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‘Latest articles’ are articles accepted for publication in this journal but not yet published in a volume/issue. Articles are removed from the ‘Latest articles’ list when they are published in a volume/issue. Latest articles are citable using the author(s), year of online publication, article title, journal and article DOI.

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Review

Review Article
Clinical application and potential pluripotent effects of hepatocyte growth factor in spinal cord injury regeneration
Shogo Hashimoto, Narihito Nagoshi, Masaya Nakamura & Hideyuki Okano
Published online: 29 May 2024
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Review

Review Article
Clinical application and potential pluripotent effects of hepatocyte growth factor in spinal cord injury regeneration
Shogo Hashimoto, Narihito Nagoshi, Masaya Nakamura & Hideyuki Okano
Published online: 29 May 2024
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Review

Review Article
Inflammation and Huntington’s disease – a neglected therapeutic target?
Sophie E. Field, Annabel J. Curle & Roger A. Barker
Published online: 29 May 2024
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Open Access

Review

Review Article
Inflammation and Huntington’s disease – a neglected therapeutic target?
Sophie E. Field, Annabel J. Curle & Roger A. Barker
Published online: 29 May 2024
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Open Access

Plain Language Summary

Plain Language Summary of Publication
Plain Language Summary of the PAISLEY study: deucravacitinib as a treatment for people with systemic lupus erythematosus
Eric F. Morand, Marilyn Pike, J Merrill, Ronald F van Vollenhoven, Victoria P Werth, Coburn Hobar, Nikolay Delev, Vaishali Shah, Brian Sharkey, Thomas Wegman, Ian Catlett, Subhashis Banerjee & Shalabh Singhal
Published online: 29 May 2024
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Open Access

Original Research

Article
Safety, pharmacokinetics and pharmacodynamics of SHR-1703, an innovative long-acting anti-interleukin-5 monoclonal antibody, in healthy subjects: a randomized, double-blind, dose-escalation, placebo-controlled phase I study
Ling Yang, Yuan Fang, Yuan Luo, Meng Fu, Kai Shen & Zhu Luo
Accepted author version posted online: 28 May 2024
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Review Article

Review Article
The role of extracellular vesicles in immune cell exhaustion and resistance to immunotherapy
Ava Aghakhani, Parmida Sadat Pezeshki & Nima Rezaei
Accepted author version posted online: 25 May 2024
Extracellular vesicles contribute to cell signaling in various stages of tumor progression including oncogenesis, angiogenesis, and metastasis. They are also capable of inhibiting immune responses and impairing immunotherapies. However, their distinctive characteristics are currently used to produce therapeutic nanoparticles such as novel cancer vaccines, engineered EVS, and EV mimetics. EV: extracellular vesicle; ICI: immune checkpoint inhibitor; MAB: monoclonal antibody
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Review

Review Article
Epidermal growth factor receptor antagonists in colorectal cancer: emerging strategies for precision therapy
Nadia Saoudi González, Paola Valeria Marchese, Iosune Baraibar, Javier Ros, Francesc Salvà, Marta Rodríguez, Clara Salvà, Caterina Vaghi, Adriana Alcaraz, Ariadna García, Josep Tabernero & Elena Élez
Published online: 22 May 2024
  • 24 Views
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Review

Review Article
Novel investigational drugs for alopecia areata and future perspectives
Ivana Chim, Ragini Ghiya, Rodney D Sinclair & Samantha Eisman
Published online: 20 May 2024
  • 193 Views
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Review

Review Article
Drugs in preclinical and early clinical development for the treatment of Chagas´s disease: the current status
Fernanda Karoline Vieira da Silva Torchelsen, Ana Lia Mazzeti & Vanessa Carla Furtado Mosqueira
Published online: 14 May 2024
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Review

Review Article
Therapeutic potential of cannabidiol (CBD) in the treatment of cardiovascular diseases
Nadia Martinez Naya, Jazmin Kelly, Austin Hogwood, Antonio Abbate & Stefano Toldo
Published online: 09 May 2024
  • 63 Views
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Review

Review Article
From bench to bedside - is there a role of IL-17 drugs in rheumatoid arthritis?
Swetha Byravan, Harini Samarasinghe, Jack Shi Jie Yuan, Syed Haider Tahir, Arumugam Moorthy & Hasan Tahir
Published online: 09 May 2024
  • 28 Views
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Review

Review Article
Frontotemporal dementia: from genetics to therapeutic approaches
Francesca R. Buccellato, Marianna D’Anca, Gianluca Martino Tartaglia, Massimo Del Fabbro & Daniela Galimberti
Published online: 09 May 2024
  • 760 Views
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Open Access

Review

Review Article
Therapies in preclinical and in early clinical development for the treatment of urinary tract infections: from pathogens to therapies
Virginia Fuochi, Salvatore Furnari, Laura Trovato, Maddalena Calvo & Pio Maria Furneri
Published online: 09 May 2024
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Review

Review Article
Emerging therapies for overactive bladder: preclinical, phase I and phase II studies
Samantha Gibson & Pamela Ellsworth
Published online: 09 May 2024
  • 27 Views
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Editorial

Editorial
Will new investigational drugs change the way we treat Charcot-Marie-Tooth disease?
Amedeo De Grado, Chiara Pisciotta, Paola Saveri & Davide Pareyson
Published online: 08 May 2024
  • 216 Views
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Free Access

Special Report

Report
Investigational bispecific antibodies for the treatment of rheumatoid arthritis
Aliki I. Venetsanopoulou, Paraskevi V. Voulgari & Alexandros A. Drosos
Published online: 08 May 2024
  • 63 Views
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Review

Review Article
Prospects of focal adhesion kinase inhibitors as a cancer therapy in preclinical and early phase study
Jiaming Gao, Jingwen Cheng, Wanyu Xie, Ping Zhang, Xuebin Liu, Zaiqi Wang & Baoyuan Zhang
Published online: 08 May 2024
  • 61 Views
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Editorial

Editorial
Lepodisiran, an siRNA targeting lipoprotein(a) for the potential future treatment of cardiovascular disease
P. Mihika S. Fernando, Amanda J. Hooper & John R. Burnett
Published online: 08 May 2024
  • 277 Views
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Free Access

Special Report

Report
The role of phosphodiesterase 9A inhibitors in heart failure
Saam Foroshani, Avrohom Karp, Wilbert S. Aronow & Gregg M. Lanier
Published online: 08 May 2024
  • 21 Views
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Review

Review Article
Investigational farnesoid X receptor agonists for the treatment of primary biliary cholangitis
Prithvi Reddy Akepati & Eric M. Gochanour
Published online: 07 May 2024
  • 55 Views
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Original Research

Article
Safety, tolerability, and pharmacokinetics of the novel RdRp inhibitor SHEN26 against SARS-CoV-2: a randomized, placebo-controlled, double-blind Phase I study in healthy subjects
Cheng Sun, Hao Liu, Ziwei Ouyang, Jie Ding, Qin Zhang, Hongjie Ma, Dandan Xu, Qian Zhang, Renpeng Zhou, Mingming Yang & Wei Hu
Published online: 30 Apr 2024
  • 38 Views
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Review

Review Article
Investigational drugs for the treatment of acromegaly: new agents to transform therapy
Rosa Pirchio, Renata S. Auriemma, Alice Vergura, Rosario Pivonello & Annamaria Colao
Published online: 30 Apr 2024
  • 69 Views
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Editorial

Editorial
Targeting diarrhea-predominant irritable bowel syndrome: hopes or hypes?
Gabrio Bassotti
Published online: 25 Apr 2024
  • 142 Views
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Free Access

Review Article

Review Article
Interleukin antagonists for atopic dermatitis: a new era of therapy
Aikaterini Tsiogka, Eleni Paschou, Dimitra Koumaki, Efstratios Vakirlis & Stamatios Gregoriou
Accepted author version posted online: 24 Apr 2024
  • 175 Views
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Review

Review Article
Sodium/bile acid co-transporter inhibitors currently in preclinical or early clinical development for the treatment of primary biliary cholangitis
Abhishek Gairola, Aaron Wetten & Jessica Dyson
Published online: 24 Apr 2024
  • 42 Views
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Review

Review Article
Investigational agents for autosomal dominant polycystic kidney disease: preclinical and early phase study insights
Irene Capelli, Sarah Lerario, Francesca Ciurli, Gian Marco Berti, Valeria Aiello, Michele Provenzano & Gaetano La Manna
Published online: 21 Apr 2024
  • 173 Views
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Review

Review Article
Experimental and new investigational drugs for the treatment of uterine fibroids
Giulio Evangelisti, Simone Ferrero, Umberto Perrone, Claudio Gustavino, Eugenio Volpi, Alberto Izzotti & Fabio Barra
Published online: 17 Apr 2024
  • 84 Views
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Review

Review Article
Novel carbonic anhydrase inhibitors for the treatment of Helicobacter pylori infection
Claudiu T. Supuran
Published online: 27 Mar 2024
  • 58 Views
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