Clinical Pharmacology: Advances and Applications, Volume 13, Issue (2021)

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Clinical Pharmacology: Advances and Applications, Volume 13, Issue (2021)

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Original Research

Article
The Impact of First-Line Anti-Tubercular Drugs’ Pharmacokinetics on Treatment Outcome: A Systematic Review
Tesemma Sileshi, Esayas Tadesse, Eyasu Makonnen & Eleni Aklillu
Pages: 1-12
Published online: 12 Jan 2021
AbstractforThe Impact of First-Line Anti-Tubercular Drugs’ Pharmacokinetics on Treatment Outcome: A Systematic Review | Full Text | References | PDF (449.6 KB) | EPUB
  • 355 Views
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Open Access
Article
Penetration of Flurbiprofen from a Locally Applied Sore Throat Lozenge and Spray into Cadaveric Human Pharynx Tissue: A Novel ex vivo Model and Microautoradiography Method
Rob Turner, Sean Robert Wevrett, Suzanne Edmunds, Marc Brown, Anuradha Kulasekaran, Oluwajoba Adegoke & John Farrah
Pages: 13-20
Published online: 19 Jan 2021
AbstractforPenetration of Flurbiprofen from a Locally Applied Sore Throat Lozenge and Spray into Cadaveric Human Pharynx Tissue: A Novel ex vivo Model and Microautoradiography Method | Full Text | References | PDF (2.4 MB) | EPUB
  • 149 Views
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Open Access
Article
Pharmacokinetics and Toxicities of Oral Docetaxel Formulations Co-Administered with Ritonavir in Phase I Trials
Marit Vermunt, Serena Marchetti & Jos Beijnen
Pages: 21-32
Published online: 27 Jan 2021
AbstractforPharmacokinetics and Toxicities of Oral Docetaxel Formulations Co-Administered with Ritonavir in Phase I Trials | Full Text | References | PDF (2.4 MB) | EPUB
  • 124 Views
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Open Access

Case Report

Case Report
Successful Control of Hypoglycemia with Pasireotide LAR in a Patient with Inappropriate Insulin Secretion
Alexia Rouland, Benjamin Bouillet, Pauline Legris, Isabelle Simoneau, Jean-Michel Petit & Bruno Vergès
Pages: 33-37
Published online: 13 Nov 2022
AbstractforSuccessful Control of Hypoglycemia with Pasireotide LAR in a Patient with Inappropriate Insulin Secretion | Full Text | References | PDF (1.1 MB) | EPUB
  • 120 Views
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Open Access

Retraction

Retraction
Administration of Supplemental L-Tyrosine with Phenelzine: a Clinical Literature Review [Retraction]
Page: 39
Published online: 03 Mar 2021
CitationforAdministration of Supplemental L-Tyrosine with Phenelzine: a Clinical Literature Review [Retraction] | Full Text | PDF (161.1 KB) | EPUB
  • 72 Views
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Open Access
Retraction
The Parkinson’s Disease Death Rate: Carbidopa and Vitamin B6 [Retraction]
Page: 41
Published online: 13 Nov 2022
CitationforThe Parkinson’s Disease Death Rate: Carbidopa and Vitamin B6 [Retraction] | Full Text | PDF (161.2 KB) | EPUB
  • 76 Views
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Open Access
Retraction
Parkinson’s Disease: Carbidopa, Nausea, and Dyskinesia [Retraction]
Page: 43
Published online: 13 Nov 2022
CitationforParkinson’s Disease: Carbidopa, Nausea, and Dyskinesia [Retraction] | Full Text | PDF (161.4 KB) | EPUB
  • 81 Views
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Open Access

Original Research

Article
Efficacy of Generic Atorvastatin in a Real-World Setting
Panisa Manasirisuk, Nanthaphan Chainirun, Somsak Tiamkao, Sunee Lertsinudom, Kutcharin Phunikhom, Bundit Sawunyavisuth & Kittisak Sawanyawisuth
Pages: 45-51
Published online: 05 Mar 2021
AbstractforEfficacy of Generic Atorvastatin in a Real-World Setting | Full Text | References | PDF (263.9 KB) | EPUB
  • 382 Views
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Open Access

Review

Review Article
Clinical Impact of Liraglutide as a Treatment of Obesity
Heshma Alruwaili, Babak Dehestani & Carel W le Roux
Pages: 53-60
Published online: 11 Mar 2021
AbstractforClinical Impact of Liraglutide as a Treatment of Obesity | Full Text | References | PDF (291.4 KB) | EPUB
  • 1292 Views
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Open Access

Original Research

Article
Population Pharmacokinetics of CC-122
Yiming Cheng, Jian Chen, Michael Pourdehnad, Simon Zhou & Yan Li
Pages: 61-71
Published online: 13 Nov 2022
AbstractforPopulation Pharmacokinetics of CC-122 | Full Text | References | PDF (4.1 MB) | EPUB
  • 172 Views
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Open Access
Article
An Investigator-Initiated, Prospective, Single-Center, Open-Label Clinical Study to Evaluate Safety and Performance of Intra-Articular Hyaluronic Acid (IA-HA) (Biovisc Ortho) in Patients with Osteoarthritis (OA) of the Knee
Ajay Gupta, Chethan Channaveera, Vijender Anand & Satyaranjan Sethi
Pages: 73-82
Published online: 11 May 2021
AbstractforAn Investigator-Initiated, Prospective, Single-Center, Open-Label Clinical Study to Evaluate Safety and Performance of Intra-Articular Hyaluronic Acid (IA-HA) (Biovisc Ortho) in Patients with Osteoarthritis (OA) of the Knee | Full Text | References | PDF (1.3 MB) | EPUB
  • 165 Views
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Open Access
Article
Metformin as a Potential Adjuvant Antimicrobial Agent Against Multidrug Resistant Bacteria
Majed M Masadeh, Karem H Alzoubi, Majd M Masadeh & Zainah O Aburashed
Pages: 83-90
Published online: 11 May 2021
AbstractforMetformin as a Potential Adjuvant Antimicrobial Agent Against Multidrug Resistant Bacteria | Full Text | References | PDF (444.6 KB) | EPUB
  • 854 Views
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Open Access
Article
A Multicenter, Randomized, Double-Blind, Placebo-Controlled Trial Assessing Efficacy and Safety of a Novel Low-Dose Turmeric Extract Formulation in Healthy Adults with Chronic Knee Pain
Shefali Thanawala, Rajat Shah, Venkateswarlu Somepalli, KrishnaRaju Venkata Alluri, Prabakaran Desomayanandam & Arun Bhuvanendran
Pages: 91-100
Published online: 21 May 2021
AbstractforA Multicenter, Randomized, Double-Blind, Placebo-Controlled Trial Assessing Efficacy and Safety of a Novel Low-Dose Turmeric Extract Formulation in Healthy Adults with Chronic Knee Pain | Full Text | References | PDF (1.3 MB) | EPUB
  • 452 Views
  • 3 CrossRef citations
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Open Access
Article
Determination of Caffeine and Hydrogen Peroxide Antioxidant Activity of Raw and Roasted Coffee Beans Around Habru Woreda, Ethiopia Using UV-Vis Spectroscopy
Beshir Legas Muhammed, Mohammed Hussen Seid & Adere Tarekegne Habte
Pages: 101-113
Published online: 24 May 2021
AbstractforDetermination of Caffeine and Hydrogen Peroxide Antioxidant Activity of Raw and Roasted Coffee Beans Around Habru Woreda, Ethiopia Using UV-Vis Spectroscopy | Full Text | References | PDF (1.3 MB) | EPUB
  • 668 Views
  • 1 CrossRef citations
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Open Access
Article
Rupatadine Oral Solution Titration by Body Weight in Paediatric Patients Suffering from Allergic Rhinitis: A Population Pharmacokinetic Study
Eva Santamaria, Iñaki Izquierdo & Marta Valle
Pages: 115-122
Published online: 08 Jun 2021
AbstractforRupatadine Oral Solution Titration by Body Weight in Paediatric Patients Suffering from Allergic Rhinitis: A Population Pharmacokinetic Study | Full Text | References | PDF (888.7 KB) | EPUB
  • 147 Views
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Open Access
Article
Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of the MK2 Inhibitor ATI-450 in Healthy Subjects: A Placebo-Controlled, Randomized Phase 1 Study
David Gordon, Edward T Hellriegel, Heidi Rath Hope, David Burt & Joseph B Monahan
Pages: 123-134
Published online: 10 Jun 2021
AbstractforSafety, Tolerability, Pharmacokinetics, and Pharmacodynamics of the MK2 Inhibitor ATI-450 in Healthy Subjects: A Placebo-Controlled, Randomized Phase 1 Study | Full Text | References | PDF (478.3 KB) | EPUB
  • 292 Views
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Open Access

Review

Review Article
Guselkumab for the Treatment of Palmoplantar Pustulosis: A Japanese Perspective
Toshiyuki Yamamoto
Pages: 135-143
Published online: 23 Jun 2021
AbstractforGuselkumab for the Treatment of Palmoplantar Pustulosis: A Japanese Perspective | Full Text | References | PDF (3.6 MB) | EPUB
  • 178 Views
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Open Access

Clinical Trial Report

Case Report
Evaluation of the Pharmacokinetics of Trazpiroben (TAK-906), a Peripherally Selective D2/D3 Dopamine Receptor Antagonist, in the Presence and Absence of Itraconazole, a Potent CYP 3A4 Inhibitor
Chunlin Chen, Wenwen Zhang, Muhammad Bari, Cristina Almansa, Mike Baratta & Maria Rosario
Pages: 145-155
Published online: 12 Jul 2021
AbstractforEvaluation of the Pharmacokinetics of Trazpiroben (TAK-906), a Peripherally Selective D2/D3 Dopamine Receptor Antagonist, in the Presence and Absence of Itraconazole, a Potent CYP 3A4 Inhibitor | Full Text | References | PDF (419.1 KB) | EPUB
  • 102 Views
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Open Access

Original Research

Article
Evaluation of Antimalarial Activity of 80% Methanolic Root Extract of Dorstenia barnimiana Against Plasmodium berghei–Infected Mice
Dagninet Derebe, Muluken Wubetu & Amare Alamirew
Pages: 157-167
Published online: 16 Jul 2021
AbstractforEvaluation of Antimalarial Activity of 80% Methanolic Root Extract of Dorstenia barnimiana Against Plasmodium berghei–Infected Mice | Full Text | References | PDF (460.2 KB) | EPUB
  • 135 Views
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Open Access

Review

Review Article
Novel Approaches to Treating Relapsed and Refractory Multiple Myeloma with a Focus on Recent Approvals of Belantamab Mafodotin and Selinexor
Nisha S Joseph, Yu-Tzu Tai, Kenneth C Anderson & Sagar Lonial
Pages: 169-180
Published online: 18 Aug 2021
AbstractforNovel Approaches to Treating Relapsed and Refractory Multiple Myeloma with a Focus on Recent Approvals of Belantamab Mafodotin and Selinexor | Full Text | References | PDF (358.7 KB) | EPUB
  • 145 Views
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Open Access

Case Report

Case Report
Anti-Xa Inhibitor-Induced Hemorrhagic Pruritic Rash: A Case Report on Possible Cross-Reactivity Between Apixaban and Rivaroxaban
Takla R Anis & Whitney Jandreau
Pages: 181-184
Published online: 13 Nov 2022
AbstractforAnti-Xa Inhibitor-Induced Hemorrhagic Pruritic Rash: A Case Report on Possible Cross-Reactivity Between Apixaban and Rivaroxaban | Full Text | References | PDF (225.2 KB) | EPUB
  • 173 Views
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Open Access

Original Research

Article
Antiviral Combination Clinically Better Than Standard Therapy in Severe but Not in Non-Severe COVID-19
Prasan Kumar Panda, Budha O Singh, Bikram Moirangthem, Yogesh Arvind Bahurupi, Sarama Saha, Girraj Saini, Minakshi Dhar, Mukesh Bairwa, Venkatesh Srinivasa Pai, Ankit Agarwal, Girish Sindhwani, Shailendra Handu & Ravi Kant
Pages: 185-195
Published online: 13 Nov 2022
AbstractforAntiviral Combination Clinically Better Than Standard Therapy in Severe but Not in Non-Severe COVID-19 | Full Text | References | PDF (3.2 MB) | EPUB
  • 141 Views
  • 3 CrossRef citations
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Open Access
Article
Comparing the Efficacy of a Nurse-Driven and a Physician-Driven Diabetic Ketoacidosis (DKA) Treatment Protocol
Takla R Anis, Marybeth Boudreau & Tyson Thornton
Pages: 197-202
Published online: 13 Nov 2022
AbstractforComparing the Efficacy of a Nurse-Driven and a Physician-Driven Diabetic Ketoacidosis (DKA) Treatment Protocol | Full Text | References | PDF (239.1 KB) | EPUB
  • 555 Views
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Open Access

Case Report

Case Report
A Case of Thrombocytosis Associated with Enoxaparin Therapy in an Adolescent
Robert Murray & Joseph T Tobias
Pages: 203-207
Published online: 18 Oct 2021
AbstractforA Case of Thrombocytosis Associated with Enoxaparin Therapy in an Adolescent | Full Text | References | PDF (2.3 MB) | EPUB
  • 154 Views
  • 1 CrossRef citations
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Open Access

Review

Review Article
Pharmacological Management of Urinary Incontinence: Current and Emerging Treatment
Carlo Gandi & Emilio Sacco
Pages: 209-223
Published online: 13 Nov 2022
AbstractforPharmacological Management of Urinary Incontinence: Current and Emerging Treatment | Full Text | References | PDF (1.4 MB) | EPUB
  • 448 Views
  • 2 CrossRef citations
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Open Access
Review Article
Potential of Quinine Sulfate for COVID-19 Treatment and Its Safety Profile: Review
Irma Rahayu Latarissa, Melisa Intan Barliana, Anna Meiliana & Keri Lestari
Pages: 225-234
Published online: 13 Nov 2022
AbstractforPotential of Quinine Sulfate for COVID-19 Treatment and Its Safety Profile: Review | Full Text | References | PDF (1.6 MB) | EPUB
  • 534 Views
  • 1 CrossRef citations
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Open Access
Review Article
Pharmacological Profile of Viltolarsen for the Treatment of Duchenne Muscular Dystrophy: A Japanese Experience
Rohini Roy Roshmi & Toshifumi Yokota
Pages: 235-242
Published online: 13 Nov 2022
AbstractforPharmacological Profile of Viltolarsen for the Treatment of Duchenne Muscular Dystrophy: A Japanese Experience | Full Text | References | PDF (1.3 MB) | EPUB
  • 348 Views
  • 2 CrossRef citations
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Open Access

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