Drug and Chemical Toxicology, Volume 34, Issue 3 (2011)

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Drug and Chemical Toxicology, Volume 34, Issue 3 (2011)

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Research Article

Article
Soman-induced alterations of protein kinase C isozymes expression in five discrete areas of the rat brain
Golime RamaRao, Chandrakant Waghmare, Arvind Kumar Gupta & Bijoy Krishna Bhattacharya
Pages: 221-232
Published online: 07 Jun 2011
AbstractforSoman-induced alterations of protein kinase C isozymes expression in five discrete areas of the rat brain | Full Text | References | PDF (1.3 MB)
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Article
A comparison of the neuroprotective efficacy of individual oxime (HI-6) and combinations of oximes (HI-6+trimedoxime, HI-6+K203) in soman-poisoned rats
Jiri Kassa, Jana Zdarova Karasova & Sandra Tesarova
Pages: 233-239
Published online: 07 Jun 2011
AbstractforA comparison of the neuroprotective efficacy of individual oxime (HI-6) and combinations of oximes (HI-6+trimedoxime, HI-6+K203) in soman-poisoned rats | Full Text | References | PDF (607.2 KB)
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Article
Genotoxic assessment and toxicity evaluation of peginesatide in CByB6F1 hybrid mice
Kathryn W. Woodburn, Peter J. Schatz, Susan Wilson, Kei-Lai Fong, Valentine O. Wagner, Ramadevi Gudi, Ljubica Krsmanovic, Madhav Paranjpe & Sudhir A. Shah
Pages: 240-249
Published online: 07 Jun 2011
AbstractforGenotoxic assessment and toxicity evaluation of peginesatide in CByB6F1 hybrid mice | Full Text | References | PDF (903 KB)
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Article
Effects of dipotassium trioxohydroxytetrafluorotriborate (K2[B3O3F4OH]) on genetic material and inhibition of cell division in human cell cultures
Sanin Haveric, Anja Haveric, Kasim Bajrovic, Borivoj Galic & Milka Maksimovic
Pages: 250-254
Published online: 07 Jun 2011
AbstractforEffects of dipotassium trioxohydroxytetrafluorotriborate (K2[B3O3F4OH]) on genetic material and inhibition of cell division in human cell cultures | Full Text | References | PDF (749.1 KB)
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Article
Investigation of oxidative stress in blood, brain, kidney, and liver after oxime antidote HI-6 application in a mouse experimental model
Miroslav Pohanka, Jakub Sobotka, Hana Svobodova & Rudolf Stetina
Pages: 255-260
Published online: 07 Jun 2011
AbstractforInvestigation of oxidative stress in blood, brain, kidney, and liver after oxime antidote HI-6 application in a mouse experimental model | Full Text | References | PDF (666.6 KB)
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Article
Vernolide-A, a sesquiterpene lactone from Vernonia cinerea, induces apoptosis in B16F-10 melanoma cells by modulating p53 and caspase-3 gene expressions and regulating NF-κB-mediated bcl-2 activation
Poyil Pratheeshkumar & Girija Kuttan
Pages: 261-270
Published online: 07 Jun 2011
AbstractforVernolide-A, a sesquiterpene lactone from Vernonia cinerea, induces apoptosis in B16F-10 melanoma cells by modulating p53 and caspase-3 gene expressions and regulating NF-κB-mediated bcl-2 activation | Full Text | References | PDF (1.1 MB)
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Article
Antitumor activity of novel pyrrolo[2,3-d]pyrimidin-4-ones
Hoda Atapour-Mashhad, Zahra Tayarani-Najaran, Abolghasem Davoodnia, Raheleh Moloudi & Seyed Hadi Mousavi
Pages: 271-276
Published online: 07 Jun 2011
AbstractforAntitumor activity of novel pyrrolo[2,3-d]pyrimidin-4-ones | Full Text | References | PDF (936.7 KB)
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Article
Cytotoxicity and genotoxicity of titanium dioxide nanoparticles in UVA-irradiated normal peripheral blood lymphocytes
Su Jin Kang, Young Joon Lee, Byeong Mo Kim, Young Joo Choi & Hai Won Chung
Pages: 277-284
Published online: 07 Jun 2011
AbstractforCytotoxicity and genotoxicity of titanium dioxide nanoparticles in UVA-irradiated normal peripheral blood lymphocytes | Full Text | References | PDF (821.7 KB)
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Article
Genetic toxicology and preliminary in vivo studies of nitric oxide donor tocopherol analogs as potential new class of antiatherogenic agents
Mauricio Cabrera, Gloria V. López, Luis E. Gómez, Martín Breijo, Cristina Pintos, Horacio Botti, Stella Raymondo, Ariane Vettorazzi, Adela López de Ceráin, Antonio Monge, Homero Rubbo, Mercedes González & Hugo Cerecetto
Pages: 285-293
Published online: 07 Jun 2011
AbstractforGenetic toxicology and preliminary in vivo studies of nitric oxide donor tocopherol analogs as potential new class of antiatherogenic agents | Full Text | References | PDF (868 KB)
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Article
Methylphenidate lacks genotoxic effects in mouse peripheral blood erythrocytes
Ana L. Zamora-Perez, Blanca P. Lazalde-Ramos, Martha G. Sosa-Macías, Belinda C. Gómez-Meda, Olivia Torres-Bugarín & Guillermo M. Zúñiga-González
Pages: 294-299
Published online: 07 Jun 2011
AbstractforMethylphenidate lacks genotoxic effects in mouse peripheral blood erythrocytes | Full Text | References | PDF (718.1 KB)
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Article
Assessment of oral toxicity and safety of 9-cis-UAB30, a potential chemopreventive agent, in rat and dog studies
Matthew Lindeblad, Izet M. Kapetanovic, Kasim K. Kabirov, Nancy Dinger, Irina Mankovskaya, Robert Morrisey, Tomas Martín-Jiménez & Alexander Lyubimov
Pages: 300-310
Published online: 07 Jun 2011
AbstractforAssessment of oral toxicity and safety of 9-cis-UAB30, a potential chemopreventive agent, in rat and dog studies | Full Text | References | PDF (777.6 KB)
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Article
Prenatal developmental toxicity study of ethyl tertiary-butyl ether in rabbits
Yuzo Asano, Toshikazu Ishikura, Kayoko Kudoh, Ryo Haneda & Takako Endoh
Pages: 311-317
Published online: 07 Jun 2011
AbstractforPrenatal developmental toxicity study of ethyl tertiary-butyl ether in rabbits | Full Text | References | PDF (563.1 KB)
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Article
Effect of oral coadministration of artesunate with ferrous sulfate on rat liver mitochondrial membrane permeability transition
Mosebolatan V. Fafowora, Francis O. Atanu, Olayinka Sanya, Olufunso O. Olorunsogo & Ochuko L. Erukainure
Pages: 318-323
Published online: 07 Jun 2011
AbstractforEffect of oral coadministration of artesunate with ferrous sulfate on rat liver mitochondrial membrane permeability transition | Full Text | References | PDF (735.9 KB)
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Article
Antidermatophytic activity of pyrazolo[3,4-c]isothiazoles: a preliminary approach on 4-chlorophenyl derivative for evaluation of mutagenic and clastogenic effects on bacteria and human chromosomes in vitro
Damiano Rossi, Donatella Mares, Carlo Romagnoli, Elisa Andreotti, Stefano Manfredini & Chiara Beatrice Vicentini
Pages: 324-331
Published online: 07 Jun 2011
AbstractforAntidermatophytic activity of pyrazolo[3,4-c]isothiazoles: a preliminary approach on 4-chlorophenyl derivative for evaluation of mutagenic and clastogenic effects on bacteria and human chromosomes in vitro | Full Text | References | PDF (663.4 KB)
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Article
Induction of apoptosis by sulforaphane in highly metastatic B16F-10 melanoma cells
Thayele Purayil Hamsa, Punathil Thejass & Girija Kuttan
Pages: 332-340
Published online: 07 Jun 2011
AbstractforInduction of apoptosis by sulforaphane in highly metastatic B16F-10 melanoma cells | Full Text | References | PDF (821.1 KB)
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