Expert Opinion on Investigational Drugs, Volume 26, Issue 8 (2017)

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Expert Opinion on Investigational Drugs, Volume 26, Issue 8 (2017)

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Editorial

Editorial
Do STAT3 inhibitors have potential in the future for cancer therapy?
Andrea L.A. Wong, Jayshree L. Hirpara, Shazib Pervaiz, Jie-Qing Eu, Gautam Sethi & Boon-Cher Goh
Pages: 883-887
Published online: 17 Jul 2017
First Page PreviewforDo STAT3 inhibitors have potential in the future for cancer therapy? | Full Text | References | PDF (500.5 KB)
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Original Research

Article
A randomized, single-blind, Phase I trial (INVICTAN-1) assessing the bioequivalence and safety of BI 695502, a bevacizumab biosimilar candidate, in healthy subjects
Willem Hettema, Christopher Wynne, Benjamin Lang, Mario Altendorfer, Niklas Czeloth, Ragna Lohmann, Sandeep Athalye & Dorothee Schliephake
Pages: 889-896
Published online: 12 Jul 2017
AbstractforA randomized, single-blind, Phase I trial (INVICTAN-1) assessing the bioequivalence and safety of BI 695502, a bevacizumab biosimilar candidate, in healthy subjects | Full Text | References | PDF (1.2 MB)
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Review

Review
Investigational antiarrhythmic agents: promising drugs in early clinical development
Jordi Heijman, Shokoufeh Ghezelbash & Dobromir Dobrev
Pages: 897-907
Published online: 20 Jul 2017
AbstractforInvestigational antiarrhythmic agents: promising drugs in early clinical development | Full Text | References | PDF (1 MB)
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Review
Bruton’s tyrosine kinase inhibitors in B-cell lymphoma: current experience and future perspectives
T. Seiler & M. Dreyling
Pages: 909-915
Published online: 10 Jul 2017
AbstractforBruton’s tyrosine kinase inhibitors in B-cell lymphoma: current experience and future perspectives | Full Text | References | PDF (736.7 KB)
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Review
Experimental and early investigational drugs for androgenetic alopecia
Hongwei Guo, Wendi Victor Gao, Hiromi Endo & Kevin John McElwee
Pages: 917-932
Published online: 12 Jul 2017
AbstractforExperimental and early investigational drugs for androgenetic alopecia | Full Text | References | PDF (1.3 MB)
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Review
Promising investigational drug candidates in phase I and phase II clinical trials for mesothelioma
Alice Guazzelli, Emyr Bakker, Kun Tian, Constantinos Demonacos, Marija Krstic-Demonacos & Luciano Mutti
Pages: 933-944
Published online: 12 Jul 2017
AbstractforPromising investigational drug candidates in phase I and phase II clinical trials for mesothelioma | Full Text | References | PDF (1.2 MB)
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Review
Investigational drugs in development for focal segmental glomerulosclerosis
Howard Trachtman
Pages: 945-952
Published online: 14 Jul 2017
AbstractforInvestigational drugs in development for focal segmental glomerulosclerosis | Full Text | References | PDF (651.5 KB)
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Review
Investigational therapies for the treatment of narcolepsy
Stefano de Biase, Annacarmen Nilo, Gian Luigi Gigli & Mariarosaria Valente
Pages: 953-963
Published online: 20 Jul 2017
AbstractforInvestigational therapies for the treatment of narcolepsy | Full Text | References | PDF (788.7 KB)
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Drug Evaluation

Article
Entinostat for the treatment of breast cancer
Dario Trapani, Angela Esposito, Carmen Criscitiello, Luca Mazzarella, Marzia Locatelli, Ida Minchella, Saverio Minucci & Giuseppe Curigliano
Pages: 965-971
Published online: 24 Jul 2017
AbstractforEntinostat for the treatment of breast cancer | Full Text | References | PDF (638.8 KB)
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Article
Selumetinib for the treatment of non-small cell lung cancer
Francesca Casaluce, Assunta Sgambato, Paolo Maione, Paola Claudia Sacco, Giuseppe Santabarbara & Cesare Gridelli
Pages: 973-984
Published online: 12 Jul 2017
AbstractforSelumetinib for the treatment of non-small cell lung cancer | Full Text | References | PDF (857.3 KB)
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Article
Lurasidone for the treatment of irritability and anger in autism spectrum disorders
Lynn McClellan, Kelli C. Dominick, Ernest V. Pedapati, Logan K. Wink & Craig A. Erickson
Pages: 985-989
Published online: 24 Jul 2017
AbstractforLurasidone for the treatment of irritability and anger in autism spectrum disorders | Full Text | References | PDF (408.9 KB)
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Article
Alicaforsen for the treatment of inflammatory bowel disease
Vipul Jairath, Reena Khanna & Brian G. Feagan
Pages: 991-997
Published online: 06 Jul 2017
AbstractforAlicaforsen for the treatment of inflammatory bowel disease | Full Text | References | PDF (573 KB)
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