wang
Pages: 9715-9723
Published online: 15 Nov 2019
AbstractforIntraoperative Prediction Of Non-Sentinel Lymph Node Metastasis Based On The Molecular Assay In Breast Cancer Patients | Full Text | References | PDF (310.3 KB) | EPUB
  • 52 Views
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Review

Review Article
Advances In Research Of Spreading Through Air Spaces And The Effects On The Prognosis Of Lung Cancer
Dandan Cao, Jun Sha, Rui Cui & Shuhua Han
Pages: 9725-9732
Published online: 15 Nov 2019
AbstractforAdvances In Research Of Spreading Through Air Spaces And The Effects On The Prognosis Of Lung Cancer | Full Text | References | PDF (848.3 KB) | EPUB
  • 76 Views
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Original Research

Article
Prognostic Value Of The Preoperative Neutrophil To Lymphocyte Ratio In Patients With Sinonasal Squamous Cell Carcinoma
Bing Zhong, Di Deng, Jin-Tao Du, Fei Chen, Ya-Feng Liu & Shi-Xi Liu
Pages: 9733-9741
Published online: 15 Nov 2019
AbstractforPrognostic Value Of The Preoperative Neutrophil To Lymphocyte Ratio In Patients With Sinonasal Squamous Cell Carcinoma | Full Text | References | PDF (1.5 MB) | EPUB
  • 62 Views
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Article
Synergistic Effect Between Full-Term Pregnancy/Breastfeeding And Familial Susceptibility On Breast Cancer Risk
Huan Lin, Jiahuai Wen, Lixia Hong, Ying Chen, Yannan Wu & Shaowen Zhong
Pages: 9743-9748
Published online: 15 Nov 2019
AbstractforSynergistic Effect Between Full-Term Pregnancy/Breastfeeding And Familial Susceptibility On Breast Cancer Risk | Full Text | References | PDF (1.4 MB) | EPUB
  • 76 Views
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Article
Reciprocal Role Of DNA Methylation And Sp1 Binding In Ki-67 Gene Transcription
Lian-Tao Li, Xun Wang, Wen-Tao Zhu, Guo-Wei Qian, Dong-Sheng Pei & Jun-Nian Zheng
Pages: 9749-9759
Published online: 18 Nov 2019
AbstractforReciprocal Role Of DNA Methylation And Sp1 Binding In Ki-67 Gene Transcription | Full Text | References | PDF (7.2 MB) | EPUB
  • 95 Views
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Article
Proton Pump Inhibitors Modulate Transport Of Doxorubicin And Its Liposomal Form Into 2D And 3D Breast Cancer Cell Cultures
Miglė Paškevičiūtė & Vilma Petrikaitė
Pages: 9761-9769
Published online: 21 Nov 2019
AbstractforProton Pump Inhibitors Modulate Transport Of Doxorubicin And Its Liposomal Form Into 2D And 3D Breast Cancer Cell Cultures | Full Text | References | PDF (6.2 MB) | EPUB
  • 73 Views
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Review

Review Article
Competing Morbidities In Advanced Head And Neck Squamous Cell Carcinoma Concurrent Chemoradiotherapy: A Strong Implication Of A Multidisciplinary Team Approach
Grazia Lazzari, Maria Assunta De Cillis, Giovanni Buccoliero & Giovanni Silvano
Pages: 9771-9782
Published online: 18 Nov 2019
AbstractforCompeting Morbidities In Advanced Head And Neck Squamous Cell Carcinoma Concurrent Chemoradiotherapy: A Strong Implication Of A Multidisciplinary Team Approach | Full Text | References | PDF (396.5 KB) | EPUB
  • 89 Views
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Original Research

Article
Low-Concentration PTX And RSL3 Inhibits Tumor Cell Growth Synergistically By Inducing Ferroptosis In Mutant p53 Hypopharyngeal Squamous Carcinoma
Jing Ye, Xiaohua Jiang, Zhihuai Dong, Sunhong Hu & Mang Xiao
Pages: 9783-9792
Published online: 20 Nov 2019
AbstractforLow-Concentration PTX And RSL3 Inhibits Tumor Cell Growth Synergistically By Inducing Ferroptosis In Mutant p53 Hypopharyngeal Squamous Carcinoma | Full Text | References | PDF (11.8 MB) | EPUB
  • 123 Views
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Article
Controlling Nutritional Status (CONUT) Score Is A Predictor Of Post-Operative Outcomes In Elderly Gastric Cancer Patients Undergoing Curative Gastrectomy: A Prospective Study
Yingpeng Huang, Yunshi Huang, Mingdong Lu, Weijian Sun, Xiangwei Sun, Xiaodong Chen, Liyi Li, Arvine Chandoo & Leping Li
Pages: 9793-9800
Published online: 18 Nov 2019
AbstractforControlling Nutritional Status (CONUT) Score Is A Predictor Of Post-Operative Outcomes In Elderly Gastric Cancer Patients Undergoing Curative Gastrectomy: A Prospective Study | Full Text | References | PDF (805.8 KB) | EPUB
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Article
Image-Guided Percutaneous ‎Microwave Ablation Versus Cryoablation For Hepatocellular Carcinoma In High-Risk Locations: Intermediate-Term Results
Jiahui Hu, Sheng Chen, Xin Wang, Ning Lin, Jianchuan Yang & Songsong Wu
Pages: 9801-9811
Published online: 18 Nov 2019
AbstractforImage-Guided Percutaneous ‎Microwave Ablation Versus Cryoablation For Hepatocellular Carcinoma In High-Risk Locations: Intermediate-Term Results | Full Text | References | PDF (3.1 MB) | EPUB
  • 77 Views
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Article
Stage-specific concurrent chemoradiotherapy with or without induction chemotherapy for locoregionally advanced nasopharyngeal carcinoma: a retrospective, population-based study
Wei-Xiong Xia, Hu Liang, Xing Lv, Lin Wang, Yan-Fang Ye, Liang-Ru Ke, Lin-Hao Xu, Xiang Guo & Yan-Qun Xiang
Pages: 9813-9827
Published online: 20 Nov 2019
AbstractforStage-specific concurrent chemoradiotherapy with or without induction chemotherapy for locoregionally advanced nasopharyngeal carcinoma: a retrospective, population-based study | Full Text | References | PDF (1.5 MB) | EPUB
  • 61 Views
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Article
Neuraxis Metastases Of Primary Central Nervous System Tumors: A Review Of Clinicopathological And Radiographic Characters Of 198 Cases In A Single Center
Hailong Liu, Junping Zhang, Yongqiang Liu, Youliang Sun, Cheng Li, Chunyu Gu, Haoran Wang, Hongwei Zhang, Chunjiang Yu & Mingshan Zhang
Pages: 9829-9841
Published online: 20 Nov 2019
AbstractforNeuraxis Metastases Of Primary Central Nervous System Tumors: A Review Of Clinicopathological And Radiographic Characters Of 198 Cases In A Single Center | Full Text | References | PDF (4.1 MB) | EPUB
  • 70 Views
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Article
Use Of Microwave Thermal Ablation In Management Of Skip Metastases In Extremity Osteosarcomas
Nan Li, Xing Wei, Zengliang Zhang & Yinglong Zhang
Pages: 9843-9848
Published online: 19 Nov 2019
AbstractforUse Of Microwave Thermal Ablation In Management Of Skip Metastases In Extremity Osteosarcomas | Full Text | References | PDF (2.5 MB) | EPUB
  • 82 Views
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Review

Review Article
Benefits Of Timely Care In Pancreatic Cancer: A Systematic Review To Navigate Through The Contradictory Evidence
Gábor Lukács, Árpád Kovács, Marcell Csanádi, Mariann Moizs, Imre Repa, Zoltán Kaló, Zoltán Vokó & János György Pitter
Pages: 9849-9861
Published online: 19 Nov 2019
AbstractforBenefits Of Timely Care In Pancreatic Cancer: A Systematic Review To Navigate Through The Contradictory Evidence | Full Text | References | PDF (968 KB) | EPUB
  • 135 Views
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Short Report

Brief Report
Efficacy And Safety Of Raltitrexed Plus Oxaliplatin-Based Transarterial Chemoembolization In Patients With Unresectable Hepatocellular Carcinoma
Wenbo Shao, Caixia Li, Jun Tang, Jinlong Song, Zixiang Li, Jize Sun, Yili Xu, Zhaomin Zheng, Jingqin Cao & Lei Zhang
Pages: 9863-9869
Published online: 19 Nov 2019
AbstractforEfficacy And Safety Of Raltitrexed Plus Oxaliplatin-Based Transarterial Chemoembolization In Patients With Unresectable Hepatocellular Carcinoma | Full Text | References | PDF (297.6 KB) | EPUB
  • 63 Views
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Original Research

Article
Lymph Node Yield Following Packet Submission After Isolation By Surgeon During Gastrectomy
Pengpeng Wang, Kecheng Zhang, Hongqing Xi, Wenquan Liang, Tianyu Xie, Yunhe Gao, Bo Wei & Lin Chen
Pages: 9871-9881
Published online: 19 Nov 2019
AbstractforLymph Node Yield Following Packet Submission After Isolation By Surgeon During Gastrectomy | Full Text | References | PDF (1.8 MB) | EPUB
  • 79 Views
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Article
Multivariate Analysis Of The Diagnostic Yield Of Conventional Bronchoscopy In Peripheral Lung Adenocarcinoma
Wei Gao, Cuiyun Li, Hui Wang, Ping Han & Yunqiang Nie
Pages: 9883-9889
Published online: 20 Nov 2019
AbstractforMultivariate Analysis Of The Diagnostic Yield Of Conventional Bronchoscopy In Peripheral Lung Adenocarcinoma | Full Text | References | PDF (232.3 KB) | EPUB
  • 52 Views
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Article
Clinicopathological Characteristics And Treatment Outcomes Of Breast Cancer Among Adolescents And Young Adults In A Developing Country
Hikmat Abdel-Razeq, Hanan Almasri, Fadwa Abdel Rahman, Hazem Abdulelah, Mahmoud Abu Nasser, Mourad Salam, Ammer Al-Dairi, Osama Natour & Dalia Rimawi
Pages: 9891-9897
Published online: 22 Nov 2019
AbstractforClinicopathological Characteristics And Treatment Outcomes Of Breast Cancer Among Adolescents And Young Adults In A Developing Country | Full Text | References | PDF (3 MB) | EPUB
  • 77 Views
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Article
Retrospective Analysis Of Comparative Outcomes In Recurrent Platinum-Sensitive Ovarian Cancer Treated With Pegylated Liposomal Doxorubicin (Lipo-Dox) And Carboplatin Versus Paclitaxel And Carboplatin
Chia-Sui Weng, Chao-Chih Wu, Tze-Chien Chen, Jen-Ruei Chen, Chueh-Yi Huang & Chih-Long Chang
Pages: 9899-9905
Published online: 21 Nov 2019
AbstractforRetrospective Analysis Of Comparative Outcomes In Recurrent Platinum-Sensitive Ovarian Cancer Treated With Pegylated Liposomal Doxorubicin (Lipo-Dox) And Carboplatin Versus Paclitaxel And Carboplatin | Full Text | References | PDF (588.1 KB) | EPUB
  • 99 Views
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Article
Downregulation of Proline Hydroxylase 2 and Upregulation of Hypoxia-Inducible Factor 1α are Associated with Endometrial Cancer Aggressiveness
Chengcheng Zhu, Huafeng Ding, Junwen Yang, Yihui Zhou, Yonghong Luo, Suhua Shi, Ying Zhang, Yalan Wei & Guantai Ni
Pages: 9907-9912
Published online: 22 Nov 2019
AbstractforDownregulation of Proline Hydroxylase 2 and Upregulation of Hypoxia-Inducible Factor 1α are Associated with Endometrial Cancer Aggressiveness | Full Text | References | PDF (4.2 MB) | EPUB
  • 63 Views
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Article
AMPH-1 As A Critical Tumor Suppressor That Inhibits Osteosarcoma Progression
Haiyun Zhang, Yujie Liu, Kehan Xu, Kai Mao, Weidong Han, Feifan Xu, Wei Wan & Yajun Sun
Pages: 9913-9919
Published online: 25 Nov 2019
AbstractforAMPH-1 As A Critical Tumor Suppressor That Inhibits Osteosarcoma Progression | Full Text | References | PDF (3.3 MB) | EPUB
  • 55 Views
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Article
Prognostic Role Of Computed Tomography Textural Features In Early-Stage Non-Small Cell Lung Cancer Patients Receiving Stereotactic Body Radiotherapy
Ran Zhang, Changbin Wang, Kai Cui, Yicong Chen, Fenghao Sun, Xiaorong Sun & Ligang Xing
Pages: 9921-9930
Published online: 25 Nov 2019
AbstractforPrognostic Role Of Computed Tomography Textural Features In Early-Stage Non-Small Cell Lung Cancer Patients Receiving Stereotactic Body Radiotherapy | Full Text | References | PDF (923.2 KB) | EPUB
  • 59 Views
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Article
Preoperative Albumin Level Is Superior To Albumin-Globulin Ratio As A Predicting Indicator In Gastric Cancer Patients Who Underwent Curative Resection
Shuao Xiao, Fan Feng, Ni Liu, Zhen Liu, Yinghao Guo, Xiao Lian & Hongwei Zhang
Pages: 9931-9938
Published online: 25 Nov 2019
AbstractforPreoperative Albumin Level Is Superior To Albumin-Globulin Ratio As A Predicting Indicator In Gastric Cancer Patients Who Underwent Curative Resection | Full Text | References | PDF (2.9 MB) | EPUB
  • 107 Views
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Article
Transarterial Chemoembolization and Sorafenib Combined with Microwave Ablation for Advanced Primary Hepatocellular Carcinoma: A Preliminary Investigation of Safety and Efficacy
Jia-Yan Ni, Hong-Liang Sun, Jiang-Hong Luo, Xiong-Ying Jiang, Dong Chen, Wei-Dong Wang, Yao-Ting Chen, Jin-Hua Huang & Lin-Feng Xu
Pages: 9939-9950
Published online: 26 Nov 2019
AbstractforTransarterial Chemoembolization and Sorafenib Combined with Microwave Ablation for Advanced Primary Hepatocellular Carcinoma: A Preliminary Investigation of Safety and Efficacy | Full Text | References | PDF (3.5 MB) | EPUB
  • 56 Views
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Article
Synchronous Neoplastic Lesions In Referred Patients With Colorectal Cancer: A Retrospective Cohort Study
Shuai Li, Kongxi Zhu, Weihua Yu, Yunxia Wang, Teng Wang, Shuang Guo, Guoxin Teng & Jianqiang Guo
Pages: 9951-9959
Published online: 26 Nov 2019
AbstractforSynchronous Neoplastic Lesions In Referred Patients With Colorectal Cancer: A Retrospective Cohort Study | Full Text | References | PDF (2 MB) | EPUB
  • 68 Views
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Article
A Novel Preoperative Nomogram for Predicting Lymph Node Invasion in Renal Cell Carcinoma Patients Without Metastasis
Pin Li, Cheng Peng, Yongpeng Xie, Lei Wang, Liangyou Gu, Shengpan Wu, Donglai Shen, Yundong Xuan, Xin Ma & Xu Zhang
Pages: 9961-9967
Published online: 26 Nov 2019
AbstractforA Novel Preoperative Nomogram for Predicting Lymph Node Invasion in Renal Cell Carcinoma Patients Without Metastasis | Full Text | References | PDF (3.2 MB) | EPUB
  • 50 Views
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Article
ENO1 Acts as a Prognostic Biomarker Candidate and Promotes Tumor Growth and Migration Ability Through the Regulation of Rab1A in Colorectal Cancer
Zhengwu Cheng, Xinyu Shao, Menglin Xu, Chunli Zhou & Junfeng Wang
Pages: 9969-9978
Published online: 26 Nov 2019
AbstractforENO1 Acts as a Prognostic Biomarker Candidate and Promotes Tumor Growth and Migration Ability Through the Regulation of Rab1A in Colorectal Cancer | Full Text | References | PDF (5.2 MB) | EPUB
  • 85 Views
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Article
Hepatic Arterial Chemoembolization With Arsenic Trioxide Eluting CalliSpheres Microspheres Versus Lipiodol Emulsion: Pharmacokinetics And Intratumoral Concentration In A Rabbit Liver Tumor Model
Xu-hua Duan, Hao Li, Jian-zhuang Ren, Xin-wei Han, Peng-fei Chen, Feng-yao Li, Guo-hao Huang & Shu-guang Ju
Pages: 9979-9988
Published online: 26 Nov 2019
AbstractforHepatic Arterial Chemoembolization With Arsenic Trioxide Eluting CalliSpheres Microspheres Versus Lipiodol Emulsion: Pharmacokinetics And Intratumoral Concentration In A Rabbit Liver Tumor Model | Full Text | References | PDF (2.9 MB) | EPUB
  • 59 Views
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Article
Perfusion, Diffusion, Or Brain Tumor Barrier Integrity: Which Represents The Glioma Features Best?
Lin-Feng Yan, Ying-Zhi Sun, Sha-Sha Zhao, Yu-Chuan Hu, Yu Han, Gang Li, Xin Zhang, Qiang Tian, Zhi-Cheng Liu, Yang Yang, Hai-Yan Nan, Ying Yu, Qian Sun, Jin Zhang, Ping Chen, Bo Hu, Fei Li, Teng-Hui Han, Wen Wang & Guang-Bin Cui
Pages: 9989-10000
Published online: 27 Nov 2019
AbstractforPerfusion, Diffusion, Or Brain Tumor Barrier Integrity: Which Represents The Glioma Features Best? | Full Text | References | PDF (6.7 MB) | EPUB
  • 71 Views
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Article
Undifferentiated Pleomorphic Sarcoma: Long-Term Follow-Up from a Large Institution
Shiqi Chen, Wending Huang, Peng Luo, Weiluo Cai, Lingge Yang, Zhengwang Sun, Biqiang Zheng, Wangjun Yan & Chunmeng Wang
Pages: 10001-10009
Published online: 27 Nov 2019
AbstractforUndifferentiated Pleomorphic Sarcoma: Long-Term Follow-Up from a Large Institution | Full Text | References | PDF (1.5 MB) | EPUB
  • 268 Views
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Article
Simvastatin Evokes An Unpredicted Antagonism For Tamoxifen In MCF-7 Breast Cancer Cells
Amel B Ibrahim, Hala F Zaki, Walaa Wadie, Mervat M Omran & Samia A Shouman
Pages: 10011-10028
Published online: 28 Nov 2019
AbstractforSimvastatin Evokes An Unpredicted Antagonism For Tamoxifen In MCF-7 Breast Cancer Cells | Full Text | References | PDF (11.6 MB) | EPUB
  • 151 Views
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Article
A Nomogram To Predict The Overall Survival Of Breast Cancer Patients And Guide The Postoperative Adjuvant Chemotherapy In China
Xin Wang, Ziwei Feng, Yubei Huang, Haixin Li, Ping Cui, Dezheng Wang, Hongji Dai, Fangfang Song, Hong Zheng, Peishan Wang, Xuchen Cao, Lin Gu, Jin Zhang, Fengju Song & Kexin Chen
Pages: 10029-10039
Published online: 28 Nov 2019
AbstractforA Nomogram To Predict The Overall Survival Of Breast Cancer Patients And Guide The Postoperative Adjuvant Chemotherapy In China | Full Text | References | PDF (5.4 MB) | EPUB
  • 60 Views
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Corrigendum

Correction
NECTIN4 Promotes Papillary Thyroid Cancer Cell Proliferation, Migration, and Invasion and Triggers EMT by Activating AKT [Corrigendum]
Page: 10041
Published online: 28 Nov 2019
CitationforNECTIN4 Promotes Papillary Thyroid Cancer Cell Proliferation, Migration, and Invasion and Triggers EMT by Activating AKT [Corrigendum] | Full Text | PDF (143.9 KB) | EPUB
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Original Research

Article
Serum Adipokines as Predictors for the Outcome of Prostate Biopsies at Early Stage Prostate Cancer Diagnosis
Ardalan E Ahmad, Aza Mohammed, Bimal Bhindi, Patrick O Richard, Kamel Fadaak, Ricardo Leão, Antonio Finelli, Neil E Fleshner & Girish S Kulkarni
Pages: 10043-10050
Published online: 29 Nov 2019
AbstractforSerum Adipokines as Predictors for the Outcome of Prostate Biopsies at Early Stage Prostate Cancer Diagnosis | Full Text | References | PDF (416.9 KB) | EPUB
  • 73 Views
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Review

Review Article
Stereotactic Radiotherapy for Parasagittal and Parafalcine Meningiomas: Patient Selection and Special Considerations
V Pinzi, L Fariselli, M Marchetti, M Scorsetti & P Navarria
Pages: 10051-10060
Published online: 29 Nov 2019
AbstractforStereotactic Radiotherapy for Parasagittal and Parafalcine Meningiomas: Patient Selection and Special Considerations | Full Text | References | PDF (457 KB) | EPUB
  • 142 Views
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Original Research

Article
STIP1 Regulates Proliferation and Migration of Lung Adenocarcinoma Through JAK2/STAT3 Signaling Pathway
Xiangjun Guo, Zhongyi Yan, Gongming Zhang, Xiang Wang, Yun Pan & Mao Huang
Pages: 10061-10072
Published online: 29 Nov 2019
AbstractforSTIP1 Regulates Proliferation and Migration of Lung Adenocarcinoma Through JAK2/STAT3 Signaling Pathway | Full Text | References | PDF (3.5 MB) | EPUB
  • 76 Views
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Article
Risk Assessment for Breast Cancer Development and Its Clinical Impact on Screening Performance in Iranian Women
Maryam Nikpour, Karimollah Hajian-Tilaki & Afsaneh Bakhtiari
Pages: 10073-10082
Published online: 29 Nov 2019
AbstractforRisk Assessment for Breast Cancer Development and Its Clinical Impact on Screening Performance in Iranian Women | Full Text | References | PDF (326.2 KB) | EPUB
  • 84 Views
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Article
Bevacizumab in Combination with Pemetrexed and Platinum Significantly Improved the Clinical Outcome of Patients with Advanced Adenocarcinoma NSCLC and Brain Metastases
Yaru Tian, Xiaoyang Zhai, Hairong Tian, Wang Jing, Hui Zhu & Jinming Yu
Pages: 10083-10092
Published online: 29 Nov 2019
AbstractforBevacizumab in Combination with Pemetrexed and Platinum Significantly Improved the Clinical Outcome of Patients with Advanced Adenocarcinoma NSCLC and Brain Metastases | Full Text | References | PDF (1.1 MB) | EPUB
  • 57 Views
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Article
SSBP1 Upregulation In Colorectal Cancer Regulates Mitochondrial Mass
Yongping Yang, Chenxi Pan, Lingyun Yu, Hongxia Ruan, Ling Chang, Jingbo Yang, Zihan Zheng, Feng Zheng & Tongjun Liu
Pages: 10093-10106
Published online: 02 Dec 2019
AbstractforSSBP1 Upregulation In Colorectal Cancer Regulates Mitochondrial Mass | Full Text | References | PDF (7.9 MB) | EPUB
  • 107 Views
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Article
PRPH2 Activates Hippo Signalling and Suppresses the Invasion and Anoikis Inhibition of Laryngeal Cancer
KaiFeng Dong, HaiTao Xue, JianGang Cheng, Jing Su, Dan Li, JiHua Zhang & HaoLei Zhang
Pages: 10107-10115
Published online: 02 Dec 2019
AbstractforPRPH2 Activates Hippo Signalling and Suppresses the Invasion and Anoikis Inhibition of Laryngeal Cancer | Full Text | References | PDF (2.2 MB) | EPUB
  • 54 Views
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Article
LncRNA miR143HG Up-Regulates p53 In Endometrial Carcinoma By Sponging miR-125a
Fan Shi, Tao Wang, Zi Liu, Yingbing Zhang, Juan Wang, Kaishuo Zhang & Jin Su
Pages: 10117-10123
Published online: 02 Dec 2019
AbstractforLncRNA miR143HG Up-Regulates p53 In Endometrial Carcinoma By Sponging miR-125a | Full Text | References | PDF (3.4 MB) | EPUB
  • 63 Views
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Article
The Effects of Matrine in Combination with Docetaxel on Castration-Resistant (Androgen-Independent) Prostate Cancer
Qi Li, Jia Xu, Zheng He, Xue Wen, Fengmei Wang, Peng Zhang, Jun Li, Bei Song, Qingyong Wang, Ronghai Li & Hai Huang
Pages: 10125-10133
Published online: 02 Dec 2019
AbstractforThe Effects of Matrine in Combination with Docetaxel on Castration-Resistant (Androgen-Independent) Prostate Cancer | Full Text | References | PDF (9 MB) | EPUB
  • 61 Views
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Article
CSNK2A1 Promotes Gastric Cancer Invasion Through the PI3K-Akt-mTOR Signaling Pathway
Chao Jiang, Zhenghong Ma, Guoan Zhang, Xigui Yang, Qin Du & Weibo Wang
Pages: 10135-10143
Published online: 02 Dec 2019
AbstractforCSNK2A1 Promotes Gastric Cancer Invasion Through the PI3K-Akt-mTOR Signaling Pathway | Full Text | References | PDF (5 MB) | EPUB
  • 109 Views
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Article
HIF1α/miR-520a-3p/AKT1/mTOR Feedback Promotes The Proliferation And Glycolysis Of Gastric Cancer Cells
Chen Pan, Qi Liu & Xiaoling Wu
Pages: 10145-10156
Published online: 02 Dec 2019
AbstractforHIF1α/miR-520a-3p/AKT1/mTOR Feedback Promotes The Proliferation And Glycolysis Of Gastric Cancer Cells | Full Text | References | PDF (9.9 MB) | EPUB
  • 89 Views
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Article
Preoperative Bilirubin Level Predicts Overall Survival and Tumor Recurrence After Resection for Perihilar Cholangiocarcinoma Patients
Chang Xian Li, Hui Zhang, Ke Wang, Xuehao Wang & Xiang Cheng Li
Pages: 10157-10165
Published online: 02 Dec 2019
AbstractforPreoperative Bilirubin Level Predicts Overall Survival and Tumor Recurrence After Resection for Perihilar Cholangiocarcinoma Patients | Full Text | References | PDF (3.5 MB) | EPUB
  • 69 Views
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Article
Comparison of Double Sleeve Lobectomy by Uniportal Video-Assisted Thoracic Surgery (VATS) and Thoracotomy for NSCLC Treatment
Liang Wu, Hao Wang, Haomin Cai, Jiang Fan, Gening Jiang, Yayi He & Lei Jiang
Pages: 10167-10174
Published online: 02 Dec 2019
AbstractforComparison of Double Sleeve Lobectomy by Uniportal Video-Assisted Thoracic Surgery (VATS) and Thoracotomy for NSCLC Treatment | Full Text | References | PDF (1.1 MB) | EPUB
  • 80 Views
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Article
Central Nervous System Involvement in Patients with Diffuse Large B Cell Lymphoma: Analysis of the Risk Factors and Prognosis from a Single-Center Retrospective Cohort Study
Jingjing Ma, Qing Li, Jie Shao, Yan Ma, Zhiguang Lin, Hui Kang & Bobin Chen
Pages: 10175-10185
Published online: 02 Dec 2019
AbstractforCentral Nervous System Involvement in Patients with Diffuse Large B Cell Lymphoma: Analysis of the Risk Factors and Prognosis from a Single-Center Retrospective Cohort Study | Full Text | References | PDF (1.6 MB) | EPUB
  • 96 Views
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Article
The Frequency of Circulating Tumour Cells and the Correlation with the Clinical Response to Standard Chemoradiotherapy in Locally Advanced Nasopharyngeal Carcinoma: A Prospective Study
Yu Qian, Yuan Wu, Zilong Yuan, Xiaohui Niu, Yaoyao He, Jun Peng, Fuxiang Zhou, Shaozhong Wei, Desheng Hu & Yunfeng Zhou
Pages: 10187-10193
Published online: 02 Dec 2019
AbstractforThe Frequency of Circulating Tumour Cells and the Correlation with the Clinical Response to Standard Chemoradiotherapy in Locally Advanced Nasopharyngeal Carcinoma: A Prospective Study | Full Text | References | PDF (1.4 MB) | EPUB
  • 55 Views
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Article
Decitabine-Containing Conditioning Regimen for Allogeneic Hematopoietic Stem Cell Transplantation in Patients with Intermediate- and High-Risk Myelodysplastic Syndrome/Acute Myeloid Leukemia: Potential Decrease in the Incidence of Acute Graft versus Host Disease
Qing Ya Wang, Yuan Li, Ze Yin Liang, Yue Yin, Wei Liu, Qian Wang, Yu Jun Dong, Yu Hua Sun, Wei Lin Xu & Han Yun Ren
Pages: 10195-10203
Published online: 04 Dec 2019
AbstractforDecitabine-Containing Conditioning Regimen for Allogeneic Hematopoietic Stem Cell Transplantation in Patients with Intermediate- and High-Risk Myelodysplastic Syndrome/Acute Myeloid Leukemia: Potential Decrease in the Incidence of Acute Graft versus Host Disease | Full Text | References | PDF (2.5 MB) | EPUB
  • 122 Views
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Article
B7-H3 Induces Ovarian Cancer Drugs Resistance Through An PI3K/AKT/BCL-2 Signaling Pathway
Li Zhou & Yangchun Zhao
Pages: 10205-10214
Published online: 03 Dec 2019
AbstractforB7-H3 Induces Ovarian Cancer Drugs Resistance Through An PI3K/AKT/BCL-2 Signaling Pathway | Full Text | References | PDF (4.9 MB) | EPUB
  • 107 Views
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Article
CircCDYL Serves as a New Biomarker in Mantle Cell Lymphoma and Promotes Cell Proliferation
Mei Mei, Yingjun Wang, Qilong Wang, Yueyao Liu, Wenting Song & Mingzhi Zhang
Pages: 10215-10221
Published online: 03 Dec 2019
AbstractforCircCDYL Serves as a New Biomarker in Mantle Cell Lymphoma and Promotes Cell Proliferation | Full Text | References | PDF (3.4 MB) | EPUB
  • 66 Views
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Article
The Role of Sharp Dissection in Nipple-Sparing Mastectomy: A Safe Procedure with No Necrosis of the Nipple-Areolar Complex
Ci-Qiu Yang, Fei Ji, Hong-Fei Gao, Liu-Lu Zhang, Mei Yang, Teng Zhu, Min-yi Chen, Jie-qing Li & Kun Wang
Pages: 10223-10228
Published online: 04 Dec 2019
AbstractforThe Role of Sharp Dissection in Nipple-Sparing Mastectomy: A Safe Procedure with No Necrosis of the Nipple-Areolar Complex | Full Text | References | PDF (540.6 KB) | EPUB
  • 71 Views
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Article
miR-194 Inhibits the Proliferation of SW620 Colon Cancer Stem Cells Through Downregulation of SSH2 Expression
Bo Sun, Yan-Tian Fang, Dan-Juan Jin, Zong-You Chen, Zhen-Yang Li, Xiao-Dong Gu & Jian-Bin Xiang
Pages: 10229-10238
Published online: 04 Dec 2019
AbstractformiR-194 Inhibits the Proliferation of SW620 Colon Cancer Stem Cells Through Downregulation of SSH2 Expression | Full Text | References | PDF (4 MB) | EPUB
  • 90 Views
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Article
Cost-Effectiveness Analysis Of EGFR Mutation Testing And Afatinib Versus Gemcitabine-Cisplatin As First-Line Therapy For Advanced Non-Small-Cell Lung Cancer In China
Ruxu You, Jinyu Liu, David Bin-Chia Wu, XinYu Qian, Boxiang Lyu, Yu Zhang & Nan Luo
Pages: 10239-10248
Published online: 05 Dec 2019
AbstractforCost-Effectiveness Analysis Of EGFR Mutation Testing And Afatinib Versus Gemcitabine-Cisplatin As First-Line Therapy For Advanced Non-Small-Cell Lung Cancer In China | Full Text | References | PDF (4.1 MB) | EPUB
  • 122 Views
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Article
Clinical Management of Risk of Radiation Pneumonia with Serum Markers During the Radiotherapy for Patients with Thoracic Malignant Tumors
Yuxia Deng, Ting Qiu, Nishant Patel, Shi Zhou, Tao Xue & Haijun Zhang
Pages: 10249-10256
Published online: 05 Dec 2019
AbstractforClinical Management of Risk of Radiation Pneumonia with Serum Markers During the Radiotherapy for Patients with Thoracic Malignant Tumors | Full Text | References | PDF (2.2 MB) | EPUB
  • 53 Views
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Article
NLRP3 Inflammasome Mediated Interleukin-1β Production in Cancer-Associated Fibroblast Contributes to ALA-PDT for Cutaneous Squamous Cell Carcinoma
Shu Nie, Xiuli Wang & Hongwei Wang
Pages: 10257-10267
Published online: 11 Dec 2019
AbstractforNLRP3 Inflammasome Mediated Interleukin-1β Production in Cancer-Associated Fibroblast Contributes to ALA-PDT for Cutaneous Squamous Cell Carcinoma | Full Text | References | PDF (7.5 MB) | EPUB
  • 82 Views
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Article
Head and Eye Trauma Before Retinoblastoma Diagnosis
Rongxin Chen, Huijing Ye, Shu Liu, Yueyan Lin, Wei Xiao, Shaowei Bi, Guo Chen, Te Zhang, Jingqiao Chen & Huasheng Yang
Pages: 10269-10274
Published online: 06 Dec 2019
AbstractforHead and Eye Trauma Before Retinoblastoma Diagnosis | Full Text | References | PDF (1.9 MB) | EPUB
  • 75 Views
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Article
ATG3, a Target of miR-431-5p, Promotes Proliferation and Invasion of Colon Cancer via Promoting Autophagy
Wei Huang, Chong Zeng, Shanbiao Hu, Lei Wang & Jie Liu
Pages: 10275-10285
Published online: 09 Dec 2019
AbstractforATG3, a Target of miR-431-5p, Promotes Proliferation and Invasion of Colon Cancer via Promoting Autophagy | Full Text | References | PDF (8.9 MB) | EPUB
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Article
CXCR7, a Prognostic Biomarker in Cervical Squamous Cell Carcinoma, May Be a Screening Index for Treatment Options at Stages IB1 and IIA1
Danyang Zhao, Wenban Qin, Chuanxiang Zhao, Jianxiong Long & Mujun Li
Pages: 10287-10296
Published online: 09 Dec 2019
AbstractforCXCR7, a Prognostic Biomarker in Cervical Squamous Cell Carcinoma, May Be a Screening Index for Treatment Options at Stages IB1 and IIA1 | Full Text | References | PDF (7.7 MB) | EPUB
  • 57 Views
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Article
Validation of the Chinese Version of the Shame and Stigma Scale in Patients with Head and Neck Cancer
Wei-Ting Tseng, Yu Lee, Chi-Fa Hung, Pao-Yen Lin, Chih-Yen Chien, Hui-Ching Chuang, Fu-Min Fang, Shau-Hsuan Li, Tai-Lin Huang, Mian-Yoon Chong & Liang-Jen Wang
Pages: 10297-10305
Published online: 09 Dec 2019
AbstractforValidation of the Chinese Version of the Shame and Stigma Scale in Patients with Head and Neck Cancer | Full Text | References | PDF (477.7 KB) | EPUB
  • 152 Views
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Article
Cervical Cancer Cells-Secreted Exosomal microRNA-221-3p Promotes Invasion, Migration and Angiogenesis of Microvascular Endothelial Cells in Cervical Cancer by Down-Regulating MAPK10 Expression
Lu Zhang, Huihui Li, Ming Yuan, Mingbao Li & Shuquan Zhang
Pages: 10307-10319
Published online: 09 Dec 2019
AbstractforCervical Cancer Cells-Secreted Exosomal microRNA-221-3p Promotes Invasion, Migration and Angiogenesis of Microvascular Endothelial Cells in Cervical Cancer by Down-Regulating MAPK10 Expression | Full Text | References | PDF (7.7 MB) | EPUB
  • 120 Views
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Case Report

Case Report
Spinal Intramedullary Solitary Fibrous Tumor: A Rare and Challenging Diagnosis
Chenlong Yang, Yulun Xu & Xiaoguang Liu
Pages: 10321-10326
Published online: 10 Dec 2019
AbstractforSpinal Intramedullary Solitary Fibrous Tumor: A Rare and Challenging Diagnosis | Full Text | References | PDF (655.6 KB) | EPUB
  • 58 Views
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Review

Review Article
Overview of microRNA-199a Regulation in Cancer
Qiwen Wang, Bingyu Ye, Ping Wang, Fenjie Yao, Chunyan Zhang & Guoying Yu
Pages: 10327-10335
Published online: 10 Dec 2019
AbstractforOverview of microRNA-199a Regulation in Cancer | Full Text | References | PDF (441.4 KB) | EPUB
  • 216 Views
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Original Research

Article
Lack of Efficacy: When Opioids Do Not Achieve Analgesia from the Beginning of Treatment in Cancer Patients
Oscar Corli, Giovanna Damia, Francesca Galli, Carmen Verrastro & Massimo Broggini
Pages: 10337-10344
Published online: 10 Dec 2019
AbstractforLack of Efficacy: When Opioids Do Not Achieve Analgesia from the Beginning of Treatment in Cancer Patients | Full Text | References | PDF (356.6 KB) | EPUB
  • 72 Views
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Article
A Novel lncRNA MYOSLID/miR-1286/RAB13 Axis Plays a Critical Role in Osteosarcoma Progression
Shouhang Yang, Ming Chen & Chuanfu Lin
Pages: 10345-10351
Published online: 10 Dec 2019
AbstractforA Novel lncRNA MYOSLID/miR-1286/RAB13 Axis Plays a Critical Role in Osteosarcoma Progression | Full Text | References | PDF (5.1 MB) | EPUB
  • 54 Views
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Review

Review Article
Decision of Adjuvant Systemic Treatment in HR+ HER2- Early Invasive Breast Cancer: Which Biomarkers Could Help?
Marie Alexandre, Aurélie Maran-Gonzalez, Marie Viala, Nelly Firmin, Véronique D’Hondt, Marian Gutowski, Céline Bourgier, William Jacot & Séverine Guiu
Pages: 10353-10373
Published online: 11 Dec 2019
AbstractforDecision of Adjuvant Systemic Treatment in HR+ HER2- Early Invasive Breast Cancer: Which Biomarkers Could Help? | Full Text | References | PDF (533.1 KB) | EPUB
  • 89 Views
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Original Research

Article
Combined Use of Mean Platelet Volume/Platelet Count Ratio and Platelet Distribution Width to Distinguish Between Patients with Nasopharyngeal Carcinoma, Those with Benign Tumors of the Nasopharynx, and Healthy Subjects
Xuan Zhang, Yuan-yuan Qin, Min Chen, Yang-yang Wu & Fa-quan Lin
Pages: 10375-10382
Published online: 11 Dec 2019
AbstractforCombined Use of Mean Platelet Volume/Platelet Count Ratio and Platelet Distribution Width to Distinguish Between Patients with Nasopharyngeal Carcinoma, Those with Benign Tumors of the Nasopharynx, and Healthy Subjects | Full Text | References | PDF (3.8 MB) | EPUB
  • 62 Views
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Article
The Value of DNA Quantitative Cytology Test for the Screening of Endometrial Cancer
Bao-hua Yang, Ming-xia Yu, Jun Xu, Yan Su & Zhi-hong Ai
Pages: 10383-10391
Published online: 11 Dec 2019
AbstractforThe Value of DNA Quantitative Cytology Test for the Screening of Endometrial Cancer | Full Text | References | PDF (4.4 MB) | EPUB
  • 64 Views
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Article
LncRNA PTCSC3 Inhibits Tumor Growth and Cancer Cell Stemness in Gastric Cancer by Interacting with lncRNA Linc-pint
Lei Hong, Haijuan Wang, Junyan Wang, Suju Wei, Fan Zhang, Jing Han, Yan Liu, Minting Ma, Chengyuan Liu, Yu Xu & Da Jiang
Pages: 10393-10399
Published online: 11 Dec 2019
AbstractforLncRNA PTCSC3 Inhibits Tumor Growth and Cancer Cell Stemness in Gastric Cancer by Interacting with lncRNA Linc-pint | Full Text | References | PDF (5.2 MB) | EPUB
  • 103 Views
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Article
The Characteristics and Survival of Patients with Mesorectum Metastatic Lymph Nodes from Cervical Cancer
Weiping Wang, Xiaoliang Liu, Fuquan Zhang & Ke Hu
Pages: 10401-10408
Published online: 11 Dec 2019
AbstractforThe Characteristics and Survival of Patients with Mesorectum Metastatic Lymph Nodes from Cervical Cancer | Full Text | References | PDF (1.1 MB) | EPUB
  • 58 Views
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Corrigendum

Correction
Stanniocalcin 2 (STC2) Expression Promotes Post-Radiation Survival, Migration and Invasion of Nasopharyngeal Carcinoma Cells [Corrigendum]
Page: 10409
Published online: 11 Dec 2019
CitationforStanniocalcin 2 (STC2) Expression Promotes Post-Radiation Survival, Migration and Invasion of Nasopharyngeal Carcinoma Cells [Corrigendum] | Full Text | PDF (1.5 MB) | EPUB
  • 43 Views
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Review

Review Article
MiR-326: Promising Biomarker for Cancer
Yao-Jie Pan, Jian Wan & Chun-Bin Wang
Pages: 10411-10418
Published online: 11 Dec 2019
AbstractforMiR-326: Promising Biomarker for Cancer | Full Text | References | PDF (306.5 KB) | EPUB
  • 105 Views
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Original Research

Article
Cost-Effectiveness Analysis of First-Line Cetuximab Plus Leucovorin, Fluorouracil, and Oxaliplatin (FOLFOX-4) versus FOLFOX-4 in Patients with RAS Wild-Type Metastatic Colorectal Cancer
Liangliang Bai, Pengfei Zhang, Kexun Zhou, Weiting Liao & Qiu Li
Pages: 10419-10426
Published online: 12 Dec 2019
AbstractforCost-Effectiveness Analysis of First-Line Cetuximab Plus Leucovorin, Fluorouracil, and Oxaliplatin (FOLFOX-4) versus FOLFOX-4 in Patients with RAS Wild-Type Metastatic Colorectal Cancer | Full Text | References | PDF (1.2 MB) | EPUB
  • 83 Views
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Article
First-Line Doublet Chemotherapy for Metastatic Triple-Negative Breast Cancer: Circulating Tumor Cell Analysis of the tnAcity Trial
Minetta C Liu, Wolfgang Janni, Vassilis Georgoulias, Denise A Yardley, Nadia Harbeck, Xin Wei, Desmond McGovern & Robert Beck
Pages: 10427-10433
Published online: 12 Dec 2019
AbstractforFirst-Line Doublet Chemotherapy for Metastatic Triple-Negative Breast Cancer: Circulating Tumor Cell Analysis of the tnAcity Trial | Full Text | References | PDF (419.3 KB) | EPUB
  • 66 Views
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Article
Suppressed Expression of CXCL14 in Hepatocellular Carcinoma Tissues and Its Reduction in the Advanced Stage of Chronic HBV Infection
Yong Lin, Bo-Mei Chen, Xiao-Lu Yu, Huo-Chun Yi, Jian-Jun Niu & Shu-Lian Li
Pages: 10435-10443
Published online: 12 Dec 2019
AbstractforSuppressed Expression of CXCL14 in Hepatocellular Carcinoma Tissues and Its Reduction in the Advanced Stage of Chronic HBV Infection | Full Text | References | PDF (1.2 MB) | EPUB
  • 59 Views
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Article
Three-Dimensional CT Texture Analysis to Differentiate Colorectal Signet-Ring Cell Carcinoma and Adenocarcinoma
Yali Yue, Feixiang Hu, Tingdan Hu, Yiqun Sun, Tong Tong & Yajia Gu
Pages: 10445-10453
Published online: 13 Dec 2019
AbstractforThree-Dimensional CT Texture Analysis to Differentiate Colorectal Signet-Ring Cell Carcinoma and Adenocarcinoma | Full Text | References | PDF (6.5 MB) | EPUB
  • 57 Views
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Article
Long Non-Coding RNA HCP5 Facilitates Cell Invasion And Epithelial-Mesenchymal Transition In Oral Squamous Cell Carcinoma By miR-140-5p/SOX4 Axis
Jianling Zhao, Xijing Bai, Chong Feng, Xinhua Shang & Yuli Xi
Pages: 10455-10462
Published online: 12 Dec 2019
AbstractforLong Non-Coding RNA HCP5 Facilitates Cell Invasion And Epithelial-Mesenchymal Transition In Oral Squamous Cell Carcinoma By miR-140-5p/SOX4 Axis | Full Text | References | PDF (5.1 MB) | EPUB
  • 56 Views
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Article
First-In-Human Phase I Study Of A Dual mTOR Kinase And DNA-PK Inhibitor (CC-115) In Advanced Malignancy
Pamela Munster, Monica Mita, Amit Mahipal, John Nemunaitis, Christophe Massard, Tom Mikkelsen, Cristina Cruz, Luis Paz-Ares, Manuel Hidalgo, Dana Rathkopf, George Blumenschein Jr, David C Smith, Barbara Eichhorst, Tim Cloughesy, Ellen H Filvaroff, Shaoyi Li, Heather Raymon, Hans de Haan, Kristen Hege & Johanna C Bendell
Pages: 10463-10476
Published online: 13 Dec 2019
AbstractforFirst-In-Human Phase I Study Of A Dual mTOR Kinase And DNA-PK Inhibitor (CC-115) In Advanced Malignancy | Full Text | References | PDF (2.8 MB) | EPUB
  • 129 Views
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Review

Review Article
CDH1 (E-Cadherin) Mutation and Gastric Cancer: Genetics, Molecular Mechanisms and Guidelines for Management
Santosh Shenoy
Pages: 10477-10486
Published online: 13 Dec 2019
AbstractforCDH1 (E-Cadherin) Mutation and Gastric Cancer: Genetics, Molecular Mechanisms and Guidelines for Management | Full Text | References | PDF (1.8 MB) | EPUB
  • 430 Views
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Original Research

Article
Prediction of Overall Survival of Patients with Completely Resected Non-Small Cell Lung Cancer: Analyses of Preoperative Spirometry, Preoperative Blood Tests, and Other Clinicopathological Data
Mengkun Shi, Cheng Zhan, Jialun Shi & Qun Wang
Pages: 10487-10497
Published online: 13 Dec 2019
AbstractforPrediction of Overall Survival of Patients with Completely Resected Non-Small Cell Lung Cancer: Analyses of Preoperative Spirometry, Preoperative Blood Tests, and Other Clinicopathological Data | Full Text | References | PDF (2.9 MB) | EPUB
  • 62 Views
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Article
RETRACTED ARTICLE: Oxymatrine Inhibits the Proliferation and Invasion of Breast Cancer Cells via the PI3K Pathway
Lin Guo & Tengfei Yang
Pages: 10499-10508
Published online: 13 Dec 2019
AbstractforRETRACTED ARTICLE: Oxymatrine Inhibits the Proliferation and Invasion of Breast Cancer Cells via the PI3K Pathway | PDF (8.3 MB)
  • 18 Views
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Review

Review Article
Current Understanding of Circular RNAs in Gastric Cancer
Xiaohuan Tang, Jiaming Zhu, Yuanda Liu, Chao Chen, Tianzhou Liu & Jingjing Liu
Pages: 10509-10521
Published online: 13 Dec 2019
AbstractforCurrent Understanding of Circular RNAs in Gastric Cancer | Full Text | References | PDF (1.5 MB) | EPUB
  • 82 Views
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Original Research

Article
LncRNA TP73-AS1 Activates TGF-β1 to Promote the Migration and Invasion of Colorectal Cancer Cell
Mingli Li, Yuanyuan Jin & Yuanzhi Li
Pages: 10523-10529
Published online: 16 Dec 2019
AbstractforLncRNA TP73-AS1 Activates TGF-β1 to Promote the Migration and Invasion of Colorectal Cancer Cell | Full Text | References | PDF (5.1 MB) | EPUB
  • 56 Views
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Article
Downregulation of lncRNA NCK1-AS1 Inhibits Cancer Cell Migration and Invasion in Nasopharyngeal Carcinoma by Upregulating miR-135a
Haili Hu, Haixia Li & Xiao Feng
Pages: 10531-10537
Published online: 17 Dec 2019
AbstractforDownregulation of lncRNA NCK1-AS1 Inhibits Cancer Cell Migration and Invasion in Nasopharyngeal Carcinoma by Upregulating miR-135a | Full Text | References | PDF (4.3 MB) | EPUB
  • 70 Views
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Article
GALE Promotes the Proliferation and Migration of Glioblastoma Cells and Is Regulated by miR-let-7i-5p
Xiaopeng Sun, Hao Xue, Ye Xiong, Rui Yu, Xiao Gao, Mingyu Qian, Shaobo Wang, Huizhi Wang, Jianye Xu, Zihang Chen, Lin Deng & Gang Li
Pages: 10539-10554
Published online: 16 Dec 2019
AbstractforGALE Promotes the Proliferation and Migration of Glioblastoma Cells and Is Regulated by miR-let-7i-5p | Full Text | References | PDF (14.8 MB) | EPUB
  • 103 Views
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Article
Serum Dickopff 1 as a Novel Biomarker in Hepatocellular Carcinoma Diagnosis and Follow Up After Ablative Therapy
Yehia Sadek Younis, Hatem Samir Alegaily, Waleed Elagawy, Atteyat Aboelmaged Semeya, Yousry Esam-Eldin Abo-Amer, Mohamed El-Abgeegy, Sahar Mohamed Mostafa, Heba Fadl Elsergany & Sherief Abd-Elsalam
Pages: 10555-10562
Published online: 17 Dec 2019
AbstractforSerum Dickopff 1 as a Novel Biomarker in Hepatocellular Carcinoma Diagnosis and Follow Up After Ablative Therapy | Full Text | References | PDF (349.7 KB) | EPUB
  • 69 Views
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Article
Dynamic Changes Of Body Image And Quality Of Life In Breast Cancer Patients
Tzu-Yi Wu, Tsai-Wang Chang, Sheng-Mao Chang, Yun-Ying Lin, Jung-Der Wang & Yao-Lung Kuo
Pages: 10563-10571
Published online: 17 Dec 2019
AbstractforDynamic Changes Of Body Image And Quality Of Life In Breast Cancer Patients | Full Text | References | PDF (2.9 MB) | EPUB
  • 321 Views
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Article
Metastasectomy Improves the Survival of Gastric Cancer Patients with Krukenberg Tumors: A Retrospective Analysis of 182 patients
Fuhai Ma, Yang Li, Weikun Li, Wenzhe Kang, Hao Liu, Shuai Ma, Yibin Xie, Yuxin Zhong, Quan Xu, Bingzhi Wang, Liyan Xue & Yantao Tian
Pages: 10573-10580
Published online: 18 Dec 2019
AbstractforMetastasectomy Improves the Survival of Gastric Cancer Patients with Krukenberg Tumors: A Retrospective Analysis of 182 patients | Full Text | References | PDF (1.9 MB) | EPUB
  • 78 Views
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Article
Decreased expression of miR-410-3p correlates with poor prognosis and tumorigenesis in human glioma
Chaojia Wang, Shulan Huang, Shanshan Rao, Juntao Hu, Yuqiang Zhang, Jie Luo & Hui Wang
Pages: 10581-10592
Published online: 18 Dec 2019
AbstractforDecreased expression of miR-410-3p correlates with poor prognosis and tumorigenesis in human glioma | Full Text | References | PDF (3.8 MB) | EPUB
  • 60 Views
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Article
Risk Factors of Deterioration in Quality of Life Scores in Thyroid Cancer Patients After Thyroidectomy
Jie Li, Ling Bo Xue, Xiao Yi Gong, Yan Fang Yang, Bu Yong Zhang, Jian Jin, Qing Feng Shi & Yong Hong Liu
Pages: 10593-10598
Published online: 19 Dec 2019
AbstractforRisk Factors of Deterioration in Quality of Life Scores in Thyroid Cancer Patients After Thyroidectomy | Full Text | References | PDF (338.5 KB) | EPUB
  • 122 Views
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Article
miR-503 Inhibits Proliferation, Migration, And Angiogenesis Of Glioma By Acting On VEGFA Through Targeting LRIG2
Sheng-Li Sun, Yu-Gao Shu & Mei-Yi Tao
Pages: 10599-10608
Published online: 19 Dec 2019
AbstractformiR-503 Inhibits Proliferation, Migration, And Angiogenesis Of Glioma By Acting On VEGFA Through Targeting LRIG2 | Full Text | References | PDF (7.4 MB) | EPUB
  • 86 Views
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Article
Baohuoside I Inhibits the Proliferation of Pancreatic Cancer Cells via mTOR/S6K1-Caspases/Bcl2/Bax Apoptotic Signaling
Fubiao Ni, Hengjie Tang, Cheng Wang, Hewei Zhang, Chenlei Zheng, Ning Zhang, Bicheng Chen & Linxiao Sun
Pages: 10609-10621
Published online: 19 Dec 2019
AbstractforBaohuoside I Inhibits the Proliferation of Pancreatic Cancer Cells via mTOR/S6K1-Caspases/Bcl2/Bax Apoptotic Signaling | Full Text | References | PDF (11.7 MB) | EPUB
  • 89 Views
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Article
High Inflammatory Factor Grading Predicts Poor Disease-Free Survival in AJCC Stage I-II Hepatocellular Carcinoma Patients After R0 Resection
Mao Zhang, Mei-Sze Chua, Jie Hu, Haoran Li, Shun Zhang, Liqun Wu & Bing Han
Pages: 10623-10632
Published online: 19 Dec 2019
AbstractforHigh Inflammatory Factor Grading Predicts Poor Disease-Free Survival in AJCC Stage I-II Hepatocellular Carcinoma Patients After R0 Resection | Full Text | References | PDF (3.2 MB) | EPUB
  • 53 Views
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Article
LncRNA FOXD2-AS1 Regulates miR-25-3p/Sema4c Axis To Promote The Invasion And Migration Of Colorectal Cancer Cells
Mengyan Zhang, Xiang Jiang, Sumei Jiang, Zhongying Guo, Qinfeng Zhou & Jingdong He
Pages: 10633-10639
Published online: 19 Dec 2019
AbstractforLncRNA FOXD2-AS1 Regulates miR-25-3p/Sema4c Axis To Promote The Invasion And Migration Of Colorectal Cancer Cells | Full Text | References | PDF (3.5 MB) | EPUB
  • 52 Views
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Article
A Novel Scoring System for Patients with Recurrence of Hepatocellular Carcinoma After Undergoing Minimal Invasive Therapies
Qi Wang, Liang Ma, Jianjun Li, Chunwang Yuan, Jianping Sun, Kang Li, Ling Qin, Chaoran Zang, Yanan Zhao, Yan Zhao & Yonghong Zhang
Pages: 10641-10649
Published online: 20 Dec 2019
AbstractforA Novel Scoring System for Patients with Recurrence of Hepatocellular Carcinoma After Undergoing Minimal Invasive Therapies | Full Text | References | PDF (4.7 MB) | EPUB
  • 53 Views
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Article
Amyloid Beta (A4) Precursor Protein: A Potential Biomarker for Recurrent Nasopharyngeal Carcinoma
Xiao-Yu Li, Hui-Ling Meng, Kai-Guo Li, Xiao-Hui Yang, Xiao-Dong Zhu, Ling Li, Zhong-Guo Liang, Xin-Bin Pan, Fan-Yan Zeng & Song Qu
Pages: 10651-10656
Published online: 20 Dec 2019
AbstractforAmyloid Beta (A4) Precursor Protein: A Potential Biomarker for Recurrent Nasopharyngeal Carcinoma | Full Text | References | PDF (2.5 MB) | EPUB
  • 55 Views
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Article
lncRNA DGCR5 Up-Regulates TGF-β1, Increases Cancer Cell Stemness and Predicts Survival of Prostate Cancer Patients
Bin Li, Zhirui Guo, Quan Liang, Huiling Zhou, Yanping Luo, Shuyun He & Zhe Lin
Pages: 10657-10663
Published online: 23 Dec 2019
AbstractforlncRNA DGCR5 Up-Regulates TGF-β1, Increases Cancer Cell Stemness and Predicts Survival of Prostate Cancer Patients | Full Text | References | PDF (4.6 MB) | EPUB
  • 60 Views
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Article
The Personalized Shoulder Reconstruction Assisted by 3D Printing Technology After Resection of the Proximal Humerus Tumours
Hongzhi Hu, Weijian Liu, Qianwen Zeng, Shangyu Wang, Zhicai Zhang, Jianxiang Liu, Yingze Zhang, Zengwu Shao & Baichuan Wang
Pages: 10665-10673
Published online: 23 Dec 2019
AbstractforThe Personalized Shoulder Reconstruction Assisted by 3D Printing Technology After Resection of the Proximal Humerus Tumours | Full Text | References | PDF (1.5 MB) | EPUB
  • 143 Views
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Article
MMP-2, MMP-9, TIMP-1, and TIMP-2 in the Peripheral Blood of Patients with Differentiated Thyroid Carcinoma
Wen-jing Zhang, Bing Song & Tao Yang
Pages: 10675-10681
Published online: 23 Dec 2019
AbstractforMMP-2, MMP-9, TIMP-1, and TIMP-2 in the Peripheral Blood of Patients with Differentiated Thyroid Carcinoma | Full Text | References | PDF (1.7 MB) | EPUB
  • 118 Views
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Erratum

Correction
L61H46 Shows Potent Efficacy Against Human Pancreatic Cancer Through Inhibiting STAT3 Pathway [Erratum]
Pages: 10683-10684
Published online: 23 Dec 2019
CitationforL61H46 Shows Potent Efficacy Against Human Pancreatic Cancer Through Inhibiting STAT3 Pathway [Erratum] | Full Text | PDF (1.3 MB) | EPUB
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Original Research

Article
A Novel Prognostic Scoring Model Based on Albumin and γ-Glutamyltransferase for Hepatocellular Carcinoma Prognosis
Liguang Wang, Qun Li, Jie Zhang & Jun Lu
Pages: 10685-10694
Published online: 23 Dec 2019
AbstractforA Novel Prognostic Scoring Model Based on Albumin and γ-Glutamyltransferase for Hepatocellular Carcinoma Prognosis | Full Text | References | PDF (2.6 MB) | EPUB
  • 59 Views
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Article
Comparison of Microwave Ablation and Transarterial Chemoembolization for Single-Nodule Hepatocellular Carcinoma Smaller Than 5cm: A Propensity Score Matching Analysis
Rui Cui, Xiao-hui Wang, Chao Ma, Tong Liu, Zhi-gang Cheng, Zhi-yu Han, Fang-yi Liu, Xiao-ling Yu, Jie Yu & Ping Liang
Pages: 10695-10704
Published online: 23 Dec 2019
AbstractforComparison of Microwave Ablation and Transarterial Chemoembolization for Single-Nodule Hepatocellular Carcinoma Smaller Than 5cm: A Propensity Score Matching Analysis | Full Text | References | PDF (4.8 MB) | EPUB
  • 57 Views
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Article
Super-Enhancer-Associated Hub Genes In Chronic Myeloid Leukemia Identified Using Weighted Gene Co-Expression Network Analysis
Hongying Ma, Jian Qu, Jian Luo, Tingting Qi, Huanmiao Tan, Zhaohui Jiang, Haiwen Zhang & Qiang Qu
Pages: 10705-10718
Published online: 23 Dec 2019
AbstractforSuper-Enhancer-Associated Hub Genes In Chronic Myeloid Leukemia Identified Using Weighted Gene Co-Expression Network Analysis | Full Text | References | PDF (9.3 MB) | EPUB
  • 118 Views
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Article
Downregulation of CDH16 in Papillary Thyroid Cancer and Its Potential Molecular Mechanism Analysed by qRT-PCR, TCGA and in silico Analysis
Pihong Li, Qiaolin Wu, Yihan Sun, Xiaoyu Pan, Yifan Han, Bing Ye, Yinlong Zhang, Jianda Dong & Zhouci Zheng
Pages: 10719-10729
Published online: 23 Dec 2019
AbstractforDownregulation of CDH16 in Papillary Thyroid Cancer and Its Potential Molecular Mechanism Analysed by qRT-PCR, TCGA and in silico Analysis | Full Text | References | PDF (6.5 MB) | EPUB
  • 67 Views
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Review

Review Article
T-Regulatory Cells In Tumor Progression And Therapy
Amit Verma, Rohit Mathur, Abdullah Farooque, Vandana Kaul, Seema Gupta & Bilikere S Dwarakanath
Pages: 10731-10747
Published online: 24 Dec 2019
AbstractforT-Regulatory Cells In Tumor Progression And Therapy | Full Text | References | PDF (3.5 MB) | EPUB
  • 122 Views
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Original Research

Article
Clinicopathological Characteristics and Survival of Small Cell Carcinoma of the Salivary Gland: a Population-Based Study
Jinbo Bai, Fen Zhao & Shuang Pan
Pages: 10749-10757
Published online: 24 Dec 2019
AbstractforClinicopathological Characteristics and Survival of Small Cell Carcinoma of the Salivary Gland: a Population-Based Study | Full Text | References | PDF (2.8 MB) | EPUB
  • 61 Views
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Case Report

Case Report
Malignant Triton Tumor in a Child: Case Report and Literature Review
Ailing Zhao, Daling Ding, Xueqin Li & Jiangtao Wang
Pages: 10759-10766
Published online: 24 Dec 2019
AbstractforMalignant Triton Tumor in a Child: Case Report and Literature Review | Full Text | References | PDF (2.9 MB) | EPUB
  • 92 Views
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Original Research

Article
Thoracic Radiotherapy Benefits Elderly Extensive-Stage Small Cell Lung Cancer Patients with Distant Metastasis
Jing Qi, Liming Xu, Jian Sun, Xin Wang & Lujun Zhao
Pages: 10767-10775
Published online: 24 Dec 2019
AbstractforThoracic Radiotherapy Benefits Elderly Extensive-Stage Small Cell Lung Cancer Patients with Distant Metastasis | Full Text | References | PDF (1.2 MB) | EPUB
  • 60 Views
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Review

Review Article
Beyond Ruxolitinib: Fedratinib and Other Emergent Treatment Options for Myelofibrosis
Jan Philipp Bewersdorf, Sara Mohamed Jaszczur, Salma Afifi, Jennifer C Zhao & Amer M Zeidan
Pages: 10777-10790
Published online: 24 Dec 2019
AbstractforBeyond Ruxolitinib: Fedratinib and Other Emergent Treatment Options for Myelofibrosis | Full Text | References | PDF (526.2 KB) | EPUB
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Original Research

Article
Increased Stromal Infiltrating Lymphocytes are Associated with Circulating Tumor Cells and Metastatic Relapse in Breast Cancer Patients After Neoadjuvant Chemotherapy
Jiawei Liu, Yan Xu, Muxin Yu, Zhao Liu, Yi Xu, Ge Ma, Wenbin Zhou, Peng Kong, Lijun Ling, Shui Wang, Hong Pan & Yi Zhao
Pages: 10791-10800
Published online: 27 Dec 2019
AbstractforIncreased Stromal Infiltrating Lymphocytes are Associated with Circulating Tumor Cells and Metastatic Relapse in Breast Cancer Patients After Neoadjuvant Chemotherapy | Full Text | References | PDF (2.5 MB) | EPUB
  • 71 Views
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Case Report

Case Report
A Case with Rectal Cancer Relapses After Clinical Complete Remission Following Neoadjuvant Chemoradiotherapy
Ping-Bao Zhang, Zi-Li Huang, Jia-Bei Li & Xiu-Yan Huang
Pages: 10801-10806
Published online: 27 Dec 2019
AbstractforA Case with Rectal Cancer Relapses After Clinical Complete Remission Following Neoadjuvant Chemoradiotherapy | Full Text | References | PDF (912.8 KB) | EPUB
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Original Research

Article
Long Non-Coding RNA LINC00511 Mediates the Effects of ESR1 on Proliferation and Invasion of Ovarian Cancer Through miR-424-5p and miR-370-5p
Kang Wang, Genhai Zhu, Shan Bao & Shiling Chen
Pages: 10807-10819
Published online: 27 Dec 2019
AbstractforLong Non-Coding RNA LINC00511 Mediates the Effects of ESR1 on Proliferation and Invasion of Ovarian Cancer Through miR-424-5p and miR-370-5p | Full Text | References | PDF (8.7 MB) | EPUB
  • 86 Views
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Article
Potential Antiangiogenic Treatment Eligibility of Patients with Squamous Non-Small–Cell Lung Cancer: EPISQUAMAB Study (GFPC 2015-01)
Alain Vergnenègre, Victor Basse, Gwenaelle Le Garff, Olivier Bylicki, Catherine Dubos-Arvis, Bénédicte Comet, Marie Marcq, Jacques Le Treut, Jean-Bernard Auliac, Anne Madroszyk, Gislaine Fraboulet, Jacky Crequit, Pascal Thomas, Nicolas Paleiron, Isabelle Monnet & On behalf of the French Lung Cancer Group
Pages: 10821-10826
Published online: 27 Dec 2019
AbstractforPotential Antiangiogenic Treatment Eligibility of Patients with Squamous Non-Small–Cell Lung Cancer: EPISQUAMAB Study (GFPC 2015-01) | Full Text | References | PDF (538.7 KB) | EPUB
  • 61 Views
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Article
Development and Validation of Nomograms for Predicting the Prognosis of Triple-Negative Breast Cancer Patients Based on 379 Chinese Patients
Hao Shi, Xiao-Hui Wang, Jun-Wei Gu & Gui-Long Guo
Pages: 10827-10839
Published online: 30 Dec 2019
AbstractforDevelopment and Validation of Nomograms for Predicting the Prognosis of Triple-Negative Breast Cancer Patients Based on 379 Chinese Patients | Full Text | References | PDF (8.1 MB) | EPUB
  • 84 Views
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Article
LncRNA PCAT-1 Promoted ESCC Progression via Regulating ANXA10 Expression by Sponging miR-508-3p
Bao Zang, Jianqiang Zhao & Chen Chen
Pages: 10841-10849
Published online: 30 Dec 2019
AbstractforLncRNA PCAT-1 Promoted ESCC Progression via Regulating ANXA10 Expression by Sponging miR-508-3p | Full Text | References | PDF (6.3 MB) | EPUB
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Review

Review Article
Application of Radiomics for Personalized Treatment of Cancer Patients
Yiming Meng, Jing Sun, Na Qu, Guirong Zhang, Tao Yu & Haozhe Piao
Pages: 10851-10858
Published online: 30 Dec 2019
AbstractforApplication of Radiomics for Personalized Treatment of Cancer Patients | Full Text | References | PDF (333 KB) | EPUB
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Original Research

Article
Long Intergenic Non-Coding RNA 01121 Promotes Breast Cancer Cell Proliferation, Migration, and Invasion via the miR-150-5p/HMGA2 Axis
Zhuolu Wang, Pinghu Wang, Lin Cao, Fucheng Li, Shenjia Duan, Guorong Yuan, Lixin Xiao, Lin Guo, Hong Yin, Duying Xie, Jing Zhu, Xingchu Chen & Mengqi Zhang
Pages: 10859-10870
Published online: 30 Dec 2019
AbstractforLong Intergenic Non-Coding RNA 01121 Promotes Breast Cancer Cell Proliferation, Migration, and Invasion via the miR-150-5p/HMGA2 Axis | Full Text | References | PDF (4.4 MB) | EPUB
  • 101 Views
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Review

Review Article
The Significance of Adjuvant Therapy for Extrahepatic Cholangiocarcinoma After Surgery
Gaoyuan Wang, Qiang Wang, Xia Fan, Lijuan Ding & Lihua Dong
Pages: 10871-10882
Published online: 30 Dec 2019
AbstractforThe Significance of Adjuvant Therapy for Extrahepatic Cholangiocarcinoma After Surgery | Full Text | References | PDF (307.7 KB) | EPUB
  • 63 Views
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Original Research

Article
Silencing of Peroxiredoxin 1 Inhibits the Proliferation of Esophageal Cancer Cells and Promotes Apoptosis by Inhibiting the Activity of the PI3K/AKT Pathway
Yingjian Song, Huimin Liu, Chunling Cui, Xiaonu Peng, Chaoyang Wang, Xudong Tian & Wenjun Li
Pages: 10883-10890
Published online: 30 Dec 2019
AbstractforSilencing of Peroxiredoxin 1 Inhibits the Proliferation of Esophageal Cancer Cells and Promotes Apoptosis by Inhibiting the Activity of the PI3K/AKT Pathway | Full Text | References | PDF (6 MB) | EPUB
  • 71 Views
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Article
RETRACTED ARTICLE: MiR-935 Promotes Clear Cell Renal Cell Carcinoma Migration and Invasion by Targeting IREB2
Fei Liu, Yuedong Chen, Bin Chen, Chunxiao Liu & Jinchun Xing
Pages: 10891-10900
Published online: 30 Dec 2019
AbstractforRETRACTED ARTICLE: MiR-935 Promotes Clear Cell Renal Cell Carcinoma Migration and Invasion by Targeting IREB2 | PDF (7.4 MB)
  • 11 Views
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Article
Radiotherapy for patients with completely resected pathologic IIIA(N2) non–small-cell lung cancer: a retrospective analysis
Ying Zhu, Lei Fu, Wang Jing, Li Kong & Jinming Yu
Pages: 10901-10908
Published online: 31 Dec 2019
AbstractforRadiotherapy for patients with completely resected pathologic IIIA(N2) non–small-cell lung cancer: a retrospective analysis | Full Text | References | PDF (531.2 KB) | EPUB
  • 83 Views
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Article
Survival After Abdominal Q-M Type B versus C2 Radical Hysterectomy for Early-Stage Cervical Cancer
Chunlin Chen, Wuliang Wang, Ping Liu, Pengfei Li, Lu Wang, Shuangling Jin, Xiaonong Bin & Jinghe Lang
Pages: 10909-10919
Published online: 31 Dec 2019
AbstractforSurvival After Abdominal Q-M Type B versus C2 Radical Hysterectomy for Early-Stage Cervical Cancer | Full Text | References | PDF (505.8 KB) | EPUB
  • 88 Views
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Article
New Preoperative Nomogram Using the Centrality Index to Predict High Nuclear Grade Clear Cell Renal Carcinoma
Zhan Feng, Shuangshuang Lou, Lixia Zhang, Liang Zhang, Wenting Lan, Minhong Wang, Qijun Shen, Zhengyu Hu & Feng Chen
Pages: 10921-10928
Published online: 03 Jan 2020
AbstractforNew Preoperative Nomogram Using the Centrality Index to Predict High Nuclear Grade Clear Cell Renal Carcinoma | Full Text | References | PDF (1.6 MB) | EPUB
  • 90 Views
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Article
Pre/Post-Treatment Dynamic of Inflammatory Markers Has Prognostic Value in Patients with Small Hepatocellular Carcinoma Managed by Stereotactic Body Radiation Therapy
Yuan Zhuang, Bao-Ying Yuan, Yong Hu, Gen-Wen Chen, Li Zhang, Xiao-Mei Zhao, Yi-Xing Chen & Zhao-Chong Zeng
Pages: 10929-10937
Published online: 03 Jan 2020
AbstractforPre/Post-Treatment Dynamic of Inflammatory Markers Has Prognostic Value in Patients with Small Hepatocellular Carcinoma Managed by Stereotactic Body Radiation Therapy | Full Text | References | PDF (1.6 MB) | EPUB
  • 66 Views
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Article
Circulating Tumor Cell Detection In Epithelial Ovarian Cancer Using Dual-Component Antibodies Targeting EpCAM And FRα
Na Li, Hao Zuo, Luojun Chen, Huali Liu, Jin Zhou, Yi Yao, Bin Xu, Hongyun Gong, Yiming Weng, Qinyong Hu, Qibin Song, Min Peng & Yanxiang Cheng
Pages: 10939-10948
Published online: 03 Jan 2020
AbstractforCirculating Tumor Cell Detection In Epithelial Ovarian Cancer Using Dual-Component Antibodies Targeting EpCAM And FRα | Full Text | References | PDF (4.7 MB) | EPUB
  • 107 Views
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Article
Time-Varying Effects of Marital Status on Gastric Cancer: A Population-Based Study
Bofei Li & Xuechen Hu
Pages: 10949-10955
Published online: 03 Jan 2020
AbstractforTime-Varying Effects of Marital Status on Gastric Cancer: A Population-Based Study | Full Text | References | PDF (1.2 MB) | EPUB
  • 89 Views
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Article
circPCNX and Pecanex Promote Hepatocellular Carcinoma Cell Viability by Inhibiting miR-506
Peng Sun, Xinyi Fan, Xiao Hu, Xiaoyue Fu, Qian Wei & Yunjin Zang
Pages: 10957-10967
Published online: 03 Jan 2020
AbstractforcircPCNX and Pecanex Promote Hepatocellular Carcinoma Cell Viability by Inhibiting miR-506 | Full Text | References | PDF (6.6 MB) | EPUB
  • 52 Views
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Article
Deficient Regulatory Innate Lymphoid Cells and Differential Expression of miRNAs in Acute Myeloid Leukemia Quantified by Next Generation Sequence
Jifeng Yu, Yingmei Li, Yue Pan, Yu Liu, Haizhou Xing, Xinsheng Xie, Dingming Wan & Zhongxing Jiang
Pages: 10969-10982
Published online: 03 Jan 2020
AbstractforDeficient Regulatory Innate Lymphoid Cells and Differential Expression of miRNAs in Acute Myeloid Leukemia Quantified by Next Generation Sequence | Full Text | References | PDF (3.7 MB) | EPUB
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