Expert Opinion on Drug Discovery, Volume 15, Issue 2 (2020)

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Expert Opinion on Drug Discovery, Volume 15, Issue 2 (2020)

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Editorial

Editorial
What is the current value of fluorescence polarization assays in small molecule screening?
Asko Uri & Olivier Etebe Nonga
Pages: 131-133
Published online: 13 Dec 2019
First Page PreviewforWhat is the current value of fluorescence polarization assays in small molecule screening? | Full Text | References | PDF (519.3 KB) | EPUB
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Editorial
Is anti-ageing drug discovery becoming a reality?
Alexey Moskalev
Pages: 135-138
Published online: 10 Dec 2019
First Page PreviewforIs anti-ageing drug discovery becoming a reality? | Full Text | References | PDF (486.1 KB) | EPUB
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Special Report

Article
Assays used to assess biosimilarity of therapies for inflammatory bowel disease
Ido Veisman & Shomron Ben-Horin
Pages: 139-144
Published online: 05 Dec 2019
AbstractforAssays used to assess biosimilarity of therapies for inflammatory bowel disease | Full Text | References | PDF (518.4 KB) | EPUB
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Perspective

Article
Why hasn’t there been more progress in new Chagas disease drug discovery?
Alane Beatriz Vermelho, Giseli Capaci Rodrigues & Claudiu T. Supuran
Pages: 145-158
Published online: 31 Oct 2019
AbstractforWhy hasn’t there been more progress in new Chagas disease drug discovery? | Full Text | References | PDF (1.4 MB) | EPUB
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Review

Review
Toward the identification of ZDHHC enzymes required for palmitoylation of viral protein as potential drug targets
Mohamed Rasheed Gadalla & Michael Veit
Pages: 159-177
Published online: 06 Dec 2019
AbstractforToward the identification of ZDHHC enzymes required for palmitoylation of viral protein as potential drug targets | Full Text | References | PDF (1.9 MB) | EPUB
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Review
An overview of human leptospirosis vaccine design and future perspectives
Carolina R. Felix, Bianca S. Siedler, Liana N. Barbosa, Gabriana R. Timm, Johnjoe McFadden & Alan J. A. McBride
Pages: 179-188
Published online: 28 Nov 2019
AbstractforAn overview of human leptospirosis vaccine design and future perspectives | Full Text | References | PDF (1.2 MB) | EPUB | Supplemental
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Review
New directions in antimalarial target validation
Fernando A. Batista, Benjamin Gyau, Juliana F. Vilacha, Soraya S. Bosch, Sergey Lunev, Carsten Wrenger & Matthew R. Groves
Pages: 189-202
Published online: 20 Jan 2020
AbstractforNew directions in antimalarial target validation | Full Text | References | PDF (1.9 MB) | EPUB
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Open Access
Review
Drug screening of rhodanine derivatives for antibacterial activity
Suresh Maddila, Sridevi Gorle & Sreekantha B Jonnalagadda
Pages: 203-229
Published online: 28 Nov 2019
AbstractforDrug screening of rhodanine derivatives for antibacterial activity | Full Text | References | PDF (6.7 MB) | EPUB
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Review
Emerging opportunities of exploiting mycobacterial electron transport chain pathway for drug-resistant tuberculosis drug discovery
Kuldeep K. Roy & Mushtaq Ahmad Wani
Pages: 231-241
Published online: 27 Nov 2019
AbstractforEmerging opportunities of exploiting mycobacterial electron transport chain pathway for drug-resistant tuberculosis drug discovery | Full Text | References | PDF (1.6 MB) | EPUB
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Review
Current discovery strategies for hepatocellular carcinoma therapeutics
Qiuzi Dai, Cunlong Zhang, Zigao Yuan, Qinsheng Sun & Yuyang Jiang
Pages: 243-258
Published online: 06 Dec 2019
AbstractforCurrent discovery strategies for hepatocellular carcinoma therapeutics | Full Text | References | PDF (2.4 MB) | EPUB
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