OncoTargets and Therapy, Volume 7, Issue (2014)

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OncoTargets and Therapy, Volume 7, Issue (2014)

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Case Report

Case Report
Primary malignant fibrous histiocytoma of the renal pelvis: a 78-month follow-up case report
YueBing Chen, Dapang Rao, Haibo Zhu, Haifeng Yu & ShiKun Yang
Pages: 1-3
Published online: 17 Dec 2013
AbstractforPrimary malignant fibrous histiocytoma of the renal pelvis: a 78-month follow-up case report | Full Text | References | PDF (1.1 MB)
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Open Access

Original Research

Article
The -159C/T polymorphism in the CD14 gene and cancer risk: a meta-analysis
Wei Zhou, Liuqun Jia, Shujin Guo, Qianjin Hu, Yongchun Shen & Ningxiu Li
Pages: 5-12
Published online: 10 Dec 2013
AbstractforThe -159C/T polymorphism in the CD14 gene and cancer risk: a meta-analysis | Full Text | References | PDF (837.4 KB)
  • 59 Views
  • 1 CrossRef citations
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Open Access
Article
Management of cytopenias in patients with myelofibrosis treated with ruxolitinib and effect of dose modifications on efficacy outcomes
Srdan Verstovsek, Jason Gotlib, Vikas Gupta, Ehab Atallah, John Mascarenhas, Alfonso Quintas-Cardama, William Sun, Nicholas J Sarlis, Victor Sandor, Richard S Levy, Hagop M Kantarjian & Ruben A Mesa
Pages: 13-21
Published online: 17 Dec 2013
AbstractforManagement of cytopenias in patients with myelofibrosis treated with ruxolitinib and effect of dose modifications on efficacy outcomes | Full Text | References | PDF (328.6 KB)
  • 171 Views
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Open Access
Article
hnRNP C1/C2 and Pur-beta proteins mediate induction of senescence by oligonucleotides homologous to the telomere overhang
Richard E Mulnix, Ryan T Pitman, Allison Retzer, Ceyda Bertram, Kavin Arasi, Zachary Crees, Jennifer Girard, Srijayaprakash B Uppada, Amanda L Stone & Neelu Puri
Pages: 23-32
Published online: 18 Dec 2013
AbstractforhnRNP C1/C2 and Pur-beta proteins mediate induction of senescence by oligonucleotides homologous to the telomere overhang | Full Text | References | PDF (1 MB)
  • 65 Views
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Open Access

Review

Review Article
Emerging concepts in pancreatic cancer medicine: targeting the tumor stroma
Albrecht Neesse, Sebastian Krug, Thomas M Gress, David A Tuveson & Patrick Michl
Pages: 33-43
Published online: 18 Dec 2013
AbstractforEmerging concepts in pancreatic cancer medicine: targeting the tumor stroma | Full Text | References | PDF (675.8 KB)
  • 119 Views
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Open Access
Review Article
Targeted therapy for Hodgkin lymphoma and systemic anaplastic large cell lymphoma: focus on brentuximab vedotin
Xueyan Chen, Lorinda A Soma & Jonathan R Fromm
Pages: 45-56
Published online: 19 Dec 2013
AbstractforTargeted therapy for Hodgkin lymphoma and systemic anaplastic large cell lymphoma: focus on brentuximab vedotin | Full Text | References | PDF (752.7 KB)
  • 142 Views
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Open Access
Review Article
Uncovering the role of p53 splice variants in human malignancy: a clinical perspective
Sylvanie Surget, Marie P Khoury & Jean-Christophe Bourdon
Pages: 57-68
Published online: 19 Dec 2013
AbstractforUncovering the role of p53 splice variants in human malignancy: a clinical perspective | Full Text | References | PDF (373.5 KB)
  • 287 Views
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Open Access
Review Article
Ocular side effects of biological agents in oncology: what should the clinician be aware of?
Tobias Hager & B Seitz
Pages: 69-77
Published online: 24 Dec 2013
AbstractforOcular side effects of biological agents in oncology: what should the clinician be aware of? | Full Text | References | PDF (824.6 KB)
  • 151 Views
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Open Access

Original Research

Article
High expression of Sonic Hedgehog signaling pathway genes indicates a risk of recurrence of breast carcinoma
Kuo-Shyang Jeng, I-Shyan Sheen, Wen-Juei Jeng, Ming-Che Yu, Hsin-I Hsiau & Fang-Yu Chang
Pages: 79-86
Published online: 27 Dec 2013
AbstractforHigh expression of Sonic Hedgehog signaling pathway genes indicates a risk of recurrence of breast carcinoma | Full Text | References | PDF (494 KB)
  • 112 Views
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Open Access

Case Report

Case Report
The long-term survival of a thymic carcinoma patient treated with S-1: a case report and literature review
Hisashi Tanaka, Takeshi Morimoto, Kageaki Taima, Yoshihito Tanaka, Kunihiko Nakamura, Akihito Hayashi, Akira Kurose, Ken Okumura & Shingo Takanashi
Pages: 87-90
Published online: 27 Dec 2013
AbstractforThe long-term survival of a thymic carcinoma patient treated with S-1: a case report and literature review | Full Text | References | PDF (1.3 MB)
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Open Access

Original Research

Article
Comparison of concurrent chemoradiotherapy followed by radical surgery and high-dose-rate intracavitary brachytherapy: a retrospective study of 240 patients with FIGO stage IIB cervical carcinoma
Ning Wang, Wei-Wei Li, Jian-Ping Li, Juan-Yue Liu, Yong-Chun Zhou, Ying Zhang, Jing Hu, Yan-Hong Huang, Yan Chen, Li-Chun Wei & Mei Shi
Pages: 91-100
Published online: 06 Jan 2014
AbstractforComparison of concurrent chemoradiotherapy followed by radical surgery and high-dose-rate intracavitary brachytherapy: a retrospective study of 240 patients with FIGO stage IIB cervical carcinoma | Full Text | References | PDF (362.9 KB)
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Open Access
Article
Effect of onion flavonoids on colorectal cancer with hyperlipidemia: an in vivo study
Yongshan He, Heiying Jin, Wei Gong, Chunxia Zhang & Acheng Zhou
Pages: 101-110
Published online: 08 Jan 2014
AbstractforEffect of onion flavonoids on colorectal cancer with hyperlipidemia: an in vivo study | Full Text | References | PDF (346.7 KB)
  • 116 Views
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Open Access

Case Series

Clear cell carcinoma of the uterine cervix: clinical characteristics and feasibility of fertility-preserving treatment
Xiang Jiang, Ying Jin, Yan Li, Hui-Fang Huang, Ming Wu, Keng Shen & Ling-Ya Pan
Pages: 111-116
Published online: 09 Jan 2014
AbstractforClear cell carcinoma of the uterine cervix: clinical characteristics and feasibility of fertility-preserving treatment | Full Text | References | PDF (1,000.9 KB)
  • 80 Views
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Open Access

Original Research

Article
Therapeutic targeting of Neu1 sialidase with oseltamivir phosphate (Tamiflu®) disables cancer cell survival in human pancreatic cancer with acquired chemoresistance
Leah K O’Shea, Samar Abdulkhalek, Stephanie Allison, Ronald J Neufeld & Myron R Szewczuk
Pages: 117-134
Published online: 16 Jan 2014
AbstractforTherapeutic targeting of Neu1 sialidase with oseltamivir phosphate (Tamiflu®) disables cancer cell survival in human pancreatic cancer with acquired chemoresistance | Full Text | References | PDF (4.5 MB)
  • 150 Views
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Open Access

Erratum

Correction
Clinical value of serum human epididymis protein 4 assay in the diagnosis of ovarian cancer: a meta-analysis [Erratum]
Page: 135
Published online: 23 Jan 2014
CitationforClinical value of serum human epididymis protein 4 assay in the diagnosis of ovarian cancer: a meta-analysis [Erratum] | Full Text | PDF (90.4 KB)
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Open Access

Original Research

Article
Combined overexpression of HIVEP3 and SOX9 predicts unfavorable biochemical recurrence-free survival in patients with prostate cancer
Guo-qiang Qin, Hui-chan He, Zhao-dong Han, Yu-xiang Liang, Sheng-bang Yang, Ya-qiang Huang, Liang Zhou, Hao Fu, Jie-xian Li, Fu-neng Jiang & Wei-de Zhong
Pages: 137-146
Published online: 24 Jan 2014
AbstractforCombined overexpression of HIVEP3 and SOX9 predicts unfavorable biochemical recurrence-free survival in patients with prostate cancer | Full Text | References | PDF (1.8 MB)
  • 97 Views
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Open Access

Review

Review Article
Triple-negative breast cancer risk in women is defined by the defect of estrogen signaling: preventive and therapeutic implications
Zsuzsanna Suba
Pages: 147-164
Published online: 23 Jan 2014
AbstractforTriple-negative breast cancer risk in women is defined by the defect of estrogen signaling: preventive and therapeutic implications | Full Text | References | PDF (387 KB)
  • 153 Views
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Open Access

Case Report

Case Report
Effective use of everolimus as salvage chemotherapy for ovarian clear cell carcinoma: a case report
Eriko Takatori, Tadahiro Shoji, Yuki Miura, Anna Takada, Satoshi Takeuchi & Toru Sugiyama
Pages: 165-169
Published online: 29 Jan 2014
AbstractforEffective use of everolimus as salvage chemotherapy for ovarian clear cell carcinoma: a case report | Full Text | References | PDF (752.6 KB)
  • 59 Views
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Open Access

Original Research

Article
Thoracotomy in refractory gestational trophoblastic neoplasia with lung metastasis after normalization of serum beta human chorionic gonadotropin (β-hCG) with salvage chemotherapy
Fengzhi Feng, Huiying Hu, Lei Wu, Tong Ren, Xirun Wan & Yang Xiang
Pages: 171-176
Published online: 29 Jan 2014
AbstractforThoracotomy in refractory gestational trophoblastic neoplasia with lung metastasis after normalization of serum beta human chorionic gonadotropin (β-hCG) with salvage chemotherapy | Full Text | References | PDF (278.1 KB)
  • 51 Views
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Open Access

Review

Review Article
Omacetaxine mepesuccinate in the treatment of intractable chronic myeloid leukemia
Yaoyu Chen & Shaoguang Li
Pages: 177-186
Published online: 02 Dec 2022
AbstractforOmacetaxine mepesuccinate in the treatment of intractable chronic myeloid leukemia | Full Text | References | PDF (432.4 KB)
  • 92 Views
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Open Access
Review Article
Nab-paclitaxel: potential for the treatment of advanced pancreatic cancer
Marwan Al-Hajeili, Asfar S Azmi & Minsig Choi
Pages: 187-192
Published online: 04 Feb 2014
AbstractforNab-paclitaxel: potential for the treatment of advanced pancreatic cancer | Full Text | References | PDF (184 KB)
  • 183 Views
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Original Research

Article
Dichloroacetate modulates cytokines toward T helper 1 function via induction of the interleukin-12–interferon-γ pathway
Mujtaba M Badr, Nidal A Qinna, Fadi Qadan & Khalid Z Matalka
Pages: 193-201
Published online: 07 Feb 2014
AbstractforDichloroacetate modulates cytokines toward T helper 1 function via induction of the interleukin-12–interferon-γ pathway | Full Text | References | PDF (1.2 MB)
  • 86 Views
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Open Access

Review

Review Article
Ipilimumab in the treatment of metastatic melanoma: management of adverse events
Giuseppina Della Vittoria Scarpati, Celeste Fusciello, Francesco Perri, Francesco Sabbatino, Soldano Ferrone, Chiara Carlomagno & Stefano Pepe
Pages: 203-209
Published online: 02 Dec 2022
AbstractforIpilimumab in the treatment of metastatic melanoma: management of adverse events | Full Text | References | PDF (415.4 KB)
  • 160 Views
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Original Research

Article
Midazolam induces apoptosis in MA-10 mouse Leydig tumor cells through caspase activation and the involvement of MAPK signaling pathway
Edmund Cheung So, Yu-Xuan Lin, Chi Hao Tseng, Bo-Syong Pan, Ka-Shun Cheng, Kar-Lok Wong, Lyh-Jyh Hao, Yang-Kao Wang & Bu-Miin Huang
Pages: 211-221
Published online: 13 Feb 2014
AbstractforMidazolam induces apoptosis in MA-10 mouse Leydig tumor cells through caspase activation and the involvement of MAPK signaling pathway | Full Text | References | PDF (1.6 MB)
  • 60 Views
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Open Access

Review Article

Review Article
Mechanism of action and clinical activity of tasquinimod in castrate-resistant prostate cancer
Neha Gupta, Omar Al Ustwani, Li Shen & Roberto Pili
Pages: 223-234
Published online: 12 Feb 2014
AbstractforMechanism of action and clinical activity of tasquinimod in castrate-resistant prostate cancer | Full Text | References | PDF (751 KB)
  • 104 Views
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Open Access

Review

Review Article
Treating malignant glioma in Chinese patients: update on temozolomide
Liang Chang, Jun Su, Xiuzhi Jia & Huan Ren
Pages: 235-244
Published online: 12 Feb 2014
AbstractforTreating malignant glioma in Chinese patients: update on temozolomide | Full Text | References | PDF (312.3 KB)
  • 117 Views
  • 6 CrossRef citations
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Open Access
Review Article
Targeted treatment of head and neck squamous-cell carcinoma: potential of lapatinib
Mitul D Gandhi & Mark Agulnik
Pages: 245-251
Published online: 13 Feb 2014
AbstractforTargeted treatment of head and neck squamous-cell carcinoma: potential of lapatinib | Full Text | References | PDF (214.7 KB)
  • 74 Views
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Open Access
Review Article
Role of erlotinib in the targeted treatment of non-small-cell lung cancer in Chinese patients
Wei Li, Fei Zhou & Caicun Zhou
Pages: 253-261
Published online: 13 Feb 2014
AbstractforRole of erlotinib in the targeted treatment of non-small-cell lung cancer in Chinese patients | Full Text | References | PDF (251.9 KB)
  • 66 Views
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Open Access
Review Article
The relationship between intervention in the CD40 signal pathway and choroidal neovascularization
Peipei Zhang, Yan Su & Fang Liu
Pages: 263-267
Published online: 02 Dec 2022
AbstractforThe relationship between intervention in the CD40 signal pathway and choroidal neovascularization | Full Text | References | PDF (172.4 KB)
  • 56 Views
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Open Access

Original Research

Article
Nickel nanoparticle-induced dose-dependent cyto-genotoxicity in human breast carcinoma MCF-7 cells
Maqusood Ahamed & Hisham A Alhadlaq
Pages: 269-280
Published online: 14 Feb 2014
AbstractforNickel nanoparticle-induced dose-dependent cyto-genotoxicity in human breast carcinoma MCF-7 cells | Full Text | References | PDF (1.6 MB)
  • 119 Views
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Open Access
Article
The value of radiotherapy in breast cancer patients with isolated ipsilateral supraclavicular lymph node metastasis without distant metastases at diagnosis: a retrospective analysis of Chinese patients
San-Gang Wu, Jia-Yuan Sun, Juan Zhou, Feng-Yan Li, Qin Lin, Huan-Xin Lin & Zhen-Yu He
Pages: 281-288
Published online: 15 Feb 2014
AbstractforThe value of radiotherapy in breast cancer patients with isolated ipsilateral supraclavicular lymph node metastasis without distant metastases at diagnosis: a retrospective analysis of Chinese patients | Full Text | References | PDF (294.6 KB)
  • 62 Views
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Open Access

Case Report

Case Report
Axitinib for preoperative downstaging of renal cell carcinoma with sarcomatoid differentiation and direct invasion of the duodenum and inferior vena cava: a case report
Hideo Yuki, Takao Kamai, Keiichi Kubota, Hideyuki Abe, Daisaku Nishihara, Tomoya Mizuno, Akinori Masuda, Hironori Betsunoh, Masahiro Yashi, Yoshitatsu Fukabori & Ken-Ichiro Yoshida
Pages: 289-295
Published online: 02 Dec 2022
AbstractforAxitinib for preoperative downstaging of renal cell carcinoma with sarcomatoid differentiation and direct invasion of the duodenum and inferior vena cava: a case report | Full Text | References | PDF (2.4 MB)
  • 63 Views
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Original Research

Article
Prognostic significance of the combined expression of neutral endopeptidase and dipeptidyl peptidase IV in intrahepatic cholangiocarcinoma patients after surgery resection
Jianyong Zhu, XiaoDong Guo, Baoan Qiu, Zhiyan Li, Nianxin Xia, Yingxiang Yang & Peng Liu
Pages: 297-304
Published online: 02 Dec 2022
AbstractforPrognostic significance of the combined expression of neutral endopeptidase and dipeptidyl peptidase IV in intrahepatic cholangiocarcinoma patients after surgery resection | Full Text | References | PDF (1.4 MB)
  • 55 Views
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Open Access
Article
Synergism from the combination of ulinastatin and curcumin offers greater inhibition against colorectal cancer liver metastases via modulating matrix metalloproteinase-9 and E-cadherin expression
Fei Shen, Wen-Song Cai, Jiang-Lin Li, Zhe Feng, Qi-cai Liu, Huan-qing Xiao, Jie Cao & Bo Xu
Pages: 305-314
Published online: 02 Dec 2022
AbstractforSynergism from the combination of ulinastatin and curcumin offers greater inhibition against colorectal cancer liver metastases via modulating matrix metalloproteinase-9 and E-cadherin expression | Full Text | References | PDF (3.1 MB)
  • 74 Views
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Review

Review Article
Recent advances in the ARID family: focusing on roles in human cancer
Chen Lin, Wei Song, Xinyu Bi, Jianjun Zhao, Zhen Huang, Zhiyu Li, Jianguo Zhou, Jianqiang Cai & Hong Zhao
Pages: 315-324
Published online: 02 Dec 2022
AbstractforRecent advances in the ARID family: focusing on roles in human cancer | Full Text | References | PDF (549.3 KB)
  • 161 Views
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Original Research

Article
miR-7 inhibits colorectal cancer cell proliferation and induces apoptosis by targeting XRCC2
Kaiwu Xu, Zhihui Chen, Changjiang Qin & Xinming Song
Pages: 325-332
Published online: 02 Dec 2022
AbstractformiR-7 inhibits colorectal cancer cell proliferation and induces apoptosis by targeting XRCC2 | Full Text | References | PDF (998.8 KB)
  • 88 Views
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Review

Review Article
Isotype-specific inhibition of the phosphatidylinositol-3-kinase pathway in hematologic malignancies
Jorge J Castillo, Meera Iyengar, Benjamin Kuritzky & Kenneth D Bishop
Pages: 333-342
Published online: 02 Dec 2022
AbstractforIsotype-specific inhibition of the phosphatidylinositol-3-kinase pathway in hematologic malignancies | Full Text | References | PDF (614.4 KB)
  • 67 Views
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Open Access

Original Research

Article
ABCC4 is required for cell proliferation and tumorigenesis in non-small cell lung cancer
Xiaoting Zhao, Yinan Guo, Wentao Yue, Lina Zhang, Meng Gu & Yue Wang
Pages: 343-351
Published online: 02 Dec 2022
AbstractforABCC4 is required for cell proliferation and tumorigenesis in non-small cell lung cancer | Full Text | References | PDF (816.4 KB)
  • 121 Views
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Open Access
Article
Cyclooxygenase-2 inhibitor is a robust enhancer of anticancer agents against hepatocellular carcinoma multicellular spheroids
Jie Cui, Ya-Huan Guo, Hong-Yi Zhang, Li-Li Jiang, Jie-Qun Ma, Wen-Juan Wang, Min-Cong Wang, Cheng-Cheng Yang, Ke-Jun Nan & Li-Ping Song
Pages: 353-363
Published online: 02 Dec 2022
AbstractforCyclooxygenase-2 inhibitor is a robust enhancer of anticancer agents against hepatocellular carcinoma multicellular spheroids | Full Text | References | PDF (2.9 MB)
  • 59 Views
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Open Access

Research Article

Article
Clinical impact of targeted therapies in patients with metastatic clear-cell renal cell carcinoma
Virginie Nerich, Marion Hugues, Marie Justine Paillard, Laëtitia Borowski, Thierry Nai, Ulrich Stein, Thierry Nguyen Tan Hon, Philippe Montcuquet, Tristan Maurina, Guillaume Mouillet, François Kleinclauss, Xavier Pivot, Samuel Limat & Antoine Thiery-Vuillemin
Pages: 365-374
Published online: 02 Dec 2022
AbstractforClinical impact of targeted therapies in patients with metastatic clear-cell renal cell carcinoma | Full Text | References | PDF (629.5 KB)
  • 81 Views
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Open Access

Review Article

Review Article
Development of anaplastic lymphoma kinase (ALK) inhibitors and molecular diagnosis in ALK rearrangement-positive lung cancer
Eiji Iwama, Isamu Okamoto, Taishi Harada, Koichi Takayama & Yoichi Nakanishi
Pages: 375-385
Published online: 02 Dec 2022
AbstractforDevelopment of anaplastic lymphoma kinase (ALK) inhibitors and molecular diagnosis in ALK rearrangement-positive lung cancer | Full Text | References | PDF (445.6 KB)
  • 81 Views
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Open Access
Review Article
The predictive role of pretreatment epidermal growth factor receptor T790M mutation on the progression-free survival of tyrosine-kinase inhibitor-treated non-small cell lung cancer patients: a meta-analysis
Ding Ding, Yongfeng Yu, Ziming Li, Xiaomin Niu & Shun Lu
Pages: 387-393
Published online: 02 Dec 2022
AbstractforThe predictive role of pretreatment epidermal growth factor receptor T790M mutation on the progression-free survival of tyrosine-kinase inhibitor-treated non-small cell lung cancer patients: a meta-analysis | Full Text | References | PDF (295.5 KB)
  • 65 Views
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Open Access
Review Article
Clinical efficacy and safety of imatinib in the management of Ph+ chronic myeloid or acute lymphoblastic leukemia in Chinese patients
Yu Zhu & Si-Xuan Qian
Pages: 395-404
Published online: 02 Dec 2022
AbstractforClinical efficacy and safety of imatinib in the management of Ph+ chronic myeloid or acute lymphoblastic leukemia in Chinese patients | Full Text | References | PDF (400.8 KB)
  • 78 Views
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Open Access

Original Research

Article
Clinical effectiveness, toxicity, and failure patterns of helical tomotherapy for postoperative oral cavity cancer patients
Chen-Hsi Hsieh, Pei-Wei Shueng, Li-Ying Wang, Li-Jen Liao, Yu-Chin Lin, Ying-Shiung Kuo, Wu-Chia Lo, Chien-Fu Tseng, Hui-Ju Tien, Hsiu-Ling Chou, Yen-Ping Hsieh, Le-Jung Wu & Yu-Jen Chen
Pages: 405-414
Published online: 02 Dec 2022
AbstractforClinical effectiveness, toxicity, and failure patterns of helical tomotherapy for postoperative oral cavity cancer patients | Full Text | References | PDF (995.8 KB)
  • 76 Views
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Open Access
Article
A rehabilitation program for lung cancer patients during postthoracotomy chemotherapy
Amy J Hoffman, Ruth Ann Brintnall, Alexander von Eye, Lee W Jones, Gordon Alderink, Lawrence H Patzelt & Jean K Brown
Pages: 415-423
Published online: 02 Dec 2022
AbstractforA rehabilitation program for lung cancer patients during postthoracotomy chemotherapy | Full Text | References | PDF (431.8 KB)
  • 129 Views
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Open Access
Article
Additive effect by combination of Akt inhibitor, MK-2206, and PDGFR inhibitor, tyrphostin AG 1296, in suppressing anaplastic thyroid carcinoma cell viability and motility
Huan-yong Che, Hang-yuan Guo, Xu-wei Si, Qiao-ying You & Wei-ying Lou
Pages: 425-432
Published online: 02 Dec 2022
AbstractforAdditive effect by combination of Akt inhibitor, MK-2206, and PDGFR inhibitor, tyrphostin AG 1296, in suppressing anaplastic thyroid carcinoma cell viability and motility | Full Text | References | PDF (1.5 MB)
  • 68 Views
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Open Access

Letter

Letter
Is combination of neutrophil to lymphocyte ratio and platelet lymphocyte ratio a useful predictor of postoperative survival in patients with esophageal squamous cell carcinoma?
Alpaslan Tanoglu, Ergenekon Karagoz, Nurettin Yiyit & Ufuk Berber
Pages: 433-434
Published online: 02 Dec 2022
CitationforIs combination of neutrophil to lymphocyte ratio and platelet lymphocyte ratio a useful predictor of postoperative survival in patients with esophageal squamous cell carcinoma? | Full Text | References | PDF (118.5 KB)
  • 55 Views
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Case Report

Case Report
Gastrointestinal tract metastasis from tubulolobular carcinoma of the breast: a case report and review of the literature
Guixin Wang, Tingjiang Wang, Jian Jiang, Luyao Zhou & Haidong Zhao
Pages: 435-440
Published online: 02 Dec 2022
AbstractforGastrointestinal tract metastasis from tubulolobular carcinoma of the breast: a case report and review of the literature | Full Text | References | PDF (1.4 MB)
  • 59 Views
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Original Research

Article
Cancer cell-oriented migration of mesenchymal stem cells engineered with an anticancer gene (PTEN): an imaging demonstration
Zhuo-Shun Yang, Xiang-Jun Tang, Xing-Rong Guo, Dan-Dan Zou, Xu-Yong Sun, Jing-Bo Feng, Jie Luo, Long-Jun Dai & Garth L Warnock
Pages: 441-446
Published online: 02 Dec 2022
AbstractforCancer cell-oriented migration of mesenchymal stem cells engineered with an anticancer gene (PTEN): an imaging demonstration | Full Text | References | PDF (1.1 MB)
  • 81 Views
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Open Access

Review

Review Article
Clusterin: a key player in cancer chemoresistance and its inhibition
Tomas Koltai
Pages: 447-456
Published online: 02 Dec 2022
AbstractforClusterin: a key player in cancer chemoresistance and its inhibition | Full Text | References | PDF (378 KB)
  • 168 Views
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Original Research

Article
Oncogene mutational profile in nasopharyngeal carcinoma
Zi-Chen Zhang, Sha Fu, Fang Wang, Hai-Yun Wang, Yi-Xin Zeng & Jian-Yong Shao
Pages: 457-467
Published online: 20 Mar 2014
AbstractforOncogene mutational profile in nasopharyngeal carcinoma | Full Text | References | PDF (855.9 KB)
  • 84 Views
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Open Access
Article
Retreatment with bevacizumab in patients with gynecologic malignancy is associated with clinical response and does not increase morbidity
Robin A Laskey, Scott D Richard, Ashlee L Smith, Jeff F Lin, Tiffany L Beck, Jamie L Lesnock, Joseph L Kelley 3rd, Alexander B Olawaiye, Paniti Sukumvanich & Thomas C Krivak
Pages: 469-476
Published online: 02 Dec 2022
AbstractforRetreatment with bevacizumab in patients with gynecologic malignancy is associated with clinical response and does not increase morbidity | Full Text | References | PDF (358.1 KB)
  • 72 Views
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Open Access
Article
Downregulation of CD99 and upregulation of human leukocyte antigen class II promote tumor aggravation and poor survival in patients with osteosarcomas
Quan Zhou, Jin Xu, Jiali Zhao, Shaoxian Zhang & Wei Pan
Pages: 477-484
Published online: 24 Mar 2014
AbstractforDownregulation of CD99 and upregulation of human leukocyte antigen class II promote tumor aggravation and poor survival in patients with osteosarcomas | Full Text | References | PDF (519.5 KB)
  • 61 Views
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Open Access
Article
Fractionated stereotactic radiosurgery with concurrent temozolomide chemotherapy for locally recurrent glioblastoma multiforme: a prospective cohort study
Jeffrey Noah Greenspoon, Waseem Sharieff, Holger Hirte, Andrew Overholt, Rocco Devillers, Thorsteinn Gunnarsson & Anthony Whitton
Pages: 485-490
Published online: 24 Mar 2014
AbstractforFractionated stereotactic radiosurgery with concurrent temozolomide chemotherapy for locally recurrent glioblastoma multiforme: a prospective cohort study | Full Text | References | PDF (315.1 KB)
  • 98 Views
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Review

Review Article
Potential of antibody–drug conjugates and novel therapeutics in breast cancer management
Georgios D Lianos, Konstantinos Vlachos, Odysseas Zoras, Christos Katsios, William C Cho & Dimitrios H Roukos
Pages: 491-500
Published online: 24 Mar 2014
AbstractforPotential of antibody–drug conjugates and novel therapeutics in breast cancer management | Full Text | References | PDF (250.2 KB)
  • 105 Views
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Open Access
Review Article
Role of capecitabine in treating metastatic colorectal cancer in Chinese patients
Feng Wang, Feng-Hua Wang, Long Bai & Rui-Hua Xu
Pages: 501-511
Published online: 02 Apr 2014
AbstractforRole of capecitabine in treating metastatic colorectal cancer in Chinese patients | Full Text | References | PDF (504 KB)
  • 65 Views
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Original Research

Article
Primary concomitant EGFR T790M mutation predicted worse prognosis in non-small cell lung cancer patients
Hang Li, Haichuan Hu, Rui Wang, Yunjian Pan, Lei Wang, Yuan Li, Yang Zhang, Ting Ye, Yiliang Zhang, Bin Li, Lei Shen, Yihua Sun & Haiquan Chen
Pages: 513-524
Published online: 03 Apr 2014
AbstractforPrimary concomitant EGFR T790M mutation predicted worse prognosis in non-small cell lung cancer patients | Full Text | References | PDF (792 KB)
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Article
Micro-ribonucleic acid expression profiling and bioinformatic target gene analyses in laryngeal carcinoma
Zhong-Ming Lu, Ye-Feng Lin, Li Jiang, Liang-Si Chen, Xiao-Ning Luo, Xin-Han Song, Shao-Hua Chen & Si-Yi Zhang
Pages: 525-533
Published online: 05 Apr 2014
AbstractforMicro-ribonucleic acid expression profiling and bioinformatic target gene analyses in laryngeal carcinoma | Full Text | References | PDF (1.4 MB)
  • 88 Views
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Article
Characterization of a fusion protein of RGD4C and the β-lactamase variant for antibody-directed enzyme prodrug therapy
Xiaoliang Zhou, Hao Wang, Peiji Shi & Ai-min Meng
Pages: 535-541
Published online: 10 Apr 2014
AbstractforCharacterization of a fusion protein of RGD4C and the β-lactamase variant for antibody-directed enzyme prodrug therapy | Full Text | References | PDF (851.2 KB)
  • 64 Views
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Article
PIK3CA mutations define favorable prognostic biomarkers in operable breast cancer: a systematic review and meta-analysis
Yi-Rong Liu, Wen-Jia Zuo, Ke-Da Yu & Zhi-Ming Shao
Pages: 543-552
Published online: 10 Apr 2014
AbstractforPIK3CA mutations define favorable prognostic biomarkers in operable breast cancer: a systematic review and meta-analysis | Full Text | References | PDF (372.4 KB)
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Article
Hypofractionated helical tomotherapy (75 Gy at 2.5 Gy per fraction) for localized prostate cancer: long-term analysis of gastrointestinal and genitourinary toxicity
Moonkyoo Kong, Seong Eon Hong & Sung-Goo Chang
Pages: 553-566
Published online: 10 Apr 2014
AbstractforHypofractionated helical tomotherapy (75 Gy at 2.5 Gy per fraction) for localized prostate cancer: long-term analysis of gastrointestinal and genitourinary toxicity | Full Text | References | PDF (458.5 KB)
  • 47 Views
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Article
Protein expression of programmed death 1 ligand 1 and ligand 2 independently predict poor prognosis in surgically resected lung adenocarcinoma
Yang Zhang, Lei Wang, Yuan Li, Yunjian Pan, Rui Wang, Haichuan Hu, Hang Li, Xiaoyang Luo, Ting Ye, Yihua Sun & Haiquan Chen
Pages: 567-573
Published online: 12 Apr 2014
AbstractforProtein expression of programmed death 1 ligand 1 and ligand 2 independently predict poor prognosis in surgically resected lung adenocarcinoma | Full Text | References | PDF (2.1 MB)
  • 162 Views
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Review

Review Article
Microtubule-targeting agents in oncology and therapeutic potential in hepatocellular carcinoma
Herbert H Loong & Winnie Yeo
Pages: 575-585
Published online: 16 Apr 2014
AbstractforMicrotubule-targeting agents in oncology and therapeutic potential in hepatocellular carcinoma | Full Text | References | PDF (282.8 KB)
  • 129 Views
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Original Research

Article
MiR-519d represses ovarian cancer cell proliferation and enhances cisplatin-mediated cytotoxicity in vitro by targeting XIAP
Yingxin Pang, Hongluan Mao, Liang Shen, Zhe Zhao, Ruihan Liu & Peishu Liu
Pages: 587-597
Published online: 23 Apr 2014
AbstractforMiR-519d represses ovarian cancer cell proliferation and enhances cisplatin-mediated cytotoxicity in vitro by targeting XIAP | Full Text | References | PDF (2.3 MB)
  • 64 Views
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Review

Review Article
Neuropathic cancer pain: What we are dealing with? How to manage it?
Ece Esin & Suayib Yalcin
Pages: 599-618
Published online: 17 Apr 2014
AbstractforNeuropathic cancer pain: What we are dealing with? How to manage it? | Full Text | References | PDF (385.7 KB)
  • 323 Views
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Review Article
Clinical utility of circulating tumor cell counting through CellSearch®: the dilemma of a concept suspended in Limbo
Cristina Raimondi, Angela Gradilone, Giuseppe Naso, Enrico Cortesi & Paola Gazzaniga
Pages: 619-625
Published online: 17 Apr 2014
AbstractforClinical utility of circulating tumor cell counting through CellSearch®: the dilemma of a concept suspended in Limbo | Full Text | References | PDF (194.1 KB)
  • 93 Views
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Original Research

Article
Health behaviors and quality of life in Chinese survivors of cervical cancer: a retrospective study
Shu-xia Nie & Chuan-qiang Gao
Pages: 627-632
Published online: 23 Apr 2014
AbstractforHealth behaviors and quality of life in Chinese survivors of cervical cancer: a retrospective study | Full Text | References | PDF (451.4 KB)
  • 81 Views
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Case Report

Case Report
Two thymus-related autoimmune disorders: a case report and review of the literature
Hanifeh Mirtavoos-Mahyari, Adnan Khosravi, Zahra Esfahani-Monfared & Mohammad Behgam Shadmehr
Pages: 633-636
Published online: 02 Dec 2022
AbstractforTwo thymus-related autoimmune disorders: a case report and review of the literature | Full Text | References | PDF (722.9 KB)
  • 81 Views
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Original Research

Article
Involvement of c-KIT mutation in the development of gastrointestinal stromal tumors through proliferation promotion and apoptosis inhibition
Ying-Yu Ma, Sheng Yu, Xu-Jun He, Yuan Xu, Fang Wu, Ying-Jie Xia, Kun Guo, Hui-Ju Wang, Zai-Yuan Ye, Wei Zhang & Hou-Quan Tao
Pages: 637-643
Published online: 02 May 2014
AbstractforInvolvement of c-KIT mutation in the development of gastrointestinal stromal tumors through proliferation promotion and apoptosis inhibition | Full Text | References | PDF (2.1 MB)
  • 65 Views
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Article
Stage-dependent prognostic impact of molecular signatures in clear cell renal cell carcinoma
Thomas Weber, Matthias Meinhardt, Stefan Zastrow, Andreas Wienke, Kati Erdmann, Jörg Hofmann, Susanne Fuessel & Manfred P Wirth
Pages: 645-654
Published online: 02 May 2014
AbstractforStage-dependent prognostic impact of molecular signatures in clear cell renal cell carcinoma | Full Text | References | PDF (1.6 MB)
  • 66 Views
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Article
Exome sequencing reveals a potential mutational trajectory and treatments for a specific pancreatic cancer patient
James Cotterell
Pages: 655-662
Published online: 03 May 2014
AbstractforExome sequencing reveals a potential mutational trajectory and treatments for a specific pancreatic cancer patient | Full Text | References | PDF (1,001.6 KB)
  • 67 Views
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Case Report

Case Report
Primary small-cell neuroendocrine carcinoma of the male breast: a rare case report with review of the literature
Jian Jiang, Guixin Wang, Li Lv, Caigang Liu, Xi Liang & Haidong Zhao
Pages: 663-666
Published online: 06 May 2014
AbstractforPrimary small-cell neuroendocrine carcinoma of the male breast: a rare case report with review of the literature | Full Text | References | PDF (937.6 KB)
  • 61 Views
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Original Research

Article
Transcriptional targeting of sphingosine-1-phosphate receptor S1P2 by epigallocatechin-3-gallate prevents sphingosine-1-phosphate-mediated signaling in macrophage-differentiated HL-60 promyelomonocytic leukemia cells
Rima Chokor, Sylvie Lamy & Borhane Annabi
Pages: 667-677
Published online: 07 May 2014
AbstractforTranscriptional targeting of sphingosine-1-phosphate receptor S1P2 by epigallocatechin-3-gallate prevents sphingosine-1-phosphate-mediated signaling in macrophage-differentiated HL-60 promyelomonocytic leukemia cells | Full Text | References | PDF (1.5 MB)
  • 74 Views
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Case Report

Case Report
Renal malignant solitary fibrous tumor with single lymph node involvement: report of unusual metastasis and review of the literature
Ettore Mearini, Giovanni Cochetti, Francesco Barillaro, Sonia Fatigoni & Fausto Roila
Pages: 679-685
Published online: 08 May 2014
AbstractforRenal malignant solitary fibrous tumor with single lymph node involvement: report of unusual metastasis and review of the literature | Full Text | References | PDF (3.3 MB)
  • 62 Views
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Original Research

Article
Quality of life assessment in advanced cancer patients treated at home, an inpatient unit, and a day care center
Wojciech Leppert, Mikolaj Majkowicz, Maria Forycka, Eleonora Mess & Agata Zdun-Ryzewska
Pages: 687-695
Published online: 02 Dec 2022
AbstractforQuality of life assessment in advanced cancer patients treated at home, an inpatient unit, and a day care center | Full Text | References | PDF (296.4 KB)
  • 89 Views
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Case Report

Case Report
Antitumor activity of sorafenib and imatinib in a patient with thymic carcinoma harboring c-KIT exon 13 missense mutation K642E
Chiara Catania, Fabio Conforti, Gianluca Spitaleri, Massimo Barberis, Lorenzo Preda, Cristina Noberasco, Chiara Lazzari, Francesca Toffalorio, Filippo de Marinis, Michela Manzotti & Tommaso Martino De Pas
Pages: 697-702
Published online: 08 May 2014
AbstractforAntitumor activity of sorafenib and imatinib in a patient with thymic carcinoma harboring c-KIT exon 13 missense mutation K642E | Full Text | References | PDF (2.7 MB)
  • 60 Views
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Original Research

Article
IL-17A (-197G/A) and IL-17F (7488T/C) gene polymorphisms and cancer risk in Asian population: a meta-analysis
Wei Dai, Qing Zhou, Xuexin Tan & Changfu Sun
Pages: 703-711
Published online: 13 May 2014
AbstractforIL-17A (-197G/A) and IL-17F (7488T/C) gene polymorphisms and cancer risk in Asian population: a meta-analysis | Full Text | References | PDF (455 KB)
  • 59 Views
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Expert Opinion

Editorial
Considering the role of radiation therapy for gastrointestinal stromal tumor
Kimberly S Corbin, Hedy L Kindler & Stanley L Liauw
Pages: 713-718
Published online: 02 Dec 2022
AbstractforConsidering the role of radiation therapy for gastrointestinal stromal tumor | Full Text | References | PDF (181 KB)
  • 78 Views
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Review

Review Article
Clinical response to sunitinib as a multitargeted tyrosine-kinase inhibitor (TKI) in solid cancers: a review of clinical trials
Sungkyoung Kim, Wenping Ding, Lian Zhang, Wei Tian & Siyu Chen
Pages: 719-728
Published online: 12 May 2014
AbstractforClinical response to sunitinib as a multitargeted tyrosine-kinase inhibitor (TKI) in solid cancers: a review of clinical trials | Full Text | References | PDF (303.6 KB)
  • 121 Views
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Original Research

Article
Investigation and analysis of oncologists’ knowledge of morphine usage in cancer pain treatment
Weiran Liu, Shumin Xie, Lin Yue, Jiahao Liu, Stephanie Mu-Lian Woo, Weilin Liu, Adam R Miller, Jing Zhang, Lijun Huang & Lei Zhang
Pages: 729-737
Published online: 02 Dec 2022
AbstractforInvestigation and analysis of oncologists’ knowledge of morphine usage in cancer pain treatment | Full Text | References | PDF (234.7 KB)
  • 109 Views
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Article
Prognostic value of pretreatment serum levels of lactate dehydrogenase in nonmetastatic nasopharyngeal carcinoma: single-site analysis of 601 patients in a highly endemic area
Zhengbo Wei, Xianjie Zeng, Jian Xu, Xuwei Duan & Ying Xie
Pages: 739-749
Published online: 02 Dec 2022
AbstractforPrognostic value of pretreatment serum levels of lactate dehydrogenase in nonmetastatic nasopharyngeal carcinoma: single-site analysis of 601 patients in a highly endemic area | Full Text | References | PDF (319.6 KB)
  • 59 Views
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Review

Review Article
Clinical potential of bevacizumab in the treatment of metastatic and locally advanced cervical cancer: current evidence
Matthew W Jackson, Chad G Rusthoven, Christine M Fisher & Tracey E Schefter
Pages: 751-759
Published online: 16 May 2014
AbstractforClinical potential of bevacizumab in the treatment of metastatic and locally advanced cervical cancer: current evidence | Full Text | References | PDF (235.9 KB)
  • 83 Views
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Review Article
Treating advanced non-small-cell lung cancer in Chinese patients: focus on icotinib
Jun-Li Liang, Xiao-Cang Ren & Qiang Lin
Pages: 761-770
Published online: 16 May 2014
AbstractforTreating advanced non-small-cell lung cancer in Chinese patients: focus on icotinib | Full Text | References | PDF (279.4 KB)
  • 54 Views
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Original Research

Article
Manumycin induces apoptosis in prostate cancer cells
Jing-Gao Li, Miao-Rong She, Ci-Yong Lu, Shan-Shan Wei, Ping-Fang Xia, Ze-Sheng Lu & Qi Peng
Pages: 771-777
Published online: 22 May 2014
AbstractforManumycin induces apoptosis in prostate cancer cells | Full Text | References | PDF (1.1 MB)
  • 68 Views
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Article
Preparation and functional studies of hydroxyethyl chitosan nanoparticles loaded with anti-human death receptor 5 single-chain antibody
Jingjing Yang, Xiaoping Huang, Fanghong Luo, Xiaofeng Cheng, Lianna Cheng, Bin Liu, Lihong Chen, Ruyi Hu, Chunyan Shi, Guohong Zhuang & Ping Yin
Pages: 779-787
Published online: 02 Dec 2022
AbstractforPreparation and functional studies of hydroxyethyl chitosan nanoparticles loaded with anti-human death receptor 5 single-chain antibody | Full Text | References | PDF (2.5 MB)
  • 67 Views
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Article
Positron emission tomographic monitoring of dual phosphatidylinositol-3-kinase and mTOR inhibition in anaplastic large cell lymphoma
Nicolas Graf, Zhoulei Li, Ken Herrmann, Daniel Weh, Michaela Aichler, Jolanta Slawska, Axel Walch, Christian Peschel, Markus Schwaiger, Andreas K Buck, Tobias Dechow & Ulrich Keller
Pages: 789-798
Published online: 02 Dec 2022
AbstractforPositron emission tomographic monitoring of dual phosphatidylinositol-3-kinase and mTOR inhibition in anaplastic large cell lymphoma | Full Text | References | PDF (1.1 MB)
  • 62 Views
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Article
Prior EGFR tyrosine-kinase inhibitor therapy did not influence the efficacy of subsequent pemetrexed plus platinum in advanced chemonaïve patients with EGFR-mutant lung adenocarcinoma
Jeng-Sen Tseng, Tsung-Ying Yang, Kun-Chieh Chen, Kuo-Hsuan Hsu, Chong-Jen Yu, Wei-Yu Liao, Chi-Ren Tsai, Meen-Hsin Tsai, Sung-Liang Yu, Kang-Yi Su, Jeremy JW Chen, Hsuan-Yu Chen & Gee-Chen Chang
Pages: 799-805
Published online: 02 Dec 2022
AbstractforPrior EGFR tyrosine-kinase inhibitor therapy did not influence the efficacy of subsequent pemetrexed plus platinum in advanced chemonaïve patients with EGFR-mutant lung adenocarcinoma | Full Text | References | PDF (331.2 KB)
  • 55 Views
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Article
Preliminary analysis of the risk factors for radiation pneumonitis in patients with non-small-cell lung cancer treated with concurrent erlotinib and thoracic radiotherapy
Hongqing Zhuang, Zhiyong Yuan, Jun Wang, Qingsong Pang, Lujun Zhao & Ping Wang
Pages: 807-813
Published online: 24 May 2014
AbstractforPreliminary analysis of the risk factors for radiation pneumonitis in patients with non-small-cell lung cancer treated with concurrent erlotinib and thoracic radiotherapy | Full Text | References | PDF (296.9 KB)
  • 61 Views
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Article
Prevalence and relationship between major depressive disorder and lung cancer: a cross-sectional study
Benchalak Maneeton, Narong Maneeton, Jirayu Reungyos, Suthi Intaprasert, Samornsri Leelarphat & Sumitra Thongprasert
Pages: 815-821
Published online: 27 May 2014
AbstractforPrevalence and relationship between major depressive disorder and lung cancer: a cross-sectional study | Full Text | References | PDF (287.9 KB)
  • 213 Views
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Case Series

Comprehensive clinical and pathological analysis of aggressive renal epithelioid angiomyolipoma: report of three cases
Jindan Luo, Ben Liu, Yanli Wang, Jun Li, Ping Wang, Jun Chen & Chaojun Wang
Pages: 823-827
Published online: 27 May 2014
AbstractforComprehensive clinical and pathological analysis of aggressive renal epithelioid angiomyolipoma: report of three cases | Full Text | References | PDF (2 MB)
  • 66 Views
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Case Report

Case Report
Serial changes of clinical parameters in a patient with advanced hepatocellular carcinoma with portal vein thrombosis achieving complete response after treatment with sorafenib
Kwong-Ming Kee, Chao-Hung Hung, Jing-Houng Wang & Sheng-Nan Lu
Pages: 829-834
Published online: 02 Dec 2022
AbstractforSerial changes of clinical parameters in a patient with advanced hepatocellular carcinoma with portal vein thrombosis achieving complete response after treatment with sorafenib | Full Text | References | PDF (1.4 MB)
  • 48 Views
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Review

Review Article
Cerium oxide nanoparticles in cancer
Ying Gao, Kan Chen, Jin-lu Ma & Fei Gao
Pages: 835-840
Published online: 27 May 2014
AbstractforCerium oxide nanoparticles in cancer | Full Text | References | PDF (187.8 KB)
  • 875 Views
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Review Article
Critical appraisal of the role of gefitinib in the management of locally advanced or metastatic non-small cell lung cancer
Ying Yuan, Xiao-Fen Li, Jia-Qi Chen, Cai-Xia Dong, Shan-Shan Weng & Jian-Jin Huang
Pages: 841-852
Published online: 28 May 2014
AbstractforCritical appraisal of the role of gefitinib in the management of locally advanced or metastatic non-small cell lung cancer | Full Text | References | PDF (740.8 KB)
  • 76 Views
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Original Research

Article
Clinical significance of promoter region hypermethylation of microRNA-148a in gastrointestinal cancers
Jingxu Sun, Yongxi Song, Zhenning Wang, Guoli Wang, Peng Gao, Xiaowan Chen, Zhaohua Gao & Huimian Xu
Pages: 853-863
Published online: 28 May 2014
AbstractforClinical significance of promoter region hypermethylation of microRNA-148a in gastrointestinal cancers | Full Text | References | PDF (1.4 MB)
  • 66 Views
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Review

Review Article
Pixantrone for the treatment of adult patients with relapsed or refractory aggressive non-Hodgkin B-cell lymphomas
Stefano Volpetti, Francesco Zaja & Renato Fanin
Pages: 865-872
Published online: 29 May 2014
AbstractforPixantrone for the treatment of adult patients with relapsed or refractory aggressive non-Hodgkin B-cell lymphomas | Full Text | References | PDF (242 KB)
  • 65 Views
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Original Research

Article
Cyclic adenosine monophosphate-responsive element-binding protein activation predicts an unfavorable prognosis in patients with hepatocellular carcinoma
Lingxiang Yu, Peirui Zhang, Ruizhao Qi, Zhiwei Li & Shaogeng Zhang
Pages: 873-879
Published online: 29 May 2014
AbstractforCyclic adenosine monophosphate-responsive element-binding protein activation predicts an unfavorable prognosis in patients with hepatocellular carcinoma | Full Text | References | PDF (1.6 MB)
  • 61 Views
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Short Report

Brief Report
Overexpression of Abl2 predicts poor prognosis in hepatocellular carcinomas and is associated with cancer cell migration and invasion
Quan-tai Xing, Chun-mei Qu & Gang Wang
Pages: 881-885
Published online: 30 May 2014
AbstractforOverexpression of Abl2 predicts poor prognosis in hepatocellular carcinomas and is associated with cancer cell migration and invasion | Full Text | References | PDF (2.3 MB)
  • 79 Views
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Original Research

Article
High expression of 23 kDa protein of augmenter of liver regeneration (ALR) in human hepatocellular carcinoma
Hai-Ying Yu, Man-Hua Zhu, Dai-Rong Xiang, Jun Li & Ji-Fang Sheng
Pages: 887-893
Published online: 02 Jun 2014
AbstractforHigh expression of 23 kDa protein of augmenter of liver regeneration (ALR) in human hepatocellular carcinoma | Full Text | References | PDF (1.4 MB)
  • 62 Views
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Article
miR-544a promotes the invasion of lung cancer cells by targeting cadherina 1 in vitro
Xiaomei Mo, Fenghua Zhang, Hui Liang, Ming Liu, Huahui Li & Haiping Xia
Pages: 895-900
Published online: 04 Jun 2014
AbstractformiR-544a promotes the invasion of lung cancer cells by targeting cadherina 1 in vitro | Full Text | References | PDF (916.5 KB)
  • 55 Views
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Review

Review Article
The potential clinical applications and prospects of microRNAs in lung cancer
Ying Gao, Fei Gao, Jin-lu Ma, Wen-ze Sun & Li-ping Song
Pages: 901-906
Published online: 04 Jun 2014
AbstractforThe potential clinical applications and prospects of microRNAs in lung cancer | Full Text | References | PDF (182.4 KB)
  • 74 Views
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Original Research

Article
Effect of NQO1 C609T polymorphism on prostate cancer risk: a meta-analysis
Qi Zhang, Min Zheng, Xiao-Long Qi, Feng Liu, Zu-Jie Mao & Da-Hong Zhang
Pages: 907-914
Published online: 05 Jun 2014
AbstractforEffect of NQO1 C609T polymorphism on prostate cancer risk: a meta-analysis | Full Text | References | PDF (365.9 KB)
  • 63 Views
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Article
Stereotactic body radiation therapy using the CyberKnife® system for patients with liver metastases
Zhi-Yong Yuan, Mao-Bin Meng, Chun-Lei Liu, Huan-Huan Wang, Chao Jiang, Yong-Chun Song, Hong-Qing Zhuang, Dong Yang, Jing-Sheng Wang, Wang Wei, Feng-Tong Li, Lu-Jun Zhao & Ping Wang
Pages: 915-923
Published online: 12 Jun 2014
AbstractforStereotactic body radiation therapy using the CyberKnife® system for patients with liver metastases | Full Text | References | PDF (2.1 MB)
  • 115 Views
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Review

Review Article
Critical appraisal of sorafenib in the treatment of Chinese patients with renal cell carcinoma
Ding-Wei Ye & Hai-Liang Zhang
Pages: 925-935
Published online: 06 Jun 2014
AbstractforCritical appraisal of sorafenib in the treatment of Chinese patients with renal cell carcinoma | Full Text | References | PDF (290.5 KB)
  • 60 Views
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Review Article
Critical appraisal of pemetrexed in the treatment of NSCLC and metastatic pulmonary nodules
Xin Li, Sen Wei & Jun Chen
Pages: 937-945
Published online: 06 Jun 2014
AbstractforCritical appraisal of pemetrexed in the treatment of NSCLC and metastatic pulmonary nodules | Full Text | References | PDF (268.5 KB)
  • 68 Views
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Original Research

Article
Antitumor activity of total flavonoids from Tetrastigma hemsleyanum Diels et Gilg is associated with the inhibition of regulatory T cells in mice
Zhengquan Feng, Wanrong Hao, Xiaoyang Lin, Daping Fan & Juhua Zhou
Pages: 947-956
Published online: 09 Jun 2014
AbstractforAntitumor activity of total flavonoids from Tetrastigma hemsleyanum Diels et Gilg is associated with the inhibition of regulatory T cells in mice | Full Text | References | PDF (1.5 MB)
  • 143 Views
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Article
Prognosis of patients with hepatocellular carcinoma and hypersplenism after surgery: a single-center experience from the People’s Republic of China
Cong Li, Hong Zhao, Jianjun Zhao, Zhiyu Li, Zhen Huang, Yefan Zhang, Xinyu Bi & Jianqiang Cai
Pages: 957-964
Published online: 09 Jun 2014
AbstractforPrognosis of patients with hepatocellular carcinoma and hypersplenism after surgery: a single-center experience from the People’s Republic of China | Full Text | References | PDF (430.2 KB)
  • 59 Views
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Open Access

Case Report

Case Report
Paraganglioma of the vagina: a case report and review of the literature
Tao Cai, Yucong Li, Qingming Jiang, Dong Wang & Yu Huang
Pages: 965-968
Published online: 10 Jun 2014
AbstractforParaganglioma of the vagina: a case report and review of the literature | Full Text | References | PDF (968.4 KB)
  • 65 Views
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Review

Review Article
The potential roles of hepatocyte growth factor (HGF)-MET pathway inhibitors in cancer treatment
Rahul A Parikh, Peng Wang, Jan H Beumer, Edward Chu & Leonard J Appleman
Pages: 969-983
Published online: 11 Jun 2014
AbstractforThe potential roles of hepatocyte growth factor (HGF)-MET pathway inhibitors in cancer treatment | Full Text | References | PDF (1.2 MB)
  • 124 Views
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Original Research

Article
xCELLigence system for real-time label-free monitoring of growth and viability of cell lines from hematological malignancies
Jordi Martinez-Serra, Antonio Gutierrez, Saúl Muñoz-Capó, María Navarro-Palou, Teresa Ros, Juan Carlos Amat, Bernardo Lopez, Toni F Marcus, Laura Fueyo, Angela G Suquia, Jordi Gines, Francisco Rubio, Rafael Ramos & Joan Besalduch
Pages: 985-994
Published online: 12 Jun 2014
AbstractforxCELLigence system for real-time label-free monitoring of growth and viability of cell lines from hematological malignancies | Full Text | References | PDF (3.2 MB)
  • 299 Views
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Article
Single incision versus conventional laparoscopic resection in gastrointestinal stromal tumors: a retrospective cohort analysis at a single tertiary care center
Jing Kong, Shuo-Dong Wu, Yang Su & Ying Fan
Pages: 995-999
Published online: 02 Dec 2022
AbstractforSingle incision versus conventional laparoscopic resection in gastrointestinal stromal tumors: a retrospective cohort analysis at a single tertiary care center | Full Text | References | PDF (178 KB)
  • 55 Views
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Review

Review Article
Emerging molecular targets in oncology: clinical potential of MET/hepatocyte growth-factor inhibitors
Elizabeth C Smyth, Francesco Sclafani & David Cunningham
Pages: 1001-1014
Published online: 12 Jun 2014
AbstractforEmerging molecular targets in oncology: clinical potential of MET/hepatocyte growth-factor inhibitors | Full Text | References | PDF (314.4 KB)
  • 132 Views
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Review Article
Chemotherapy-enhanced inflammation may lead to the failure of therapy and metastasis
Dinesh Vyas, Gieric Laput & Arpitak K Vyas
Pages: 1015-1023
Published online: 12 Jun 2014
AbstractforChemotherapy-enhanced inflammation may lead to the failure of therapy and metastasis | Full Text | References | PDF (866.1 KB)
  • 270 Views
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Review Article
Bevacizumab in combination with chemotherapy in platinum-sensitive ovarian cancer
Chiara Della Pepa & Susana Banerjee
Pages: 1025-1032
Published online: 02 Dec 2022
AbstractforBevacizumab in combination with chemotherapy in platinum-sensitive ovarian cancer | Full Text | References | PDF (228.4 KB)
  • 86 Views
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Original Research

Article
Gemcitabine resistance in breast cancer cells regulated by PI3K/AKT-mediated cellular proliferation exerts negative feedback via the MEK/MAPK and mTOR pathways
Xiao Li Yang, Feng Juan Lin, Ya Jie Guo, Zhi Min Shao & Zhou Luo Ou
Pages: 1033-1042
Published online: 13 Jun 2014
AbstractforGemcitabine resistance in breast cancer cells regulated by PI3K/AKT-mediated cellular proliferation exerts negative feedback via the MEK/MAPK and mTOR pathways | Full Text | References | PDF (1.9 MB)
  • 158 Views
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Review

Review Article
Myelodysplastic disorders carrying both isolated del(5q) and JAK2V617F mutation: concise review, with focus on lenalidomide therapy
Pellegrino Musto, Vittorio Simeon, Roberto Guariglia, Gabriella Bianchino, Vitina Grieco, Filomena Nozza, Francesco La Rocca, Gioacchino Marziano, Anna Vittoria Lalinga, Emiliano Fabiani, Maria Teresa Voso, Patrizia Scaravaglio, Cristina Mecucci & Giovanni D’Arena
Pages: 1043-1050
Published online: 13 Jun 2014
AbstractforMyelodysplastic disorders carrying both isolated del(5q) and JAK2V617F mutation: concise review, with focus on lenalidomide therapy | Full Text | References | PDF (1.1 MB)
  • 79 Views
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Original Research

Article
Nimotuzumab plus chemotherapy versus chemotherapy alone in advanced non-small-cell lung cancer: a multicenter, randomized, open-label Phase II study
K Govind Babu, Kumar Prabhash, Ashok K Vaid, Bhawna Sirohi, Ravi B Diwakar, Raghunadha Rao, Madhuchanda Kar, Hemant Malhotra, Shona Nag, Chanchal Goswami, Vinod Raina & Ravi Mohan
Pages: 1051-1060
Published online: 13 Jun 2014
AbstractforNimotuzumab plus chemotherapy versus chemotherapy alone in advanced non-small-cell lung cancer: a multicenter, randomized, open-label Phase II study | Full Text | References | PDF (619.3 KB)
  • 83 Views
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Article
HCA519/TPX2: a potential T-cell tumor-associated antigen for human hepatocellular carcinoma
Ahmed M Aref, Neil T Hoa, Lisheng Ge, Anshu Agrawal, Maria Dacosta-Iyer, Nils Lambrecht, Yi Ouyang, Andrew N Cornforth & Martin R Jadus
Pages: 1061-1070
Published online: 13 Jun 2014
AbstractforHCA519/TPX2: a potential T-cell tumor-associated antigen for human hepatocellular carcinoma | Full Text | References | PDF (1.5 MB)
  • 63 Views
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Article
Pilot study of intratumoral injection of recombinant heat shock protein 70 in the treatment of malignant brain tumors in children
Maxim A Shevtsov, Alexander V Kim, Konstantin A Samochernych, Irina V Romanova, Boris A Margulis, Irina V Guzhova, Igor V Yakovenko, Alexander M Ischenko & William A Khachatryan
Pages: 1071-1081
Published online: 18 Jun 2014
AbstractforPilot study of intratumoral injection of recombinant heat shock protein 70 in the treatment of malignant brain tumors in children | Full Text | References | PDF (836 KB)
  • 81 Views
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Article
ID2 predicts poor prognosis in breast cancer, especially in triple-negative breast cancer, and inhibits E-cadherin expression
Kai Li, Ling Yao, Li Chen, Zhi-Gang Cao, San-Jian Yu, Xia-Ying Kuang, Xin Hu & Zhi-Ming Shao
Pages: 1083-1094
Published online: 02 Dec 2022
AbstractforID2 predicts poor prognosis in breast cancer, especially in triple-negative breast cancer, and inhibits E-cadherin expression | Full Text | References | PDF (2 MB)
  • 77 Views
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Review

Review Article
Potential role of daratumumab in the treatment of multiple myeloma
Yulian Khagi & Tomer M Mark
Pages: 1095-1100
Published online: 18 Jun 2014
AbstractforPotential role of daratumumab in the treatment of multiple myeloma | Full Text | References | PDF (191 KB)
  • 105 Views
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Original Research

Article
Progression-free survival as a potential surrogate for overall survival in metastatic breast cancer
Catherine Beauchemin, Dan Cooper, Marie-Ève Lapierre, Louise Yelle & Jean Lachaine
Pages: 1101-1110
Published online: 18 Jun 2014
AbstractforProgression-free survival as a potential surrogate for overall survival in metastatic breast cancer | Full Text | References | PDF (665.3 KB)
  • 98 Views
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Case Report

Case Report
Recall radiation dermatitis by sorafenib following stereotactic body radiation therapy
Chen-Hsi Hsieh, Shih-Chiang Lin, Pei-Wei Shueng & Deng-Yu Kuo
Pages: 1111-1114
Published online: 02 Dec 2022
AbstractforRecall radiation dermatitis by sorafenib following stereotactic body radiation therapy | Full Text | References | PDF (655.1 KB)
  • 71 Views
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Case Report
Neoadjuvant therapy for locally advanced melanoma: new strategies with targeted therapies
Michele La Greca, Giuseppe Grasso, Giovanna Antonelli, Alessia Erika Russo, Salvatore Bartolotta, Alessandro D’Angelo, Felice Vito Vitale & Francesco Ferraù
Pages: 1115-1121
Published online: 19 Jun 2014
AbstractforNeoadjuvant therapy for locally advanced melanoma: new strategies with targeted therapies | Full Text | References | PDF (1.2 MB)
  • 68 Views
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Case Report
Combination therapy with brentuximab vedotin and cisplatin/cytarabine in a patient with primarily refractory anaplastic lymphoma kinase positive anaplastic large cell lymphoma
Simon Heidegger, Ambros J Beer, Eva Geissinger, Andreas Rosenwald, Christian Peschel, Ingo Ringshausen & Ulrich Keller
Pages: 1123-1127
Published online: 02 Dec 2022
AbstractforCombination therapy with brentuximab vedotin and cisplatin/cytarabine in a patient with primarily refractory anaplastic lymphoma kinase positive anaplastic large cell lymphoma | Full Text | References | PDF (862.8 KB)
  • 84 Views
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Perspectives

Article
Stemness and plasticity of lung cancer cells: paving the road for better therapy
Judong Luo, Xifa Zhou & Juan Sebastian Yakisich
Pages: 1129-1134
Published online: 02 Dec 2022
AbstractforStemness and plasticity of lung cancer cells: paving the road for better therapy | Full Text | References | PDF (196.5 KB)
  • 80 Views
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Case Series

Clinical analysis of 13 males with primary choriocarcinoma and review of the literature
Fang Jiang, Yang Xiang, Feng-Zhi Feng, Tong Ren, Zhu-Mei Cui & Xi-Run Wan
Pages: 1135-1141
Published online: 20 Jun 2014
AbstractforClinical analysis of 13 males with primary choriocarcinoma and review of the literature | Full Text | References | PDF (300.7 KB)
  • 89 Views
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Original Research

Article
Integration of multidisciplinary technologies for real time target visualization and verification for radiotherapy
Wen-Chung Chang, Chin-Sheng Chen, Hung-Chi Tai, Chia-Yuan Liu & Yu-Jen Chen
Pages: 1143-1150
Published online: 23 Jun 2014
AbstractforIntegration of multidisciplinary technologies for real time target visualization and verification for radiotherapy | Full Text | References | PDF (2.9 MB)
  • 56 Views
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Review

Review Article
Mapping lymph nodes in cancer management – role of 99mTc-tilmanocept injection
Christoph Tausch, Astrid Baege & Christoph Rageth
Pages: 1151-1158
Published online: 24 Jun 2014
AbstractforMapping lymph nodes in cancer management – role of 99mTc-tilmanocept injection | Full Text | References | PDF (254.8 KB)
  • 80 Views
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Original Research

Article
Clinicopathological and biological significance of aberrant activation of glycogen synthase kinase-3 in ovarian cancer
Yunfeng Fu, Xinyu Wang, Xiaodong Cheng, Feng Ye, Xing Xie & Weiguo Lu
Pages: 1159-1168
Published online: 25 Jun 2014
AbstractforClinicopathological and biological significance of aberrant activation of glycogen synthase kinase-3 in ovarian cancer | Full Text | References | PDF (2.6 MB)
  • 67 Views
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Article
Modeling pegylated liposomal doxorubicin-induced hand-foot syndrome and intestinal mucositis in zebrafish
Yau-Hung Chen, Ya-Ting Lee, Chi-Chung Wen, Yun-Chen Chen & Yu-Jen Chen
Pages: 1169-1175
Published online: 01 Jul 2014
AbstractforModeling pegylated liposomal doxorubicin-induced hand-foot syndrome and intestinal mucositis in zebrafish | Full Text | References | PDF (2.2 MB)
  • 53 Views
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Article
A single-institution experience with bevacizumab in the treatment of metastatic colorectal cancer and in conjunction with liver resection
Pia Osterlund, Reetta Peltonen, Tuomo Alanko, Petri Bono & Helena Isoniemi
Pages: 1177-1184
Published online: 02 Dec 2022
AbstractforA single-institution experience with bevacizumab in the treatment of metastatic colorectal cancer and in conjunction with liver resection | Full Text | References | PDF (682.4 KB)
  • 55 Views
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Article
Correlation between EGFR mutation status and response to first-line platinum-based chemotherapy in patients with advanced non-small cell lung cancer
Shu Fang, Zhehai Wang, Jun Guo, Jie Liu, Changzheng Li, Lin Liu, Huan Shi, Liyan Liu, Huihui Li, Chao Xie, Xia Zhang, Wenwen Sun & Minmin Li
Pages: 1185-1193
Published online: 02 Dec 2022
AbstractforCorrelation between EGFR mutation status and response to first-line platinum-based chemotherapy in patients with advanced non-small cell lung cancer | Full Text | References | PDF (573.3 KB)
  • 81 Views
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Article
Expression profiles and initial confirmation of long noncoding RNAs in Chinese patients with pulmonary adenocarcinoma
Xin Zhao, Wen Zhu, Wangjian Zha, Feifei Chen, Zhenzhen Wu, Yanan Liu & Mao Huang
Pages: 1195-1204
Published online: 01 Jul 2014
AbstractforExpression profiles and initial confirmation of long noncoding RNAs in Chinese patients with pulmonary adenocarcinoma | Full Text | References | PDF (1.3 MB)
  • 60 Views
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Article
Histological type-specific prognostic factors of cervical small cell neuroendocrine carcinoma, adenocarcinoma, and squamous cell carcinoma
Suthida Intaraphet, Nongyao Kasatpibal, Mette Søgaard, Surapan Khunamornpong, Jayanton Patumanond, Anchalee Chandacham, Imjai Chitapanarux & Sumalee Siriaunkgul
Pages: 1205-1214
Published online: 02 Dec 2022
AbstractforHistological type-specific prognostic factors of cervical small cell neuroendocrine carcinoma, adenocarcinoma, and squamous cell carcinoma | Full Text | References | PDF (590.5 KB)
  • 72 Views
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Article
CP-673451, a platelet-derived growth-factor receptor inhibitor, suppresses lung cancer cell proliferation and migration
Yuling Xi, Ming Chen, Xinmin Liu, Zhongmin Lu, Yi Ding & Datong Li
Pages: 1215-1221
Published online: 03 Jul 2014
AbstractforCP-673451, a platelet-derived growth-factor receptor inhibitor, suppresses lung cancer cell proliferation and migration | Full Text | References | PDF (2.1 MB)
  • 93 Views
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Review

Review Article
Targeted drug delivery via folate receptors in recurrent ovarian cancer: a review
Claudia Marchetti, Innocenza Palaia, Margherita Giorgini, Caterina De Medici, Roberta Iadarola, Laura Vertechy, Lavinia Domenici, Violante Di Donato, Federica Tomao, Ludovico Muzii & Pierluigi Benedetti Panici
Pages: 1223-1236
Published online: 10 Jul 2014
AbstractforTargeted drug delivery via folate receptors in recurrent ovarian cancer: a review | Full Text | References | PDF (817.5 KB)
  • 313 Views
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Original Research

Article
Clinical significance and association of RUNX3 hypermethylation frequency with colorectal cancer: a meta-analysis
Wei-Ping Mu, Jian Wang, Qiong Niu, Ning Shi & Hai-Feng Lian
Pages: 1237-1245
Published online: 10 Jul 2014
AbstractforClinical significance and association of RUNX3 hypermethylation frequency with colorectal cancer: a meta-analysis | Full Text | References | PDF (420.9 KB)
  • 57 Views
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Review

Review Article
Role of calcium-dependent protein kinases in chronic myeloid leukemia: combined effects of PKC and BCR-ABL signaling on cellular alterations during leukemia development
André L Mencalha, Stephany Corrêa & Eliana Abdelhay
Pages: 1247-1254
Published online: 08 Jul 2014
AbstractforRole of calcium-dependent protein kinases in chronic myeloid leukemia: combined effects of PKC and BCR-ABL signaling on cellular alterations during leukemia development | Full Text | References | PDF (661 KB)
  • 76 Views
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Original Research

Article
Lack of association between the XPD Lys751Gln polymorphism and colorectal cancer risk: a meta-analysis
Tao Zhang, Dong-ming Zhang, Da Zhao, Xiao-ming Hou, Shou-cheng Ma & Xiao-jun Liu
Pages: 1255-1260
Published online: 12 Jul 2014
AbstractforLack of association between the XPD Lys751Gln polymorphism and colorectal cancer risk: a meta-analysis | Full Text | References | PDF (359 KB)
  • 54 Views
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Article
Randomized double-blind trial of prophylactic topical Evozac® Calming Skin Spray for gefitinib-associated acne-like eruption
Yalan Wang, Yunpeng Yang, Jinxia Xu, Juan Yu, Xia Liu, Ruizhen Gao & Li Zhang
Pages: 1261-1266
Published online: 10 Jul 2014
AbstractforRandomized double-blind trial of prophylactic topical Evozac® Calming Skin Spray for gefitinib-associated acne-like eruption | Full Text | References | PDF (252.1 KB)
  • 61 Views
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Article
Discordance rate of HER2 status in primary breast carcinomas versus synchronous axillary lymph node metastases: a multicenter retrospective investigation
Antonio Ieni, Valeria Barresi, Rosario Caltabiano, Anna Maria Cascone, Rachele Del Sordo, Daniela Cabibi, Pio Zeppa, Salvatore Lanzafame, Angelo Sidoni, Vito Franco & Giovanni Tuccari
Pages: 1267-1272
Published online: 11 Jul 2014
AbstractforDiscordance rate of HER2 status in primary breast carcinomas versus synchronous axillary lymph node metastases: a multicenter retrospective investigation | Full Text | References | PDF (217.1 KB)
  • 83 Views
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Review

Review Article
Clinical utility of trabectedin for the treatment of ovarian cancer: current evidence
Floriana Mascilini, Giulia Amadio, Maria Grazia Di Stefano, Manuela Ludovisi, Alessia Di Legge, Carmine Conte, Rosa De Vincenzo, Caterina Ricci, Valeria Masciullo, Vanda Salutari, Giovanni Scambia & Gabriella Ferrandina
Pages: 1273-1284
Published online: 12 Jul 2014
AbstractforClinical utility of trabectedin for the treatment of ovarian cancer: current evidence | Full Text | References | PDF (2.1 MB)
  • 63 Views
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Original Research

Article
Salivary expression of soluble HER2 in breast cancer patients with positive and negative HER2 status
Fatna Laidi, Amal Bouziane, Amina Lakhdar, Samira Khabouze, Brahim Rhrab & Fatima Zaoui
Pages: 1285-1289
Published online: 14 Jul 2014
AbstractforSalivary expression of soluble HER2 in breast cancer patients with positive and negative HER2 status | Full Text | References | PDF (228.7 KB)
  • 68 Views
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Review

Review Article
Sorafenib in radioactive iodine-refractory well-differentiated metastatic thyroid cancer
Daniel C McFarland & Krzysztof J Misiukiewicz
Pages: 1291-1299
Published online: 15 Jul 2014
AbstractforSorafenib in radioactive iodine-refractory well-differentiated metastatic thyroid cancer | Full Text | References | PDF (275 KB)
  • 84 Views
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Original Research

Article
Prognostic significance of thymidylate synthase in postoperative non-small cell lung cancer patients
Hong-Yun Zhao, Guo-Wei Ma, Ben-Yan Zou, Mei Li, Su-Xia Lin, Li-Ping Zhao, Ying Guo, Yan Huang, Ying Tian, Dan Xie & Li Zhang
Pages: 1301-1310
Published online: 02 Dec 2022
AbstractforPrognostic significance of thymidylate synthase in postoperative non-small cell lung cancer patients | Full Text | References | PDF (1.9 MB)
  • 58 Views
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Article
Circulating tumor cells in the central and peripheral venous compartment – assessing hematogenous dissemination after transarterial chemoembolization of hepatocellular carcinoma
Zhu-Ting Fang, Wei Zhang, Guang-Zhi Wang, Bo Zhou, Guo-Wei Yang, Xu-Dong Qu, Rong Liu, Sheng Qian, Liang Zhu, Ling-Xiao Liu & Jian-Hua Wang
Pages: 1311-1318
Published online: 18 Jul 2014
AbstractforCirculating tumor cells in the central and peripheral venous compartment – assessing hematogenous dissemination after transarterial chemoembolization of hepatocellular carcinoma | Full Text | References | PDF (901.6 KB)
  • 105 Views
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Article
High expression of HEF1 is associated with poor prognosis in urinary bladder carcinoma
Qi Zhang, Hui-Ju Wang, Da-Hong Zhang, Guo-Qing Ru, Xu-Jun He & Ying-Yu Ma
Pages: 1319-1326
Published online: 21 Jul 2014
AbstractforHigh expression of HEF1 is associated with poor prognosis in urinary bladder carcinoma | Full Text | References | PDF (1.5 MB)
  • 62 Views
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Review

Review Article
MicroRNAs transported by exosomes in body fluids as mediators of intercellular communication in cancer
Iván Salido-Guadarrama, Sandra Romero-Cordoba, Oscar Peralta-Zaragoza, Alfredo Hidalgo-Miranda & Mauricio Rodríguez-Dorantes
Pages: 1327-1338
Published online: 21 Jul 2014
AbstractforMicroRNAs transported by exosomes in body fluids as mediators of intercellular communication in cancer | Full Text | References | PDF (5.8 MB)
  • 179 Views
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Case Report

Case Report
External iliac vein – transplant ureteral fistula combined with renal cell carcinoma: an unusual case of hematuria
Jin-dan Luo, Ben Liu, Ping Wang, Feng Zhou, Xiang-lai Xu, Shi-qi Li, Song-liang Cai & Yi-min Wang
Pages: 1339-1342
Published online: 23 Jul 2014
AbstractforExternal iliac vein – transplant ureteral fistula combined with renal cell carcinoma: an unusual case of hematuria | Full Text | References | PDF (889.1 KB)
  • 61 Views
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Original Research

Article
Comparison of short-term effect of thoracoscopic segmentectomy and thoracoscopic lobectomy for the solitary pulmonary nodule and early-stage lung cancer
Mingming Ren, Qingjun Meng, Wenyan Zhou, Fanyi Kong, Bo Yang, Jun Yuan, Dongwen Wu, Jing Zhang, Qiaqia Li, Yunshou Lin, Vidya Bhavani Viswanathan & Xiang Song
Pages: 1343-1347
Published online: 24 Jul 2014
AbstractforComparison of short-term effect of thoracoscopic segmentectomy and thoracoscopic lobectomy for the solitary pulmonary nodule and early-stage lung cancer | Full Text | References | PDF (192.6 KB)
  • 69 Views
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Review

Review Article
PD-1 as an emerging therapeutic target in renal cell carcinoma: current evidence
Scott S Tykodi
Pages: 1349-1359
Published online: 25 Jul 2014
AbstractforPD-1 as an emerging therapeutic target in renal cell carcinoma: current evidence | Full Text | References | PDF (795.4 KB)
  • 59 Views
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Case Report

Case Report
Paclitaxel- and/or cisplatin-induced ocular neurotoxicity: a case report and literature review
Ying Li, Junyu Li, Guoliang Pi & Wenyong Tan
Pages: 1361-1366
Published online: 31 Jul 2014
AbstractforPaclitaxel- and/or cisplatin-induced ocular neurotoxicity: a case report and literature review | Full Text | References | PDF (1 MB)
  • 118 Views
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Review

Review Article
Lapatinib for the treatment of breast cancer in the People’s Republic of China
Hongjiang Wang
Pages: 1367-1373
Published online: 31 Jul 2014
AbstractforLapatinib for the treatment of breast cancer in the People’s Republic of China | Full Text | References | PDF (232.1 KB)
  • 69 Views
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Original Research

Article
Potential implications of GRP58 expression and susceptibility of cervical cancer to cisplatin and thymoquinone-based therapy
Wan Abd Ghani Wan Nor Hafiza & Saiful Yazan Latifah
Pages: 1375-1387
Published online: 07 Aug 2014
AbstractforPotential implications of GRP58 expression and susceptibility of cervical cancer to cisplatin and thymoquinone-based therapy | Full Text | References | PDF (3.5 MB)
  • 110 Views
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Article
Silencing B7-H1 enhances the anti-tumor effect of bladder cancer antigen-loaded dendritic cell vaccine in vitro
Shuo Wang, Yonghua Wang, Jing Liu, Shixiu Shao, Xianjun Li, Jiannan Gao, Haitao Niu & Xinsheng Wang
Pages: 1389-1396
Published online: 02 Dec 2022
AbstractforSilencing B7-H1 enhances the anti-tumor effect of bladder cancer antigen-loaded dendritic cell vaccine in vitro | Full Text | References | PDF (1.3 MB)
  • 63 Views
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Article
PKN1 modulates TGFβ and EGF signaling in HEC-1-A endometrial cancer cell line
Sanaz Attarha, Ravi Kanth Rao Saini, Sonia Andersson, Miriam Mints & Serhiy Souchelnytskyi
Pages: 1397-1408
Published online: 04 Aug 2014
AbstractforPKN1 modulates TGFβ and EGF signaling in HEC-1-A endometrial cancer cell line | Full Text | References | PDF (6.8 MB)
  • 70 Views
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Article
Outcomes analysis of an alternative formulation of PEGylated liposomal doxorubicin in recurrent epithelial ovarian carcinoma during the drug shortage era
Jessica L Berger, Ashlee Smith, Kristin K Zorn, Paniti Sukumvanich, Alexander B Olawaiye, Joseph Kelley & Thomas C Krivak
Pages: 1409-1413
Published online: 08 Aug 2014
AbstractforOutcomes analysis of an alternative formulation of PEGylated liposomal doxorubicin in recurrent epithelial ovarian carcinoma during the drug shortage era | Full Text | References | PDF (164.9 KB)
  • 99 Views
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Article
Initial LDH level can predict the survival benefit from bevacizumab in the first-line setting in Chinese patients with metastatic colorectal cancer
Chenxi Yin, Chang Jiang, Fangxin Liao, Yuming Rong, Xiuyu Cai, Guifang Guo, Huijuan Qiu, Xuxian Chen, Bei Zhang, Wenzhuo He & Liangping Xia
Pages: 1415-1422
Published online: 11 Aug 2014
AbstractforInitial LDH level can predict the survival benefit from bevacizumab in the first-line setting in Chinese patients with metastatic colorectal cancer | Full Text | References | PDF (1.3 MB)
  • 62 Views
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Article
Oncogenic mutations are associated with histological subtypes but do not have an independent prognostic value in lung adenocarcinoma
Haichuan Hu, Yunjian Pan, Yuan Li, Lei Wang, Rui Wang, Yang Zhang, Hang Li, Ting Ye, Yiliang Zhang, Xiaoyang Luo, Longlong Shao, Zhengliang Sun, Deng Cai, Jie Xu, Qiong Lu, Youjia Deng, Lei Shen, Hongbin Ji, Yihua Sun & Haiquan Chen
Pages: 1423-1437
Published online: 13 Aug 2014
AbstractforOncogenic mutations are associated with histological subtypes but do not have an independent prognostic value in lung adenocarcinoma | Full Text | References | PDF (1.6 MB)
  • 66 Views
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Corrigendum

Correction
Sam68 is a novel marker for aggressive neuroblastoma [Corrigendum]
Page: 1439
Published online: 14 Aug 2014
CitationforSam68 is a novel marker for aggressive neuroblastoma [Corrigendum] | Full Text | PDF (93.1 KB)
  • 64 Views
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Original Research

Article
Isothermal multiple displacement amplification: a methodical approach enhancing molecular routine diagnostics of microcarcinomas and small biopsies
Fabian D Mairinger, Robert FH Walter, Claudia Vollbrecht, Thomas Hager, Karl Worm, Saskia Ting, Jeremias Wohlschläger, Paul Zarogoulidis, Konstantinos Zarogoulidis & Kurt W Schmid
Pages: 1441-1447
Published online: 13 Aug 2014
AbstractforIsothermal multiple displacement amplification: a methodical approach enhancing molecular routine diagnostics of microcarcinomas and small biopsies | Full Text | References | PDF (765.1 KB)
  • 83 Views
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Case Report

Case Report
Glucagonoma syndrome: a case report with focus on skin disorders
Sheng Fang, Shuang Li & Tao Cai
Pages: 1449-1453
Published online: 14 Aug 2014
AbstractforGlucagonoma syndrome: a case report with focus on skin disorders | Full Text | References | PDF (1.8 MB)
  • 65 Views
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Methodology

Article
A simple in vitro method for evaluating dendritic cell-based vaccinations
Phuc Van Pham, Nhung Thi Nguyen, Hoang Minh Nguyen, Lam Tan Khuat, Phong Minh Le, Viet Quoc Pham, Sinh Truong Nguyen & Ngoc Kim Phan
Pages: 1455-1464
Published online: 18 Aug 2014
AbstractforA simple in vitro method for evaluating dendritic cell-based vaccinations | Full Text | References | PDF (4 MB)
  • 84 Views
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Original Research

Article
RETRACTED ARTICLE: The coexpression and clinical significance of costimulatory molecules B7-H1, B7-H3, and B7-H4 in human pancreatic cancer
Yan Chen, Jing Sun, Hua Zhao, Dongming Zhu, Qiaoming Zhi, Shiduo Song, Lifeng Zhang, Songbing He, Yuting Kuang, Zixiang Zhang & Dechun Li
Pages: 1465-1472
Published online: 19 Aug 2014
AbstractforRETRACTED ARTICLE: The coexpression and clinical significance of costimulatory molecules B7-H1, B7-H3, and B7-H4 in human pancreatic cancer | PDF (1.3 MB)
  • 33 Views
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Corrigendum

Correction
Bevacizumab in combination with chemotherapy in platinum-sensitive ovarian cancer [Corrigendum]
Page: 1473
Published online: 20 Aug 2014
CitationforBevacizumab in combination with chemotherapy in platinum-sensitive ovarian cancer [Corrigendum] | Full Text | PDF (93.4 KB)
  • 57 Views
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Original Research

Article
High infiltration of tumor-associated macrophages in triple-negative breast cancer is associated with a higher risk of distant metastasis
Zhong-Yu Yuan, Rong-Zhen Luo, Rou-Jun Peng, Shu-Sen Wang & Cong Xue
Pages: 1475-1480
Published online: 21 Aug 2014
AbstractforHigh infiltration of tumor-associated macrophages in triple-negative breast cancer is associated with a higher risk of distant metastasis | Full Text | References | PDF (968.4 KB)
  • 202 Views
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Review

Review Article
miR-129 as a novel therapeutic target and biomarker in gastrointestinal cancer
Andrew Fesler, Haiyan Zhai & Jingfang Ju
Pages: 1481-1485
Published online: 21 Aug 2014
AbstractformiR-129 as a novel therapeutic target and biomarker in gastrointestinal cancer | Full Text | References | PDF (471.8 KB)
  • 62 Views
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Original Research

Article
The involvement of Kras gene 3′-UTR polymorphisms in risk of cancer and influence on patient response to anti-EGFR therapy in metastatic colorectal cancer: a meta-analysis
Hou-Qun Ying, Feng Wang, Bang-Shun He, Yu-Qin Pan, Tian-Yi Gao, Ye-Qiong Xu, Rui Li, Qi-Wen Deng, Hui-Lin Sun & Shu-Kui Wang
Pages: 1487-1496
Published online: 25 Aug 2014
AbstractforThe involvement of Kras gene 3′-UTR polymorphisms in risk of cancer and influence on patient response to anti-EGFR therapy in metastatic colorectal cancer: a meta-analysis | Full Text | References | PDF (577.6 KB)
  • 112 Views
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Review

Review Article
Cytoprotection “gone astray”: Nrf2 and its role in cancer
Claudia Geismann, Alexander Arlt, Susanne Sebens & Heiner Schäfer
Pages: 1497-1518
Published online: 02 Dec 2022
AbstractforCytoprotection “gone astray”: Nrf2 and its role in cancer | Full Text | References | PDF (1.3 MB)
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Article
Long-term outcomes from dose-escalated image-guided intensity-modulated radiotherapy with androgen deprivation: encouraging results for intermediate- and high-risk prostate cancer
Shea W Wilcox, Noel J Aherne, Linus C Benjamin, Bosco Wu, Thomaz de Campos Silva, Craig S McLachlan, Michael J McKay, Andrew J Last & Thomas P Shakespeare
Pages: 1519-1523
Published online: 30 Aug 2014
AbstractforLong-term outcomes from dose-escalated image-guided intensity-modulated radiotherapy with androgen deprivation: encouraging results for intermediate- and high-risk prostate cancer | Full Text | References | PDF (351.2 KB)
  • 101 Views
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Review

Review Article
ER-α36: a novel biomarker and potential therapeutic target in breast cancer
Xingyun Su, Xin Xu, Guangliang Li, Bingyi Lin, Jiang Cao & Lisong Teng
Pages: 1525-1533
Published online: 30 Aug 2014
AbstractforER-α36: a novel biomarker and potential therapeutic target in breast cancer | Full Text | References | PDF (1.1 MB)
  • 115 Views
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Article
An individual drug-therapy and genetic testing report of temporal bone verrucous carcinoma
Haolei Tan, Yong Liu, Gangcai Zhu, Leiming Pi, Donghai Huang & Xin Zhang
Pages: 1535-1540
Published online: 04 Sep 2014
AbstractforAn individual drug-therapy and genetic testing report of temporal bone verrucous carcinoma | Full Text | References | PDF (2.1 MB)
  • 51 Views
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Case Series

Bupivacaine administered intrathecally versus rectally in the management of intractable rectal cancer pain in palliative care
Iwona Zaporowska-Stachowiak, Grzegorz Kowalski, Jacek Łuczak, Katarzyna Kosicka, Aleksandra Kotlinska-Lemieszek, Maciej Sopata & Franciszek Główka
Pages: 1541-1550
Published online: 02 Dec 2022
AbstractforBupivacaine administered intrathecally versus rectally in the management of intractable rectal cancer pain in palliative care | Full Text | References | PDF (358.3 KB)
  • 73 Views
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Review

Review Article
Bevacizumab in Japanese patients with malignant glioma: from basic research to clinical trial
Shingo Takano, Eiichi Ishikawa, Kei Nakai, Masahide Matsuda, Tomohiko Masumoto, Tetsuya Yamamoto & Akira Matsumura
Pages: 1551-1562
Published online: 05 Sep 2014
AbstractforBevacizumab in Japanese patients with malignant glioma: from basic research to clinical trial | Full Text | References | PDF (3.4 MB)
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Article
HIF1α is an independent prognostic factor for overall survival in advanced primary epithelial ovarian cancer – a study of the OVCAD Consortium
Elena Ioana Braicu, Hrvoje Luketina, Rolf Richter, Dan Cacsire Castillo-Tong, Sandrina Lambrechts, Sven Mahner, Nicole Concin, Monika Mentze, Robert Zeillinger, Ignace Vergote & Jalid Sehouli
Pages: 1563-1569
Published online: 11 Sep 2014
AbstractforHIF1α is an independent prognostic factor for overall survival in advanced primary epithelial ovarian cancer – a study of the OVCAD Consortium | Full Text | References | PDF (261.7 KB)
  • 76 Views
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Article
Antiangiogenic cancer drug sunitinib exhibits unexpected proangiogenic effects on endothelial cells
Kerri-Ann Norton, Zheyi Han, Aleksander S Popel & Niranjan B Pandey
Pages: 1571-1582
Published online: 02 Dec 2022
AbstractforAntiangiogenic cancer drug sunitinib exhibits unexpected proangiogenic effects on endothelial cells | Full Text | References | PDF (1.6 MB)
  • 106 Views
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Article
MiR-206 functions as a tumor suppressor and directly targets K-Ras in human oral squamous cell carcinoma
Feiou Lin, Linjie Yao, Jin Xiao, DengFeng Liu & Zhenyu Ni
Pages: 1583-1591
Published online: 11 Sep 2014
AbstractforMiR-206 functions as a tumor suppressor and directly targets K-Ras in human oral squamous cell carcinoma | PDF (1.8 MB)
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Review

Review Article
Arsenic trioxide-based therapy in relapsed/refractory multiple myeloma patients: a meta-analysis and systematic review
Xuepeng He, Kai Yang, Peng Chen, Bing Liu, Yuan Zhang, Fang Wang, Zhi Guo, Xiaodong Liu, Jinxing Lou & Huiren Chen
Pages: 1593-1599
Published online: 10 Sep 2014
AbstractforArsenic trioxide-based therapy in relapsed/refractory multiple myeloma patients: a meta-analysis and systematic review | Full Text | References | PDF (296.4 KB)
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Article
Upregulation of micro-ribonucleic acid-128 cooperating with downregulation of PTEN confers metastatic potential and unfavorable prognosis in patients with primary osteosarcoma
Zheng Tian, Bin Guo, Mei Yu, Chong Wang, Haoshaqiang Zhang, Qingfu Liang, Kunli Jiang & Li Cao
Pages: 1601-1608
Published online: 15 Sep 2014
AbstractforUpregulation of micro-ribonucleic acid-128 cooperating with downregulation of PTEN confers metastatic potential and unfavorable prognosis in patients with primary osteosarcoma | Full Text | References | PDF (759.2 KB)
  • 65 Views
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Article
Isolation, detection, and immunomorphological characterization of circulating tumor cells (CTCs) from patients with different types of sarcoma using isolation by size of tumor cells: a window on sarcoma-cell invasion
Ludmilla T Domingos Chinen, Celso A Lopes Mello, Emne Ali Abdallah, Luciana MM Ocea, Marcilei E Buim, Natália M Breve, José Luiz Gasparini Junior, Marcello F Fanelli & Patrizia Paterlini-Bréchot
Pages: 1609-1617
Published online: 16 Sep 2014
AbstractforIsolation, detection, and immunomorphological characterization of circulating tumor cells (CTCs) from patients with different types of sarcoma using isolation by size of tumor cells: a window on sarcoma-cell invasion | Full Text | References | PDF (557.9 KB)
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Review

Review Article
Nanotetrac targets integrin αvβ3 on tumor cells to disorder cell defense pathways and block angiogenesis
Paul J Davis, Hung-Yun Lin, Thangirala Sudha, Murat Yalcin, Heng-Yuan Tang, Aleck Hercbergs, John T Leith, Mary K Luidens, Osnat Ashur-Fabian, Sandra Incerpi & Shaker A Mousa
Pages: 1619-1624
Published online: 18 Sep 2014
AbstractforNanotetrac targets integrin αvβ3 on tumor cells to disorder cell defense pathways and block angiogenesis | Full Text | References | PDF (204.6 KB)
  • 62 Views
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Article
Expression and clinical significance of the long non-coding RNA PVT1 in human gastric cancer
Jian Ding, Dan Li, Minzhen Gong, Jinpo Wang, Xunru Huang, Ting Wu & Chengdang Wang
Pages: 1625-1630
Published online: 18 Sep 2014
AbstractforExpression and clinical significance of the long non-coding RNA PVT1 in human gastric cancer | Full Text | References | PDF (629.1 KB)
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Review

Review Article
Profile of selumetinib and its potential in the treatment of melanoma
Dae Won Kim & Sapna P Patel
Pages: 1631-1639
Published online: 19 Sep 2014
AbstractforProfile of selumetinib and its potential in the treatment of melanoma | Full Text | References | PDF (559.6 KB)
  • 120 Views
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Case Report

Case Report
Cyclophosphamide-induced symptomatic hyponatremia, a rare but severe side effect: a case report
Shereen Elazzazy, Asmaa Elhassan Mohamed & Amaal Gulied
Pages: 1641-1645
Published online: 30 Sep 2014
AbstractforCyclophosphamide-induced symptomatic hyponatremia, a rare but severe side effect: a case report | Full Text | References | PDF (277 KB)
  • 98 Views
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Review

Review Article
The target therapy of ovarian clear cell carcinoma
Ying Jin, Yan Li & Lingya Pan
Pages: 1647-1652
Published online: 23 Sep 2014
AbstractforThe target therapy of ovarian clear cell carcinoma | Full Text | References | PDF (183.9 KB)
  • 94 Views
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Article
Clinical significance of UGT1A1 gene polymorphisms on irinotecan-based regimens as the treatment in metastatic colorectal cancer
Minmin Li, Zhehai Wang, Jun Guo, Jie Liu, Changzheng Li, Lin Liu, Huan Shi, Liyan Liu, Huihui Li, Chao Xie, Xia Zhang, Wenwen Sun, Shu Fang & Xiang Bi
Pages: 1653-1661
Published online: 23 Sep 2014
AbstractforClinical significance of UGT1A1 gene polymorphisms on irinotecan-based regimens as the treatment in metastatic colorectal cancer | Full Text | References | PDF (1 MB)
  • 140 Views
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Review

Review Article
The emerging role of class-3 semaphorins and their neuropilin receptors in oncology
Patrick Nasarre, Robert M Gemmill & Harry A Drabkin
Pages: 1663-1687
Published online: 24 Sep 2014
AbstractforThe emerging role of class-3 semaphorins and their neuropilin receptors in oncology | Full Text | References | PDF (743.8 KB)
  • 118 Views
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Review Article
Tumor heterogeneity and resistance to EGFR-targeted therapy in advanced nonsmall cell lung cancer: challenges and perspectives
Xinghua Cheng & Haiquan Chen
Pages: 1689-1704
Published online: 23 Sep 2014
AbstractforTumor heterogeneity and resistance to EGFR-targeted therapy in advanced nonsmall cell lung cancer: challenges and perspectives | Full Text | References | PDF (422.6 KB)
  • 127 Views
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Article
Tumor heterogeneity in the recurrence of epithelial ovarian cancer demonstrated by polycomb group proteins
Ting Gui, Huimin Bai, Jianfang Zeng, Zhaoji Zhong, Dongyan Cao, Quancai Cui, Jie Chen, Jiaxin Yang & Keng Shen
Pages: 1705-1716
Published online: 25 Sep 2014
AbstractforTumor heterogeneity in the recurrence of epithelial ovarian cancer demonstrated by polycomb group proteins | Full Text | References | PDF (2.8 MB)
  • 68 Views
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Article
Brentuximab vedotin for relapsed or refractory CD30+ Hodgkin lymphoma: a multicenter analysis from Asia
Qing-Ming Yang, Jung Yong Hong, Young Hyeh Ko, Shek-Ying Lin, Wing-Yan Au, Moon Ki Choi, Silvia Park, Seok Jin Kim & Won Seog Kim
Pages: 1717-1722
Published online: 26 Sep 2014
AbstractforBrentuximab vedotin for relapsed or refractory CD30+ Hodgkin lymphoma: a multicenter analysis from Asia | Full Text | References | PDF (554.3 KB)
  • 81 Views
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Article
PTK7 as a potential prognostic and predictive marker of response to adjuvant chemotherapy in breast cancer patients, and resistance to anthracycline drugs
Beyhan Ataseven, Angela Gunesch, Wolfgang Eiermann, Ronald E Kates, Bernhard Högel, Pjotr Knyazev, Axel Ullrich & Nadia Harbeck
Pages: 1723-1731
Published online: 06 Oct 2014
AbstractforPTK7 as a potential prognostic and predictive marker of response to adjuvant chemotherapy in breast cancer patients, and resistance to anthracycline drugs | Full Text | References | PDF (535.3 KB)
  • 69 Views
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Article
Overexpression of ETV4 protein in triple-negative breast cancer is associated with a higher risk of distant metastasis
Zhong-Yu Yuan, Ting Dai, Shu-Sen Wang, Rou-Jun Peng, Xing-Hua Li, Tao Qin, Li-Bing Song & Xi Wang
Pages: 1733-1742
Published online: 26 Sep 2014
AbstractforOverexpression of ETV4 protein in triple-negative breast cancer is associated with a higher risk of distant metastasis | Full Text | References | PDF (1.4 MB)
  • 103 Views
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Article
Prognostic value of preoperative inflammatory markers in Chinese patients with breast cancer
Minya Yao, Yu Liu, Hailong Jin, Xiaojiao Liu, Kezhen Lv, Haiyan Wei, Chengyong Du, Shuqian Wang, Bajin Wei & Peifen Fu
Pages: 1743-1752
Published online: 26 Sep 2014
AbstractforPrognostic value of preoperative inflammatory markers in Chinese patients with breast cancer | Full Text | References | PDF (1.5 MB)
  • 182 Views
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Article
Expression of YY1 correlates with progression and metastasis in esophageal squamous cell carcinomas
Judong Luo, Xin Jiang, LiLi Cao, Kejun Dai, Shuyu Zhang, Xin Ge, Xifa Zhou & Xujing Lu
Pages: 1753-1759
Published online: 26 Sep 2014
AbstractforExpression of YY1 correlates with progression and metastasis in esophageal squamous cell carcinomas | Full Text | References | PDF (1.5 MB)
  • 52 Views
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Article
Crenolanib, a PDGFR inhibitor, suppresses lung cancer cell proliferation and inhibits tumor growth in vivo
Ping Wang, Liqiang Song, Hui Ge, Pule Jin, Yifang Jiang, Wenxia Hu & Nan Geng
Pages: 1761-1768
Published online: 26 Sep 2014
AbstractforCrenolanib, a PDGFR inhibitor, suppresses lung cancer cell proliferation and inhibits tumor growth in vivo | Full Text | References | PDF (944.7 KB)
  • 111 Views
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Article
Conventional fractionated helical tomotherapy for patients with small to medium hepatocellular carcinomas without portal vein tumor thrombosis
Jinhong Jung, Moonkyoo Kong & Seong Eon Hong
Pages: 1769-1775
Published online: 26 Sep 2014
AbstractforConventional fractionated helical tomotherapy for patients with small to medium hepatocellular carcinomas without portal vein tumor thrombosis | Full Text | References | PDF (246.7 KB)
  • 61 Views
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Article
The expression sequence tag is an effective method for screening DNA segments that predict urinary bladder transitional cell carcinoma prognosis
Pei-Shan Yang, Yu-Chao Hsu, Yu-Hsiang Lin, Cheng-Pang Hou, Chien-Lun Chen, Phei-Lang Chang, Horng-Heng Juang & Ke-Hung Tsui
Pages: 1777-1781
Published online: 30 Sep 2014
AbstractforThe expression sequence tag is an effective method for screening DNA segments that predict urinary bladder transitional cell carcinoma prognosis | Full Text | References | PDF (936 KB)
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Case Report

Case Report
Capecitabine-induced cardiotoxicity: more evidence or clinical approaches to protect the patients’ heart?
Caterina Fontanella, Marianna Aita, Marika Cinausero, Giuseppe Aprile, Maria Grazia Baldin, Veronica Dusi, Chiara Lestuzzi, Gianpiero Fasola & Fabio Puglisi
Pages: 1783-1791
Published online: 29 Sep 2014
AbstractforCapecitabine-induced cardiotoxicity: more evidence or clinical approaches to protect the patients’ heart? | Full Text | References | PDF (3.7 MB)
  • 97 Views
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Review

Review Article
An evidence-based review of ixazomib citrate and its potential in the treatment of newly diagnosed multiple myeloma
Massimo Offidani, Laura Corvatta, Patrizia Caraffa, Silvia Gentili, Laura Maracci & Pietro Leoni
Pages: 1793-1800
Published online: 02 Dec 2022
AbstractforAn evidence-based review of ixazomib citrate and its potential in the treatment of newly diagnosed multiple myeloma | Full Text | References | PDF (359.9 KB)
  • 135 Views
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Article
Study of the mechanism of sonodynamic therapy in a rat glioma model
Dayong Song, Wu Yue, Zhiqiang Li, Jianhua Li, Jun Zhao & Ning Zhang
Pages: 1801-1810
Published online: 30 Sep 2014
AbstractforStudy of the mechanism of sonodynamic therapy in a rat glioma model | Full Text | References | PDF (1.9 MB)
  • 86 Views
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Article
A new inflammation index is useful for patients with esophageal squamous cell carcinoma
Ji-Feng Feng, Ying Huang & Qi Xun Chen
Pages: 1811-1815
Published online: 30 Sep 2014
AbstractforA new inflammation index is useful for patients with esophageal squamous cell carcinoma | Full Text | References | PDF (373 KB)
  • 54 Views
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Review

Review Article
Colorectal cancer in Chinese patients: current and emerging treatment options
Leung Li & Brigette BY Ma
Pages: 1817-1828
Published online: 02 Dec 2022
AbstractforColorectal cancer in Chinese patients: current and emerging treatment options | Full Text | References | PDF (283.3 KB)
  • 161 Views
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Article
Prognostic value of preoperative absolute lymphocyte count in recurrent hepatocellular carcinoma following thermal ablation: a retrospective analysis
Xin Li, Zhiyu Han, Zhigang Cheng, Jie Yu, Xiaoling Yu & Ping Liang
Pages: 1829-1835
Published online: 03 Oct 2014
AbstractforPrognostic value of preoperative absolute lymphocyte count in recurrent hepatocellular carcinoma following thermal ablation: a retrospective analysis | Full Text | References | PDF (596.2 KB)
  • 50 Views
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Review

Review Article
Profile of trebananib (AMG386) and its potential in the treatment of ovarian cancer
Michalis Liontos, Maria Lykka, Meletios-Athanasios Dimopoulos & Aristotle Bamias
Pages: 1837-1845
Published online: 02 Dec 2022
AbstractforProfile of trebananib (AMG386) and its potential in the treatment of ovarian cancer | Full Text | References | PDF (381.7 KB)
  • 101 Views
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Case Report

Case Report
Obstructive jaundice caused by intraductal metastasis of lung adenocarcinoma
Nobuaki Ochi, Daisuke Goto, Hiromichi Yamane, Tomoko Yamagishi, Yoshihiro Honda, Yasumasa Monobe, Hirofumi Kawamoto & Nagio Takigawa
Pages: 1847-1850
Published online: 07 Oct 2014
AbstractforObstructive jaundice caused by intraductal metastasis of lung adenocarcinoma | Full Text | References | PDF (952.6 KB)
  • 60 Views
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Article
Risk of treatment-related deaths with vascular endothelial growth factor receptor tyrosine kinase inhibitors: a meta-analysis of 41 randomized controlled trials
Shaodong Hong, Wenfeng Fang, Wenhua Liang, Yue Yan, Ting Zhou, Tao Qin, Xuan Wu, Yuxiang Ma, Yuanyuan Zhao, Yunpeng Yang, Zhihuang Hu, Cong Xue, Xue Hou, Yue Chen, Yan Huang, Hongyun Zhao & Li Zhang
Pages: 1851-1867
Published online: 07 Oct 2014
AbstractforRisk of treatment-related deaths with vascular endothelial growth factor receptor tyrosine kinase inhibitors: a meta-analysis of 41 randomized controlled trials | Full Text | References | PDF (717.3 KB)
  • 62 Views
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Article
Analysis of exfoliated gastric carcinoma cells attached on surgical supplies
Xiao-Fen Yu, Ying-Yu Ma, Xian-Qin Hu, Qin-Fang Zhang & Zai-Yuan Ye
Pages: 1869-1873
Published online: 10 Oct 2014
AbstractforAnalysis of exfoliated gastric carcinoma cells attached on surgical supplies | Full Text | References | PDF (1.4 MB)
  • 54 Views
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Article
Second-line docetaxel-based chemotherapy after failure of fluorouracil-based first-line treatment for advanced esophageal squamous cell carcinoma
Zhengbo Song & Yiping Zhang
Pages: 1875-1881
Published online: 13 Oct 2014
AbstractforSecond-line docetaxel-based chemotherapy after failure of fluorouracil-based first-line treatment for advanced esophageal squamous cell carcinoma | Full Text | References | PDF (612.7 KB)
  • 54 Views
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Article
Inhibition of Mus81 by siRNA enhances sensitivity to 5-FU in breast carcinoma cell lines
Ying Qian, Yanning Liu, Qiuyue Yan, Juan Lv, Xiaoyan Ni, Yunlu Wu & Xuejun Dong
Pages: 1883-1890
Published online: 02 Dec 2022
AbstractforInhibition of Mus81 by siRNA enhances sensitivity to 5-FU in breast carcinoma cell lines | Full Text | References | PDF (1.4 MB)
  • 72 Views
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Article
A survival analysis comparing women with ovarian low-grade serous carcinoma to those with high-grade histology
Ming Chen, Ying Jin, Yalan Bi, Jie Yin, Yongxue Wang & Lingya Pan
Pages: 1891-1899
Published online: 02 Dec 2022
AbstractforA survival analysis comparing women with ovarian low-grade serous carcinoma to those with high-grade histology | Full Text | References | PDF (1.6 MB)
  • 117 Views
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Review

Review Article
Clinical utility of recombinant adenoviral human p53 gene therapy: current perspectives
Guang-xia Chen, Shu Zhang, Xiao-hua He, Shi-yu Liu, Chao Ma & Xiao-Ping Zou
Pages: 1901-1909
Published online: 21 Oct 2014
AbstractforClinical utility of recombinant adenoviral human p53 gene therapy: current perspectives | Full Text | References | PDF (260.1 KB)
  • 234 Views
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Case Report

Case Report
More than 9 years of continuous trastuzumab treatment in metastatic breast cancer without cardiac toxicity: a case report and literature review
Florin Badulescu, Adriana Badulescu, Doru Paul, Carmen Florina Popescu & Cristina Florescu
Pages: 1911-1917
Published online: 17 Oct 2014
AbstractforMore than 9 years of continuous trastuzumab treatment in metastatic breast cancer without cardiac toxicity: a case report and literature review | Full Text | References | PDF (1.8 MB)
  • 59 Views
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Article
Metronomic capecitabine in gastroenteropancreatic neuroendrocrine tumors: a suitable regimen and review of the literature
Alberto Bongiovanni, Nada Riva, Sebastiano Calpona, Marianna Ricci, Erica Gunelli, Chiara Liverani, Federico La Manna, Alessandro De Vita, Manuela Monti, Stefano Severi, Federica Pieri, Elena Amadori, Riccardo Galassi, Davide Cavaliere, Alberto Zaccaroni, Andreas Tartaglia, Veronica Lunedei, Andrea Gardini, Laura Mercatali, Dino Amadori & Toni Ibrahim
Pages: 1919-1926
Published online: 02 Dec 2022
AbstractforMetronomic capecitabine in gastroenteropancreatic neuroendrocrine tumors: a suitable regimen and review of the literature | Full Text | References | PDF (274.7 KB)
  • 78 Views
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Review

Review Article
Angiopoietin 2 as a therapeutic target in hepatocellular carcinoma treatment: current perspectives
Manojkumar Bupathi, Ahmed Kaseb & Filip Janku
Pages: 1927-1932
Published online: 20 Oct 2014
AbstractforAngiopoietin 2 as a therapeutic target in hepatocellular carcinoma treatment: current perspectives | Full Text | References | PDF (362.8 KB)
  • 75 Views
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Review Article
Targeting the epithelial to mesenchymal transition in glioblastoma: the emerging role of MET signaling
Jin-Ku Lee, Kyeung Min Joo, Jeongwu Lee, Yeup Yoon & Do-Hyun Nam
Pages: 1933-1944
Published online: 02 Dec 2022
AbstractforTargeting the epithelial to mesenchymal transition in glioblastoma: the emerging role of MET signaling | Full Text | References | PDF (373.6 KB)
  • 119 Views
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Article
Ginsenoside Rg3 attenuates hepatoma VEGF overexpression after hepatic artery embolization in an orthotopic transplantation hepatocellular carcinoma rat model
Bo Zhou, Jianhua Wang & Zhiping Yan
Pages: 1945-1954
Published online: 21 Oct 2014
AbstractforGinsenoside Rg3 attenuates hepatoma VEGF overexpression after hepatic artery embolization in an orthotopic transplantation hepatocellular carcinoma rat model | Full Text | References | PDF (2.3 MB)
  • 72 Views
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Article
Downregulated Ku70 and ATM associated to poor prognosis in colorectal cancer among Chinese patients
Yuanfang Lu, Jingyan Gao & Yuanming Lu
Pages: 1955-1961
Published online: 24 Oct 2014
AbstractforDownregulated Ku70 and ATM associated to poor prognosis in colorectal cancer among Chinese patients | Full Text | References | PDF (425.4 KB)
  • 63 Views
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Article
The transcription factor KLF4 as an independent predictive marker for pathologic complete remission in breast cancer neoadjuvant chemotherapy: a case–control study
Min Jun Dong, Lin Bo Wang, Zhi Nong Jiang, Mei Jin, Wen Xian Hu & Jian Guo Shen
Pages: 1963-1969
Published online: 24 Oct 2014
AbstractforThe transcription factor KLF4 as an independent predictive marker for pathologic complete remission in breast cancer neoadjuvant chemotherapy: a case–control study | Full Text | References | PDF (852.2 KB)
  • 83 Views
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Review

Review Article
Profile of belinostat for the treatment of relapsed or refractory peripheral T-cell lymphoma
Andrew Bodiford, Megan Bodge, Mahsa S Talbott & Nishitha M Reddy
Pages: 1971-1977
Published online: 24 Oct 2014
AbstractforProfile of belinostat for the treatment of relapsed or refractory peripheral T-cell lymphoma | Full Text | References | PDF (585.8 KB)
  • 91 Views
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Article
B7-H3 expression in breast cancer and upregulation of VEGF through gene silence
Jing Sun, Yun-Di Guo, Xiao-Ning Li, Yang-Qin Zhang, Li Gu, Ping-Ping Wu, Guang-Hui Bai & Yang Xiao
Pages: 1979-1986
Published online: 29 Oct 2014
AbstractforB7-H3 expression in breast cancer and upregulation of VEGF through gene silence | Full Text | References | PDF (1.9 MB)
  • 144 Views
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Article
Prognostic significance of CDH13 hypermethylation and mRNA in NSCLC
Ruilin Xue, Cuili Yang, Fang Zhao & Dejia Li
Pages: 1987-1996
Published online: 31 Oct 2014
AbstractforPrognostic significance of CDH13 hypermethylation and mRNA in NSCLC | Full Text | References | PDF (874.1 KB)
  • 54 Views
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Review

Review Article
Ramucirumab: preclinical research and clinical development
Giuseppe Aprile, Erika Rijavec, Caterina Fontanella, Karim Rihawi & Francesco Grossi
Pages: 1997-2006
Published online: 29 Oct 2014
AbstractforRamucirumab: preclinical research and clinical development | Full Text | References | PDF (485 KB)
  • 192 Views
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Article
Gli3 silencing enhances cyclopamine suppressive effects on ovarian cancer
Hai-Yan Liu & Zheng Dong
Pages: 2007-2011
Published online: 30 Oct 2014
AbstractforGli3 silencing enhances cyclopamine suppressive effects on ovarian cancer | Full Text | References | PDF (440.2 KB)
  • 50 Views
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Article
The effects of ponatinib, a multi-targeted tyrosine kinase inhibitor, against human U87 malignant glioblastoma cells
Junxia Zhang, Qiang Zhou, Ge Gao, Yanfen Wang, Zhihui Fang, Guanlin Li, Mengfei Yu, Lingfei Kong, Ying Xing & Xiaoqun Gao
Pages: 2013-2019
Published online: 30 Oct 2014
AbstractforThe effects of ponatinib, a multi-targeted tyrosine kinase inhibitor, against human U87 malignant glioblastoma cells | Full Text | References | PDF (1.7 MB)
  • 136 Views
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Article
Proapoptotic and antiinvasive activity of Rac1 small molecule inhibitors on malignant glioma cells
Georgina A Cardama, Nazareno Gonzalez, Matias Ciarlantini, Lucia Gandolfi Donadío, María Julieta Comin, Daniel F Alonso, Pablo Lorenzano Menna & Daniel E Gomez
Pages: 2021-2033
Published online: 30 Oct 2014
AbstractforProapoptotic and antiinvasive activity of Rac1 small molecule inhibitors on malignant glioma cells | Full Text | References | PDF (2.2 MB)
  • 85 Views
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Review

Review Article
Antisense therapeutics in oncology: current status
Ammad Ahmad Farooqi, Zia ur Rehman & Jordi Muntane
Pages: 2035-2042
Published online: 03 Nov 2014
AbstractforAntisense therapeutics in oncology: current status | Full Text | References | PDF (210.2 KB)
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Original Research

Article
Clinical outcome of advanced and metastatic renal cell carcinoma treated with targeted therapy: is there a difference between young and old patients?
Guiming Zhang, Yao Zhu, Dahai Dong, Weijie Gu, Hailiang Zhang, Lijiang Sun & Dingwei Ye
Pages: 2043-2052
Published online: 03 Nov 2014
AbstractforClinical outcome of advanced and metastatic renal cell carcinoma treated with targeted therapy: is there a difference between young and old patients? | Full Text | References | PDF (816.8 KB)
  • 67 Views
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Article
The effect of laughter therapy on radiation dermatitis in patients with breast cancer: a single-blind prospective pilot study
Moonkyoo Kong, Sung Hee Shin, Eunmi Lee & Eun Kyoung Yun
Pages: 2053-2059
Published online: 04 Nov 2014
AbstractforThe effect of laughter therapy on radiation dermatitis in patients with breast cancer: a single-blind prospective pilot study | Full Text | References | PDF (339 KB)
  • 157 Views
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Article
Efficient utilization of EBUS-TBNA samples for both diagnosis and molecular analyses
F Oezkan, AM Khan, P Zarogoulidis, W Hohenforst-Schmidt, D Theegarten, K Yasufuku, T Nakajima, L Freitag & K Darwiche
Pages: 2061-2065
Published online: 10 Nov 2014
AbstractforEfficient utilization of EBUS-TBNA samples for both diagnosis and molecular analyses | Full Text | References | PDF (971.8 KB)
  • 103 Views
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Article
IL-1α -889 C/T polymorphism and cancer susceptibility: a meta-analysis
Daye Cheng, Yiwen Hao & Wenling Zhou
Pages: 2067-2074
Published online: 10 Nov 2014
AbstractforIL-1α -889 C/T polymorphism and cancer susceptibility: a meta-analysis | Full Text | References | PDF (558.1 KB)
  • 63 Views
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Article
EGFR-TKI therapy for patients with brain metastases from non-small-cell lung cancer: a pooled analysis of published data
Yun Fan, Xiaoling Xu & Conghua Xie
Pages: 2075-2084
Published online: 10 Nov 2014
AbstractforEGFR-TKI therapy for patients with brain metastases from non-small-cell lung cancer: a pooled analysis of published data | Full Text | References | PDF (443.5 KB)
  • 83 Views
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Article
Elevation of methylated DNA in KILLIN/PTEN in the plasma of patients with thyroid and/or breast cancer
Enders K Ng, Vivian Y Shin, Candy P Leung, Vivian W Chan, Fian B Law, Man T Siu, Brian H Lang, Edmond S Ma & Ava Kwong
Pages: 2085-2092
Published online: 11 Nov 2014
AbstractforElevation of methylated DNA in KILLIN/PTEN in the plasma of patients with thyroid and/or breast cancer | Full Text | References | PDF (667.6 KB)
  • 62 Views
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Article
Gemcitabine and oxaliplatinum: an effective regimen in patients with refractory and relapsing Hodgkin lymphoma
Antonio Gutierrez, Jose Rodriguez, Jordi Martinez-Serra, Jordi Gines, Pilar Paredes, Florencia Garcia, Javier Vercher, Josep Balanzat, Raquel del Campo, Pilar Galan, Miguel Morey, Antonia Sampol, Andres Novo, Leyre Bento, Lucia García, Joan Bargay & Joan Besalduch
Pages: 2093-2100
Published online: 13 Nov 2014
AbstractforGemcitabine and oxaliplatinum: an effective regimen in patients with refractory and relapsing Hodgkin lymphoma | Full Text | References | PDF (384.9 KB)
  • 92 Views
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Article
Natural history of histologically moderate cervical dysplasia in adolescent and young women
Salvador Piris, Victoria Bravo, Carmen Álvarez, Leticia Muñoz-Hernando, Estela Lorenzo-Hernando, Reyes Oliver, Laura Marqueta-Marques, Jose M Seoane-Ruiz, Alvaro Tejerizo-Garcia & Jesús S Jiménez
Pages: 2101-2106
Published online: 13 Nov 2014
AbstractforNatural history of histologically moderate cervical dysplasia in adolescent and young women | Full Text | References | PDF (1.1 MB)
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Case Report

Case Report
Pelvis metastasis from primary choroidal melanoma: a case report
Yan Xiong, Yun Lang, Chongqi Tu & Hong Duan
Pages: 2107-2110
Published online: 14 Nov 2014
AbstractforPelvis metastasis from primary choroidal melanoma: a case report | Full Text | References | PDF (1.1 MB)
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Original Research

Article
Topoisomerase II alpha and TLE3 as predictive markers of response to anthracycline and taxane-containing regimens for neoadjuvant chemotherapy in breast cancer
Tommaso Susini, Barbara Berti, Carlo Carriero, Ketty Tavella, Jacopo Nori, Ermanno Vanzi, Cecilia Molino, Mariarosaria Di Tommaso, Marco Santini, Valeria Saladino & Simonetta Bianchi
Pages: 2111-2120
Published online: 17 Nov 2014
AbstractforTopoisomerase II alpha and TLE3 as predictive markers of response to anthracycline and taxane-containing regimens for neoadjuvant chemotherapy in breast cancer | Full Text | References | PDF (2.5 MB)
  • 62 Views
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Case Series

Large malignant ovarian tumors during pregnancy: two cases
Dong Xu, Cheng Liang & Jing He
Pages: 2121-2125
Published online: 02 Dec 2022
AbstractforLarge malignant ovarian tumors during pregnancy: two cases | Full Text | References | PDF (598.1 KB)
  • 56 Views
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Original Research

Article
Comparison of clinical features, molecular alterations, and prognosis in morphological subgroups of lung invasive mucinous adenocarcinoma
Deng Cai, Hang Li, Rui Wang, Yuan Li, Yunjian Pan, Haichuan Hu, Yang Zhang, Ranxia Gong, Bin Pan, Yihua Sun & Haiquan Chen
Pages: 2127-2132
Published online: 18 Nov 2014
AbstractforComparison of clinical features, molecular alterations, and prognosis in morphological subgroups of lung invasive mucinous adenocarcinoma | Full Text | References | PDF (856.5 KB)
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Case Report

Case Report
Long-term complete remission in a patient with intravascular large B-cell lymphoma with central nervous system involvement
Takeshi Sawada, Yasushi Omuro, Takeshi Kobayashi, Tunekazu Hishima, Fumiaki Koizumi, Yusuke Kanemasa, Tatsu Shimoyama, Eisaku Sasaki & Yoshiharu Maeda
Pages: 2133-2136
Published online: 18 Nov 2014
AbstractforLong-term complete remission in a patient with intravascular large B-cell lymphoma with central nervous system involvement | Full Text | References | PDF (839.3 KB)
  • 70 Views
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Case Report
Post-nephrectomy foreign-body granuloma in the retroperitoneum mimicking lymph node metastasis of renal cell cancer
Jindan Luo, Yeqing Mao, Songliang Cai, Xiaoyong Shen, Shanwen Chen & Liping Xie
Pages: 2137-2141
Published online: 20 Nov 2014
AbstractforPost-nephrectomy foreign-body granuloma in the retroperitoneum mimicking lymph node metastasis of renal cell cancer | Full Text | References | PDF (1.7 MB)
  • 53 Views
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Case Report
FOLFIRI and regorafenib combination therapy with dose escalation of irinotecan as fourth-line treatment for patients with metastatic colon cancer according to UGT1A1 genotyping
Chien-Yu Lu, Yung-Sung Yeh, Ching-Wen Huang, Cheng-Jen Ma, Fang-Jung Yu & Jaw-Yuan Wang
Pages: 2143-2146
Published online: 21 Nov 2014
AbstractforFOLFIRI and regorafenib combination therapy with dose escalation of irinotecan as fourth-line treatment for patients with metastatic colon cancer according to UGT1A1 genotyping | Full Text | References | PDF (692.2 KB)
  • 92 Views
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Original Research

Article
Impact of type 2 diabetes mellitus on the prognosis of early stage triple-negative breast cancer in People’s Republic of China
Fang-Jing Ma, Zhe-Bin Liu, Li Qu, Shuang Hao, Guang-Yu Liu, Jiong Wu & Zhi-Ming Shao
Pages: 2147-2154
Published online: 27 Nov 2014
AbstractforImpact of type 2 diabetes mellitus on the prognosis of early stage triple-negative breast cancer in People’s Republic of China | Full Text | References | PDF (680 KB)
  • 79 Views
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Article
Neoadjuvant chemotherapy in locally advanced cervical carcinoma: which is better, intravenous or intra-arterial?
Ting Gui, Keng Shen, Yang Xiang, Lingya Pan, Jinghe Lang, Ming Wu, Huifang Huang, Dongyan Cao & Jiaxin Yang
Pages: 2155-2160
Published online: 26 Nov 2014
AbstractforNeoadjuvant chemotherapy in locally advanced cervical carcinoma: which is better, intravenous or intra-arterial? | Full Text | References | PDF (203 KB)
  • 65 Views
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Article
The association of apoptotic protein expressions sensitive to apoptosis gene, p73 and p53 with the prognosis of cervical carcinoma
Pinar Mega Tiber, Latife Baloglu, Sevgi Ozden, Zerrin Ozgen, Hazan Ozyurt, Makbule Eren & Oya Orun
Pages: 2161-2168
Published online: 26 Nov 2014
AbstractforThe association of apoptotic protein expressions sensitive to apoptosis gene, p73 and p53 with the prognosis of cervical carcinoma | Full Text | References | PDF (401.2 KB)
  • 64 Views
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Article
Cytologic surveillance versus immediate colposcopy for women with a cervical smear diagnosis of low-grade squamous intraepithelial lesion in a poor setting in Nigeria
LO Ajah, CO Chigbu, HE Onah, CA Iyoke, OL Lawani & PO Ezeonu
Pages: 2169-2173
Published online: 27 Nov 2014
AbstractforCytologic surveillance versus immediate colposcopy for women with a cervical smear diagnosis of low-grade squamous intraepithelial lesion in a poor setting in Nigeria | Full Text | References | PDF (201 KB)
  • 49 Views
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Article
Continuation of bevacizumab and addition of hormone therapy following weekly paclitaxel therapy in HER2-negative metastatic breast cancer
Andrés Redondo, Virginia Martínez, Pilar Zamora, Beatriz Castelo, Alvaro Pinto, Patricia Cruz, Oliver Higuera, Marta Mendiola, David Hardisson & Enrique Espinosa
Pages: 2175-2181
Published online: 02 Dec 2022
AbstractforContinuation of bevacizumab and addition of hormone therapy following weekly paclitaxel therapy in HER2-negative metastatic breast cancer | Full Text | References | PDF (291.4 KB)
  • 60 Views
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Article
Doxorubicin-conjugated bacteriophages carrying anti-MHC class I chain-related A for targeted cancer therapy in vitro
Achara Phumyen, Siriporn Jantasorn, Amonrat Jumnainsong & Chanvit Leelayuwat
Pages: 2183-2195
Published online: 02 Dec 2022
AbstractforDoxorubicin-conjugated bacteriophages carrying anti-MHC class I chain-related A for targeted cancer therapy in vitro | Full Text | References | PDF (1.3 MB)
  • 79 Views
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Article
EGF and EGFR genetic polymorphisms predict prognosis in locally advanced pharyngolaryngeal squamous cell carcinoma patients receiving postoperative concurrent chemoradiotherapy
Nai-Wen Su, Yi-Shing Leu, Jehn-Chuan Lee, Chung-Ji Liu, Chieh-Yuan Cheng, Jiun-Sheng Lin, Yu-Jen Chen, Chi-Kuan Chen, I-Chih Fang, Ruey-Kuen Hsieh & Yi-Fang Chang
Pages: 2197-2204
Published online: 28 Nov 2014
AbstractforEGF and EGFR genetic polymorphisms predict prognosis in locally advanced pharyngolaryngeal squamous cell carcinoma patients receiving postoperative concurrent chemoradiotherapy | Full Text | References | PDF (545.1 KB)
  • 68 Views
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Article
Role of urokinase plasminogen activator and plasminogen activator inhibitor mRNA expression as prognostic factors in molecular subtypes of breast cancer
Isabell Witzel, Karin Milde-Langosch, Marcus Schmidt, Thomas Karn, Sven Becker, Ralph Wirtz, Achim Rody, Elena Laakmann, Dina Schütze, Fritz Jänicke & Volkmar Müller
Pages: 2205-2213
Published online: 02 Dec 2022
AbstractforRole of urokinase plasminogen activator and plasminogen activator inhibitor mRNA expression as prognostic factors in molecular subtypes of breast cancer | Full Text | References | PDF (1.1 MB)
  • 63 Views
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Article
Multidrug resistance protein 1 localization in lipid raft domains and prostasomes in prostate cancer cell lines
Alba Gomà, Roser Mir, Fina Martínez-Soler, Avelina Tortosa, August Vidal, Enric Condom, Ricardo Pérez–Tomás & Pepita Giménez-Bonafé
Pages: 2215-2225
Published online: 02 Dec 2022
AbstractforMultidrug resistance protein 1 localization in lipid raft domains and prostasomes in prostate cancer cell lines | Full Text | References | PDF (7.4 MB)
  • 61 Views
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Review

Review Article
Microtubule inhibitor-based antibody–drug conjugates for cancer therapy
Kelsey Klute, Eleni Nackos, Shinsuke Tasaki, Daniel P Nguyen, Neil H Bander & Scott T Tagawa
Pages: 2227-2236
Published online: 03 Dec 2014
AbstractforMicrotubule inhibitor-based antibody–drug conjugates for cancer therapy | Full Text | References | PDF (250.8 KB)
  • 163 Views
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Review Article
Angiogenesis and antiangiogenic agents in cervical cancer
Federica Tomao, Anselmo Papa, Luigi Rossi, Eleonora Zaccarelli, Davide Caruso, Federica Zoratto, Pierluigi Benedetti Panici & Silverio Tomao
Pages: 2237-2248
Published online: 02 Dec 2022
AbstractforAngiogenesis and antiangiogenic agents in cervical cancer | Full Text | References | PDF (722.7 KB)
  • 150 Views
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Original Research

Article
Induction of multiple drug resistance in HMEC-1 endothelial cells after long-term exposure to sunitinib
Limin Huang, Chaoquan Hu, Mélanie Di Benedetto, Rémi Varin, Jielin Liu, Li Wang, Jean-Pierre Vannier, Jian Jin, Anne Janin, He Lu & Hong Li
Pages: 2249-2255
Published online: 04 Dec 2014
AbstractforInduction of multiple drug resistance in HMEC-1 endothelial cells after long-term exposure to sunitinib | Full Text | References | PDF (415.4 KB)
  • 81 Views
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