Journal of Experimental Pharmacology, Volume 13, Issue (2021)

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Journal of Experimental Pharmacology, Volume 13, Issue (2021)

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Review

Review Article
Experimental Pharmacotherapy for COVID-19: The Latest Advances
Pasquale Pagliano, Giuliana Scarpati, Carmine Sellitto, Valeria Conti, Anna Maria Spera, Tiziana Ascione, Ornella Piazza & Amelia Filippelli
Pages: 1-13
Published online: 30 Nov 2022
AbstractforExperimental Pharmacotherapy for COVID-19: The Latest Advances | Full Text | References | PDF (1.6 MB) | EPUB
  • 195 Views
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Original Research

Article
In vitro Antileishmanial Activity of Some Ethiopian Medicinal Plants
Hulubanchi Nigatu, Alemnesh Belay, Hiwot Ayalew, Besufekad Abebe, Alemu Tadesse, Yitagesu Tewabe & Abel Degu
Pages: 15-22
Published online: 30 Nov 2022
AbstractforIn vitro Antileishmanial Activity of Some Ethiopian Medicinal Plants | Full Text | References | PDF (334.7 KB) | EPUB
  • 421 Views
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Review

Review Article
Montelukast: The New Therapeutic Option for the Treatment of Epilepsy
Bekalu Amare Tesfaye, Haftom Gebregergs Hailu, Kaleab Alemayehu Zewdie, Muluken Altaye Ayza & Derbew Fikadu Berhe
Pages: 23-31
Published online: 30 Nov 2022
AbstractforMontelukast: The New Therapeutic Option for the Treatment of Epilepsy | Full Text | References | PDF (970.6 KB) | EPUB
  • 284 Views
  • 3 CrossRef citations
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Open Access
Review Article
Binge Eating Disorder: A 5-Year Retrospective Study on Experimental Drugs
Michelle N Levitan, Marcelo Papelbaum, Mauro G Carta, Jose C Appolinario & Antonio E Nardi
Pages: 33-47
Published online: 30 Nov 2022
AbstractforBinge Eating Disorder: A 5-Year Retrospective Study on Experimental Drugs | Full Text | References | PDF (380.1 KB) | EPUB
  • 540 Views
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Open Access
Review Article
Experimental Serotonergic Agents for the Treatment of Schizophrenia
Enrico Capuzzi, Alice Caldiroli, Veronica Ciscato, Stefania Russo & Massimiliano Buoli
Pages: 49-67
Published online: 30 Nov 2022
AbstractforExperimental Serotonergic Agents for the Treatment of Schizophrenia | Full Text | References | PDF (1.5 MB) | EPUB
  • 297 Views
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Open Access

Original Research

Article
Antimalarial Activity of Methanolic Extracts and Solvent Fractions of Combretum molle Leaves in Plasmodium berghei Infected Mice
Melkamu Adigo Shibeshi, Engdaw Fentahun Enyew, Getnet Mequanint Adinew & Tezera Jemere Aragaw
Pages: 69-89
Published online: 30 Nov 2022
AbstractforAntimalarial Activity of Methanolic Extracts and Solvent Fractions of Combretum molle Leaves in Plasmodium berghei Infected Mice | Full Text | References | PDF (5.1 MB) | EPUB
  • 191 Views
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Review

Review Article
Novel Experimental Agents for the Treatment of Hypercholesterolemia
Ivan Pećin & Željko Reiner
Pages: 91-100
Published online: 30 Nov 2022
AbstractforNovel Experimental Agents for the Treatment of Hypercholesterolemia | Full Text | References | PDF (336.5 KB) | EPUB
  • 395 Views
  • 12 CrossRef citations
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Open Access
Review Article
Experimental Therapeutics for the Treatment of Osteoarthritis
Gundula Schulze-Tanzil
Pages: 101-125
Published online: 30 Nov 2022
AbstractforExperimental Therapeutics for the Treatment of Osteoarthritis | Full Text | References | PDF (4.3 MB) | EPUB
  • 464 Views
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Open Access
Review Article
Experimental Therapeutic Solutions for Behcet’s Disease
Burçin Cansu Bozca & Erkan Alpsoy
Pages: 127-145
Published online: 30 Nov 2022
AbstractforExperimental Therapeutic Solutions for Behcet’s Disease | Full Text | References | PDF (671.8 KB) | EPUB
  • 235 Views
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Open Access

Original Research

Article
Cardioprotective Effect of Crude Extract and Solvent Fractions of Urtica simensis Leaves on Cyclophosphamide-Induced Myocardial Injury in Rats
Bekalu Amare Tesfaye, Abera Hadgu Berhe, Dawit Zewdu Wondafrash & Derbew Fikadu Berhe
Pages: 147-160
Published online: 30 Nov 2022
AbstractforCardioprotective Effect of Crude Extract and Solvent Fractions of Urtica simensis Leaves on Cyclophosphamide-Induced Myocardial Injury in Rats | Full Text | References | PDF (1.2 MB) | EPUB
  • 368 Views
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Review

Review Article
Experimental Agents for the Treatment of Atherosclerosis: New Directions
Errika Voutyritsa, Georgios Kyriakos, Alexandros Patsouras, Christos Damaskos, Anna Garmpi, Evangelos Diamantis, Nikolaos Garmpis & Spyridon Savvanis
Pages: 161-179
Published online: 30 Nov 2022
AbstractforExperimental Agents for the Treatment of Atherosclerosis: New Directions | Full Text | References | PDF (365.6 KB) | EPUB
  • 306 Views
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Open Access
Review Article
Experimental Therapeutics in Treatment-Resistant Major Depressive Disorder
Mandeep Kaur & Marsal Sanches
Pages: 181-196
Published online: 30 Nov 2022
AbstractforExperimental Therapeutics in Treatment-Resistant Major Depressive Disorder | Full Text | References | PDF (388 KB) | EPUB
  • 328 Views
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Open Access
Review Article
Investigational Rho Kinase Inhibitors for the Treatment of Glaucoma
Ghadeer Al-Humimat, Ibtisam Marashdeh, Duaa Daradkeh & Karanjit Kooner
Pages: 197-212
Published online: 30 Nov 2022
AbstractforInvestigational Rho Kinase Inhibitors for the Treatment of Glaucoma | Full Text | References | PDF (4.9 MB) | EPUB
  • 366 Views
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Open Access

Original Research

Article
Evaluation of the Diuretic Activity of Aqueous and 80% Methanol Extracts of Croton macrostachyus(Euphorbiaceae) Leaves in Saline-Loaded Rats
Sara Tufer, Ephrem Engidawork, Akeberegn Gorems Ayele & Chala Bashea
Pages: 213-221
Published online: 30 Nov 2022
AbstractforEvaluation of the Diuretic Activity of Aqueous and 80% Methanol Extracts of Croton macrostachyus(Euphorbiaceae) Leaves in Saline-Loaded Rats | Full Text | References | PDF (457.1 KB) | EPUB
  • 294 Views
  • 1 CrossRef citations
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Open Access
Article
Assessment of Reproductive Toxicity of Hydroethanolic Root Extracts of Caesalpinia benthamiana, Sphenocentrum jollyanum, and Paullinia pinnata
Mavis Baffoe, George Koffuor, Agyapong Baffour-Awuah & Lorraine Sallah
Pages: 223-234
Published online: 30 Nov 2022
AbstractforAssessment of Reproductive Toxicity of Hydroethanolic Root Extracts of Caesalpinia benthamiana, Sphenocentrum jollyanum, and Paullinia pinnata | Full Text | References | PDF (9.4 MB) | EPUB
  • 357 Views
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Review

Review Article
Experimental GABA A Receptor Agonists and Allosteric Modulators for the Treatment of Focal Epilepsy
Slobodan M Janković, Miralem Dješević & Snežana V Janković
Pages: 235-244
Published online: 30 Nov 2022
AbstractforExperimental GABA A Receptor Agonists and Allosteric Modulators for the Treatment of Focal Epilepsy | Full Text | References | PDF (335.3 KB) | EPUB
  • 462 Views
  • 11 CrossRef citations
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Review Article
Novel Experimental Drugs for Treatment of Multiple Myeloma
Massimo Offidani, Laura Corvatta, Sonia Morè & Attilio Olivieri
Pages: 245-264
Published online: 30 Nov 2022
AbstractforNovel Experimental Drugs for Treatment of Multiple Myeloma | Full Text | References | PDF (2.5 MB) | EPUB
  • 230 Views
  • 13 CrossRef citations
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Open Access
Review Article
Experimental Therapeutic Strategies in Epilepsies Using Anti-Seizure Medications
Fakher Rahim, Reza Azizimalamiri, Mehdi Sayyah & Alireza Malayeri
Pages: 265-290
Published online: 30 Nov 2022
AbstractforExperimental Therapeutic Strategies in Epilepsies Using Anti-Seizure Medications | Full Text | References | PDF (2.7 MB) | EPUB
  • 429 Views
  • 6 CrossRef citations
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Open Access
Review Article
New Avenues for Phosphodiesterase Inhibitors in Asthma
Maria Gabriella Matera, Josuel Ora, Francesco Cavalli, Paola Rogliani & Mario Cazzola
Pages: 291-302
Published online: 30 Nov 2022
AbstractforNew Avenues for Phosphodiesterase Inhibitors in Asthma | Full Text | References | PDF (356.4 KB) | EPUB
  • 217 Views
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Review Article
Advances in Our Understanding of the Molecular Mechanisms of Action of Cisplatin in Cancer Therapy
Paul B Tchounwou, Shaloam Dasari, Felicite K Noubissi, Paresh Ray & Sanjay Kumar
Pages: 303-328
Published online: 30 Nov 2022
AbstractforAdvances in Our Understanding of the Molecular Mechanisms of Action of Cisplatin in Cancer Therapy | Full Text | References | PDF (5.8 MB) | EPUB
  • 3319 Views
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Open Access
Review Article
Experimental and Investigational Targeted Therapies for the Management of Fibrosis in NASH: An Update
Tsipora M Huisman, Douglas T Dieterich & Scott L Friedman
Pages: 329-338
Published online: 30 Nov 2022
AbstractforExperimental and Investigational Targeted Therapies for the Management of Fibrosis in NASH: An Update | Full Text | References | PDF (918.5 KB) | EPUB
  • 264 Views
  • 10 CrossRef citations
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Open Access
Review Article
The Pathological Role of Pro(Renin) Receptor in Renal Inflammation
Syed S Quadri, Caleb Cooper, Dawood Ghaffar, Hitesh Vaishnav & Ludmila Nahar
Pages: 339-344
Published online: 30 Nov 2022
AbstractforThe Pathological Role of Pro(Renin) Receptor in Renal Inflammation | Full Text | References | PDF (933.6 KB) | EPUB
  • 128 Views
  • 5 CrossRef citations
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Open Access
Review Article
Experimental Pharmacotherapy for Dry Eye Disease: A Review
Monica Baiula & Santi Spampinato
Pages: 345-358
Published online: 30 Nov 2022
AbstractforExperimental Pharmacotherapy for Dry Eye Disease: A Review | Full Text | References | PDF (379.2 KB) | EPUB
  • 383 Views
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Review Article
Experimental Disease-Modifying Agents for Frontotemporal Lobar Degeneration
Marcello Giunta, Eino Solje, Fabrizio Gardoni, Barbara Borroni & Alberto Benussi
Pages: 359-376
Published online: 30 Nov 2022
AbstractforExperimental Disease-Modifying Agents for Frontotemporal Lobar Degeneration | Full Text | References | PDF (555 KB) | EPUB
  • 198 Views
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Open Access
Review Article
New Pharmacologic Approaches to Bronchopulmonary Dysplasia
Katelyn Roberts, Gretchen Stepanovich, Varsha Bhatt-Mehta & Steven M Donn
Pages: 377-396
Published online: 30 Nov 2022
AbstractforNew Pharmacologic Approaches to Bronchopulmonary Dysplasia | Full Text | References | PDF (3.5 MB) | EPUB
  • 234 Views
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Open Access
Review Article
Experimental Dopamine Reuptake Inhibitors in Parkinson’s Disease: A Review of the Evidence
Thomas Müller
Pages: 397-408
Published online: 30 Nov 2022
AbstractforExperimental Dopamine Reuptake Inhibitors in Parkinson’s Disease: A Review of the Evidence | Full Text | References | PDF (1.4 MB) | EPUB
  • 429 Views
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Open Access
Review Article
Review on Experimental Treatment Strategies Against Trypanosoma cruzi
Ana Lia Mazzeti, Patricia Capelari-Oliveira, Maria Terezinha Bahia & Vanessa Carla Furtado Mosqueira
Pages: 409-432
Published online: 30 Nov 2022
AbstractforReview on Experimental Treatment Strategies Against Trypanosoma cruzi | Full Text | References | PDF (5 MB) | EPUB
  • 956 Views
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Open Access
Review Article
Emerging and Experimental Agents for Anal Cancer: What is New?
João Paulo F Farias, Maria Helena C Rangel da Silva & Alexandre A Jácome
Pages: 433-440
Published online: 09 Apr 2021
AbstractforEmerging and Experimental Agents for Anal Cancer: What is New? | Full Text | References | PDF (322 KB) | EPUB
  • 134 Views
  • 5 CrossRef citations
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Open Access
Review Article
Experimental Drugs for Panic Disorder: An Updated Systematic Review
Daniela Caldirola, Alessandra Alciati, Francesco Cuniberti & Giampaolo Perna
Pages: 441-459
Published online: 15 Apr 2021
AbstractforExperimental Drugs for Panic Disorder: An Updated Systematic Review | Full Text | References | PDF (541.6 KB) | EPUB
  • 393 Views
  • 5 CrossRef citations
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Open Access
Review Article
Experimental Drugs for the Treatment of Hepatitis D
Lisa Sandmann & Markus Cornberg
Pages: 461-468
Published online: 16 Apr 2021
AbstractforExperimental Drugs for the Treatment of Hepatitis D | Full Text | References | PDF (325.2 KB) | EPUB
  • 166 Views
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Open Access
Review Article
Pathophysiological Mechanisms and Experimental Pharmacotherapy for L-Dopa-Induced Dyskinesia
Andrea Fabbrini & Andrea Guerra
Pages: 469-485
Published online: 29 Apr 2021
AbstractforPathophysiological Mechanisms and Experimental Pharmacotherapy for L-Dopa-Induced Dyskinesia | Full Text | References | PDF (501.9 KB) | EPUB
  • 312 Views
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Open Access
Review Article
Experimental Drugs with the Potential to Treat Atopic Eczema
Kam Lun Ellis Hon, Vivian P Y Chan & Alexander K C Leung
Pages: 487-498
Published online: 30 Nov 2022
AbstractforExperimental Drugs with the Potential to Treat Atopic Eczema | Full Text | References | PDF (349.3 KB) | EPUB
  • 301 Views
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Open Access

Original Research

Article
Antioxidant and Antimicrobial Activity of Solvent Fractions of Calpurnia aurea (Ait.) Benth. (Fabaceae)
Dessie Belay, Ambaye Kenubih, Mohammed Yesuf, Elias Kebede, Muluken Yayeh & Mastewal Birhan
Pages: 499-509
Published online: 30 Nov 2022
AbstractforAntioxidant and Antimicrobial Activity of Solvent Fractions of Calpurnia aurea (Ait.) Benth. (Fabaceae) | Full Text | References | PDF (453.9 KB) | EPUB
  • 512 Views
  • 3 CrossRef citations
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Open Access
Article
Phytochemical Screening and in-vitro Evaluation of Antibacterial Activities of Echinops amplexicaulis, Ruta chalepensis and Salix subserrata Against Selected Pathogenic Bacterial Strains in West Shewa Zone, Ethiopia
Lencho Megersa Marami, Getachew Mulatu Dilba, Dagmawit Atalel Babele, Edilu Jorga Sarba, Askale Gizaw, Wakuma Mitiku Bune, Morka Dandecha Bayu, Petros Admasu, Abraham Mekbeb, Miressa Tadesse, Kebede Abdisa & Dejene Bayisa
Pages: 511-520
Published online: 18 May 2021
AbstractforPhytochemical Screening and in-vitro Evaluation of Antibacterial Activities of Echinops amplexicaulis, Ruta chalepensis and Salix subserrata Against Selected Pathogenic Bacterial Strains in West Shewa Zone, Ethiopia | Full Text | References | PDF (308.1 KB) | EPUB
  • 318 Views
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Open Access
Article
Combinatorial Therapies to Overcome BRAF/MEK Inhibitors Resistance in Melanoma Cells: An in vitro Study
Helena Pópulo, Beatriz Domingues, Cristina Sampaio, José Manuel Lopes & Paula Soares
Pages: 521-535
Published online: 24 May 2021
AbstractforCombinatorial Therapies to Overcome BRAF/MEK Inhibitors Resistance in Melanoma Cells: An in vitro Study | Full Text | References | PDF (662.9 KB) | EPUB
  • 182 Views
  • 3 CrossRef citations
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Open Access
Article
Wound Healing Activity of 80% Methanol Leaf Extract of Zehneria scabra (L.f) Sond (Cucurbitaceae) in Mice
Bezu Tekleyes, Solomon Assefa Huluka, Kebede Wondu & Yohannes Tsegyie Wondmkun
Pages: 537-544
Published online: 31 May 2021
AbstractforWound Healing Activity of 80% Methanol Leaf Extract of Zehneria scabra (L.f) Sond (Cucurbitaceae) in Mice | Full Text | References | PDF (477.2 KB) | EPUB
  • 766 Views
  • 10 CrossRef citations
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Article
Pharmacokinetics and Safety of an Intravitreal Humanized Anti-VEGF-A Monoclonal Antibody (PRO-169), a Biosimilar Candidate to Bevacizumab
Patricia Muñoz-Villegas, Alejandra Sanchez-Rios, Mayra G Quinonez-Alvarado, Oscar Olvera-Montaño, Juan D Quintana-Hau & Leopoldo Baiza-Duran
Pages: 545-554
Published online: 30 Nov 2022
AbstractforPharmacokinetics and Safety of an Intravitreal Humanized Anti-VEGF-A Monoclonal Antibody (PRO-169), a Biosimilar Candidate to Bevacizumab | Full Text | References | PDF (350.7 KB) | EPUB
  • 197 Views
  • 1 CrossRef citations
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Open Access
Article
Developmental Toxicity of Ethanolic Extracts of Leaves of Achyranthes aspera, Amaranthaceae in Rat Embryos and Fetuses
Daniel Teshome, Chalachew Tiruneh, Leykun Berhanu, Gete Berihun & Zebader Walle Belete
Pages: 555-563
Published online: 02 Jun 2021
AbstractforDevelopmental Toxicity of Ethanolic Extracts of Leaves of Achyranthes aspera, Amaranthaceae in Rat Embryos and Fetuses | Full Text | References | PDF (281.5 KB) | EPUB
  • 356 Views
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Open Access

Review

Review Article
Does Chemically Modified Curcumin Control the Progression of Periodontitis? A Systematic Review
Esam Dhaifullah, Hassan S Seayed, Diana Mostafa, Abdul Majeed M Alharbi & Waleed M Alotaibi
Pages: 565-575
Published online: 09 Jun 2021
AbstractforDoes Chemically Modified Curcumin Control the Progression of Periodontitis? A Systematic Review | Full Text | References | PDF (1.6 MB) | EPUB
  • 145 Views
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Open Access
Review Article
Updates in the Treatment of Peripheral T-Cell Lymphomas
Khalil Saleh, Jean-Marie Michot & Vincent Ribrag
Pages: 577-591
Published online: 30 Nov 2022
AbstractforUpdates in the Treatment of Peripheral T-Cell Lymphomas | Full Text | References | PDF (303.3 KB) | EPUB
  • 216 Views
  • 7 CrossRef citations
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Open Access
Review Article
Experimental Drugs for Chemotherapy- and Cancer-Related Anemia
Clelia Madeddu, Manuela Neri, Elisabetta Sanna, Sara Oppi & Antonio Macciò
Pages: 593-611
Published online: 24 Jun 2021
AbstractforExperimental Drugs for Chemotherapy- and Cancer-Related Anemia | Full Text | References | PDF (2.3 MB) | EPUB
  • 647 Views
  • 8 CrossRef citations
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Open Access

Original Research

Article
RETRACTED ARTICLE: Investigation of Antibacterial and Anti-Diarrhoeal Activities of 80% Methanol Leaf and Fruit Extract of Leonotis ocymifolia (Burm. F) Iwarsson (Lamiaceae)
Teklie Mengie Ayele, Endeshaw Chekol Abebe & Achenef Bogale Kassie
Pages: 613-626
Published online: 29 Jun 2021
AbstractforRETRACTED ARTICLE: Investigation of Antibacterial and Anti-Diarrhoeal Activities of 80% Methanol Leaf and Fruit Extract of Leonotis ocymifolia (Burm. F) Iwarsson (Lamiaceae) | PDF (493.9 KB)
  • 38 Views
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Review

Review Article
Promising Treatment Options for Axial Spondyloarthritis: An Overview of Experimental Pharmacological Agents
Hasan Tahir, Swetha Byravan, Armin Fardanesh & Arumugam Moorthy
Pages: 627-635
Published online: 30 Nov 2022
AbstractforPromising Treatment Options for Axial Spondyloarthritis: An Overview of Experimental Pharmacological Agents | Full Text | References | PDF (1.9 MB) | EPUB
  • 179 Views
  • 2 CrossRef citations
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Original Research

Article
The Effects of Furosemide on Behavioral and Hormonal Parameters in Male and Female Mice Subjected to Immobilization and Cold-Water Stress
Mohammed Al Za’abi, Badreldin H Ali, Yousuf Al Suleimani, Ibrahim Al-Zakwani, Balqees Al-Fulaiti, Priyadarsini Manoj & Abderrahim Nemmar
Pages: 637-643
Published online: 05 Jul 2021
AbstractforThe Effects of Furosemide on Behavioral and Hormonal Parameters in Male and Female Mice Subjected to Immobilization and Cold-Water Stress | Full Text | References | PDF (222.8 KB) | EPUB
  • 151 Views
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Open Access

Review

Review Article
Experimental Antiviral Therapeutic Studies for Human Rhinovirus Infections
James A Coultas, John Cafferkey, Patrick Mallia & Sebastian L Johnston
Pages: 645-659
Published online: 30 Nov 2022
AbstractforExperimental Antiviral Therapeutic Studies for Human Rhinovirus Infections | Full Text | References | PDF (802.5 KB) | EPUB
  • 525 Views
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Original Research

Article
Evaluation of the Antimalarial Activity of Ethanol Extracts of the Leaves of Three Plant Species Collected from Yayu Coffee Forest Biosphere Reserve, Southwest Ethiopia
Solomon Yeshanew, Worke Gete & Desalegn Chilo
Pages: 661-668
Published online: 30 Nov 2022
AbstractforEvaluation of the Antimalarial Activity of Ethanol Extracts of the Leaves of Three Plant Species Collected from Yayu Coffee Forest Biosphere Reserve, Southwest Ethiopia | Full Text | References | PDF (406.6 KB) | EPUB
  • 148 Views
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Open Access
Article
Antidiarrheal Effect of DLBS1Y62, a Bioactive Fraction of Uncaria gambir Roxb. Dried Sap Extract, in Wistar Rats
Dicky A Wibowo, Florensia Nailufar & Raymond R Tjandrawinata
Pages: 669-675
Published online: 15 Jul 2021
AbstractforAntidiarrheal Effect of DLBS1Y62, a Bioactive Fraction of Uncaria gambir Roxb. Dried Sap Extract, in Wistar Rats | Full Text | References | PDF (950 KB) | EPUB
  • 219 Views
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Article
Evaluation of Wound Healing Activity of Methanolic Crude Extract and Solvent Fractions of the Leaves of Vernonia auriculifera Hiern (Asteraceae) in Mice
Mulatu Kotiso Lambebo, Zemene Demelash Kifle, Tiruzer Bekele Gurji & Jibril Seid Yesuf
Pages: 677-692
Published online: 30 Nov 2022
AbstractforEvaluation of Wound Healing Activity of Methanolic Crude Extract and Solvent Fractions of the Leaves of Vernonia auriculifera Hiern (Asteraceae) in Mice | Full Text | References | PDF (2.9 MB) | EPUB
  • 679 Views
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Review

Review Article
Pharmacological Modulation of Ion Channels for the Treatment of Cystic Fibrosis
Madalena C Pinto, Iris A L Silva, Miriam F Figueira, Margarida D Amaral & Miquéias Lopes-Pacheco
Pages: 693-723
Published online: 30 Nov 2022
AbstractforPharmacological Modulation of Ion Channels for the Treatment of Cystic Fibrosis | Full Text | References | PDF (5.7 MB) | EPUB
  • 5982 Views
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Review Article
Experimental Pharmacological Management of Psoriasis
Elena Campione, Terenzio Cosio, Monia Di Prete, Caterina Lanna, Annunziata Dattola & Luca Bianchi
Pages: 725-737
Published online: 26 Jul 2021
AbstractforExperimental Pharmacological Management of Psoriasis | Full Text | References | PDF (1.7 MB) | EPUB
  • 470 Views
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Original Research

Article
Preclinical Evaluation of the Antihypertensive Effect of an Aqueous Extract of Anogeissus leiocarpa (DC) Guill et Perr. Bark of Trunk in L-NAME-Induced Hypertensive Rat
Lazare Belemnaba, Mathieu Nitiéma, Sylvain Ilboudo, Gueswindé Geoffroy Ouédraogo, Noufou Ouédraogo, Mohamed Bonewendé Belemlilga, Souleymane Compaoré, Salfo Ouédraogo & Sylvin Ouédraogo
Pages: 739-754
Published online: 07 Aug 2021
AbstractforPreclinical Evaluation of the Antihypertensive Effect of an Aqueous Extract of Anogeissus leiocarpa (DC) Guill et Perr. Bark of Trunk in L-NAME-Induced Hypertensive Rat | Full Text | References | PDF (9.6 MB) | EPUB
  • 246 Views
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Review

Review Article
An Overview of Investigational and Experimental Drug Treatment Strategies for Marfan Syndrome
Violette Deleeuw, Adelbert De Clercq, Julie De Backer & Patrick Sips
Pages: 755-779
Published online: 11 Aug 2021
AbstractforAn Overview of Investigational and Experimental Drug Treatment Strategies for Marfan Syndrome | Full Text | References | PDF (6.5 MB) | EPUB
  • 737 Views
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Open Access

Original Research

Article
Potential Antiaging Effects of DLBS1649, a Centella asiatica Bioactive Extract
Agung H Karsono, Olivia M Tandrasasmita, Guntur Berlian & Raymond R Tjandrawinata
Pages: 781-795
Published online: 30 Nov 2022
AbstractforPotential Antiaging Effects of DLBS1649, a Centella asiatica Bioactive Extract | Full Text | References | PDF (9.5 MB) | EPUB
  • 450 Views
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Article
Application of Topical Sucralfate and Topical Platelet-Rich Plasma Improves Wound Healing in Diabetic Ulcer Rats Wound Model
Renni Yuniati, Innelya Innelya, Arti Rachmawati, Harold Jefferson Matthew Charlex, Alfi Rahmatika, Matthew Brian Khrisna, Farmaditya E P Mundhofir, K Heri Nugroho Hario Seno & Tri Nur Kristina
Pages: 797-806
Published online: 14 Aug 2021
AbstractforApplication of Topical Sucralfate and Topical Platelet-Rich Plasma Improves Wound Healing in Diabetic Ulcer Rats Wound Model | Full Text | References | PDF (3.7 MB) | EPUB
  • 299 Views
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Review

Review Article
A Systematic Review on Traditional Medicinal Plants Used for the Treatment of Viral and Fungal Infections in Ethiopia
Yibeltal Aschale, Muluken Wubetu, Abtie Abebaw, Tadesse Yirga, Awoke Minwuyelet & Milkiyas Toru
Pages: 807-815
Published online: 16 Aug 2021
AbstractforA Systematic Review on Traditional Medicinal Plants Used for the Treatment of Viral and Fungal Infections in Ethiopia | Full Text | References | PDF (533 KB) | EPUB
  • 869 Views
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Review Article
Novel Experimental Therapies for Treatment of Pulmonary Arterial Hypertension
Ronald Zolty
Pages: 817-857
Published online: 17 Aug 2021
AbstractforNovel Experimental Therapies for Treatment of Pulmonary Arterial Hypertension | Full Text | References | PDF (2 MB) | EPUB
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Original Research

Article
Evaluation of Antidiabetic and Antioxidant Activity of Leaf Extract and Solvent Fractions of Hypoestes forskaolii (Val) (Acanthaceae) in Mice
Wakuma Wakene, Solomon Asmamaw & Wubayehu Kahaliw
Pages: 859-872
Published online: 22 Aug 2021
AbstractforEvaluation of Antidiabetic and Antioxidant Activity of Leaf Extract and Solvent Fractions of Hypoestes forskaolii (Val) (Acanthaceae) in Mice | Full Text | References | PDF (555.2 KB) | EPUB
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Article
Nanocurcumin Modulates miR-223-3p and NF-κB Levels in the Pancreas of Rat Model of Polycystic Ovary Syndrome to Attenuate Autophagy Flare, Insulin Resistance and Improve ß Cell Mass
Nermeen Z Abuelezz, Marwa E Shabana, Laila Rashed & George NB Morcos
Pages: 873-888
Published online: 26 Aug 2021
AbstractforNanocurcumin Modulates miR-223-3p and NF-κB Levels in the Pancreas of Rat Model of Polycystic Ovary Syndrome to Attenuate Autophagy Flare, Insulin Resistance and Improve ß Cell Mass | Full Text | References | PDF (7.8 MB) | EPUB
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Article
Evaluation of the Antimicrobial Activity of Leaf Extracts of Acokanthera schimperi against Various Disease-Causing Bacteria
Ambaye Kenubih, Eyerusalem Belay & Kumneger Lemma
Pages: 889-899
Published online: 07 Sep 2021
AbstractforEvaluation of the Antimicrobial Activity of Leaf Extracts of Acokanthera schimperi against Various Disease-Causing Bacteria | Full Text | References | PDF (946.4 KB) | EPUB
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Commentary

Article Commentary
Silibinin: A New Opportunity for the Treatment of Brain Metastasis from Lung Cancer
Raffaele Addeo
Pages: 901-903
Published online: 27 Sep 2021
AbstractforSilibinin: A New Opportunity for the Treatment of Brain Metastasis from Lung Cancer | Full Text | References | PDF (219 KB) | EPUB
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Review

Review Article
Current and Future Anti-VEGF Agents for Neovascular Age-Related Macular Degeneration
Stephanie M Kaiser, Sruthi Arepalli & Justis P Ehlers
Pages: 905-912
Published online: 29 Sep 2021
AbstractforCurrent and Future Anti-VEGF Agents for Neovascular Age-Related Macular Degeneration | Full Text | References | PDF (340 KB) | EPUB
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Original Research

Article
Preclinical Efficacy and Safety Studies of Formulation SSV-003, a Potent Anti-Viral Herbal Formulation
Yogesh Arun Dound & Rajesh Sehgal
Pages: 913-921
Published online: 22 Oct 2021
AbstractforPreclinical Efficacy and Safety Studies of Formulation SSV-003, a Potent Anti-Viral Herbal Formulation | Full Text | References | PDF (1.4 MB) | EPUB
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Review

Review Article
The Role of BTK Inhibition in the Treatment of Chronic Lymphocytic Leukemia: A Clinical View
Francesco Paolo Tambaro, Danilo De Novellis & William G Wierda
Pages: 923-935
Published online: 29 Oct 2021
AbstractforThe Role of BTK Inhibition in the Treatment of Chronic Lymphocytic Leukemia: A Clinical View | Full Text | References | PDF (1.5 MB) | EPUB
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Original Research

Article
Divya-Herbal-Peya Decoction Harmonizes the Inflammatory Response in Lipopolysaccharide-Induced Zebrafish Model
Acharya Balkrishna, Savita Lochab, Monali Joshi, Jyotish Srivastava & Anurag Varshney
Pages: 937-955
Published online: 02 Dec 2021
AbstractforDivya-Herbal-Peya Decoction Harmonizes the Inflammatory Response in Lipopolysaccharide-Induced Zebrafish Model | Full Text | References | PDF (8.4 MB) | EPUB
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Article
Aspirin as an Adjunctive Pharmacologic Therapy Option for COVID-19: Anti-Inflammatory, Antithrombotic, and Antiviral Effects All in One Agent
Udaya S Tantry, Karsten Schror, Eliano Pio Navarese, Young-Hoon Jeong, Jacek Kubica, Kevin P Bliden & Paul A Gurbel
Pages: 957-970
Published online: 07 Dec 2021
AbstractforAspirin as an Adjunctive Pharmacologic Therapy Option for COVID-19: Anti-Inflammatory, Antithrombotic, and Antiviral Effects All in One Agent | Full Text | References | PDF (2.3 MB) | EPUB
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Article
In Vitro Cytotoxicity and Anti-HIV Activity of Crude Extracts of Croton macrostachyus, Croton megalocarpus and Croton dichogamus
Ermias Mergia Terefe, Faith Apolot Okalebo, Solomon Derese, Joseph Muriuki & Gaber El-Saber Batiha
Pages: 971-979
Published online: 22 Dec 2021
AbstractforIn Vitro Cytotoxicity and Anti-HIV Activity of Crude Extracts of Croton macrostachyus, Croton megalocarpus and Croton dichogamus | Full Text | References | PDF (3.2 MB) | EPUB
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