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Expert Opinion on Drug Metabolism & Toxicology
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Volume 11, Issue 8

Expert Opinion on Drug Metabolism & Toxicology

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Expert Opinion on Drug Metabolism & Toxicology, Volume 11, Issue 8 (2015)

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Expert Opinion on Drug Metabolism & Toxicology, Volume 11, Issue 8 (2015)

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Editorial

Pharmacogenetics in irritable bowel syndrome

Andres Acosta MD PhD & Michael Camilleri MD

Pages: 1187-1191

Published online: 30 Jun 2015

AbstractforPharmacogenetics in irritable bowel syndrome | Full Text | References | PDF (260.6 KB)

1674 Views
4 CrossRef citations
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Original Research

Article

Comparison of the pharmacokinetic and pharmacodynamic profiles of insulin degludec and insulin glargine

Tim Heise, Ulrike Hövelmann, Leszek Nosek, Lidia Hermanski, Susanne G Bøttcher & Hanne Haahr

Pages: 1193-1201

Published online: 18 Jun 2015

AbstractforComparison of the pharmacokinetic and pharmacodynamic profiles of insulin degludec and insulin glargine | Full Text | References | PDF (636.9 KB)

5028 Views
111 CrossRef citations
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Review

Applications of physiologically based pharmacokinetic modeling for the optimization of anti-infective therapies

Darren Michael Moss, Catia Marzolini, Rajith KR Rajoli & Marco Siccardi

Pages: 1203-1217

Published online: 15 Apr 2015

AbstractforApplications of physiologically based pharmacokinetic modeling for the optimization of anti-infective therapies | Full Text | References | PDF (583.5 KB)

463 Views
11 CrossRef citations
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Effect of Cytochrome P450 polymorphism on the action and metabolism of selective serotonin reuptake inhibitors

Kristina Probst-Schendzielorz, Roberto Viviani & Julia C Stingl (Professor)

Pages: 1219-1232

Published online: 01 Jun 2015

AbstractforEffect of Cytochrome P450 polymorphism on the action and metabolism of selective serotonin reuptake inhibitors | Full Text | References | PDF (276 KB)

722 Views
28 CrossRef citations
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Nature and uses of fluorescent dyes for drug transporter studies

Olivier Fardel, Marc Le Vee, Elodie Jouan, Claire Denizot & Yannick Parmentier

Pages: 1233-1251

Published online: 07 Jun 2015

AbstractforNature and uses of fluorescent dyes for drug transporter studies | Full Text | References | PDF (705 KB)

929 Views
30 CrossRef citations
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Methods: for studying pharmacogenetic profiles of combination chemotherapeutic drugs

Antonello Di Paolo MD PhD, Marialuisa Polillo PharmD, Marianna Lastella BSc, Guido Bocci MD PhD, Marzia Del Re PharmD & Romano Danesi MD PhD

Pages: 1253-1267

Published online: 03 Jun 2015

AbstractforMethods: for studying pharmacogenetic profiles of combination chemotherapeutic drugs | Full Text | References | PDF (438.6 KB)

150 Views
2 CrossRef citations
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CYP2C9 polymorphisms and phenytoin metabolism: implications for adverse effects

Valentina Franco BSc PhD & Emilio Perucca MD PhD

Pages: 1269-1279

Published online: 03 Jun 2015

AbstractforCYP2C9 polymorphisms and phenytoin metabolism: implications for adverse effects | Full Text | References | PDF (365.3 KB)

740 Views
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Detecting reactive drug metabolites for reducing the potential for drug toxicity

Mark P Grillo

Pages: 1281-1302

Published online: 25 May 2015

AbstractforDetecting reactive drug metabolites for reducing the potential for drug toxicity | Full Text | References | PDF (1.3 MB) | Supplemental

1714 Views
32 CrossRef citations
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Preclinical studies of dendrimer prodrugs

Chie Kojima (Associate Professor) PhD (Biostudies)

Pages: 1303-1315

Published online: 01 Jun 2015

AbstractforPreclinical studies of dendrimer prodrugs | Full Text | References | PDF (640 KB)

242 Views
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Drug Evaluation

How the pharmacokinetics and receptor-binding profile of lurasidone affect the clinical utility and safety of the drug in the treatment of schizophrenia

Matthew Macaluso (Assistant Professor, Director of Residency Training, Director of Research) DO, Hala Kazanchi (Senior Resident) MD & Sheldon H Preskorn (Professor) MD

Pages: 1317-1327

Published online: 14 Jul 2015

AbstractforHow the pharmacokinetics and receptor-binding profile of lurasidone affect the clinical utility and safety of the drug in the treatment of schizophrenia | Full Text | References | PDF (350.5 KB)

551 Views
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Perampanel for epilepsy with partial-onset seizures: a pharmacokinetic and pharmacodynamic evaluation

Andreas Schulze-Bonhage (Professor) MD, PhD

Pages: 1329-1337

Published online: 25 Jun 2015

AbstractforPerampanel for epilepsy with partial-onset seizures: a pharmacokinetic and pharmacodynamic evaluation | Full Text | References | PDF (387.3 KB)

464 Views
15 CrossRef citations
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Errata

Correction

Erratum

Page: 1169

Published online: 14 Jul 2015

CitationforErratum | Full Text | PDF (28.7 KB)

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Expert Opinion on Drug Metabolism & Toxicology (Vol.11, Iss.8, 2015)

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Expert Opinion on Drug Metabolism & Toxicology, Volume 11, Issue 8 (2015)

Expert Opinion on Drug Metabolism & Toxicology, Volume 11, Issue 8 (2015)

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