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Volume 18, Issue 2

Expert Opinion on Investigational Drugs

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Expert Opinion on Investigational Drugs, Volume 18, Issue 2 (2009)

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Expert Opinion on Investigational Drugs, Volume 18, Issue 2 (2009)

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Vol 33, 2024 Vol 32, 2023 Vol 31, 2022 Vol 30, 2021 Vol 29, 2020 Vol 28, 2019 Vol 27, 2018 Vol 26, 2017 Vol 25, 2016 Vol 24, 2015 Vol 23, 2014 Vol 22, 2013 Vol 21, 2012 Vol 20, 2011 Vol 19, 2010 Volume 18, 2009 Vol 17, 2008 Vol 16, 2007 Vol 15, 2006 Vol 14, 2005 Vol 13, 2004 Vol 12, 2003 Vol 11, 2002 Vol 10, 2001 Vol 9, 2000 Vol 8, 1999 Vol 7, 1998 Vol 6, 1997 Vol 5, 1996 Vol 4, 1995 Vol 3, 1994

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Discontinued Drugs Perspective

Article

Discontinued drugs 2007: central and peripheral nervous system drugs

Bjarke Ebert PhD DSc

Pages: 109-123

Published online: 21 Jan 2009

AbstractforDiscontinued drugs 2007: central and peripheral nervous system drugs | Full Text | References | PDF (415.3 KB)

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Reviews

Article

Cannabinoids against pain. Efficacy and strategies to reduce psychoactivity: a clinical perspective

Matthias Karst MD PhD & Sonja Wippermann

Pages: 125-133

Published online: 21 Jan 2009

AbstractforCannabinoids against pain. Efficacy and strategies to reduce psychoactivity: a clinical perspective | Full Text | References | PDF (239.8 KB)

574 Views
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Review

Article

Endothelin receptor antagonism in portal hypertension

Kelly R Pitts PhD

Pages: 135-142

Published online: 24 Dec 2008

AbstractforEndothelin receptor antagonism in portal hypertension | Full Text | References | PDF (261.1 KB)

134 Views
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Article

Experimental therapies in Ewing's sarcoma

Rachael Windsor BSc MBBS MSc, Sandra Strauss, Beatrice Seddon & Jeremy Whelan

Pages: 143-159

Published online: 21 Jan 2009

AbstractforExperimental therapies in Ewing's sarcoma | Full Text | References | PDF (335.5 KB)

167 Views
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Article

Heat shock protein inhibitors and vaccines as new agents in cancer treatment

Eleni M Karapanagiotou, Kostas Syrigos & Muhammad Wasif Saif MD MBBS

Pages: 161-174

Published online: 21 Jan 2009

AbstractforHeat shock protein inhibitors and vaccines as new agents in cancer treatment | Full Text | References | PDF (2 MB)

154 Views
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Article

mTOR-blocking agents in advanced renal cancer: an emerging therapeutic option

Constantin A Dasanu, Bernard A Clark III & Doru T Alexandrescu

Pages: 175-187

Published online: 21 Jan 2009

AbstractformTOR-blocking agents in advanced renal cancer: an emerging therapeutic option | Full Text | References | PDF (426.9 KB)

134 Views
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Drug Evaluations

Article

A review and update of the current status of the vasculature-disabling agent combretastatin-A4 phosphate (CA4P)

Dietmar W Siemann PhD, David J Chaplin PhD & Patricia A Walicke MD PhD

Pages: 189-197

Published online: 21 Jan 2009

AbstractforA review and update of the current status of the vasculature-disabling agent combretastatin-A4 phosphate (CA4P) | Full Text | References | PDF (2.3 MB)

541 Views
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Drug Evaluation

Article

Apricitabine – a novel nucleoside reverse transcriptase inhibitor for the treatment of HIV infection that is refractory to existing drugs

Susan Cox PhD & Justine Southby PhD

Pages: 199-209

Published online: 15 Dec 2008

AbstractforApricitabine – a novel nucleoside reverse transcriptase inhibitor for the treatment of HIV infection that is refractory to existing drugs | Full Text | References | PDF (350.3 KB)

59 Views
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Article

An evaluation of the cyclophilin inhibitor Debio 025 and its potential as a treatment for chronic hepatitis C

Raf Crabbé, Grégoire Vuagniaux, Jean-Maurice Dumont, Valérie Nicolas-Métral, Judith Marfurt & Laura Novaroli

Pages: 211-220

Published online: 15 Dec 2008

AbstractforAn evaluation of the cyclophilin inhibitor Debio 025 and its potential as a treatment for chronic hepatitis C | Full Text | References | PDF (361.4 KB)

274 Views
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Article

Eslicarbazepine acetate: a new option for the treatment of focal epilepsy

Joaquim Ferreira & Tiago Mestre

Pages: 221-229

Published online: 15 Dec 2008

AbstractforEslicarbazepine acetate: a new option for the treatment of focal epilepsy | Full Text | References | PDF (277 KB)

121 Views
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Article

Senicapoc (ICA-17043): a potential therapy for the prevention and treatment of hemolysis-associated complications in sickle cell anemia

Kenneth I Ataga MBBS & Jonathan Stocker PhD

Pages: 231-239

Published online: 21 Jan 2009

AbstractforSenicapoc (ICA-17043): a potential therapy for the prevention and treatment of hemolysis-associated complications in sickle cell anemia | Full Text | References | PDF (356.1 KB)

640 Views
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Key Paper Evaluation

Article

HIF-1α inhibition as a novel mechanism of cardiac glycosides in cancer therapeutics

Evaluation of: Zhang H, Qian DZ, Tan YS, et al. Digoxin and other cardiac glycosides inhibit HIF-1α synthesis and block tumor growth. Proc Natl Acad Sci USA 2008;105:19579-86

Jianqing Lin & Michael A Carducci

Pages: 241-243

Published online: 21 Jan 2009

AbstractforHIF-1α inhibition as a novel mechanism of cardiac glycosides in cancer therapeutics | Full Text | References | PDF (211.4 KB)

143 Views
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