Drug Development and Industrial Pharmacy, Volume 45, Issue 3 (2019)

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Drug Development and Industrial Pharmacy, Volume 45, Issue 3 (2019)

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Review Article

Review Article
Enhancing oral bioavailability of poorly soluble drugs with mesoporous silica based systems: opportunities and challenges
Kristen E. Bremmell & Clive A. Prestidge
Pages: 349-358
Published online: 20 Nov 2018
AbstractforEnhancing oral bioavailability of poorly soluble drugs with mesoporous silica based systems: opportunities and challenges | Full Text | References | PDF (2 MB) | EPUB
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Research Article

Article
Efficient method for isolation of exosomes from raw bovine milk
Marika Yamauchi, Kaori Shimizu, Matiur Rahman, Hinata Ishikawa, Hiroshi Takase, Shinya Ugawa, Ayaka Okada & Yasuo Inoshima
Pages: 359-364
Published online: 07 Nov 2018
AbstractforEfficient method for isolation of exosomes from raw bovine milk | Full Text | References | PDF (1.4 MB) | EPUB
  • 1192 Views
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Article
Formulation, optimization, hemocompatibility and pharmacokinetic evaluation of PLGA nanoparticles containing paclitaxel
Pooja Mittal, Harsh Vardhan, Gufran Ajmal, Gunjan Vasant Bonde, Ramit Kapoor, Ashu Mittal & Brahmeshwar Mishra
Pages: 365-378
Published online: 06 Dec 2018
AbstractforFormulation, optimization, hemocompatibility and pharmacokinetic evaluation of PLGA nanoparticles containing paclitaxel | Full Text | References | PDF (4 MB) | EPUB
  • 447 Views
  • 24 CrossRef citations
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Article
A comparison of drug substance predicted chemical stability with ICH compliant stability studies
H. E. Williams, J. Bright, E. Roddy, A. Poulton, S. D. Cosgrove, F. Turner, P. Harrison, A. Brookes, E. MacDougall, A. Abbott & C. Gordon
Pages: 379-386
Published online: 11 Nov 2018
AbstractforA comparison of drug substance predicted chemical stability with ICH compliant stability studies | Full Text | References | PDF (1.2 MB) | EPUB
  • 708 Views
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Article
Oral delivery of the anti-tumor necrosis factor α domain antibody, V565, results in high intestinal and fecal concentrations with minimal systemic exposure in cynomolgus monkeys
J. Scott Crowe, Kevin J. Roberts, Timothy M. Carlton, Luana Maggiore, Marion F. Cubitt, Keith P. Ray, Mary C. Donnelly, John C. Wahlich, Jonathan I. Humphreys, Jan R. Robinson, Gary A. Whale & Michael R. West
Pages: 387-394
Published online: 25 Nov 2018
AbstractforOral delivery of the anti-tumor necrosis factor α domain antibody, V565, results in high intestinal and fecal concentrations with minimal systemic exposure in cynomolgus monkeys | Full Text | References | PDF (1.2 MB) | EPUB
  • 4846 Views
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Open Access
Article
Design, preparation, and evaluation of liposomal gel formulations for treatment of acne: in vitro and in vivo studies
Sumit Madan, Chetan Nehate, Tarani Kanta Barman, Anurag S. Rathore & Veena Koul
Pages: 395-404
Published online: 30 Nov 2018
AbstractforDesign, preparation, and evaluation of liposomal gel formulations for treatment of acne: in vitro and in vivo studies | Full Text | References | PDF (2.1 MB) | EPUB | Supplemental
  • 684 Views
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Article
Development of a solid supersaturated self-nanoemulsifying preconcentrate (S-superSNEP) of fenofibrate using dimethylacetamide and a novel co-processed excipient
Manali Patki & Ketankumar Patel
Pages: 405-414
Published online: 02 Dec 2018
AbstractforDevelopment of a solid supersaturated self-nanoemulsifying preconcentrate (S-superSNEP) of fenofibrate using dimethylacetamide and a novel co-processed excipient | Full Text | References | PDF (1.8 MB) | EPUB | Supplemental
  • 328 Views
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Article
Comparative pharmacokinetic evaluation of extended release itopride HCl pellets with once daily tablet formulation in healthy human subjects: a two treatment, four period crossover study in fasted and fed condition
Muhammad Iqbal Nasiri, Rabia Ismail Yousuf, Muhammad Harris Shoaib, Fahad Siddiqui, Faaiza Qazi, Kamran Ahmed, Sohail Anwer & Kamran Zaheer
Pages: 415-422
Published online: 29 Nov 2018
AbstractforComparative pharmacokinetic evaluation of extended release itopride HCl pellets with once daily tablet formulation in healthy human subjects: a two treatment, four period crossover study in fasted and fed condition | Full Text | References | PDF (952.6 KB) | EPUB
  • 170 Views
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Articles

Article
Encapsulation of S-nitrosoglutathione: a transcriptomic validation
Ramia Safar, Rémi Houlgatte, Alain Le Faou, Carole Ronzani, Wen Wu, Luc Ferrari, Hélène Dubois-Pot-Schneider, Bertrand H. Rihn & Olivier Joubert
Pages: 423-429
Published online: 06 Dec 2018
AbstractforEncapsulation of S-nitrosoglutathione: a transcriptomic validation | Full Text | References | PDF (1.3 MB) | EPUB | Supplemental
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Research Article

Article
Two placebo-controlled crossover studies in healthy subjects to evaluate gastric acid neutralization by an alginate–antacid formulation (Gaviscon Double Action)
Joanne Wilkinson, Khalid Abd-Elaziz, Izaak den Daas, Johan Wemer, Michiel van Haastert, Victoria Hodgkinson, Michelle Foster & Cathal Coyle
Pages: 430-438
Published online: 02 Dec 2018
AbstractforTwo placebo-controlled crossover studies in healthy subjects to evaluate gastric acid neutralization by an alginate–antacid formulation (Gaviscon Double Action) | Full Text | References | PDF (2.2 MB) | EPUB
  • 339 Views
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Article
The efficacy of anti-VEGF antibody-modified liposomes loaded with paeonol in the prevention and treatment of hypertrophic scars
Jun Shi, Yanting Wu, Siyi Guo, Huidi Zhang, Guitian Chen & Xiaoqi Xu
Pages: 439-455
Published online: 17 Dec 2018
AbstractforThe efficacy of anti-VEGF antibody-modified liposomes loaded with paeonol in the prevention and treatment of hypertrophic scars | Full Text | References | PDF (5.7 MB) | EPUB
  • 255 Views
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Article
Systems pharmacology approach to investigate the molecular mechanisms of herb Rhodiola rosea L. radix
Wenjuan Zhang, Ying Huai, Zhiping Miao, Chu Chen, Mohamed Shahen, Siddiq Ur Rahman, Mahmoud Alagawany, Mohamed E. Abd El-Hack, Heping Zhao & Airong Qian
Pages: 456-464
Published online: 29 Nov 2018
AbstractforSystems pharmacology approach to investigate the molecular mechanisms of herb Rhodiola rosea L. radix | Full Text | References | PDF (2.3 MB) | EPUB | Supplemental
  • 904 Views
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Article
Study on the transdermal penetration mechanism of ibuprofen nanoemulsions
Li Zhengguang, Huang Jie, Zhang Yong, Cao Jiaojiao, Wang Xingqi & Chu Xiaoqin
Pages: 465-473
Published online: 22 Nov 2018
AbstractforStudy on the transdermal penetration mechanism of ibuprofen nanoemulsions | Full Text | References | PDF (1.6 MB) | EPUB
  • 262 Views
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Article
Unravelling the anticancer efficacy of 10-oxo-7-epidocetaxel: in vitro and in vivo results
Arehalli S. Manjappa & Rayasa S. Ramachandra Murthy
Pages: 474-484
Published online: 01 Jan 2019
AbstractforUnravelling the anticancer efficacy of 10-oxo-7-epidocetaxel: in vitro and in vivo results | Full Text | References | PDF (3.2 MB) | EPUB | Supplemental
  • 78 Views
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Article
Spray-dried pH-sensitive microparticles: effectual methodology to ameliorate the bioavailability of acid labile pravastatin
Mohammed M. Mehanna, Mohamad Ibrahim Shabarek & Hoda A. Elmartadny
Pages: 485-497
Published online: 09 Jan 2019
AbstractforSpray-dried pH-sensitive microparticles: effectual methodology to ameliorate the bioavailability of acid labile pravastatin | Full Text | References | PDF (1.8 MB) | EPUB
  • 127 Views
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Article
FLT3-specific curcumin micelles enhance activity of curcumin on FLT3-ITD overexpressing MV4-11 leukemic cells
Singkome Tima, Siriporn Okonogi, Chadarat Ampasavate, Cory Berkland & Songyot Anuchapreeda
Pages: 498-505
Published online: 24 Jan 2019
AbstractforFLT3-specific curcumin micelles enhance activity of curcumin on FLT3-ITD overexpressing MV4-11 leukemic cells | Full Text | References | PDF (2.4 MB) | EPUB
  • 284 Views
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Article
The inactivation of the non-enveloped enterovirus 71 (EV71) by a novel disinfectant gel formulation for topical use
Hai-Qiu Ma, Ying Wang, Yong-Hong Mao, Shu-Yan Wang, Yu-Pu Zhang, Chen-Qiang Zuo, Shao-Juan Liang & Jun-Wei Liu
Pages: 506-513
Published online: 15 Jan 2019
AbstractforThe inactivation of the non-enveloped enterovirus 71 (EV71) by a novel disinfectant gel formulation for topical use | Full Text | References | PDF (1.4 MB) | EPUB | Supplemental
  • 133 Views
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Article
pH-independent dissolution enhancement for multiple poorly water-soluble drugs by nano-sized solid dispersions based on hydrophobic–hydrophilic conjugates
Chau T. M. Tran, Phuong H. L. Tran & Thao T. D. Tran
Pages: 514-519
Published online: 24 Jan 2019
AbstractforpH-independent dissolution enhancement for multiple poorly water-soluble drugs by nano-sized solid dispersions based on hydrophobic–hydrophilic conjugates | Full Text | References | PDF (785.5 KB) | EPUB
  • 165 Views
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Corrections

Correction
Correction
Page: I
Published online: 22 Feb 2019
CitationforCorrection | Full Text | PDF (95.2 KB) | EPUB
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