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Volume 12, Issue 9

Expert Opinion on Drug Discovery

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Expert Opinion on Drug Discovery, Volume 12, Issue 9 (2017)

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Expert Opinion on Drug Discovery, Volume 12, Issue 9 (2017)

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Editorial

Representation and identification of activity cliffs

Jürgen Bajorath

Pages: 879-883

Published online: 12 Jul 2017

First Page PreviewforRepresentation and identification of activity cliffs | Full Text | References | PDF (588.4 KB)

2542 Views
36 CrossRef citations
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Free Access

Review

Lipophilicity and biomimetic properties to support drug discovery

Fotios Tsopelas, Constantinos Giaginis & Anna Tsantili-Kakoulidou

Pages: 885-896

Published online: 28 Jun 2017

AbstractforLipophilicity and biomimetic properties to support drug discovery | Full Text | References | PDF (870.1 KB)

820 Views
61 CrossRef citations
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Review

Biophysics: for HTS hit validation, chemical lead optimization, and beyond

Christine C. Genick & S. Kirk Wright

Pages: 897-907

Published online: 06 Jul 2017

AbstractforBiophysics: for HTS hit validation, chemical lead optimization, and beyond | Full Text | References | PDF (1 MB)

1063 Views
20 CrossRef citations
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Review

Approaches for discovering novel bioactive small molecules targeting autophagy

Hui-yun Hwang, Sung Min Cho & Ho Jeong Kwon

Pages: 909-923

Published online: 30 Jul 2017

AbstractforApproaches for discovering novel bioactive small molecules targeting autophagy | Full Text | References | PDF (1.6 MB)

349 Views
9 CrossRef citations
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Review

Stabilization of protein-protein interactions in drug discovery

Sebastian A. Andrei, Eline Sijbesma, Michael Hann, Jeremy Davis, Gavin O’Mahony, Matthew W. D. Perry, Anna Karawajczyk, Jan Eickhoff, Luc Brunsveld, Richard G. Doveston, Lech-Gustav Milroy & Christian Ottmann

Pages: 925-940

Published online: 11 Jul 2017

AbstractforStabilization of protein-protein interactions in drug discovery | Full Text | References | PDF (1.8 MB)

14469 Views
112 CrossRef citations
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Open Access

Review

The latest advances in the discovery of nitric oxide hybrid drug compounds

Ricardo A. M. Serafim, Filipe G. Pernichelle & Elizabeth I. Ferreira

Pages: 941-953

Published online: 30 Jun 2017

AbstractforThe latest advances in the discovery of nitric oxide hybrid drug compounds | Full Text | References | PDF (1.1 MB)

291 Views
27 CrossRef citations
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Review

Novel strategies for anti-aging drug discovery

Komal Saraswat & Syed Ibrahim Rizvi

Pages: 955-966

Published online: 11 Jul 2017

AbstractforNovel strategies for anti-aging drug discovery | Full Text | References | PDF (1.4 MB)

1144 Views
54 CrossRef citations
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Review

Using zebrafish as a model to study the role of epigenetics in hearing loss

Yingzi He, Beier Bao & Huawei Li

Pages: 967-975

Published online: 06 Jul 2017

AbstractforUsing zebrafish as a model to study the role of epigenetics in hearing loss | Full Text | References | PDF (948.5 KB)

562 Views
15 CrossRef citations
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