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Research Article

Article
Keratinocyte-derived small extracellular vesicles delay diabetic wound healing by triggering fibroblasts autophagy
Xiaosi Hong, Leiqin Cai, Lanlan Li, Dinghao Zheng, Jianghong Lin, Zhuoxian Liang, Wan Fu, Diefei Liang, Tingting Zeng, Kan Sun, Wei Wang, Sifan Chen, Meng Ren & Li Yan
Published online: 03 Jun 2024
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Open Access

Research Article

Article
A molecular and computational study of galbanic acid as a regulator of Sirtuin1 pathway in inhibiting lipid accumulation in HepG2 cells
Hadis Musavi, Hajar Shokri Afra, Farideh Sadeghkhani, Hossein Ghalehnoei, Abbas Khonakdar-Tarsi & Soleiman Mahjoub
Published online: 07 May 2024
  • 33 Views
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Review Article

Review Article
Hydrogen sulfide protects the endometrium in a rat model of type 1 diabetes via modulation of PPARγ/mTOR and Nrf-2/NF-κb pathways
Heba A. Abdel-Hamid, Heba Marey & Manar Fouli Gaber Ibrahim
Published online: 29 Apr 2024
  • 43 Views
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Research Article

Article
Humanin’s impact on pain markers and neuronal viability in diabetic neuropathy model
Muhammed Mirac Kelestemur, Ferah Bulut, Batuhan Bılgın, Munevver Gizem Hekım, Muhammed Adam, Sibel Ozcan, Mustafa Caglar Beker, Nalan Kaya Tektemur, Suat Tekin, Sinan Canpolat & Mete Ozcan
Published online: 10 Apr 2024
  • 112 Views
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Review Article

Review Article
Decrypting the multifaceted peripheral neuropathy based on molecular pathology and therapeutics: a comprehensive review
Praysha Patel, Krishna Thakkar, Div Shah, Umang Shah, Nilesh Pandey, Jayesh Patel & Alkeshkumar Patel
Published online: 08 Apr 2024
  • 128 Views
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Original Article

Article
Isorhamnetin as a potential therapeutic agent for diabetes mellitus through PGK1/AKT activation
Abdelrahim Alqudah, Esam Qnais, Mohammed Alqudah, Omar Gammoh, Mohammed Wedyan & Shtaywy S. Abdalla
Published online: 06 Mar 2024
  • 83 Views
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Review Article

Review Article
The triggering pathway, the metabolic amplifying pathway, and cellular transduction in regulation of glucose-dependent biphasic insulin secretion
Shradha Bisht & Mamta F Singh
Published online: 09 Jan 2024
  • 156 Views
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Original Article

Article
Tomatidine ameliorates high-fat-diet/streptozocin (HFD/STZ)-induced type 2 diabetes mellitus in mice
Li Cai, Baojian Hou & Juping Hu
Published online: 08 Jan 2024
  • 118 Views
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Review Article

Review Article
The oral microbial odyssey influencing chronic metabolic disease
Upasana Gupta & Priyankar Dey
Published online: 25 Dec 2023
  • 93 Views
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Original Article

Article
Bisphenol A induces non-alcoholic fatty liver disease by promoting the O-GlcNAcylation of NLRP3
Yonghong Zhang, Shujuan Han, Tian Li, Li Zhu & Feng Wei
Published online: 01 Dec 2023
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Open Access

Review Article

Review Article
Carvacrol is potential molecule for diabetes treatment
Mustafa Hoca, Eda Becer & Hafize Seda Vatansever
Published online: 29 Nov 2023
  • 149 Views
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Review Article

Review Article
Omentin roles in physiology and pathophysiology: an up-to-date comprehensive review
Aida A. Hussein, Noha A. Ahmed, Hader I. Sakr, Tarek Atia & Osama M. Ahmed
Published online: 23 Nov 2023
  • 198 Views
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Original Article

Article
Lactate entrance into the brain facilities adipose tissue lipolysis during exercise via circulating calcitonin gene-related peptide
Malihe Aveseh, Maryam Koushkie-Jahromi, Javad Nemati, Saeed Esmaeili-Mahani & Najmeh Sadat Hosseini
Published online: 20 Nov 2023
  • 90 Views
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Original Article

Article
Exendin-4, a GLP-1 receptor agonist, suppresses diabetic retinopathy in vivo and in vitro
Jufen Liu, Huijing Wang & Cuiting Huang
Published online: 03 Nov 2023
  • 768 Views
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Open Access

Review Article

Review Article
Berberine-induced glucagon-like peptide-1 and its mechanism for controlling type 2 diabetes mellitus: a comprehensive pathway review
Mostafa Araj-Khodaei, Mohammad Hossein Ayati, Akbar Azizi Zeinalhajlou, Tannaz Novinbahador, Mehdi Yousefi, Mahdi Shiri, Ata Mahmoodpoor, Ali Shamekh, Nazli Namazi & Sarvin Sanaie
Published online: 03 Nov 2023
  • 275 Views
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Research Article

Article
Reverse pharmacology approach to validate the diabetic wound-healing activity of Jatyadi thailam formulations in vitro on diabetic mimic environment
Kandasamy Swathi, Sundaravadivelu Sumathi, Kumar Somit & Sripathi K. Shubashini
Published online: 28 Oct 2023
  • 33 Views
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Research Article

Article
Andrographis paniculata (Burm. f.) Nees extract ameliorates insulin resistance in the insulin-resistant HepG2 cells via GLUT2/IRS-1 pathway
Sri Ningsih, Siska Andrina Kusumastuti, Nuralih Nuralih, Adam Arditya Fajriawan, Devi Permatasari, Prasetyawan Yunianto, Donny Ramadhan, Mayriska Tri Wulandari, Nisrina Firdausi, Nurhadi Nurhadi, Reni Giarni, Kurnia Agustini, Agung Eru Wibowo, Idah Rosidah, Tiya Novlita Rengganis, Ngatinem Ngatinem, Agus Himawan Subiantoro & Agus Supriyono
Published online: 25 Oct 2023
  • 166 Views
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Original Article

Article
Betaine regulates steroidogenesis, endoplasmic reticulum stress response and Nrf2/HO-1 antioxidant pathways in mouse Leydig cells under hyperglycaemia condition
Mohammad Reza Tabandeh, Elahe Davoodi, Vahid Bayati & Dian Dayer
Published online: 23 Oct 2023
  • 68 Views
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Original Article

Article
Leptin Rs7799039 polymorphism is associated with type 2 diabetes mellitus Egyptian patients
Amal Ahmed Mohamed, Dina M. Abo-Elmatty, Alaa S. Wahba, Omnia Ezzat Esmail, Hadeer Saied Mahmoud Salim, Wafaa Salah Mohammed Hegab, Mona Mostafa Farid Ghanem, Nadia Youssef Riad, Doaa Ghaith, Lamiaa I Daker, Shorouk Issa, Noha Hassan Radwan, Eman Sultan, Omar Mohamoud Azzam & Ehab A. M. El-Shoura
Published online: 15 Oct 2023
  • 85 Views
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Review Article

Review Article
Intermittent fasting in health and disease
Anubhav Mishra, Devika Sobha, Dimple Patel & Padmanaban S. Suresh
Published online: 13 Oct 2023
  • 1076 Views
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Research Article

Article
Ellagic acid reduces hepatic lipid contents through regulation of SIRT1 and AMPK in old rats
Mahdis Rahimi Naiini, Beydolah Shahouzehi, Mohammad Khaksari, Shahrzad Azizi, Niloufar Naghibi & Mahdieh Nazari-Robati
Published online: 10 Oct 2023
  • 74 Views
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Review Article

Review Article
The role of astrocytes response triggered by hyperglycaemia during spinal cord injury
C. Sámano & G. L. Mazzone
Published online: 05 Oct 2023
  • 62 Views
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Review Article

Review Article
Exploring plant-based alpha-glucosidase inhibitors: promising contenders for combatting type-2 diabetes
Sonali Kumari, Ravi Saini, Aditi Bhatnagar & Abha Mishra
Published online: 28 Sep 2023
  • 162 Views
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Research Article

Article
Dapagliflozin attenuates high glucose-and hypoxia/reoxygenation-induced injury via activating AMPK/mTOR-OPA1-mediated mitochondrial autophagy in H9c2 cardiomyocytes
Weiling Tu, Liang Li, Ming Yi, Junyu Chen, Xiaoqing Wang & Yan Sun
Published online: 01 Sep 2023
  • 174 Views
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Research Article

Article
Development of pancreatic islet cells in the extrahepatic bile ducts of rats with experimentally-induced metabolic syndrome
Maya Gulubova, Anna Tolekova, Dimitar Berbatov & Nurettin Aydogdu
Published online: 31 Aug 2023
  • 74 Views
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Review Article

Review Article
A review of the last decade: pancreatic cancer and type 2 diabetes
Jiaqi Wu, Liang Tang, Feng Zheng, Xun Chen & Lei Li
Published online: 30 Aug 2023
  • 153 Views
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Research Article

Article
Celastrol attenuates HFD-induced obesity and improves metabolic function independent of adiponectin signaling
Ling Ye, Yan Gao, Xuecheng Li, Xiaoshuang Liang, Yi Yang & Rufeng Zhang
Published online: 29 Aug 2023
  • 93 Views
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Review Article

Review Article
Role of oxidative stress in diabetes-induced complications and their management with antioxidants
Hasandeep Singh, Rajanpreet Singh, Arshdeep Singh, Harshbir Singh, Gurpreet Singh, Sarabjit Kaur & Balbir Singh
Published online: 11 Aug 2023
  • 253 Views
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Research Article

Article
The protective effects of hyperoxic pre-treatment in human-derived adipose tissue mesenchymal stem cells against in vitro oxidative stress and a rat model of renal ischaemia-reperfusion
Shahram Ahmadi Somaghian, Naser Pajouhi, Omid Dezfoulian, Afshin Pirnia, Ayat Kaeidi & Bahram Rasoulian
Published online: 28 Jul 2023
  • 41 Views
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Review Article

Review Article
Omentin-1 and diabetes: more evidence but far from enough
Jing Xu, Min Li, Xinli Jiang, Yuling Wang, Huijie Ma, Yaru Zhou, Meimei Tian & Yan Liu
Published online: 03 Jul 2023
  • 122 Views
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Review Article

Review Article
Molecular pathology and therapeutics of the diabetic foot ulcer; comprehensive reviews
Mansi Patel, Vaibhav Patel, Umang Shah & Alkeshkumar Patel
Published online: 09 Jun 2023
  • 299 Views
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Original Article

Article
Distinct profiles of bile acid metabolism caused by gut microbiota in kidney transplantation recipients revealed by 16S rRNA gene sequencing
Xiaoqiang Wu, Xiangyong Tian, Guanghui Cao, Zhiwei Wang, Xuan Wu, Yue Gu & Tianzhong Yan
Published online: 19 May 2023
  • 64 Views
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Review Article

Review Article
Circular RNAs as novel biomarkers in glomerular diseases
Seyyedeh Mina Hejazian, Yalda Rahbar Saadat, Seyed Mahdi Hosseiniyan Khatibi, Farahnoosh Farnood, Negin Farzamikia, Seyyed Sina Hejazian, Sepideh Batoumchi, Mohammadali M. Shoja, Sepideh Zununi Vahed & Mohammadreza Ardalan
Published online: 16 May 2023
  • 115 Views
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Original Article

Article
Silencing of dopamine receptor D5 inhibits the browning of 3T3-L1 adipocytes and ATP-consuming futile cycles in C2C12 muscle cells
Kiros Haddish & Jong Won Yun
Published online: 04 May 2023
  • 175 Views
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Original Article

Article
Glypican-3 knockdown inhibits the cell growth, stemness, and glycolysis development of hepatocellular carcinoma cells under hypoxic microenvironment through lactylation
Gebing Yao & Zihua Yang
Published online: 02 May 2023
  • 3549 Views
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Open Access

Original Article

Article
Inhibition of BMP4 alleviates diabetic retinal vascular dysfunction via the VEGF and smad1/5 signalling
Mingyuan Liu, Zhaoxia Li, Huiqin Zhang, Tingting Cao, Xueyan Feng, Xi Wang & Zhixue Wang
Published online: 19 Apr 2023
  • 85 Views
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Original Article

Article
hsa_circ_0000047 targeting miR-6720-5p/CYB5R2 axis alleviates inflammation and angiogenesis in diabetic retinopathy
Lin Liao, Jinpeng Chen & Sheng Peng
Published online: 27 Mar 2023
  • 100 Views
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Original Article

Article
Irisin expression and FNDC5 (rs3480) gene polymorphism in type 2 diabetic patients with and without CAD
Amera Morad Foad, Alshimaa Hafez, Wael Youssef, Ahmed Elsharawy Ahmed & Ali Mohamad Altaher
Published online: 02 Feb 2023
  • 142 Views
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Original Article

Article
Effects of central FGF21 infusion on the glucose homeostasis in rats (brain–pancreas axis)
Kevser Tanbek, Umit Yılmaz, Mehmet Gul, Ahmet Koç & Suleyman Sandal
Published online: 16 Jan 2023
  • 293 Views
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Review Article

Review
Regulating eEF2 and eEF2K in skeletal muscle by exercise
Kia Salimi, Masoomeh Alvandi, Mahdi Saberi Pirouz, Kamran Rakhshan & Glyn Howatson
Published online: 12 Jan 2023
  • 179 Views
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Review Article

Review
The predicted mechanisms and evidence of probiotics on type 2 diabetes mellitus (T2DM)
Ousman Bajinka, Kodzovi Sylvain Dovi, Lucette Simbilyabo, Ishmail Conteh & Yurong Tan
Published online: 11 Jan 2023
  • 255 Views
  • 1 CrossRef citations
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Original Article

Article
Apolipoprotein A-IV restrains fat accumulation in skeletal and myocardial muscles by inhibiting lipogenesis and activating PI3K–AKT signalling
Wenqian Zhang, Xiao-Huan Liu, Jin-Ting Zhou, Cheng Cheng, Jing Xu, Jun Yu & Xiaoming Li
Published online: 03 Jan 2023
  • 158 Views
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Original Article

Article
Silymarin inhibits the lipogenic pathway and reduces worsening of non-alcoholic fatty liver disease (NAFLD) in mice
Luana Cristina Faria Carvalho, Flávia Monteiro Ferreira, Bruna Vidal Dias, Daniela Couto de Azevedo, Gustavo Henrique Bianco de Souza, Matheus Marque Milagre, Marta de Lana, Paula Melo de Abreu Vieira, Cláudia Martins Carneiro, Sílvia de Paula-Gomes, Silvia Dantas Cangussu & Daniela Caldeira Costa
Published online: 03 Nov 2022
  • 180 Views
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Original Article

Article
Liquorice root extract and isoliquiritigenin attenuate high-fat diet-induced hepatic steatosis and damage in rats by regulating AMPK
Mohammed Abdo Yahya, Ghedeir M. Alshammari, Magdi A. Osman, Laila Naif Al-Harbi, Abu ElGasim A. Yagoub & Sahar Abdulaziz AlSedairy
Published online: 19 Sep 2022
  • 137 Views
  • 3 CrossRef citations
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Original Article

Article
Betulinic acid improves TNF-α-induced insulin resistance by inhibiting negative regulator of insulin signalling and inflammation-activated protein kinase in 3T3-L1 adipocytes
Hyun-Ah Lee, Jung-Kyung Lee & Ji-Sook Han
Published online: 07 Sep 2022
  • 165 Views
  • 2 CrossRef citations
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Review Article

Review
Sweat gland morphology and physiology in diabetes, neuropathy, and nephropathy: a review
Sudha Singaram, Kalpana Ramakrishnan, Jayashree Selvam, Mallika Senthil & Vigneswaran Narayanamurthy
Published online: 05 Sep 2022
  • 195 Views
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Original Article

Article
Activation of SIRT1 by silibinin improved mitochondrial health and alleviated the oxidative damage in experimental diabetic neuropathy and high glucose-mediated neurotoxicity
Islauddin Khan, Kumari Preeti, Rahul Kumar, Dharmendra Kumar Khatri & Shashi Bala Singh
Published online: 09 Aug 2022
  • 202 Views
  • 3 CrossRef citations
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Original Article

Article
Cyproheptadine, a SET7/9 inhibitor, reduces hyperglycaemia-induced ER stress alleviating inflammation and fibrosis in renal tubular epithelial cells
Himanshu Sankrityayan, Ajinath Kale, Vishwadeep Shelke & Anil Bhanudas Gaikwad
Published online: 01 Aug 2022
  • 181 Views
  • 1 CrossRef citations
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Original Article

Article
HECTD3 promotes NLRP3 inflammasome and pyroptosis to exacerbate diabetes-related cognitive impairment by stabilising MALT1 to regulate JNK pathway
Zhongfan Ruan, Yan Li & Yanfang Chen
Published online: 01 Aug 2022
  • 194 Views
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Original Article

Article
LncRNA H19 deficiency protects against the structural damage of glomerular endothelium in diabetic nephropathy via Akt/eNOS pathway
Xu Liu, Ming-Hui Li, Yun-Yun Zhao, Yu-Liang Xie, Xin Yu, Yu-Jing Chen, Peng Li, Wei-Fang Zhang & Tian-Tian Zhu
Published online: 22 Jul 2022
  • 118 Views
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