Journal of Experimental Pharmacology, Volume 4, Issue (2012)

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Journal of Experimental Pharmacology, Volume 4, Issue (2012)

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Original Research

Article
Restoration of renal hemodynamics and functions during black cumin (Nigella sativa) administration in streptozotocin-induced diabetic rats
Mariem Yusuksawad & Narongsak Chaiyabutr
Pages: 1-7
Published online: 23 Dec 2011
AbstractforRestoration of renal hemodynamics and functions during black cumin (Nigella sativa) administration in streptozotocin-induced diabetic rats | Full Text | References | PDF (202.8 KB)
  • 149 Views
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Open Access

Review

Review Article
Flavonoids as GABAA receptor ligands: the whole story?
Cristina Wasowski & Mariel Marder
Pages: 9-24
Published online: 18 Dec 2022
AbstractforFlavonoids as GABAA receptor ligands: the whole story? | Full Text | References | PDF (1.2 MB)
  • 316 Views
  • 15 CrossRef citations
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Open Access
Review Article
Hibiscus sabdariffa L., roselle calyx, from ethnobotany to pharmacology
Octavio Carvajal-Zarrabal, Dulce María Barradas-Dermitz, Zaida Orta-Flores, Patricia Margaret Hayward-Jones, Cirilo Nolasco-Hipólito, M Guadalupe Aguilar-Uscanga, Anilú Miranda-Medina & Kopli Bin Bujang
Pages: 25-39
Published online: 18 Dec 2022
AbstractforHibiscus sabdariffa L., roselle calyx, from ethnobotany to pharmacology | Full Text | References | PDF (337.6 KB)
  • 453 Views
  • 27 CrossRef citations
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Open Access

Original Research

Article
Antiarthritic effect of aqueous and ethanolic leaf extracts of Pistia stratiotes in adjuvant-induced arthritis in Sprague-Dawley rats
Samuel Kyei, George A Koffuor & Johnson N Boampong
Pages: 41-51
Published online: 18 Dec 2022
AbstractforAntiarthritic effect of aqueous and ethanolic leaf extracts of Pistia stratiotes in adjuvant-induced arthritis in Sprague-Dawley rats | Full Text | References | PDF (4.6 MB)
  • 224 Views
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Open Access
Article
A quantitative way to estimate clinical off-target effects for human membrane brain targets in CNS research and development
Athan Spiros & Hugo Geerts
Pages: 53-61
Published online: 18 Dec 2022
AbstractforA quantitative way to estimate clinical off-target effects for human membrane brain targets in CNS research and development | Full Text | References | PDF (266 KB)
  • 64 Views
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Open Access
Article
The efficacy of stingless bee honey for the treatment of bacteria-induced conjunctivitis in guinea pigs
Alex Azuka Ilechie, Peter Kofi Kwapong, Edwin Mate-Kole, Samuel Kyei & Charles Darko-Takyi
Pages: 63-68
Published online: 18 May 2012
AbstractforThe efficacy of stingless bee honey for the treatment of bacteria-induced conjunctivitis in guinea pigs | Full Text | References | PDF (156.4 KB)
  • 157 Views
  • 13 CrossRef citations
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Open Access
Article
Oseltamivir reduces hippocampal abnormal EEG activities after a virus infection (influenza) in isoflurane-anesthetized rats
Youssouf Cissé, Isao Inoue & Hiroshi Kido
Pages: 69-76
Published online: 18 Dec 2022
AbstractforOseltamivir reduces hippocampal abnormal EEG activities after a virus infection (influenza) in isoflurane-anesthetized rats | Full Text | References | PDF (494.1 KB)
  • 56 Views
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Open Access

Review

Review Article
The extracellular signal-regulated kinase (ERK) pathway: a potential therapeutic target in hypertension
Richard E Roberts
Pages: 77-83
Published online: 02 Aug 2012
AbstractforThe extracellular signal-regulated kinase (ERK) pathway: a potential therapeutic target in hypertension | Full Text | References | PDF (237.8 KB)
  • 85 Views
  • 20 CrossRef citations
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Open Access
Review Article
Investigational agents in the treatment of Parkinson’s disease: focus on safinamide
Naveed M Malek & Donald G Grosset
Pages: 85-90
Published online: 15 Aug 2012
AbstractforInvestigational agents in the treatment of Parkinson’s disease: focus on safinamide | Full Text | References | PDF (150.1 KB)
  • 104 Views
  • 8 CrossRef citations
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Open Access
Review Article
Reduction in cancer risk by selective and nonselective cyclooxygenase-2 (COX-2) inhibitors
Randall E Harris, Joanne Beebe & Galal A Alshafie
Pages: 91-96
Published online: 13 Aug 2012
AbstractforReduction in cancer risk by selective and nonselective cyclooxygenase-2 (COX-2) inhibitors | Full Text | References | PDF (178.3 KB)
  • 96 Views
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Open Access
Review Article
Investigational agents in metastatic basal cell carcinoma: focus on vismodegib
Nicolas Batty, Ellen Kossoff & Grace K Dy
Pages: 97-103
Published online: 18 Dec 2022
AbstractforInvestigational agents in metastatic basal cell carcinoma: focus on vismodegib | Full Text | References | PDF (329.7 KB)
  • 67 Views
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Open Access

Original Research

Article
Action of AferBio (fermented food) in a rat inflammatory model
Anna Eliza Maciel de Faria Mota Oliveira, Benedito Junior Lima de Medeiros, Hugo Alexandre Favacho & José Carlos Tavares Carvalho
Pages: 105-111
Published online: 18 Dec 2022
AbstractforAction of AferBio (fermented food) in a rat inflammatory model | Full Text | References | PDF (695.6 KB)
  • 50 Views
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Open Access

Review

Review Article
The pharmacology and therapeutic potential of (−)-huperzine A
Maung Kyaw Moe Tun & Seth B Herzon
Pages: 113-123
Published online: 18 Dec 2022
AbstractforThe pharmacology and therapeutic potential of (−)-huperzine A | Full Text | References | PDF (434.8 KB)
  • 125 Views
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Open Access

Original Research

Article
Ouabain inhibits monocyte activation in vitro: prevention of the proinflammatory mCD14+/CD16+ subset appearance and cell-size progression
Raphael C Valente, Elizabeth G Araujo & Vivian M Rumjanek
Pages: 125-140
Published online: 18 Dec 2022
AbstractforOuabain inhibits monocyte activation in vitro: prevention of the proinflammatory mCD14+/CD16+ subset appearance and cell-size progression | Full Text | References | PDF (1.9 MB)
  • 58 Views
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Open Access

Review

Review Article
The therapeutic potential of RORγ modulators in the treatment of human disease
Mi Ra Chang, Devrishi Goswami, Becky A Mercer & Patrick R Griffin
Pages: 141-148
Published online: 18 Dec 2022
AbstractforThe therapeutic potential of RORγ modulators in the treatment of human disease | Full Text | References | PDF (325.3 KB)
  • 74 Views
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Open Access

Original Research

Article
Efficacy of ipamorelin, a ghrelin mimetic, on gastric dysmotility in a rodent model of postoperative ileus
Beverley Greenwood-Van Meerveld, Karl Tyler, Ehsan Mohammadi & Claudio Pietra
Pages: 149-155
Published online: 18 Dec 2022
AbstractforEfficacy of ipamorelin, a ghrelin mimetic, on gastric dysmotility in a rodent model of postoperative ileus | Full Text | References | PDF (224.4 KB)
  • 109 Views
  • 4 CrossRef citations
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Open Access
Article
The anticancer activity of dichloromethane crude extract obtained from Calea pinnatifida
Gabriela M Marchetti, Karina A Silva, Arianny N Santos, Ilza MO Sousa, Sirlene V Tinti, Glyn M Figueira, Mary A Foglio & João E Carvalho
Pages: 157-162
Published online: 18 Dec 2022
AbstractforThe anticancer activity of dichloromethane crude extract obtained from Calea pinnatifida | Full Text | References | PDF (186.7 KB)
  • 119 Views
  • 4 CrossRef citations
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Open Access

Review

Review Article
Effectiveness of nootropic drugs with cholinergic activity in treatment of cognitive deficit: a review
Luisa Colucci, Massimiliano Bosco, Antonio Rosario Ziello, Raffaele Rea, Francesco Amenta & Angiola Maria Fasanaro
Pages: 163-172
Published online: 18 Dec 2022
AbstractforEffectiveness of nootropic drugs with cholinergic activity in treatment of cognitive deficit: a review | Full Text | References | PDF (224.1 KB)
  • 805 Views
  • 35 CrossRef citations
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Open Access
Review Article
Hedgehog signaling pathway and its targets for treatment in basal cell carcinoma
Danilo Cucchi, Maria Anna Occhione, Alberto Gulino & Enrico De Smaele
Pages: 173-185
Published online: 18 Dec 2022
AbstractforHedgehog signaling pathway and its targets for treatment in basal cell carcinoma | Full Text | References | PDF (678.5 KB)
  • 87 Views
  • 1 CrossRef citations
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Open Access

Original Research

Article
Morphine treatment alters nucleotidase activities in rat blood serum
Joanna Ripoll Rozisky, Yasmine Nonose, Gabriela Laste, Vinicius Souza dos Santos, Isabel Cristina de Macedo, Ana Maria Oliveira Battastini, Wolnei Caumo & Iraci LS Torres
Pages: 187-193
Published online: 18 Dec 2022
AbstractforMorphine treatment alters nucleotidase activities in rat blood serum | Full Text | References | PDF (284.4 KB)
  • 53 Views
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