Drug Metabolism Reviews, Volume 53, Issue 2 (2021)

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Drug Metabolism Reviews, Volume 53, Issue 2 (2021)

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Next Generation Drug Discovery and Development: Rethinking Translational Pharmacology for Accelerated Drug Development

Review Articles

Introduction to the mini special issue on next generation drug discovery and development: rethinking translational pharmacology for accelerated drug development
Chukwunonso K. Nwabufo
Pages: 171-172
Published online: 07 May 2021
AbstractforIntroduction to the mini special issue on next generation drug discovery and development: rethinking translational pharmacology for accelerated drug development | Full Text | PDF (237.3 KB) | EPUB
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Review Article
Recent advances in computational metabolite structure predictions and altered metabolic pathways assessment to inform drug development processes
Mary Alexandra Schleiff, Deepika Dhaware & Jasleen K. Sodhi
Pages: 173-187
Published online: 11 May 2021
AbstractforRecent advances in computational metabolite structure predictions and altered metabolic pathways assessment to inform drug development processes | Full Text | References | PDF (1.1 MB) | EPUB
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Recent developments in predicting CYP-independent metabolism
Nikhilesh V. Dhuria, Bianka Haro, Amit Kapadia, Khadjia A. Lobo, Bernice Matusow, Mary A. Schleiff, Christina Tantoy & Jasleen K. Sodhi
Pages: 188-206
Published online: 25 May 2021
AbstractforRecent developments in predicting CYP-independent metabolism | Full Text | References | PDF (1.6 MB) | EPUB
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Recent developments in in vitro and in vivo models for improved translation of preclinical pharmacokinetics and pharmacodynamics data
Jaydeep Yadav, Mehdi El Hassani, Jasleen Sodhi, Volker M. Lauschke, Jessica H. Hartman & Laura E. Russell
Pages: 207-233
Published online: 25 May 2021
AbstractforRecent developments in in vitro and in vivo models for improved translation of preclinical pharmacokinetics and pharmacodynamics data | Full Text | References | PDF (1.8 MB) | EPUB
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Prediction of drug-induced kidney injury in drug discovery
Priyanka Kulkarni
Pages: 234-244
Published online: 17 May 2021
AbstractforPrediction of drug-induced kidney injury in drug discovery | Full Text | References | PDF (811.6 KB) | EPUB
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Toxicogenomics of drug induced liver injury – from mechanistic understanding to early prediction.
Volker M. Lauschke
Pages: 245-252
Published online: 08 Mar 2021
AbstractforToxicogenomics of drug induced liver injury – from mechanistic understanding to early prediction. | Full Text | References | PDF (1.2 MB) | EPUB
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Open Access
Pharmacogenomics in the era of next generation sequencing – from byte to bedside
Laura E. Russell, Yitian Zhou, Ahmed A. Almousa, Jasleen K. Sodhi, Chukwunonso K. Nwabufo & Volker M. Lauschke
Pages: 253-278
Published online: 17 May 2021
AbstractforPharmacogenomics in the era of next generation sequencing – from byte to bedside | Full Text | References | PDF (2.1 MB) | EPUB
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Open Access
International Society for the Study of Xenobiotics (ISSX) New Investigator Group Committee 2019–2020 concluding remarks
Mary A. Schleiff & Jasleen K. Sodhi
Pages: 279-284
Published online: 09 Apr 2021
AbstractforInternational Society for the Study of Xenobiotics (ISSX) New Investigator Group Committee 2019–2020 concluding remarks | Full Text | References | PDF (701.3 KB) | EPUB
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