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Volume 20, Issue 4

Expert Opinion on Investigational Drugs

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Expert Opinion on Investigational Drugs, Volume 20, Issue 4 (2011)

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Expert Opinion on Investigational Drugs, Volume 20, Issue 4 (2011)

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Vol 33, 2024 Vol 32, 2023 Vol 31, 2022 Vol 30, 2021 Vol 29, 2020 Vol 28, 2019 Vol 27, 2018 Vol 26, 2017 Vol 25, 2016 Vol 24, 2015 Vol 23, 2014 Vol 22, 2013 Vol 21, 2012 Volume 20, 2011 Vol 19, 2010 Vol 18, 2009 Vol 17, 2008 Vol 16, 2007 Vol 15, 2006 Vol 14, 2005 Vol 13, 2004 Vol 12, 2003 Vol 11, 2002 Vol 10, 2001 Vol 9, 2000 Vol 8, 1999 Vol 7, 1998 Vol 6, 1997 Vol 5, 1996 Vol 4, 1995 Vol 3, 1994

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Original Research

Article

Naloxone as part of a prolonged release oxycodone/naloxone combination reduces oxycodone-induced slowing of gastrointestinal transit in healthy volunteers

Kevin Smith PhD, Michael Hopp, Gill Mundin, Simon Bond, Paul Bailey, Jo Woodward, Karuppan Palaniappan, Ann Church, Marie Limb & Alyson Connor

Pages: 427-439

Published online: 14 Mar 2011

AbstractforNaloxone as part of a prolonged release oxycodone/naloxone combination reduces oxycodone-induced slowing of gastrointestinal transit in healthy volunteers | Full Text | References | PDF (517.7 KB)

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Reviews

Article

Update on new drugs in small cell lung cancer

Leora Horn, Emily Louise Castellanos & David H Johnson

Pages: 441-455

Published online: 14 Mar 2011

AbstractforUpdate on new drugs in small cell lung cancer | Full Text | References | PDF (252 KB)

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Article

Combined neutral endopeptidase inhibitors

Florim Cuculi & Paul Erne

Pages: 457-463

Published online: 15 Feb 2011

AbstractforCombined neutral endopeptidase inhibitors | Full Text | References | PDF (332.2 KB)

313 Views
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Article

Epigenetic regulation in myelodysplastic syndromes: implications for therapy

Ernesto Vigna, Anna Grazia Recchia, Antonio Madeo, Massimo Gentile, Sabrina Bossio, Carla Mazzone, Eugenio Lucia, Lucio Morabito, Vincenzo Gigliotti, Laura De Stefano, Nadia Caruso, Pasquale Servillo, Stefania Franzese, Filippo Fimognari, Maria Grazia Bisconte, Carlo Gentile & Fortunato Morabito

Pages: 465-493

Published online: 08 Mar 2011

AbstractforEpigenetic regulation in myelodysplastic syndromes: implications for therapy | Full Text | References | PDF (2.9 MB)

601 Views
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Article

Investigational factor Xa inhibitors for thrombosis and acute coronary syndromes

Erica Romualdi MD & Walter Ageno MD

Pages: 495-505

Published online: 09 Mar 2011

AbstractforInvestigational factor Xa inhibitors for thrombosis and acute coronary syndromes | Full Text | References | PDF (207.8 KB)

388 Views
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Article

New phosphatidylinositol 3-kinase inhibitors for cancer

Daniel W Bowles MD & Antonio Jimeno MD PhD

Pages: 507-518

Published online: 14 Mar 2011

AbstractforNew phosphatidylinositol 3-kinase inhibitors for cancer | Full Text | References | PDF (331.5 KB)

472 Views
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Article

Corticotropin releasing factor receptor antagonists for major depressive disorder

Marcelo Paez-Pereda, Felix Hausch & Florian Holsboer

Pages: 519-535

Published online: 14 Mar 2011

AbstractforCorticotropin releasing factor receptor antagonists for major depressive disorder | Full Text | References | PDF (424.6 KB)

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Drug Evaluations

Article

S/GSK1349572, a new integrase inhibitor for the treatment of HIV: promises and challenges

Johannes Carl Christoph Lenz & Jürgen Kurt Rockstroh

Pages: 537-548

Published online: 08 Mar 2011

AbstractforS/GSK1349572, a new integrase inhibitor for the treatment of HIV: promises and challenges | Full Text | References | PDF (503 KB)

373 Views
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Article

Lixisenatide for type 2 diabetes mellitus

Mikkel Christensen MD, Filip K Knop, Tina Vilsbøll & Jens J Holst

Pages: 549-557

Published online: 11 Mar 2011

AbstractforLixisenatide for type 2 diabetes mellitus | Full Text | References | PDF (218.8 KB)

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Article

Antiviral hyperactivation-limiting therapeutics as a novel class for the treatment of HIV/AIDS: focus on VS411

Alessia Uglietti MD & Renato Maserati MD

Pages: 559-565

Published online: 11 Mar 2011

AbstractforAntiviral hyperactivation-limiting therapeutics as a novel class for the treatment of HIV/AIDS: focus on VS411 | Full Text | References | PDF (331.1 KB)

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Article

Riociguat for the treatment of pulmonary hypertension

Ralph T Schermuly, Wiebke Janssen, Norbert Weissmann, Johannes-Peter Stasch, Friedrich Grimminger & Hossein Ardeschir Ghofrani

Pages: 567-576

Published online: 11 Mar 2011

AbstractforRiociguat for the treatment of pulmonary hypertension | Full Text | References | PDF (382.4 KB)

1239 Views
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Article

Brivanib alaninate for cancer

Ivan Diaz-Padilla MD & Lillian L Siu

Pages: 577-586

Published online: 11 Mar 2011

AbstractforBrivanib alaninate for cancer | Full Text | References | PDF (307.5 KB)

388 Views
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Key Paper Evaluation

Article

A new approach to Parkinson's disease: inhibition of leucine-rich repeat kinase-2

Evaluation of: Lee BD, Shin J-H, VanKampen J, et al. Inhibitors of leucine-rich repeat kinase-2 protect against models of Parkinson's disease. Nat Med 2010;16:998-1000

Sheila A Doggrell PhD DSc

Pages: 587-590

Published online: 12 Feb 2011

AbstractforA new approach to Parkinson's disease: inhibition of leucine-rich repeat kinase-2 | Full Text | References | PDF (170.1 KB)

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