Drug Metabolism Reviews, Volume 45, Issue 1 (2013)

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Drug Metabolism Reviews, Volume 45, Issue 1 (2013)

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Preface

Nuclear receptors in drug metabolism and beyond
Wen Xie & John Y. L. Chiang
Pages: 1-2
Published online: 21 Jan 2013
CitationforNuclear receptors in drug metabolism and beyond | Full Text | References | PDF (556.1 KB)
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Review Article

Review Article
Evaluation of pregnane X receptor (PXR)-mediated CYP3A4 drug-drug interactions in drug development
Michael W. Sinz
Pages: 3-14
Published online: 21 Jan 2013
AbstractforEvaluation of pregnane X receptor (PXR)-mediated CYP3A4 drug-drug interactions in drug development | Full Text | References | PDF (1,004.1 KB)
  • 1006 Views
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Review Article
Regulation of the cytosolic sulfotransferases by nuclear receptors
Melissa Runge-Morris, Thomas A. Kocarek & Charles N. Falany
Pages: 15-33
Published online: 21 Jan 2013
AbstractforRegulation of the cytosolic sulfotransferases by nuclear receptors | Full Text | References | PDF (1.1 MB)
  • 667 Views
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Review Article
Nuclear receptors and endobiotics glucuronidation: the good, the bad, and the UGT
Cyril Bigo, Sarah Caron, Amélie Dallaire-Théroux & Olivier Barbier
Pages: 34-47
Published online: 21 Jan 2013
AbstractforNuclear receptors and endobiotics glucuronidation: the good, the bad, and the UGT | Full Text | References | PDF (1,011.5 KB)
  • 497 Views
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Review Article
Nuclear-receptor–mediated regulation of drug– and bile-acid–transporter proteins in gut and liver
Jeff L. Staudinger, Sarah Woody, Mengxi Sun & Wenqi Cui
Pages: 48-59
Published online: 21 Jan 2013
AbstractforNuclear-receptor–mediated regulation of drug– and bile-acid–transporter proteins in gut and liver | Full Text | References | PDF (876.4 KB)
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Review Article
PXR antagonists and implication in drug metabolism
Sridhar Mani, Wei Dou & Matthew R. Redinbo
Pages: 60-72
Published online: 21 Jan 2013
AbstractforPXR antagonists and implication in drug metabolism | Full Text | References | PDF (1.5 MB)
  • 974 Views
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Review Article
Nuclear receptors in herb–drug interactions
Madhav Sachar & Xiaochao Ma
Pages: 73-78
Published online: 21 Jan 2013
AbstractforNuclear receptors in herb–drug interactions | Full Text | References | PDF (770.1 KB)
  • 347 Views
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Review Article
Xenobiotic-sensing nuclear receptors involved in drug metabolism: a structural perspective
Bret D. Wallace & Matthew R. Redinbo
Pages: 79-100
Published online: 05 Dec 2012
AbstractforXenobiotic-sensing nuclear receptors involved in drug metabolism: a structural perspective | Full Text | References | PDF (1.9 MB)
  • 700 Views
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Review Article
Cell-based systems to assess nuclear receptor activation and their use in drug development
Judy L. Raucy & Jerome M. Lasker
Pages: 101-109
Published online: 21 Jan 2013
AbstractforCell-based systems to assess nuclear receptor activation and their use in drug development | Full Text | References | PDF (698 KB)
  • 662 Views
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Review Article
Xenobiotic receptor humanized mice and their utility
Nico Scheer & C. Roland Wolf
Pages: 110-121
Published online: 23 Nov 2012
AbstractforXenobiotic receptor humanized mice and their utility | Full Text | References | PDF (1.3 MB)
  • 355 Views
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Review Article
Nuclear receptors in the cross-talk of drug metabolism and inflammation
Sabine Gerbal-Chaloin, Irena Iankova, Patrick Maurel & Martine Daujat-Chavanieu
Pages: 122-144
Published online: 21 Jan 2013
AbstractforNuclear receptors in the cross-talk of drug metabolism and inflammation | Full Text | References | PDF (866.2 KB)
  • 873 Views
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Review Article
Nuclear receptors in bile acid metabolism
Tiangang Li & John Y. L. Chiang
Pages: 145-155
Published online: 21 Jan 2013
AbstractforNuclear receptors in bile acid metabolism | Full Text | References | PDF (857.8 KB)
  • 1177 Views
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Review Article
Role of the constitutive androstane receptor in obesity and type 2 diabetes: a case study of the endobiotic function of a xenobiotic receptor
Mengxi Jiang & Wen Xie
Pages: 156-163
Published online: 21 Jan 2013
AbstractforRole of the constitutive androstane receptor in obesity and type 2 diabetes: a case study of the endobiotic function of a xenobiotic receptor | Full Text | References | PDF (686.6 KB)
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