Expert Opinion on Investigational Drugs, Volume 26, Issue 2 (2017)

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Expert Opinion on Investigational Drugs, Volume 26, Issue 2 (2017)

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Editorial

Editorial
Thoughts on investigational hedgehog pathway inhibitors for the treatment of cancer
Tarkan Jäger, Matthias Ocker, Tobias Kiesslich, Elen Neureiter & Daniel Neureiter
Pages: 133-136
Published online: 27 Dec 2016
First Page PreviewforThoughts on investigational hedgehog pathway inhibitors for the treatment of cancer | Full Text | References | PDF (531.7 KB)
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Editorial
PCSK9 inhibitors in sepsis: a new potential indication?
Amir Abbas Momtazi, Maciej Banach & Amirhossein Sahebkar
Pages: 137-139
Published online: 21 Dec 2016
First Page PreviewforPCSK9 inhibitors in sepsis: a new potential indication? | Full Text | References | PDF (303.9 KB)
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Review

Review
Recent early clinical drug development for acute kidney injury
Kevin M. Gallagher, Stephen O’neill, Ewen M Harrison, James A Ross, Stephen J Wigmore & Jeremy Hughes
Pages: 141-154
Published online: 27 Dec 2016
AbstractforRecent early clinical drug development for acute kidney injury | Full Text | References | PDF (1.5 MB)
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Review
Targeting delta opioid receptors for pain treatment: drugs in phase I and II clinical development
Viola Spahn & Christoph Stein
Pages: 155-160
Published online: 02 Jan 2017
AbstractforTargeting delta opioid receptors for pain treatment: drugs in phase I and II clinical development | Full Text | References | PDF (823.2 KB)
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Review
Long acting muscarinic antagonists for the treatment of chronic obstructive pulmonary disease: a review of current and developing drugs
Mark A. Mastrodicasa, Christopher A. Droege, Aaron M. Mulhall, Neil E. Ernst, Ralph J. Panos & Muhammad A. Zafar
Pages: 161-174
Published online: 09 Jan 2017
AbstractforLong acting muscarinic antagonists for the treatment of chronic obstructive pulmonary disease: a review of current and developing drugs | Full Text | References | PDF (1.2 MB)
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Review
Investigational agents for the management of Huntington’s disease
Thomas Müller
Pages: 175-185
Published online: 16 Dec 2016
AbstractforInvestigational agents for the management of Huntington’s disease | Full Text | References | PDF (851.8 KB)
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Review
Glucocorticoid-targeted therapies for the treatment of rheumatoid arthritis
Cindy Strehl, Marlies C. van der Goes, Johannes W.J. Bijlsma, Johannes W. G. Jacobs & Frank Buttgereit
Pages: 187-195
Published online: 03 Jan 2017
AbstractforGlucocorticoid-targeted therapies for the treatment of rheumatoid arthritis | Full Text | References | PDF (1 MB)
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Review
Current treatment options and investigational drugs for Waldenstrom’s Macroglobulinemia
Maria Gavriatopoulou, Evangelos Terpos, Efstathios Kastritis & Meletios A. Dimopoulos
Pages: 197-205
Published online: 03 Jan 2017
AbstractforCurrent treatment options and investigational drugs for Waldenstrom’s Macroglobulinemia | Full Text | References | PDF (705.3 KB)
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Review
Do CDK4/6 inhibitors have potential as targeted therapeutics for squamous cell cancers?
Nene N. Kalu & Faye M. Johnson
Pages: 207-217
Published online: 01 Jan 2017
AbstractforDo CDK4/6 inhibitors have potential as targeted therapeutics for squamous cell cancers? | Full Text | References | PDF (1.1 MB)
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Perspective

Article
Discontinued drug therapies to treat diabetes in 2015
Maka S. Hedrington & Stephen N. Davis
Pages: 219-225
Published online: 26 Dec 2016
AbstractforDiscontinued drug therapies to treat diabetes in 2015 | Full Text | References | PDF (561.8 KB)
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Drug Evaluation

Article
Lasmiditan for the treatment of migraine
Matilde Capi, Fernando de Andrés, Luana Lionetto, Giovanna Gentile, Fabiola Cipolla, Andrea Negro, Marina Borro, Paolo Martelletti & Martina Curto
Pages: 227-234
Published online: 23 Jan 2017
AbstractforLasmiditan for the treatment of migraine | Full Text | References | PDF (964.4 KB)
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Article
Letermovir for the management of cytomegalovirus infection
Lyndsey J. Bowman, Jennifer Iuppa Melaragno & Daniel C. Brennan
Pages: 235-241
Published online: 28 Dec 2016
AbstractforLetermovir for the management of cytomegalovirus infection | Full Text | References | PDF (672.8 KB)
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Article
The potential utility of tildrakizumab: an interleukin-23 inhibitor for the treatment of psoriasis
Zenas Z. N. Yiu & Richard B. Warren
Pages: 243-249
Published online: 01 Jan 2017
AbstractforThe potential utility of tildrakizumab: an interleukin-23 inhibitor for the treatment of psoriasis | Full Text | References | PDF (783.6 KB)
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Article
Evaluating bempedoic acid for the treatment of hyperlipidaemia
Peter Penson, Mary McGowan & Maciej Banach
Pages: 251-259
Published online: 17 Jan 2017
AbstractforEvaluating bempedoic acid for the treatment of hyperlipidaemia | Full Text | References | PDF (918.4 KB)
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Erratum

Correction
Erratum
Page: 261
Published online: 05 Jan 2017
CitationforErratum | Full Text | PDF (71.7 KB)
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Corrigendum

Correction
Corrigendum
Page: 263
Published online: 23 Jan 2017
CitationforCorrigendum | Full Text | PDF (82.2 KB)
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