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Volume 10, Issue 3

Expert Opinion on Drug Metabolism & Toxicology

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Expert Opinion on Drug Metabolism & Toxicology, Volume 10, Issue 3 (2014)

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Expert Opinion on Drug Metabolism & Toxicology, Volume 10, Issue 3 (2014)

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Original Research

Article

Pharmacokinetic interaction between febuxostat and morin in rats

Kapendra Sahu, Anees A Siddiqui, Mohammad Shaharyar & Sachin Malik

Pages: 307-312

Published online: 08 Feb 2014

AbstractforPharmacokinetic interaction between febuxostat and morin in rats | Full Text | References | PDF (401.8 KB)

217 Views
8 CrossRef citations
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Article

The effect of the Pheroid delivery system on the in vitro metabolism and in vivo pharmacokinetics of artemisone

Lizette Grobler MSc, Anne Grobler PhD, Richard Haynes (Professor) PhD, Collen Masimirembwa PhD, Roslyn Thelingwani PhD, Paul Steenkamp (Professor) PhD & Hendrik Stefanus Steyn (Professor) PhD

Pages: 313-325

Published online: 10 Feb 2014

AbstractforThe effect of the Pheroid delivery system on the in vitro metabolism and in vivo pharmacokinetics of artemisone | Full Text | References | PDF (891.3 KB)

119 Views
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Reviews

Review Article

Modulation of cardiac cytochrome P450 in patients with heart failure

Nadia Aspromonte MD FESC FACC, Francesco Monitillo MD, Agata Puzzovivo MD, Roberto Valle MD, Pasquale Caldarola MD & Massimo Iacoviello MD

Pages: 327-339

Published online: 03 Jan 2014

AbstractforModulation of cardiac cytochrome P450 in patients with heart failure | Full Text | References | PDF (440.8 KB)

346 Views
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Review Article

Implications of pharmacogenetics for the therapeutic use of antiepileptic drugs

Chiara Piana, Natalicia de Jesus Antunes & Oscar Della Pasqua

Pages: 341-358

Published online: 25 Jan 2014

AbstractforImplications of pharmacogenetics for the therapeutic use of antiepileptic drugs | Full Text | References | PDF (703.2 KB)

406 Views
15 CrossRef citations
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Review Article

Drug interactions with phytotherapeutics in oncology

Walter Emil Haefeli MD & Alexandra Carls

Pages: 359-377

Published online: 06 Jan 2014

AbstractforDrug interactions with phytotherapeutics in oncology | Full Text | References | PDF (469.6 KB)

993 Views
53 CrossRef citations
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Review Article

The role of drug metabolizing enzymes in clearance

Li Di (Associate Research Fellow)

Pages: 379-393

Published online: 07 Jan 2014

AbstractforThe role of drug metabolizing enzymes in clearance | Full Text | References | PDF (754.8 KB)

1772 Views
138 CrossRef citations
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Review Article

Solute carrier transporter and drug-related nephrotoxicity: the impact of proximal tubule cell models for preclinical research

Pascale Fisel, Olga Renner, Anne T Nies, Matthias Schwab (Professor) & Elke Schaeffeler

Pages: 395-408

Published online: 08 Jan 2014

AbstractforSolute carrier transporter and drug-related nephrotoxicity: the impact of proximal tubule cell models for preclinical research | Full Text | References | PDF (462.1 KB)

670 Views
36 CrossRef citations
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Review Article

Clinical implications of irregular ADMET properties with levodopa and other antiparkinson's drugs

Livia Dézsi MD & László Vécsei MD PhD DSc

Pages: 409-424

Published online: 17 Jan 2014

AbstractforClinical implications of irregular ADMET properties with levodopa and other antiparkinson's drugs | Full Text | References | PDF (512.2 KB)

224 Views
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Review Article

Cytochrome P450 enzyme regulation by glucocorticoids and consequences in terms of drug interaction

Petra Matoulková (Assistant Professor (Research Fellow)) , Petr Pávek (Associate Professor) , Josef Malý (Assistant Professor (Research Fellow)) & Jiří Vlček (Professor) PhD

Pages: 425-435

Published online: 23 Jan 2014

AbstractforCytochrome P450 enzyme regulation by glucocorticoids and consequences in terms of drug interaction | Full Text | References | PDF (374.9 KB)

1032 Views
39 CrossRef citations
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Drug Evaluations

Ondansetron: a review of pharmacokinetics and clinical experience in postoperative nausea and vomiting

M Christofaki & A Papaioannou MD PhD DEAA

Pages: 437-444

Published online: 28 Jan 2014

AbstractforOndansetron: a review of pharmacokinetics and clinical experience in postoperative nausea and vomiting | Full Text | References | PDF (293.2 KB)

1509 Views
27 CrossRef citations
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The pharmacokinetics of edoxaban for the prevention and treatment of venous thromboembolism

Gines Escolar (Senior Consultant) MD PhD, Maribel Diaz-Ricart (Consultant, Pharmacist) PhD, Eduardo Arellano-Rodrigo (Specialist, Hematologist) MD PhD & Ana M Galán (Associated Scientist, Biochemist) PhD

Pages: 445-458

Published online: 28 Jan 2014

AbstractforThe pharmacokinetics of edoxaban for the prevention and treatment of venous thromboembolism | Full Text | References | PDF (453.8 KB)

405 Views
5 CrossRef citations
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Lacosamide for the treatment of epilepsy

Stefano de Biase MD, Gian Luigi Gigli MD, Mariarosaria Valente MD & Giovanni Merlino MD PhD

Pages: 459-468

Published online: 30 Jan 2014

Abstractfor Lacosamide for the treatment of epilepsy | Full Text | References | PDF (278.3 KB)

402 Views
23 CrossRef citations
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Vandetanib for the treatment of thyroid cancer: an update

Spyridon Karras MD, Panagiotis Anagnostis & Gerasimos E Krassas (Professor)

Pages: 469-481

Published online: 06 Feb 2014

Abstractfor Vandetanib for the treatment of thyroid cancer: an update | Full Text | References | PDF (401.1 KB)

409 Views
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Pharmacokinetic evaluation of vincristine for the treatment of lymphoid malignancies

Rabih Said (Associate Professor) MD & Apostolia Maria Tsimberidou (Associate Professor) MD PhD

Pages: 483-494

Published online: 10 Feb 2014

AbstractforPharmacokinetic evaluation of vincristine for the treatment of lymphoid malignancies | Full Text | References | PDF (490.6 KB)

617 Views
41 CrossRef citations
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Appendix

Correction

Erratum

Page: 495

Published online: 30 Jan 2014

CitationforErratum | Full Text | PDF (31.4 KB)

360 Views
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Free Access

Research Article

Article

Page: i

Published online: 14 Feb 2014

46 Views
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