Expert Opinion on Drug Discovery, Volume 12, Issue 10 (2017)

Browse this journal
Sample our Bioscience journals, sign in here to start your access, Latest two full volumes FREE to you for 14 days

Expert Opinion on Drug Discovery, Volume 12, Issue 10 (2017)

See all volumes and issues
Vol 19, 2024 Vol 18, 2023 Vol 17, 2022 Vol 16, 2021 Vol 15, 2020 Vol 14, 2019 Vol 13, 2018 Volume 12, 2017 Vol 11, 2016 Vol 10, 2015 Vol 9, 2014 Vol 8, 2013 Vol 7, 2012 Vol 6, 2011 Vol 5, 2010 Vol 4, 2009 Vol 3, 2008 Vol 2, 2007 Vol 1, 2006
Download citations Download PDFs Download issue

Editorial

Editorial
Computer-aided drug design: time to play with novel chemical matter
Xavier Barril
Pages: 977-980
Published online: 03 Aug 2017
First Page PreviewforComputer-aided drug design: time to play with novel chemical matter | Full Text | References | PDF (405.8 KB)
  • 2589 Views
  • 13 CrossRef citations
  • 0Altmetric
Free Access

Review

Review
An overview of hydrogen deuterium exchange mass spectrometry (HDX-MS) in drug discovery
Glenn R. Masson, Meredith L. Jenkins & John E. Burke
Pages: 981-994
Published online: 17 Aug 2017
AbstractforAn overview of hydrogen deuterium exchange mass spectrometry (HDX-MS) in drug discovery | Full Text | References | PDF (1.7 MB)
  • 3363 Views
  • 93 CrossRef citations
  • 0Altmetric
Review
Animal inflammation-based models of depression and their application to drug discovery
Li Ma, Konstantin A. Demin, Tatyana O. Kolesnikova, Sergey L. Kharsko, Xiaokang Zhu, Xiaodong Yuan, Cai Song, Darya A. Meshalkina, Brian E. Leonard, Li Tian & Allan V. Kalueff
Pages: 995-1009
Published online: 17 Aug 2017
AbstractforAnimal inflammation-based models of depression and their application to drug discovery | Full Text | References | PDF (1.2 MB) | Supplemental
  • 642 Views
  • 53 CrossRef citations
  • 0Altmetric
Review
Organotypic cultures of cerebellar slices as a model to investigate demyelinating disorders
Frédéric Doussau, Jean-Luc Dupont, Dorine Neel, Aline Schneider, Bernard Poulain & Jean Louis Bossu
Pages: 1011-1022
Published online: 20 Jul 2017
AbstractforOrganotypic cultures of cerebellar slices as a model to investigate demyelinating disorders | Full Text | References | PDF (1.7 MB)
  • 1037 Views
  • 32 CrossRef citations
  • 0Altmetric
Review
Novel approaches to the design of bioavailable melanotropins
Yang Zhou & Minying Cai
Pages: 1023-1030
Published online: 12 Jul 2017
AbstractforNovel approaches to the design of bioavailable melanotropins | Full Text | References | PDF (833.5 KB)
  • 213 Views
  • 11 CrossRef citations
  • 0Altmetric
Review
Targeting intrinsic apoptosis and other forms of cell death by BH3-mimetics in glioblastoma
Georg Karpel-Massler, Chiaki Tsuge Ishida, Yiru Zhang, Marc-Eric Halatsch, M.-Andrew Westhoff & Markus D. Siegelin
Pages: 1031-1040
Published online: 20 Jul 2017
AbstractforTargeting intrinsic apoptosis and other forms of cell death by BH3-mimetics in glioblastoma | Full Text | References | PDF (1,015.5 KB)
  • 381 Views
  • 34 CrossRef citations
  • 0Altmetric
Review
New drug discovery approaches targeting recurrent mutations in chronic lymphocytic leukemia
Rupal Tripathi, Eriong Lee-Verges, Morihiro Higashi, Neus Gimenez, Laia Rosich, Monica Lopez-Guerra & Dolors Colomer
Pages: 1041-1052
Published online: 04 Aug 2017
AbstractforNew drug discovery approaches targeting recurrent mutations in chronic lymphocytic leukemia | Full Text | References | PDF (1.4 MB)
  • 328 Views
  • 2 CrossRef citations
  • 0Altmetric
Review
Therapeutic targeting of leukemic stem cells in acute myeloid leukemia – the biological background for possible strategies
Øystein Bruserud, Elise Aasebø, Maria Hernandez-Valladares, Galina Tsykunova & Håkon Reikvam
Pages: 1053-1065
Published online: 27 Jul 2017
AbstractforTherapeutic targeting of leukemic stem cells in acute myeloid leukemia – the biological background for possible strategies | Full Text | References | PDF (1.1 MB)
  • 613 Views
  • 32 CrossRef citations
  • 0Altmetric

Drug Discovery Case History

Article
The preclinical discovery and development of brexpiprazole for the treatment of major depressive disorder
Awais Aftab & Keming Gao
Pages: 1067-1081
Published online: 18 Jul 2017
AbstractforThe preclinical discovery and development of brexpiprazole for the treatment of major depressive disorder | Full Text | References | PDF (1.3 MB)
  • 590 Views
  • 5 CrossRef citations
  • 0Altmetric

Explore articles

Explore the most recently published articles

The coming of age of cyclic peptide drugs: an update on discovery technologies
Sophia You et al.
Review Article | Published online: 14 Jun 2024
Computer-aided drug discovery strategies for novel therapeutics for prostate cancer leveraging next-generating sequencing data
Weijie Zhang et al.
Review Article | Published online: 11 Jun 2024
The latest trends in peptide drug discovery and future challenges
Laszlo Otvos
Editorial | Published online: 11 Jun 2024
Free Access
The preclinical discovery and development of atogepant for migraine prophylaxis
Carlo Baraldi et al.
Article | Published online: 10 Jun 2024
Open Access
View all latest articles