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Volume 24, Issue 9

Expert Opinion on Investigational Drugs

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Expert Opinion on Investigational Drugs, Volume 24, Issue 9 (2015)

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Expert Opinion on Investigational Drugs, Volume 24, Issue 9 (2015)

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Editorial

Advanced neuroprotection for brain ischemia: an alternative approach to minimize stroke damage

Maria Irene Ayuso & Joan Montaner

Pages: 1137-1142

Published online: 03 Jul 2015

AbstractforAdvanced neuroprotection for brain ischemia: an alternative approach to minimize stroke damage | Full Text | References | PDF (264.6 KB)

2078 Views
15 CrossRef citations
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Free Access

Review

An overview of angiogenesis inhibitors in Phase II studies for non-small-cell lung cancer

Sara Pilotto, Silvia Novello, Umberto Peretti, Stefania Kinspergher, Ludovica Ciuffreda, Michele Milella, Luisa Carbognin, Tiziana Vavalà, Roberto Ferrara, Mario Caccese, Giampaolo Tortora & Emilio Bria

Pages: 1143-1161

Published online: 12 Jun 2015

AbstractforAn overview of angiogenesis inhibitors in Phase II studies for non-small-cell lung cancer | Full Text | References | PDF (512.1 KB)

294 Views
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An overview of early investigational therapies for chemoresistant ovarian cancer

Claudia Marchetti (Clinical Research Fellow in Gynecological Oncology) MD, Jonathan A Ledermann (Professor of Medical Oncology UCL Cancer Institute, Clinical Director, UCL Cancer Institute & Director) BSc MD FRCP & Pierluigi Benedetti Panici MD

Pages: 1163-1183

Published online: 24 Jul 2015

AbstractforAn overview of early investigational therapies for chemoresistant ovarian cancer | Full Text | References | PDF (474.4 KB)

490 Views
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Role and mechanisms of resistance of epidermal growth factor receptor antagonists in the treatment of colorectal cancer

Karim Rihawi MD, Riccardo Giampieri MD, Mario Scartozzi MD, Valeria Pusceddu MD, Marta Bonotto MD, Gianpiero Fasola MD, Stefano Cascinu MD & Giuseppe Aprile MD

Pages: 1185-1198

Published online: 04 Jun 2015

AbstractforRole and mechanisms of resistance of epidermal growth factor receptor antagonists in the treatment of colorectal cancer | Full Text | References | PDF (499.7 KB)

293 Views
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An overview of experimental and early investigational therapies for the treatment of polycystic kidney disease

Domenico Santoro (Aggregate Professor) MD, Vincenzo Pellicanò, Luca Visconti, Gianluca Trifirò, Michele Buemi & Valeria Cernaro

Pages: 1199-1218

Published online: 30 Jun 2015

AbstractforAn overview of experimental and early investigational therapies for the treatment of polycystic kidney disease | Full Text | References | PDF (552 KB)

521 Views
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Investigational reverse transcriptase inhibitors for the treatment of HIV

Theodore J Cory (Assistant Professor) , Narasimha M Midde (Postdoctoral Fellow) , PSS Rao (Postdoctoral Fellow) & Santosh Kumar (Associate Professor)

Pages: 1219-1228

Published online: 19 Jun 2015

AbstractforInvestigational reverse transcriptase inhibitors for the treatment of HIV | Full Text | References | PDF (424.3 KB)

217 Views
9 CrossRef citations
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Current drugs in early development for treating hepatitis C virus-related hepatic fibrosis

Jerzy Jaroszewicz (Associate Professor) , Marta Flisiak-Jackiewicz, Dariusz Lebensztejn (Professor) & Robert Flisiak (Professor)

Pages: 1229-1239

Published online: 30 Jun 2015

AbstractforCurrent drugs in early development for treating hepatitis C virus-related hepatic fibrosis | Full Text | References | PDF (271 KB)

296 Views
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Discontinued Drug Perspective

Discontinued drug therapies to treat diabetes in 2014

Jerry R Colca

Pages: 1241-1245

Published online: 17 Jun 2015

AbstractforDiscontinued drug therapies to treat diabetes in 2014 | Full Text | References | PDF (160.3 KB)

262 Views
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Drug Evaluation

Basimglurant for treatment of major depressive disorder: a novel negative allosteric modulator of metabotropic glutamate receptor 5

Kjell Fuxe (Professor) & Dasiel O Borroto-Escuela PhD

Pages: 1247-1260

Published online: 29 Jul 2015

AbstractforBasimglurant for treatment of major depressive disorder: a novel negative allosteric modulator of metabotropic glutamate receptor 5 | Full Text | References | PDF (895.1 KB)

445 Views
31 CrossRef citations
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Focus on ceftazidime-avibactam for optimizing outcomes in complicated intra-abdominal and urinary tract infections

David P Nicolau PharmD FCCP FIDSA

Pages: 1261-1273

Published online: 06 Jul 2015

AbstractforFocus on ceftazidime-avibactam for optimizing outcomes in complicated intra-abdominal and urinary tract infections | Full Text | References | PDF (419.2 KB)

602 Views
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Oxaliplatin for the treatment of ovarian cancer

Stefano Bogliolo MD, Chiara Cassani MD, Barbara Gardella MD, Valentina Musacchi MD, Luciana Babilonti MD, Pier-Luigi Venturini MD, Simone Ferrero MD & Arsenio Spinillo MD

Pages: 1275-1286

Published online: 30 Jun 2015

AbstractforOxaliplatin for the treatment of ovarian cancer | Full Text | References | PDF (328.6 KB)

659 Views
20 CrossRef citations
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Ixazomib for the treatment of multiple myeloma

Massimo Gentile, Massimo Offidani, Ernesto Vigna, Laura Corvatta, Anna Grazia Recchia, Lucio Morabito, Fortunato Morabito & Silvia Gentili

Pages: 1287-1298

Published online: 03 Jul 2015

AbstractforIxazomib for the treatment of multiple myeloma | Full Text | References | PDF (407.1 KB)

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