Journal of Hepatocellular Carcinoma, Volume 7, Issue (2020)

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Journal of Hepatocellular Carcinoma, Volume 7, Issue (2020)

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Original Research

Article
Exploring Metabolic Consequences of CPS1 and CAD Dysregulation in Hepatocellular Carcinoma by Network Reconstruction
Ozbil E Dumenci, Abellona MR U, Shahid A Khan, Elaine Holmes & Simon D Taylor-Robinson
Pages: 1-9
Published online: 07 Jan 2020
AbstractforExploring Metabolic Consequences of CPS1 and CAD Dysregulation in Hepatocellular Carcinoma by Network Reconstruction | Full Text | References | PDF (2.9 MB) | EPUB
  • 118 Views
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Open Access

Review

Review Article
The Immune Modulation Effect of Locoregional Therapies and Its Potential Synergy with Immunotherapy in Hepatocellular Carcinoma
Prabhsimranjot Singh, Sudhamshi Toom, Akshay Avula, Vivek Kumar & Osama E Rahma
Pages: 11-17
Published online: 10 Feb 2020
AbstractforThe Immune Modulation Effect of Locoregional Therapies and Its Potential Synergy with Immunotherapy in Hepatocellular Carcinoma | Full Text | References | PDF (491.1 KB) | EPUB
  • 189 Views
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Open Access

Original Research

Article
Experimental Study of Hepatocellular Carcinoma Treatment by Shikonin Through Regulating PKM2
Tong Liu, Sainan Li, Liwei Wu, Qiang Yu, Jingjing Li, Jiao Feng, Jie Zhang, Jiaojiao Chen, Yuting Zhou, Jie Ji, Kan Chen, Yuqing Mao, Fan Wang, Weiqi Dai, Xiaoming Fan, Jianye Wu & Chuanyong Guo
Pages: 19-31
Published online: 18 Feb 2020
AbstractforExperimental Study of Hepatocellular Carcinoma Treatment by Shikonin Through Regulating PKM2 | Full Text | References | PDF (7.9 MB) | EPUB
  • 174 Views
  • 26 CrossRef citations
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Open Access

Review

Review Article
Impact of Next-Generation Sequencing on Outcomes in Hepatocellular Carcinoma: How Precise Are We Really?
Dana A Dominguez & Xin Wei Wang
Pages: 33-37
Published online: 19 Mar 2020
AbstractforImpact of Next-Generation Sequencing on Outcomes in Hepatocellular Carcinoma: How Precise Are We Really? | Full Text | References | PDF (1.3 MB) | EPUB
  • 144 Views
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Open Access

Case Report

Case Report
Rare Site Hepatocellular Carcinoma Metastasis
Enrique Boldo, Ana Santafe, Araceli Mayol, Rafael Lozoya, Alba Coret, Diana Escribano, Carlos Fortea-Sanchis, Andres Muñoz, Juan Carlos Pastor, Guillermo Perez de Lucia & Nuria Bosch
Pages: 39-44
Published online: 25 Mar 2020
AbstractforRare Site Hepatocellular Carcinoma Metastasis | Full Text | References | PDF (1.8 MB) | EPUB
  • 95 Views
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Open Access

Review

Review Article
Hepatocellular Carcinoma Mechanisms Associated with Chronic HCV Infection and the Impact of Direct-Acting Antiviral Treatment
Srikanta Dash, Yucel Aydin, Kyle E Widmer & Leela Nayak
Pages: 45-76
Published online: 15 Apr 2020
AbstractforHepatocellular Carcinoma Mechanisms Associated with Chronic HCV Infection and the Impact of Direct-Acting Antiviral Treatment | Full Text | References | PDF (5.3 MB) | EPUB
  • 582 Views
  • 49 CrossRef citations
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Open Access
Review Article
Angiogenesis in Hepatocellular Carcinoma; Pathophysiology, Targeted Therapy, and Role of Imaging
Ahmed W Moawad, Janio Szklaruk, Chandana Lall, Katherine J Blair, Ahmed O Kaseb, Amita Kamath, Scott A Rohren & Khaled M Elsayes
Pages: 77-89
Published online: 23 Apr 2020
AbstractforAngiogenesis in Hepatocellular Carcinoma; Pathophysiology, Targeted Therapy, and Role of Imaging | Full Text | References | PDF (4.9 MB) | EPUB
  • 523 Views
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Open Access
Review Article
Profile of Cabozantinib for the Treatment of Hepatocellular Carcinoma: Patient Selection and Special Considerations
Audrey Debaillon Vesque, Marie Decraecker & Jean-Frédéric Blanc
Pages: 91-99
Published online: 09 Jun 2020
AbstractforProfile of Cabozantinib for the Treatment of Hepatocellular Carcinoma: Patient Selection and Special Considerations | Full Text | References | PDF (402.4 KB) | EPUB
  • 96 Views
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Open Access

Original Research

Article
Inflammation-Based Prognostic Scores in Patients with Hepatitis B Virus-Related Hepatocellular Carcinoma After Liver Transplantation
Ao Ren, Zhongqiu Li, Xuzhi Zhang, Ronghai Deng & Yi Ma
Pages: 101-106
Published online: 07 Jul 2020
AbstractforInflammation-Based Prognostic Scores in Patients with Hepatitis B Virus-Related Hepatocellular Carcinoma After Liver Transplantation | Full Text | References | PDF (1.1 MB) | EPUB
  • 116 Views
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Open Access

Review

Review Article
Resection of NAFLD-Associated HCC: Patient Selection and Reported Outcomes
Claudia Campani, Carolina Bensi, Stefano Milani, Andrea Galli & Mirko Tarocchi
Pages: 107-116
Published online: 30 Jul 2020
AbstractforResection of NAFLD-Associated HCC: Patient Selection and Reported Outcomes | Full Text | References | PDF (1.4 MB) | EPUB
  • 123 Views
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Open Access

Original Research

Article
Survival Outcomes for Yttrium-90 Transarterial Radioembolization With and Without Sorafenib for Unresectable Hepatocellular Carcinoma Patients
Ajalaya Teyateeti, Armeen Mahvash, James P Long, Mohamed E Abdelsalam, Rony Avritscher, Beth Chasen, Ahmed O Kaseb, Joshua D Kuban, Ravi Murthy, Bruno C Odisio, Achiraya Teyateeti, Homer A Macapinlac & S Cheenu Kappadath
Pages: 117-131
Published online: 14 Sep 2020
AbstractforSurvival Outcomes for Yttrium-90 Transarterial Radioembolization With and Without Sorafenib for Unresectable Hepatocellular Carcinoma Patients | Full Text | References | PDF (1.8 MB) | EPUB
  • 138 Views
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Open Access

Review

Review Article
Combination Antiangiogenic and Immunotherapy for Advanced Hepatocellular Carcinoma: Evidence to Date
Alison L Raybould & Hanna Sanoff
Pages: 133-142
Published online: 15 Sep 2020
AbstractforCombination Antiangiogenic and Immunotherapy for Advanced Hepatocellular Carcinoma: Evidence to Date | Full Text | References | PDF (866 KB) | EPUB
  • 181 Views
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Open Access

Original Research

Article
Prognostic Significance of Serum Insulin-Like Growth Factor-1 in Hepatocellular Cancer Patients: A Validation Study
Sahin Lacin, Suayib Yalcin, Yusuf Karakas, Manal M Hassan, Hesham Amin, Yehia Ibrahim Mohamed, Asif Rashid, Jeffrey S Morris, Lianchun Xiao, Aliya Qayyum & Ahmed O Kaseb
Pages: 143-153
Published online: 16 Sep 2020
AbstractforPrognostic Significance of Serum Insulin-Like Growth Factor-1 in Hepatocellular Cancer Patients: A Validation Study | Full Text | References | PDF (1.4 MB) | EPUB
  • 94 Views
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Open Access

Expert Opinion

Article Commentary
Surgical Management of Localized Hepatocellular Carcinoma in Times of Crisis: A Strategic Approach to Resource Utilization
Hop Tran Cao, Ching-Wei Tzeng, Yun Shin Chun, Thomas Aloia & Jean Nicolas Vauthey
Pages: 155-158
Published online: 28 Sep 2020
AbstractforSurgical Management of Localized Hepatocellular Carcinoma in Times of Crisis: A Strategic Approach to Resource Utilization | Full Text | References | PDF (224.4 KB) | EPUB
  • 92 Views
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Open Access

Original Research

Article
Amide Proton Transfer Imaging vs Diffusion Kurtosis Imaging for Predicting Histological Grade of Hepatocellular Carcinoma
Baolin Wu, Fei Jia, Xuekun Li, Meng Zhang, Dongming Han & Zhiyun Jia
Pages: 159-168
Published online: 09 Oct 2020
AbstractforAmide Proton Transfer Imaging vs Diffusion Kurtosis Imaging for Predicting Histological Grade of Hepatocellular Carcinoma | Full Text | References | PDF (3.4 MB) | EPUB
  • 105 Views
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Open Access
Article
The Clinicopathological and Imaging Characteristics of Primary Hepatic Carcinosarcoma and a Review of the Literature
Fengli Bin, Zhihong Chen, Peng Liu, Jianbin Liu & Zhiqun Mao
Pages: 169-180
Published online: 13 Oct 2020
AbstractforThe Clinicopathological and Imaging Characteristics of Primary Hepatic Carcinosarcoma and a Review of the Literature | Full Text | References | PDF (2.4 MB) | EPUB
  • 131 Views
  • 3 CrossRef citations
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Open Access
Article
Drug-eluting Bead-Transcatheter Arterial Chemoembolization for Advanced Hepatocellular Carcinoma Refractory to Conventional Lipiodol-based Transcatheter Arterial Chemoembolization
Saito Kobayashi, Kazuto Tajiri, Aiko Murayama, Toshiki Entani, Yuka Futsukaichi, Kohei Nagata, Kosuke Takahashi & Ichiro Yasuda
Pages: 181-189
Published online: 14 Oct 2020
AbstractforDrug-eluting Bead-Transcatheter Arterial Chemoembolization for Advanced Hepatocellular Carcinoma Refractory to Conventional Lipiodol-based Transcatheter Arterial Chemoembolization | Full Text | References | PDF (3.2 MB) | EPUB
  • 104 Views
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Open Access
Article
Elevated Platelet Count is Associated with Poor Survival After Transarterial Chemoembolization Treatment in Patients with Hepatocellular Carcinoma: A Cohort Study
linbin Lu, Yan Zhang, Peichan Zheng, Zhixian Wu, Xuewen Wang, Yaying Chen & Xiong Chen
Pages: 191-199
Published online: 15 Oct 2020
AbstractforElevated Platelet Count is Associated with Poor Survival After Transarterial Chemoembolization Treatment in Patients with Hepatocellular Carcinoma: A Cohort Study | Full Text | References | PDF (2.4 MB) | EPUB
  • 100 Views
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Open Access
Article
Assessing the Survival Benefit of Surgery and Various Types of Radiation Therapy for Treatment of Hepatocellular Carcinoma: Evidence from the Surveillance, Epidemiology, and End Results Registries
Fuyan Shi, Chen Wang, Yujia Kong, Liping Yang, Juan Li, Gaopei Zhu, Jing Guo, Qingfeng Zheng, Bo Zhang & Suzhen Wang
Pages: 201-218
Published online: 19 Oct 2020
AbstractforAssessing the Survival Benefit of Surgery and Various Types of Radiation Therapy for Treatment of Hepatocellular Carcinoma: Evidence from the Surveillance, Epidemiology, and End Results Registries | Full Text | References | PDF (426.2 KB) | EPUB
  • 113 Views
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Open Access
Article
Validation of the GALAD Model and Establishment of GAAP Model for Diagnosis of Hepatocellular Carcinoma in Chinese Patients
Miaoxia Liu, Ruihong Wu, Xu Liu, Hongqin Xu, Xiumei Chi, Xiaomei Wang, Mengru Zhan, Bao Wang, Fei Peng, Xiuzhu Gao, Ying Shi, Xiaoyu Wen, Yali Ji, Qinglong Jin & Junqi Niu
Pages: 219-232
Published online: 23 Oct 2020
AbstractforValidation of the GALAD Model and Establishment of GAAP Model for Diagnosis of Hepatocellular Carcinoma in Chinese Patients | Full Text | References | PDF (997.7 KB) | EPUB
  • 170 Views
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Open Access
Article
Prognostic Nomograms for Patients with Hepatocellular Carcinoma After Curative Hepatectomy, with a Focus on Recurrence Timing and Post-Recurrence Management
Wei Xu, Fei Liu, Xianbo Shen & Ruineng Li
Pages: 233-256
Published online: 27 Oct 2020
AbstractforPrognostic Nomograms for Patients with Hepatocellular Carcinoma After Curative Hepatectomy, with a Focus on Recurrence Timing and Post-Recurrence Management | Full Text | References | PDF (5 MB) | EPUB
  • 89 Views
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Open Access
Article
miR-3 Encoded by Hepatitis B Virus Downregulates PTEN Protein Expression and Promotes Cell Proliferation
Jian Tang, Xinqiang Xiao, Yongfang Jiang, Yi Tian, Zhongtian Peng, Meichan Yang, Zhenyu Xu & Guozhong Gong
Pages: 257-269
Published online: 29 Oct 2020
AbstractformiR-3 Encoded by Hepatitis B Virus Downregulates PTEN Protein Expression and Promotes Cell Proliferation | Full Text | References | PDF (8 MB) | EPUB
  • 150 Views
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Open Access

Review

Review Article
Gut Microbiota, Peroxisome Proliferator-Activated Receptors, and Hepatocellular Carcinoma
Qiang Yu, Liwei Wu, Jie Ji, Jiao Feng, Weiqi Dai, Jingjing Li, Jianye Wu & Chuanyong Guo
Pages: 271-288
Published online: 29 Oct 2020
AbstractforGut Microbiota, Peroxisome Proliferator-Activated Receptors, and Hepatocellular Carcinoma | Full Text | References | PDF (1.6 MB) | EPUB
  • 221 Views
  • 11 CrossRef citations
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Open Access

Original Research

Article
Association of the Pretreatment Lung Immune Prognostic Index with Survival Outcomes in Advanced Hepatocellular Carcinoma Patients Treated with PD-1 Inhibitors
Shixue Chen, Ziwei Huang, Wangping Jia, Haitao Tao, Sujie Zhang, Junxun Ma, Zhefeng Liu, Jinliang Wang, Lijie Wang, Pengfei Cui, Zhibo Zhang, Di Huang, Zhaozhen Wu, Xuan Zheng & Yi Hu
Pages: 289-299
Published online: 02 Nov 2020
AbstractforAssociation of the Pretreatment Lung Immune Prognostic Index with Survival Outcomes in Advanced Hepatocellular Carcinoma Patients Treated with PD-1 Inhibitors | Full Text | References | PDF (1.6 MB) | EPUB
  • 96 Views
  • 12 CrossRef citations
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Open Access
Article
Cross-Linked Multimeric Pro-Peptides of Type III Collagen (PC3X) in Hepatocellular Carcinoma – A Biomarker That Provides Additional Prognostic Value in AFP Positive Patients
Christina Jensen, Signe Holm Nielsen, Mohammed Eslam, Federica Genovese, Mette Juul Nielsen, Roslyn Vongsuvanh, Raj Uchila, David van der Poorten, Jacob George, Morten Asser Karsdal, Diana Julie Leeming & Nicholas Willumsen
Pages: 301-313
Published online: 09 Nov 2020
AbstractforCross-Linked Multimeric Pro-Peptides of Type III Collagen (PC3X) in Hepatocellular Carcinoma – A Biomarker That Provides Additional Prognostic Value in AFP Positive Patients | Full Text | References | PDF (3.5 MB) | EPUB
  • 124 Views
  • 12 CrossRef citations
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Open Access
Article
Development and Verification of the Hypoxia-Related and Immune-Associated Prognosis Signature for Hepatocellular Carcinoma
Bo Hu, Xiao-Bo Yang & Xin-Ting Sang
Pages: 315-330
Published online: 11 Nov 2020
AbstractforDevelopment and Verification of the Hypoxia-Related and Immune-Associated Prognosis Signature for Hepatocellular Carcinoma | Full Text | References | PDF (9 MB) | EPUB
  • 159 Views
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Open Access
Article
Value of Follow-Up Chest Computed Tomography in the Surveillance of Patients with Hepatocellular Carcinoma
Ahmed W Moawad, Khaled M Elsayes, Farah Benamar, Kundan Rao, Jia Sun & Janio Szklaruk
Pages: 331-335
Published online: 18 Nov 2020
AbstractforValue of Follow-Up Chest Computed Tomography in the Surveillance of Patients with Hepatocellular Carcinoma | Full Text | References | PDF (306.5 KB) | EPUB
  • 99 Views
  • 1 CrossRef citations
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Open Access
Article
Baseline HBV Loads Do Not Affect the Prognosis of Patients with Hepatocellular Carcinoma Receiving Anti-Programmed Cell Death-1 Immunotherapy
Xuqi Sun, Dandan Hu, Zhoutian Yang, Zheng Liu, Juncheng Wang, Jinbin Chen, Li Xu, Zhongguo Zhou, Minshan Chen & Yaojun Zhang
Pages: 337-345
Published online: 01 Dec 2020
AbstractforBaseline HBV Loads Do Not Affect the Prognosis of Patients with Hepatocellular Carcinoma Receiving Anti-Programmed Cell Death-1 Immunotherapy | Full Text | References | PDF (3.7 MB) | EPUB
  • 127 Views
  • 3 CrossRef citations
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Open Access

Review

Review Article
Timing of DAA Initiation After Curative Treatment and Its Relationship with the Recurrence of HCV-Related HCC
Xiuzhu Gao, Mengru Zhan, Liquan Wang, Yanhua Ding & Junqi Niu
Pages: 347-360
Published online: 01 Dec 2020
AbstractforTiming of DAA Initiation After Curative Treatment and Its Relationship with the Recurrence of HCV-Related HCC | Full Text | References | PDF (361 KB) | EPUB
  • 121 Views
  • 8 CrossRef citations
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Open Access

Original Research

Article
Effects of LRP1B Regulated by HSF1 on Lipid Metabolism in Hepatocellular Carcinoma
Miaomiao Li, Juntao Hu, Riming Jin, Hongxia Cheng, Huaping Chen, Limin Li & Kun Guo
Pages: 361-376
Published online: 08 Dec 2020
AbstractforEffects of LRP1B Regulated by HSF1 on Lipid Metabolism in Hepatocellular Carcinoma | Full Text | References | PDF (7.7 MB) | EPUB
  • 181 Views
  • 11 CrossRef citations
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Open Access
Article
Can Immediately Treating Subcentimeter Hepatocellular Carcinoma Improve the Survival of Patients?
Xuqi Sun, Dandan Hu, Yaojun Zhang, Ning Lyu, Li Xu, Qifeng Chen, Jinfa Lai, Minshan Chen & Ming Zhao
Pages: 377-384
Published online: 16 Dec 2020
AbstractforCan Immediately Treating Subcentimeter Hepatocellular Carcinoma Improve the Survival of Patients? | Full Text | References | PDF (2 MB) | EPUB
  • 102 Views
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Open Access
Article
Increased Expression of Programmed Death Ligand 1 in Hepatocellular Carcinoma of Patients with Hepatitis B Virus Pre-S2 Mutant
Chiao-Fang Teng, Tsai-Chung Li, Ting Wang, Tzu-Hua Wu, John Wang, Han-Chieh Wu, Woei-Cherng Shyu, Ih-Jen Su & Long-Bin Jeng
Pages: 385-401
Published online: 17 Dec 2020
AbstractforIncreased Expression of Programmed Death Ligand 1 in Hepatocellular Carcinoma of Patients with Hepatitis B Virus Pre-S2 Mutant | Full Text | References | PDF (10.2 MB) | EPUB
  • 81 Views
  • 5 CrossRef citations
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Open Access
Article
Appraisal of Long-Term Outcomes of Liver-Directed Concurrent Chemoradiotherapy for Hepatocellular Carcinoma with Major Portal Vein Invasion
Sojung Han, Hye Won Lee, Jun Yong Park, Seung Up Kim, Do Young Kim, Sang Hoon Ahn, Kwang-Hyub Han, Jinsil Seong, Jong Yun Won, Dai Hoon Han & Beom Kyung Kim
Pages: 403-412
Published online: 17 Dec 2020
AbstractforAppraisal of Long-Term Outcomes of Liver-Directed Concurrent Chemoradiotherapy for Hepatocellular Carcinoma with Major Portal Vein Invasion | Full Text | References | PDF (811.4 KB) | EPUB
  • 102 Views
  • 6 CrossRef citations
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Open Access

Review

Review Article
Serum Tumor Markers for Early Diagnosis of Primary Hepatocellular Carcinoma
Jingjing Zong, Zhe Fan & Yewei Zhang
Pages: 413-422
Published online: 18 Dec 2020
AbstractforSerum Tumor Markers for Early Diagnosis of Primary Hepatocellular Carcinoma | Full Text | References | PDF (317.8 KB) | EPUB
  • 422 Views
  • 16 CrossRef citations
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Open Access

Expert Opinion

Article Commentary
Potential Impact of IMbrave150 Results in the Evolving Treatment Landscape of Advanced Hepatocellular Carcinoma: A Multidisciplinary Expert Opinion
Laura Kulik, Leonardo G da Fonseca, Aiwu Ruth He, Jordi Rimola, Andrea Wilson Woods, York F Zöllner & Peter R Galle
Pages: 423-433
Published online: 21 Dec 2020
AbstractforPotential Impact of IMbrave150 Results in the Evolving Treatment Landscape of Advanced Hepatocellular Carcinoma: A Multidisciplinary Expert Opinion | Full Text | References | PDF (310.8 KB) | EPUB
  • 122 Views
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Open Access

Review

Review Article
Efficacy of Local Treatments for Hepatocellular Carcinoma Involving the Inferior Vena Cava and/or Right Atrium
Han Ah Lee & Chai Hong Rim
Pages: 435-446
Published online: 21 Dec 2020
AbstractforEfficacy of Local Treatments for Hepatocellular Carcinoma Involving the Inferior Vena Cava and/or Right Atrium | Full Text | References | PDF (328.3 KB) | EPUB
  • 132 Views
  • 1 CrossRef citations
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Open Access

Original Research

Article
Effect of Inhibiting Tumor Angiogenesis After Embolization in the Treatment of HCC with Apatinib-Loaded p(N-Isopropyl-Acrylamide-co-Butyl Methyl Acrylate) Temperature-Sensitive Nanogel
Chen Zhou, Qin Shi, Jiacheng Liu, Songjiang Huang, Chongtu Yang & Bin Xiong
Pages: 447-456
Published online: 31 Dec 2020
AbstractforEffect of Inhibiting Tumor Angiogenesis After Embolization in the Treatment of HCC with Apatinib-Loaded p(N-Isopropyl-Acrylamide-co-Butyl Methyl Acrylate) Temperature-Sensitive Nanogel | Full Text | References | PDF (3.4 MB) | EPUB
  • 127 Views
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