Expert Opinion on Investigational Drugs, Volume 32, Issue 2 (2023)

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Expert Opinion on Investigational Drugs, Volume 32, Issue 2 (2023)

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Drug Evaluation

Article
Lecanemab (BAN2401): an anti–beta-amyloid monoclonal antibody for the treatment of Alzheimer disease
Grace E. Vitek, Boris Decourt & Marwan N. Sabbagh
Pages: 89-94
Published online: 28 Feb 2023
AbstractforLecanemab (BAN2401): an anti–beta-amyloid monoclonal antibody for the treatment of Alzheimer disease | Full Text | References | PDF (259 KB) | EPUB
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Special Report

Article
Experimental treatments in clinical trials for diabetic foot ulcers: wound healers in the pipeline
Brandon J Sumpio, Ikram Mezghani, Enya Wang, Zhuqing Li, Eleftheria-Angeliki Valsami, Georgios Theocharidis & Aristidis Veves
Pages: 95-99
Published online: 21 Feb 2023
AbstractforExperimental treatments in clinical trials for diabetic foot ulcers: wound healers in the pipeline | Full Text | References | PDF (292.2 KB) | EPUB
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Article
Multiple initiatives to conquer KRAS G12C inhibitor resistance from the perspective of clinical therapy
Junmin Zhang, Juanhong Zhang, Elaine Lai-Han Leung & Xiao-Jun Yao
Pages: 101-106
Published online: 15 Feb 2023
AbstractforMultiple initiatives to conquer KRAS G12C inhibitor resistance from the perspective of clinical therapy | Full Text | References | PDF (1.9 MB) | EPUB
  • 330 Views
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Review

Review
Antibody therapies for the treatment of acute myeloid leukemia: exploring current and emerging therapeutic targets
Joshua W. Morse, Margarita Rios, John Ye, Adan Rios, Cheng Cheng Zhang, Naval G. Daver, Courtney D. DiNardo, Ningyan Zhang & Zhiqiang An
Pages: 107-125
Published online: 26 Feb 2023
AbstractforAntibody therapies for the treatment of acute myeloid leukemia: exploring current and emerging therapeutic targets | Full Text | References | PDF (3.6 MB) | EPUB
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Review
Investigational drugs for HIV: trends, opportunities and key players
Ronald J. Overmars, Zoë Krullaars & Thibault Mesplède
Pages: 127-139
Published online: 15 Feb 2023
AbstractforInvestigational drugs for HIV: trends, opportunities and key players | Full Text | References | PDF (2.4 MB) | EPUB
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Review
Emerging clinical investigational drugs for the treatment of amyotrophic lateral sclerosis
Loreto Martinez-Gonzalez & Ana Martinez
Pages: 141-160
Published online: 16 Feb 2023
AbstractforEmerging clinical investigational drugs for the treatment of amyotrophic lateral sclerosis | Full Text | References | PDF (4.8 MB) | EPUB
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Original Research

Article
Pharmacokinetics, pharmacodynamics, safety, and immunogenicity of Gerilimzumab (GB224), a recombinant humanized interleukin-6 monoclonal antibody, in healthy Chinese adults: A randomized controlled dose–escalation study
Diqin Yan, Suping Niu, Dingyuan Hu, Wenliang Dong, Yunjuan Sun, Qian Wang, Simin Wang, Qun Gu, Gang Liu, Jiaxue Wang, Liming Chen, Jie Lv, Qingshan Zheng, Haifeng Song & Yi Fang
Pages: 161-170
Published online: 20 Feb 2023
AbstractforPharmacokinetics, pharmacodynamics, safety, and immunogenicity of Gerilimzumab (GB224), a recombinant humanized interleukin-6 monoclonal antibody, in healthy Chinese adults: A randomized controlled dose–escalation study | Full Text | References | PDF (1.9 MB) | EPUB
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Article
Collocation of metformin and dipeptidyl peptidase-4 inhibitor is associated with increased risk of diabetes-related vascular dementia: A single hospital study in Northern Taiwan
I-Shiang Tzeng & Tsung-Han Hsieh
Pages: 171-176
Published online: 17 Feb 2023
AbstractforCollocation of metformin and dipeptidyl peptidase-4 inhibitor is associated with increased risk of diabetes-related vascular dementia: A single hospital study in Northern Taiwan | Full Text | References | PDF (886.1 KB) | EPUB
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