Drug and Chemical Toxicology, Volume 46, Issue 5 (2023)

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Drug and Chemical Toxicology, Volume 46, Issue 5 (2023)

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Research Articles

Article
Mechanistic study of copper oxide, zinc oxide, cadmium oxide, and silver nanoparticles-mediated toxicity on the probiotic Lactobacillus reuteri
Aya M. Eid, Osama M. Sayed, Walaa Hozayen & Tarek Dishisha
Pages: 825-840
Published online: 05 Aug 2022
AbstractforMechanistic study of copper oxide, zinc oxide, cadmium oxide, and silver nanoparticles-mediated toxicity on the probiotic Lactobacillus reuteri | Full Text | References | PDF (4 MB) | EPUB | Supplemental
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Article
Acute, repeated inhalation toxicity, respiratory system irritation, and mutagenicity studies of 1,1,2,2-tetrafluoroethane (HFC-134) as the impurity in the pharmaceutical propellant 1,1,1,2-tetrafluoroethane (HFA-134a)
Yanjun Zhao, Huimin Sun, Fei Lin & Huiying Yang
Pages: 841-850
Published online: 03 Aug 2022
AbstractforAcute, repeated inhalation toxicity, respiratory system irritation, and mutagenicity studies of 1,1,2,2-tetrafluoroethane (HFC-134) as the impurity in the pharmaceutical propellant 1,1,1,2-tetrafluoroethane (HFA-134a) | Full Text | References | PDF (1.5 MB) | EPUB
  • 143 Views
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Article
Further insights into the impact of rebamipide on gentamicin-induced nephrotoxicity in rats: modulation of SIRT1 and β-catenin/cyclin D1 pathways
Heba S. Zaky, Somaia A. Abdel-Sattar, Albatoul Allam & Hebatalla I. Ahmed
Pages: 851-863
Published online: 28 Jul 2022
AbstractforFurther insights into the impact of rebamipide on gentamicin-induced nephrotoxicity in rats: modulation of SIRT1 and β-catenin/cyclin D1 pathways | Full Text | References | PDF (2.3 MB) | EPUB
  • 177 Views
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Article
Phytochemical composition, cytotoxicity, antioxidant and antimicrobial responses of Lavandula dentata L. grown under different levels of heavy metals stress condition
Souhila Terfi, Zineb Djerrad, Soumeya Krimat & Fatma Sadi
Pages: 864-878
Published online: 26 Jul 2022
AbstractforPhytochemical composition, cytotoxicity, antioxidant and antimicrobial responses of Lavandula dentata L. grown under different levels of heavy metals stress condition | Full Text | References | PDF (1.3 MB) | EPUB
  • 105 Views
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Article
Amelioration of modified chronic unpredictable stress using Celastrus paniculatus seed oil alone and in combination with fluoxetine
Sanjana Chahuan, Sania Grover & Shamsher Singh
Pages: 879-894
Published online: 09 Aug 2022
AbstractforAmelioration of modified chronic unpredictable stress using Celastrus paniculatus seed oil alone and in combination with fluoxetine | Full Text | References | PDF (3.6 MB) | EPUB
  • 113 Views
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Article
Specific and combined effects of dietary ethanol and arginine on Drosophila melanogaster
Maria M. Bayliak, Oleh I. Demianchuk, Dmytro V. Gospodaryov, Vitalii A. Balatskyi & Volodymyr I. Lushchak
Pages: 895-905
Published online: 28 Jul 2022
AbstractforSpecific and combined effects of dietary ethanol and arginine on Drosophila melanogaster | Full Text | References | PDF (2.1 MB) | EPUB
  • 165 Views
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Article
Long-term reproductive effects of benzo(a)pyrene at environmentally relevant dose on juvenile female rats
Ana Carolina Casali Reis, Bárbara Campos Jorge, Beatriz Rizzo Paschoalini, Jéssica Nogueira Bueno, Julia Stein, Suyane da Silva Moreira, Beatriz de Matos Manoel, Glaura Scantamburlo Alves Fernandes, Hamilton Hisano & Arielle Cristina Arena
Pages: 906-914
Published online: 31 Jul 2022
AbstractforLong-term reproductive effects of benzo(a)pyrene at environmentally relevant dose on juvenile female rats | Full Text | References | PDF (1.3 MB) | EPUB
  • 151 Views
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Article
Polyethyleneglycol-serine nanoparticles as a novel antidote for organophosphate poisoning: synthesis, characterization, in vitro and in vivo studies
Pedram Ebrahimnejad, Ali Davoodi, Hamid Irannejad, Javad Akhtari & Hamidreza Mohammadi
Pages: 915-930
Published online: 08 Aug 2022
AbstractforPolyethyleneglycol-serine nanoparticles as a novel antidote for organophosphate poisoning: synthesis, characterization, in vitro and in vivo studies | Full Text | References | PDF (2 MB) | EPUB
  • 114 Views
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Article
Cytotoxic effect and induction of apoptosis in human cervical cancer cells by a wood extract from Prosopis laevigata
Jorge Ibarra-Berumen, Mario Adán Moreno-Eutimio, Martha Rosales-Castro & Cynthia Ordaz-Pichardo
Pages: 931-943
Published online: 11 Aug 2022
AbstractforCytotoxic effect and induction of apoptosis in human cervical cancer cells by a wood extract from Prosopis laevigata | Full Text | References | PDF (3.2 MB) | EPUB
  • 227 Views
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Article
Mechanisms underlying citrinin-induced toxicity via oxidative stress and apoptosis-mediated by mitochondrial-dependent pathway in SH-SY5Y cells
Mahmoud Abudayyak, Ecem Fatma Karaman & Sibel Ozden
Pages: 944-954
Published online: 06 Sep 2022
AbstractforMechanisms underlying citrinin-induced toxicity via oxidative stress and apoptosis-mediated by mitochondrial-dependent pathway in SH-SY5Y cells | Full Text | References | PDF (1.8 MB) | EPUB
  • 316 Views
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Article
In vitro screening of genotoxicity and mutagenicity of pyriproxyfen in human lymphocytes and Salmonella typhimurium TA98 and TA100 strains
Havva Bugda, Banu Guven Ezer & Eyyup Rencuzogullari
Pages: 955-961
Published online: 18 Aug 2022
AbstractforIn vitro screening of genotoxicity and mutagenicity of pyriproxyfen in human lymphocytes and Salmonella typhimurium TA98 and TA100 strains | Full Text | References | PDF (951.4 KB) | EPUB
  • 257 Views
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Article
In silico QSAR modeling to predict the safe use of antibiotics during pregnancy
Feyza Kelleci Çelik & Gül Karaduman
Pages: 962-971
Published online: 22 Aug 2022
AbstractforIn silico QSAR modeling to predict the safe use of antibiotics during pregnancy | Full Text | References | PDF (1.2 MB) | EPUB | Supplemental
  • 266 Views
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Article
Sulfoxaflor insecticide exhibits cytotoxic or genotoxic and apoptotic potential via oxidative stress-associated DNA damage in human blood lymphocytes cell cultures
Cebrail Sınacı, Ayla Çelik, Derya Yetkin, Sertan Çevik & Gizem Güler
Pages: 972-983
Published online: 29 Aug 2022
AbstractforSulfoxaflor insecticide exhibits cytotoxic or genotoxic and apoptotic potential via oxidative stress-associated DNA damage in human blood lymphocytes cell cultures | Full Text | References | PDF (2 MB) | EPUB
  • 377 Views
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Article
Toxic and bioaccumulative effects of zinc nanoparticle exposure to goldfish, Carassius auratus (Linnaeus, 1758)
Hamed Ghafarifarsani, Seyed Aliakbar Hedayati, Morteza Yousefi, Seyed Hossein Hoseinifar, Peyman Yarahmadi, Seyedeh Soraya Mahmoudi & Hien Van Doan
Pages: 984-994
Published online: 19 Sep 2022
AbstractforToxic and bioaccumulative effects of zinc nanoparticle exposure to goldfish, Carassius auratus (Linnaeus, 1758) | Full Text | References | PDF (2.9 MB) | EPUB
  • 203 Views
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Article
Acute and subacute oral toxicity of artemisinin-hydroxychloroquine sulfate tablets in beagle dogs
Xiaobo Li, Jianjia Feng, Yueming Yuan, Shouya Zhang, Zhiyong Xu, Qin Xu, Jianping Song, Li Ru, Zheng Yuan & Wanting Wu
Pages: 995-1003
Published online: 29 Aug 2022
AbstractforAcute and subacute oral toxicity of artemisinin-hydroxychloroquine sulfate tablets in beagle dogs | Full Text | References | PDF (1.9 MB) | EPUB | Supplemental
  • 103 Views
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Article
Modulation of mitochondrial permeability transition pore opening by Myricetin and prediction of its-drug-like potential using in silico approach
Akinwunmi O. Adeoye, John A. Falode, Olabimpe C. Oladipupo, Tajudeen O. Obafemi, Babatunde J. Oso & Ige F. Olaoye
Pages: 1004-1014
Published online: 29 Aug 2022
AbstractforModulation of mitochondrial permeability transition pore opening by Myricetin and prediction of its-drug-like potential using in silico approach | Full Text | References | PDF (2.7 MB) | EPUB
  • 108 Views
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Article
Is a non-cytotoxic and non-genotoxic novel bioinspired dipeptide structure synthesis possible for theragnostic applications?
Merve Bacanlı, Jülide Secerli, Burcu Karayavuz, Onur Erdem & Hakan Erdoğan
Pages: 1015-1023
Published online: 01 Sep 2022
AbstractforIs a non-cytotoxic and non-genotoxic novel bioinspired dipeptide structure synthesis possible for theragnostic applications? | Full Text | References | PDF (1.8 MB) | EPUB
  • 276 Views
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Article
Pinealectomy and melatonin administration in rats: their effects on pulmonary edema induced by α-naphthylthiourea
Mohammed Raed Abdullah Al Gburi, Eyup Altinoz, Hulya Elbe, Melike Ozgul Onal, Umit Yilmaz, Nesibe Yilmaz, Melike Karayakali & Mehmet Demir
Pages: 1024-1034
Published online: 07 Sep 2022
AbstractforPinealectomy and melatonin administration in rats: their effects on pulmonary edema induced by α-naphthylthiourea | Full Text | References | PDF (2.7 MB) | EPUB
  • 278 Views
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Article
Curcumin improves the ability of donepezil to ameliorate memory impairment in Drosophila melanogaster: involvement of cholinergic and cnc/Nrf2-redox systems
Opeyemi Babatunde Ogunsuyi, Olayemi Philemon Aro, Ganiyu Oboh & Olawande Chinedu Olagoke
Pages: 1035-1043
Published online: 07 Sep 2022
AbstractforCurcumin improves the ability of donepezil to ameliorate memory impairment in Drosophila melanogaster: involvement of cholinergic and cnc/Nrf2-redox systems | Full Text | References | PDF (1.8 MB) | EPUB
  • 251 Views
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Article
Estimating the impact of drug addiction causes heart damage
Sheng-Huang Chang, Pei-Ying Pai, Chiung-Hung Hsu, Shibu Marthandam Asokan, Bruce Chi-Kang Tsai, Wen-Tsan Weng, Wei-Wen Kuo, Tzu-Ching Shih, Hui-Chuan Kao, William Shao-Tsu Chen & Chih-Yang Huang
Pages: 1044-1050
Published online: 10 Oct 2022
AbstractforEstimating the impact of drug addiction causes heart damage | Full Text | References | PDF (928.5 KB) | EPUB
  • 200 Views
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