Drug and Chemical Toxicology, Volume 36, Issue 4 (2013)

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Drug and Chemical Toxicology, Volume 36, Issue 4 (2013)

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Research Article

Article
Effect of celecoxib and L-NAME on global ischemia-reperfusion injury in the rat hippocampus
Sarah A. Abd El-Aal, Maha M. El-Sawalhi, Mona Seif-El-Nasr & Sanaa A. Kenawy
Pages: 385-395
Published online: 09 Jan 2013
AbstractforEffect of celecoxib and L-NAME on global ischemia-reperfusion injury in the rat hippocampus | Full Text | References | PDF (4 MB)
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Article
Investigation of antigenotoxic potential of Syzygium cumini extract (SCE) on cyclophosphamide-induced genotoxicity and oxidative stress in mice
Pankaj Tripathi, Rakesh K. Patel, Rina Tripathi & Nilesh R. Kanzariya
Pages: 396-402
Published online: 09 Jan 2013
AbstractforInvestigation of antigenotoxic potential of Syzygium cumini extract (SCE) on cyclophosphamide-induced genotoxicity and oxidative stress in mice | Full Text | References | PDF (149.5 KB)
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Article
Mechanisms of methimazole cytotoxicity in isolated rat hepatocytes
Reza Heidari, Hossein Babaei & Mohammad Eghbal
Pages: 403-411
Published online: 21 Dec 2012
AbstractforMechanisms of methimazole cytotoxicity in isolated rat hepatocytes | Full Text | References | PDF (607.8 KB)
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Article
The acute, developmental, genetic and inhalation toxicology of 2,3,3,3-tetrafluoropropene (HFO-1234yf)
Ann Tveit, George M. Rusch, Hans Muijser & Mariska-M. Tegelenbosch-Schouten
Pages: 412-420
Published online: 06 Jun 2013
AbstractforThe acute, developmental, genetic and inhalation toxicology of 2,3,3,3-tetrafluoropropene (HFO-1234yf) | Full Text | References | PDF (153.5 KB)
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Article
Effects of the neonicotinoid insecticide, clothianidin, on the reproductive organ system in adult male rats
Ramazan Bal, Gaffari Türk, Mehmet Tuzcu, Ökkes Yılmaz, Tuncay Kuloğlu, Gıyasettin Baydaş, Mustafa Naziroğlu, Zabit Yener, Ebru Etem & Zeynep Tuzcu
Pages: 421-429
Published online: 26 Mar 2013
AbstractforEffects of the neonicotinoid insecticide, clothianidin, on the reproductive organ system in adult male rats | Full Text | References | PDF (764.6 KB)
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Article
Genotoxicity assessment of NIM-76 and its formulation (pessary) in an in vitro Ames Salmonella/microsome assay and in vivo mouse bone marrow micronucleus test
Vinod Vijayan & Ghansham P. Meshram
Pages: 430-434
Published online: 26 Mar 2013
AbstractforGenotoxicity assessment of NIM-76 and its formulation (pessary) in an in vitro Ames Salmonella/microsome assay and in vivo mouse bone marrow micronucleus test | Full Text | References | PDF (129.8 KB)
  • 78 Views
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Article
Genotoxicity of structurally related copper and zinc containing Schiff base complexes
Omar F. Khabour, Na’il Saleh, Karem H. Alzoubi, Soleiman Hisaindee, Doaa Al-Fyad, Leena Al-Kaabi, Arwa Dodeen & Fatima T. Esmadi
Pages: 435-442
Published online: 26 Mar 2013
AbstractforGenotoxicity of structurally related copper and zinc containing Schiff base complexes | Full Text | References | PDF (405.1 KB)
  • 100 Views
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Article
A 26-week repeated-dose toxicity study of allisartan isoproxil in Sprague-Dawley rats
Yongzhen Liu, Hao Wang, Yumei Cheng, Jingjun Sun, Junwen Qiao, Henglei Lu, Liang Zhu, Likun Gong & Jin Ren
Pages: 443-450
Published online: 27 Mar 2013
AbstractforA 26-week repeated-dose toxicity study of allisartan isoproxil in Sprague-Dawley rats | Full Text | References | PDF (331.8 KB)
  • 170 Views
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Article
Genotoxicity and antioxidant enzyme activity induced by hexavalent chromium in Cyprinus carpio after in vivo exposure
Pavan Kumar, Ravindra Kumar, Naresh S. Nagpure, Prakash Nautiyal, Basdeo Kushwaha & Anurag Dabas
Pages: 451-460
Published online: 27 Mar 2013
AbstractforGenotoxicity and antioxidant enzyme activity induced by hexavalent chromium in Cyprinus carpio after in vivo exposure | Full Text | References | PDF (574.6 KB)
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Article
Retinal toxicity associated with high dose of meclofenamic acid
Hui Sun, Ying Wen, Nannan Ning, Jie An & Jingxin Li
Pages: 461-465
Published online: 27 Mar 2013
AbstractforRetinal toxicity associated with high dose of meclofenamic acid | Full Text | References | PDF (549.2 KB)
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Article
Protective effect of Calendula officinalis Linn. flowers against 3-nitropropionic acid induced experimental Huntington’s disease in rats
B. D. Shivasharan, Pandian Nagakannan, Boreddy Shivanandappa Thippeswamy, Veeresh Prabakar Veerapur, Punit Bansal & Mazhuvancherry K. Unnikrishnan
Pages: 466-473
Published online: 16 Apr 2013
AbstractforProtective effect of Calendula officinalis Linn. flowers against 3-nitropropionic acid induced experimental Huntington’s disease in rats | Full Text | References | PDF (380.4 KB)
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Article
Antiproliferative effect of pheophorbide a–mediated photodynamic therapy and its synergistic effect with doxorubicin on multiple drug-resistant uterine sarcoma cell MES-SA/Dx5
Karen Ka-Yan Cheung, Judy Yuet-Wa Chan & Kwok-Pui Fung
Pages: 474-483
Published online: 08 Apr 2013
AbstractforAntiproliferative effect of pheophorbide a–mediated photodynamic therapy and its synergistic effect with doxorubicin on multiple drug-resistant uterine sarcoma cell MES-SA/Dx5 | Full Text | References | PDF (1.4 MB)
  • 221 Views
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Article
Novel ferrocenyl-containing N-acetyl-2-pyrazolines inhibit in vitro angiogenesis and human lung cancer growth by interfering with F-actin stress fiber polimeryzation
Rakibe Beklem Bostancıoğlu, Seda Demirel, Günseli Turgut Cin & Ayse Tansu Koparal
Pages: 484-495
Published online: 08 Apr 2013
AbstractforNovel ferrocenyl-containing N-acetyl-2-pyrazolines inhibit in vitro angiogenesis and human lung cancer growth by interfering with F-actin stress fiber polimeryzation | Full Text | References | PDF (3.9 MB)
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Short Communication

Article
Study of oxidative, enzymatic mitochondrial respiratory chain function and apoptosis in perinatally HIV-infected pediatric patients
Constanza Morén, Glòria Garrabou, Antoni Noguera-Julian, Núria Rovira, Marc Catalán, Sandra Hernández, Ester Tobías, Francesc Cardellach, Clàudia Fortuny & Òscar Miró
Pages: 496-500
Published online: 27 Mar 2013
AbstractforStudy of oxidative, enzymatic mitochondrial respiratory chain function and apoptosis in perinatally HIV-infected pediatric patients | Full Text | References | PDF (322.3 KB)
  • 178 Views
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