Expert Opinion on Investigational Drugs, Volume 26, Issue 5 (2017)

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Expert Opinion on Investigational Drugs, Volume 26, Issue 5 (2017)

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Editorial

Editorial
Therapeutic targeting of isocitrate dehydrogenase mutant AML
Prajwal Boddu & Gautam Borthakur
Pages: 525-530
Published online: 19 Apr 2017
First Page PreviewforTherapeutic targeting of isocitrate dehydrogenase mutant AML | Full Text | References | PDF (651.3 KB)
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Free Access

Review

Review
Perspectives of HER2-targeting in gastric and esophageal cancer
James N Gerson, Sam Skariah, Crystal S. Denlinger & Igor Astsaturov
Pages: 531-540
Published online: 24 Apr 2017
AbstractforPerspectives of HER2-targeting in gastric and esophageal cancer | Full Text | References | PDF (950.6 KB)
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Review
Heat shock protein antagonists in early stage clinical trials for NSCLC
Lizza E.L. Hendriks & Anne-Marie C. Dingemans
Pages: 541-550
Published online: 08 Mar 2017
AbstractforHeat shock protein antagonists in early stage clinical trials for NSCLC | Full Text | References | PDF (823.2 KB)
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Open Access
Review
Investigational drugs targeting fibroblast growth factor receptor in the treatment of non-small cell lung cancer
Erika Rijavec, Carlo Genova, Giulia Barletta, Federica Biello, Giovanni Rossi, Marco Tagliamento, Maria Giovanna Dal Bello, Simona Coco, Irene Vanni, Simona Boccardo, Angela Alama & Francesco Grossi
Pages: 551-561
Published online: 13 Apr 2017
AbstractforInvestigational drugs targeting fibroblast growth factor receptor in the treatment of non-small cell lung cancer | Full Text | References | PDF (917.4 KB)
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Review
Pharmacotherapeutic agents in the treatment of methamphetamine dependence
Kirsten C. Morley, Jennifer L. Cornish, Alon Faingold, Katie Wood & Paul S. Haber
Pages: 563-578
Published online: 07 Apr 2017
AbstractforPharmacotherapeutic agents in the treatment of methamphetamine dependence | Full Text | References | PDF (1.1 MB)
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Review
Preclinical to phase II amyloid beta (Aβ) peptide modulators under investigation for Alzheimer’s disease
Chris G. Parsons & Gerhard Rammes
Pages: 579-592
Published online: 24 Apr 2017
AbstractforPreclinical to phase II amyloid beta (Aβ) peptide modulators under investigation for Alzheimer’s disease | Full Text | References | PDF (1.1 MB)
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Review
PPAR-α agonists are still on the rise: an update on clinical and experimental findings
Nicola Ferri, Alberto Corsini, Cesare Sirtori & Massimiliano Ruscica
Pages: 593-602
Published online: 11 Apr 2017
AbstractforPPAR-α agonists are still on the rise: an update on clinical and experimental findings | Full Text | References | PDF (1.1 MB)
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Review
Investigational therapies for hypercholesterolemia
Gerald H. Tomkin & Daphne Owens
Pages: 603-617
Published online: 13 Apr 2017
AbstractforInvestigational therapies for hypercholesterolemia | Full Text | References | PDF (1.3 MB)
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Original Research

Article
A randomized, double-blind, single-dose, two-arm, parallel study comparing pharmacokinetics, immunogenicity and tolerability of branded adalimumab and its biosimilar LBAL in healthy male volunteers
Kyoung Ryun Park, Hyewon Chung, Sung Mo Yang, SeungHwan Lee, Seo Hyun Yoon, Joo-Youn Cho, In-Jin Jang & Kyung-Sang Yu
Pages: 619-624
Published online: 23 Mar 2017
AbstractforA randomized, double-blind, single-dose, two-arm, parallel study comparing pharmacokinetics, immunogenicity and tolerability of branded adalimumab and its biosimilar LBAL in healthy male volunteers | Full Text | References | PDF (752.6 KB)
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Drug Evaluation

Article
Duvelisib: a phosphoinositide-3 kinase δ/γ inhibitor for chronic lymphocytic leukemia
Hima V. Vangapandu, Nitin Jain & Varsha Gandhi
Pages: 625-632
Published online: 13 Apr 2017
AbstractforDuvelisib: a phosphoinositide-3 kinase δ/γ inhibitor for chronic lymphocytic leukemia | Full Text | References | PDF (757.8 KB) | Supplemental
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Article
Lenalidomide in the treatment of chronic lymphocytic leukemia
Gilad Itchaki & Jennifer R. Brown
Pages: 633-650
Published online: 17 Apr 2017
AbstractforLenalidomide in the treatment of chronic lymphocytic leukemia | Full Text | References | PDF (1.5 MB)
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Article
Potential beneficial effects of sacubitril-valsartan in renal disease: a new field for a new drug
Guillermo Gervasini & Nicolas Roberto Robles
Pages: 651-659
Published online: 21 Apr 2017
AbstractforPotential beneficial effects of sacubitril-valsartan in renal disease: a new field for a new drug | Full Text | References | PDF (1 MB)
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